2c2,5
< "A0A0B4J1F4-1","19605364","Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins.","The Journal of biological chemistry","2009 Sep 11","Patwari P, Chutkow WA, Cummings K, Verstraeten VL, Lammerding J, Schreiter ER, Lee RT"
---
> "Q5F2L2-1","23986452","The Lewis X-related alpha1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations.","The Journal of biological chemistry","2013 Oct 4","Kumar A, Torii T, Ishino Y, Muraoka D, Yoshimura T, Togayachi A, Narimatsu H, Ikenaka K, Hitoshi S"
> "Q8VBV4-2","29633504","FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy.","Molecular oncology","2018 Jun","Xiao Y, Yin C, Wang Y, Lv H, Wang W, Huang Y, Perez-Losada J, Snijders AM, Mao JH, Zhang P"
> "Q8VBV4-2","29475832","Hepatic F-Box Protein FBXW7 Maintains Glucose Homeostasis Through Degradation of Fetuin-A.","Diabetes","2018 May","Zhao J, Xiong X, Li Y, Liu X, Wang T, Zhang H, Jiao Y, Jiang J, Zhang H, Tang Q, Gao X, Li X, Lu Y, Liu B, Hu C, Li X"
> "Q8VBV4-2","29550488","Genetic Deletion of Fbw7 in the mouse intestinal epithelium aggravated dextran sodium sulfate-induced colitis by modulating the inflammatory response of NF-kappaB pathway.","Biochemical and biophysical research communications","2018 Apr 15","Li H, Liang Y, Lai X, Wang W, Zhang J, Chen S"
13a17
> "Q6GYP7-1","12200424","Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.","The Journal of biological chemistry","2002 Nov 8","Heng JI, Tan SS"
17c21,22
< "Q8BSN9-1","20869947","Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration.","Biochemical and biophysical research communications","2010 Oct 22","Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro JB, Adelmant GO, Marto JA, Rhee K, Tisdale S, Danial N, Benarafa C, Orduna A, Anderson P"
---
> "Q8BXR6-1","26310831","Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.","Journal of leukocyte biology","2015 Dec","Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE"
> "Q8BXR6-1","23892723","Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.","Nature immunology","2013 Sep","Yang S, Wang B, Humphries F, Jackson R, Healy ME, Bergin R, Aviello G, Hall B, McNamara D, Darby T, Quinlan A, Shanahan F, Melgar S, Fallon PG, Moynagh PN"
19a25,33
> "Q5EE38-1","30189268","High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype.","Gene","2018 Dec 30","Sucularli C, Thomas P, Kocak H, White JS, O'Connor BC, Keegan CE"
> "Q5EE38-1","29386102","The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action.","Cell reports","2018 Jan 30","Grill S, Tesmer VM, Nandakumar J"
> "Q5EE38-1","24469404","TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1.","Molecular and cellular biology","2014 Apr","Frescas D, de Lange T"
> "Q5EE38-1","24316971","Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.","The Journal of clinical investigation","2014 Jan","Jones M, Osawa G, Regal JA, Weinberg DN, Taggart J, Kocak H, Friedman A, Ferguson DO, Keegan CE, Maillard I"
> "Q5EE38-1","17632522","Telomere protection by mammalian Pot1 requires interaction with Tpp1.","Nature structural &amp; molecular biology","2007 Aug","Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, Ye JZ, Keegan CE, de Lange T, Hammer GD"
> "Q5EE38-1","15537664","Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.","Human molecular genetics","2005 Jan 1","Keegan CE, Hutz JE, Else T, Adamska M, Shah SP, Kent AE, Howes JM, Beamer WG, Hammer GD"
> "Q00420-1","25200183","A SIRT7-dependent acetylation switch of GABPbeta1 controls mitochondrial function.","Cell metabolism","2014 Nov 4","Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J"
> "Q00420-1","22862946","Targeting tetramer-forming GABPbeta isoforms impairs self-renewal of hematopoietic and leukemic stem cells.","Cell stem cell","2012 Aug 3","Yu S, Jing X, Colgan JD, Zhao DM, Xue HH"
> "Q00420-1","21944889","Naive CD4+ T cells of Peyer's patches produce more IL-6 than those of spleen in response to antigenic stimulation.","Immunology letters","2011 Dec 30","Hashiguchi M, Hachimura S, Ametani A, Sato T, Kojima H, Kumagai Y, Habu S, Kobata T, Kaminogawa S"
21a36
> "Q8BVZ5-1","16286016","IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines.","Immunity","2005 Nov","Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, Zurawski G, Moshrefi M, Qin J, Li X, Gorman DM, Bazan JF, Kastelein RA"
33a49
> "P53702-1","11668396","Analysis of Mid1, Hccs, Arhgap6, and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf) mutant mice.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Oct","Cormier TA, Prakash SK, Magner DB, Zoghbi HY, Van den Veyver IB"
39,42d54
< "Q8K3W0-2","28436570","Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2-Mediated Degradation of p53.","Stem cells (Dayton, Ohio)","2017 Jul","Jin F, Wang Y, Wang X, Wu Y, Wang X, Liu Q, Zhu Y, Liu E, Fan J, Wang Y"
< "Q8K3W0-2","27001068","BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence.","Scientific reports","2016 Mar 22","Shi W, Tang MK, Yao Y, Tang C, Chui YL, Lee KKH"
< "Q8K3W0-2","24395041","Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells.","Apoptosis : an international journal on programmed cell death","2014 May","Chui YL, Ma CH, Li W, Xu Z, Yao Y, Lin FK, Chan JY, Lee KK"
< "Q8K3W0-2","14565866","Expression of a conserved mouse stress-modulating gene, Bre: comparison with the human ortholog.","DNA and cell biology","2003 Aug","Ching AK, Li Q, Lim PL, Chan JY, Chui YL"
44,46c56,61
< "Q91V88-1","28842827","Nephronectin is Decreased in Metastatic Breast Carcinoma and Related to Metastatic Organs.","Pathology oncology research : POR","2018 Jul","Dilmac S, Erin N, Demir N, Tanriover G"
< "Q91V88-1","28345658","Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains.","Scientific reports","2017 Mar 27","Arai C, Yoshizaki K, Miyazaki K, Saito K, Yamada A, Han X, Funada K, Fukumoto E, Haruyama N, Iwamoto T, Takahashi I, Fukumoto S"
< "Q91V88-1","17537792","The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.","Development (Cambridge, England)","2007 Jul","Linton JM, Martin GR, Reichardt LF"
---
> "Q6P1G2-1","29166607","Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function.","Cell reports","2017 Nov 21","Zhou Z, Yang X, He J, Liu J, Wu F, Yu S, Liu Y, Lin R, Liu H, Cui Y, Zhou C, Wang X, Wu J, Cao S, Guo L, Lin L, Wang T, Peng X, Qiang B, Hutchins AP, Pei D, Chen J"
> "Q6P1G2-1","28319097","Long noncoding RNA lncKdm2b is required for ILC3 maintenance by initiation of Zfp292 expression.","Nature immunology","2017 May","Liu B, Ye B, Yang L, Zhu X, Huang G, Zhu P, Du Y, Wu J, Qin X, Chen R, Tian Y, Fan Z"
> "Q6P1G2-1","24856970","Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.","Cell","2014 Jun 5","Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LL, Ito S, Cooper S, Kondo K, Koseki Y, Ishikura T, Long HK, Sheahan TW, Brockdorff N, Kessler BM, Koseki H, Klose RJ"
> "Q6P1G2-1","21220025","Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.","Molecular and cellular neurosciences","2011 Mar","Fukuda T, Tokunaga A, Sakamoto R, Yoshida N"
> "Q6P1G2-1","18836456","The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b).","Nature structural &amp; molecular biology","2008 Nov","He J, Kallin EM, Tsukada Y, Zhang Y"
> "Q6P1G2-1","17296600","Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.","Molecular &amp; cellular proteomics : MCP","2007 May","Sanchez C, Sanchez I, Demmers JA, Rodriguez P, Strouboulis J, Vidal M"
47a63,64
> "Q8K1E6-1","26930515","Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions.","ACS chemical biology","2016 May 20","You C, Wang P, Nay SL, Wang J, Dai X, O'Connor TR, Wang Y"
> "Q61481-4","22012077","Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart.","Basic research in cardiology","2011 Nov","Miller CL, Cai Y, Oikawa M, Thomas T, Dostmann WR, Zaccolo M, Fujiwara K, Yan C"
48a66,69
> "P49919-1","30284969","Cellular localization of the cell cycle inhibitor Cdkn1c controls growth arrest of adult skeletal muscle stem cells.","eLife","2018 Oct 4","Mademtzoglou D, Asakura Y, Borok MJ, Alonso-Martin S, Mourikis P, Kodaka Y, Mohan A, Asakura A, Relaix F"
> "P49919-1","17517131","Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.","BMC developmental biology","2007 May 21","Andrews SC, Wood MD, Tunster SJ, Barton SC, Surani MA, John RM"
> "Q9R1T4-1","29400567","Regulatory network analysis of hypertension and hypotension microarray data from mouse model.","Clinical and experimental hypertension (New York, N.Y. : 1993)","2018","Zhu Y, Zhuo J, Li C, Wang Q, Liu X, Ye L"
> "Q9R1T4-1","28751190","Septin 6 regulates engraftment and lymphoid differentiation potential of murine long-term hematopoietic stem cells.","Experimental hematology","2017 Nov","Senger K, Marka G, Soller K, Sakk V, Florian MC, Geiger H"
53,56c74,78
< "Q8BGC0-1","24352707","Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior.","Brain structure &amp; function","2015 Mar","Hahn YK, Podhaizer EM, Farris SP, Miles MF, Hauser KF, Knapp PE"
< "Q8BGC0-1","15485897","FF domains of CA150 bind transcription and splicing factors through multiple weak interactions.","Molecular and cellular biology","2004 Nov","Smith MJ, Kulkarni S, Pawson T"
< "Q8CEC0-1","18621024","Tumor marker nucleoporin 88 kDa regulates nucleocytoplasmic transport of NF-kappaB.","Biochemical and biophysical research communications","2008 Sep 26","Takahashi N, van Kilsdonk JW, Ostendorf B, Smeets R, Bruggeman SW, Alonso A, van de Loo F, Schneider M, van den Berg WB, Swart GW"
< "Q8CEC0-1","18606815","Nucleoporin 88 (Nup88) is regulated by hypertonic stress in kidney cells to retain the transcription factor tonicity enhancer-binding protein (TonEBP) in the nucleus.","The Journal of biological chemistry","2008 Sep 5","Andres-Hernando A, Lanaspa MA, Rivard CJ, Berl T"
---
> "Q9WV69-1","27073223","Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia.","Blood","2016 Jul 7","Lu Y, Hanada T, Fujiwara Y, Nwankwo JO, Wieschhaus AJ, Hartwig J, Huang S, Han J, Chishti AH"
> "Q9WV69-1","23060452","Headpiece domain of dematin regulates calcium mobilization and signaling in platelets.","The Journal of biological chemistry","2012 Nov 30","Wieschhaus AJ, Le Breton GC, Chishti AH"
> "Q9WV69-1","21084299","Dematin, a component of the erythrocyte membrane skeleton, is internalized by the malaria parasite and associates with Plasmodium 14-3-3.","The Journal of biological chemistry","2011 Jan 14","Lalle M, Curra C, Ciccarone F, Pace T, Cecchetti S, Fantozzi L, Ay B, Breton CB, Ponzi M"
> "Q9JI90-1","24472305","RNF14 is a regulator of mitochondrial and immune function in muscle.","BMC systems biology","2014 Jan 29","Ingham AB, Osborne SA, Menzies M, Briscoe S, Chen W, Kongsuwan K, Reverter A, Jeanes A, Dalrymple BP, Wijffels G, Seymour R, Hudson NJ"
> "B5KM66-1","17660561","Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.","Genetics","2007 Sep","Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH"
59a82,84
> "Q4V9Z5-1","29979789","BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.","PloS one","2018","Causevic M, Dominko K, Malnar M, Vidatic L, Cermak S, Pigoni M, Kuhn PH, Colombo A, Havas D, Flunkert S, McDonald J, Gunnersen JM, Hutter-Paier B, Tahirovic S, Windisch M, Krainc D, Lichtenthaler SF, Hecimovic S"
> "Q4V9Z5-1","29032200","Sez6l2 regulates phosphorylation of ADD and neuritogenesis.","Biochemical and biophysical research communications","2017 Dec 9","Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S"
> "Q4V9Z5-1","19242545","Association and mutation analyses of 16p11.2 autism candidate genes.","PloS one","2009","Kumar RA, Marshall CR, Badner JA, Babatz TD, Mukamel Z, Aldinger KA, Sudi J, Brune CW, Goh G, Karamohamed S, Sutcliffe JS, Cook EH, Geschwind DH, Dobyns WB, Scherer SW, Christian SL"
61a87,88
> "Q9D3A9-1","28607172","Tweety-Homolog 1 Drives Brain Colonization of Gliomas.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Jul 19","Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, Solecki G, Deumelandt K, Kurz FT, Xie R, Weil S, Heil O, Thome C, Gommel M, Syed M, Haring P, Huber PE, Heiland S, Platten M, von Deimling A, Wick W, Winkler F"
> "Q9D3A9-1","20568244","Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development.","Developmental dynamics : an official publication of the American Association of Anatomists","2010 Aug","Kumada T, Yamanaka Y, Kitano A, Shibata M, Awaya T, Kato T, Okawa K, Abe T, Oshima N, Nakahata T, Heike T"
63,67d89
< "Q3UHN9-1","29688404","Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation.","Endocrinology","2018 Jun 1","Yin Y, Wang A, Feng L, Wang Y, Zhang H, Zhang I, Bany BM, Ma L"
< "Q3UHN9-1","29330473","Endothelial heparan sulfate deficiency reduces inflammation and fibrosis in murine diabetic nephropathy.","Laboratory investigation; a journal of technical methods and pathology","2018 Apr","Talsma DT, Katta K, Ettema MAB, Kel B, Kusche-Gullberg M, Daha MR, Stegeman CA, van den Born J, Wang L"
< "Q1ERP8-1","24376728","Dynamic changes in endothelial cell adhesion molecule nepmucin/CD300LG expression under physiological and pathological conditions.","PloS one","2013","Umemoto E, Takeda A, Jin S, Luo Z, Nakahogi N, Hayasaka H, Lee CM, Tanaka T, Miyasaka M"
< "Q1ERP8-1","18675811","Nepmucin/CLM-9, an Ig domain-containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration in vitro.","FEBS letters","2008 Sep 3","Jin S, Umemoto E, Tanaka T, Shimomura Y, Tohya K, Kunizawa K, Yang BG, Jang MH, Hirata T, Miyasaka M"
< "Q1ERP8-1","16754720","Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow.","The Journal of experimental medicine","2006 Jun 12","Umemoto E, Tanaka T, Kanda H, Jin S, Tohya K, Otani K, Matsutani T, Matsumoto M, Ebisuno Y, Jang MH, Fukuda M, Hirata T, Miyasaka M"
74,87c96,100
< "Q3UHD9-1","28404596","Tumor Necrosis Factor-alpha Promotes Phosphoinositide 3-Kinase Enhancer A and AMP-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle.","Diabetes","2017 Jul","Tse MCL, Herlea-Pana O, Brobst D, Yang X, Wood J, Hu X, Liu Z, Lee CW, Zaw AM, Chow BKC, Ye K, Chan CB"
< "Q3UHD9-1","28096359","alpha-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.","Proceedings of the National Academy of Sciences of the United States of America","2017 Jan 31","Kang SS, Zhang Z, Liu X, Manfredsson FP, He L, Iuvone PM, Cao X, Sun YE, Jin L, Ye K"
< "Q3UHD9-1","24449917","PIKE is essential for oligodendroglia development and CNS myelination.","Proceedings of the National Academy of Sciences of the United States of America","2014 Feb 4","Chan CB, Liu X, Zhao L, Liu G, Lee CW, Feng Y, Ye K"
< "Q3UHD9-1","20068140","Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.","Diabetes","2010 Apr","Chan CB, Liu X, Jung DY, Jun JY, Luo HR, Kim JK, Ye K"
< "Q3UHD9-1","18469807","Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B.","Nature cell biology","2008 Jun","Tang X, Jang SW, Okada M, Chan CB, Feng Y, Liu Y, Luo SW, Hong Y, Rama N, Xiong WC, Mehlen P, Ye K"
< "O70546-1","30006524","UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma.","Nature communications","2018 Jul 13","Li X, Zhang Y, Zheng L, Liu M, Chen CD, Jiang H"
< "Q9D6Y7-1","29649787","Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription.","Redox biology","2018 Jun","Pennington SM, Klutho PR, Xie L, Broadhurst K, Koval OM, McCormick ML, Spitz DR, Grumbach IM"
< "Q9D6Y7-1","29929200","Methionine Sulfoxide Reductase A Knockout Mice Show Progressive Hearing Loss and Sensitivity to Acoustic Trauma.","Audiology &amp; neuro-otology","2018","Alqudah S, Chertoff M, Durham D, Moskovitz J, Staecker H, Peppi M"
< "Q9D6Y7-1","28803836","Methionine sulfoxide reductase A protects against lipopolysaccharide-induced septic shock via negative regulation of the proinflammatory responses.","Archives of biochemistry and biophysics","2017 Oct 1","Singh MP, Kim KY, Kwak GH, Baek SH, Kim HY"
< "Q9D6Y7-1","28442342","Methionine sulfoxide reductase A protects hepatocytes against acetaminophen-induced toxicity via regulation of thioredoxin reductase 1 expression.","Biochemical and biophysical research communications","2017 Jun 3","Singh MP, Kwak GH, Kim KY, Kim HY"
< "Q9D6Y7-1","15924425","Role of structural and functional elements of mouse methionine-S-sulfoxide reductase in its subcellular distribution.","Biochemistry","2005 Jun 7","Kim HY, Gladyshev VN"
< "Q9D6Y7-1","12792026","Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues.","Proceedings of the National Academy of Sciences of the United States of America","2003 Jun 24","Moskovitz J, Stadtman ER"
< "P05017-1","30915127","miR-29b-3p regulated osteoblast differentiation via regulating IGF-1 secretion of mechanically stimulated osteocytes.","Cellular &amp; molecular biology letters","2019","Zeng Q, Wang Y, Gao J, Yan Z, Li Z, Zou X, Li Y, Wang J, Guo Y"
< "P05017-1","30808767","Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration.","Proceedings of the National Academy of Sciences of the United States of America","2019 Feb 26","Pristera A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, Cragg S, Guillemot F, Ang SL"
---
> "Q8CIE4-1","30097860","Assessment of Intracellular Auto-Modification Levels of ARTD10 Using Mono-ADP-Ribose-Specific Macrodomains 2 and 3 of Murine Artd8.","Methods in molecular biology (Clifton, N.J.)","2018","Butepage M, Krieg S, Eckei L, Li J, Rossetti G, Verheugd P, Luscher B"
> "P56812-1","29588416","Programmed cell death 5 suppresses AKT-mediated cytoprotection of endothelium.","Proceedings of the National Academy of Sciences of the United States of America","2018 May 1","Lee SH, Seo J, Park SY, Jeong MH, Choi HK, Lee CJ, Kim MJ, Guk G, Lee S, Park H, Jeong JW, Ha CH, Park S, Yoon HG"
> "Q62158-1","29897614","Trim27 confers myeloid hematopoiesis competitiveness by up-regulating myeloid master genes.","Journal of leukocyte biology","2018 Oct","Wang T, Xia C, Dong Y, Chen X, Wang J, Du J"
> "Q9Z2Y3-1","12176012","An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.","Biochemical and biophysical research communications","2002 Aug 23","Saito H, Kimura M, Inanobe A, Ohe T, Kurachi Y"
> "Q9ET78-1","30867288","RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.","Proceedings of the National Academy of Sciences of the United States of America","2019 Mar 26","Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, Gou LT, Zhou Y, Zhang J, Ren S, Chen J, Wang Y, Fu XD"
92,96c105,106
< "Q99K48-1","29673854","Silencing of Non-POU-domain-containing octamer-binding protein stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice via NF-kappaB signaling pathway.","International journal of cardiology","2018 Jul 15","Zhang K, Zhang F, Yang JM, Kong J, Meng X, Zhang M, Zhang C, Zhang Y"
< "Q99K48-1","29358041","The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding.","Cell metabolism","2018 Feb 6","Benegiamo G, Mure LS, Erikson G, Le HD, Moriggi E, Brown SA, Panda S"
< "Q99K48-1","28209515","Cell-type specific role of the RNA-binding protein, NONO, in the DNA double-strand break response in the mouse testes.","DNA repair","2017 Mar","Li S, Shu FJ, Li Z, Jaafar L, Zhao S, Dynan WS"
< "Q91X46-1","28542600","SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume.","PloS one","2017","Zou S, Teixeira AM, Kostadima M, Astle WJ, Radhakrishnan A, Simon LM, Truman L, Fang JS, Hwa J, Zhang PX, van der Harst P, Bray PF, Ouwehand WH, Frontini M, Krause DS"
