{ "uniprot_canonical_ac": "A0A0G2K0P5-1", "sequence": { "header": "tr|A0A0G2K0P5-1|A0A0G2K0P5_RAT Isoform 1 of Thyroid hormone receptor interactor 4 OS=Rattus norvegicus OX=10116 GN=Trip4 PE=1 SV=1 CANONICAL=A0A0G2K0P5-1", "length": 682, "sequence": "MLRPLLSNSVGLLSGSAFKYPPPPQPLFVDYCWSCPSVPKNSQALFFPIRVKQTRKLGEAAQRSRAVRTYGTLVNEVGVAKGTSPAQDEKLLQPSWFRSGKMAVAGAASGEPLVHWCTQQLRKTFALDVSEEIIQYVLSIESAEEIRDYVTDLLQGNEGKKGQFIEDLITKWQKKDQECISDSFQQCWKKDESLDGQRSVDQLKRSRRKGRNKQEVPAFPEPDVTVEVKTPLDLAKAQEGNSSVKKKTRFVSLYTREGQDKLAVLLPGRHPCDCLGQKHKLINNCLVCGRIVCEQEGSGPCLFCGSLVCTNEEQDILQRDSNKSQKLLKKLMSGAENSGKVDISTKDHPPHQESRMKSGLEKAVKHKEKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKVERDMLQKREEELRELRHASRLSKKVTIDFAGRKILEDENPLAEYHSRLDETIQAIANGTLNQSLVTSDRSSEEPLGVLVNPNMYQAPPQWVDNTGSAPPKKTSLSVGPRLELSLHPHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVKGIKRVEGRSWYTPHRGRLWIAATGKRPSTQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFQEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV" }, "uniprot_id": "A0A0G2K0P5_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [], "uniprotkb": [ "Thyroid hormone receptor interactor 4" ] }, "gene": { "refseq": [], "uniprotkb": [ "Trip4" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Thyroid hormone receptor interactor 4." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5#A0A0G2K0P5-1", "isoform_ac": "A0A0G2K0P5-1", "locus": { "end_pos": 71373206, "start_pos": 71533263, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000085745", "id": "ENSRNOT00000085745", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000071531", "id": "ENSRNOP00000071531", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K0P5-1|A0A0G2K0P5_RAT Isoform 1 of Thyroid hormone receptor interactor 4 OS=Rattus norvegicus OX=10116 GN=Trip4 PE=1 SV=1 CANONICAL=A0A0G2K0P5-1", "length": 682, "sequence": "MLRPLLSNSVGLLSGSAFKYPPPPQPLFVDYCWSCPSVPKNSQALFFPIRVKQTRKLGEAAQRSRAVRTYGTLVNEVGVAKGTSPAQDEKLLQPSWFRSGKMAVAGAASGEPLVHWCTQQLRKTFALDVSEEIIQYVLSIESAEEIRDYVTDLLQGNEGKKGQFIEDLITKWQKKDQECISDSFQQCWKKDESLDGQRSVDQLKRSRRKGRNKQEVPAFPEPDVTVEVKTPLDLAKAQEGNSSVKKKTRFVSLYTREGQDKLAVLLPGRHPCDCLGQKHKLINNCLVCGRIVCEQEGSGPCLFCGSLVCTNEEQDILQRDSNKSQKLLKKLMSGAENSGKVDISTKDHPPHQESRMKSGLEKAVKHKEKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKVERDMLQKREEELRELRHASRLSKKVTIDFAGRKILEDENPLAEYHSRLDETIQAIANGTLNQSLVTSDRSSEEPLGVLVNPNMYQAPPQWVDNTGSAPPKKTSLSVGPRLELSLHPHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVKGIKRVEGRSWYTPHRGRLWIAATGKRPSTQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFQEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5#B5DEP5-1", "isoform_ac": "B5DEP5-1", "locus": { "end_pos": 71373206, "start_pos": 71509566, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000021863", "id": "ENSRNOT00000021863", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000021863", "id": "ENSRNOP00000021863", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|B5DEP5-1|A0A0G2K0P5_RAT Computationally mapped isoform of Thyroid hormone receptor interactor 4 OS=Rattus norvegicus OX=10116 GN=Trip4 PE=1 SV=1 CANONICAL=A0A0G2K0P5-1", "length": 581, "sequence": "MAVAGAASGEPLVHWCTQQLRKTFALDVSEEIIQYVLSIESAEEIRDYVTDLLQGNEGKKGQFIEDLITKWQKKDQECISDSFQQCWKKDESLDGQRSVDQLKRSRRKGRNKQEVPAFPEPDVTVEVKTPLDLAKAQEGNSSVKKKTRFVSLYTREGQDKLAVLLPGRHPCDCLGQKHKLINNCLVCGRIVCEQEGSGPCLFCGSLVCTNEEQDILQRDSNKSQKLLKKLMSGAENSGKVDISTKDHPPHQESRMKSGLEKAVKHKEKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKVERDMLQKREEELRELRHASRLSKKVTIDFAGRKILEDENPLAEYHSRLDETIQAIANGTLNQSLVTSDRSSEEPLGVLVNPNMYQAPPQWVDNTGSAPPKKTSLSVGPRLELSLHPHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVKGIKRVEGRSWYTPHRGRLWIAATGKRPSTQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFQEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV" } } ], "pathway": [], "function": [], "orthologs": [], "refseq": { "url": "", "ac": "", "name": "", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "transcription coactivator activity", "id": "GO:0003713" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002020", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "protease binding", "id": "GO:0002020" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "zinc ion binding", "id": "GO:0008270" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "protein kinase binding", "id": "GO:0019901" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "estrogen receptor binding", "id": "GO:0030331" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "histone acetyltransferase binding", "id": "GO:0035035" } ], "total": 7, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "centrosome", "id": "GO:0005813" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "neuromuscular junction", "id": "GO:0031594" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "nuclear body", "id": "GO:0016604" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099053", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "activating signal cointegrator 1 complex", "id": "GO:0099053" } ], "total": 6, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "positive regulation of transcription, DNA-templated", "id": "GO:0045893" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901998", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "toxin transport", "id": "GO:1901998" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030520", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "intracellular estrogen receptor signaling pathway", "id": "GO:0030520" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045661", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "id": "A0A0G2K0P5", "database": "UniProtKB" } ], "name": "regulation of myoblast differentiation", "id": "GO:0045661" } ], "total": 4, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 243, "annotation": "n_glycosylation_sequon", "start_pos": 241 }, { "end_pos": 324, "annotation": "n_glycosylation_sequon", "start_pos": 322 }, { "end_pos": 461, "annotation": "n_glycosylation_sequon", "start_pos": 459 }, { "end_pos": 465, "annotation": "n_glycosylation_sequon", "start_pos": 463 } ], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000016121", "id": "ENSRNOG00000016121", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/LEFDRTX/", "id": "LEFDRTX", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "id": "IPR015947", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR007374", "id": "IPR007374", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR009349", "id": "IPR009349", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR039128", "id": "IPR039128", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF06221", "id": "PF06221", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF04266", "id": "PF04266", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12963", "id": "PTHR12963", "database": "PANTHER" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306838", "id": "1306838", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K0P5", "disease": [], "mass": { "monoisotopic_mass": 76985.0, "chemical_mass": 76985.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K0P5", "name": "Trip4.", "locus": { "end_pos": 71371370, "start_pos": 71533459, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000016121", "id": "ENSRNOG00000016121", "database": "Ensembl Gene" } ] } } ] }