4,5d3
< "A0A0G2K0R0-1","2.1.1.-",""
< "A0A0G2K0R0-1","2.1.1.-",""
27,28d24
< "O08617-1","3.1.3.48","Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate."
< "O08617-1","3.1.3.48",""
63,64d58
< "Q32Q05-1","3.4.19.12","Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)."
< "Q32Q05-1","3.4.19.12",""
71,72c65,66
< "Q99P55-1","3.1.3.-",""
< "Q99P55-1","3.1.3.-",""
---
> "F1LS72-1","2.3.2.-",""
> "F1LS72-1","2.3.2.-",""
396,397c390,393
< "P50298-1","2.3.1.5","Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine."
< "P50298-1","2.3.1.5",""
---
> "P50393-1","3.1.1.4","Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate."
> "P50393-1","3.1.1.5","2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate."
> "Q9JJH5-1","2.7.1.105","ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate."
> "Q9JJH5-1","3.1.3.46","Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate."
456a453,454
> "P22985-1","1.17.1.4","Xanthine + NAD(+) + H(2)O = urate + NADH."
> "P22985-1","1.17.3.2","Xanthine + H(2)O + O(2) = urate + H(2)O(2)."
483,485d480
< "Q64611-1","4.1.1.29","3-sulfino-L-alanine = hypotaurine + CO(2)."
< "Q64611-1","4.1.1.11","L-aspartate = beta-alanine + CO(2)."
< "Q64611-1","4.1.1.29",""
533a529,530
> "O88202-1","3.5.1.1","L-asparagine + H(2)O = L-aspartate + NH(3)."
> "O88202-1","3.1.1.47","1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl-sn-glycero-3-phosphocholine + acetate."
550,551d546
< "Q5RKJ1-1","2.3.2.27","S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine."
< "Q5RKJ1-1","2.3.2.27",""
564a560,561
> "Q62878-1","1.1.1.145","A 3-beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + NADH."
> "Q62878-1","5.3.3.1","A 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid."
635a633,635
> "P07896-1","1.1.1.35","(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH."
> "P07896-1","4.2.1.17","(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O."
> "P07896-1","5.3.3.8","A (3E)-alk-3-enoyl-CoA = a (2E)-alk-2-enoyl-CoA."
644,645d643
< "O88994-1","1.-.-.-",""
< "O88994-1","1.-.-.-",""
683,684c681,683
< "Q99P84-1","3.1.4.11","1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol."
< "Q99P84-1","3.1.4.11",""
---
> "P97852-1","1.1.1.n12","(R)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH."
> "P97852-1","4.2.1.107","(24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestanoyl-CoA = (24E)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA + H(2)O."
> "P97852-1","4.2.1.119","(3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H(2)O."
750,753c749,751
< "P61131-1","2.4.99.2","CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R = CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R."
< "P61131-1","2.4.99.4","CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R."
< "P61131-1","2.4.99.4",""
< "P61131-1","2.4.99.2",""
---
> "P18266-1","2.7.11.1","ATP + a protein = ADP + a phosphoprotein."
> "P18266-1","2.7.11.26","ATP + [tau protein] = ADP + [tau protein] phosphate."
> "P18266-1","2.7.11.26",""
757a756,757
> "Q6P7A1-1","2.4.2.-",""
> "Q6P7A1-1","2.4.1.-",""
812a813,816
> "O35552-1","2.7.1.105","ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate."
> "O35552-1","3.1.3.46","Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate."
> "P16453-1","4.1.1.22","L-histidine = histamine + CO(2)."
> "P16453-1","4.1.1.22",""
824a829,830
> "O35826-1","2.7.1.60","ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate."
> "O35826-1","3.2.1.183","UDP-N-acetyl-alpha-D-glucosamine + H(2)O = N-acetyl-D-mannosamine + UDP."
849a856,857
> "D3ZH30-1","2.7.7.50","GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA."
> "D3ZH30-1","3.1.3.33","A 5'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate."
856,857c864,865
< "Q6AXU4-1","2.3.2.27","S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine."
< "Q6AXU4-1","2.3.2.27",""
---
> "M0R660-1","1.2.1.12","D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH."
