{
    "uniprot_canonical_ac": "A0A0G2K2A5-1", 
    "sequence": {
        "header": "tr|A0A0G2K2A5-1|A0A0G2K2A5_RAT Isoform 1 of Ubiquitin carboxyl-terminal hydrolase  OS=Rattus norvegicus OX=10116 GN=Uchl5 PE=1 SV=1 CANONICAL=A0A0G2K2A5-1", 
        "length": 340, 
        "sequence": "MSGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK"
    }, 
    "uniprot_id": "A0A0G2K2A5_RAT", 
    "enzyme_annotation": [
        {
            "ec": "3.4.19.12", 
            "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)."
        }, 
        {
            "ec": "3.4.19.12", 
            "activity": ""
        }
    ], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Ubiquitin carboxyl-terminal hydrolase", 
                "3.4.19.12"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "Uchl5"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                    "id": "A0A0G2K2A5", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5#A0A0G2K2A5-1", 
            "isoform_ac": "A0A0G2K2A5-1", 
            "locus": {
                "end_pos": 60545834, 
                "start_pos": 60603237, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000077153", 
                        "id": "ENSRNOT00000077153", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072164", 
                        "id": "ENSRNOP00000072164", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K2A5-1|A0A0G2K2A5_RAT Isoform 1 of Ubiquitin carboxyl-terminal hydrolase  OS=Rattus norvegicus OX=10116 GN=Uchl5 PE=1 SV=1 CANONICAL=A0A0G2K2A5-1", 
                "length": 340, 
                "sequence": "MSGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5#Q5HZY3-1", 
            "isoform_ac": "Q5HZY3-1", 
            "locus": {
                "end_pos": 60568229, 
                "start_pos": 60599553, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000004881", 
                        "id": "ENSRNOT00000004881", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000004881", 
                        "id": "ENSRNOP00000004881", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|Q5HZY3-1|A0A0G2K2A5_RAT Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase  OS=Rattus norvegicus OX=10116 GN=Uchl5 PE=1 SV=1 CANONICAL=A0A0G2K2A5-1", 
                "length": 324, 
                "sequence": "MSSNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKIFSCRGRNL"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5689603", 
            "resource": "Reactome", 
            "id": "R-RNO-5689603", 
            "name": "UCH proteinases"
        }
    ], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "thiol-dependent ubiquitin-specific protease activity", 
                        "id": "GO:0004843"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070628", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "proteasome binding", 
                        "id": "GO:0070628"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031597", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosolic proteasome complex", 
                        "id": "GO:0031597"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoplasm", 
                        "id": "GO:0005654"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrion", 
                        "id": "GO:0005739"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Ino80 complex", 
                        "id": "GO:0031011"
                    }
                ], 
                "total": 5, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein deubiquitination", 
                        "id": "GO:0016579"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ubiquitin-dependent protein catabolic process", 
                        "id": "GO:0006511"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021670", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lateral ventricle development", 
                        "id": "GO:0021670"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048853", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "forebrain morphogenesis", 
                        "id": "GO:0048853"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
                                "id": "A0A0G2K2A5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "midbrain development", 
                        "id": "GO:0030901"
                    }
                ], 
                "total": 5, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 78, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 76
        }
    ], 
    "crossref": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5689603", 
            "id": "R-RNO-5689603", 
            "database": "Reactome"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003545", 
            "id": "ENSRNOG00000003545", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02255", 
            "id": "cd02255", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001578", 
            "id": "IPR001578", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036959", 
            "id": "IPR036959", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017390", 
            "id": "IPR017390", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033837", 
            "id": "IPR033837", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", 
            "id": "IPR038765", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041507", 
            "id": "IPR041507", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01088", 
            "id": "PF01088", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF18031", 
            "id": "PF18031", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589", 
            "id": "PTHR10589", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305414", 
            "id": "1305414", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2K2A5", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 38845.0, 
        "chemical_mass": 38845.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2A5", 
            "name": "Uchl5.", 
            "locus": {
                "end_pos": 60603811, 
                "start_pos": 60545635, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000003545", 
                        "id": "ENSRNOG00000003545", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}