{
    "uniprot_canonical_ac": "A0A0G2K1Z1-1", 
    "sequence": {
        "header": "tr|A0A0G2K1Z1-1|A0A0G2K1Z1_RAT Isoform 1 of Lysine (K)-specific demethylase 7A  OS=Rattus norvegicus OX=10116 GN=Kdm7a PE=1 SV=1 CANONICAL=A0A0G2K1Z1-1", 
        "length": 867, 
        "sequence": "EHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHRHDYTEADDGSKPVQAGTRAFVKELRSRVFPSADEVIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGYNNGILVSGQDCYQQRGRAKHLTGAGLQFKVFEIKNDHGAPALFFFFFFSVFCSFIARSSLHSLTELKEDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPSVCPVSRPSNDASPPGHSRRKMRRLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDILSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFADRSLYTADSENEEDKKPTKKANVKTEQSSGREAAESDGSPKPLNRIFPSVKSELRSRPSEYSDVSDSEDSGPDCTAVKINFATEESESSGDEKKHEITSNFKEESDVVRNLLQKSQKPSRNEIPVKRECPTSTSTEEEAIQGMLSMAGLHYSTCLQSTDCSGEKNSLQDPSSCHSSNPEFRQLYRYNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKYIKKESSSEISQKAQSRHCVDSNNSSIQNGKYMLNHSLVSCQINNGSLSPERPIGETSFSVPLHPTKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV"
    }, 
    "uniprot_id": "A0A0G2K1Z1_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Lysine (K)-specific demethylase 7A"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "Kdm7a"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                    "id": "A0A0G2K1Z1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Lysine (K)-specific demethylase 7A."
    }, 
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1/publications", 
                    "id": "A0A0G2K1Z1", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", 
            "date": "2012", 
            "pmid": "22673903"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1#A0A0G2K1Z1-1", 
            "isoform_ac": "A0A0G2K1Z1-1", 
            "locus": {
                "end_pos": 66922016, 
                "start_pos": 66955732, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000084282", 
                        "id": "ENSRNOT00000084282", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072042", 
                        "id": "ENSRNOP00000072042", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K1Z1-1|A0A0G2K1Z1_RAT Isoform 1 of Lysine (K)-specific demethylase 7A  OS=Rattus norvegicus OX=10116 GN=Kdm7a PE=1 SV=1 CANONICAL=A0A0G2K1Z1-1", 
                "length": 867, 
                "sequence": "EHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHRHDYTEADDGSKPVQAGTRAFVKELRSRVFPSADEVIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGYNNGILVSGQDCYQQRGRAKHLTGAGLQFKVFEIKNDHGAPALFFFFFFSVFCSFIARSSLHSLTELKEDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPSVCPVSRPSNDASPPGHSRRKMRRLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDILSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFADRSLYTADSENEEDKKPTKKANVKTEQSSGREAAESDGSPKPLNRIFPSVKSELRSRPSEYSDVSDSEDSGPDCTAVKINFATEESESSGDEKKHEITSNFKEESDVVRNLLQKSQKPSRNEIPVKRECPTSTSTEEEAIQGMLSMAGLHYSTCLQSTDCSGEKNSLQDPSSCHSSNPEFRQLYRYNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKYIKKESSSEISQKAQSRHCVDSNNSSIQNGKYMLNHSLVSCQINNGSLSPERPIGETSFSVPLHPTKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3214842", 
            "resource": "Reactome", 
            "id": "R-RNO-3214842", 
            "name": "HDMs demethylate histones"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6ZMT4-1", 
            "protein_name": "Lysine-specific demethylase 7A; 1.14.11.-; JmjC domain-containing histone demethylation protein 1D; Lysine-specific demethylase 7.", 
            "sequence": {
                "length": 941, 
                "sequence": "MAGAAAAVAAGAAAGAAAAAVSVAAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHRHDYTEIDDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKELREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPIVCPVSRSSNEATSPYHSRRKMRKLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDILSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQPFADQSLYTADSENEEDKRRTKKAKMKIEESSGVEGVEHEESQKPLNGFFTRVKSELRSRSSGYSDISESEDSGPECTALKSIFTTEESESSGDEKKQEITSNFKEESNVMRNFLQKSQKPSRSEIPIKRECPTSTSTEEEAIQGMLSMAGLHYSTCLQRQIQSTDCSGERNSLQDPSSCHGSNHEVRQLYRYDKPVECGYHVKTEDPDLRTSSWIKQFDTSRFHPQDLSRSQKCIRKEGSSEISQRVQSRNYVDSSGSSLQNGKYMQNSNLTSGACQISNGSLSPERPVGETSFSVPLHPTKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2K1Z1/", 
                    "id": "A0A0G2K1Z1", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q3UWM4-1", 
            "protein_name": "Lysine-specific demethylase 7A; 1.14.11.-; JmjC domain-containing histone demethylation protein 1D; Lysine-specific demethylase 7.", 
            "sequence": {
                "length": 940, 
                "sequence": "MAGAAAAVAAGAAAGAAAAAGSVSAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPDCAALHGSSLMKKRRNWHRHDYTEVDDGSKPVQAGTRAFVKELRSRVFPSADEIIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPDRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKELKEDGFQPQSYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENGKPVKSQGIPSVCPVSRPSNEASPPYHSRRKMRKLRDHNVRTPSNLDILELHTREVLKRLEMCPWEEDLLSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFADRSLYTADSENEEDKKPTQNANMKTEQSSGREEAESQGSPKPLNRIFTSVRSELRSRPSEYSDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRNLLQKSQKPSRQEIPVKRECPTSTSTEEEAIQGMLSMAGLHYSSCLQRQIQSTDCSGEKNSLQDPSSCHGSNPEFRQLYRCNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKHIKKESSSEINQKAQSRHCVDSNSSSIQNGKYTLNPSLVSCQISNGSLSPERPIGETSFSMPLHPTKRPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2K1Z1/", 
                    "id": "A0A0G2K1Z1", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "histone demethylase activity (H4-K20 specific)", 
                        "id": "GO:0035575"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051864", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "histone demethylase activity (H3-K36 specific)", 
                        "id": "GO:0051864"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "iron ion binding", 
                        "id": "GO:0005506"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "zinc ion binding", 
                        "id": "GO:0008270"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035064", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "methylated histone binding", 
                        "id": "GO:0035064"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071558", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "histone demethylase activity (H3-K27 specific)", 
                        "id": "GO:0071558"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "histone demethylase activity (H3-K9 specific)", 
                        "id": "GO:0032454"
                    }
                ], 
                "total": 7, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoplasm", 
                        "id": "GO:0005654"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleolus", 
                        "id": "GO:0005730"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
                                "id": "A0A0G2K1Z1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of transcription, DNA-templated", 
                        "id": "GO:0045893"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 779, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 777
        }, 
        {
            "end_pos": 780, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 778
        }, 
        {
            "end_pos": 791, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 789
        }, 
        {
            "end_pos": 801, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 799
        }
    ], 
    "crossref": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3214842", 
            "id": "R-RNO-3214842", 
            "database": "Reactome"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000052445", 
            "id": "ENSRNOG00000052445", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/SNVMRNF/", 
            "id": "SNVMRNF", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", 
            "id": "IPR003347", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR041070", 
            "id": "IPR041070", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF17811", 
            "id": "PF17811", 
            "database": "Pfam"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2K1Z1", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 98439.0, 
        "chemical_mass": 98439.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K1Z1", 
            "name": "Kdm7a.", 
            "locus": {
                "end_pos": 66922013, 
                "start_pos": 66955732, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000052445", 
                        "id": "ENSRNOG00000052445", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}