{
    "uniprot_canonical_ac": "A0A0A0MS06-1", 
    "sequence": {
        "header": "tr|A0A0A0MS06-1|A0A0A0MS06_HUMAN Isoform 1 of T cell receptor beta variable 23-1 (non-functional)  OS=Homo sapiens OX=9606 GN=TRBV23-1 PE=4 SV=6 CANONICAL=A0A0A0MS06-1", 
        "length": 115, 
        "sequence": "MGTRLLGCAALCLLAADSFHAKVTQTPGHLVKGKGQKTKMDCTPEKGHTFVYWYQQNQNKEFMLLISFQNEQVLQETEMHKKRFSSQCPKNAPCSLAILSSEPGDTALYLCASSQ"
    }, 
    "uniprot_id": "A0A0A0MS06_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "T cell receptor beta variable 23-1 (non-functional)"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "TRBV23-1"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0A0MS06", 
                    "id": "A0A0A0MS06", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "T cell receptor beta variable 23-1 (non-functional)."
    }, 
    "publication": [], 
    "glycosylation": [], 
    "mutation": [
        {
            "start_pos": 92, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A0A0MS06", 
                    "id": "A0A0A0MS06", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "1.4", 
            "annotation": "Filters passed (1/5): patient freq. (1.4%).", 
            "sequence_org": "A", 
            "disease": {
                "doid": "1612", 
                "url": "http://disease-ontology.org/term/DOID:1612", 
                "icd10": "", 
                "name": "Breast cancer"
            }, 
            "sequence_mut": "T", 
            "subjects_tested": "72", 
            "end_pos": 92, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0A0MS06#A0A0A0MS06-1", 
            "isoform_ac": "A0A0A0MS06-1", 
            "locus": {
                "end_pos": 142645961, 
                "start_pos": 142646465, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000390396", 
                        "id": "ENST00000390396", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000374919", 
                        "id": "ENSP00000374919", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0A0MS06-1|A0A0A0MS06_HUMAN Isoform 1 of T cell receptor beta variable 23-1 (non-functional)  OS=Homo sapiens OX=9606 GN=TRBV23-1 PE=4 SV=6 CANONICAL=A0A0A0MS06-1", 
                "length": 115, 
                "sequence": "MGTRLLGCAALCLLAADSFHAKVTQTPGHLVKGKGQKTKMDCTPEKGHTFVYWYQQNQNKEFMLLISFQNEQVLQETEMHKKRFSSQCPKNAPCSLAILSSEPGDTALYLCASSQ"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0A0MS06", 
                                "id": "A0A0A0MS06", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "immunological synapse", 
                        "id": "GO:0001772"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12201", 
            "id": "12201", 
            "database": "HGNC"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRBV23-1", 
            "id": "TRBV23-1", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211749", 
            "id": "ENSG00000211749", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/PRNSSCT/", 
            "id": "PRNSSCT", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", 
            "id": "IPR007110", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", 
            "id": "IPR013783", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", 
            "id": "IPR036179", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", 
            "id": "IPR013106", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07686", 
            "id": "PF07686", 
            "database": "Pfam"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0A0MS06", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 12785.0, 
        "chemical_mass": 12785.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0A0MS06", 
            "name": "TRBV23-1.", 
            "locus": {
                "end_pos": 142646467, 
                "start_pos": 142645961, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000211749", 
                        "id": "ENSG00000211749", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}