{ "uniprot_canonical_ac": "A0A096MJU6-1", "sequence": { "header": "tr|A0A096MJU6-1|A0A096MJU6_RAT Isoform 1 of PR domain containing 1, with ZNF domain (Predicted) OS=Rattus norvegicus OX=10116 GN=Prdm1 PE=4 SV=1 CANONICAL=A0A096MJU6-1", "length": 857, "sequence": "MSEAYLRCWIFSWKSVWVRPCQGLHFKTRLLQGSLLYTALDSYSTVQAAPKCNSGSVKFQGLAETSGIMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSSADGGTSVQAEASLPRNLLFKYAANNSKEVIGVVSKEYIPKGTRFGPLIGEVYTNDTVPKNANRKYFWRIYSREEFHHFIDGFNEEKSNWMRYVNPAHSAREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTVMNLTQTESNPKQYSSEKNELYPKSVPKREYSVKEILKLDSNPSKRKDSYRSNISPYTSEKDMDGFRKNGSPDMPFYPRVVYPIRAPLPEDFLKASLAYGMERPTYITHSPLPSSTTPSPPASSSPEQSLKSASPHGSPGNTVSPVVPGPPEHRDSYSYLNVSYGSEGLGSYPGYAPAPHLPPAFIPSYNAHYPKFLLPPYGISSNGLSTMNNINGINNFSLFPRLYPVYSNLLSGGNLPHPMLNPASLPSSLPTDGARRLLPPEHPREVLVPAPHSAFSLTGAAASMKDESSPPSGSPTAGTAATSEHVVQPKATSSVMAAPSTDGAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRDRPHKCAQCHKSYIHLCSLKVHLKGNCPVVPAPGLPLEDLTRINEEIERFDLSDNADRLEDMEDSVDVTSMVEKEILAIVRKEKEETGLKMSLQKTMGSRLPSSGCSLYESSDLSLMKLPHSNSLPLVPVKVKQETVEPMDP" }, "uniprot_id": "A0A096MJU6_RAT", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "PR domain zinc finger protein 1 isoform X2" ], "uniprotkb": [ "PR domain containing 1, with ZNF domain (Predicted)", "PR/SET domain 1" ] }, "gene": { "refseq": [ "Prdm1" ], "uniprotkb": [ "Prdm1", "Prdm1_predicted", "rCG_58519" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "recommendedname": { "full": "PR domain containing 1, with ZNF domain (Predicted); PR/SET domain 1." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6#A0A096MJU6-1", "isoform_ac": "A0A096MJU6-1", "locus": { "end_pos": 49467388, "start_pos": 49486345, "chromosome": "20", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000076541", "id": "ENSRNOT00000076541", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000068267", "id": "ENSRNOP00000068267", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A096MJU6-1|A0A096MJU6_RAT Isoform 1 of PR domain containing 1, with ZNF domain (Predicted) OS=Rattus norvegicus OX=10116 GN=Prdm1 PE=4 SV=1 CANONICAL=A0A096MJU6-1", "length": 857, "sequence": "MSEAYLRCWIFSWKSVWVRPCQGLHFKTRLLQGSLLYTALDSYSTVQAAPKCNSGSVKFQGLAETSGIMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSSADGGTSVQAEASLPRNLLFKYAANNSKEVIGVVSKEYIPKGTRFGPLIGEVYTNDTVPKNANRKYFWRIYSREEFHHFIDGFNEEKSNWMRYVNPAHSAREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTVMNLTQTESNPKQYSSEKNELYPKSVPKREYSVKEILKLDSNPSKRKDSYRSNISPYTSEKDMDGFRKNGSPDMPFYPRVVYPIRAPLPEDFLKASLAYGMERPTYITHSPLPSSTTPSPPASSSPEQSLKSASPHGSPGNTVSPVVPGPPEHRDSYSYLNVSYGSEGLGSYPGYAPAPHLPPAFIPSYNAHYPKFLLPPYGISSNGLSTMNNINGINNFSLFPRLYPVYSNLLSGGNLPHPMLNPASLPSSLPTDGARRLLPPEHPREVLVPAPHSAFSLTGAAASMKDESSPPSGSPTAGTAATSEHVVQPKATSSVMAAPSTDGAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRDRPHKCAQCHKSYIHLCSLKVHLKGNCPVVPAPGLPLEDLTRINEEIERFDLSDNADRLEDMEDSVDVTSMVEKEILAIVRKEKEETGLKMSLQKTMGSRLPSSGCSLYESSDLSLMKLPHSNSLPLVPVKVKQETVEPMDP" } }, { "url": "https://www.uniprot.org/uniprot/A0A096MJU6#D4A1S2-1", "isoform_ac": "D4A1S2-1", "locus": { "end_pos": 49467388, "start_pos": 