{ "uniprot_canonical_ac": "A0A0G2K2S7-1", "sequence": { "header": "tr|A0A0G2K2S7-1|A0A0G2K2S7_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Olr1320 PE=3 SV=1 CANONICAL=A0A0G2K2S7-1", "length": 312, "sequence": "MAKDNQSRVTEFILAGLTDKAELQLPMFLLFLGIYLFTVLGNLGMIILILLSSHLHTPMYFFLSSLSFIDLCYSTIITPKMLVNFVTTKNVISYQECMTQLYFFIAFVISECHMLAAMAYDRYVAICNPLLYNVTMSYQVCARMVGGVYGMGFIGAAIHTLCMLRVVFCKNNIINHYFCDLFPLMELACSSTYVNEVVLLCLSAFNIFIPTLTILGSYVFIIASILRIKSTEGRFKAFSTCSSHFCAVSVFFGSLAFMYLQPFSVSSKDKGKVSSVFYTTVVPMLNPMIYSLRNRDVKLALNKIFQKRKLHV" }, "uniprot_id": "A0A0G2K2S7_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "olfactory receptor Olr1320", "olfactory receptor gene Olr1320" ], "uniprotkb": [ "Olfactory receptor" ] }, "gene": { "refseq": [ "Olr1320" ], "uniprotkb": [ "Olr1320" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Olfactory receptor." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7#A0A0G2K2S7-1", "isoform_ac": "A0A0G2K2S7-1", "locus": { "end_pos": 43628182, "start_pos": 43629117, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000090359", "id": "ENSRNOT00000090359", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000072358", "id": "ENSRNOP00000072358", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K2S7-1|A0A0G2K2S7_RAT Isoform 1 of Olfactory receptor OS=Rattus norvegicus OX=10116 GN=Olr1320 PE=3 SV=1 CANONICAL=A0A0G2K2S7-1", "length": 312, "sequence": "MAKDNQSRVTEFILAGLTDKAELQLPMFLLFLGIYLFTVLGNLGMIILILLSSHLHTPMYFFLSSLSFIDLCYSTIITPKMLVNFVTTKNVISYQECMTQLYFFIAFVISECHMLAAMAYDRYVAICNPLLYNVTMSYQVCARMVGGVYGMGFIGAAIHTLCMLRVVFCKNNIINHYFCDLFPLMELACSSTYVNEVVLLCLSAFNIFIPTLTILGSYVFIIASILRIKSTEGRFKAFSTCSSHFCAVSVFFGSLAFMYLQPFSVSSKDKGKVSSVFYTTVVPMLNPMIYSLRNRDVKLALNKIFQKRKLHV" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:300621", "resource": "KEGG Pathway", "id": "rno:300621", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW89-1", "protein_name": "Olfactory receptor.", "sequence": { "length": 312, "sequence": "MAKDNQSRVTEFILVGLTDKPELQLPMFLLFLGIYLFTVLGNLGMIILILLSSHLHTPMYFFLSNLSFIDLCYSTIVTPKMLVNFVTTKNVISYQECMTQLYFFIAFAISECHMLAAMAYDRYVAICNPLLYNVTMSFQVCARMVGGVYGIGIVGAAIHTLCMLRVVFCKANIINHYFCDLFPLMELACSSTYVNEVVLLCLSAFNFFIPNLTILGSYVFIIITILRIKSTEGRFKAFSTCSSHFCAVSVFFGSLAFMYLQPFSVNSKDKGKVSSVFYTTVVPMLNPMIYSLRNRDVKLALNKIFQKKKILV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/133634", "id": "133634", "database": "MGI" } ], "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q60895-1", "protein_name": "Olfactory receptor 150; Odorant receptor M93; Olfactory receptor 171-18; Olfactory receptor 7I.", "sequence": { "length": 312, "sequence": "MAYSNQSRVTEFIISGLTNKPELQLPLFLLFLGIYLFTVLGNLGMIILILLSSHLHTPMYFFLSSLSFIDLCYSTIITPKMLVNFVTTKNVISYQECMTQLYFFIAFVISECHMLAAMAYDRYVAICNPLLYNVTMSYQVCSWMVGGVYGMGFIGAAIHTFCMLRVVFCKDNIINHYFCDLFPLMELACSSTYVNEVVLLSLSAFNIFIPTLTILGSYIFIIISILRIKSTEGRFKAFSTCSSHFSAVSVFFGSLAFMYLQPFSVSSKDKGKVSSVFYTTIVPMLNPMIYSLRNRDVKLALNKLFQKKKFHV" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A0G2K2S7/", "id": "A0A0G2K2S7", "database": "OMA" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000471.1", "ac": "NP_001000471.1", "name": "olfactory receptor Olr1320; olfactory receptor gene Olr1320.", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]." }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001591", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "dopamine neurotransmitter receptor activity, coupled via Gi/Go", "id": "GO:0001591" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004935", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "adrenergic receptor activity", "id": "GO:0004935" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035240", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "dopamine binding", "id": "GO:0035240" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "olfactory receptor activity", "id": "GO:0004984" } ], "total": 4, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005887", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "integral component of plasma membrane", "id": "GO:0005887" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "synaptic vesicle membrane", "id": "GO:0030672" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060158", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "phospholipase C-activating dopamine receptor signaling pathway", "id": "GO:0060158" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007194", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "negative regulation of adenylate cyclase activity", "id": "GO:0007194" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042493", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "response to drug", "id": "GO:0042493" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071880", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "adenylate cyclase-activating adrenergic receptor signaling pathway", "id": "GO:0071880" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001963", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "synaptic transmission, dopaminergic", "id": "GO:0001963" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014059", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "regulation of dopamine secretion", "id": "GO:0014059" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048149", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "behavioral response to ethanol", "id": "GO:0048149" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051967", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "negative regulation of synaptic transmission, glutamatergic", "id": "GO:0051967" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "response to toxic substance", "id": "GO:0009636" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051482", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway", "id": "GO:0051482" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048148", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "behavioral response to cocaine", "id": "GO:0048148" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007195", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "adenylate cyclase-inhibiting dopamine receptor signaling pathway", "id": "GO:0007195" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043266", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "regulation of potassium ion transport", "id": "GO:0043266" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051481", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "negative regulation of cytosolic calcium ion concentration", "id": "GO:0051481" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901386", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "id": "A0A0G2K2S7", "database": "UniProtKB" } ], "name": "negative regulation of voltage-gated calcium channel activity", "id": "GO:1901386" } ], "total": 16, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 7, "annotation": "n_glycosylation_sequon", "start_pos": 5 }, { "end_pos": 135, "annotation": "n_glycosylation_sequon", "start_pos": 133 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000471.1", "id": "NP_001000471.1", "database": "RefSeq" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?rno:300621", "id": "rno:300621", "database": "KEGG Pathway" }, { "url": "https://omabrowser.org/oma/group/KANIVNH/", "id": "KANIVNH", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "id": "IPR000276", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "id": "IPR017452", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "id": "IPR000725", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF13853", "id": "PF13853", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/300621", "id": "300621", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1333918", "id": "1333918", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K2S7", "disease": [], "mass": { "monoisotopic_mass": 35302.0, "chemical_mass": 35302.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2S7", "name": "Olr1320.", "locus": { "end_pos": 43629120, "start_pos": 43628182, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000058809", "id": "ENSRNOG00000058809", "database": "Ensembl Gene" } ] } } ] }