{ "uniprot_canonical_ac": "A0A0G2K160-1", "sequence": { "header": "tr|A0A0G2K160-1|A0A0G2K160_RAT Isoform 1 of AT hook-containing transcription factor 1 OS=Rattus norvegicus OX=10116 GN=Ahctf1 PE=1 SV=1 CANONICAL=A0A0G2K160-1", "length": 2312, "sequence": "MAAEWSLRASLPRPWAGSSPSGTSLTRDPEPSRCSGAMETFVGRSPRTTAGAPSFSCVGVCSTWSCAGLGGSMQDLTAQVTSDLLQFPEVTIEALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEADGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRESVMREGRHLCFQLVSPSGVAISTLSYINRTNQLAVGFADGYLALWNMKSMKREYYTQLEGGRVPVYAVVFQEPENDPRNCCYLWAVQSTQESEGDVVSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLSGGMFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQGEPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLESVVSRTSPHHILDILVHERSLSRGVPPSYPPPEQFFNPSTFNFDATCLLNSGVIHVTCTGFQKETLTFLKKSGPTLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRTWIIEEQPNSAANLRFVLEWTWNKVILTKEDFDRLCVPLFDGSCRFIDPQTIQSIQQCHLLLSNLSTVLSCFAMEAQGITERGLVDLNNKHMVTQLICQYAQMVLWFCHSGLLPEGLDDTLQLSRLRYNYPVIQNYYTSRRQKCERSPRGKWSRDCLLIDGLVSQLGDEVEKLWKRDEGGTGKYPPASIHALLDIYLLDNISEASKHAITIYLLLDIMYSFPNKTDTPIESFPTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEHKQALRYLQTMKPTVSSSSDVLLHLSVLLFNRCMVEAWNLLRQNSNTVNIEELLKHAYEVCQEMGLMEDLLKLPFTNTEQECLVNFLQSSSSVQNHEFLLVHHLQRANYISALKLNQTLKNNLTSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFQEVSRPKPLSAFPKKALTGTVITRSTFISNVLSKIGEVWASHEPRNGISLFNSPKTEQPSPVVHSFPHPELPEAFVGTPISNPSQRISRLLDLVVHPIPQPSQRLEFIQQSPTRSPLCLLSSSLPLSSQLKRPHQQASRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILRSGLRTTSLASPSQSPGRSLTPPFRLKETRISFMEEGMNTHWTDTATDDRNAKAFVSTSFHKCGLPAETEWMKTNDKNTYFPLDVPAKVPQKVVAESLDTHSPRSLEKLDVSKDSTVSSRSDQTLEYHDAPSPEDLEGGVFVSPKPASSSTELTTNSMVQTEKDNDKNLFKSEGTPSAMEKQIGTIEASVEAFSEFSHLDPVERAEASLGVSSVREGETSTSKSKTSVLDGIVSIESRTSIPIADHNEFVANKVEDVESSESTTSKCPVTSERSLDKELTLNLKGDEMEAVVPKESVGLPEERPQTSAGPSDTQEIHLIGCEKLEVQNSEEVAKSLSFPELCPLGAHRPQYNFDVIEQQFRDLPDDKDSAECDVAEVDGELFVAQSNFSLILEGEEGEVEASDSNVLPKVTNIATKEKPVSCEEPDNEGHVTDLPSAVTGDQESHKVETLPYVPEPVKVAIAENLLDVIKDTRSKEATHVAAVEDVDEDRAVMIPKAAHPSRLTNSTPKTVKERRAETVSASQGDDSIAPRTLTRRQRALSLNVTSEQEPSAAATPQKKTRKVKETREFSESTCSDVKVAPENQLTAPSPSPSRRGRKKKDLGQGPLATSGAVEEPQATPERLRLRVQPPEPAAEETPSRAKAKLSSARKGTPRRLRKSIEDGPSADIVNEVRGRKAAGHGRTVRELRSASVEDTQKMEYEQDEERGDQQLPLKRKRVREREDSVSGVTEEPKLDSSQLTLQVGLDVPATPRKRGRRPKRVVPLGADGTTPGKEQTSPQKEGPVVRRSTRNTPARNVSTLEKPILVPNKEAATVMTSKKKPTKKSADGSPKGPFPAVSDLADEAAHRESTDQGVLTSAAFTTPSWSTRTRSRRTMLLTDISEPQTEPLLSSPSLKVPKKETKAKNMEAAAQLKELVSDISSRFVVSPPALRTRQKSTSNASKLLGELESNPKPVEIIEQKPKRSRTVKTKVSRNTGKGSSWSPPPIEIKLISPLASPVDEIKVSKPRKTAEVAGKTLGRGRKKPSSFPKQILRRKML" }, "uniprot_id": "A0A0G2K160_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "protein ELYS isoform X1" ], "uniprotkb": [ "AT hook-containing transcription factor 1" ] }, "gene": { "refseq": [ "Ahctf1", "ELYS", "RGD1561291" ], "uniprotkb": [ "Ahctf1", "ELYS", "RGD1561291" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "AT hook-containing transcription factor 