49486325, "chromosome": "20", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000048270", "id": "ENSRNOT00000048270", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000040939", "id": "ENSRNOP00000040939", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D4A1S2-1|A0A096MJU6_RAT Computationally mapped isoform of PR domain containing 1, with ZNF domain (Predicted) OS=Rattus norvegicus OX=10116 GN=Prdm1 PE=4 SV=1 CANONICAL=A0A096MJU6-1", "length": 824, "sequence": "MLDLLLEKRVGTTLAAPKCNSGSVKFQGLAETSGIMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSSADGGTSVQAEASLPRNLLFKYAANNSKEVIGVVSKEYIPKGTRFGPLIGEVYTNDTVPKNANRKYFWRIYSREEFHHFIDGFNEEKSNWMRYVNPAHSAREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTVMNLTQTESNPKQYSSEKNELYPKSVPKREYSVKEILKLDSNPSKRKDSYRSNISPYTSEKDMDGFRKNGSPDMPFYPRVVYPIRAPLPEDFLKASLAYGMERPTYITHSPLPSSTTPSPPASSSPEQSLKSASPHGSPGNTVSPVVPGPPEHRDSYSYLNVSYGSEGLGSYPGYAPAPHLPPAFIPSYNAHYPKFLLPPYGISSNGLSTMNNINGINNFSLFPRLYPVYSNLLSGGNLPHPMLNPASLPSSLPTDGARRLLPPEHPREVLVPAPHSAFSLTGAAASMKDESSPPSGSPTAGTAATSEHVVQPKATSSVMAAPSTDGAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRDRPHKCAQCHKSYIHLCSLKVHLKGNCPVVPAPGLPLEDLTRINEEIERFDLSDNADRLEDMEDSVDVTSMVEKEILAIVRKEKEETGLKMSLQKTMGSRLPSSGCSLYESSDLSLMKLPHSNSLPLVPVKVKQETVEPMDP" } } ], "pathway": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "O75626-1", "protein_name": "PR domain zinc finger protein 1; 2.1.1.-; Positive regulatory domain I-binding factor 1; PRDI-BF1; PRDI-binding factor 1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; BLIMP-1.", "sequence": { "length": 825, "sequence": "MLDICLEKRVGTTLAAPKCNSSTVRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEILKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKASLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEHRDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAVSSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPREVLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSDEAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGLPLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSLQRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A0A096MJU6/", "id": "A0A096MJU6", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/925", "id": "925", "database": "MGI" } ], "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q60636-1", "protein_name": "PR domain zinc finger protein 1; 2.1.1.-; B lymphocyte-induced maturation protein 1; Blimp-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1.", "sequence": { "length": 856, "sequence": "MREAYLRCWIFSWKNVWVRPCQRLHFKTVLLQGSLLYTALDSYSTVQAAPKSSSGSVKFQGLAETGIMKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRNLLFKYAANNSKEVIGVVSKEYIPKGTRFGPLIGEVYTNDTVPKNANRKYFWRIYSREEFHHFIDGFNEEKSNWMRYVNPAHSAREQNLAACQNGMNIYFYTIKPIPANQELLVWYCRDFAERLHYPYPGELTVINLTQTESNPKQYSSEKNELYPKSVPKREYSVKEILKLDSNPSKRKDIYRSNISPFTLEKDMDGFRKNGSPDMPFYPRVVYPIRAPLPEDFLKASLAYGMERPTYITHSPLPSSTTPSPPASSSPEQSLKSSSPHSSPGNTVSPLAPGLPEHRDSYSYLNVSYGSEGLGSYPGYAPAPHLPPAFIPSYNAHYPKFLLPPYGISSNGLSTMNNINGINNFSLFPRLYPVYSNLLSGSSLPHPMLNPASLPSSLPTDGARRLLPPEHPKEVLIPAPHSAFSLTGAAASMKDESSPPSGSPTAGTAATSEHVVQPKATSSVMAAPSTDGAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERPFKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQCKVCPAKFTQFVHLKLHKRLHTRERPHKCAQCHKSYIHLCSLKVHLKGNCPAGPAAGLPLEDLTRINEEIERFDISDNADRLEDMEDSVDVTSMVEKEILAVVRKEKEETSLKVSLQRNMGNGLLSSGCSLYESSDLSLMKLPHSNPLPLVPVKVKQETVEPMDP" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/925", "id": "925", "database": "MGI" } ], "organism": "Mus