{ "uniprot_canonical_ac": "A0A0G2K016-1", "sequence": { "header": "tr|A0A0G2K016-1|A0A0G2K016_RAT Isoform 1 of Sad1 and UNC84 domain-containing 1 OS=Rattus norvegicus OX=10116 GN=Sun1 PE=1 SV=1 CANONICAL=A0A0G2K016-1", "length": 915, "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTTTHSQLSQPHRAAGAMGRLCTYTGDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ" }, "uniprot_id": "A0A0G2K016_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "SUN domain-containing protein 1 isoform X3" ], "uniprotkb": [ "Sad1 and UNC84 domain-containing 1", "Unc-84 homolog A (C. elegans), isoform CRA_a" ] }, "gene": { "refseq": [ "Sun1", "Unc84a" ], "uniprotkb": [ "Sun1", "Unc84a", "rCG_42687" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Sad1 and UNC84 domain-containing 1; Unc-84 homolog A (C. elegans), isoform CRA_a." }, "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016/publications", "id": "A0A0G2K016", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012", "pmid": "22673903" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016#A0A0G2K016-1", "isoform_ac": "A0A0G2K016-1", "locus": { "end_pos": 17489802, "start_pos": 17519937, "chromosome": "12", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000089418", "id": "ENSRNOT00000089418", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000071265", "id": "ENSRNOP00000071265", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K016-1|A0A0G2K016_RAT Isoform 1 of Sad1 and UNC84 domain-containing 1 OS=Rattus norvegicus OX=10116 GN=Sun1 PE=1 SV=1 CANONICAL=A0A0G2K016-1", "length": 915, "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRGASFYLDRTLWLAKYTSSSFASFIVQLFQVVLMKLNFESETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTTTHSQLSQPHRAAGAMGRLCTYTGDLLVRALRRTRAAGWSVAEAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K016#Q5U2W0-1", "isoform_ac": "Q5U2W0-1", "locus": { "end_pos": 17489802, "start_pos": 17519937, "chromosome": "12", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000047287", "id": "ENSRNOT00000047287", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000045984", "id": "ENSRNOP00000045984", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Q5U2W0-1|A0A0G2K016_RAT Computationally mapped isoform of Sad1 and UNC84 domain-containing 1 OS=Rattus norvegicus OX=10116 GN=Sun1 PE=1 SV=1 CANONICAL=A0A0G2K016-1", "length": 757, "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLITTTAAYSSGDGQTVDTHISTSRATPAKGRETRTVKQRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAVHGPTSRVYSRDRTLRPRKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGFSLWGQGNFFSLLPMLNWTAMQPAQRVDNPKDMHRPGPLSPSPPLKVDPMASQWPQESDMGQKIASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKDMVGQHLQEIGSIEPPDAKTDFLTLHHDHEVRLSSLEDVLRKLTEKSEAIQKELEETKLRAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLRSSCEQADARIQETVQLMFSEDQPGGSLEWLLQKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAMSQAGISGITEAQAHIIVNNALRLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQGFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ" } } ], "pathway": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q9D666-1", "protein_name": "SUN domain-containing protein 1; unc-84 protein-like 1; Protein unc-84 homolog A.", "sequence": { "length": 913, "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHKLEPVFDSPRMSRRSLRLVTTASYSSGDSQAIDSHISTSRATPAKGRETRTVKQRRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAIHGTTSRVYSRDRTLKPRGVSFYLDRTLWLAKSTSSSFASFIVQLFQVVLMKLNFETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLEIHTATHSQLPQPHRVAGAMGRLCIYTGDLLVQALRRTRAAGWSVAEAVWSVLWLAVSAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGVSLWGQGNFFSLLPVLNWTAMQPTQRVDDSKGMHRPGPLPPSPPPKVDHKASQWPQESDMGQKVASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKNVVGQHLQEMGTIEPPDAKTDFMTFHHDHEVRLSNLEDVLRKLTEKSEAIQKELEETKLKAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLKTSCEQAGARIQETVQLMFSEDQQGGSLEWLLEKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAVNQAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPKDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/11544", "id": "11544", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "O94901-1", "protein_name": "SUN domain-containing protein 1; unc-84 protein-like 1; Protein unc-84 homolog A.", "sequence": { "length": 812, "sequence": "MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/11544", "id": "11544", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249005.1", "ac": "XP_006249005.1", "name": "SUN domain-containing protein 1 isoform X3.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "protein membrane anchor", "id": "GO:0043495" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005521", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "lamin binding", "id": "GO:0005521" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "nuclear envelope", "id": "GO:0005635" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005639", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "integral component of nuclear inner membrane", "id": "GO:0005639" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993" } ], "total": 5, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009612", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "response to mechanical stimulus", "id": "GO:0009612" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "ossification", "id": "GO:0001503" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "nuclear envelope organization", "id": "GO:0006998" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090286", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "cytoskeletal anchoring at nuclear membrane", "id": "GO:0090286" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021817", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration", "id": "GO:0021817" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090292", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "nuclear matrix anchoring at nuclear membrane", "id": "GO:0090292" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070197", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "meiotic attachment of telomere to nuclear envelope", "id": "GO:0070197" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "synapsis", "id": "GO:0007129" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "id": "A0A0G2K016", "database": "UniProtKB" } ], "name": "centrosome localization", "id": "GO:0051642" } ], "total": 9, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 451, "annotation": "n_glycosylation_sequon", "start_pos": 449 }, { "end_pos": 694, "annotation": "n_glycosylation_sequon", "start_pos": 692 }, { "end_pos": 838, "annotation": "n_glycosylation_sequon", "start_pos": 836 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249005.1", "id": "XP_006249005.1", "database": "RefSeq" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000001299", "id": "ENSRNOG00000001299", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/SLQMFHA/", "id": "SLQMFHA", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "id": "IPR008979", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR018539", "id": "IPR018539", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR032680", "id": "IPR032680", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "id": "IPR012919", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR040994", "id": "IPR040994", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF09387", "id": "PF09387", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF07738", "id": "PF07738", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF18580", "id": "PF18580", "database": "Pfam" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF23", "id": "PTHR12911:SF23", "database": "PANTHER" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/360773", "id": "360773", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359142", "id": "1359142", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A0G2K016", "disease": [], "mass": { "monoisotopic_mass": 102401.0, "chemical_mass": 102401.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K016", "name": "Sun1; Unc84a; rCG_42687.", "locus": { "end_pos": 17488487, "start_pos": 17522534, "chromosome": "12", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000001299", "id": "ENSRNOG00000001299", "database": "Ensembl Gene" } ] } } ] }