> "M0R660-1","1.2.1.12",""
861,862c869,870
< "P56558-1","2.4.1.255","UDP-N-acetyl-alpha-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine."
< "P56558-1","2.4.1.255",""
---
> "Q505J9-1","3.6.1.3","ATP + H(2)O = ADP + phosphate."
> "Q505J9-1","3.6.1.3",""
871,872d878
< "D4A229-1","2.7.11.13","ATP + a protein = ADP + a phosphoprotein."
< "D4A229-1","2.7.11.13",""
918a925,926
> "A0A0G2K0R0-1","2.1.1.-",""
> "A0A0G2K0R0-1","2.1.1.-",""
966a975,976
> "Q6AY19-1","2.7.-.-",""
> "Q6AY19-1","2.7.-.-",""
1163,1164d1172
< "B2RYR0-1","2.3.2.27","S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine."
< "B2RYR0-1","2.3.2.27",""
1204,1205d1211
< "M0R660-1","1.2.1.12","D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH."
< "M0R660-1","1.2.1.12",""
1230a1237,1238
> "O35567-1","2.1.2.3","10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide."
> "O35567-1","3.5.4.10","IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide."
1292,1293c1300,1303
< "D3ZHQ5-1","3.2.1.23","Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides."
< "D3ZHQ5-1","3.2.1.23",""
---
> "P80299-1","3.3.2.10","An epoxide + H(2)O = a glycol."
> "P80299-1","3.1.3.76","(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate."
> "P14925-1","1.14.17.3","[Peptide]-glycine + 2 ascorbate + O(2) = [peptide]-(2S)-2-hydroxyglycine + 2 monodehydroascorbate + H(2)O."
> "P14925-1","4.3.2.5","[Peptide]-(2S)-2-hydroxyglycine = [peptide]-amide + glyoxylate."
1337a1348,1349
> "Q5RKJ1-1","2.3.2.27","S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine."
> "Q5RKJ1-1","2.3.2.27",""
1354,1355d1365
< "Q6AY19-1","2.7.-.-",""
< "Q6AY19-1","2.7.-.-",""
1417,1420d1426
< "Q5M868-1","3.2.1.45","D-glucosyl-N-acylsphingosine + H(2)O = D-glucose + N-acylsphingosine."
< "Q5M868-1","2.4.1.-",""
< "Q5M868-1","3.2.1.104","Cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol."
< "Q5M868-1","3.2.1.45",""
1422a1429,1430
> "Q63450-1","2.7.11.17","ATP + a protein = ADP + a phosphoprotein."
> "Q63450-1","2.7.11.17",""
1477,1478d1484
< "D3ZVQ0-1","3.4.19.12","Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)."
< "D3ZVQ0-1","3.4.19.12",""
1513,1514d1518
< "P80201-1","2.7.11.30","ATP + [receptor-protein] = ADP + [receptor-protein] phosphate."
< "P80201-1","2.7.11.30",""
1526a1531,1533
> "Q4KLZ6-1","2.7.1.28","ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate."
> "Q4KLZ6-1","2.7.1.29","ATP + glycerone = ADP + glycerone phosphate."
> "Q4KLZ6-1","4.6.1.15","FAD = AMP + riboflavin cyclic-4',5'-phosphate."
1542,1543c1549,1550
< "Q64568-1","7.2.2.10","ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)."
< "Q64568-1","7.2.2.10",""
---
> "P97675-1","3.1.4.1","Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides."
> "P97675-1","3.6.1.9","A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate."
1558,1559c1565,1566
< "Q5CZZ9-1","2.7.1.68","ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."
< "Q5CZZ9-1","2.7.1.68",""
---
> "Q923S8-1","3.1.3.-",""
> "Q923S8-1","2.7.1.33","ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate."
1617,1618d1623
< "D3ZFC5-1","7.6.2.1","ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)."
< "D3ZFC5-1","7.6.2.1",""
1640a1646,1647
> "P51583-1","4.1.1.21","5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)."
> "P51583-1","6.3.2.6","ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate."
1756a1764,1765
> "D4A5A6-1","2.7.7.6","Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)."