1." }, "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160/publications", "id": "A0A0G2K160", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012", "pmid": "22673903" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160#A0A0G2K160-1", "isoform_ac": "A0A0G2K160-1", "locus": { "end_pos": 98024968, "start_pos": 98078457, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000078034", "id": "ENSRNOT00000078034", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000071711", "id": "ENSRNOP00000071711", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K160-1|A0A0G2K160_RAT Isoform 1 of AT hook-containing transcription factor 1 OS=Rattus norvegicus OX=10116 GN=Ahctf1 PE=1 SV=1 CANONICAL=A0A0G2K160-1", "length": 2312, "sequence": "MAAEWSLRASLPRPWAGSSPSGTSLTRDPEPSRCSGAMETFVGRSPRTTAGAPSFSCVGVCSTWSCAGLGGSMQDLTAQVTSDLLQFPEVTIEALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEADGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRESVMREGRHLCFQLVSPSGVAISTLSYINRTNQLAVGFADGYLALWNMKSMKREYYTQLEGGRVPVYAVVFQEPENDPRNCCYLWAVQSTQESEGDVVSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLSGGMFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQGEPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLESVVSRTSPHHILDILVHERSLSRGVPPSYPPPEQFFNPSTFNFDATCLLNSGVIHVTCTGFQKETLTFLKKSGPTLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRTWIIEEQPNSAANLRFVLEWTWNKVILTKEDFDRLCVPLFDGSCRFIDPQTIQSIQQCHLLLSNLSTVLSCFAMEAQGITERGLVDLNNKHMVTQLICQYAQMVLWFCHSGLLPEGLDDTLQLSRLRYNYPVIQNYYTSRRQKCERSPRGKWSRDCLLIDGLVSQLGDEVEKLWKRDEGGTGKYPPASIHALLDIYLLDNISEASKHAITIYLLLDIMYSFPNKTDTPIESFPTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEHKQALRYLQTMKPTVSSSSDVLLHLSVLLFNRCMVEAWNLLRQNSNTVNIEELLKHAYEVCQEMGLMEDLLKLPFTNTEQECLVNFLQSSSSVQNHEFLLVHHLQRANYISALKLNQTLKNNLTSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFQEVSRPKPLSAFPKKALTGTVITRSTFISNVLSKIGEVWASHEPRNGISLFNSPKTEQPSPVVHSFPHPELPEAFVGTPISNPSQRISRLLDLVVHPIPQPSQRLEFIQQSPTRSPLCLLSSSLPLSSQLKRPHQQASRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILRSGLRTTSLASPSQSPGRSLTPPFRLKETRISFMEEGMNTHWTDTATDDRNAKAFVSTSFHKCGLPAETEWMKTNDKNTYFPLDVPAKVPQKVVAESLDTHSPRSLEKLDVSKDSTVSSRSDQTLEYHDAPSPEDLEGGVFVSPKPASSSTELTTNSMVQTEKDNDKNLFKSEGTPSAMEKQIGTIEASVEAFSEFSHLDPVERAEASLGVSSVREGETSTSKSKTSVLDGIVSIESRTSIPIADHNEFVANKVEDVESSESTTSKCPVTSERSLDKELTLNLKGDEMEAVVPKESVGLPEERPQTSAGPSDTQEIHLIGCEKLEVQNSEEVAKSLSFPELCPLGAHRPQYNFDVIEQQFRDLPDDKDSAECDVAEVDGELFVAQSNFSLILEGEEGEVEASDSNVLPKVTNIATKEKPVSCEEPDNEGHVTDLPSAVTGDQESHKVETLPYVPEPVKVAIAENLLDVIKDTRSKEATHVAAVEDVDEDRAVMIPKAAHPSRLTNSTPKTVKERRAETVSASQGDDSIAPRTLTRRQRALSLNVTSEQEPSAAATPQKKTRKVKETREFSESTCSDVKVAPENQLTAPSPSPSRRGRKKKDLGQGPLATSGAVEEPQATPERLRLRVQPPEPAAEETPSRAKAKLSSARKGTPRRLRKSIEDGPSADIVNEVRGRKAAGHGRTVRELRSASVEDTQKMEYEQDEERGDQQLPLKRKRVREREDSVSGVTEEPKLDSSQLTLQVGLDVPATPRKRGRRPKRVVPLGADGTTPGKEQTSPQKEGPVVRRSTRNTPARNVSTLEKPILVPNKEAATVMTSKKKPTKKSADGSPKGPFPAVSDLADEAAHRESTDQGVLTSAAFTTPSWSTRTRSRRTMLLTDISEPQTEPLLSSPSLKVPKKETKAKNMEAAAQLKELVSDISSRFVVSPPALRTRQKSTSNASKLLGELESNPKPVEIIEQKPKRSRTVKTKVSRNTGKGSSWSPPPIEIKLISPLASPVDEIKVSKPRKTAEVAGKTLGRGRKKPSSFPKQILRRKML" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K160#D3ZZZ0-1", "isoform_ac": "D3ZZZ0-1", "locus": { "end_pos": 