{
    "uniprot_canonical_ac": "A0A0A0MS02-1", 
    "sequence": {
        "length": 117, 
        "sequence": "MRWALAVLLAFLSPASQISSNLEGRTKSVTRLTGSSAEITCDLPGASTLYIHWYLHQEGKAPQCLLYYEPYYSRVVLESGITPGKYDTGSTRSNWNLRLQNLIKNDSGFYYCATWDR"
    }, 
    "uniprot_id": "A0A0A0MS02_HUMAN", 
    "enzyme_annotation": [], 
    "alternativenames": [], 
    "keywords": [], 
    "species": [
        {
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0A0MS02", 
                    "id": "A0A0A0MS02", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "recommendedname": {}, 
    "publication": [], 
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        {
            "start_pos": 117, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A0A0MS02", 
                    "id": "A0A0A0MS02", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.0200", 
            "annotation": "Somatic mutation in Thyroid cancer (DOID:1781) with frequency of 1/50 (0.0200)", 
            "sequence_org": "R", 
            "disease": {
                "doid": "1781", 
                "url": "http://disease-ontology.org/term/DOID:1781", 
                "icd10": "", 
                "name": "Thyroid cancer"
            }, 
            "sequence_mut": "G", 
            "subjects_tested": "50", 
            "end_pos": 117, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 14, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A0A0MS02", 
                    "id": "A0A0A0MS02", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.0263", 
            "annotation": "Somatic mutation in Lung cancer (DOID:1324) with frequency of 1/38 (0.0263)", 
            "sequence_org": "P", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "T", 
            "subjects_tested": "38", 
            "end_pos": 14, 
            "type": "Point mutation"
        }, 
        {
            "start_pos": 2, 
            "subjects_positive": "1", 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A0A0MS02", 
                    "id": "A0A0A0MS02", 
                    "database": "BioMuta"
                }
            ], 
            "frequency": "0.0263", 
            "annotation": "Somatic mutation in Lung cancer (DOID:1324) with frequency of 1/38 (0.0263)", 
            "sequence_org": "R", 
            "disease": {
                "doid": "1324", 
                "url": "http://disease-ontology.org/term/DOID:1324", 
                "icd10": "", 
                "name": "Lung cancer"
            }, 
            "sequence_mut": "L", 
            "subjects_tested": "38", 
            "end_pos": 2, 
            "type": "Point mutation"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0A0MS02#A0A0A0MS02-1", 
            "isoform_ac": "A0A0A0MS02-1", 
            "locus": {
                "end_pos": 38367586, 
                "start_pos": 38368055, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000390348", 
                        "id": "ENST00000390348", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000374871", 
                        "id": "ENSP00000374871", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "length": 117, 
                "sequence": "MRWALAVLLAFLSPASQISSNLEGRTKSVTRLTGSSAEITCDLPGASTLYIHWYLHQEGKAPQCLLYYEPYYSRVVLESGITPGKYDTGSTRSNWNLRLQNLIKNDSGFYYCATWDR"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A0A6YYE8-1", 
            "protein_name": "", 
            "sequence": {
                "length": 116, 
                "sequence": "MLWALALLLAFLPAGRQTSSNLEERIMSITKLEGSSAIMTCDTHRTGTYIHWYRFQKGRAPEHLLYYNFVSSTTVVDSRFNLEKYHVYEGPDKRYKFVLRNVEESDSALYYCASWA"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0A0MS02/", 
                    "id": "A0A0A0MS02", 
                    "database": "OMA"
                }
            ], 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "refseq": {
        "url": "", 
        "ac": "", 
        "name": "", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0A0MS02", 
                                "id": "A0A0A0MS02", 
                                "database": "UniProtKB"
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                        ], 
                        "name": "external side of plasma membrane", 
                        "id": "GO:0009897"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 107, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 105
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000211701", 
            "id": "ENSG00000211701", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12284", 
            "id": "12284", 
            "database": "HGNC"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/LKICLWL/", 
            "id": "LKICLWL", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", 
            "id": "IPR007110", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", 
            "id": "IPR013783", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", 
            "id": "IPR036179", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", 
            "id": "IPR013106", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRGV1", 
            "id": "TRGV1", 
            "database": "GeneCards"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07686", 
            "id": "PF07686", 
            "database": "Pfam"
        }
    ], 
    "expression_disease": [], 
    "uniprot_ac": "A0A0A0MS02", 
    "disease": [], 
    "mass": {
        "monoisotopic_mass": 13248.0, 
        "chemical_mass": 13248.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12284", 
            "name": "TRGV1", 
            "locus": {
                "end_pos": 38367586, 
                "start_pos": 38368169, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000211701", 
                        "id": "ENSG00000211701", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ]
}