> "D4A5A6-1","2.7.7.6",""
1771,1772d1779
< "O08874-1","2.7.11.13","ATP + a protein = ADP + a phosphoprotein."
< "O08874-1","2.7.11.13",""
1826a1834,1836
> "Q5U367-1","2.4.1.50","UDP-alpha-D-galactose + [procollagen]-(2S,5R)-5-hydroxy-L-lysine = UDP + [procollagen]-(2S,5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysine."
> "Q5U367-1","1.14.11.4","L-lysine-[procollagen] + 2-oxoglutarate + O(2) = (2S,5R)-5-hydroxy-L-lysine-[procollagen] + succinate + CO(2)."
> "Q5U367-1","2.4.1.66","UDP-alpha-D-glucose + [procollagen]-(2S,5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysine = UDP + [procollagen]-(2S,5R)-5-O-(alpha-D-glucosyl-(1->2)-beta-D-galactosyl)-5-hydroxy-L-lysine."
1940a1951,1952
> "Q63707-1","1.3.5.2","(S)-dihydroorotate + a quinone = orotate + a quinol."
> "Q63707-1","1.3.5.2",""
1984,1985c1996,1997
< "F1LS72-1","2.3.2.-",""
< "F1LS72-1","2.3.2.-",""
---
> "Q99P55-1","3.1.3.-",""
> "Q99P55-1","3.1.3.-",""
2070a2083,2084
> "D3ZIE9-1","1.2.1.41","L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH."
> "D3ZIE9-1","2.7.2.11","ATP + L-glutamate = ADP + L-glutamate 5-phosphate."
2096a2111,2112
> "Q920R3-1","1.14.19.44","(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = arachidonoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O."
> "Q920R3-1","1.14.19.44",""
2121a2138,2139
> "Q6AXU4-1","2.3.2.27","S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine."
> "Q6AXU4-1","2.3.2.27",""
2129a2148,2149
> "D3ZHQ5-1","3.2.1.23","Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides."
> "D3ZHQ5-1","3.2.1.23",""
2182,2184c2202,2203
< "P18266-1","2.7.11.1","ATP + a protein = ADP + a phosphoprotein."
< "P18266-1","2.7.11.26","ATP + [tau protein] = ADP + [tau protein] phosphate."
< "P18266-1","2.7.11.26",""
---
> "O54728-1","3.1.1.4","Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate."
> "O54728-1","3.1.1.5","2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate."
2278a2298,2299
> "O08874-1","2.7.11.13","ATP + a protein = ADP + a phosphoprotein."
> "O08874-1","2.7.11.13",""
2310a2332,2334
> "P27653-1","6.3.4.3","ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate."
> "P27653-1","1.5.1.5","5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH."
> "P27653-1","3.5.4.9","5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate."
2413,2414d2436
< "Q9JJS8-1","3.4.21.104","Selective cleavage after Arg-223 in complement component C2 (-Ser-Leu-Gly-Arg-|-Lys-Ile-Gln-Ile) and after Arg-76 in complement component C4 (-Gly-Leu-Gln-Arg-|-Ala-Leu-Glu-Ile)."
< "Q9JJS8-1","3.4.21.104",""
2514a2537,2538
> "D4A229-1","2.7.11.13","ATP + a protein = ADP + a phosphoprotein."
> "D4A229-1","2.7.11.13",""
2565,2566d2588
< "P48769-1","2.7.1.74","NTP + deoxycytidine = NDP + dCMP."
< "P48769-1","2.7.1.74",""
2681,2682c2703,2705
< "Q9JHW0-1","3.4.25.1","Cleavage of peptide bonds with very broad specificity."
< "Q9JHW0-1","3.4.25.1",""
---
> "P00786-1","3.4.22.16","Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase."
> "O88994-1","1.-.-.-",""
> "O88994-1","1.-.-.-",""
2770a2794,2795
> "P50298-1","2.3.1.5","Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine."
> "P50298-1","2.3.1.5",""
2777,2778c2802,2803
< "Q505J9-1","3.6.1.3","ATP + H(2)O = ADP + phosphate."
