{ "uniprot_canonical_ac": "A0A0G2K2P5-1", "sequence": { "header": "sp|A0A0G2K2P5-1|ZO1_RAT Isoform 1 of Tight junction protein ZO-1 OS=Rattus norvegicus OX=10116 GN=Tjp1 PE=1 SV=1 CANONICAL=A0A0G2K2P5-1", "length": 1765, "sequence": "MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSHPDPDPVSDNEDDSYDEDVHDPRSGRGALANRRGEKSWARDRSASRDRSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHSVRSHDRPPRRSQSRSPDQRSEPSDHSTQSPQQPSNGSLRSREEERMSKPGAVSTPVKHVDDHTPKAVEEVTVEKHEKQTPTLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIVPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEPRDAGTDHRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHTSDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSPQAQPQAIHRIDSPGLKTASQQKAEASSPVPYLSPETNPASSASAVKHNVNLTNVNLEEPTPAPPTSHVSQADCLGAPSPEAPHTMLRDEGVSLPSHVDPAKVYRKEPYPEEMMRQNHILKQPALGHPGQRLDKEPNPAYDPQLPYVEKQASRDLEQPPYRYESSSYTDQFSRNYDHRLRFEDRVPTYEDQWSYYDDKQPYPTRPFDTQHPRDLDSRQHPEEASERGYFQRFEEPAPLPYDSRPRYEQLPRTSTLRHEEQPTSGYEVHNRYRPEAQPYAPAGPKSSEPKQYFDQYPRSYEQVPPPGFTSKTGHYEPLHGAAVVPPLIPSSQHKPEVLPSATKPQPPPPALTEEEEDPAMKPQSVLTRVKMFENKRSASLENKKDVNDTASFKPPEVASKPPSASLVGPKPVSQTQFSEHDKTLYRLPEPQKPQAKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFESKPPAHIPAGHHSEPAKPVHSQSQPNFSSYSSKGKPETDAMDRSFSEKRYDPTQAMPPPPPLPSQYSQPVPPLSNSSLHIHSKAAQSEGNSVSLDFQNSYISKPDPPPSQSKPATFRPPTREDPPQTFYPQKSFPDKASVNGAEQTQKTITPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETVHKPELSSKPPPSPKTLMKAHSSTQPPEFDSGVETFSVHTDKPKYQINNISTMPKAVPVSPSAVEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGIEQEIYFKVCRDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCASMTPDGWSFALKSSDSSSGDPKTWQNKCLPGDPNYLVGANCVSVLIDHF" }, "uniprot_id": "ZO1_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Tight junction protein ZO-1", "Zonula occludens protein 1", "Tight junction protein 1", "Zona occludens protein 1" ] }, "gene": { "refseq": [], "uniprotkb": [ "Tjp1" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Tight junction protein ZO-1; Zonula occludens protein 1; Tight junction protein 1; Zona occludens protein 1." }, "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5/publications", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012", "pmid": "22673903" }, { "title": "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/16641100", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5/publications", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "authors": "Wang G., Shen R.F., Knepper M.A., Shen R.-F., Hoffert J.D., Pisitkun T.", "date": "2006", "pmid": "16641100" }, { "title": "The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/9707407", "journal": "Curr. Biol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5/publications", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "authors": "Giepmans B.N., Moolenaar W.H.", "date": "1998", "pmid": "9707407" }, { "title": "Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/3528172", "journal": "J. Cell Biol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5/publications", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "authors": "Siliciano J.D., Mooseker M.S., Goodenough D.A., Stevenson B.R.", "date": "1986", "pmid": "3528172" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5#A0A0G2K2P5-1", "isoform_ac": "A0A0G2K2P5-1", "locus": { "end_pos": 126147893, "start_pos": 126227253, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000087332", "id": "ENSRNOT00000087332", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000072324", "id": "ENSRNOP00000072324", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A0A0G2K2P5-1|ZO1_RAT Isoform 1 of Tight junction protein ZO-1 OS=Rattus norvegicus OX=10116 GN=Tjp1 PE=1 SV=1 CANONICAL=A0A0G2K2P5-1", "length": 