{ "uniprot_canonical_ac": "A0A0G2JV16-1", "sequence": { "header": "tr|A0A0G2JV16-1|A0A0G2JV16_RAT Isoform 1 of Dedicator of cytokinesis 11 OS=Rattus norvegicus OX=10116 GN=Dock11 PE=1 SV=1 CANONICAL=A0A0G2JV16-1", "length": 2086, "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISLSVIGRQLRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFLVNCHDLTFNILGHIGDNAKGPPTNVEPFFITLALFDVKNNCKISADFHVDLNPPSVREMLWGMSTQLANDGNTKGSSPESLIHGIAESRLCYIRQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDLQGSLDLDGKFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDTSALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVTTLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHILHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDFFSFAVDRLTSVDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFVSPTSRGSLATDKEPAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTGENTRQSSSRTSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISFRLVKLYGEKFGTENIKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPITCEQQVNLKPIDVATDEIKDKTAELHKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYSEV" }, "uniprot_id": "A0A0G2JV16_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "dedicator of cytokinesis protein 11 isoform X1" ], "uniprotkb": [ "Dedicator of cytokinesis 11" ] }, "gene": { "refseq": [ "Dock11" ], "uniprotkb": [ "Dock11" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "Dedicator of cytokinesis 11." }, "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16/publications", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012", "pmid": "22673903" } ], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16#A0A0G2JV16-1", "isoform_ac": "A0A0G2JV16-1", "locus": { "end_pos": 122507473, "start_pos": 122690121, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000080517", "id": "ENSRNOT00000080517", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000069314", "id": "ENSRNOP00000069314", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JV16-1|A0A0G2JV16_RAT Isoform 1 of Dedicator of cytokinesis 11 OS=Rattus norvegicus OX=10116 GN=Dock11 PE=1 SV=1 CANONICAL=A0A0G2JV16-1", "length": 2086, "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISLSVIGRQLRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFLVNCHDLTFNILGHIGDNAKGPPTNVEPFFITLALFDVKNNCKISADFHVDLNPPSVREMLWGMSTQLANDGNTKGSSPESLIHGIAESRLCYIRQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDLQGSLDLDGKFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDTSALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVTTLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHILHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDFFSFAVDRLTSVDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFVSPTSRGSLATDKEPAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTGENTRQSSSRTSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISFRLVKLYGEKFGTENIKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPITCEQQVNLKPIDVATDEIKDKTAELHKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYSEV" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16#F1LQ91-1", "isoform_ac": "F1LQ91-1", "locus": { "end_pos": 122507473, "start_pos": 122690121, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000032275", "id": "ENSRNOT00000032275", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000032402", "id": "ENSRNOP00000032402", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F1LQ91-1|A0A0G2JV16_RAT Computationally mapped isoform of Dedicator of cytokinesis 11 OS=Rattus norvegicus OX=10116 GN=Dock11 PE=1 SV=2 CANONICAL=A0A0G2JV16-1", "length": 2073, "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISLSVIGRQLRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFLVNCHDLTFNILGHIGDNAKGPPTNVEPFFITLALFDVKNNCKISADFHVDLNPPSVREMLWGMSTQLANDGNTKGSSPESLIHGIAESRLCYIRQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDLQGSLDLDGKFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDTSALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVTTLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHILHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFVSPTSRGSLATDKEPAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTGENTRQSSSRTSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISFRLVKLYGEKFGTENIKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPITCEQQVNLKPIDVATDEIKDKTAELHKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYSEV" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-983231", "resource": "Reactome", "id": "R-RNO-983231", "name": "Factors involved in megakaryocyte development and platelet production" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q5JSL3-1", "protein_name": "Dedicator of cytokinesis protein 11; Activated Cdc42-associated guanine nucleotide exchange factor; ACG; Zizimin-2.", "sequence": { "length": 2073, "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/70950", "id": "70950", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "A2AF47-1", "protein_name": "Dedicator of cytokinesis protein 11; Activated Cdc42-associated guanine nucleotide exchange factor; ACG; Zizimin-2.", "sequence": { "length": 2073, "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLIMLKKIIQINTDSLVQEKKDTVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFMVNCHDLTFNILGHIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGTSTQLSNDGNAKGFSPESLIHGIAESQLCYIKQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDVQGSLDLDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLSITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVITLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNGNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPSSASRDEFPCGFVSPTNRGSLASDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTSENTRQSSSRSSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKNQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQVNLKPIDVATDEIKDKTAELHKLCSSVDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYAEV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/70950", "id": "70950", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006257515.1", "ac": "XP_006257515.1", "name": "dedicator of cytokinesis protein 11 isoform X1.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005089", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "Rho guanyl-nucleotide exchange factor activity", "id": "GO:0005089" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "positive regulation of GTPase activity", "id": "GO:0043547" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "small GTPase mediated signal transduction", "id": "GO:0007264" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "positive regulation of filopodium assembly", "id": "GO:0051491" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001782", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "B cell homeostasis", "id": "GO:0001782" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002315", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2JV16", "id": "A0A0G2JV16", "database": "UniProtKB" } ], "name": "marginal zone B cell differentiation", "id": "GO:0002315" } ], "total": 5, "name": 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