musculus", "tax_id": 10090 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771213.1", "ac": "XP_008771213.1", "name": "PR domain zinc finger protein 1 isoform X2.", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "DNA-binding transcription factor activity", "id": "GO:0003700" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "histone deacetylase binding", "id": "GO:0042826" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "RNA polymerase II regulatory region sequence-specific DNA binding", "id": "GO:0000977" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "chromatin DNA binding", "id": "GO:0031490" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "sequence-specific DNA binding", "id": "GO:0043565" } ], "total": 5, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "id": "A0A096MJU6", "database": "UniProtKB" } ], "name": "cell fate commitment", "id": "GO:0045165" } ], "total": 1, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 128, "annotation": "n_glycosylation_sequon", "start_pos": 126 }, { "end_pos": 158, "annotation": "n_glycosylation_sequon", "start_pos": 156 }, { "end_pos": 255, "annotation": "n_glycosylation_sequon", "start_pos": 253 }, { "end_pos": 305, "annotation": "n_glycosylation_sequon", "start_pos": 303 }, { "end_pos": 321, "annotation": "n_glycosylation_sequon", "start_pos": 319 }, { "end_pos": 413, "annotation": "n_glycosylation_sequon", "start_pos": 411 }, { "end_pos": 471, "annotation": "n_glycosylation_sequon", "start_pos": 469 }, { "end_pos": 589, "annotation": "n_glycosylation_sequon", "start_pos": 587 } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_008771213.1", "id": "XP_008771213.1", "database": "RefSeq" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000000323", "id": "ENSRNOG00000000323", "database": "Bgee" }, { "url": "https://omabrowser.org/oma/group/NFNLFPR/", "id": "NFNLFPR", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "id": "IPR013087", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "id": "IPR036236", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "id": "IPR001214", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00856", "id": "PF00856", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00096", "id": "PF00096", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/309871", "id": "309871", "database": "GeneID" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311765", "id": "1311765", "database": "RGD" } ], "expression_disease": [], "uniprot_ac": "A0A096MJU6", "disease": [], "mass": { "monoisotopic_mass": 95906.0, "chemical_mass": 95906.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A096MJU6", "name": "Prdm1; Prdm1_predicted; rCG_58519.", "locus": { "end_pos": 49464919, "start_pos": 49556518, "chromosome": "20", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000000323", "id": "ENSRNOG00000000323", "database": "Ensembl Gene" } ] } } ] }