< "Q91X46-1","23192023","Structure of the Rho-specific guanine nucleotide-exchange factor Xpln.","Acta crystallographica. Section F, Structural biology and crystallization communications","2012 Dec 1","Murayama K, Kato-Murayama M, Akasaka R, Terada T, Yokoyama S, Shirouzu M"
---
> "Q9D424-1","27802166","CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa.","Journal of cell science","2016 Dec 1","Young SA, Miyata H, Satouh Y, Aitken RJ, Baker MA, Ikawa M"
> "Q9D424-1","20731842","CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.","Reproductive biology and endocrinology : RB&amp;E","2010 Aug 23","Li YF, He W, Kim YH, Mandal A, Digilio L, Klotz K, Flickinger CJ, Herr JC"
99a110
> "Q99JW4-1","25609703","The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites.","Journal of cell science","2015 Mar 1","Karakose E, Geiger T, Flynn K, Lorenz-Baath K, Zent R, Mann M, Fassler R"
104a116
> "Q8C0R7-1","20675388","Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility.","The Journal of biological chemistry","2010 Oct 8","Yan W, Si Y, Slaymaker S, Li J, Zheng H, Young DL, Aslanian A, Saunders L, Verdin E, Charo IF"
110,114d121
< "Q9JL26-1","28361956","Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage.","Nature communications","2017 Mar 31","Pfisterer SG, Gateva G, Horvath P, Pirhonen J, Salo VT, Karhinen L, Varjosalo M, Ryhanen SJ, Lappalainen P, Ikonen E"
< "Q9JL26-1","25447542","Formin mDia1, a downstream molecule of FMNL1, regulates Profilin1 for actin assembly and spindle organization during mouse oocyte meiosis.","Biochimica et biophysica acta","2015 Feb","Zhang Y, Wang F, Niu YJ, Liu HL, Rui R, Cui XS, Kim NH, Sun SC"
< "Q9JL26-1","26083584","RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.","Cell cycle (Georgetown, Tex.)","2015","Wang F, Zhang L, Duan X, Zhang GL, Wang ZB, Wang Q, Xiong B, Sun SC"
< "Q9JL26-1","16556604","Mechanistic differences in actin bundling activity of two mammalian formins, FRL1 and mDia2.","The Journal of biological chemistry","2006 May 19","Harris ES, Rouiller I, Hanein D, Higgs HN"
< "Q9JL26-1","16480715","Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.","Experimental cell research","2006 Apr 15","Zhou F, Leder P, Martin SS"
116a124
> "O35453-1","12962630","The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain.","Structure (London, England : 1993)","2003 Sep","Somoza JR, Ho JD, Luong C, Ghate M, Sprengeler PA, Mortara K, Shrader WD, Sperandio D, Chan H, McGrath ME, Katz BA"
117a126
> "Q9DBE0-1","26327310","Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.","Neurochemistry international","2015 Nov","Winge I, Teigen K, Fossbakk A, Mahootchi E, Kleppe R, Skoldberg F, Kampe O, Haavik J"
122a132,133
> "P97468-1","30576947","Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and beta-arrestin 2 in inflammatory macrophages.","Molecular immunology","2019 Feb","Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ"
> "P97468-1","29556954","Role of chemerin/CMKLR1 in the maintenance of early pregnancy.","Frontiers of medicine","2018 Oct","Yang X, Yao J, Wei Q, Ye J, Yin X, Quan X, Lan Y, Xing H"
127a139
> "Q810F8-1","20162674","A unique expression pattern of Tbx10 in the hindbrain as revealed by Tbx10(LacZ) allele.","Genesis (New York, N.Y. : 2000)","2010 May","Xue XD, Kimura W, Wang B, Hikosaka K, Itakura T, Uezato T, Matsuda M, Koseki H, Miura N"
130,131d141
< "Q3UPW2-1","27222093","E74-like factor 3 and nuclear factor-kappaB regulate lipocalin-2 expression in chondrocytes.","The Journal of physiology","2016 Nov 1","Conde J, Otero M, Scotece M, Abella V, Lopez V, Pino J, Gomez R, Lago F, Goldring MB, Gualillo O"
< "Q3UPW2-1","11893733","Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1.","The Journal of biological chemistry","2002 May 17","Kim JH, Wilder PJ, Hou J, Nowling T, Rizzino A"
137d146
< "Q6ZPE2-1","11994405","Male infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1.","The Journal of clinical investigation","2002 May","Firestein R, Nagy PL, Daly M, Huie P, Conti M, Cleary ML"
147,154c156
< "Q924Z6-1","22323606","Active maintenance of nuclear actin by importin 9 supports transcription.","Proceedings of the National Academy of Sciences of the United States of America","2012 Feb 28","Dopie J, Skarp KP, Rajakyla EK, Tanhuanpaa K, Vartiainen MK"
< "Q3UUY6-1","20333396","Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney.","Histochemistry and cell biology","2010 May","Jaszai J, Farkas LM, Fargeas CA, Janich P, Haase M, Huttner WB, Corbeil D"
< "Q3UUY6-1","18536929","Robust expression of Prominin-2 all along the adult male reproductive system and urinary bladder.","Histochemistry and cell biology","2008 Oct","Jaszai J, Fargeas CA, Haase M, Farkas LM, Huttner WB, Corbeil D"
< "Q3UUY6-1","17874118","Differential expression of Prominin-1 (CD133) and Prominin-2 in major cephalic exocrine glands of adult mice.","Histochemistry and cell biology","2007 Nov","Jaszai J, Janich P, Farkas LM, Fargeas CA, Huttner WB, Corbeil D"
< "Q3UUY6-1","17109118","Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine.","Cell and tissue research","2007 Apr","Florek M, Bauer N, Janich P, Wilsch-Braeuninger M, Fargeas CA, Marzesco AM, Ehninger G, Thiele C, Huttner WB, Corbeil D"
< "Q3UUY6-1","12514187","Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins.","The Journal of biological chemistry","2003 Mar 7","Fargeas CA, Florek M, Huttner WB, Corbeil D"
< "Q69ZW3-1","15247266","Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.","The Journal of biological chemistry","2004 Sep 17","Guilherme A, Soriano NA, Furcinitti PS, Czech MP"
< "Q69ZW3-1","14676205","EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.","The Journal of biological chemistry","2004 Mar 12","Guilherme A, Soriano NA, Bose S, Holik J, Bose A, Pomerleau DP, Furcinitti P, Leszyk J, Corvera S, Czech MP"
---
> "P29754-1","29990483","Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.","Life sciences","2018 Sep 1","Liu J, Chen Q, Liu S, Yang X, Zhang Y, Huang F"
160a163
> "O88932-1","22566534","Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes.","Diabetes","2012 Jul","Okamoto K, Iwasaki N, Doi K, Noiri E, Iwamoto Y, Uchigata Y, Fujita T, Tokunaga K"
162,165c165
< "Q8BJS4-1","29995584","A molecular model for LINC complex regulation: activation of SUN2 for KASH binding.","Molecular biology of the cell","2018 Aug 8","Jahed Z, Vu UT, Fadavi D, Ke H, Rathish A, Kim SCJ, Feng W, Mofrad MRK"
< "Q8BJS4-1","19509342","SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.","Proceedings of the National Academy of Sciences of the United States of America","2009 Jun 23","Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M"
< "Q8BJS4-1","17452644","Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope.","Proceedings of the National Academy of Sciences of the United States of America","2007 May 1","Schmitt J, Benavente R, Hodzic D, Hoog C, Stewart CL, Alsheimer M"
< "Q8BJS4-1","17132086","Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome.","DNA and cell biology","2006 Oct","Wang Q, Du X, Cai Z, Greene MI"
---
> "Q8BFZ9-1","30135210","The erlin2 T65I mutation inhibits erlin1/2 complex-mediated inositol 1,4,5-trisphosphate receptor ubiquitination and phosphatidylinositol 3-phosphate binding.","The Journal of biological chemistry","2018 Oct 5","Wright FA, Bonzerato CG, Sliter DA, Wojcikiewicz RJH"
168a169
> "Q8BGW8-1","14762206","VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation.","Nucleic acids research","2004","Gunther S, Mielcarek M, Kruger M, Braun T"
173,176d173
< "Q70IV5-1","25567810","Myopathic changes in murine skeletal muscle lacking synemin.","American journal of physiology. Cell physiology","2015 Mar 15","Garcia-Pelagio KP, Muriel J, O'Neill A, Desmond PF, Lovering RM, Lund L, Bond M, Bloch RJ"
< "Q70IV5-1","17654553","Synemin expression in brain.","Muscle &amp; nerve","2007 Oct","Mizuno Y, Guyon JR, Okamoto K, Kunkel LM"
< "Q70IV5-1","17356066","Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.","Journal of cell science","2007 Apr 1","Jing R, Wilhelmsson U, Goodwill W, Li L, Pan Y, Pekny M, Skalli O"
< "Q70IV5-1","16817202","Different expression of synemin isoforms in glia and neurons during nervous system development.","Glia","2006 Aug 15","Izmiryan A, Cheraud Y, Khanamiryan L, Leterrier JF, Federici T, Peltekian E, Moura-Neto V, Paulin D, Li Z, Xue ZG"
177a175,177
> "O08575-1","30628662","Eya2 is critical for the E2AHLFmediated immortalization of mouse hematopoietic stem/progenitor cells.","International journal of oncology","2019 Mar","Maharjan BD, Ono R, Nosaka T"
> "P35377-1","26294734","Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice.","Haematologica","2015 Dec","Vang D, Paul JA, Nguyen J, Tran H, Vincent L, Yasuda D, Zaveri NT, Gupta K"
> "P35377-1","26290245","Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Aug 19","Ozawa A, Brunori G, Mercatelli D, Wu J, Cippitelli A, Zou B, Xie XS, Williams M, Zaveri NT, Low S, Scherrer G, Kieffer BL, Toll L"
181a182,183
> "P54254-1","30507379","Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1.","eLife","2018 Dec 3","Driessen TM, Lee PJ, Lim J"
> "P54254-1","29860311","PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.","Human molecular genetics","2018 Aug 15","Bondar VV, Adamski CJ, Onur TS, Tan Q, Wang L, Diaz-Garcia J, Park J, Orr HT, Botas J, Zoghbi HY"
186,188d187
< "Q61990-1","29422543","Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA.","Experimental &amp; molecular medicine","2018 Feb 9","Kim JK, Kim I, Choi K, Choi JH, Kim E, Lee HY, Park J, Kim Yoon S"
< "Q61990-1","27215387","Poly(rC)-Binding Protein 2 Regulates Hippo Signaling To Control Growth in Breast Epithelial Cells.","Molecular and cellular biology","2016 Aug 15","Li F, Bullough KZ, Vashisht AA, Wohlschlegel JA, Philpott CC"
< "Q61990-1","26907686","RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant Defense.","The Journal of biological chemistry","2016 Apr 29","Ren C, Zhang J, Yan W, Zhang Y, Chen X"
203c202,207
< "Q99N48-1","11773082","The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.","The Journal of biological chemistry","2002 Mar 15","Kuroda TS, Fukuda M, Ariga H, Mikoshiba K"
---
> "Q920Q2-1","28498946","Overexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1 expression level.","Carcinogenesis","2017 May 1","Sasatani M, Xi Y, Kajimura J, Kawamura T, Piao J, Masuda Y, Honda H, Kubo K, Mikamoto T, Watanabe H, Xu Y, Kawai H, Shimura T, Noda A, Hamasaki K, Kusunoki Y, Zaharieva EK, Kamiya K"
> "Q60611-1","29442043","Satb1 promotes osteoclastogenesis by recruiting CBP to upregulate miR-223 expression in chronic kidney disease-mineral and bone disorder.","Die Pharmazie","2017 Nov 1","Li J, Xing G, Zhang L, Shang J, Li Y, Li C, Tian F, Yang X"
> "P62881-1","28687610","Regulator of G-protein signaling Gbeta5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2017 Nov","Wang Q, Pronin AN, Levay K, Almaca J, Fornoni A, Caicedo A, Slepak VZ"
> "Q6ZPQ6-1","26269578","RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells.","Molecular biology of the cell","2015 Oct 15","Walker MT, Rupp A, Elsaesser R, Guler AD, Sheng W, Weng S, Berson DM, Hattar S, Montell C"
> "Q8BHJ5-1","28612505","SET domain-containing protein 5 is required for expression of primordial germ cell specification-associated genes in murine embryonic stem cells.","Cell biochemistry and function","2017 Jul","Yu SE, Kim MS, Park SH, Yoo BC, Kim KH, Jang YK"
> "Q8BHJ5-1","14980219","A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.","Cell","2004 Feb 20","Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG"
206a211,213
> "Q9R0Y5-1","24740601","Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm.","Biology of reproduction","2014 Jun","Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL"
> "Q9R0Y5-1","23447692","CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation.","Journal of immunology (Baltimore, Md. : 1950)","2013 Apr 1","Guo L, Stripay JL, Zhang X, Collage RD, Hulver M, Carchman EH, Howell GM, Zuckerbraun BS, Lee JS, Rosengart MR"
> "Q8K1H1-1","21436445","Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.","Science (New York, N.Y.)","2011 Mar 25","Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL"
209a217
> "Q9CQX0-1","23515685","Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets.","Diabetologia","2013 Jun","Beck A, Vinik Y, Shatz-Azoulay H, Isaac R, Streim S, Jona G, Boura-Halfon S, Zick Y"
215a224,228
> "Q9R194-1","29466738","Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b.","Cell reports","2018 Feb 20","Lowe M, Lage J, Paatela E, Munson D, Hostager R, Yuan C, Katoku-Kikyo N, Ruiz-Estevez M, Asakura Y, Staats J, Qahar M, Lohman M, Asakura A, Kikyo N"
> "Q8K3W0-2","28436570","Bre Enhances Osteoblastic Differentiation by Promoting the Mdm2-Mediated Degradation of p53.","Stem cells (Dayton, Ohio)","2017 Jul","Jin F, Wang Y, Wang X, Wu Y, Wang X, Liu Q, Zhu Y, Liu E, Fan J, Wang Y"
> "Q8K3W0-2","27001068","BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence.","Scientific reports","2016 Mar 22","Shi W, Tang MK, Yao Y, Tang C, Chui YL, Lee KKH"
> "Q8K3W0-2","24395041","Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells.","Apoptosis : an international journal on programmed cell death","2014 May","Chui YL, Ma CH, Li W, Xu Z, Yao Y, Lin FK, Chan JY, Lee KK"
> "Q8K3W0-2","14565866","Expression of a conserved mouse stress-modulating gene, Bre: comparison with the human ortholog.","DNA and cell biology","2003 Aug","Ching AK, Li Q, Lim PL, Chan JY, Chui YL"
217a231,232
> "Q6P5C5-1","28775312","Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.","Scientific reports","2017 Aug 3","Alsoe L, Sarno A, Carracedo S, Domanska D, Dingler F, Lirussi L, SenGupta T, Tekin NB, Jobert L, Alexandrov LB, Galashevskaya A, Rada C, Sandve GK, Rognes T, Krokan HE, Nilsen H"
> "Q6P5C5-1","12820976","Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1.","Molecular cell","2003 Jun","Wibley JE, Waters TR, Haushalter K, Verdine GL, Pearl LH"
220a236
> "Q9JIB0-1","18184654","Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5.","The Journal of biological chemistry","2008 Mar 14","Wu L, Yong SL, Fan C, Ni Y, Yoo S, Zhang T, Zhang X, Obejero-Paz CA, Rho HJ, Ke T, Szafranski P, Jones SW, Chen Q, Wang QK"
222a239,242
> "Q60700-1","28641113","Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.","Neuron","2017 Jun 21","Welsbie DS, Mitchell KL, Jaskula-Ranga V, Sluch VM, Yang Z, Kim J, Buehler E, Patel A, Martin SE, Zhang PW, Ge Y, Duan Y, Fuller J, Kim BJ, Hamed E, Chamling X, Lei L, Fraser IDC, Ronai ZA, Berlinicke CA, Zack DJ"
> "Q62048-1","29928894","High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle.","Metabolism: clinical and experimental","2018 Oct","Vastolo V, Nettore IC, Ciccarelli M, Albano L, Raciti GA, Longo M, Beguinot F, Ungaro P"
> "Q62048-1","27426254","Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice.","Scientific reports","2016 Jul 18","Perruolo G, Viggiano D, Fiory F, Cassese A, Nigro C, Liotti A, Miele C, Beguinot F, Formisano P"
> "Q62048-1","19917132","Deletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities.","BMC neuroscience","2009 Nov 16","Ramos JW, Townsend DA, Piarulli D, Kolata S, Light K, Hale G, Matzel LD"
223a244,253
> "Q91W10-1","28481222","Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.","The Journal of clinical investigation","2017 Jun 1","Lin W, Vann DR, Doulias PT, Wang T, Landesberg G, Li X, Ricciotti E, Scalia R, He M, Hand NJ, Rader DJ"
> "Q91W10-1","28057442","Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels.","Experimental eye research","2017 Feb","Sterling J, Guttha S, Song Y, Song D, Hadziahmetovic M, Dunaief JL"
> "Q91W10-1","17108009","Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.","American journal of physiology. Cell physiology","2007 Apr","Wang B, Schneider SN, Dragin N, Girijashanker K, Dalton TP, He L, Miller ML, Stringer KF, Soleimani M, Richardson DD, Nebert DW"
> "Q8BG60-1","30138646","Increased thioredoxin-interacting protein in brain of mice exposed to chronic stress.","Progress in neuro-psychopharmacology &amp; biological psychiatry","2019 Jan 10","Zhou H, Tan H, Letourneau L, Wang JF"
> "Q8BG60-1","30142540","TXNIP mediated the oxidative stress response in glomerular mesangial cells partially through AMPK pathway.","Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie","2018 Nov","Xu W, Wang L, Li J, Cai Y, Xue Y"
> "Q8BG60-1","29884908","Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.","Laboratory investigation; a journal of technical methods and pathology","2018 Sep","Wu M, Li R, Hou Y, Song S, Han W, Chen N, Du Y, Ren Y, Shi Y"
> "Q4FZC9-1","23761073","Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis.","Molecular biology of the cell","2013 Aug","Ketema M, Kreft M, Secades P, Janssen H, Sonnenberg A"
> "Q4FZC9-1","23336069","The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction.","Scientific reports","2013","Chambliss AB, Khatau SB, Erdenberger N, Robinson DK, Hodzic D, Longmore GD, Wirtz D"
> "Q4FZC9-1","17881500","Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin.","Journal of cell science","2007 Oct 1","Ketema M, Wilhelmsen K, Kuikman I, Janssen H, Hodzic D, Sonnenberg A"
> "Q4FZC9-1","16330710","Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.","The Journal of cell biology","2005 Dec 5","Wilhelmsen K, Litjens SH, Kuikman I, Tshimbalanga N, Janssen H, van den Bout I, Raymond K, Sonnenberg A"
229,231c259
< "O08785-1","30530698","Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.","Proceedings of the National Academy of Sciences of the United States of America","2018 Dec 26","Qu M, Duffy T, Hirota T, Kay SA"
< "O08785-1","30124738","Circadian locomotor output cycles kaput accelerates atherosclerotic plaque formation by upregulating plasminogen activator inhibitor-1 expression.","Acta biochimica et biophysica Sinica","2018 Sep 1","Jiang Q, Liu H, Wang S, Wang J, Tang Y, He Z, Wu F, Huang Z, Cong X, Ding R, Liang C"
< "O08785-1","30695595","[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].","Voprosy onkologii","2016","Gubareva EA, Maidin MA, Tyndyk ML, Vinogradova LA, Panchenko AV"
---
> "Q8CJC7-1","12782717","The lectin-like receptor KLRE1 inhibits natural killer cell cytotoxicity.","The Journal of experimental medicine","2003 Jun 2","Westgaard IH, Dissen E, Torgersen KM, Lazetic S, Lanier LL, Phillips JH, Fossum S"
235a264,268
> "Q68FG0-1","30177510","Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains.","Development (Cambridge, England)","2018 Sep 3","Kim J, Choi TI, Park S, Kim MH, Kim CH, Lee S"
> "Q68FG0-1","28814648","ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus.","Open biology","2017 Aug","Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B"
> "Q68FG0-1","23623388","ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.","American journal of human genetics","2013 May 2","Hirata H, Nanda I, van Riesen A, McMichael G, Hu H, Hambrock M, Papon MA, Fischer U, Marouillat S, Ding C, Alirol S, Bienek M, Preisler-Adams S, Grimme A, Seelow D, Webster R, Haan E, MacLennan A, Stenzel W, Yap TY, Gardner A, Nguyen LS, Shaw M, Lebrun N, Haas SA, Kress W, Haaf T, Schellenberger E, Chelly J, Viot G, Shaffer LG, Rosenfeld JA, Kramer N, Falk R, El-Khechen D, Escobar LF, Hennekam R, Wieacker P, Hubner C, Ropers HH, Gecz J, Schuelke M, Laumonnier F, Kalscheuer VM"
> "Q6P8Y0-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