1765, "sequence": "MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSHPDPDPVSDNEDDSYDEDVHDPRSGRGALANRRGEKSWARDRSASRDRSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHSVRSHDRPPRRSQSRSPDQRSEPSDHSTQSPQQPSNGSLRSREEERMSKPGAVSTPVKHVDDHTPKAVEEVTVEKHEKQTPTLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIVPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEPRDAGTDHRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHTSDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSPQAQPQAIHRIDSPGLKTASQQKAEASSPVPYLSPETNPASSASAVKHNVNLTNVNLEEPTPAPPTSHVSQADCLGAPSPEAPHTMLRDEGVSLPSHVDPAKVYRKEPYPEEMMRQNHILKQPALGHPGQRLDKEPNPAYDPQLPYVEKQASRDLEQPPYRYESSSYTDQFSRNYDHRLRFEDRVPTYEDQWSYYDDKQPYPTRPFDTQHPRDLDSRQHPEEASERGYFQRFEEPAPLPYDSRPRYEQLPRTSTLRHEEQPTSGYEVHNRYRPEAQPYAPAGPKSSEPKQYFDQYPRSYEQVPPPGFTSKTGHYEPLHGAAVVPPLIPSSQHKPEVLPSATKPQPPPPALTEEEEDPAMKPQSVLTRVKMFENKRSASLENKKDVNDTASFKPPEVASKPPSASLVGPKPVSQTQFSEHDKTLYRLPEPQKPQAKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFESKPPAHIPAGHHSEPAKPVHSQSQPNFSSYSSKGKPETDAMDRSFSEKRYDPTQAMPPPPPLPSQYSQPVPPLSNSSLHIHSKAAQSEGNSVSLDFQNSYISKPDPPPSQSKPATFRPPTREDPPQTFYPQKSFPDKASVNGAEQTQKTITPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETVHKPELSSKPPPSPKTLMKAHSSTQPPEFDSGVETFSVHTDKPKYQINNISTMPKAVPVSPSAVEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGIEQEIYFKVCRDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCASMTPDGWSFALKSSDSSSGDPKTWQNKCLPGDPNYLVGANCVSVLIDHF" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5#F1M4A0-1", "isoform_ac": "F1M4A0-1", "locus": { "end_pos": 126147893, "start_pos": 126211428, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000014988", "id": "ENSRNOT00000014988", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000014988", "id": "ENSRNOP00000014988", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F1M4A0-1|ZO1_RAT Computationally mapped isoform of Tight junction protein ZO-1 OS=Rattus norvegicus OX=10116 GN=Tjp1 PE=1 SV=2 CANONICAL=A0A0G2K2P5-1", "length": 1733, "sequence": "MEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSHPDPDPVSDNEDDSYDEDVHDPRSGRGALANRRGEKSWARDRSASRDRSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHSVRSHDRPPRRSQSRSPDQRSEPSDHSTQSPQQPSNGSLRSREEERMSKPGAVSTPVKHVDDHTPKAVEEVTVEKHEKQTPTLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIVPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEPRDAGTDHRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHTSDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSPQAQPQAIHRIDSPGLKTASQQKAEASSPVPYLSPETNPASSASAVKHNVNLTNVNLEEPTPAPPTSHVSQADCLGAPSPEAPHTMLRDEGVSLPSHVDPAKVYRKEPYPEEMMRQNHILKQPALGHPGQRLDKEPNPAYDPQLPYVEKQASRDLEQPPYRYESSSYTDQFSRNYDHRLRFEDRVPTYEDQWSYYDDKQPYPTRPFDTQHPRDLDSRQHPEEASERGYFQRFEEPAPLPYDSRPRYEQLPRTSTLRHEEQPTSGYEVHNRYRPEAQPYAPAGPKSSEPKQYFDQYPRSYEQVPPPGFTSKTGHYEPLHGAAVVPPLIPSSQHKPEVLPSATKPQPPPPALTEEEEDPAMKPQSVLTRVKMFENKRSASLENKKDVNDTASFKPPEVASKPPSASLVGPKPVSQTQFSEHDKTLYRLPEPQKPQAKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFESKPPAHIPAGHHSEPAKPVHSQSQPNFSSYSSKGKPETDAMDRSFSEKRYDPTQAMPPPPPLPSQYSQPVPPLSNSSLHIHSKAAQSEGNSVSLDFQNSYISKPDPPPSQSKPATFRPPTREDPPQTFYPQKSFPDKASVNGAEQTQKTITPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETVHKPELSSKPPPSPKTLMKAHSSTQPPEFDSGVETFSVHTDKPKYQINNISTMPKAVPVSPSAVEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGIEQEIYFKVCRDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANCVSVLIDHF" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-191650", "resource": "Reactome", "id": "R-RNO-191650", "name": "Regulation of gap junction activity" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-351906", "resource": "Reactome", "id": "R-RNO-351906", "name": "Apoptotic cleavage of cell adhesion proteins" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2028269", "resource": "Reactome", "id": "R-RNO-2028269", "name": "Signaling by Hippo" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5#function", "annotation": "TjpP1, Tjp2, and Tjp3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton (PubMed:9707407). The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Necessary for lumenogenesis, and particularly efficient epithelial polarization and barrier formation (By similarity). Plays a role in the regulation of cell migration by targeting