< "Q505J9-1","3.6.1.3",""
---
> "A2VCW9-1","1.5.1.8","N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NADP(+) + H(2)O = L-lysine + 2-oxoglutarate + NADPH."
> "A2VCW9-1","1.5.1.9","N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-glutamate + (S)-2-amino-6-oxohexanoate + NADH."
2796a2822,2823
> "P07953-1","2.7.1.105","ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate."
> "P07953-1","3.1.3.46","Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate."
2876a2904,2907
> "Q5M868-1","3.2.1.45","D-glucosyl-N-acylsphingosine + H(2)O = D-glucose + N-acylsphingosine."
> "Q5M868-1","2.4.1.-",""
> "Q5M868-1","3.2.1.104","Cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol."
> "Q5M868-1","3.2.1.45",""
2937,2938c2968,2969
< "Q63484-1","2.7.11.1","ATP + a protein = ADP + a phosphoprotein."
< "Q63484-1","2.7.11.1",""
---
> "P48769-1","2.7.1.74","NTP + deoxycytidine = NDP + dCMP."
> "P48769-1","2.7.1.74",""
2973a3005
> "Q64428-1","4.2.1.17","(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O."
2974a3007
> "Q64428-1","1.1.1.211","A long-chain (S)-3-hydroxyacyl-CoA + NAD(+) = a long-chain 3-oxoacyl-CoA + NADH."
3116a3150,3151
> "Q02401-1","3.2.1.108","Lactose + H(2)O = D-galactose + D-glucose."
> "Q02401-1","3.2.1.62","Glycosyl-N-acylsphingosine + H(2)O = N-acylsphingosine + a sugar."
3124a3160,3161
> "B2RYR0-1","2.3.2.27","S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine."
> "B2RYR0-1","2.3.2.27",""
3193a3231,3232
> "D3ZVQ0-1","3.4.19.12","Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)."
> "D3ZVQ0-1","3.4.19.12",""
3240a3280,3281
> "P22072-1","1.1.1.145","A 3-beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + NADH."
> "P22072-1","5.3.3.1","A 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid."
3262a3304,3305
> "O88618-1","2.1.2.5","5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate."
> "O88618-1","4.3.1.4","5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3)."
3306a3350,3351
> "Q02353-1","2.8.2.-",""
> "Q02353-1","3.-.-.-",""
3347,3348d3391
< "D3ZJB8-1","2.3.2.31","[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine."
< "D3ZJB8-1","2.3.2.31",""
3353,3354d3395
< "P22734-1","2.1.1.6","S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol."
< "P22734-1","2.1.1.6",""
3362a3404,3405
> "Q9JJS8-1","3.4.21.104","Selective cleavage after Arg-223 in complement component C2 (-Ser-Leu-Gly-Arg-|-Lys-Ile-Gln-Ile) and after Arg-76 in complement component C4 (-Gly-Leu-Gln-Arg-|-Ala-Leu-Glu-Ile)."
> "Q9JJS8-1","3.4.21.104",""
3372a3416,3417
> "A0A1W2Q693-1","2.8.1.9","Molybdenum cofactor + L-cysteine + reduced acceptor + 2 H(+) = thio-molybdenum cofactor + L-alanine + H(2)O + oxidized acceptor."
> "A0A1W2Q693-1","2.8.1.9",""
3455a3501,3502
> "P25114-1","2.7.1.105","ATP + D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate."
> "P25114-1","3.1.3.46","Beta-D-fructose 2,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate."
3664,3665c3711,3712
< "F1LUT4-1","7.6.2.1","ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)."
< "F1LUT4-1","7.6.2.1",""
---
> "Q5CZZ9-1","2.7.1.68","ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."
> "Q5CZZ9-1","2.7.1.68",""
3671a3719,3722
> "D3ZEB9-1","2.1.1.43","S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]."
> "D3ZEB9-1","2.1.1.43",""
> "P97608-1","3.5.2.9","ATP + 5-oxo-L-proline + 2 H(2)O = ADP + phosphate + L-glutamate."