> "Q99PM3-1","25664857","Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.","The Journal of clinical investigation","2015 Mar 2","Takeda S, Sasagawa S, Oyama T, Searleman AC, Westergard TD, Cheng EH, Hsieh JJ"
239a273,276
> "Q62219-1","29242607","The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.","Oncogene","2018 Mar","Omoto T, Kim-Kaneyama JR, Lei XF, Orimo A, Ohnishi K, Yoshihara K, Miyauchi A, Li S, Gao L, Umemoto T, Tanaka J, Nakahara K, Takeya M, Ishida F, Kudo SE, Haraguchi S, Miyazaki T, Miyazaki A"
> "Q62219-1","27893716","Hic-5 remodeling of the stromal matrix promotes breast tumor progression.","Oncogene","2017 May 11","Goreczny GJ, Ouderkirk-Pecone JL, Olson EC, Krendel M, Turner CE"
> "Q62219-1","28139974","The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 alpha-enhancer activity.","eLife","2017 Jan 31","Kim Y, Lim S, Ha T, Song YH, Sohn YI, Park DJ, Paik SS, Kim-Kaneyama JR, Song MR, Leung A, Levine EM, Kim IB, Goo YS, Lee SH, Kang KH, Kim JW"
> "Q62219-1","27269065","Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.","The Journal of cell biology","2016 Jun 6","Petropoulos C, Oddou C, Emadali A, Hiriart-Bryant E, Boyault C, Faurobert E, Vande Pol S, Kim-Kaneyama JR, Kraut A, Coute Y, Block M, Albiges-Rizo C, Destaing O"
245a283
> "Q7TSA3-1","12796776","BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.","Nature immunology","2003 Jul","Watanabe N, Gavrieli M, Sedy JR, Yang J, Fallarino F, Loftin SK, Hurchla MA, Zimmerman N, Sim J, Zang X, Murphy TL, Russell JH, Allison JP, Murphy KM"
246a285,286
> "P61092-1","28843785","HIF-1alpha coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.","Biochimica et biophysica acta. Gene regulatory mechanisms","2017 Oct","Fan Z, Li Z, Yang Y, Liu S, Guo J, Xu Y"
> "P43006-1","29722912","Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice.","Glia","2018 Sep","Zhao Z, Hiraoka Y, Ogawa H, Tanaka K"
247a288,289
> "P67871-1","29483533","Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.","Nature communications","2018 Feb 26","Yang CP, Li X, Wu Y, Shen Q, Zeng Y, Xiong Q, Wei M, Chen C, Liu J, Huo Y, Li K, Xue G, Yao YG, Zhang C, Li M, Chen Y, Luo XJ"
> "Q9R0T8-1","30902986","Microbial recognition by GEF-H1 controls IKKepsilon mediated activation of IRF5.","Nature communications","2019 Mar 22","Zhao Y, Zagani R, Park SM, Yoshida N, Shah P, Reinecker HC"
248a291,294
> "Q60682-1","27831490","Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules.","The Biochemical journal","2017 Jan 1","Romasanta PN, Curto LM, Sarratea MB, Noli Truant S, Antonoglou MB, Fernandez Lynch MJ, Delfino JM, Mariuzza RA, Fernandez MM, Malchiodi EL"
> "Q6Q783-1","27920088","SUV4-20 activity in the preimplantation mouse embryo controls timely replication.","Genes &amp; development","2016 Nov 15","Eid A, Rodriguez-Terrones D, Burton A, Torres-Padilla ME"
> "Q6Q783-1","26904956","lncRNA-Induced Nucleosome Repositioning Reinforces Transcriptional Repression of rRNA Genes upon Hypotonic Stress.","Cell reports","2016 Mar 1","Zhao Z, Dammert MA, Grummt I, Bierhoff H"
> "Q6Q783-1","17846168","Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.","The Journal of cell biology","2007 Sep 10","Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA"
255,256d300
< "Q99JA4-1","29916540","Montelukast inhibits RANKLinduced osteoclast formation and bone loss via CysLTR1 and P2Y12.","Molecular medicine reports","2018 Aug","Kang JH, Lim H, Lee DS, Yim M"
< "Q99JA4-1","11932261","Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses.","The Journal of biological chemistry","2002 Jun 7","Maekawa A, Austen KF, Kanaoka Y"
263a308
> "Q3U3C9-1","16169686","Temporal change in mKIAA gene expression during the early stage of retinoic acid-induced neurite outgrowth.","Gene","2005 Dec 30","Imai K, Kawai M, Tada M, Nagase T, Ohara O, Koga H"
267a313,314
> "Q91Z31-1","29045475","Association between RNA-binding protein Ptbp2 and germ cell injury in an experimentally-induced unilateral cryptorchidism murine model.","PloS one","2017","Dou X, Gao J, Gao P, Tang D, Peng D, Mao J, Huang Z, Chen P, Chen H, Ke S, Liang C, Zhang X"
> "Q91Z31-1","10829067","A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing.","Proceedings of the National Academy of Sciences of the United States of America","2000 Jun 6","Polydorides AD, Okano HJ, Yang YY, Stefani G, Darnell RB"
278,282d324
< "Q80U58-1","29046322","Pumilio2-deficient mice show a predisposition for epilepsy.","Disease models &amp; mechanisms","2017 Nov 1","Follwaczny P, Schieweck R, Riedemann T, Demleitner A, Straub T, Klemm AH, Bilban M, Sutor B, Popper B, Kiebler MA"
< "Q80U58-1","28794184","Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.","Genes &amp; development","2017 Jul 1","Zhang M, Chen D, Xia J, Han W, Cui X, Neuenkirchen N, Hermes G, Sestan N, Lin H"
< "O08532-1","30355732","The alpha2delta-1-NMDA receptor coupling is essential for corticostriatal long-term potentiation and is involved in learning and memory.","The Journal of biological chemistry","2018 Dec 14","Zhou JJ, Li DP, Chen SR, Luo Y, Pan HL"
< "O08532-1","16460711","Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice.","Brain research","2006 Feb 23","Bian F, Li Z, Offord J, Davis MD, McCormick J, Taylor CP, Walker LC"
< "O08532-1","1847144","Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides.","The Journal of biological chemistry","1991 Feb 15","Jay SD, Sharp AH, Kahl SD, Vedvick TS, Harpold MM, Campbell KP"
286a329,331
> "P08923-1","22079349","Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis.","Pharmacology, biochemistry, and behavior","2012 Jan","Weiss JB, Xue C, Benice T, Xue L, Morris SW, Raber J"
> "P08923-1","18854310","Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis.","The Journal of biological chemistry","2008 Dec 5","Li J, Niu XL, Madamanchi NR"
> "P08923-1","2357970","The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator.","The EMBO journal","1990 Jul","Bernards A, de la Monte SM"
303a349,350
> "Q7TSY8-1","28781233","Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis.","Molecular cell","2017 Aug 17","Krishnan S, Smits AH, Vermeulen M, Reinberg D"
> "Q7TSY8-1","27629923","Mutations of SGO2 and CLDN14 collectively cause coincidental Perrault syndrome.","Clinical genetics","2017 Feb","Faridi R, Rehman AU, Morell RJ, Friedman PL, Demain L, Zahra S, Khan AA, Tohlob D, Assir MZ, Beaman G, Khan SN, Newman WG, Riazuddin S, Friedman TB"
306,307c353
< "Q3UUJ4-1","21903876","Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle.","Journal of applied physiology (Bethesda, Md. : 1985)","2011 Dec","Smith CD, Compton RA, Bowler JS, Kemp JT, Sudweeks SN, Thomson DM, Winder WW"
< "Q3UUJ4-1","20424326","STRADalpha deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice.","The Journal of clinical investigation","2010 May","Orlova KA, Parker WE, Heuer GG, Tsai V, Yoon J, Baybis M, Fenning RS, Strauss K, Crino PB"
---
> "Q99K51-1","30204862","Plastin 3 influences bone homeostasis through regulation of osteoclast activity.","Human molecular genetics","2018 Dec 15","Neugebauer J, Heilig J, Hosseinibarkooie S, Ross BC, Mendoza-Ferreira N, Nolte F, Peters M, Holker I, Hupperich K, Tschanz T, Grysko V, Zaucke F, Niehoff A, Wirth B"
308a355,360
> "Q80W99-1","29371110","Intramembranal disulfide cross-linking elucidates the super-quaternary structure of mammalian CatSpers.","Reproductive biology","2018 Mar","Bystroff C"
> "Q80W99-1","20586097","H2O2-induced up-regulation of CatSper3 in mouse brain.","Molecular reproduction and development","2010 Aug","Kim CW, Tak HM, Kim GT, Mun YJ, Jeon BT, Kim HJ, Roh GS, Han J, Kang D"
> "Q80W99-1","18607386","CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model.","Spinal cord","2009 Jan","Rezaian J, Movahedin M, Mowla SJ"
> "Q80W99-1","17344468","Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.","Biology of reproduction","2007 Jul","Jin J, Jin N, Zheng H, Ro S, Tafolla D, Sanders KM, Yan W"
> "Q80W99-1","16107607","Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.","Biology of reproduction","2005 Dec","Jin JL, O'Doherty AM, Wang S, Zheng H, Sanders KM, Yan W"
> "Q80W99-1","12932298","Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis.","Reproductive biology and endocrinology : RB&amp;E","2003 Aug 1","Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D"
309a362,363
> "P58659-1","25122090","EVA-1 functions as an UNC-40 Co-receptor to enhance attraction to the MADD-4 guidance cue in Caenorhabditis elegans.","PLoS genetics","2014 Aug","Chan KK, Seetharaman A, Bagg R, Selman G, Zhang Y, Kim J, Roy PJ"
> "P58659-1","24040182","The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system.","PloS one","2013","James G, Foster SR, Key B, Beverdam A"
320,322d373
< "Q08874-1","30471646","Distribution of mast cells within the mouse heart and its dependency on Mitf.","Molecular immunology","2019 Jan","Ingason AB, Mechmet F, Atacho DAM, Steingrimsson E, Petersen PH"
< "Q08874-1","17438132","Microphthalmia transcription factor isoforms in mast cells and the heart.","Molecular and cellular biology","2007 Jun","Tshori S, Sonnenblick A, Yannay-Cohen N, Kay G, Nechushtan H, Razin E"
< "Q08874-1","17182576","Distinct and shared transcriptomes are regulated by microphthalmia-associated transcription factor isoforms in mast cells.","Journal of immunology (Baltimore, Md. : 1950)","2007 Jan 1","Shahlaee AH, Brandal S, Lee YN, Jie C, Takemoto CM"
325a377,382
> "P52479-1","30898698","Long noncoding RNA Mirt2 upregulates USP10 expression to suppress hepatic steatosis by sponging miR-34a-5p.","Gene","2019 Jun 5","Zhang B, Li H, Li D, Sun H, Li M, Hu H"
> "P52479-1","29698567","Ubiquitin-Specific Peptidase 10 (USP10) Inhibits Hepatic Steatosis, Insulin Resistance, and Inflammation Through Sirt6.","Hepatology (Baltimore, Md.)","2018 Nov","Luo P, Qin C, Zhu L, Fang C, Zhang Y, Zhang H, Pei F, Tian S, Zhu XY, Gong J, Mao Q, Xiao C, Su Y, Zheng H, Xu T, Lu J, Zhang J"
> "P52479-1","28852924","USP10 inhibits lung cancer cell growth and invasion by upregulating PTEN.","Molecular and cellular biochemistry","2018 Apr","Sun J, Li T, Zhao Y, Huang L, Sun H, Wu H, Jiang X"
> "P52479-1","27974222","USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells.","Stem cell reports","2016 Dec 13","Higuchi M, Kawamura H, Matsuki H, Hara T, Takahashi M, Saito S, Saito K, Jiang S, Naito M, Kiyonari H, Fujii M"
> "P52479-1","26393420","A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation.","eLife","2015 Sep 22","Li L, Martinez SS, Hu W, Liu Z, Tjian R"
> "P52479-1","18632802","Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3.","American journal of physiology. Renal physiology","2008 Oct","Boulkroun S, Ruffieux-Daidie D, Vitagliano JJ, Poirot O, Charles RP, Lagnaz D, Firsov D, Kellenberger S, Staub O"
327c384,385
< "Q32MG2-1","12204287","Nurit, a novel leucine-zipper protein, expressed uniquely in the spermatid flower-like structure.","Mechanisms of development","2002 Sep","Feige E, Chen A, Motro B"
---
> "Q8C5L3-1","24200330","Identification of Ccr4-not complex components as regulators of transition from partial to genuine induced pluripotent stem cells.","Stem cells and development","2014 Sep 15","Kamon M, Katano M, Hiraki-Kamon K, Hishida T, Nakachi Y, Mizuno Y, Okazaki Y, Suzuki A, Hirasaki M, Ueda A, Nishimoto M, Kato H, Okuda A"
> "Q8C5L3-1","22367759","Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation.","Stem cells (Dayton, Ohio)","2012 May","Zheng X, Dumitru R, Lackford BL, Freudenberg JM, Singh AP, Archer TK, Jothi R, Hu G"
330,331d387
< "P59055-1","23076708","Differential promoter methylation and histone modification contribute to the brain specific expression of the mouse Mbu-1 gene.","Molecules and cells","2012 Nov","Kim B, Kang S, Kim SJ"
< "P59055-1","17433858","Characterization of a novel mouse brain gene (mbu-1) identified by digital differential display.","Gene","2007 Jun 15","Yang HL, Cho EY, Han KH, Kim H, Kim SJ"
334a391,394
> "Q8BYH8-1","29665362","Chd9 mediates highly loosened chromatin structure in growing mouse oocytes.","Biochemical and biophysical research communications","2018 Jun 7","Ooga M, Funaya S, Hashioka Y, Fujii W, Naito K, Suzuki MG, Aoki F"
> "Q8BYH8-1","25689118","New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes.","Journal of cellular physiology","2015 Sep","Salomon-Kent R, Marom R, John S, Dundr M, Schiltz LR, Gutierrez J, Workman J, Benayahu D, Hager GL"
> "Q8BYH8-1","16523501","Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors.","Journal of cellular physiology","2006 Jun","Marom R, Shur I, Hager GL, Benayahu D"
> "Q8BYH8-1","16419031","In vivo association of CReMM/CHD9 with promoters in osteogenic cells.","Journal of cellular physiology","2006 May","Shur I, Socher R, Benayahu D"
340a401,403
> "Q07235-1","28706437","Comparison of two neurotrophic serpins reveals a small fragment with cell survival activity.","Molecular vision","2017","Winokur PN, Subramanian P, Bullock JL, Arocas V, Becerra SP"
> "Q8K2P6-1","21238580","Primary role of mitochondrial Rieske iron-sulfur protein in hypoxic ROS production in pulmonary artery myocytes.","Free radical biology &amp; medicine","2011 Apr 15","Korde AS, Yadav VR, Zheng YM, Wang YX"
> "Q8K2P6-1","18703841","X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus.","Acta crystallographica. Section D, Biological crystallography","2008 Sep","Levin EJ, Elsen NL, Seder KD, McCoy JG, Fox BG, Phillips GN Jr"
342d404
< "Q8BYW1-1","27566826","Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice.","Journal of immunology (Baltimore, Md. : 1950)","2016 Oct 1","Csepanyi-Komi R, Wisniewski E, Bartos B, Levai P, Nemeth T, Balazs B, Kurz AR, Bierschenk S, Sperandio M, Ligeti E"
351a414
> "Q80TL4-1","27145804","Peripheral nerve injury induces loss of nociceptive neuron-specific Galphai-interacting protein in neuropathic pain rat.","Molecular pain","2016","Liu Z, Wang F, Fischer G, Hogan QH, Yu H"
358d420
< "P97931-1","28775312","Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.","Scientific reports","2017 Aug 3","Alsoe L, Sarno A, Carracedo S, Domanska D, Dingler F, Lirussi L, SenGupta T, Tekin NB, Jobert L, Alexandrov LB, Galashevskaya A, Rada C, Sandve GK, Rognes T, Krokan HE, Nilsen H"
373,376c435,437
< "Q64702-1","28972102","Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes.","The Journal of cell biology","2017 Nov 6","Bury L, Coelho PA, Simeone A, Ferries S, Eyers CE, Eyers PA, Zernicka-Goetz M, Glover DM"
< "Q64702-1","26595384","Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis.","Nature cell biology","2016 Jan","Sercin O, Larsimont JC, Karambelas AE, Marthiens V, Moers V, Boeckx B, Le Mercier M, Lambrechts D, Basto R, Blanpain C"
< "Q64702-1","26439168","Loss of KLF14 triggers centrosome amplification and tumorigenesis.","Nature communications","2015 Oct 6","Fan G, Sun L, Shan P, Zhang X, Huan J, Zhang X, Li D, Wang T, Wei T, Zhang X, Gu X, Yao L, Xuan Y, Hou Z, Cui Y, Cao L, Li X, Zhang S, Wang C"
< "Q64702-1","12352953","The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization.","Nature structural biology","2002 Oct","Leung GC, Hudson JW, Kozarova A, Davidson A, Dennis JW, Sicheri F"
---
> "Q2TV84-1","29854741","Different Activity Patterns in Retinal Ganglion Cells of TRPM1 and mGluR6 Knockout Mice.","BioMed research international","2018","Takeuchi H, Horie S, Moritoh S, Matsushima H, Hori T, Kimori Y, Kitano K, Tsubo Y, Tachibana M, Koike C"
> "Q2TV84-1","28899920","The TRPM1 Channel Is Required for Development of the Rod ON Bipolar Cell-AII Amacrine Cell Pathway in the Retinal Circuit.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Oct 11","Kozuka T, Chaya T, Tamalu F, Shimada M, Fujimaki-Aoba K, Kuwahara R, Watanabe SI, Furukawa T"
> "Q2TV84-1","19966281","TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.","Proceedings of the National Academy of Sciences of the United States of America","2010 Jan 5","Koike C, Obara T, Uriu Y, Numata T, Sanuki R, Miyata K, Koyasu T, Ueno S, Funabiki K, Tani A, Ueda H, Kondo M, Mori Y, Tachibana M, Furukawa T"
381a443,446
> "Q9D032-1","27236334","Single-stranded DNA binding protein Ssbp3 induces differentiation of mouse embryonic stem cells into trophoblast-like cells.","Stem cell research &amp; therapy","2016 May 28","Liu J, Luo X, Xu Y, Gu J, Tang F, Jin Y, Li H"
> "Q9D032-1","26495868","SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic beta-Cell Target Genes.","Molecular endocrinology (Baltimore, Md.)","2015 Dec","Galloway JR, Bethea M, Liu Y, Underwood R, Mobley JA, Hunter CS"
> "Q9D032-1","15857913","Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.","Development (Cambridge, England)","2005 Jun","Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H"
> "Q91VA3-1","16476741","Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.","The Journal of biological chemistry","2006 Apr 21","Hata S, Koyama S, Kawahara H, Doi N, Maeda T, Toyama-Sorimachi N, Abe K, Suzuki K, Sorimachi H"
382a448,450
> "Q8BWF2-1","29382851","Gimap5-dependent inactivation of GSK3beta is required for CD4(+) T cell homeostasis and prevention of immune pathology.","Nature communications","2018 Jan 30","Patterson AR, Endale M, Lampe K, Aksoylar HI, Flagg A, Woodgett JR, Hildeman D, Jordan MB, Singh H, Kucuk Z, Bleesing J, Hoebe K"
> "Q8BWF2-1","27023180","TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5).","PloS one","2016","Chen XL, Serrano D, Ghobadi F, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S"
> "Q8BWF2-1","25944983","Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut.","Mediators of inflammation","2015","Endale M, Aksoylar HI, Hoebe K"
389a458,460
> "Q7TQ33-1","27545491","Effects of maternal lead exposure on RGMa and RGMb expression in the hippocampus and cerebral cortex of mouse pups.","Brain research bulletin","2016 Oct","Li N, Qiao M, Zhao Q, Zhang P, Song L, Li L, Cui C"
> "Q7TQ33-1","14985445","DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2004 Feb 25","Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, Ji RR, Fabrizio DA, Zhang Y, Lin HY, Bell E, Woolf CJ"
> "Q7TQ33-1","14678836","Isolation and expression pattern of three mouse homologues of chick Rgm.","Gene expression patterns : GEP","2004 Jan","Schmidtmer J, Engelkamp D"
391a463
> "Q99LI5-1","29941555","ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma.","Proceedings of the National Academy of Sciences of the United States of America","2018 Jul 10","Pieraccioli M, Nicolai S, Pitolli C, Agostini M, Antonov A, Malewicz M, Knight RA, Raschella G, Melino G"
394a467
> "Q8C726-1","18363860","Of mice and men, periodic limb movements and iron: how the human genome informs the mouse genome.","Genes, brain, and behavior","2008 Jul","Jones LC, Earley CJ, Allen RP, Jones BC"
400,404c473,475
< "Q9ERD6-1","17462626","Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase.","Experimental cell research","2007 Jul 1","Ceriani M, Scandiuzzi C, Amigoni L, Tisi R, Berruti G, Martegani E"
< "Q5UAK0-3","26938916","Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.","PLoS genetics","2016 Mar","Lakisic G, Lebreton A, Pourpre R, Wendling O, Libertini E, Radford EJ, Le Guillou M, Champy MF, Wattenhofer-Donze M, Soubigou G, Ait-Si-Ali S, Feunteun J, Sorg T, Coppee JY, Ferguson-Smith AC, Cossart P, Bierne H"
