{
    "uniprot_canonical_ac": "A0A0G2JTY1-1", 
    "sequence": {
        "header": "tr|A0A0G2JTY1-1|A0A0G2JTY1_RAT Isoform 1 of Grainyhead-like transcription factor 1  OS=Rattus norvegicus OX=10116 GN=Grhl1 PE=4 SV=1 CANONICAL=A0A0G2JTY1-1", 
        "length": 525, 
        "sequence": "NSIPNVTEQPLISAGENRVQVLKNVPFNIVLPHSNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTEIQPHGFTVGIPPAVYHSEPTERVVVFDRSLSTDQFSSGPQPPNAQRRTPDSTFSETFKEGVQEVFFPSELSLRMPGMTSEDYVFDSVSGNNFEYTLEASKSLRQKQGDSTMTYLNKGQFYPVTLKEVSSNEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIGEWPRSPPTSRRLQCPASQVLLLLAIINFLLKVFISVNCLSTDFSSQKGVKGLPLNIQIDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVSDVKVQLLPSHKRTDITVFKPFLDLDTQPVLFIPDVHFTNLQRGSHVLSLPTEELEGDGSVLKRGPFGTEDDFGVPPPAKLARTEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI"
    }, 
    "uniprot_id": "A0A0G2JTY1_RAT", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Grainyhead-like transcription factor 1"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "Grhl1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                    "id": "A0A0G2JTY1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "recommendedname": {
        "full": "Grainyhead-like transcription factor 1."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1#A0A0G2JTY1-1", 
            "isoform_ac": "A0A0G2JTY1-1", 
            "locus": {
                "end_pos": 43743702, 
                "start_pos": 43794342, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000082570", 
                        "id": "ENSRNOT00000082570", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068887", 
                        "id": "ENSRNOP00000068887", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2JTY1-1|A0A0G2JTY1_RAT Isoform 1 of Grainyhead-like transcription factor 1  OS=Rattus norvegicus OX=10116 GN=Grhl1 PE=4 SV=1 CANONICAL=A0A0G2JTY1-1", 
                "length": 525, 
                "sequence": "NSIPNVTEQPLISAGENRVQVLKNVPFNIVLPHSNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTEIQPHGFTVGIPPAVYHSEPTERVVVFDRSLSTDQFSSGPQPPNAQRRTPDSTFSETFKEGVQEVFFPSELSLRMPGMTSEDYVFDSVSGNNFEYTLEASKSLRQKQGDSTMTYLNKGQFYPVTLKEVSSNEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIGEWPRSPPTSRRLQCPASQVLLLLAIINFLLKVFISVNCLSTDFSSQKGVKGLPLNIQIDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVSDVKVQLLPSHKRTDITVFKPFLDLDTQPVLFIPDVHFTNLQRGSHVLSLPTEELEGDGSVLKRGPFGTEDDFGVPPPAKLARTEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9NZI5-1", 
            "protein_name": "Grainyhead-like protein 1 homolog; Mammalian grainyhead; Transcription factor CP2-like 2; NH32; Transcription factor LBP-32.", 
            "sequence": {
                "length": 618, 
                "sequence": "MTQEYDNKRPVLVLQNEALYPQRRSYTSEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRERRSSTAKPEVEHPEPDHSKRNSIPIVTEQPLISAGENRVQVLKNVPFNIVLPHGNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTETQPHGFAVGIPPAVYHPEPTERVVVFDRNLNTDQFSSGAQAPNAQRRTPDSTFSETFKEGVQEVFFPSDLSLRMPGMNSEDYVFDSVSGNNFEYTLEASKSLRQKPGDSTMTYLNKGQFYPITLKEVSSSEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEIAYNAISFTWDINDEAKVFISVNCLSTDFSSQKGVKGLPLNIQVDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVSDVKVPLLPSHKRMDITVFKPFIDLDTQPVLFIPDVHFANLQRGTHVLPIASEELEGEGSVLKRGPYGTEDDFAVPPSTKLARIEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2JTY1/", 
                    "id": "A0A0G2JTY1", 
                    "database": "OMA"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription factor activity", 
                        "id": "GO:0003700"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "sequence-specific DNA binding", 
                        "id": "GO:0043565"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "protein homodimerization activity", 
                        "id": "GO:0042803"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA polymerase II proximal promoter sequence-specific DNA binding", 
                        "id": "GO:0000978"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "chromatin DNA binding", 
                        "id": "GO:0031490"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", 
                        "id": "GO:0001228"
                    }
                ], 
                "total": 6, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoplasm", 
                        "id": "GO:0005654"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Golgi apparatus", 
                        "id": "GO:0005794"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
                                "id": "A0A0G2JTY1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of transcription by RNA polymerase II", 
                        "id": "GO:0006357"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 7, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 5
        }, 
        {
            "end_pos": 313, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 311
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000054989", 
            "id": "ENSRNOG00000054989", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/NLKRGPY/", 
            "id": "NLKRGPY", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007604", 
            "id": "IPR007604", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040167", 
            "id": "IPR040167", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF04516", 
            "id": "PF04516", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037", 
            "id": "PTHR11037", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305735", 
            "id": "1305735", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0G2JTY1", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 59394.0, 
        "chemical_mass": 59394.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2JTY1", 
            "name": "Grhl1.", 
            "locus": {
                "end_pos": 43794342, 
                "start_pos": 43743702, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000054989", 
                        "id": "ENSRNOG00000054989", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}