98024968, "start_pos": 98075066, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000035875", "id": "ENSRNOT00000035875", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000037261", "id": "ENSRNOP00000037261", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3ZZZ0-1|A0A0G2K160_RAT Computationally mapped isoform of AT hook-containing transcription factor 1 OS=Rattus norvegicus OX=10116 GN=Ahctf1 PE=1 SV=1 CANONICAL=A0A0G2K160-1", "length": 2240, "sequence": "MQDLTAQVTSDLLQFPEVTIEALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEADGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRESVMREGRHLCFQLVSPSGVAISTLSYINRTNQLAVGFADGYLALWNMKSMKREYYTQLEGGRVPVYAVVFQEPENDPRNCCYLWAVQSTQESEGDVVSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLSGGMFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQGEPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLESVVSRTSPHHILDILVHERSLSRGVPPSYPPPEQFFNPSTFNFDATCLLNSGVIHVTCTGFQKETLTFLKKSGPTLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRTWIIEEQPNSAANLRFVLEWTWNKVILTKEDFDRLCVPLFDGSCRFIDPQTIQSIQQCHLLLSNLSTVLSCFAMEAQGITERGLVDLNNKHMVTQLICQYAQMVLWFCHSGLLPEGLDDTLQLSRLRYNYPVIQNYYTSRRQKCERSPRGKWSRDCLLIDGLVSQLGDEVEKLWKRDEGGTGKYPPASIHALLDIYLLDNISEASKHAITIYLLLDIMYSFPNKTDTPIESFPTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEHKQALRYLQTMKPTVSSSSDVLLHLSVLLFNRCMVEAWNLLRQNSNTVNIEELLKHAYEVCQEMGLMEDLLKLPFTNTEQECLVNFLQSSSSVQNHEFLLVHHLQRANYISALKLNQTLKNNLTSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFQEVSRPKPLSAFPKKALTGTVITRSTFISNVLSKIGEVWASHEPRNGISLFNSPKTEQPSPVVHSFPHPELPEAFVGTPISNPSQRISRLLDLVVHPIPQPSQRLEFIQQSPTRSPLCLLSSSLPLSSQLKRPHQQASRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILRSGLRTTSLASPSQSPGRSLTPPFRLKETRISFMEEGMNTHWTDTATDDRNAKAFVSTSFHKCGLPAETEWMKTNDKNTYFPLDVPAKVPQKVVAESLDTHSPRSLEKLDVSKDSTVSSRSDQTLEYHDAPSPEDLEGGVFVSPKPASSSTELTTNSMVQTEKDNDKNLFKSEGTPSAMEKQIGTIEASVEAFSEFSHLDPVERAEASLGVSSVREGETSTSKSKTSVLDGIVSIESRTSIPIADHNEFVANKVEDVESSESTTSKCPVTSERSLDKELTLNLKGDEMEAVVPKESVGLPEERPQTSAGPSDTQEIHLIGCEKLEVQNSEEVAKSLSFPELCPLGAHRPQYNFDVIEQQFRDLPDDKDSAECDVAEVDGELFVAQSNFSLILEGEEGEVEASDSNVLPKVTNIATKEKPVSCEEPDNEGHVTDLPSAVTGDQESHKVETLPYVPEPVKVAIAENLLDVIKDTRSKEATHVAAVEDVDEDRAVMIPKAAHPSRLTNSTPKTVKERRAETVSASQGDDSIAPRTLTRRQRALSLNVTSEQEPSAAATPQKKTRKVKETREFSESTCSDVKVAPENQLTAPSPSPSRRGRKKKDLGQGPLATSGAVEEPQATPERLRLRVQPPEPAAEETPSRAKAKLSSARKGTPRRLRKSIEDGPSADIVNEVRGRKAAGHGRTVRELRSASVEDTQKMEYEQDEERGDQQLPLKRKRVREREDSVSGVTEEPKLDSSQLTLQVGLDVPATPRKRGRRPKRVVPLGADGTTPGKEQTSPQKEGPVVRRSTRNTPARNVSTLEKPILVPNKEAATVMTSKKKPTKKSADGSPKGPFPAVSDLADEAAHRESTDQGVLTSAAFTTPSWSTRTRSRRTMLLTDISEPQTEPLLSSPSLKVPKKETKAKNMEAAAQLKELVSDISSRFVVSPPALRTRQKSTSNASKLLGELESNPKPVEIIEQKPKRSRTVKTKVSRNTGKGSSWSPPPIEIKLISPLASPVDEIKVSKPRKTAEVAGKTLGRGRKKPSSFPKQILRRKML" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-141430", "resource": "Reactome", "id": "R-RNO-141430", "name": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-141444", "resource": "Reactome", "id": "R-RNO-141444", "name": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2500257", "resource": "Reactome", "id": "R-RNO-2500257", "name": "Resolution