< "Q5UAK0-3","17622490","Protein expression of the transcriptional regulator MI-ER1 alpha in adult mouse tissues.","Journal of molecular histology","2008 Feb","Thorne LB, McCarthy PL, Paterno GD, Gillespie LL"
< "Q5UAK0-3","16147882","Cloning and characterization of the mouse ortholog of mi-er1.","DNA sequence : the journal of DNA sequencing and mapping","2005 Jun","Thorne LB, Grant AL, Paterno GD, Gillespie LL"
< "Q6RFH4-1","15482850","Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells.","Molecular immunology","2004 Nov","Steinke JW, Hodsdon W, Parenti S, Ostraat R, Lutz R, Borish L, Hagman J"
---
> "Q61990-1","29422543","Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA.","Experimental &amp; molecular medicine","2018 Feb 9","Kim JK, Kim I, Choi K, Choi JH, Kim E, Lee HY, Park J, Kim Yoon S"
> "Q61990-1","27215387","Poly(rC)-Binding Protein 2 Regulates Hippo Signaling To Control Growth in Breast Epithelial Cells.","Molecular and cellular biology","2016 Aug 15","Li F, Bullough KZ, Vashisht AA, Wohlschlegel JA, Philpott CC"
> "Q61990-1","26907686","RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant Defense.","The Journal of biological chemistry","2016 Apr 29","Ren C, Zhang J, Yan W, Zhang Y, Chen X"
412c483
< "Q8CC21-1","28673544","TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.","Molecular cell","2017 Jul 6","Bottani E, Cerutti R, Harbour ME, Ravaglia S, Dogan SA, Giordano C, Fearnley IM, D'Amati G, Viscomi C, Fernandez-Vizarra E, Zeviani M"
---
> "Q8BK26-1","25970626","FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex.","PloS one","2015","Sjogren B, Swaney S, Neubig RR"
415a487,495
> "Q8CJH3-1","12196628","The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.","Proceedings of the National Academy of Sciences of the United States of America","2002 Sep 17","Aurandt J, Vikis HG, Gutkind JS, Ahn N, Guan KL"
> "Q8CJH3-1","12198496","The semaphorin 4D receptor controls invasive growth by coupling with Met.","Nature cell biology","2002 Sep","Giordano S, Corso S, Conrotto P, Artigiani S, Gilestro G, Barberis D, Tamagnone L, Comoglio PM"
> "Q80U62-1","30783089","Suppression of autophagic activity by Rubicon is a signature of aging.","Nature communications","2019 Feb 19","Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T"
> "Q80U62-1","19270696","Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.","Nature cell biology","2009 Apr","Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T, Akira S, Noda T, Yoshimori T"
> "Q80U62-1","19270693","Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.","Nature cell biology","2009 Apr","Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z"
> "Q8CGM1-1","28894906","Whole exome sequencing reveals a functional mutation in the GAIN domain of the Bai2 receptor underlying a forward mutagenesis hyperactivity QTL.","Mammalian genome : official journal of the International Mammalian Genome Society","2017 Dec","Speca DJ, Trimmer JS, Peterson AS, Diaz E"
> "Q8CGM1-1","20367554","Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing.","Journal of receptor and signal transduction research","2010 Jun","Okajima D, Kudo G, Yokota H"
> "Q8CGM1-1","16412436","Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor.","FEBS letters","2006 Jan 23","Jeong BC, Kim MY, Lee JH, Kee HJ, Kho DH, Han KE, Qian YR, Kim JK, Kim KK"
> "Q920B0-1","29947801","An FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency.","Human molecular genetics","2018 Oct 1","Kong Y, Zhao L, Charette JR, Hicks WL, Stone L, Nishina PM, Naggert JK"
417a498
> "P24161-1","28733484","Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 1","Bettini ML, Chou PC, Guy CS, Lee T, Vignali KM, Vignali DAA"
419,422d499
< "Q9R0L1-1","27586257","Heat shock factor 4 regulates lens epithelial cell homeostasis by working with lysosome and anti-apoptosis pathways.","The international journal of biochemistry &amp; cell biology","2016 Oct","Cui X, Liu H, Li J, Guo K, Han W, Dong Y, Wan S, Wang X, Jia P, Li S, Ma Y, Zhang J, Mu H, Hu Y"
< "Q9R0L1-1","15483628","HSF4 is required for normal cell growth and differentiation during mouse lens development.","The EMBO journal","2004 Oct 27","Fujimoto M, Izu H, Seki K, Fukuda K, Nishida T, Yamada S, Kato K, Yonemura S, Inouye S, Nakai A"
< "O88509-1","30468428","Targets and genomic constraints of ectopic Dnmt3b expression.","eLife","2018 Nov 23","Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A"
< "O88509-1","21666347","The Dnmt3b splice variant is specifically expressed in in vitro-manipulated blastocysts and their derivative ES cells.","The Journal of reproduction and development","2011 Oct","Horii T, Suetake I, Yanagisawa E, Morita S, Kimura M, Nagao Y, Imai H, Tajima S, Hatada I"
425a503
> "P58771-1","30567734","Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy.","The Journal of biological chemistry","2019 Feb 22","Rajan S, Jagatheesan G, Petrashevskaya N, Biesiadecki BJ, Warren CM, Riddle T, Liggett S, Wolska BM, Solaro RJ, Wieczorek DF"
427c505
< "Q9JMD0-1","27177335","Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes.","Oncotarget","2016 May 24","Dai XX, Xiong H, Zhang M, Sun S, Xiong B"
---
> "Q8C255-1","12738806","Identification of two additional members of the membrane-bound dipeptidase family.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2003 Jul","Habib GM, Shi ZZ, Cuevas AA, Lieberman MW"
429a508,512
> "Q3URD3-1","22180652","Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum.","American journal of physiology. Heart and circulatory physiology","2012 Mar 1","Nader M, Westendorp B, Hawari O, Salih M, Stewart AF, Leenen FH, Tuana BS"
> "Q3URD3-1","21785580","Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice.","Experimental diabetes research","2011","Chen X, Ding H"
> "Q3V0B4-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
> "Q8CAE2-1","29703750","Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain.","The Journal of biological chemistry","2018 Jun 29","Peng L, Zhang F, Shang R, Wang X, Chen J, Chou JJ, Ma J, Wu L, Huang Y"
> "Q8CAE2-1","26496356","HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.","PLoS genetics","2015 Oct","Lim SL, Qu ZP, Kortschak RD, Lawrence DM, Geoghegan J, Hempfling AL, Bergmann M, Goodnow CC, Ormandy CJ, Wong L, Mann J, Scott HS, Jamsai D, Adelson DL, O'Bryan MK"
445a529
> "P97459-1","28499489","Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes.","Biological psychiatry","2017 Aug 1","Michaelson JJ, Shin MK, Koh JY, Brueggeman L, Zhang A, Katzman A, McDaniel L, Fang M, Pufall M, Pieper AA"
447a532,537
> "Q3UUY6-1","20333396","Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney.","Histochemistry and cell biology","2010 May","Jaszai J, Farkas LM, Fargeas CA, Janich P, Haase M, Huttner WB, Corbeil D"
> "Q3UUY6-1","18536929","Robust expression of Prominin-2 all along the adult male reproductive system and urinary bladder.","Histochemistry and cell biology","2008 Oct","Jaszai J, Fargeas CA, Haase M, Farkas LM, Huttner WB, Corbeil D"
> "Q3UUY6-1","17874118","Differential expression of Prominin-1 (CD133) and Prominin-2 in major cephalic exocrine glands of adult mice.","Histochemistry and cell biology","2007 Nov","Jaszai J, Janich P, Farkas LM, Fargeas CA, Huttner WB, Corbeil D"
> "Q3UUY6-1","17109118","Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine.","Cell and tissue research","2007 Apr","Florek M, Bauer N, Janich P, Wilsch-Braeuninger M, Fargeas CA, Marzesco AM, Ehninger G, Thiele C, Huttner WB, Corbeil D"
> "Q3UUY6-1","12514187","Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins.","The Journal of biological chemistry","2003 Mar 7","Fargeas CA, Florek M, Huttner WB, Corbeil D"
> "Q9JJ43-1","30001398","Downregulation of splicing regulator RBFOX1 compromises visual depth perception.","PloS one","2018","Gu L, Bok D, Yu F, Caprioli J, Piri N"
454a545,546
> "Q8BLU0-1","28576770","Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.","Development (Cambridge, England)","2017 Jul 1","Tai-Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, Ieda M, Takakura N, Nakagawa O, Zhou B, Okabayashi K, Suematsu M, Kitagawa Y, Bastmeyer M, Sato K, Klein R, Navankasattusas S, Li DY, Yamagishi S, Kubota Y"
> "Q8BLU0-1","16872596","Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.","Developmental biology","2006 Sep 1","Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW"
456a549
> "Q6TCG8-1","17724343","Spatial regulation of Raf kinase signaling by RKTG.","Proceedings of the National Academy of Sciences of the United States of America","2007 Sep 4","Feng L, Xie X, Ding Q, Luo X, He J, Fan F, Liu W, Wang Z, Chen Y"
461a555,559
> "Q8K1E3-1","28863347","Deletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam.","Psychoneuroendocrinology","2017 Nov","Navarrete F, Garcia-Gutierrez MS, Laborda J, Manzanares J"
> "Q8K1E3-1","22306741","DLK2 is a transcriptional target of KLF4 in the early stages of adipogenesis.","Journal of molecular biology","2012 Mar 16","Rivero S, Diaz-Guerra MJ, Monsalve EM, Laborda J, Garcia-Ramirez JJ"
> "Q8K1E3-1","22185379","Characterization of a proximal Sp1 response element in the mouse Dlk2 gene promoter.","BMC molecular biology","2011 Dec 20","Rivero S, Ruiz-Garcia A, Diaz-Guerra MJ, Laborda J, Garcia-Ramirez JJ"
> "Q8K1E3-1","21419176","The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities.","Biochimica et biophysica acta","2011 Jun","Sanchez-Solana B, Nueda ML, Ruvira MD, Ruiz-Hidalgo MJ, Monsalve EM, Rivero S, Garcia-Ramirez JJ, Diaz-Guerra MJ, Baladron V, Laborda J"
> "Q8K1E3-1","17320102","The novel gene EGFL9/Dlk2, highly homologous to Dlk1, functions as a modulator of adipogenesis.","Journal of molecular biology","2007 Apr 13","Nueda ML, Baladron V, Garcia-Ramirez JJ, Sanchez-Solana B, Ruvira MD, Rivero S, Ballesteros MA, Monsalve EM, Diaz-Guerra MJ, Ruiz-Hidalgo MJ, Laborda J"
464a563,565
> "Q925J9-1","29293266","Med1 deficiency alters the somatic hypermutation spectrum in murine B cells.","European journal of immunology","2018 Apr","Gaudot L, Thomas-Claudepierre AS, Robert I, Schiavo E, Heyer V, Reina-San-Martin B"
> "Q925J9-1","29187405","HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1.","Cancer research","2018 Jan 15","Yang Y, Leonard M, Zhang Y, Zhao D, Mahmoud C, Khan S, Wang J, Lower EE, Zhang X"
> "Q925J9-1","28673966","Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene.","The Journal of biological chemistry","2017 Aug 18","Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, DenBesten PK, Bikle DD, Oda Y, Yamada Y"
470,472c571
< "Q9QZX7-1","29913163","Loss-of-function mutation of serine racemase attenuates retinal ganglion cell loss in diabetic mice.","Experimental eye research","2018 Oct","Jiang H, Du J, Song J, Li Y, Wu M, Zhou J, Wu S"
< "Q9QZX7-1","28892569","Serine racemase deficiency attenuates choroidal neovascularization and reduces nitric oxide and VEGF levels by retinal pigment epithelial cells.","Journal of neurochemistry","2017 Nov","Jiang H, Wu M, Liu Y, Song L, Li S, Wang X, Zhang YF, Fang J, Wu S"
< "Q9QZX7-1","12021263","Direct calcium binding results in activation of brain serine racemase.","The Journal of biological chemistry","2002 Aug 2","Cook SP, Galve-Roperh I, Martinez del Pozo A, Rodriguez-Crespo I"
---
> "Q8WTY4-1","16957168","Subcellular localization of CIAPIN1.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2006 Dec","Hao Z, Li X, Qiao T, Du R, Zhang G, Fan D"
477a577,578
> "Q8VDU5-1","28117339","Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling.","Nature communications","2017 Jan 24","Rines AK, Chang HC, Wu R, Sato T, Khechaduri A, Kouzu H, Shapiro J, Shang M, Burke MA, Abdelwahid E, Jiang X, Chen C, Rawlings TA, Lopaschuk GD, Schumacker PT, Abel ED, Ardehali H"
> "Q8VDU5-1","27780848","Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function.","Circulation. Cardiovascular genetics","2016 Dec","Cossette SM, Bhute VJ, Bao X, Harmann LM, Horswill MA, Sinha I, Gastonguay A, Pooya S, Bordas M, Kumar SN, Mirza SP, Palecek SP, Strande JL, Ramchandran R"
482,485c583
< "P97792-1","31083261","CEACAM-1 promotes myocardial injury following coxsackievirus infection by regulating the coxsackievirus-adenovirus receptor.","Medicine","2019 May","Zhang Z, Long C, Li X, Xie Q, Song M, Zhang Y"
< "P97792-1","28381574","Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum.","Journal of virology","2017 Jun 15","Lopez-Gordo E, Doszpoly A, Duffy MR, Coughlan L, Bradshaw AC, White KM, Denby L, Nicklin SA, Baker AH"
< "P97792-1","21674029","Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene.","PloS one","2011","Pazirandeh A, Sultana T, Mirza M, Rozell B, Hultenby K, Wallis K, Vennstrom B, Davis B, Arner A, Heuchel R, Lohr M, Philipson L, Sollerbrant K"
< "P97792-1","12823902","Structure and chromosomal localization of the murine coxsackievirus and adenovirus receptor gene.","DNA and cell biology","2003 Apr","Chen JW, Ghosh R, Finberg RW, Bergelson JM"
---
> "Q9D3D9-1","29499186","Role of the mitochondrial ATP synthase central stalk subunits gamma and delta in the activity and assembly of the mammalian enzyme.","Biochimica et biophysica acta. Bioenergetics","2018 May","Pecina P, Nuskova H, Karbanova V, Kaplanova V, Mracek T, Houstek J"
488a587,594
> "Q3TTY0-1","23943622","Phospholipase B is activated in response to sterol removal and stimulates acrosome exocytosis in murine sperm.","The Journal of biological chemistry","2013 Sep 27","Asano A, Nelson-Harrington JL, Travis AJ"
> "Q99J78-1","10460589","Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system.","British journal of haematology","1999 Aug","Hotfilder M, Baxendale S, Cross MA, Sablitzky F"
> "Q8BPM0-1","28682694","Daam1 regulates fascin for actin assembly in mouse oocyte meiosis.","Cell cycle (Georgetown, Tex.)","2017 Jul 18","Lu Y, Zhang Y, Pan MH, Kim NH, Sun SC, Cui XS"
> "Q8BPM0-1","27807130","DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.","The Journal of cell biology","2016 Nov 21","Nishimura T, Ito S, Saito H, Hiver S, Shigetomi K, Ikenouchi J, Takeichi M"
> "Q8BPM0-1","27760153","Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network.","PloS one","2016","Luo W, Lieu ZZ, Manser E, Bershadsky AD, Sheetz MP"
> "Q8BPM0-1","15533824","Identification and comparative expression analyses of Daam genes in mouse and Xenopus.","Gene expression patterns : GEP","2004 Nov","Nakaya MA, Habas R, Biris K, Dunty WC Jr, Kato Y, He X, Yamaguchi TP"
> "Q8BPM0-1","15464228","Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.","Brain research. Developmental brain research","2004 Oct 15","Kida Y, Shiraishi T, Ogura T"
> "Q91VW9-1","18940803","Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets.","The Journal of biological chemistry","2008 Dec 12","Yang L, Zhang L, Wu Q, Boyd DD"
490a597,599
> "Q6GQT0-1","29293958","CDC14A phosphatase is essential for hearing and male fertility in mouse and human.","Human molecular genetics","2018 Mar 1","Imtiaz A, Belyantseva IA, Beirl AJ, Fenollar-Ferrer C, Bashir R, Bukhari I, Bouzid A, Shaukat U, Azaiez H, Booth KT, Kahrizi K, Najmabadi H, Maqsood A, Wilson EA, Fitzgerald TS, Tlili A, Olszewski R, Lund M, Chaudhry T, Rehman AU, Starost MF, Waryah AM, Hoa M, Dong L, Morell RJ, Smith RJH, Riazuddin S, Masmoudi S, Kindt KS, Naz S, Friedman TB"
> "Q6GQT0-1","26283732","Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.","Molecular and cellular biology","2015 Nov","Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, Zhang P"
> "Q6GQT0-1","19270517","The CDC14A phosphatase regulates oocyte maturation in mouse.","Cell cycle (Georgetown, Tex.)","2009 Apr 1","Schindler K, Schultz RM"
499,506d607
< "P59438-1","27333462","Simple chronic colitis model using hypopigmented mice with a Hermansky-Pudlak syndrome 5 gene mutation.","Pigment cell &amp; melanoma research","2016 Sep","Itoh Y, Nagaoka Y, Katakura Y, Kawahara H, Takemori H"
< "P59438-1","23672590","The mouse ruby-eye 2(d) (ru2(d) /Hps5(ru2-d) ) allele inhibits eumelanin but not pheomelanin synthesis.","Pigment cell &amp; melanoma research","2013 Sep","Hirobe T, Ito S, Wakamatsu K"
< "P59438-1","23030338","A new mutation of mouse ruby-eye 2, ru2(d)/Hps5(ru2-d) inhibits eumelanin synthesis but stimulates pheomelanin synthesis in melanocytes.","Zoological science","2012 Oct","Hirobe T, Wakamatsu K, Ito S"
< "P59438-1","22035301","A novel deletion mutation of mouse ruby-eye 2 named ru2(d)/Hps5(ru2-d) inhibits melanocyte differentiation and its impaired differentiation is rescued by L-tyrosine.","Zoological science","2011 Nov","Hirobe T, Yoshihara C, Takeuchi S, Wakamatsu K, Ito S, Abe H, Kawa Y, Soma Y"
< "Q6PHZ8-1","23457522","Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.","PloS one","2013","Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST"
< "Q6PHZ8-1","20550899","Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.","Biophysical journal","2010 Jun 16","Liang P, Chen H, Cui Y, Lei L, Wang K"
< "Q6PHZ8-1","20045463","KChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation.","Molecular and cellular neurosciences","2010 Mar","Lin L, Sun W, Wikenheiser AM, Kung F, Hoffman DA"
< "Q6PHZ8-1","15363885","Differential distribution of KChIPs mRNAs in adult mouse brain.","Brain research. Molecular brain research","2004 Sep 28","Xiong H, Kovacs I, Zhang Z"
511d611
< "Q05BC3-1","24859200","Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.","Nature neuroscience","2014 Jul","Kielar M, Tuy FP, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, Oegema R, Mancini GM, Bahi-Buisson N, Olaso R, Le Moing AG, Boutourlinsky K, Boucher D, Carpentier W, Berquin P, Deleuze JF, Belvindrah R, Borrell V, Welker E, Chelly J, Croquelois A, Francis F"
513,514d612
< "Q8BJ52-1","25074937","Plasticity-related gene 5 promotes spine formation in murine hippocampal neurons.","The Journal of biological chemistry","2014 Sep 5","Coiro P, Stoenica L, Strauss U, Brauer AU"
< "Q8BJ52-1","20032306","Plasticity-related gene 5 (PRG5) induces filopodia and neurite growth and impedes lysophosphatidic acid- and nogo-A-mediated axonal retraction.","Molecular biology of the cell","2010 Feb 15","Broggini T, Nitsch R, Savaskan NE"
521c619
< "P97477-1","29842884","Novel localization of Aurora A kinase in mouse testis suggests multiple roles in spermatogenesis.","Biochemical and biophysical research communications","2018 Sep 3","Johnson ML, Wang R, Sperry AO"
---
> "Q9JLC6-1","30515906","Thyrotroph embryonic factor is downregulated in bladder cancer and suppresses proliferation and tumorigenesis via the AKT/FOXOs signalling pathway.","Cell proliferation","2019 Mar","Yang J, Wang B, Chen H, Chen X, Li J, Chen Y, Yuan D, Zheng S"
522a621,623
> "Q9R1X4-1","25448545","Morphological characterization of mammalian timeless in the mouse brain development.","Neuroscience research","2015 Mar","Inaguma Y, Ito H, Hara A, Iwamoto I, Matsumoto A, Yamagata T, Tabata H, Nagata K"
> "Q9R1X4-1","23266470","Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.","Cellular signalling","2013 Apr","O'Reilly LP, Zhang X, Smithgall TE"
> "Q9R1X4-1","23418588","Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.","PloS one","2013","Engelen E, Janssens RC, Yagita K, Smits VA, van der Horst GT, Tamanini F"
525a627,630
> "Q8BH75-1","26390156","K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.","Nature immunology","2015 Dec","Yang M, Chen T, Li X, Yu Z, Tang S, Wang C, Gu Y, Liu Y, Xu S, Li W, Zhang X, Wang J, Cao X"
