{
    "uniprot_canonical_ac": "A0A0G2JUG7-1", 
    "sequence": {
        "header": "tr|A0A0G2JUG7-1|A0A0G2JUG7_RAT Isoform 1 of IQ motif and Sec7 domain 1  OS=Rattus norvegicus OX=10116 GN=Iqsec1 PE=1 SV=1 CANONICAL=A0A0G2JUG7-1", 
        "length": 962, 
        "sequence": "MACRRRYLSSLETGSSLSTDRYSVEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGPGPQQRTRRPRLQHSTSVLRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSDRSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFQPSQPPVLCS"
    }, 
    "uniprot_id": "A0A0G2JUG7_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "IQ motif and Sec7 domain 1"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "Iqsec1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
                    "id": "A0A0G2JUG7", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "IQ motif and Sec7 domain 1."
    }, 
    "publication": [
        {
            "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", 
            "journal": "Nat. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7/publications", 
                    "id": "A0A0G2JUG7", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", 
            "date": "2012", 
            "pmid": "22673903"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7#A0A0G2JUG7-1", 
            "isoform_ac": "A0A0G2JUG7-1", 
            "locus": {
                "end_pos": 123307990, 
                "start_pos": 123453277, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000085466", 
                        "id": "ENSRNOT00000085466", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000069092", 
                        "id": "ENSRNOP00000069092", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2JUG7-1|A0A0G2JUG7_RAT Isoform 1 of IQ motif and Sec7 domain 1  OS=Rattus norvegicus OX=10116 GN=Iqsec1 PE=1 SV=1 CANONICAL=A0A0G2JUG7-1", 
                "length": 962, 
                "sequence": "MACRRRYLSSLETGSSLSTDRYSVEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGPGPQQRTRRPRLQHSTSVLRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDPALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSDRSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFQPSQPPVLCS"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005086", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
                                "id": "A0A0G2JUG7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ARF guanyl-nucleotide exchange factor activity", 
                        "id": "GO:0005086"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
                                "id": "A0A0G2JUG7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleolus", 
                        "id": "GO:0005730"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
                                "id": "A0A0G2JUG7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "actin cytoskeleton organization", 
                        "id": "GO:0030036"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
                                "id": "A0A0G2JUG7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of GTPase activity", 
                        "id": "GO:0043547"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
                                "id": "A0A0G2JUG7", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of ARF protein signal transduction", 
                        "id": "GO:0032012"
                    }
                ], 
                "total": 3, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 453, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 451
        }, 
        {
            "end_pos": 471, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 469
        }, 
        {
            "end_pos": 475, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 473
        }, 
        {
            "end_pos": 481, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 479
        }, 
        {
            "end_pos": 485, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 483
        }, 
        {
            "end_pos": 900, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 898
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000060350", 
            "id": "ENSRNOG00000060350", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/VQSECSD/", 
            "id": "VQSECSD", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13318", 
            "id": "cd13318", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", 
            "id": "cd00171", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033742", 
            "id": "IPR033742", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR030737", 
            "id": "IPR030737", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", 
            "id": "IPR000048", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", 
            "id": "IPR011993", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", 
            "id": "IPR000904", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", 
            "id": "IPR023394", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", 
            "id": "IPR035999", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF16453", 
            "id": "PF16453", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01369", 
            "id": "PF01369", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF327", 
            "id": "PTHR10663:SF327", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1596313", 
            "id": "1596313", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2JUG7", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 108080.0, 
        "chemical_mass": 108080.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JUG7", 
            "name": "Iqsec1.", 
            "locus": {
                "end_pos": 123453478, 
                "start_pos": 123307624, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000060350", 
                        "id": "ENSRNOG00000060350", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}