{
    "uniprot_canonical_ac": "A2AF53-1", 
    "sequence": {
        "header": "sp|A2AF53-1|T185A_MOUSE Isoform 1 of Transmembrane protein 185A  OS=Mus musculus OX=10090 GN=Tmem185a PE=1 SV=1 CANONICAL=A2AF53-1", 
        "length": 350, 
        "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD"
    }, 
    "uniprot_id": "T185A_MOUSE", 
    "enzyme_annotation": [], 
    "synonyms": {
        "protein": {
            "refseq": [], 
            "uniprotkb": [
                "Transmembrane protein 185A", 
                "Protein FAM11A", 
                "Erythropoietin-induced EST 3"
            ]
        }, 
        "gene": {
            "refseq": [], 
            "uniprotkb": [
                "Tmem185a", 
                "Ee3", 
                "Tmem185a", 
                "Fam11a"
            ]
        }
    }, 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AF53", 
                    "id": "A2AF53", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "recommendedname": {
        "full": "Transmembrane protein 185A; Protein FAM11A; Erythropoietin-induced EST 3."
    }, 
    "publication": [
        {
            "title": "Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor.", 
            "url": "https://www.ncbi.nlm.nih.gov/pubmed/15525354", 
            "journal": "J. Neurochem.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AF53/publications", 
                    "id": "A2AF53", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Schneider A., Gassler N., Gruenewald S., Kuner T., Rossner M., Weber D., Kuschinsky W., Maurer M.H., Propst F., Wuerz R.", 
            "date": "2004", 
            "pmid": "15525354"
        }
    ], 
    "glycosylation": [], 
    "mutation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AF53#A2AF53-1", 
            "isoform_ac": "A2AF53-1", 
            "locus": {
                "end_pos": 70461051, 
                "start_pos": 70477015, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000114630", 
                        "id": "ENSMUST00000114630", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110277", 
                        "id": "ENSMUSP00000110277", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AF53-1|T185A_MOUSE Isoform 1 of Transmembrane protein 185A  OS=Mus musculus OX=10090 GN=Tmem185a PE=1 SV=1 CANONICAL=A2AF53-1", 
                "length": 350, 
                "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AF53#Q3TYW3-1", 
            "isoform_ac": "Q3TYW3-1", 
            "locus": {
                "end_pos": 70461051, 
                "start_pos": 70477015, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000101506", 
                        "id": "ENSMUST00000101506", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000099043", 
                        "id": "ENSMUSP00000099043", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|Q3TYW3-1|T185A_MOUSE Computationally mapped isoform of Transmembrane protein 185A  OS=Mus musculus OX=10090 GN=Tmem185a PE=1 SV=1 CANONICAL=A2AF53-1", 
                "length": 322, 
                "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLEVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8NFB2-1", 
            "protein_name": "Transmembrane protein 185A; Protein FAM11A.", 
            "sequence": {
                "length": 350, 
                "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSSIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDNEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/66313", 
                    "id": "66313", 
                    "database": "MGI"
                }
            ], 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "D3ZWX2-1", 
            "protein_name": "Transmembrane protein 185A.", 
            "sequence": {
                "length": 350, 
                "sequence": "MNLRGLFQDFNPSKFLIYACLLLFSVLLALRLDGIIQWSYWAVFAPIWLWKLMVIVGASVGTGVWARNPQYRAEGETCVEFKAMLIAVGIHLLLLMFEVLVCDRIERGSHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDKIIHWPWLVVCVPLWILMSFLCLVVLYYIVWSVLFLRSMDVIAEQRRTHITMALSWMTIVVPLLTFEILLVHKLDGHNAFSCIPIFVPLWLSLITLMATTFGQKGGNHWWFGIRKDFCQFLLEIFPFLREYGNISYDLHHEDSEETEETPVPEPPKIAPMFRKKARVVITQSPGKYVLPPPKLNIEMPD"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/66313", 
                    "id": "66313", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A2AF53/", 
                    "id": "A2AF53", 
                    "database": "OMA"
                }
            ], 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AF53", 
                                "id": "A2AF53", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "dendrite", 
                        "id": "GO:0030425"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AF53", 
                                "id": "A2AF53", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 296, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 294
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019396", 
            "id": "IPR019396", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF10269", 
            "id": "PF10269", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2448555", 
            "id": "2448555", 
            "database": "MGI"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006528044.1", 
            "id": "XP_006528044.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000073139", 
            "id": "ENSMUSG00000073139", 
            "database": "Bgee"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/VWAHNPQ/", 
            "id": "VWAHNPQ", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568", 
            "id": "PTHR13568", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AF53", 
            "id": "PR_A2AF53", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/236848", 
            "id": "236848", 
            "database": "GeneID"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A2AF53", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 40620.0, 
        "chemical_mass": 40620.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AF53", 
            "name": "Tmem185a; Ee3; Tmem185a; Fam11a.", 
            "locus": {
                "end_pos": 70459753, 
                "start_pos": 70477180, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000073139", 
                        "id": "ENSMUSG00000073139", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}