> "P97608-1","3.5.2.9",""
3691a3743,3744
> "Q9EQY6-1","2.4.1.-",""
> "Q9EQY6-1","2.4.1.-",""
3982,3983c4035,4036
< "Q80VJ4-1","3.1.4.2","sn-glycero-3-phosphocholine + H(2)O = choline + sn-glycerol 3-phosphate."
< "Q80VJ4-1","3.1.4.2",""
---
> "Q4V8J2-1","2.3.2.23","S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine."
> "Q4V8J2-1","2.3.2.23",""
4101a4155,4156
> "D3ZFC5-1","7.6.2.1","ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)."
> "D3ZFC5-1","7.6.2.1",""
4117a4173,4174
> "Q63321-1","1.14.11.4","L-lysine-[procollagen] + 2-oxoglutarate + O(2) = (2S,5R)-5-hydroxy-L-lysine-[procollagen] + succinate + CO(2)."
> "Q63321-1","1.14.11.4",""
4249,4250d4305
< "D3ZEB9-1","2.1.1.43","S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]."
< "D3ZEB9-1","2.1.1.43",""
4252a4308,4309
> "P80201-1","2.7.11.30","ATP + [receptor-protein] = ADP + [receptor-protein] phosphate."
> "P80201-1","2.7.11.30",""
4263,4264d4319
< "P97608-1","3.5.2.9","ATP + 5-oxo-L-proline + 2 H(2)O = ADP + phosphate + L-glutamate."
< "P97608-1","3.5.2.9",""
4322,4323c4377,4378
< "Q63707-1","1.3.5.2","(S)-dihydroorotate + a quinone = orotate + a quinol."
< "Q63707-1","1.3.5.2",""
---
> "D3ZG52-1","3.1.-.-",""
> "D3ZG52-1","3.6.4.12","ATP + H(2)O = ADP + phosphate."
4329a4385,4386
> "Q64568-1","7.2.2.10","ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)."
> "Q64568-1","7.2.2.10",""
4399a4457,4458
> "Q9JHW0-1","3.4.25.1","Cleavage of peptide bonds with very broad specificity."
> "Q9JHW0-1","3.4.25.1",""
4407a4467,4468
> "D3ZUA0-1","3.5.4.9","5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate."
> "D3ZUA0-1","1.5.1.15","5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH."
4455a4517,4518
> "Q99P84-1","3.1.4.11","1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol."
> "Q99P84-1","3.1.4.11",""
4489a4553,4554
> "D4A8L5-1","2.7.7.80","ATP + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP."
> "D4A8L5-1","2.8.1.11","[Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine + reduced acceptor = AMP + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + [cysteine desulfurase] + oxidized acceptor."
4612a4678,4679
> "P22734-1","2.1.1.6","S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol."
> "P22734-1","2.1.1.6",""
4809a4877,4880
> "P61131-1","2.4.99.2","CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R = CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R."
> "P61131-1","2.4.99.4","CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R."
> "P61131-1","2.4.99.4",""
> "P61131-1","2.4.99.2",""
4812a4884,4885
> "Q32Q05-1","3.4.19.12","Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)."
> "Q32Q05-1","3.4.19.12",""
4843a4917,4918
> "Q60587-1","2.3.1.16","Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA."
> "Q60587-1","2.3.1.155","Myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA."
4873,4874d4947
< "P16453-1","4.1.1.22","L-histidine = histamine + CO(2)."
< "P16453-1","4.1.1.22",""
4921,4922d4993
< "B2GV06-1","2.8.3.5","Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA."
< "B2GV06-1","2.8.3.5",""
4935,4936d5005
< "D4A5A6-1","2.7.7.6","Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)."
< "D4A5A6-1","2.7.7.6",""
5018a5088,5089
> "O08617-1","3.1.3.48","Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate."
> "O08617-1","3.1.3.48",""
5065a5137
> "P11497-1","6.3.4.14","ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine."
5091a5164,5168
> "P12785-1","1.1.1.100","(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH."
> "P12785-1","1.3.1.39","An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH."
> "P12785-1","2.3.1.38","Acetyl-CoA + [acyl-carrier-protein] = CoA + acetyl-[acyl-carrier-protein]."
> "P12785-1","2.3.1.39","Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein]."