> "Q8BH75-1","26085571","Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in beta-Cells.","Diabetes","2015 Oct","Soleimanpour SA, Ferrari AM, Raum JC, Groff DN, Yang J, Kaufman BA, Stoffers DA"
> "Q8BH75-1","22707723","The E3 ubiquitin ligase neuregulin receptor degradation protein 1 (Nrdp1) promotes M2 macrophage polarization by ubiquitinating and activating transcription factor CCAAT/enhancer-binding Protein beta (C/EBPbeta).","The Journal of biological chemistry","2012 Aug 3","Ye S, Xu H, Jin J, Yang M, Wang C, Yu Y, Cao X"
> "Q8BH75-1","21738612","Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in mice.","PloS one","2011","Zhang Y, Kang YM, Tian C, Zeng Y, Jia LX, Ma X, Du J, Li HH"
528a634,638
> "Q9D411-1","26940607","Phosphorylated testis-specific serine/threonine kinase 4 may phosphorylate Crem at Ser-117.","Bioscience, biotechnology, and biochemistry","2016 Jun","Fu G, Wei Y, Wang X, Yu L"
> "Q9D411-1","26961893","Testis-specific serine/threonine protein kinase 4 (Tssk4) phosphorylates Odf2 at Ser-76.","Scientific reports","2016 Mar 10","Wang X, Li H, Fu G, Wang Y, Du S, Yu L, Wei Y, Chen S"
> "Q9D411-1","25361759","Tssk4 is essential for maintaining the structural integrity of sperm flagellum.","Molecular human reproduction","2015 Feb","Wang X, Wei Y, Fu G, Li H, Saiyin H, Lin G, Wang Z, Chen S, Yu L"
> "Q9D411-1","23599433","Heat shock protein 90 functions to stabilize and activate the testis-specific serine/threonine kinases, a family of kinases essential for male fertility.","The Journal of biological chemistry","2013 Jun 7","Jha KN, Coleman AR, Wong L, Salicioni AM, Howcroft E, Johnson GR"
> "Q9D411-1","23054012","Testis specific serine/threonine kinase 4 (Tssk4) maintains its kinase activity by phosphorylating itself at Thr-197.","Molecular biology reports","2013 Jan","Wei Y, Wang X, Fu G, Yu L"
534,535d643
< "Q8BK06-1","27197753","F-box only protein 9 is an E3 ubiquitin ligase of PPARgamma.","Experimental &amp; molecular medicine","2016 May 20","Lee KW, Kwak SH, Koo YD, Cho YK, Lee HM, Jung HS, Cho YM, Park YJ, Chung SS, Park KS"
< "Q8BK06-1","20459822","The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors.","Molecular cancer","2010 May 11","Sturgill TW, Stoddard PB, Cohn SM, Mayo MW"
536a645,647
> "G5E8K5-1","30562487","Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.","Developmental biology","2019 Feb 1","Rasiah PK, Maddala R, Bennett V, Rao PV"
> "G5E8K5-1","30046097","Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling.","Translational psychiatry","2018 Jul 25","Garza JC, Qi X, Gjeluci K, Leussis MP, Basu H, Reis SA, Zhao WN, Piguel NH, Penzes P, Haggarty SJ, Martens GJ, Poelmans G, Petryshen TL"
> "G5E8K5-1","29963618","Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan.","eNeuro","2018 May-Jun","Taylor AM, Shi Q, Bhat MA"
538,539d648
< "Q8CHH9-1","27084579","SEPT8 modulates beta-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.","Journal of cell science","2016 Jun 1","Kurkinen KM, Marttinen M, Turner L, Natunen T, Makinen P, Haapalinna F, Sarajarvi T, Gabbouj S, Kurki M, Paananen J, Koivisto AM, Rauramaa T, Leinonen V, Tanila H, Soininen H, Lucas FR, Haapasalo A, Hiltunen M"
< "Q8CHH9-1","21770032","Proteins linked to extinction in contextual fear conditioning in the C57BL/6J mouse.","Proteomics","2011 Sep","Li L, Boddul SV, Patil SS, Zheng JF, An G, Hoger H, Lubec G"
542,549c651
< "P97443-1","30061404","Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.","Proceedings of the National Academy of Sciences of the United States of America","2018 Aug 14","Warren JS, Tracy CM, Miller MR, Makaju A, Szulik MW, Oka SI, Yuzyuk TN, Cox JE, Kumar A, Lozier BK, Wang L, Llana JG, Sabry AD, Cawley KM, Barton DW, Han YH, Boudina S, Fiehn O, Tucker HO, Zaitsev AV, Franklin S"
< "P97443-1","29499397","siRNA-mediated inhibition of skNAC and Smyd1 expression disrupts myofibril organization: Immunofluorescence and electron microscopy study in C2C12 cells.","Micron (Oxford, England : 1993)","2018 May","Berkholz J, Eberle R, Boller K, Munz B"
< "P97443-1","27663768","The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.","American journal of physiology. Heart and circulatory physiology","2016 Nov 1","Franklin S, Kimball T, Rasmussen TL, Rosa-Garrido M, Chen H, Tran T, Miller MR, Gray R, Jiang S, Ren S, Wang Y, Tucker HO, Vondriska TM"
< "P97443-1","26935107","Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray.","Disease models &amp; mechanisms","2016 Mar","Stewart MD, Lopez S, Nagandla H, Soibam B, Benham A, Nguyen J, Valenzuela N, Wu HJ, Burns AR, Rasmussen TL, Tucker HO, Schwartz RJ"
< "P97443-1","12011100","m-Bop, a repressor protein essential for cardiogenesis, interacts with skNAC, a heart- and muscle-specific transcription factor.","The Journal of biological chemistry","2002 Jul 19","Sims RJ 3rd, Weihe EK, Zhu L, O'Malley S, Harriss JV, Gottlieb PD"
< "P97443-1","11923873","Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.","Nature genetics","2002 May","Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D"
< "Q8VDQ1-1","17449869","Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation.","The Journal of biological chemistry","2007 Jun 22","Chou WL, Chuang LM, Chou CC, Wang AH, Lawson JA, FitzGerald GA, Chang ZF"
< "Q8VDQ1-1","15229897","Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution.","Proteins","2004 Aug 15","Levin I, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hampton E, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Reyes R, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA"
---
> "Q571I4-1","15289607","The mouse kinome: discovery and comparative genomics of all mouse protein kinases.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G"
560,561c662,666
< "Q8CG19-1","27956181","Latent TGF-beta binding protein-1 deficiency decreases female fertility.","Biochemical and biophysical research communications","2017 Jan 22","Dietzel E, Weiskirchen S, Floehr J, Horiguchi M, Todorovic V, Rifkin DB, Jahnen-Dechent W, Weiskirchen R"
< "Q8CG19-1","25805620","Abrogation of both short and long forms of latent transforming growth factor-beta binding protein-1 causes defective cardiovascular development and is perinatally lethal.","Matrix biology : journal of the International Society for Matrix Biology","2015 Apr","Horiguchi M, Todorovic V, Hadjiolova K, Weiskirchen R, Rifkin DB"
---
> "Q9WTP6-1","24740601","Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm.","Biology of reproduction","2014 Jun","Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL"
> "Q9WTP6-1","24548998","The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth.","Nature communications","2014","Kim H, Lee HJ, Oh Y, Choi SG, Hong SH, Kim HJ, Lee SY, Choi JW, Su Hwang D, Kim KS, Kim HJ, Zhang J, Youn HJ, Noh DY, Jung YK"
> "Q9WTP6-1","20876536","Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response.","The Journal of biological chemistry","2011 Feb 11","Burkart A, Shi X, Chouinard M, Corvera S"
> "Q9WTP6-1","20728450","Akt2 deficiency promotes cardiac induction of Rab4a and myocardial beta-adrenergic hypersensitivity.","Journal of molecular and cellular cardiology","2010 Dec","Etzion S, Etzion Y, DeBosch B, Crawford PA, Muslin AJ"
> "Q3TQR0-1","15983387","Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.","Proceedings of the National Academy of Sciences of the United States of America","2005 Jul 5","Ishii H, Inageta T, Mimori K, Saito T, Sasaki H, Isobe M, Mori M, Croce CM, Huebner K, Ozawa K, Furukawa Y"
565c670
< "Q8R3L2-1","12107429","Nulp1, a novel basic helix-loop-helix protein expressed broadly during early embryonic organogenesis and prominently in developing dorsal root ganglia.","Cell and tissue research","2002 Jun","Olsson M, Durbeej M, Ekblom P, Hjalt T"
---
> "Q62225-1","28038963","Phosphorylated CIS suppresses the Epo or JAK2 V617F mutant-triggered cell proliferation through binding to EpoR.","Cellular signalling","2017 Feb","Funakoshi-Tago M, Moriwaki T, Ueda F, Tamura H, Kasahara T, Tago K"
569a675
> "Q7TMK6-1","19793914","Murine CENP-F regulates centrosomal microtubule nucleation and interacts with Hook2 at the centrosome.","Molecular biology of the cell","2009 Nov","Moynihan KL, Pooley R, Miller PM, Kaverina I, Bader DM"
576a683,684
> "Q8VEL0-1","21792907","Mospd1, a new player in mesenchymal versus epidermal cell differentiation.","Journal of cellular physiology","2011 Oct","Thaler R, Rumpler M, Spitzer S, Klaushofer K, Varga F"
> "Q9DBU5-1","16204183","The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.","Genes &amp; development","2005 Oct 1","Tursun B, Schluter A, Peters MA, Viehweger B, Ostendorff HP, Soosairajah J, Drung A, Bossenz M, Johnsen SA, Schweizer M, Bernard O, Bach I"
577a686,688
> "O08532-1","30355732","The alpha2delta-1-NMDA receptor coupling is essential for corticostriatal long-term potentiation and is involved in learning and memory.","The Journal of biological chemistry","2018 Dec 14","Zhou JJ, Li DP, Chen SR, Luo Y, Pan HL"
> "O08532-1","16460711","Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice.","Brain research","2006 Feb 23","Bian F, Li Z, Offord J, Davis MD, McCormick J, Taylor CP, Walker LC"
> "O08532-1","1847144","Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides.","The Journal of biological chemistry","1991 Feb 15","Jay SD, Sharp AH, Kahl SD, Vedvick TS, Harpold MM, Campbell KP"
582c693
< "Q8BHZ5-1","17043244","Isolation, characterization, and genetic complementation of a cellular mutant resistant to retroviral infection.","Proceedings of the National Academy of Sciences of the United States of America","2006 Oct 24","Agarwal S, Harada J, Schreifels J, Lech P, Nikolai B, Yamaguchi T, Chanda SK, Somia NV"
---
> "Q9QZ03-1","14525987","Structure, function, and regulation of a subfamily of mouse zinc transporter genes.","The Journal of biological chemistry","2003 Dec 12","Dufner-Beattie J, Langmade SJ, Wang F, Eide D, Andrews GK"
587,590d697
< "Q80XP9-1","26861815","Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke.","Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism","2017 Feb","Zhao H, Nepomuceno R, Gao X, Foley LM, Wang S, Begum G, Zhu W, Pigott VM, Falgoust LM, Kahle KT, Yang SS, Lin SH, Alper SL, Hitchens TK, Hu S, Zhang Z, Sun D"
< "Q80XP9-1","16357011","WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1).","The Journal of physiology","2006 Mar 1","Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC"
< "Q80XP9-1","16275913","WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.","Proceedings of the National Academy of Sciences of the United States of America","2005 Nov 15","Rinehart J, Kahle KT, de Los Heros P, Vazquez N, Meade P, Wilson FH, Hebert SC, Gimenez I, Gamba G, Lifton RP"
< "Q80XP9-1","16275911","WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.","Proceedings of the National Academy of Sciences of the United States of America","2005 Nov 15","Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP"
593,598d699
< "Q52KR2-1","26651291","Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.","Developmental cell","2015 Dec 7","van Erp S, van den Heuvel DMA, Fujita Y, Robinson RA, Hellemons AJCGM, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JAA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ"
< "Q52KR2-1","24023893","Lrig2-deficient mice are protected against PDGFB-induced glioma.","PloS one","2013","Rondahl V, Holmlund C, Karlsson T, Wang B, Faraz M, Henriksson R, Hedman H"
< "Q52KR2-1","24086156","In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.","PLoS genetics","2013","Del Rio T, Nishitani AM, Yu WM, Goodrich LV"
< "Q91X88-1","25085363","Role of glycosyltransferase PomGnT1 in glioblastoma progression.","Neuro-oncology","2015 Feb","Lan J, Guo P, Lin Y, Mao Q, Guo L, Ge J, Li X, Jiang J, Lin X, Qiu Y"
< "Q91X88-1","17034757","Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan.","Biochemical and biophysical research communications","2006 Dec 1","Xiong H, Kobayashi K, Tachikawa M, Manya H, Takeda S, Chiyonobu T, Fujikake N, Wang F, Nishimoto A, Morris GE, Nagai Y, Kanagawa M, Endo T, Toda T"
< "Q91X88-1","16458488","A genetic model for muscle-eye-brain disease in mice lacking protein O-mannose 1,2-N-acetylglucosaminyltransferase (POMGnT1).","Mechanisms of development","2006 Mar","Liu J, Ball SL, Yang Y, Mei P, Zhang L, Shi H, Kaminski HJ, Lemmon VP, Hu H"
611a713
> "Q30D77-1","12874293","Collagen XXIV, a vertebrate fibrillar collagen with structural features of invertebrate collagens: selective expression in developing cornea and bone.","The Journal of biological chemistry","2003 Oct 31","Koch M, Laub F, Zhou P, Hahn RA, Tanaka S, Burgeson RE, Gerecke DR, Ramirez F, Gordon MK"
613a716,718
> "Q9QWZ1-1","23468651","Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.","PLoS genetics","2013","Lyndaker AM, Lim PX, Mleczko JM, Diggins CE, Holloway JK, Holmes RJ, Kan R, Schlafer DH, Freire R, Cohen PE, Weiss RS"
> "Q9QWZ1-1","21637962","Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses.","Protein &amp; cell","2011 May","Zhang C, Liu Y, Hu Z, An L, He Y, Hang H"
> "Q9CS84-1","30262834","Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.","Nature communications","2018 Sep 27","Yamagata A, Goto-Ito S, Sato Y, Shiroshima T, Maeda A, Watanabe M, Saitoh T, Maenaka K, Terada T, Yoshida T, Uemura T, Fukai S"
615,624d719
< "P0C605-1","30327468","A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis.","Nature communications","2018 Oct 16","Wen L, Feil S, Wolters M, Thunemann M, Regler F, Schmidt K, Friebe A, Olbrich M, Langer H, Gawaz M, de Wit C, Feil R"
< "P0C605-1","30152261","Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion.","Molecular pain","2018 Jan-Dec","Uchida H, Matsumura S, Katano T, Watanabe M, Schlossmann J, Ito S"
< "Q5SSZ7-1","30692207","A ZNRF3-dependent Wnt/beta-catenin signaling gradient is required for adrenal homeostasis.","Genes &amp; development","2019 Feb 1","Basham KJ, Rodriguez S, Turcu AF, Lerario AM, Logan CY, Rysztak MR, Gomez-Sanchez CE, Breault DT, Koo BK, Clevers H, Nusse R, Val P, Hammer GD"
< "Q5SSZ7-1","29735715","ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.","Proceedings of the National Academy of Sciences of the United States of America","2018 May 22","Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes DT, Suzuki M, Burdine RD, Cong F, Koo BK, Clevers H, Stevant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A"
< "Q5SSZ7-1","24349440","Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.","PloS one","2013","Peng WC, de Lau W, Madoori PK, Forneris F, Granneman JC, Clevers H, Gros P"
< "Q5SSZ7-1","22575959","ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.","Nature","2012 Apr 29","Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F"
< "Q8C255-1","12738806","Identification of two additional members of the membrane-bound dipeptidase family.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2003 Jul","Habib GM, Shi ZZ, Cuevas AA, Lieberman MW"
< "Q9EPU0-1","29959727","Dysregulated Up-Frameshift Protein 1 Promotes Ulcerative Colitis Pathogenesis Through the TNFR1-NF-kappaB/MAPKs Pathway.","Digestive diseases and sciences","2018 Oct","Zhu H, Huang S, Yue M, Chen W, Lu C, Lou X, Li C, Shan G, Chen H, Xu X, Xu G, Chen L"
< "Q9EPU0-1","28128343","RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.","Scientific reports","2017 Jan 27","Mooney CM, Jimenez-Mateos EM, Engel T, Mooney C, Diviney M, Veno MT, Kjems J, Farrell MA, O'Brien DF, Delanty N, Henshall DC"
< "Q9EPU0-1","27149095","Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.","PLoS genetics","2016 May","Fanourgakis G, Lesche M, Akpinar M, Dahl A, Jessberger R"
625a721,723
> "Q9R0C8-1","30450647","The guanine nucleotide exchange factor Vav3 modulates oligodendrocyte precursor differentiation and supports remyelination in white matter lesions.","Glia","2019 Feb","Ulc A, Zeug A, Bauch J, van Leeuwen S, Kuhlmann T, Ffrench-Constant C, Ponimaskin E, Faissner A"
> "Q9R0C8-1","15365099","Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity.","The Journal of experimental medicine","2004 Sep 20","Cella M, Fujikawa K, Tassi I, Kim S, Latinis K, Nishi S, Yokoyama W, Colonna M, Swat W"
> "Q9R0C8-1","15249579","Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.","The Journal of cell biology","2004 Jul 19","Gakidis MA, Cullere X, Olson T, Wilsbacher JL, Zhang B, Moores SL, Ley K, Swat W, Mayadas T, Brugge JS"
628,631d725
< "A4QPC6-1","26809444","Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.","The Journal of experimental medicine","2016 Feb 8","Sarter K, Leimgruber E, Gobet F, Agrawal V, Dunand-Sauthier I, Barras E, Mastelic-Gavillet B, Kamath A, Fontannaz P, Guery L, Duraes Fdo V, Lippens C, Ravn U, Santiago-Raber ML, Magistrelli G, Fischer N, Siegrist CA, Hugues S, Reith W"
< "A4QPC6-1","20208008","BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.","Journal of immunology (Baltimore, Md. : 1950)","2010 Apr 1","Smith IA, Knezevic BR, Ammann JU, Rhodes DA, Aw D, Palmer DB, Mather IH, Trowsdale J"
< "Q9CZ30-1","27481995","OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression.","Molecular and cellular biology","2016 Oct 15","Ding Z, Liu Y, Rubio V, He J, Minze LJ, Shi ZZ"
< "Q9CZ30-1","26984302","Metal mixture (As-Cd-Pb)-induced cell transformation is modulated by OLA1.","Mutagenesis","2016 Jul","Martinez-Baeza E, Rojas E, Valverde M"
635,639c729
< "Q9JHL0-1","25153696","Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology.","PloS one","2014","Polakovicova I, Draberova L, Simicek M, Draber P"
< "Q9JHL0-1","24819605","Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation.","PloS one","2014","Nunez B, Martinez de Mena R, Obregon MJ, Font-Llitjos M, Nunes V, Palacin M, Dumitrescu AM, Morte B, Bernal J"
< "Q9JHL0-1","23675302","LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-gamma production by repressing beta-catenin activation in dendritic cells.","PLoS pathogens","2013 May","Orr SJ, Burg AR, Chan T, Quigley L, Jones GW, Ford JW, Hodge D, Razzook C, Sarhan J, Jones YL, Whittaker GC, Boelte KC, Lyakh L, Cardone M, O'Connor GM, Tan C, Li H, Anderson SK, Jones SA, Zhang W, Taylor PR, Trinchieri G, McVicar DW"
< "Q9JHL0-1","15477348","Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.","The Journal of experimental medicine","2004 Oct 18","Volna P, Lebduska P, Draberova L, Simova S, Heneberg P, Boubelik M, Bugajev V, Malissen B, Wilson BS, Horejsi V, Malissen M, Draber P"
< "O54834-1","11668396","Analysis of Mid1, Hccs, Arhgap6, and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf) mutant mice.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Oct","Cormier TA, Prakash SK, Magner DB, Zoghbi HY, Van den Veyver IB"
---
> "Q6P6N5-1","12646235","Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation.","Biochemical and biophysical research communications","2003 Mar 21","Kato R, Nonami A, Taketomi T, Wakioka T, Kuroiwa A, Matsuda Y, Yoshimura A"
640a731,733
> "P28659-1","30158053","CELF1 contributes to aberrant alternative splicing patterns in the type 1 diabetic heart.","Biochemical and biophysical research communications","2018 Sep 18","Belanger K, Nutter CA, Li J, Tasnim S, Liu P, Yu P, Kuyumcu-Martinez MN"
> "P28659-1","28874395","CELF1 Mediates Connexin 43 mRNA Degradation in Dilated Cardiomyopathy.","Circulation research","2017 Oct 27","Chang KT, Cheng CF, King PC, Liu SY, Wang GS"
