{ "uniprot_canonical_ac": "A0A0G2K520-1", "sequence": { "header": "tr|A0A0G2K520-1|A0A0G2K520_RAT Isoform 1 of Cytoplasmic polyadenylation element binding protein 2 OS=Rattus norvegicus OX=10116 GN=Cpeb2 PE=1 SV=1 CANONICAL=A0A0G2K520-1", "length": 745, "sequence": "MRDFGFGVLHTALLRSGSPRSSPGGSAYRPFAAGPSATPFGPLSPPPLPVTGFSEAASPFAIPSGGGAASSAASSSSPLVAHQQAVQDELLLGLTQQPARPLSGAAAAEQLPSHHPGGGTNAGVTHLLPSQDFKPSLHHPSSSSASSCCCCCRTSSPQDSKRQQQQLSSQKRKELSRHTRPPPSAKPTRRRTHCPGGGGGFGGPFSAPAVPAPPAMNLPQQQPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSPWSNHQSSGWGTASMSWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNARSYGRRRGRSSLFPIDDSLLDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAEVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN" }, "uniprot_id": "A0A0G2K520_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Cytoplasmic polyadenylation element binding protein 2" ] }, "gene": { "refseq": [], "uniprotkb": [ "Cpeb2" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Cytoplasmic polyadenylation element binding protein 2." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520#A0A0G2JY45-1", "isoform_ac": "A0A0G2JY45-1", "locus": { "end_pos": 72331708, "start_pos": 72380330, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000081878", "id": "ENSRNOT00000081878", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000070514", "id": "ENSRNOP00000070514", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JY45-1|A0A0G2K520_RAT Computationally mapped isoform of Cytoplasmic polyadenylation element binding protein 2 OS=Rattus norvegicus OX=10116 GN=Cpeb2 PE=1 SV=1 CANONICAL=A0A0G2K520-1", "length": 744, "sequence": "MRDFGFGVLHTALLRSGSPRSSPGGSAYRPFAAGPSATPFGPLSPPPLPVTGFSEAASPFAIPSGGGAASSAASSSSPLVAHQQAVQDELLLGLTQQPARPLSGAAAAEQLPSHHPGGGTNAGVTHLLPSQDFKPSLHHPSSSSASSCCCCCRTSSPQDVSKRQQQASSQKRKELSATHAPPPDAKPTPPLHCPGGGGGGFGGPFSAPAVPAPPAMNLPQQQPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSPWSNHQSSGWGTASMSWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNARSYGRRRGRSSLFPIDDSLLDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K520#A0A0G2K520-1", "isoform_ac": "A0A0G2K520-1", "locus": { "end_pos": 72331708, "start_pos": 72380330, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000082653", "id": "ENSRNOT00000082653", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000073259", "id": "ENSRNOP00000073259", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K520-1|A0A0G2K520_RAT Isoform 1 of Cytoplasmic polyadenylation element binding protein 2 OS=Rattus norvegicus OX=10116 GN=Cpeb2 PE=1 SV=1 CANONICAL=A0A0G2K520-1", "length": 745, "sequence": "MRDFGFGVLHTALLRSGSPRSSPGGSAYRPFAAGPSATPFGPLSPPPLPVTGFSEAASPFAIPSGGGAASSAASSSSPLVAHQQAVQDELLLGLTQQPARPLSGAAAAEQLPSHHPGGGTNAGVTHLLPSQDFKPSLHHPSSSSASSCCCCCRTSSPQDSKRQQQQLSSQKRKELSRHTRPPPSAKPTRRRTHCPGGGGGFGGPFSAPAVPAPPAMNLPQQQPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSPWSNHQSSGWGTASMSWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNARSYGRRRGRSSLFPIDDSLLDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAEVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K520#D3ZHK8-1", "isoform_ac": "D3ZHK8-1", "locus": { "end_pos": 72331708, "start_pos": 72380330, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000006727", "id": "ENSRNOT00000006727", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000006727", "id": "ENSRNOP00000006727", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3ZHK8-1|A0A0G2K520_RAT Computationally mapped isoform of Cytoplasmic polyadenylation element binding protein 2 OS=Rattus norvegicus OX=10116 GN=Cpeb2 PE=1 SV=3 CANONICAL=A0A0G2K520-1", "length": 717, "sequence": "MRDFGFGVLHTALLRSGSPRSSPGGSAYRPFAAGPSATPFGPLSPPPLPVTGFSEAASPPPLPGHPWSVQTRPPPPPQPPPAPQQQPSQQQQPPQQPPQPQPPGSSAATPGGGGGAGGSLSAMPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCAGLSVPAGGGGGGGGFGGPFSAPAVPAPPAMNLPQQQPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSPWSNHQSSGWGTASMSWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNARSYGRRRGRSSLFPIDDSLLDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN" } } ], "pathway": [], "function": [], "orthologs": [], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "translation repressor activity, mRNA regulatory element binding", "id": "GO:0000900" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "translation factor activity, RNA binding", "id": "GO:0008135" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "ribosome binding", "id": "GO:0043022" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "mRNA 3'-UTR binding", "id": "GO:0003730" } ], "total": 4, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "synapse", "id": "GO:0045202" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "neuron projection", "id": "GO:0043005" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990124", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "messenger ribonucleoprotein complex", "id": "GO:1990124" } ], "total": 5, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "cellular response to insulin stimulus", "id": "GO:0032869" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "id": "A0A0G2K520", "database": "UniProtKB" } ], "name": "cellular response to hypoxia", "id": "GO:0071456" } ], "total": 3, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 351, "annotation": "n_glycosylation_sequon", "start_pos": 349 }, { "end_pos": 579, "annotation": "n_glycosylation_sequon", "start_pos": 577 }, { "end_pos": 704, "annotation": "n_glycosylation_sequon", "start_pos": 702 } ], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000005043", "id": "ENSRNOG00000005043", "database": "Bgee" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "id": "IPR035979", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "id": "IPR000504", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR032296", "id": "IPR032296", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR034819", "id": "IPR034819", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR038446", "id": "IPR038446", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "id": "IPR012677", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF16366", "id": "PF16366", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF16367", "id": "PF16367", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12566", "id": "PTHR12566", "database": "PANTHER" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307485", "id": "1307485", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K520", "disease": [], "mass": { "monoisotopic_mass": 81304.0, "chemical_mass": 81304.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K520", "name": "Cpeb2.", "locus": { "end_pos": 72331705, "start_pos": 72380330, "chromosome": "14", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000005043", "id": "ENSRNOG00000005043", "database": "Ensembl Gene" } ] } } ] }