of Sister Chromatid Cohesion" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2467813", "resource": "Reactome", "id": "R-RNO-2467813", "name": "Separation of Sister Chromatids" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-68877", "resource": "Reactome", "id": "R-RNO-68877", "name": "Mitotic Prometaphase" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5663220", "resource": "Reactome", "id": "R-RNO-5663220", "name": "RHO GTPases Activate Formins" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q8CJF7-1", "protein_name": "Protein ELYS; Protein MEL-28; Embryonic large molecule derived from yolk sac; Putative AT-hook-containing transcription factor 1.", "sequence": { "length": 2243, "sequence": "MQDLTAQVTSDLLHFPEVTIEALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSLTGERLSAYRFSGVNEQPPVVLAVKEFSWHKRTGLLIGLEEADGSVLCLYDLGISRVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLIDLCLDDLSCSQNEVEASDLEVITGIPAEVPHIRERVMREGRHLCFQLVSPLGVAISTLSYINRTNQLAVGFSDGYLALWNMKSMKREYYTQLEGGRVPVHAVAFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGDRKCLASGQILYEGLEYCEERYTLDLAGGTFPLRGQTSNTKLLGCQSIERFPSHGDREESMREALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGESLHNCSYFALWSLDSVVSRTSPHHILDILVHERSLNRGVPPSYPPPEQFFNPSTFNFDATCLLDSGVIHVTCAGFQKETLTFLKKSGPTLNEVIPDSYNRCLVAGLLSPRLIDIQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRTWIIEEQPNSAANLRFVLEWTWNKVVLTKEEFDRLCVPLFDGSCRFIDPQTIQSIQQCHLLLSNLSTVLSCFAMEAQGITERGLVDLSNKHMVTQLLCQYAHMVLWFCHSGLLPEGLDDALQLSRLRYNYPVIQNYYTSRRQKSERSPRGKWNHDCLMIDGLVSQLGDEVEKLWKRDEGGTGRYPPASIHALLDIYLLDNITEASKHAITIYLLLDIMYSFPNKTDTPIESFPTAFAISWGQVKLVQGFWLLDHNDYENGLDLLFHPVTAKPASWQHSKIIEAFMSQGEHKQALRYLQTMKPTVSSSNEVILHLTVLLFNRCMVEAWNLLRQNSNRVNIEELLKHAYEVCQEMGLMEDLLKLPFTNTEQECLVKFLQSSTSVENHEFLLVHHLQRANYISALKLNQILKNNLMSDRDPRLRERSVTRNSILDQYGKILPRVQRKLAVERAKPYHLSTSSVFHEVSRPKPLSAFPKKAITGTVLTRSTFISNVLSKIGEVWASHEPRNGVSLFNSPKTEQPSPVVHSFPHPELPEAFVGTPISNTSQRISRLLDLVVHPVPQPSQCLEFIQQSPTRSPLCLLSSSLPLSSQFKRPHQNTSRPSELLLLETPLIVKKAKSLALSATSSGFAEFTPPSILRSGFRTTPLASPSLSPGRSLTPPFRVKETRISFMEEGMNTHWTDRATDDRNTKAFVSTSFHKCGLPAETEWMKTSDKNTYFPLDVPAKGPQKVVAESLATHSGRLEKLDVSKEDSTASTRSDQTSLEYHDAPSPEDLEGAVFVSPKPASSSTELTTNSTLQTERDNDKDAFKSEGAPSPVKKQIGTGDAAVEAFSELSRLDPVERAEASFAVSSVCEGETSTSNSKTSVLDGIVPIESRTSILTADHKESVANTVADVESSGSTSSKCPVTSERSLGQKLTLNLKEDEIEAHVPKENVGLPEESPRISAAPSDTHEIHLIGCENLEVQNSEEEAKNLSFDELYPLGAEKLEYNLSTIEQQFCDLPDDKDSAECDAAEVDGELFVAQSNFTLILEGEEGEAEASDSAAPNMLPKATKEKPVCHREPHNQERVTDLPSAVTADQESHKVETLPYVPEPVKVAIAENLLDVIKDTRSKEATPVAAGEAGDEDGAVIVSKAAHSSRLTNSTPKTVKEPHAETVNTSQNDDMVSSRTLTRRQHALSLNVTSEQEPSAVATPKKRTRKIKETPESSERTCSDLKVAPENQLTAQSPPAPRRGKKKDVSQGTLPSSGAVEPEPEPQGTPGRLRLRTQPPEPAAEETPSRTKVRLSSVRKGTPRRLKKSVENGQSTEILDDLKGSEAASHDGTVTELRNANLEDTQNMEYKQDEHSDQQLPLKRKRVREREVSVSSVTEEPKLDSSQLPLQTGLDVPATPRKRGRPRKVVPLEADGGTTGKEQTSPQKKDVPVVRRSTRNTPARNVSTLEKSVLVPNKEAALVVTSKRRPTKKSAEESSKDPSAAVSDLAGGAAHTESADRRDGLLAAAALTPSAQGTRTRSRRTMLLTDISEPKTEPLFPPPSVKVPKKKSKAENMEAAAQLKELVSDLSSQFVVSPPALRTRQKSISNTSKLLGELESDPKPLEIIEQKPKRSRTVKTRASRNTGKGSSWSPPPVEIKLVSPLASPVDEIKTGKPRKTAEIAGKTLGRGRKKPSSFPKQILRRKML" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A0G2K160/", "id": "A0A0G2K160", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/9142", "id": "9142", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "Q8WYP5-1", "protein_name": "Protein ELYS; Protein MEL-28; Embryonic large molecule derived from yolk sac; Putative AT-hook-containing transcription factor 1.", "sequence": { "length": 2266, "sequence": "MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSITGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAVVLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQNEVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFSDGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLSLHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKFRSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGEYLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDATCLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLSQEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDRLCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVSHLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNPDCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLLLDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLSWQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHCNRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQRANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYHLSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNSSKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSMKSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQSILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKKCAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/9142", "id": "9142", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006250448.1", "ac": "XP_006250448.1", "name": "protein ELYS isoform X1.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "DNA-binding transcription factor activity", "id": "GO:0003700" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "nuclear pore outer ring", "id": "GO:0031080" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "nuclear membrane", "id": "GO:0031965" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "nuclear matrix", "id": "GO:0016363" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "chromatin", "id": "GO:0000785" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000777", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "condensed chromosome kinetochore", "id": "GO:0000777" } ], "total": 6, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "regulation