> "P12785-1","2.3.1.41","Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO(2) + [acyl-carrier-protein]."
5092a5170,5171
> "P12785-1","3.1.2.14","Oleoyl-[acyl-carrier-protein] + H(2)O = [acyl-carrier-protein] + oleate."
> "P12785-1","4.2.1.59","A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl-carrier protein] + H(2)O."
5113c5192,5194
< "Q3MHS3-1","1.1.1.62","17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H."
---
> "Q64611-1","4.1.1.29","3-sulfino-L-alanine = hypotaurine + CO(2)."
> "Q64611-1","4.1.1.11","L-aspartate = beta-alanine + CO(2)."
> "Q64611-1","4.1.1.29",""
5172a5254,5255
> "Q924C3-1","3.1.4.1","Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides."
> "Q924C3-1","3.6.1.9","A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate."
5177a5261,5262
> "F1LUT4-1","7.6.2.1","ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)."
> "F1LUT4-1","7.6.2.1",""
5194,5195d5278
< "Q4V8J2-1","2.3.2.23","S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine."
< "Q4V8J2-1","2.3.2.23",""
5222a5306,5307
> "P19836-1","2.7.7.15","CTP + phosphocholine = diphosphate + CDP-choline."
> "P19836-1","2.7.7.15",""
5365a5451,5452
> "B2GV06-1","2.8.3.5","Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA."
> "B2GV06-1","2.8.3.5",""
5404,5405d5490
< "Q63321-1","1.14.11.4","L-lysine-[procollagen] + 2-oxoglutarate + O(2) = (2S,5R)-5-hydroxy-L-lysine-[procollagen] + succinate + CO(2)."
< "Q63321-1","1.14.11.4",""
5429a5515,5517
> "G3V918-1","2.1.2.2","10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide."
> "G3V918-1","6.3.3.1","ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole."
> "G3V918-1","6.3.4.13","ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)-(5-phospho-D-ribosyl)glycinamide."
5490a5579,5580
> "Q63484-1","2.7.11.1","ATP + a protein = ADP + a phosphoprotein."
> "Q63484-1","2.7.11.1",""
5568a5659,5660
> "Q80VJ4-1","3.1.4.2","sn-glycero-3-phosphocholine + H(2)O = choline + sn-glycerol 3-phosphate."
> "Q80VJ4-1","3.1.4.2",""
5573,5574c5665,5668
< "A0A1W2Q693-1","2.8.1.9","Molybdenum cofactor + L-cysteine + reduced acceptor + 2 H(+) = thio-molybdenum cofactor + L-alanine + H(2)O + oxidized acceptor."
< "A0A1W2Q693-1","2.8.1.9",""
---
> "P56558-1","2.4.1.255","UDP-N-acetyl-alpha-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine."
> "P56558-1","2.4.1.255",""
> "P23739-1","3.2.1.10","Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose."
> "P23739-1","3.2.1.48","Hydrolysis of sucrose and maltose by an alpha-D-glucosidase-type action."
5585,5586d5678
< "P19836-1","2.7.7.15","CTP + phosphocholine = diphosphate + CDP-choline."
< "P19836-1","2.7.7.15",""
5622,5623c5714,5715
< "Q9EQY6-1","2.4.1.-",""
< "Q9EQY6-1","2.4.1.-",""
---
> "O70249-1","4.2.99.18","The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate."
> "O70249-1","3.2.2.-",""
5709,5710d5800
< "Q920R3-1","1.14.19.44","(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = arachidonoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O."
< "Q920R3-1","1.14.19.44",""
5717,5718d5806
< "Q63450-1","2.7.11.17","ATP + a protein = ADP + a phosphoprotein."
< "Q63450-1","2.7.11.17",""
5754a5843,5844
> "Q03555-1","2.10.1.1","Adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP."
> "Q03555-1","2.7.7.75","ATP + molybdopterin = diphosphate + adenylyl-molybdopterin."
5815a5906
> "Q3MHS3-1","1.1.1.62","17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H."
5951a6043,6044
> "D3ZJB8-1","2.3.2.31","[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine."
> "D3ZJB8-1","2.3.2.31",""