{
    "uniprot_canonical_ac": "A0A0G2JZ71-1", 
    "sequence": {
        "header": "tr|A0A0G2JZ71-1|A0A0G2JZ71_RAT Isoform 1 of Adenylate kinase 7  OS=Rattus norvegicus OX=10116 GN=Ak7 PE=4 SV=1 CANONICAL=A0A0G2JZ71-1", 
        "length": 724, 
        "sequence": "MAEEEVPATTEKVLKIQRVFINHLDTYSSGNIGKFLANCVAGASLEEIGEEEEEEDETKSAGAATEATTTKVKEGTFQIVGTLAKLESTRPDFAVETYSHGTSREDLLARLLECDVVVYNITENAQQVQEALWAVSALSEEISHFEKRKMFILLSTVMTWARSKPLDPDDSEVPFTEEDYRRRKHHPNFQDHINAEKLVLKFGKNAKKFVTYVVASGLQYGVEGGILHAFFKMAWLGEIPALPVFGDGSNCIPAIHVLDLAGVIQNVIDHVPKLHYLVAVDESVHTLEDLVKCISKNTGPGKIQKVPKENAFLTKDLTQEHLDQLLVNLRMEALFVKENFNIRWAAQTGFVENIGSILKEYKQSRGLLPIKICILGPPAVGKSSISGELVKYYKLHHIKIKDVISEAIAKLEAIVAPKESTEEEEGEEEEEEENVEDAQELLDGIKESMEQNAGRLEDQYVIRFVKEKLKSMPCKNQGYVLDGFPKTYDQAKDLFNQEDEEEEEEVRGKMFPYDKLITPEFVCNLDASDEFLKERVMNLPESVVAGTHYSQDRFLRALSNYRDINTDDETVFNYFDEIEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEVEKKAAEERLAKEAAQTAEREHKEALEMAEKIARWEEWSKRLEEVKREERELLEAQSIPLRNYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYLFKNNPEMQ"
    }, 
    "uniprot_id": "A0A0G2JZ71_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [
                "adenylate kinase 7", 
                "putative adenylate kinase 7"
            ], 
            "uniprotkb": [
                "Adenylate kinase 7"
            ]
        }, 
        "gene": {
            "refseq": [
                "Ak7"
            ], 
            "uniprotkb": [
                "Ak7"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
                    "id": "A0A0G2JZ71", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Adenylate kinase 7."
    }, 
    "publication": [
        {
            "title": "The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/23416111", 
            "journal": "The international journal of biochemistry & cell biology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
                    "id": "NP_001101525.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Amiri M, Conserva F, Panayiotou C, Karlsson A, Solaroli N", 
            "date": "2013", 
            "pmid": "23416111"
        }, 
        {
            "title": "Congenital hydrocephalus in genetically engineered mice.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/21746835", 
            "journal": "Veterinary pathology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
                    "id": "NP_001101525.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Vogel P, Read RW, Hansen GM, Payne BJ, Small D, Sands AT, Zambrowicz BP", 
            "date": "2012", 
            "pmid": "21746835"
        }, 
        {
            "title": "The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/21080915", 
            "journal": "The Biochemical journal", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
                    "id": "NP_001101525.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Panayiotou C, Solaroli N, Xu Y, Johansson M, Karlsson A", 
            "date": "2011", 
            "pmid": "21080915"
        }, 
        {
            "title": "Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/18776131", 
            "journal": "American journal of respiratory cell and molecular biology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
                    "id": "NP_001101525.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Fernandez-Gonzalez A, Kourembanas S, Wyatt TA, Mitsialis SA", 
            "date": "2009", 
            "pmid": "18776131"
        }, 
        {
            "title": "Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/10215863", 
            "journal": "European journal of biochemistry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
                    "id": "NP_001101525.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Van Rompay AR, Johansson M, Karlsson A", 
            "date": "1999", 
            "pmid": "10215863"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71#A0A0G2JZ71-1", 
            "isoform_ac": "A0A0G2JZ71-1", 
            "locus": {
                "end_pos": 129539200, 
                "start_pos": 129606323, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000082522", 
                        "id": "ENSRNOT00000082522", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073263", 
                        "id": "ENSRNOP00000073263", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2JZ71-1|A0A0G2JZ71_RAT Isoform 1 of Adenylate kinase 7  OS=Rattus norvegicus OX=10116 GN=Ak7 PE=4 SV=1 CANONICAL=A0A0G2JZ71-1", 
                "length": 724, 
                "sequence": "MAEEEVPATTEKVLKIQRVFINHLDTYSSGNIGKFLANCVAGASLEEIGEEEEEEDETKSAGAATEATTTKVKEGTFQIVGTLAKLESTRPDFAVETYSHGTSREDLLARLLECDVVVYNITENAQQVQEALWAVSALSEEISHFEKRKMFILLSTVMTWARSKPLDPDDSEVPFTEEDYRRRKHHPNFQDHINAEKLVLKFGKNAKKFVTYVVASGLQYGVEGGILHAFFKMAWLGEIPALPVFGDGSNCIPAIHVLDLAGVIQNVIDHVPKLHYLVAVDESVHTLEDLVKCISKNTGPGKIQKVPKENAFLTKDLTQEHLDQLLVNLRMEALFVKENFNIRWAAQTGFVENIGSILKEYKQSRGLLPIKICILGPPAVGKSSISGELVKYYKLHHIKIKDVISEAIAKLEAIVAPKESTEEEEGEEEEEEENVEDAQELLDGIKESMEQNAGRLEDQYVIRFVKEKLKSMPCKNQGYVLDGFPKTYDQAKDLFNQEDEEEEEEVRGKMFPYDKLITPEFVCNLDASDEFLKERVMNLPESVVAGTHYSQDRFLRALSNYRDINTDDETVFNYFDEIEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEVEKKAAEERLAKEAAQTAEREHKEALEMAEKIARWEEWSKRLEEVKREERELLEAQSIPLRNYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYLFKNNPEMQ"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:314416", 
            "resource": "KEGG Pathway", 
            "id": "rno:314416", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-499943", 
            "resource": "Reactome", 
            "id": "R-RNO-499943", 