of cytokinesis", "id": "GO:0032465" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "id": "A0A0G2K160", "database": "UniProtKB" } ], "name": "nuclear pore complex assembly", "id": "GO:0051292" } ], "total": 2, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 304, "annotation": "n_glycosylation_sequon", "start_pos": 302 }, { "end_pos": 498, "annotation": "n_glycosylation_sequon", "start_pos": 496 }, { "end_pos": 704, "annotation": "n_glycosylation_sequon", "start_pos": 702 }, { "end_pos": 840, "annotation": "n_glycosylation_sequon", "start_pos": 838 }, { "end_pos": 863, "annotation": "n_glycosylation_sequon", "start_pos": 861 }, { "end_pos": 1045, "annotation": "n_glycosylation_sequon", "start_pos": 1043 }, { "end_pos": 1051, "annotation": "n_glycosylation_sequon", "start_pos": 1049 }, { "end_pos": 1664, "annotation": "n_glycosylation_sequon", "start_pos": 1662 }, { "end_pos": 1782, "annotation": "n_glycosylation_sequon", "start_pos": 1780 }, { "end_pos": 1820, "annotation": "n_glycosylation_sequon", "start_pos": 1818 }, { "end_pos": 2073, "annotation": "n_glycosylation_sequon", "start_pos": 2071 }, { "end_pos": 2216, "annotation": "n_glycosylation_sequon", "start_pos": 2214 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006250448.1", "id": "XP_006250448.1", "database": "RefSeq" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-141430", "id": "R-RNO-141430", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-141444", "id": "R-RNO-141444", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2500257", "id": "R-RNO-2500257", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2467813", "id": "R-RNO-2467813", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-68877", "id": "R-RNO-68877", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5663220", "id": "R-RNO-5663220", "database": "Reactome" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000023541", "id": "ENSRNOG00000023541", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/MVTQLIC/", "id": "MVTQLIC", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR032040", "id": "IPR032040", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR025151", "id": "IPR025151", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF16687", "id": "PF16687", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF13934", "id": "PF13934", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/360886", "id": "360886", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1561291", "id": "1561291", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K160", "disease": [], "mass": { "monoisotopic_mass": 255188.0, "chemical_mass": 255188.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K160", "name": "Ahctf1; ELYS; RGD1561291.", "locus": { "end_pos": 98023430, "start_pos": 98078946, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000023541", "id": "ENSRNOG00000023541", "database": "Ensembl Gene" } ] } } ] }