{ "uniprot_canonical_ac": "A0A0G2K239-1", "sequence": { "header": "tr|A0A0G2K239-1|A0A0G2K239_RAT Isoform 1 of Terminal nucleotidyltransferase 4B OS=Rattus norvegicus OX=10116 GN=Tent4b PE=4 SV=1 CANONICAL=A0A0G2K239-1", "length": 607, "sequence": "MQIWETTQGLRNLYFNHHCHSSGASSASGGSGSGPGSPGGTAPAPAGMFRSGERPLGGLAVPAEQRDFLPLETTNNNNNHHQPAAWARRAAAGPSASPVPSAPSSPRPAAPLPASESADPASGSSNKRKRDNKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKCYPNNETESILGRIIRVTDEVTTYRDWISKQWGLQNRPEPSCNGPVSSSSATQSSSSDVDSDATPCKTPKQVLCRPPTVSRVGSQDVSLEVSQAVGKMQSTQTTNTANSTNKSQHGSARLFRSSSKGFQALPSVLSNADAHEVLEV" }, "uniprot_id": "A0A0G2K239_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Terminal nucleotidyltransferase 4B" ] }, "gene": { "refseq": [], "uniprotkb": [ "Tent4b" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Terminal nucleotidyltransferase 4B." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239#A0A0G2K239-1", "isoform_ac": "A0A0G2K239-1", "locus": { "end_pos": 19771850, "start_pos": 19832784, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000084657", "id": "ENSRNOT00000084657", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000072094", "id": "ENSRNOP00000072094", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K239-1|A0A0G2K239_RAT Isoform 1 of Terminal nucleotidyltransferase 4B OS=Rattus norvegicus OX=10116 GN=Tent4b PE=4 SV=1 CANONICAL=A0A0G2K239-1", "length": 607, "sequence": "MQIWETTQGLRNLYFNHHCHSSGASSASGGSGSGPGSPGGTAPAPAGMFRSGERPLGGLAVPAEQRDFLPLETTNNNNNHHQPAAWARRAAAGPSASPVPSAPSSPRPAAPLPASESADPASGSSNKRKRDNKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGTPWKRRNYNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKCYPNNETESILGRIIRVTDEVTTYRDWISKQWGLQNRPEPSCNGPVSSSSATQSSSSDVDSDATPCKTPKQVLCRPPTVSRVGSQDVSLEVSQAVGKMQSTQTTNTANSTNKSQHGSARLFRSSSKGFQALPSVLSNADAHEVLEV" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K239#D3ZBG8-1", "isoform_ac": "D3ZBG8-1", "locus": { "end_pos": 19777263, "start_pos": 19789871, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000067582", "id": "ENSRNOT00000067582", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000062854", "id": "ENSRNOP00000062854", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3ZBG8-1|A0A0G2K239_RAT Computationally mapped isoform of Terminal nucleotidyltransferase 4B OS=Rattus norvegicus OX=10116 GN=Tent4b PE=4 SV=1 CANONICAL=A0A0G2K239-1", "length": 421, "sequence": "MSPRPEEEKMRMEVVSRIESVIKELWPSADWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKCYPNNETESILGRIIRVTDEVTTYRDWISKQWGLQNRPEPSCNGNGVTLIVETQQLDKCNNNLSEENEAPGKCRSKASESLSKHSSNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQVLCRPPTVSRVGSQDVSLEVSQAVGKMQSTQTTNTANSTNKSQHGSARLFRSSSKGFQGTAQTSHGALMTSKQHPGKSNTQCYHGKKRRHKRDAPLSELCR" } } ], "pathway": [], "function": [], "orthologs": [], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004652", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "polynucleotide adenylyltransferase activity", "id": "GO:0004652" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "RNA binding", "id": "GO:0003723" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070568", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "guanylyltransferase activity", "id": "GO:0070568" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "nucleolus", "id": "GO:0005730" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "TRAMP complex", "id": "GO:0031499" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" } ], "total": 3, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071044", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "histone mRNA catabolic process", "id": "GO:0071044" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071050", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "snoRNA polyadenylation", "id": "GO:0071050" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033500", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "carbohydrate homeostasis", "id": "GO:0033500" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043630", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process", "id": "GO:0043630" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071076", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "RNA 3' uridylation", "id": "GO:0071076" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006378", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "mRNA polyadenylation", "id": "GO:0006378" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032211", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "negative regulation of telomere maintenance via telomerase", "id": "GO:0032211" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905870", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "positive regulation of 3'-UTR-mediated mRNA stabilization", "id": "GO:1905870" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010587", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "miRNA catabolic process", "id": "GO:0010587" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060212", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "id": "A0A0G2K239", "database": "UniProtKB" } ], "name": "negative regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060212" } ], "total": 10, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 142, "annotation": "n_glycosylation_sequon", "start_pos": 140 }, { "end_pos": 468, "annotation": "n_glycosylation_sequon", "start_pos": 466 }, { "end_pos": 571, "annotation": "n_glycosylation_sequon", "start_pos": 569 }, { "end_pos": 574, "annotation": "n_glycosylation_sequon", "start_pos": 572 } ], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000024212", "id": "ENSRNOG00000024212", "database": "Bgee" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002058", "id": "IPR002058", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002934", "id": "IPR002934", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR040136", "id": "IPR040136", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF01909", "id": "PF01909", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF03828", "id": "PF03828", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23092:SF51", "id": "PTHR23092:SF51", "database": "PANTHER" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309587", "id": "1309587", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K239", "disease": [], "mass": { "monoisotopic_mass": 66065.0, "chemical_mass": 66065.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K239", "name": "Tent4b.", "locus": { "end_pos": 19771677, "start_pos": 19832812, "chromosome": "19", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000024212", "id": "ENSRNOG00000024212", "database": "Ensembl Gene" } ] } } ] }