{
    "uniprot_canonical_ac": "A0A075B712-1", 
    "sequence": {
        "header": "tr|A0A075B712-1|A0A075B712_HUMAN Isoform 1 of T cell receptor alpha joining 54  OS=Homo sapiens OX=9606 GN=TRAJ54 PE=4 SV=1 CANONICAL=A0A075B712-1", 
        "length": 20, 
        "sequence": "XIQGAQKLVFGQGTRLTINP"
    }, 
    "uniprot_id": "A0A075B712_HUMAN", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "T cell receptor alpha joining 54"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "TRAJ54"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A075B712", 
                    "id": "A0A075B712", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {
        "full": "T cell receptor alpha joining 54."
    }, 
    "publication": [], 
    "glycosylation": [], 
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        {
            "start_pos": 3, 
            "subjects_positive": "31", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B712", 
                    "id": "A0A075B712", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (2/5): patient freq. (2.0%); patient count (31/1514).", 
            "sequence_org": "Q", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "H", 
            "subjects_tested": "1514", 
            "end_pos": 3, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 5, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B712", 
                    "id": "A0A075B712", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "A", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "D", 
            "subjects_tested": "50", 
            "end_pos": 5, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 6, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B712", 
                    "id": "A0A075B712", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "2.0", 
            "annotation": "Filters passed (1/5): patient freq. (2.0%).", 
            "sequence_org": "Q", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "R", 
            "subjects_tested": "50", 
            "end_pos": 6, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B712#A0A075B712-1", 
            "isoform_ac": "A0A075B712-1", 
            "locus": {
                "end_pos": 22482287, 
                "start_pos": 22482346, 
                "chromosome": "14", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000390484", 
                        "id": "ENST00000390484", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000452564", 
                        "id": "ENSP00000452564", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A075B712-1|A0A075B712_HUMAN Isoform 1 of T cell receptor alpha joining 54  OS=Homo sapiens OX=9606 GN=TRAJ54 PE=4 SV=1 CANONICAL=A0A075B712-1", 
                "length": 20, 
                "sequence": "XIQGAQKLVFGQGTRLTINP"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {}, 
    "site_annotation": [], 
    "crossref": [
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12086", 
            "id": "12086", 
            "database": "HGNC"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRAJ54", 
            "id": "TRAJ54", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211836", 
            "id": "ENSG00000211836", 
            "database": "Bgee"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A075B712", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 2153.0, 
        "chemical_mass": 2153.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B712", 
            "name": "TRAJ54.", 
            "locus": {
                "end_pos": 22482346, 
                "start_pos": 22482287, 
                "chromosome": "14", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000211836", 
                        "id": "ENSG00000211836", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}