> "P28659-1","28763438","Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.","PLoS biology","2017 Aug","Bai Z, Chai XR, Yoon MJ, Kim HJ, Lo KA, Zhang ZC, Xu D, Siang DTC, Walet ACE, Xu SH, Chia SY, Chen P, Yang H, Ghosh S, Sun L"
654d746
< "Q3UA16-1","21084868","Perturbation of Spc25 expression affects meiotic spindle organization, chromosome alignment and spindle assembly checkpoint in mouse oocytes.","Cell cycle (Georgetown, Tex.)","2010 Nov 15","Sun SC, Lee SE, Xu YN, Kim NH"
655a748,752
> "Q9WUH2-3","29565736","Smad ubiquitylation regulatory factor 1 promotes LIM-homeobox gene 9 degradation and represses testosterone production in Leydig cells.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Sep","Hu F, Zhu Q, Sun B, Cui C, Li C, Zhang L"
> "Q9WUH2-3","28456934","Lhx9 Is Required for the Development of Retinal Nitric Oxide-Synthesizing Amacrine Cell Subtype.","Molecular neurobiology","2018 Apr","Balasubramanian R, Bui A, Dong X, Gan L"
> "Q9D486-1","27650733","Repression of CMIP transcription by WT1 is relevant to podocyte health.","Kidney international","2016 Dec","Moktefi A, Zhang SY, Vachin P, Ory V, Henique C, Audard V, Rucker-Martin C, Gouadon E, Eccles M, Schedl A, Heidet L, Ollero M, Sahali D, Pawlak A"
> "Q9D486-1","23200848","Inhibition of nephrin activation by c-mip through Csk-Cbp-Fyn axis plays a critical role in Angiotensin II-induced podocyte damage.","Cellular signalling","2013 Mar","Yu L, Lin Q, Feng J, Dong X, Chen W, Liu Q, Ye J"
> "Q9D486-1","20808911","A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.","PloS one","2010 Aug 17","Li Z, Mulligan MK, Wang X, Miles MF, Lu L, Williams RW"
658,663d754
< "Q6P1G2-1","29166607","Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function.","Cell reports","2017 Nov 21","Zhou Z, Yang X, He J, Liu J, Wu F, Yu S, Liu Y, Lin R, Liu H, Cui Y, Zhou C, Wang X, Wu J, Cao S, Guo L, Lin L, Wang T, Peng X, Qiang B, Hutchins AP, Pei D, Chen J"
< "Q6P1G2-1","28319097","Long noncoding RNA lncKdm2b is required for ILC3 maintenance by initiation of Zfp292 expression.","Nature immunology","2017 May","Liu B, Ye B, Yang L, Zhu X, Huang G, Zhu P, Du Y, Wu J, Qin X, Chen R, Tian Y, Fan Z"
< "Q6P1G2-1","24856970","Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.","Cell","2014 Jun 5","Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LL, Ito S, Cooper S, Kondo K, Koseki Y, Ishikura T, Long HK, Sheahan TW, Brockdorff N, Kessler BM, Koseki H, Klose RJ"
< "Q6P1G2-1","21220025","Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.","Molecular and cellular neurosciences","2011 Mar","Fukuda T, Tokunaga A, Sakamoto R, Yoshida N"
< "Q6P1G2-1","18836456","The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b).","Nature structural &amp; molecular biology","2008 Nov","He J, Kallin EM, Tsukada Y, Zhang Y"
< "Q6P1G2-1","17296600","Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.","Molecular &amp; cellular proteomics : MCP","2007 May","Sanchez C, Sanchez I, Demmers JA, Rodriguez P, Strouboulis J, Vidal M"
666c757
< "Q8CBW3-1","26428302","The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.","Cell communication and signaling : CCS","2015 Oct 1","Sekino S, Kashiwagi Y, Kanazawa H, Takada K, Baba T, Sato S, Inoue H, Kojima M, Tani K"
---
> "B3GLJ6-1","18387948","PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.","The Journal of biological chemistry","2008 Jun 13","Levitin F, Weiss M, Hahn Y, Stern O, Papke RL, Matusik R, Nandana SR, Ziv R, Pichinuk E, Salame S, Bera T, Vincent J, Lee B, Pastan I, Wreschner DH"
668a760,763
> "Q925P2-1","27161904","CEACAM2 positively regulates integrin alphaIIbbeta3-mediated platelet functions.","Platelets","2016 Dec","Alshahrani MM, Kyriacou RP, O'Malley CJ, Heinrich G, Najjar SM, Jackson DE"
> "Q925P2-1","26586918","Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2).","The Journal of biological chemistry","2016 Jan 8","Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, Kim JK, Giovannucci DR, Najjar SM"
> "Q925P2-1","25085348","CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.","Blood","2014 Oct 9","Alshahrani MM, Yang E, Yip J, Ghanem SS, Abdallah SL, deAngelis AM, O'Malley CJ, Moheimani F, Najjar SM, Jackson DE"
> "Q925P2-1","24948196","CEACAM2-L on spermatids interacts with poliovirus receptor on Sertoli cells in mouse seminiferous epithelium.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2014 Sep","Salaheldeen E, Howida A, Wakayama T, Iida H"
674,676d768
< "Q30KP6-1","26987518","Targeted inactivation of the mouse epididymal beta-defensin 41 alters sperm flagellar beat pattern and zona pellucida binding.","Molecular and cellular endocrinology","2016 May 15","Bjorkgren I, Alvarez L, Blank N, Balbach M, Turunen H, Laajala TD, Toivanen J, Krutskikh A, Wahlberg N, Huhtaniemi I, Poutanen M, Wachten D, Sipila P"
< "Q30KP6-1","16023745","Discovery and characterization of new epididymis-specific beta-defensins in mice.","Biochimica et biophysica acta","2005 Jul 25","Jalkanen J, Huhtaniemi I, Poutanen M"
< "Q8R3P2-1","16923970","T cells develop normally in the absence of both Deltex1 and Deltex2.","Molecular and cellular biology","2006 Oct","Lehar SM, Bevan MJ"
678a771,776
> "P97443-1","30061404","Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.","Proceedings of the National Academy of Sciences of the United States of America","2018 Aug 14","Warren JS, Tracy CM, Miller MR, Makaju A, Szulik MW, Oka SI, Yuzyuk TN, Cox JE, Kumar A, Lozier BK, Wang L, Llana JG, Sabry AD, Cawley KM, Barton DW, Han YH, Boudina S, Fiehn O, Tucker HO, Zaitsev AV, Franklin S"
> "P97443-1","29499397","siRNA-mediated inhibition of skNAC and Smyd1 expression disrupts myofibril organization: Immunofluorescence and electron microscopy study in C2C12 cells.","Micron (Oxford, England : 1993)","2018 May","Berkholz J, Eberle R, Boller K, Munz B"
> "P97443-1","27663768","The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.","American journal of physiology. Heart and circulatory physiology","2016 Nov 1","Franklin S, Kimball T, Rasmussen TL, Rosa-Garrido M, Chen H, Tran T, Miller MR, Gray R, Jiang S, Ren S, Wang Y, Tucker HO, Vondriska TM"
> "P97443-1","26935107","Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray.","Disease models &amp; mechanisms","2016 Mar","Stewart MD, Lopez S, Nagandla H, Soibam B, Benham A, Nguyen J, Valenzuela N, Wu HJ, Burns AR, Rasmussen TL, Tucker HO, Schwartz RJ"
> "P97443-1","12011100","m-Bop, a repressor protein essential for cardiogenesis, interacts with skNAC, a heart- and muscle-specific transcription factor.","The Journal of biological chemistry","2002 Jul 19","Sims RJ 3rd, Weihe EK, Zhu L, O'Malley S, Harriss JV, Gottlieb PD"
> "P97443-1","11923873","Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.","Nature genetics","2002 May","Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D"
689a788,800
> "Q65Z40-1","27760328","Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1gamma-WAPL Axis in the Mouse.","Cell reports","2016 Oct 18","Brieno-Enriquez MA, Moak SL, Toledo M, Filter JJ, Gray S, Barbero JL, Cohen PE, Holloway JK"
> "Q08943-1","30344095","The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage.","Molecular cell","2018 Dec 6","Piquet S, Le Parc F, Bai SK, Chevallier O, Adam S, Polo SE"
> "Q08943-1","29953487","Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene.","PloS one","2018","Sandlesh P, Juang T, Safina A, Higgins MJ, Gurova KV"
> "Q08943-1","26842758","Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability.","Nature communications","2016 Feb 4","Husain A, Begum NA, Taniguchi T, Taniguchi H, Kobayashi M, Honjo T"
> "Q9D956-1","20164257","Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.","Molecular biology of the cell","2010 Apr 1","Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR"
> "Q61584-1","30770808","Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy.","Nature communications","2019 Feb 15","Estan MC, Fernandez-Nunez E, Zaki MS, Esteban MI, Donkervoort S, Hawkins C, Caparros-Martin JA, Saade D, Hu Y, Bolduc V, Chao KR, Nevado J, Lamuedra A, Largo R, Herrero-Beaumont G, Regadera J, Hernandez-Chico C, Tizzano EF, Martinez-Glez V, Carvajal JJ, Zong R, Nelson DL, Otaify GA, Temtamy S, Aglan M, Issa M, Bonnemann CG, Lapunzina P, Yoon G, Ruiz-Perez VL"
> "Q61584-1","30397356","Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.","Nature medicine","2018 Dec","Sun L, Xie C, Wang G, Wu Y, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C"
> "Q61584-1","29730159","FXR deletion in hepatocytes does not affect the severity of alcoholic liver disease in mice.","Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver","2018 Oct","Zhang M, Kong B, Huang M, Wan R, Armstrong LE, Schumacher JD, Rizzolo D, Chow MD, Lee YH, Guo GL"
> "Q61584-1","11178106","Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast.","BMC genetics","2000","Dube M, Huot ME, Khandjian EW"
> "C0LLJ0-1","28189564","H7N9 Influenza A Virus Exhibits Importin-alpha7-Mediated Replication in the Mammalian Respiratory Tract.","The American journal of pathology","2017 Apr","Bertram S, Thiele S, Dreier C, Resa-Infante P, Preuss A, van Riel D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD, Gabriel G"
> "C0LLJ0-1","20699224","Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.","The Journal of biological chemistry","2010 Oct 22","Hu J, Wang F, Yuan Y, Zhu X, Wang Y, Zhang Y, Kou Z, Wang S, Gao S"
> "C0LLJ0-1","20701745","Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.","BMC cell biology","2010 Aug 11","Kelley JB, Talley AM, Spencer A, Gioeli D, Paschal BM"
> "Q9ER69-1","26190105","A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing.","Cell reports","2015 Jul 28","Moindrot B, Cerase A, Coker H, Masui O, Grijzenhout A, Pintacuda G, Schermelleh L, Nesterova TB, Brockdorff N"
692,697d802
< "Q2TV84-1","29854741","Different Activity Patterns in Retinal Ganglion Cells of TRPM1 and mGluR6 Knockout Mice.","BioMed research international","2018","Takeuchi H, Horie S, Moritoh S, Matsushima H, Hori T, Kimori Y, Kitano K, Tsubo Y, Tachibana M, Koike C"
< "Q2TV84-1","28899920","The TRPM1 Channel Is Required for Development of the Rod ON Bipolar Cell-AII Amacrine Cell Pathway in the Retinal Circuit.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Oct 11","Kozuka T, Chaya T, Tamalu F, Shimada M, Fujimaki-Aoba K, Kuwahara R, Watanabe SI, Furukawa T"
< "Q2TV84-1","19966281","TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.","Proceedings of the National Academy of Sciences of the United States of America","2010 Jan 5","Koike C, Obara T, Uriu Y, Numata T, Sanuki R, Miyata K, Koyasu T, Ueno S, Funabiki K, Tani A, Ueda H, Kondo M, Mori Y, Tachibana M, Furukawa T"
< "Q9DCB1-1","26112184","Expression, regulation and function of Hmgn3 during decidualization in mice.","Molecular and cellular endocrinology","2015 Sep 15","Li DD, Guo CH, Yue L, Duan CC, Yang ZQ, Cao H, Guo B, Yue ZP"
< "Q9DCB1-1","23620591","High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.","The Journal of biological chemistry","2013 Jun 7","Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L, Bohla A, Holter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T, Adamski J, Beckers J, Busch DH, Eickelberg O, Klopstock T, Ollert M, Stoger T, Wolf E, Wurst W, Yildirim AO, Zimmer A, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Garfinkel B, Orly J, Ovcharenko I, Bustin M"
< "Q9DCB1-1","15082770","Chromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1.","Molecular and cellular biology","2004 May","West KL, Castellini MA, Duncan MK, Bustin M"
699d803
< "Q61411-1","30655611","WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.","Nature communications","2019 Jan 17","Jeong WJ, Park JC, Kim WS, Ro EJ, Jeon SH, Lee SK, Park YN, Min DS, Choi KY"
703a808
> "Q9CWR2-1","15235609","SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.","Nature cell biology","2004 Aug","Hamamoto R, Furukawa Y, Morita M, Iimura Y, Silva FP, Li M, Yagyu R, Nakamura Y"
708,709c813
< "Q921U8-1","18678771","Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice.","Circulation","2008 Aug 19","Rensen SS, Niessen PM, van Deursen JM, Janssen BJ, Heijman E, Hermeling E, Meens M, Lie N, Gijbels MJ, Strijkers GJ, Doevendans PA, Hofker MH, De Mey JG, van Eys GJ"
< "Q921U8-1","16285958","Smoothelin-a is essential for functional intestinal smooth muscle contractility in mice.","Gastroenterology","2005 Nov","Niessen P, Rensen S, van Deursen J, De Man J, De Laet A, Vanderwinden JM, Wedel T, Baker D, Doevendans P, Hofker M, Gijbels M, van Eys G"
---
> "Q9D410-1","17660561","Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.","Genetics","2007 Sep","Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH"
713,714c817,819
< "Q8VCF1-1","28330694","CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma.","Molecular therapy : the journal of the American Society of Gene Therapy","2017 May 3","Xing Y, Wen X, Ding X, Fan J, Chai P, Jia R, Ge S, Qian G, Zhang H, Fan X"
< "Q8VCF1-1","22451650","Ca2+-activated nucleotidase 1, a novel target gene for the transcriptional repressor DREAM (downstream regulatory element antagonist modulator), is involved in protein folding and degradation.","The Journal of biological chemistry","2012 May 25","Cali T, Fedrizzi L, Ottolini D, Gomez-Villafuertes R, Mellstrom B, Naranjo JR, Carafoli E, Brini M"
---
> "Q8BXK8-1","15381706","AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.","The Journal of biological chemistry","2004 Nov 19","Meurer S, Pioch S, Wagner K, Muller-Esterl W, Gross S"
> "Q8R0S4-3","27003325","Loss of the calcium channel beta4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice.","The European journal of neuroscience","2016 Jun","Benedetti B, Benedetti A, Flucher BE"
> "Q8R0S4-3","24875574","The juvenile myoclonic epilepsy mutant of the calcium channel beta(4) subunit displays normal nuclear targeting in nerve and muscle cells.","Channels (Austin, Tex.)","2014","Etemad S, Campiglio M, Obermair GJ, Flucher BE"
715a821
> "P61600-1","22101279","Spatio-temporal expression pattern of the NatB complex, Nat5/Mdm20 in the developing mouse brain: implications for co-operative versus non-co-operative actions of Mdm20 and Nat5.","Gene expression patterns : GEP","2012 Jan-Feb","Ohyama K, Yasuda K, Onga K, Kakizuka A, Mori N"
716a823
> "P14824-1","28712927","Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation.","Experimental cell research","2017 Sep 15","Cairns R, Alvarez-Guaita A, Martinez-Saludes I, Wason SJ, Hanh J, Nagarajan SR, Hosseini-Beheshti E, Monastyrskaya K, Hoy AJ, Buechler C, Enrich C, Rentero C, Grewal T"
724,725c831,833
< "A8Y5H7-1","15531584","The Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs.","The Journal of biological chemistry","2005 Jan 28","Kostenko EV, Mahon GM, Cheng L, Whitehead IP"
< "Q3U3C9-1","16169686","Temporal change in mKIAA gene expression during the early stage of retinoic acid-induced neurite outgrowth.","Gene","2005 Dec 30","Imai K, Kawai M, Tada M, Nagase T, Ohara O, Koga H"
---
> "P60670-1","26112410","The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-kappaB Signaling via Partial Degradation of the NF-kappaB Subunit p100.","The Journal of biological chemistry","2015 Aug 7","Zhang Z, Wang Y, Li C, Shi Z, Hao Q, Wang W, Song X, Zhao Y, Jiao S, Zhou Z"
> "P60670-1","17491009","Detailed structural insights into the p97-Npl4-Ufd1 interface.","The Journal of biological chemistry","2007 Jul 20","Isaacson RL, Pye VE, Simpson P, Meyer HH, Zhang X, Freemont PS, Matthews S"
> "P60670-1","16103111","Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors.","The Journal of biological chemistry","2005 Oct 14","Alzayady KJ, Panning MM, Kelley GG, Wojcikiewicz RJ"
739,740c847
< "Q62315-1","30119689","JARID2 and the PRC2 complex regulate skeletal muscle differentiation through regulation of canonical Wnt signaling.","Epigenetics &amp; chromatin","2018 Aug 17","Adhikari A, Davie J"
< "Q62315-1","29891551","Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.","The Journal of biological chemistry","2018 Jul 27","Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y"
---
> "Q8BTY1-1","20482848","Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases.","BMC biochemistry","2010 May 19","Han Q, Cai T, Tagle DA, Li J"
744a852,853
> "Q149L0-1","29106393","DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma.","Oncogene","2018 Feb 22","Zhou Y, Wang L, Ban X, Zeng T, Zhu Y, Li M, Guan XY, Li Y"
> "Q149L0-1","23036705","Molecular and functional evolution of human DHRS2 and DHRS4 duplicated genes.","Gene","2012 Dec 15","Gabrielli F, Tofanelli S"
746a856,859
> "Q8K4K6-1","26549575","Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.","Molecular genetics and metabolism","2015 Dec","Zano SP, Pate C, Frank M, Rock CO, Jackowski S"
> "Q8K4K6-1","24781151","Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance.","Diabetologia","2014 Jul","Leonardi R, Rock CO, Jackowski S"
> "Q8K4K6-1","23343762","p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.","Cell cycle (Georgetown, Tex.)","2013 Mar 1","Wang SJ, Yu G, Jiang L, Li T, Lin Q, Tang Y, Gu W"
> "Q8K4K6-1","20559429","Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state.","PloS one","2010 Jun 14","Leonardi R, Rehg JE, Rock CO, Jackowski S"
747a861
> "Q9D700-1","24548998","The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth.","Nature communications","2014","Kim H, Lee HJ, Oh Y, Choi SG, Hong SH, Kim HJ, Lee SY, Choi JW, Su Hwang D, Kim KS, Kim HJ, Zhang J, Youn HJ, Noh DY, Jung YK"
749a864
> "Q3UVR3-1","23141541","The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.","Cell","2012 Nov 9","Goetz SC, Liem KF Jr, Anderson KV"
761a877
> "Q9D2P8-1","26801084","MOBP levels are regulated by Fyn kinase and affect the morphological differentiation of oligodendrocytes.","Journal of cell science","2016 Mar 1","Schafer I, Muller C, Luhmann HJ, White R"
767a884,886
> "Q80U72-1","30083817","Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells.","Journal of cancer research and clinical oncology","2018 Oct","Dash BP, Schnoder TM, Kathner C, Mohr J, Weinert S, Herzog C, Godavarthy PS, Zanetti C, Perner F, Braun-Dullaeus R, Hartleben B, Huber TB, Walz G, Naumann M, Ellis S, Vasioukhin V, Kahne T, Krause DS, Heidel FH"
> "Q80U72-1","12499390","Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse.","Human molecular genetics","2003 Jan 15","Murdoch JN, Henderson DJ, Doudney K, Gaston-Massuet C, Phillips HM, Paternotte C, Arkell R, Stanier P, Copp AJ"
> "Q80U72-1","12112872","A new allele of Gli3 and a new mutation, circletail (Crc), resulting from a single transgenic experiment.","Genesis (New York, N.Y. : 2000)","2002 Jun","Rachel RA, Wellington SJ, Warburton D, Mason CA, Beermann F"
769a889
> "Q6P5G0-1","16973613","Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.","The Journal of biological chemistry","2006 Nov 17","Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M"
778,781c898,899
< "Q3U0P1-1","28240985","A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.","eLife","2017 Feb 27","Luijsterburg MS, Typas D, Caron MC, Wiegant WW, van den Heuvel D, Boonen RA, Couturier AM, Mullenders LH, Masson JY, van Attikum H"
