{
    "uniprot_canonical_ac": "A0A0G2K628-1", 
    "sequence": {
        "header": "tr|A0A0G2K628-1|A0A0G2K628_RAT Isoform 1 of Similar to Ski protein (Predicted)  OS=Rattus norvegicus OX=10116 GN=Ski PE=1 SV=1 CANONICAL=A0A0G2K628-1", 
        "length": 699, 
        "sequence": "MSSLGGPAAFSARWAQEAYKKESAKEAGAATVPAPVPTAAEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYANKYKRRVPRVSEPPASIRPKTDDTSSQSPASSEKDKQSTWLRTLAGSSNKSLGCAHPRQRLSAFRPWSPAVSASEKETSPHLPALIRDSFYSYKSFETAVAPNVALAPPTQQKVVNSPPCTTVVSRAPEPLTTCIQPRKRKLTMDAPGAPDMLTPVAAAEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLSSPGMHAPPVAAPDAAAHADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLTAALQAKRSLHQELEFLRVAKKEKLREATEAKRSLRKEIERLRAENEKKMKEANESRVRLKRELEQARQVRVCDKGCEAGRLRAKYSAQIEDLQAKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRPRPENSGGESNAELDP"
    }, 
    "uniprot_id": "A0A0G2K628_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "ski oncogene"
            ], 
            "uniprotkb": [
                "Similar to Ski protein (Predicted)", 
                "SKI proto-oncogene"
            ]
        }, 
        "gene": {
            "refseq": [
                "Ski"
            ], 
            "uniprotkb": [
                "Ski", 
                "RGD1565591_predicted", 
                "rCG_31202"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                    "id": "A0A0G2K628", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Similar to Ski protein (Predicted); SKI proto-oncogene."
    }, 
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K628/publications", 
                    "id": "A0A0G2K628", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", 
            "date": "2012", 
            "pmid": "22673903"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K628#A0A0G2K628-1", 
            "isoform_ac": "A0A0G2K628-1", 
            "locus": {
                "end_pos": 172559337, 
                "start_pos": 172623813, 
                "chromosome": "5", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000080591", 
                        "id": "ENSRNOT00000080591", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073651", 
                        "id": "ENSRNOP00000073651", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K628-1|A0A0G2K628_RAT Isoform 1 of Similar to Ski protein (Predicted)  OS=Rattus norvegicus OX=10116 GN=Ski PE=1 SV=1 CANONICAL=A0A0G2K628-1", 
                "length": 699, 
                "sequence": "MSSLGGPAAFSARWAQEAYKKESAKEAGAATVPAPVPTAAEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYANKYKRRVPRVSEPPASIRPKTDDTSSQSPASSEKDKQSTWLRTLAGSSNKSLGCAHPRQRLSAFRPWSPAVSASEKETSPHLPALIRDSFYSYKSFETAVAPNVALAPPTQQKVVNSPPCTTVVSRAPEPLTTCIQPRKRKLTMDAPGAPDMLTPVAAAEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLSSPGMHAPPVAAPDAAAHADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLTAALQAKRSLHQELEFLRVAKKEKLREATEAKRSLRKEIERLRAENEKKMKEANESRVRLKRELEQARQVRVCDKGCEAGRLRAKYSAQIEDLQAKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRPRPENSGGESNAELDP"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:313757", 
            "resource": "KEGG Pathway", 
            "id": "rno:313757", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2173795", 
            "resource": "Reactome", 
            "id": "R-RNO-2173795", 
            "name": "Downregulation of SMAD2/3:SMAD4 transcriptional activity"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-201451", 
            "resource": "Reactome", 
            "id": "R-RNO-201451", 
            "name": "Signaling by BMP"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P12755-1", 
            "protein_name": "Ski oncogene; Proto-oncogene c-Ski.", 
            "sequence": {
                "length": 728, 
                "sequence": "MEAAAGGRGCFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEAYKKESAKEAGAAAVPAPVPAATEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYGNKYKRRVPRVSSEPPASIRPKTDDTSSQSPAPSEKDKPSSWLRTLAGSSNKSLGCVHPRQRLSAFRPWSPAVSASEKELSPHLPALIRDSFYSYKSFETAVAPNVALAPPAQQKVVSSPPCAAAVSRAPEPLATCTQPRKRKLTVDTPGAPETLAPVAAPEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLGSPGARALPSAVPDAAAPADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLSAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQARQARVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRARPEAAGSEGAAELEP"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/31124", 
                    "id": "31124", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2K628/", 
                    "id": "A0A0G2K628", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017449382.1", 
        "ac": "XP_017449382.1", 
        "name": "ski oncogene.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "transcription corepressor activity", 
                        "id": "GO:0003714"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "SMAD binding", 
                        "id": "GO:0046332"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "zinc ion binding", 
                        "id": "GO:0008270"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein kinase binding", 
                        "id": "GO:0019901"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein domain specific binding", 
                        "id": "GO:0019904"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ubiquitin protein ligase binding", 
                        "id": "GO:0031625"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070491", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "repressing transcription factor binding", 
                        "id": "GO:0070491"
                    }
                ], 
                "total": 7, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "transcription factor complex", 
                        "id": "GO:0005667"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "centrosome", 
                        "id": "GO:0005813"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "PML body", 
                        "id": "GO:0016605"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of transcription by RNA polymerase II", 
                        "id": "GO:0000122"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of BMP signaling pathway", 
                        "id": "GO:0030514"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of transforming growth factor beta receptor signaling pathway", 
                        "id": "GO:0030512"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "transcription, DNA-templated", 
                        "id": "GO:0006351"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060395", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "SMAD protein signal transduction", 
                        "id": "GO:0060395"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032926", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of activin receptor signaling pathway", 
                        "id": "GO:0032926"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070207", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein homotrimerization", 
                        "id": "GO:0070207"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of osteoblast differentiation", 
                        "id": "GO:0045668"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010626", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of Schwann cell proliferation", 
                        "id": "GO:0010626"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043388", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of DNA binding", 
                        "id": "GO:0043388"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014902", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
                                "id": "A0A0G2K628", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "myotube differentiation", 
                        "id": "GO:0014902"
                    }
                ], 
                "total": 11, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 243, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 241
        }, 
        {
            "end_pos": 337, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 335
        }, 
        {
            "end_pos": 604, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 602
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017449382.1", 
            "id": "XP_017449382.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2173795", 
            "id": "R-RNO-2173795", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-201451", 
            "id": "R-RNO-201451", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:313757", 
            "id": "rno:313757", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000055340", 
            "id": "ENSRNOG00000055340", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/QIRVCDK/", 
            "id": "QIRVCDK", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014890", 
            "id": "IPR014890", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028760", 
            "id": "IPR028760", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR010919", 
            "id": "IPR010919", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003380", 
            "id": "IPR003380", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009061", 
            "id": "IPR009061", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR037000", 
            "id": "IPR037000", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023216", 
            "id": "IPR023216", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF08782", 
            "id": "PF08782", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF02437", 
            "id": "PF02437", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10005:SF15", 
            "id": "PTHR10005:SF15", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10005", 
            "id": "PTHR10005", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/313757", 
            "id": "313757", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1565591", 
            "id": "1565591", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2K628", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 77368.0, 
        "chemical_mass": 77368.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K628", 
            "name": "Ski; RGD1565591_predicted; rCG_31202.", 
            "locus": {
                "end_pos": 172559135, 
                "start_pos": 172623899, 
                "chromosome": "5", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000055340", 
                        "id": "ENSRNOG00000055340", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}