{ "uniprot_canonical_ac": "A0A0G2K2H4-1", "sequence": { "header": "tr|A0A0G2K2H4-1|A0A0G2K2H4_RAT Isoform 1 of Endoplasmic reticulum to nucleus-signaling 1 OS=Rattus norvegicus OX=10116 GN=Ern1 PE=2 SV=1 CANONICAL=A0A0G2K2H4-1", "length": 977, "sequence": "MPARWLLLLLALLLLPPGPGSFGRASTVTLPEALLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEKIQLLQQQQLPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQTYYWHEPTEAQPPGIPDAL" }, "uniprot_id": "A0A0G2K2H4_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "serine/threonine-protein kinase/endoribonuclease IRE1 isoform X2" ], "uniprotkb": [ "Endoplasmic reticulum to nucleus-signaling 1", "Similar to protein kinase/endoribonuclease(IRE1) alpha (Predicted), isoform CRA_a", "Serine/threonine-protein kinase/endoribonuclease" ] }, "gene": { "refseq": [ "Ern1", "RGD1559716" ], "uniprotkb": [ "Ern1", "RGD1559716_predicted", "rCG_35298", "RGD1559716" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Endoplasmic reticulum to nucleus-signaling 1; Similar to protein kinase/endoribonuclease(IRE1) alpha (Predicted), isoform CRA_a; Serine/threonine-protein kinase/endoribonuclease." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4#A0A0G2K2H4-1", "isoform_ac": "A0A0G2K2H4-1", "locus": { "end_pos": 94592379, "start_pos": 94681777, "chromosome": "10", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000085736", "id": "ENSRNOT00000085736", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000072244", "id": "ENSRNOP00000072244", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K2H4-1|A0A0G2K2H4_RAT Isoform 1 of Endoplasmic reticulum to nucleus-signaling 1 OS=Rattus norvegicus OX=10116 GN=Ern1 PE=2 SV=1 CANONICAL=A0A0G2K2H4-1", "length": 977, "sequence": "MPARWLLLLLALLLLPPGPGSFGRASTVTLPEALLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEKIQLLQQQQLPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQTYYWHEPTEAQPPGIPDAL" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4#F1LSY7-1", "isoform_ac": "F1LSY7-1", "locus": { "end_pos": 94592379, "start_pos": 94652658, "chromosome": "10", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000017371", "id": "ENSRNOT00000017371", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000017371", "id": "ENSRNOP00000017371", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F1LSY7-1|A0A0G2K2H4_RAT Computationally mapped isoform of Endoplasmic reticulum to nucleus-signaling 1 OS=Rattus norvegicus OX=10116 GN=Ern1 PE=2 SV=2 CANONICAL=A0A0G2K2H4-1", "length": 965, "sequence": "MRRCNDIQSFGRASTVTLPEALLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVGQTSENTPTTVSQDVEEKLPRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQFQKELEKIQLLQQQQLPFHPHGDLTQDPDFLDSSGLFSESSGTSSPSPSPRASNHSLNSSSSASKAGTSPSLEPDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACSLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKRHHYRELPLEVQETLGSIPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQTYYWHEPTEAQPPGIPDAL" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-381070", "resource": "Reactome", "id": "R-RNO-381070", "name": "IRE1alpha activates chaperones" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q9EQY0-1", "protein_name": "Serine/threonine-protein kinase/endoribonuclease IRE1; Ire1-alpha; IRE1a; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1.", "sequence": { "length": 977, "sequence": "MPARWLLLLLALLLPPPGPGSFGRTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQGEVLRKVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINIVGQTSDNTPTTVSQDVEEKLARAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSVHQQRQLQHQQFQKELEKIQLLQQQQLPFHPHGDLTQDPEFLDSSGPFSESSGTSSPSPSPRASNHSLHPSSSASRAGTSPSLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGNHPFGKSLQRQANILLGACNLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPHLLSHTYQAMELCRHERLFQTYYWHEPTEPQPPVIPYAL" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/55580", "id": "55580", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0A0G2K2H4/", "id": "A0A0G2K2H4", "database": "OMA" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "O75460-1", "protein_name": "Serine/threonine-protein kinase/endoribonuclease IRE1; Ire1-alpha; IRE1a; Inositol-requiring protein 1; hIRE1p; Endoplasmic reticulum-to-nucleus signaling 1.", "sequence": { "length": 977, "sequence": "MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFHEPPEPQPPVTPDAL" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/55580", "id": "55580", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0A0G2K2H4/", "id": "A0A0G2K2H4", "database": "OMA" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006247696.1", "ac": "XP_006247696.1", "name": "serine/threonine-protein kinase/endoribonuclease IRE1 isoform X2.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "protein kinase activity", "id": "GO:0004672" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "protein serine/threonine kinase activity", "id": "GO:0004674" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "unfolded protein binding", "id": "GO:0051082" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "endoribonuclease activity", "id": "GO:0004521" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005161", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "platelet-derived growth factor receptor binding", "id": "GO:0005161" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "magnesium ion binding", "id": "GO:0000287" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "enzyme binding", "id": "GO:0019899" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "protein homodimerization activity", "id": "GO:0042803" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043531", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "ADP binding", "id": "GO:0043531" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "Hsp90 protein binding", "id": "GO:0051879" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "Hsp70 protein binding", "id": "GO:0030544" } ], "total": 12, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990604", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "IRE1-TRAF2-ASK1 complex", "id": "GO:1990604" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "endoplasmic reticulum membrane", "id": "GO:0005789" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "mitochondrion", "id": "GO:0005739" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030176", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "integral component of endoplasmic reticulum membrane", "id": "GO:0030176" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "nuclear inner membrane", "id": "GO:0005637" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990597", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "AIP1-IRE1 complex", "id": "GO:1990597" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990630", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "IRE1-RACK1-PP2A complex", "id": "GO:1990630" } ], "total": 7, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036498", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "IRE1-mediated unfolded protein response", "id": "GO:0036498" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070059", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "id": "GO:0070059" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098787", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "mRNA cleavage involved in mRNA processing", "id": "GO:0098787" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "positive regulation of RNA splicing", "id": "GO:0033120" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070054", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "mRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0070054" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901142", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "insulin metabolic process", "id": "GO:1901142" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990579", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "peptidyl-serine trans-autophosphorylation", "id": "GO:1990579" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "cellular response to glucose stimulus", "id": "GO:0071333" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007050", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "cell cycle arrest", "id": "GO:0007050" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904707", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "positive regulation of vascular smooth muscle cell proliferation", "id": "GO:1904707" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001935", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "endothelial cell proliferation", "id": "GO:0001935" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035924", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "cellular response to vascular endothelial growth factor stimulus", "id": "GO:0035924" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900103", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "positive regulation of endoplasmic reticulum unfolded protein response", "id": "GO:1900103" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007257", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K2H4", "id": "A0A0G2K2H4", "database": "UniProtKB" } ], "name": "activation of JUN kinase 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