{ "uniprot_canonical_ac": "A0A0G2K3B7-1", "sequence": { "header": "tr|A0A0G2K3B7-1|A0A0G2K3B7_RAT Isoform 1 of Protein Wnt OS=Rattus norvegicus OX=10116 GN=Wnt7b PE=3 SV=1 CANONICAL=A0A0G2K3B7-1", "length": 353, "sequence": "MLLLSPRSALVSVYCPQIFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGIDECQHQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVLEDRMKLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK" }, "uniprot_id": "A0A0G2K3B7_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Protein Wnt" ] }, "gene": { "refseq": [], "uniprotkb": [ "Wnt7b" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Protein Wnt." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7#A0A0G2K3B7-1", "isoform_ac": "A0A0G2K3B7-1", "locus": { "end_pos": 126423421, "start_pos": 126461654, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000081032", "id": "ENSRNOT00000081032", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000072573", "id": "ENSRNOP00000072573", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K3B7-1|A0A0G2K3B7_RAT Isoform 1 of Protein Wnt OS=Rattus norvegicus OX=10116 GN=Wnt7b PE=3 SV=1 CANONICAL=A0A0G2K3B7-1", "length": 353, "sequence": "MLLLSPRSALVSVYCPQIFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGIDECQHQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVLEDRMKLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7#E9PU66-1", "isoform_ac": "E9PU66-1", "locus": { "end_pos": 126423421, "start_pos": 126465723, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000021196", "id": "ENSRNOT00000021196", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000021196", "id": "ENSRNOP00000021196", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9PU66-1|A0A0G2K3B7_RAT Computationally mapped isoform of Protein Wnt OS=Rattus norvegicus OX=10116 GN=Wnt7b PE=3 SV=3 CANONICAL=A0A0G2K3B7-1", "length": 346, "sequence": "FRKWIFYVFLCLGPSLYVKLRALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGIDECQHQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVLEDRMKLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3238698", "resource": "Reactome", "id": "R-RNO-3238698", "name": "WNT ligand biogenesis and trafficking" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7#function", "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7#function", "id": "A0A0G2K3B7", "database": "UniProtKB" } ] } ], "orthologs": [], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "frizzled binding", "id": "GO:0005109" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "receptor ligand activity", "id": "GO:0048018" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "extracellular space", "id": "GO:0005615" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" } ], "total": 3, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032536", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "regulation of cell projection size", "id": "GO:0032536" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "neuron projection development", "id": "GO:0031175" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "positive regulation of JNK cascade", "id": "GO:0046330" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "neuron projection morphogenesis", "id": "GO:0048812" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051384", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "response to glucocorticoid", "id": "GO:0051384" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "neuron differentiation", "id": "GO:0030182" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "Wnt signaling pathway", "id": "GO:0016055" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007257", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "activation of JUN kinase activity", "id": "GO:0007257" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "cell fate commitment", "id": "GO:0045165" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071300", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "cellular response to retinoic acid", "id": "GO:0071300" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K3B7", "id": "A0A0G2K3B7", "database": "UniProtKB" } ], "name": "canonical Wnt signaling pathway", "id": "GO:0060070" }, { "url": 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