< "Q3U0P1-1","20484223","Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.","Human molecular genetics","2010 Aug 1","Rantakari P, Nikkila J, Jokela H, Ola R, Pylkas K, Lagerbohm H, Sainio K, Poutanen M, Winqvist R"
< "P58659-1","25122090","EVA-1 functions as an UNC-40 Co-receptor to enhance attraction to the MADD-4 guidance cue in Caenorhabditis elegans.","PLoS genetics","2014 Aug","Chan KK, Seetharaman A, Bagg R, Selman G, Zhang Y, Kim J, Roy PJ"
< "P58659-1","24040182","The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system.","PloS one","2013","James G, Foster SR, Key B, Beverdam A"
---
> "Q3UEG6-1","27752063","A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2.","Scientific reports","2016 Oct 18","Rodionov RN, Oppici E, Martens-Lobenhoffer J, Jarzebska N, Brilloff S, Burdin D, Demyanov A, Kolouschek A, Leiper J, Maas R, Cellini B, Weiss N, Bode-Boger SM"
> "Q3UEG6-1","23023372","Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure.","Arteriosclerosis, thrombosis, and vascular biology","2012 Dec","Caplin B, Wang Z, Slaviero A, Tomlinson J, Dowsett L, Delahaye M, Salama A, Wheeler DC, Leiper J"
788a907,909
> "Q4VBE4-1","26091521","Pikachurin Protein Required for Increase of Cone Electroretinogram B-Wave during Light Adaptation.","PloS one","2015","Nagaya M, Ueno S, Kominami T, Nakanishi A, Koyasu T, Kondo M, Furukawa T, Terasaki H"
> "Q4VBE4-1","21129441","Pikachurin interaction with dystroglycan is diminished by defective O-mannosyl glycosylation in congenital muscular dystrophy models and rescued by LARGE overexpression.","Neuroscience letters","2011 Feb 1","Hu H, Li J, Zhang Z, Yu M"
> "Q4VBE4-1","20682766","Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization.","The Journal of biological chemistry","2010 Oct 8","Kanagawa M, Omori Y, Sato S, Kobayashi K, Miyagoe-Suzuki Y, Takeda S, Endo T, Furukawa T, Toda T"
791a913
> "Q91VU0-1","29871931","Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1).","The Journal of biological chemistry","2018 Jul 20","Noguchi K, Dincman TA, Dalton AC, Howley BV, McCall BJ, Mohanty BK, Howe PH"
796a919,920
> "Q8VHI6-1","28794159","p63alpha protein up-regulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion.","The Journal of biological chemistry","2017 Sep 22","Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, Zhu J, Wu XR, Huang H, Huang C"
> "O54689-1","29695802","Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment.","Nature communications","2018 Apr 25","Wunderlich CM, Ackermann PJ, Ostermann AL, Adams-Quack P, Vogt MC, Tran ML, Nikolajev A, Waisman A, Garbers C, Theurich S, Mauer J, Hovelmeyer N, Wunderlich FT"
797a922
> "Q9JKL1-1","30253862","PK2beta ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor.","Neuropeptides","2018 Oct","Lattanzi R, Maftei D, Negri L, Fusco I, Miele R"
803a929,930
> "O09012-1","26086376","Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts.","Autophagy","2015","Nordgren M, Francisco T, Lismont C, Hennebel L, Brees C, Wang B, Van Veldhoven PP, Azevedo JE, Fransen M"
> "O09012-1","22458306","Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system.","Journal of neuroinflammation","2012 Mar 29","Bottelbergs A, Verheijden S, Van Veldhoven PP, Just W, Devos R, Baes M"
806,808c933,934
< "O54931-1","26432469","A-kinase anchoring protein 2 is required for calcitonin-mediated invasion of cancer cells.","Endocrine-related cancer","2016 Jan","Thakkar A, Aljameeli A, Thomas S, Shah GV"
< "O54931-1","22095752","AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency.","EMBO molecular medicine","2012 Jan","Gold MG, Reichow SL, O'Neill SE, Weisbrod CR, Langeberg LK, Bruce JE, Gonen T, Scott JD"
< "O54931-1","16260760","Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchange.","Protein science : a publication of the Protein Society","2005 Dec","Burns-Hamuro LL, Hamuro Y, Kim JS, Sigala P, Fayos R, Stranz DD, Jennings PA, Taylor SS, Woods VL Jr"
---
> "Q9D7P9-1","26220980","Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2015 Nov","Niehaus JZ, Good M, Jackson LE, Ozolek JA, Silverman GA, Luke CJ"
> "Q3V3R1-1","19948730","Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos.","The Journal of biological chemistry","2010 Feb 12","Pike ST, Rajendra R, Artzt K, Appling DR"
810a937
> "Q62447-1","26042770","mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).","PloS one","2015","Feng D, Youn DY, Zhao X, Gao Y, Quinn WJ 3rd, Xiaoli AM, Sun Y, Birnbaum MJ, Pessin JE, Yang F"
821,822c948
< "Q8K2Q9-1","26849555","CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization.","PloS one","2016","Nawaz MS, Giarda E, Bedogni F, La Montanara P, Ricciardi S, Ciceri D, Alberio T, Landsberger N, Rusconi L, Kilstrup-Nielsen C"
< "Q8K2Q9-1","23864681","Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2013 Jul 17","Sapir T, Levy T, Sakakibara A, Rabinkov A, Miyata T, Reiner O"
---
> "P58269-1","18765789","Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.","Genes &amp; development","2008 Sep 1","Lange M, Kaynak B, Forster UB, Tonjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S"
828c954,955
< "Q6P1H6-1","25343476","Zinc finger protein Zfp335 is required for the formation of the naive T cell compartment.","eLife","2014 Oct 24","Han BY, Wu S, Foo CS, Horton RM, Jenne CN, Watson SR, Whittle B, Goodnow CC, Cyster JG"
---
> "Q8BK06-1","27197753","F-box only protein 9 is an E3 ubiquitin ligase of PPARgamma.","Experimental &amp; molecular medicine","2016 May 20","Lee KW, Kwak SH, Koo YD, Cho YK, Lee HM, Jung HS, Cho YM, Park YJ, Chung SS, Park KS"
> "Q8BK06-1","20459822","The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors.","Molecular cancer","2010 May 11","Sturgill TW, Stoddard PB, Cohn SM, Mayo MW"
834a962,967
> "Q9QYY1-1","24829417","IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin.","Journal of immunology (Baltimore, Md. : 1950)","2014 Jun 15","Foster AM, Baliwag J, Chen CS, Guzman AM, Stoll SW, Gudjonsson JE, Ward NL, Johnston A"
> "Q61142-1","23894536","A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption.","PloS one","2013","Chew TG, Peaston A, Lim AK, Lorthongpanich C, Knowles BB, Solter D"
> "Q61142-1","21960006","Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes.","EMBO reports","2011 Oct 28","Wang W, Chen Z, Mao Z, Zhang H, Ding X, Chen S, Zhang X, Xu R, Zhu B"
> "Q61142-1","18645677","Characterization of Spindlin1 isoform2 in mouse testis.","Asian journal of andrology","2008 Sep","Zhang KM, Wang YF, Huo R, Bi Y, Lin M, Sha JH, Zhou ZM"
> "Q61142-1","18201843","Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis.","Gene","2008 Feb 29","Yuan H, Zhang P, Qin L, Chen L, Shi S, Lu Y, Yan F, Bai C, Nan X, Liu D, Li Y, Yue W, Pei X"
> "Q61142-1","16098913","Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells.","Biochemical and biophysical research communications","2005 Sep 23","Gao Y, Yue W, Zhang P, Li L, Xie X, Yuan H, Chen L, Liu D, Yan F, Pei X"
838,840d970
< "Q8BFW7-1","23447672","A complex containing LPP and alpha-actinin mediates TGFbeta-induced migration and invasion of ErbB2-expressing breast cancer cells.","Journal of cell science","2013 May 1","Ngan E, Northey JJ, Brown CM, Ursini-Siegel J, Siegel PM"
< "Q8BFW7-1","22886954","TGF-beta1-induced LPP expression dependant on Rho kinase during differentiation and migration of bone marrow-derived smooth muscle progenitor cells.","Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban","2012 Aug","Qu Z, Yu J, Ruan Q"
< "Q8BFW7-1","12441356","The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein.","The Journal of biological chemistry","2003 Jan 24","Petit MM, Meulemans SM, Van de Ven WJ"
850a981
> "Q9D8Z1-1","26924529","Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures.","American journal of human genetics","2016 Mar 3","Knierim E, Hirata H, Wolf NI, Morales-Gonzalez S, Schottmann G, Tanaka Y, Rudnik-Schoneborn S, Orgeur M, Zerres K, Vogt S, van Riesen A, Gill E, Seifert F, Zwirner A, Kirschner J, Goebel HH, Hubner C, Stricker S, Meierhofer D, Stenzel W, Schuelke M"
853c984,985
< "Q6NSU3-1","29483533","Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.","Nature communications","2018 Feb 26","Yang CP, Li X, Wu Y, Shen Q, Zeng Y, Xiong Q, Wei M, Chen C, Liu J, Huo Y, Li K, Xue G, Yao YG, Zhang C, Li M, Chen Y, Luo XJ"
---
> "Q9JJJ7-1","29066530","Regulation of porcupine-dependent Wnt signaling is essential for uterine development and function.","Reproduction (Cambridge, England)","2018 Jan","Farah O, Biechele S, Rossant J, Dufort D"
> "Q9JJJ7-1","29036275","Porcupine-dependent Wnt activity within the uterine epithelium is essential for fertility.","Biology of reproduction","2017 Nov 1","Farah O, Biechele S, Rossant J, Dufort D"
854a987
> "P16563-1","26786179","Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders.","Molecular human reproduction","2016 Apr","Brukman NG, Miyata H, Torres P, Lombardo D, Caramelo JJ, Ikawa M, Da Ros VG, Cuasnicu PS"
859,862c992
< "O70494-1","28359915","Sp3 controls fibroblast growth factor receptor 4 gene activity during myogenic differentiation.","Gene","2017 Jun 20","Cavanaugh E, DiMario JX"
< "O70494-1","28522827","Involvement of GATA1 and Sp3 in the activation of the murine STING gene promoter in NIH3T3 cells.","Scientific reports","2017 May 18","Xu YY, Jin R, Zhou GP, Xu HG"
< "O70494-1","27143785","Transcription factors YY1, Sp1 and Sp3 modulate dystrophin Dp71 gene expression in hepatic cells.","The Biochemical journal","2016 Jul 1","Penuelas-Urquides K, Becerril-Esquivel C, Mendoza-de-Leon LC, Silva-Ramirez B, Davila-Velderrain J, Cisneros B, de Leon MB"
< "O70494-1","11472836","Impaired ossification in mice lacking the transcription factor Sp3.","Mechanisms of development","2001 Aug","Gollner H, Dani C, Phillips B, Philipsen S, Suske G"
---
> "Q91WE2-1","26497270","Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle.","Gene","2016 Jan 15","Waddell DS, Duffin PJ, Haddock AN, Triplett VE, Saredy JJ, Kakareka KM, Eldredge JT"
864a995,996
> "Q8C7Q4-1","30327195","RBM4a modulates the impact of PRDM16 on development of brown adipocytes through an alternative splicing mechanism.","Biochimica et biophysica acta. Molecular cell research","2018 Nov","Chi YL, Lin JC"
> "Q8C7Q4-1","30200638","RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis.","International journal of molecular sciences","2018 Sep 6","Peng HY, Liang YC, Tan TH, Chuang HC, Lin YJ, Lin JC"
866a999,1000
> "P47757-1","20969875","The interaction of capping protein with the barbed end of the actin filament.","Journal of molecular biology","2010 Dec 17","Kim T, Cooper JA, Sept D"
> "P47757-1","19806181","Capzb2 interacts with beta-tubulin to regulate growth cone morphology and neurite outgrowth.","PLoS biology","2009 Oct","Davis DA, Wilson MH, Giraud J, Xie Z, Tseng HC, England C, Herscovitz H, Tsai LH, Delalle I"
869,882c1003,1005
< "Q69ZU8-1","25218921","Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.","Developmental biology","2014 Nov 1","Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P"
< "Q69ZU8-1","20827749","Expression and proliferation-promoting role of Diversin in the neuronally committed precursor cells migrating in the adult mouse brain.","Stem cells (Dayton, Ohio)","2010 Nov","Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida YS, Ogura T, Otsuka T, Okano H, Sawamoto K"
< "Q69ZU8-1","19789178","Centrosomal localization of Diversin and its relevance to Wnt signaling.","Journal of cell science","2009 Oct 15","Itoh K, Jenny A, Mlodzik M, Sokol SY"
< "Q69ZU8-1","12203740","Expression of the ankyrin repeat domain 6 gene (Ankrd6) during mouse brain development.","Developmental dynamics : an official publication of the American Association of Anatomists","2002 Aug","Tissir F, Bar I, Goffinet AM, Lambert De Rouvroit C"
< "Q9ESL4-1","27598200","A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.","Toxins","2016 Sep 2","Jandhyala DM, Wong J, Mantis NJ, Magun BE, Leong JM, Thorpe CM"
< "Q9ESL4-1","26755636","Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.","Genome research","2016 Feb","Spielmann M, Kakar N, Tayebi N, Leettola C, Nurnberg G, Sowada N, Lupianez DG, Harabula I, Flottmann R, Horn D, Chan WL, Wittler L, Yilmaz R, Altmuller J, Thiele H, van Bokhoven H, Schwartz CE, Nurnberg P, Bowie JU, Ahmad J, Kubisch C, Mundlos S, Borck G"
< "Q9ESL4-1","24789282","Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains.","PloS one","2014","Kobayashi M, Ohno T, Ihara K, Murai A, Kumazawa M, Hoshino H, Iwanaga K, Iwai H, Hamana Y, Ito M, Ohno K, Horio F"
< "Q9ESL4-1","15737997","Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA.","The Journal of biological chemistry","2005 May 13","Wang X, Mader MM, Toth JE, Yu X, Jin N, Campbell RM, Smallwood JK, Christe ME, Chatterjee A, Goodson T Jr, Vlahos CJ, Matter WF, Bloem LJ"
< "Q9ESL4-1","15684425","Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.","The Journal of biological chemistry","2005 Apr 8","Choi HS, Choi BY, Cho YY, Zhu F, Bode AM, Dong Z"
< "Q9ESL4-1","12761180","Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.","Journal of biochemistry","2003 Feb","Takahashi M, Gotoh Y, Isagawa T, Nishimura T, Goyama E, Kim HS, Mukai H, Ono Y"
< "Q8K341-1","29703898","TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.","Nature communications","2018 Apr 27","Shah N, Kumar S, Zaman N, Pan CC, Bloodworth JC, Lei W, Streicher JM, Hempel N, Mythreye K, Lee NY"
< "Q8K341-1","28687926","ATAT1 is essential for regulation of homeostasis-retaining cellular responses in corticotrophs along hypothalamic-pituitary-adrenal axis.","Cell and tissue research","2017 Oct","Nakakura T, Suzuki T, Torii S, Asano-Hoshino A, Nekooki-Machida Y, Tanaka H, Arisawa K, Nishijima Y, Susa T, Okazaki T, Kiuchi Y, Hagiwara H"
< "Q8K341-1","27976998","Acetylated tubulin is essential for touch sensation in mice.","eLife","2016 Dec 13","Morley SJ, Qi Y, Iovino L, Andolfi L, Guo D, Kalebic N, Castaldi L, Tischer C, Portulano C, Bolasco G, Shirlekar K, Fusco CM, Asaro A, Fermani F, Sundukova M, Matti U, Reymond L, De Ninno A, Businaro L, Johnsson K, Lazzarino M, Ries J, Schwab Y, Hu J, Heppenstall PA"
< "Q8K341-1","23126280","Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of alpha-tubulin.","The Biochemical journal","2013 Feb 1","Yang W, Guo X, Thein S, Xu F, Sugii S, Baas PW, Radda GK, Han W"
---
> "P97477-1","29842884","Novel localization of Aurora A kinase in mouse testis suggests multiple roles in spermatogenesis.","Biochemical and biophysical research communications","2018 Sep 3","Johnson ML, Wang R, Sperry AO"
> "Q3UZP0-1","28767685","Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells.","PloS one","2017","Takano K, Kakuki T, Kaneko Y, Kohno T, Kikuchi S, Himi T, Kojima T"
> "Q3UZP0-1","20164257","Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.","Molecular biology of the cell","2010 Apr 1","Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR"
885a1009,1011
> "Q9ESM6-1","28849762","Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.","eLife","2017 Aug 29","van Veen M, Matas-Rico E, van de Wetering K, Leyton-Puig D, Kedziora KM, De Lorenzi V, Stijf-Bultsma Y, van den Broek B, Jalink K, Sidenius N, Perrakis A, Moolenaar WH"
> "Q9ESM6-1","19596859","The developmentally regulated osteoblast phosphodiesterase GDE3 is glycerophosphoinositol-specific and modulates cell growth.","The Journal of biological chemistry","2009 Sep 11","Corda D, Kudo T, Zizza P, Iurisci C, Kawai E, Kato N, Yanaka N, Mariggio S"
> "Q9ESM6-1","12933806","Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation.","The Journal of biological chemistry","2003 Oct 31","Yanaka N, Imai Y, Kawai E, Akatsuka H, Wakimoto K, Nogusa Y, Kato N, Chiba H, Kotani E, Omori K, Sakurai N"
889d1014
< "A2AJL3-1","29220483","Prenatal Exposure to Bisphenol A Disrupts Naturally Occurring Bimodal DNA Methylation at Proximal Promoter of fggy, an Obesity-Relevant Gene Encoding a Carbohydrate Kinase, in Gonadal White Adipose Tissues of CD-1 Mice.","Endocrinology","2018 Feb 1","Taylor JA, Shioda K, Mitsunaga S, Yawata S, Angle BM, Nagel SC, Vom Saal FS, Shioda T"
893a1019
> "Q91YI4-1","30576947","Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and beta-arrestin 2 in inflammatory macrophages.","Molecular immunology","2019 Feb","Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ"
903,904d1028
< "P97434-1","16243315","Inhibition of RhoA-mediated SRF activation by p116Rip.","FEBS letters","2005 Nov 7","Mulder J, Ariaens A, van Horck FP, Moolenaar WH"
< "P97434-1","12732640","p116Rip is a novel filamentous actin-binding protein.","The Journal of biological chemistry","2003 Jul 18","Mulder J, Poland M, Gebbink MF, Calafat J, Moolenaar WH, Kranenburg O"
907,913c1031,1037
< "Q8VBT9-1","25944897","Coordinated Regulation of Vasopressin Inactivation and Glucose Uptake by Action of TUG Protein in Muscle.","The Journal of biological chemistry","2015 Jun 5","Habtemichael EN, Alcazar-Roman A, Rubin BR, Grossi LR, Belman JP, Julca O, Loffler MG, Li H, Chi NW, Samuel VT, Bogan JS"
< "Q8VBT9-1","25453902","Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment.","Cancer cell","2014 Dec 8","Goodwin ML, Jin H, Straessler K, Smith-Fry K, Zhu JF, Monument MJ, Grossmann A, Randall RL, Capecchi MR, Jones KB"
< "Q8VBT9-1","23744065","Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle.","The Journal of biological chemistry","2013 Jul 12","Loffler MG, Birkenfeld AL, Philbrick KM, Belman JP, Habtemichael EN, Booth CJ, Castorena CM, Choi CS, Jornayvaz FR, Gassaway BM, Lee HY, Cartee GD, Philbrick W, Shulman GI, Samuel VT, Bogan JS"
< "Q8VBT9-1","22610098","Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocation.","The Journal of biological chemistry","2012 Jul 6","Bogan JS, Rubin BR, Yu C, Loffler MG, Orme CM, Belman JP, McNally LJ, Hao M, Cresswell JA"
< "Q8VBT9-1","17202135","The glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytes.","The Journal of biological chemistry","2007 Mar 9","Yu C, Cresswell J, Loffler MG, Bogan JS"
< "Q8VBT9-1","14562105","Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking.","Nature","2003 Oct 16","Bogan JS, Hendon N, McKee AE, Tsao TS, Lodish HF"
< "O54918-1","30590105","c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson's Disease.","Neuroscience","2019 Feb 10","Hu K, Huang Q, Liu C, Li Y, Liu Y, Wang H, Li M, Ma S"
---
> "Q8BX10-1","29770487","Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury.","Journal of pineal research","2018 Oct","Zhou H, Li D, Zhu P, Ma Q, Toan S, Wang J, Hu S, Chen Y, Zhang Y"
> "Q8BX10-1","29524517","Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control.","Life sciences","2018 May 1","Hong JM, Lee SM"
> "Q8BX10-1","29438981","Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling.","The Journal of cell biology","2018 Apr 2","Bernkopf DB, Jalal K, Bruckner M, Knaup KX, Gentzel M, Schambony A, Behrens J"
> "Q8BX10-1","26381214","Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.","Nature communications","2015 Sep 18","Kang YJ, Bang BR, Han KH, Hong L, Shim EJ, Ma J, Lerner RA, Otsuka M"
> "Q8BX10-1","25222142","Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.","Nature communications","2014 Sep 15","Lu W, Karuppagounder SS, Springer DA, Allen MD, Zheng L, Chao B, Zhang Y, Dawson VL, Dawson TM, Lenardo M"
> "Q8BX10-1","25012655","A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5.","The Journal of biological chemistry","2014 Sep 5","Wilkins JM, McConnell C, Tipton PA, Hannink M"