Cdc42bpb to the leading edge of migrating cells (By similarity). Plays an important role in podosome formation and associated function, thus regulating cell adhesion and matrix remodeling (By similarity). With Tjp2 and Tjp3, participates to the junctional retention and stability of the transcription factor Dbpa, but is not involved in its shuttling to the nucleus (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5#function", "id": "A0A0G2K2P5", "database": "UniProtKB" } ] } ], "orthologs": [], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008022", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "protein C-terminus binding", "id": "GO:0008022" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071253", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "connexin binding", "id": "GO:0071253" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "protein domain specific binding", "id": "GO:0019904" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "kinase activity", "id": "GO:0016301" } ], "total": 5, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "bicellular tight junction", "id": "GO:0005923" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "gap junction", "id": "GO:0005921" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014704", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "intercalated disc", "id": "GO:0014704" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "apical plasma membrane", "id": "GO:0016324" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046581", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "intercellular canaliculus", "id": "GO:0046581" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005913", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "cell-cell adherens junction", "id": "GO:0005913" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "protein-containing complex", "id": "GO:0032991" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "apicolateral plasma membrane", "id": "GO:0016327" } ], "total": 11, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "response to lipopolysaccharide", "id": "GO:0032496" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042493", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "response to drug", "id": "GO:0042493" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "response to ethanol", "id": "GO:0045471" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "cellular response to glucose stimulus", "id": "GO:0071333" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043116", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "negative regulation of vascular permeability", "id": "GO:0043116" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071000", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "response to magnetism", "id": "GO:0071000" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "sensory perception of sound", "id": "GO:0007605" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001825", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2P5", "id": "A0A0G2K2P5", "database": "UniProtKB" } ], "name": "blastocyst formation", "id": "GO:0001825" } ], "total": 8, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 235, "annotation": "n_glycosylation_sequon", "start_pos": 233 }, { "end_pos": 241, "annotation": "n_glycosylation_sequon", "start_pos": 239 }, { "end_pos": 284, "annotation": "n_glycosylation_sequon", "start_pos": 282 }, { "end_pos": 337, "annotation": "n_glycosylation_sequon", "start_pos": 335 }, { "end_pos": 412, "annotation": "n_glycosylation_sequon", "start_pos": 410 }, { "end_pos": 894, "annotation": "n_glycosylation_sequon", "start_pos": 892 }, { "end_pos": 952, "annotation": "n_glycosylation_sequon", "start_pos": 950 }, { "end_pos": 1287, "annotation": "n_glycosylation_sequon", "start_pos": 1285 }, { "end_pos": 1395, "annotation": "n_glycosylation_sequon", "start_pos": 1393 }, { 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