            "name": "Interconversion of nucleotide di- and triphosphates"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q96M32-1", 
            "protein_name": "Adenylate kinase 7; AK 7; 2.7.4.6; 2.7.4.3; ATP-AMP transphosphorylase 7.", 
            "sequence": {
                "length": 723, 
                "sequence": "MAEEEETAALTEKVIRTQRVFINLLDSYSSGNIGKFLSNCVVGASLEEITEEEEEEDENKSAMLEASSTKVKEGTFQIVGTLSKPDSPRPDFAVETYSAISREDLLMRLLECDVIIYNITESSQQMEEAIWAVSALSEEVSHFEKRKLFILLSTVMTWARSKALDPEDSEVPFTEEDYRRRKSHPNFLDHINAEKMVLKFGKKARKFAAYVVAAGLQYGAEGGMLHTFFKMAWLGEIPALPVFGDGTNVIPTIHVLDLAGVIQNVIDHVPKPHYLVAVDESVHTLEDIVKCISKNTGPGKIQKIPRENAYLTKDLTQDCLDHLLVNLRMEALFVKENFNIRWAAQTGFVENINTILKEYKQSRGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERELLEAQSIPLRNYLMTYVMPTLIQGLNECCNVRPEDPVDFLAEYLFKNNPEAQ"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/14268", 
                    "id": "14268", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q9D2H2-2", 
            "protein_name": "Adenylate kinase 7; AK 7; 2.7.4.6; 2.7.4.3; ATP-AMP transphosphorylase 7.", 
            "sequence": {
                "length": 614, 
                "sequence": "MECDAVIYNITENVQQVEEALWAVSALNEEISHFEKRKVFILLSTVMTWARSKPLDPDDNEVPFTEEDYRRRKHHPNFLDHINAEKIVLKFGKNAKKFATYVVASGLQYGAEGGILHTFFKMAWLGEVPALPVFGDGTNCIPAIHVVDLAGVIQNIIDHVPKLHYLVAVDEAVHTLEDLVKCISKNTGPGKIQKVPKENAFLTKDLTQEYLDHLLVNLRMEALFVKENFNIRWVAQTGFVENINSILKEYKQSRGLLPIKICILGPPAVGKSSISEELAKYYKLHHIKMKDVIAEAIAKLEAIVAPKDSVEGEEEGEEEEEEENVDDAQELLDGIKESMEQNAGRLEDQYIIRFVKEKLKSMPCRNQGFILDGFPKTYDQAKDLFNQEEEEEEEEIRGKIFPYDKLITPEFVCGLDASDEFLKERVMNLPESVVAGTHYSQDRFLRSLSHYRDINTDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIGKPRNYGLTDEEKAEEEKKAAEERLAKEAAQTAELEHKEAMEMAEKIARWEEWNKRLEEVKREERELLEVQSVPLRNYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYLFKNNPEMQ"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/14268", 
                    "id": "14268", 
                    "database": "MGI"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
        "ac": "NP_001101525.2", 
        "name": "adenylate kinase 7; putative adenylate kinase 7.", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004017", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
                                "id": "A0A0G2JZ71", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "adenylate kinase activity", 
                        "id": "GO:0004017"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
                                "id": "A0A0G2JZ71", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ATP binding", 
                        "id": "GO:0005524"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
                                "id": "A0A0G2JZ71", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoside diphosphate kinase activity", 
                        "id": "GO:0004550"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004127", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
                                "id": "A0A0G2JZ71", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytidylate kinase activity", 
                        "id": "GO:0004127"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009142", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
                                "id": "A0A0G2JZ71", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoside triphosphate biosynthetic process", 
                        "id": "GO:0009142"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 122, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 120
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101525.2", 
            "id": "NP_001101525.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-499943", 
            "id": "R-RNO-499943", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/www_bget?rno:314416", 
            "id": "rno:314416", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000055714", 
            "id": "ENSRNOG00000055714", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/KMFILIS/", 
            "id": "KMFILIS", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01428", 
            "id": "cd01428", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007858", 
            "id": "IPR007858", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR026867", 
            "id": "IPR026867", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", 
            "id": "IPR027417", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", 
            "id": "IPR036291", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000850", 
            "id": "IPR000850", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF05186", 
            "id": "PF05186", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23359", 
            "id": "PTHR23359", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23359:SF105", 
            "id": "PTHR23359:SF105", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/314416", 
            "id": "314416", 
            "database": "GeneID"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309600", 
            "id": "1309600", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2JZ71", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 82441.0, 
        "chemical_mass": 82441.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZ71", 
            "name": "Ak7.", 
            "locus": {
                "end_pos": 129606932, 
                "start_pos": 129538982, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000055714", 
                        "id": "ENSRNOG00000055714", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}