{ "uniprot_canonical_ac": "A2AVC7-1", "sequence": { "header": "tr|A2AVC7-1|A2AVC7_MOUSE Isoform 1 of Olfactory receptor 1145 OS=Mus musculus OX=10090 GN=Olfr1145 PE=3 SV=1 CANONICAL=A2AVC7-1", "length": 325, "sequence": "MTQTPTKSFLQMKHDEIEAEVNISTVIQFVLLGFSALPNLQGILSALFSIIYRIILTGNCLIILITRLDHTLHKPMYFFLANFSSLEICYVSVTVPRILFNIWTQDRNISVLACAVQMCFFLMLGTDECFLLAVMSYDRYVAICNPLHYPLIMNSKKCTQLAAGSWLSGIPIQIGQTCWIFSMHFCDSNEIDHFFCDIPPILKLACGDTSVHELSVYVVVMVVAAFPFILVLTSYSKIIATILRLPTAKGRAKAFSTCSSHLLVVVLFYGSGTITYLRPKSTHSPGIDKLLSLFYTIVTPMFNPLIYSLRNKEVVVALRKLILQK" }, "uniprot_id": "A2AVC7_MOUSE", "enzyme_annotation": [], "synonyms": { "protein": { "refseq": [ "olfactory receptor 1145", "olfactory receptor MOR264-19; GA_x6K02T2Q125-49311440-49312384" ], "uniprotkb": [ "Olfactory receptor 1145", "Olfr1145" ] }, "gene": { "refseq": [ "Olfr1145", "MOR264-19" ], "uniprotkb": [ "Olfr1145", "MOR264-19" ] } }, "keywords": [], "species": [ { "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "recommendedname": { "full": "Olfactory receptor 1145; Olfr1145." }, "publication": [], "glycosylation": [], "mutation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7#A2AV42-1", "isoform_ac": "A2AV42-1", "locus": { "end_pos": 87809855, "start_pos": 87810796, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000079711", "id": "ENSMUST00000079711", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000078649", "id": "ENSMUSP00000078649", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AV42-1|A2AVC7_MOUSE Computationally mapped isoform of Olfactory receptor 1145 OS=Mus musculus OX=10090 GN=Olfr1145 PE=3 SV=2 CANONICAL=A2AVC7-1", "length": 314, "sequence": "MKHDEIEAEVNISTVIQFVLLGFSALPNLQGILSALFSIIYRIILTGNCLIILITRLDHTLHKPMYFFLANFSSLEICYVSVTVPRILFNIWTQDRNISVLACAVQMCFFLMLGTDECFLLAVMSYDRYVAICNPLHYPLIMNSKKCTQLAAGSWLSGIPIQIGQTCWIFSMHFCDSNEIDHFFCDIPPILKLACGDTSVHELSVYVVVMVVAAFPFILVLTSYSKIIATILRLPTAKGRAKAFSTCSSHLLVVVLFYGSGTITYLRPKSTHSPGIDKLLSLFYTIVTPMFNPLIYSLRNKEVVVALRKLILQK" } }, { "url": "https://www.uniprot.org/uniprot/A2AVC7#A2AVC7-1", "isoform_ac": "A2AVC7-1", "locus": { "end_pos": 87809822, "start_pos": 87810796, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000090707", "id": "ENSMUST00000090707", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000088209", "id": "ENSMUSP00000088209", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AVC7-1|A2AVC7_MOUSE Isoform 1 of Olfactory receptor 1145 OS=Mus musculus OX=10090 GN=Olfr1145 PE=3 SV=1 CANONICAL=A2AVC7-1", "length": 325, "sequence": "MTQTPTKSFLQMKHDEIEAEVNISTVIQFVLLGFSALPNLQGILSALFSIIYRIILTGNCLIILITRLDHTLHKPMYFFLANFSSLEICYVSVTVPRILFNIWTQDRNISVLACAVQMCFFLMLGTDECFLLAVMSYDRYVAICNPLHYPLIMNSKKCTQLAAGSWLSGIPIQIGQTCWIFSMHFCDSNEIDHFFCDIPPILKLACGDTSVHELSVYVVVMVVAAFPFILVLTSYSKIIATILRLPTAKGRAKAFSTCSSHLLVVVLFYGSGTITYLRPKSTHSPGIDKLLSLFYTIVTPMFNPLIYSLRNKEVVVALRKLILQK" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:258317", "resource": "KEGG Pathway", "id": "mmu:258317", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "M0RD58-1", "protein_name": "Olfactory receptor 592.", "sequence": { "length": 311, "sequence": "MKHEVEAEGNISTVMQFVLLGFSALPNLQGILSALFSLIYMIILTGNCLIILITRLDHTLQKPMYFFLANFSCLEICYVSVTVPRILFNIWTQDRNISVLACAVQMCFFLMLGTDECFLLAVMSYDRYVAICNPLHYPVVMNSKKCTQLAAGSWISGIPIQIGQTCWIFSMHFCNSNEIDHFFCDIPPILKLACGDTSVHELSVYVVVMVVAAFPFILVLTSYSKIIATILRLPTAKGRAKAFSTCSSHLLVVVLFYGSGTITYLRPKSMHNPGTDKLLSLFYTIVTPMFNPLIYTLRNKEVIVALRKLIV" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/27123", "id": "27123", "database": "MGI" } ], "organism": "Rattus norvegicus", "tax_id": 10116 } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666432.2", "ac": "NP_666432.2", "name": "olfactory receptor 1145; olfactory receptor MOR264-19; GA_x6K02T2Q125-49311440-49312384.", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]." }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "olfactory receptor activity", "id": "GO:0004984" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "G protein-coupled receptor activity", "id": "GO:0004930" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "plasma membrane", "id": "GO:0005886" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "id": "A2AVC7", "database": "UniProtKB" } ], "name": "sensory perception of smell", "id": "GO:0007608" } ], "total": 2, "name": "Biological Process" } ] }, "site_annotation": [ { "end_pos": 24, "annotation": "n_glycosylation_sequon", "start_pos": 22 }, { "end_pos": 84, "annotation": "n_glycosylation_sequon", "start_pos": 82 }, { "end_pos": 110, "annotation": "n_glycosylation_sequon", "start_pos": 108 } ], "crossref": [ { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "id": "IPR000276", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "id": "IPR017452", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "id": "IPR000725", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF13853", "id": "PF13853", "database": "Pfam" }, { "url": "http://www.informatics.jax.org/marker/MGI:3030979", "id": "3030979", "database": "MGI" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_666432.2", "id": "NP_666432.2", "database": "RefSeq" }, { "url": "https://www.genome.jp/dbget-bin/www_bget?mmu:258317", "id": "mmu:258317", "database": "KEGG Pathway" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/258317", "id": "258317", "database": "GeneID" } ], "expression_disease": [], "uniprot_ac": "A2AVC7", "disease": [], "mass": { "monoisotopic_mass": 36561.0, "chemical_mass": 36561.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AVC7", "name": "Olfr1145; MOR264-19.", "locus": { "end_pos": 87810799, "start_pos": 87809822, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000068814", "id": "ENSMUSG00000068814", "database": "Ensembl Gene" } ] } } ] }