> "Q8BX10-1","22265414","The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways.","Cell","2012 Jan 20","Wang Z, Jiang H, Chen S, Du F, Wang X"
916,917c1040,1041
< "Q64338-3","30469494","Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparalpha.","International journal of molecular sciences","2018 Nov 22","Shete V, Liu N, Jia Y, Viswakarma N, Reddy JK, Thimmapaya B"
< "Q64338-3","29860631","A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.","Human genetics","2018 Jul","Wang L, Feng Y, Yan D, Qin L, Grati M, Mittal R, Li T, Sundhari AK, Liu Y, Chapagain P, Blanton SH, Liao S, Liu X"
---
> "Q5DTM8-1","28453857","Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination.","Nucleic acids research","2017 Jul 7","Lee BK, Lee J, Shen W, Rhee C, Chung H, Kim J"
> "Q5DTM8-1","20738173","Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells.","Radiation research","2010 Nov","Chernikova SB, Dorth JA, Razorenova OV, Game JC, Brown JM"
920a1045
> "Q60596-1","29477978","XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity.","DNA repair","2018 Apr","Horton JK, Stefanick DF, Caglayan M, Zhao ML, Janoshazi AK, Prasad R, Gassman NR, Wilson SH"
923a1049,1053
> "Q9D6X5-1","27272163","Disruption of Slc52a3 gene causes neonatal lethality with riboflavin deficiency in mice.","Scientific reports","2016 Jun 8","Yoshimatsu H, Yonezawa A, Yamanishi K, Yao Y, Sugano K, Nakagawa S, Imai S, Omura T, Nakagawa T, Yano I, Masuda S, Inui K, Matsubara K"
> "Q9D6X5-1","26976849","SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.","Human molecular genetics","2016 May 1","Intoh A, Suzuki N, Koszka K, Eggan K"
> "Q9D6X5-1","26660539","Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption.","American journal of physiology. Gastrointestinal and liver physiology","2016 Feb 15","Subramanian VS, Lambrecht N, Lytle C, Said HM"
> "Q8BJ52-1","25074937","Plasticity-related gene 5 promotes spine formation in murine hippocampal neurons.","The Journal of biological chemistry","2014 Sep 5","Coiro P, Stoenica L, Strauss U, Brauer AU"
> "Q8BJ52-1","20032306","Plasticity-related gene 5 (PRG5) induces filopodia and neurite growth and impedes lysophosphatidic acid- and nogo-A-mediated axonal retraction.","Molecular biology of the cell","2010 Feb 15","Broggini T, Nitsch R, Savaskan NE"
925a1056
> "A2A8Z1-1","19413330","Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.","Analytical chemistry","2009 Jun 1","Gauci S, Helbig AO, Slijper M, Krijgsveld J, Heck AJ, Mohammed S"
930a1062,1063
> "P70196-1","30190125","Autoimmune sialadenitis is associated with the upregulation of chemokine/chemokine receptor pairs in T cell-specific TRAF6-deficient mice.","Biochemical and biophysical research communications","2018 Sep 26","Noguchi K, Kamiyama N, Hidano S, Gendo Y, Sonoda A, Ozaki T, Hirose H, Sachi N, Saechue B, Ozaka S, Eshita Y, Mizukami K, Kawano K, Kobayashi T"
> "P70196-1","30103950","Inhibition of TRAF6 alleviates choroidal neovascularization in vivo.","Biochemical and biophysical research communications","2018 Sep 18","Ding D, Zhu M, Liu X, Jiang L, Xu J, Chen L, Liang J, Li L, Zhou T, Wang Y, Shi H, Yuan Y, Song E"
937a1071,1074
> "Q80XC3-1","24239119","The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration.","Current biology : CB","2013 Dec 2","Palamidessi A, Frittoli E, Ducano N, Offenhauser N, Sigismund S, Kajiho H, Parazzoli D, Oldani A, Gobbi M, Serini G, Di Fiore PP, Scita G, Lanzetti L"
> "Q60651-1","27438766","Activating Receptors for Self-MHC Class I Enhance Effector Functions and Memory Differentiation of NK Cells during Mouse Cytomegalovirus Infection.","Immunity","2016 Jul 19","Nabekura T, Lanier LL"
> "Q60651-1","19247984","DAP10 associates with Ly49 receptors but contributes minimally to their expression and function in vivo.","European journal of immunology","2009 Apr","Tassi I, Le Friec G, Gilfillan S, Takai T, Yokoyama WM, Colonna M"
> "Q60651-1","19109149","Ly49D engagement on T lymphocytes induces TCR-independent activation and CD8 effector functions that control tumor growth.","Journal of immunology (Baltimore, Md. : 1950)","2009 Jan 1","Merck E, Voyle RB, MacDonald HR"
942,943c1079,1082
< "O55143-1","30299255","The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.","eLife","2018 Oct 9","Makarewich CA, Munir AZ, Schiattarella GG, Bezprozvannaya S, Raguimova ON, Cho EE, Vidal AH, Robia SL, Bassel-Duby R, Olson EN"
< "O55143-1","29986885","The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca(2+)-ATPase, is a major determinant of Ca(2+) alternans in intact mouse hearts.","The Journal of biological chemistry","2018 Aug 31","Sun B, Wei J, Zhong X, Guo W, Yao J, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Chen SRW"
---
> "P60762-1","27573846","MRG15 is required for pre-mRNA splicing and spermatogenesis.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 13","Iwamori N, Tominaga K, Sato T, Riehle K, Iwamori T, Ohkawa Y, Coarfa C, Ono E, Matzuk MM"
> "P60762-1","24451372","Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization.","The Journal of biological chemistry","2014 Mar 7","Chen Y, Li J, Dunn S, Xiong S, Chen W, Zhao Y, Chen BB, Mallampalli RK, Zou C"
> "Q9DAM5-1","26316591","Chronic alcohol exposure affects pancreatic acinar mitochondrial thiamin pyrophosphate uptake: studies with mouse 266-6 cell line and primary cells.","American journal of physiology. Gastrointestinal and liver physiology","2015 Nov 1","Srinivasan P, Nabokina S, Said HM"
> "Q9DAM5-1","18280798","The evidence that the DNC (SLC25A19) is not the mitochondrial deoxyribonucleotide carrier.","Mitochondrion","2008 Mar","Kang J, Samuels DC"
944a1084,1086
> "Q8BP71-1","30867288","RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.","Proceedings of the National Academy of Sciences of the United States of America","2019 Mar 26","Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, Gou LT, Zhou Y, Zhang J, Ren S, Chen J, Wang Y, Fu XD"
> "Q9Z2H5-1","19503082","Regulation of AMPA receptor extrasynaptic insertion by 4.1N, phosphorylation and palmitoylation.","Nature neuroscience","2009 Jul","Lin DT, Makino Y, Sharma K, Hayashi T, Neve R, Takamiya K, Huganir RL"
> "Q811P0-1","12809675","A cluster of proton/amino acid transporter genes in the human and mouse genomes.","Genomics","2003 Jul","Boll M, Foltz M, Rubio-Aliaga I, Daniel H"
945a1088,1091
> "Q80XP9-1","26861815","Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke.","Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism","2017 Feb","Zhao H, Nepomuceno R, Gao X, Foley LM, Wang S, Begum G, Zhu W, Pigott VM, Falgoust LM, Kahle KT, Yang SS, Lin SH, Alper SL, Hitchens TK, Hu S, Zhang Z, Sun D"
> "Q80XP9-1","16357011","WNK3, a kinase related to genes mutated in hereditary hypertension with hyperkalaemia, regulates the K+ channel ROMK1 (Kir1.1).","The Journal of physiology","2006 Mar 1","Leng Q, Kahle KT, Rinehart J, MacGregor GG, Wilson FH, Canessa CM, Lifton RP, Hebert SC"
> "Q80XP9-1","16275913","WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.","Proceedings of the National Academy of Sciences of the United States of America","2005 Nov 15","Rinehart J, Kahle KT, de Los Heros P, Vazquez N, Meade P, Wilson FH, Hebert SC, Gimenez I, Gamba G, Lifton RP"
> "Q80XP9-1","16275911","WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.","Proceedings of the National Academy of Sciences of the United States of America","2005 Nov 15","Kahle KT, Rinehart J, de Los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP"
950,953c1096,1103
< "Q9QYN3-1","28867182","Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma.","Biochemical and biophysical research communications","2017 Nov 4","Nimpong JA, Gebregziabher W, Singh UP, Nagarkatti P, Nagarkatti M, Hodge J, Liu C, Fan D, Ai W"
< "Q68FG0-1","30177510","Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains.","Development (Cambridge, England)","2018 Sep 3","Kim J, Choi TI, Park S, Kim MH, Kim CH, Lee S"
< "Q68FG0-1","28814648","ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus.","Open biology","2017 Aug","Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B"
< "Q68FG0-1","23623388","ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity.","American journal of human genetics","2013 May 2","Hirata H, Nanda I, van Riesen A, McMichael G, Hu H, Hambrock M, Papon MA, Fischer U, Marouillat S, Ding C, Alirol S, Bienek M, Preisler-Adams S, Grimme A, Seelow D, Webster R, Haan E, MacLennan A, Stenzel W, Yap TY, Gardner A, Nguyen LS, Shaw M, Lebrun N, Haas SA, Kress W, Haaf T, Schellenberger E, Chelly J, Viot G, Shaffer LG, Rosenfeld JA, Kramer N, Falk R, El-Khechen D, Escobar LF, Hennekam R, Wieacker P, Hubner C, Ropers HH, Gecz J, Schuelke M, Laumonnier F, Kalscheuer VM"
---
> "Q61137-1","11861479","Mice that lack astrotactin have slowed neuronal migration.","Development (Cambridge, England)","2002 Feb","Adams NC, Tomoda T, Cooper M, Dietz G, Hatten ME"
> "Q00993-1","30541554","Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation.","Cell communication and signaling : CCS","2018 Dec 12","Zhou J, Yang A, Wang Y, Chen F, Zhao Z, Davra V, Suzuki-Inoue K, Ozaki Y, Birge RB, Lu Q, Wu Y"
> "Q00993-1","30335822","Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.","PloS one","2018","Waterborg CEJ, Koenders MI, van Lent PLEM, van der Kraan PM, van de Loo FAJ"
> "Q9QYC0-1","29032200","Sez6l2 regulates phosphorylation of ADD and neuritogenesis.","Biochemical and biophysical research communications","2017 Dec 9","Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S"
> "Q9QYC0-1","28982183","NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between alpha-Adducin and Myosin X.","PloS one","2017","Brieno-Enriquez MA, Moak SL, Holloway JK, Cohen PE"
> "Q9QYC0-1","27068466","The Actin-Binding Protein alpha-Adducin Is Required for Maintaining Axon Diameter.","Cell reports","2016 Apr 19","Leite SC, Sampaio P, Sousa VF, Nogueira-Rodrigues J, Pinto-Costa R, Peters LL, Brites P, Sousa MM"
> "Q80TH2-3","26025865","FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy.","International journal of cardiology","2015 Sep 15","Rachmin I, Amsalem E, Golomb E, Beeri R, Gilon D, Fang P, Nechushtan H, Kay G, Guo M, Yiqing PL, Foo RS, Fisher DE, Razin E, Tshori S"
> "Q80TH2-3","26056141","Erbin is a novel substrate of the Sag-betaTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.","The Journal of cell biology","2015 Jun 8","Xie CM, Wei D, Zhao L, Marchetto S, Mei L, Borg JP, Sun Y"
954a1105,1106
> "Q7TPM3-1","25215946","Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17.","Cell death and differentiation","2015 Feb","Mojsa B, Mora S, Bossowski JP, Lassot I, Desagher S"
> "Q7TPM3-1","19358823","TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase.","Biochemical and biophysical research communications","2009 May 29","Urano T, Usui T, Takeda S, Ikeda K, Okada A, Ishida Y, Iwayanagi T, Otomo J, Ouchi Y, Inoue S"
964a1117,1121
> "Q8R3Z5-1","29212769","Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-beta1a subunit (CACNB1).","American journal of physiology. Cell physiology","2018 Mar 1","Perez CF, Eltit JM, Lopez JR, Bodnar D, Dulhunty AF, Aditya S, Casarotto MG"
> "Q99P72-2","30055160","Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury.","Experimental neurology","2018 Nov","Meves JM, Geoffroy CG, Kim ND, Kim JJ, Zheng B"
> "Q99P72-2","30051920","Nogo-A inhibits vascular regeneration in ischemic retinopathy.","Glia","2018 Oct","Joly S, Dejda A, Rodriguez L, Sapieha P, Pernet V"
> "Q99P72-2","30040841","Loss of Nogo-A, encoded by the schizophrenia risk gene Rtn4, reduces mGlu3 expression and causes hyperexcitability in hippocampal CA3 circuits.","PloS one","2018","Berry S, Weinmann O, Fritz AK, Rust R, Wolfer D, Schwab ME, Gerber U, Ster J"
> "Q99P72-2","12225863","Expression of Nogo protein by growing axons in the developing nervous system.","Brain research. Molecular brain research","2002 Aug 15","Tozaki H, Kawasaki T, Takagi Y, Hirata T"
966a1124
> "Q8R3P2-1","16923970","T cells develop normally in the absence of both Deltex1 and Deltex2.","Molecular and cellular biology","2006 Oct","Lehar SM, Bevan MJ"
973,979c1131
< "Q8VHL0-1","27914708","Generation and phenotypic analysis of mice lacking all urea transporters.","Kidney international","2017 Feb","Jiang T, Li Y, Layton AT, Wang W, Sun Y, Li M, Zhou H, Yang B"
< "Q8VHL0-1","27091563","Descending thin limb of the intermediate loop expresses both aquaporin 1 and urea transporter A2 in the mouse kidney.","Histochemistry and cell biology","2016 Jul","Kim WY, Lee HW, Han KH, Nam SA, Choi A, Kim YK, Kim J"
< "Q8VHL0-1","26407594","Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3.","Journal of the American Society of Nephrology : JASN","2016 May","Klein JD, Wang Y, Mistry A, LaRocque LM, Molina PA, Rogers RT, Blount MA, Sands JM"
< "Q8VHL0-1","25298344","Extrarenal phenotypes of the UT-B knockout mouse.","Sub-cellular biochemistry","2014","Yang B, Li X, Guo L, Meng Y, Dong Z, Zhao X"
< "Q8VHL0-1","12965892","Lack of UT-B in vasa recta and red blood cells prevents urea-induced improvement of urinary concentrating ability.","American journal of physiology. Renal physiology","2004 Jan","Bankir L, Chen K, Yang B"
< "Q8VHL0-1","12952854","Expression of urea transporters in potassium-depleted mouse kidney.","American journal of physiology. Renal physiology","2003 Dec","Jung JY, Madsen KM, Han KH, Yang CW, Knepper MA, Sands JM, Kim J"
< "Q8VHL0-1","12133842","Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes.","The Journal of biological chemistry","2002 Sep 27","Yang B, Verkman AS"
---
> "Q8BH43-1","29915352","The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.","Nature communications","2018 Jun 18","Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA"
988a1141,1143
> "Q05BQ1-1","24647940","Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2014 Mar 19","Mishra A, Traut MH, Becker L, Klopstock T, Stein V, Klein R"
> "Q05BQ1-1","18268009","The protein dendrite arborization and synapse maturation 1 (Dasm-1) is dispensable for dendrite arborization.","Molecular and cellular biology","2008 Apr","Mishra A, Knerr B, Paixao S, Kramer ER, Klein R"
> "Q05BQ1-1","15755926","Dasm1: a receptor that shapes neuronal dendrites and turns on silent synapses?","Science's STKE : signal transduction knowledge environment","2005 Mar 8","Falls DL"
990,995c1145
< "Q2Q5T5-1","29581287","Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration.","Proceedings of the National Academy of Sciences of the United States of America","2018 Apr 10","Bi P, McAnally JR, Shelton JM, Sanchez-Ortiz E, Bassel-Duby R, Olson EN"
< "Q2Q5T5-1","28569755","Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development.","Nature communications","2017 Jun 1","Quinn ME, Goh Q, Kurosaka M, Gamage DG, Petrany MJ, Prasad V, Millay DP"
< "Q2Q5T5-1","28569745","The microprotein Minion controls cell fusion and muscle formation.","Nature communications","2017 Jun 1","Zhang Q, Vashisht AA, O'Rourke J, Corbel SY, Moran R, Romero A, Miraglia L, Zhang J, Durrant E, Schmedt C, Sampath SC, Sampath SC"
< "Q2Q5T5-1","28386024","Control of muscle formation by the fusogenic micropeptide myomixer.","Science (New York, N.Y.)","2017 Apr 21","Bi P, Ramirez-Martinez A, Li H, Cannavino J, McAnally JR, Shelton JM, Sanchez-Ortiz E, Bassel-Duby R, Olson EN"
< "Q2Q5T5-1","28637957","Gm7325 is MyoD-dependently expressed in activated muscle satellite cells.","Biomedical research (Tokyo, Japan)","2017","Takei D, Nishi M, Fukada S, Doi M, Okamura H, Uezumi A, Zhang L, Yoshida M, Miyazato M, Ichimura A, Takeshima H"
< "Q2Q5T5-1","16331322","Molecular cloning and functional analysis of ESGP, an embryonic stem cell and germ cell specific protein.","Acta biochimica et biophysica Sinica","2005 Dec","Chen YM, Du ZW, Yao Z"
---
> "P47931-1","20032047","The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice.","Endocrinology","2010 Mar","Kimura F, Sidis Y, Bonomi L, Xia Y, Schneyer A"
998,1001c1148,1149
< "Q5NBU8-1","29132171","Metabolic Endotoxemia-Activated Macrophages Promote Pancreatic beta Cell Death via IFNbeta-Xaf1 Pathway.","Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme","2018 Feb","Tsuruta M, Iwashita M, Shinjo T, Matsunaga H, Yamashita A, Nishimura F"
< "Q5NBU8-1","27097110","XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bbeta-mediated apoptosis.","Oncotarget","2016 Jun 7","Choo Z, Koh RY, Wallis K, Koh TJ, Kuick CH, Sobrado V, Kenchappa RS, Loh AH, Soh SY, Schlisio S, Chang KT, Chen ZX"
< "Q5NBU8-1","18192275","Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation.","The Journal of biological chemistry","2008 Mar 14","Bai Y, Ahmad U, Wang Y, Li JH, Choy JC, Kim RW, Kirkiles-Smith N, Maher SE, Karras JG, Bennett CF, Bothwell AL, Pober JS, Tellides G"
< "Q5NBU8-1","18544999","XIAP-associated factor 1 (XAF1) suppresses angiogenesis in mouse endothelial cells.","Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine","2008","Qiao L, Gu Q, Dai Y, Shen Z, Liu X, Qi R, Ma J, Zou B, Li Z, Lan HY, Wong BC"
---
> "Q9Z2G6-1","28920918","Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus.","The Journal of clinical investigation","2017 Oct 2","Bichet DG, Lussier Y"
> "Q9Z2G6-1","20170518","SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.","BMC developmental biology","2010 Feb 19","Li S, Francisco AB, Munroe RJ, Schimenti JC, Long Q"
1003a1152
> "Q5U4H9-1","28864529","Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation.","Proceedings of the National Academy of Sciences of the United States of America","2017 Sep 19","Gao X, Lee HY, Li W, Platt RJ, Barrasa MI, Ma Q, Elmes RR, Rosenfeld MG, Lodish HF"
1009,1010c1158,1160
< "Q9JKK7-1","24746171","Role of tropomodulin's leucine rich repeat domain in the formation of neurite-like processes.","Biochemistry","2014 Apr 29","Guillaud L, Gray KT, Moroz N, Pantazis C, Pate E, Kostyukova AS"
< "Q9JKK7-1","12799133","Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory.","Molecular and cellular neurosciences","2003 May","Cox PR, Fowler V, Xu B, Sweatt JD, Paylor R, Zoghbi HY"
---
> "Q9QYB8-1","29032200","Sez6l2 regulates phosphorylation of ADD and neuritogenesis.","Biochemical and biophysical research communications","2017 Dec 9","Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S"
> "Q9QYB8-1","27480796","Acute drug-induced spine changes in the nucleus accumbens are dependent on beta-adducin.","Neuropharmacology","2016 Nov","Engmann O, Giralt A, Girault JA"
> "Q9QYB8-1","15728854","Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2005 Feb 23","Rabenstein RL, Addy NA, Caldarone BJ, Asaka Y, Gruenbaum LM, Peters LL, Gilligan DM, Fitzsimonds RM, Picciotto MR"
1017a1168
> "B9EHT4-1","25572395","ClipR-59 interacts with Elmo2 and modulates myoblast fusion.","The Journal of biological chemistry","2015 Mar 6","Sun Y, Ren W, Cote JF, Hinds PW, Hu X, Du K"
1020a1172,1175
> "Q9D8T0-1","30996264","The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration.","Nature communications","2019 Apr 17","Sala D, Cunningham TJ, Stec MJ, Etxaniz U, Nicoletti C, Dall'Agnese A, Puri PL, Duester G, Latella L, Sacco A"
> "Q9D8T0-1","24806753","FAM3A activates PI3K p110alpha/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.","Hepatology (Baltimore, Md.)","2014 May","Wang C, Chi Y, Li J, Miao Y, Li S, Su W, Jia S, Chen Z, Du S, Zhang X, Zhou Y, Wu W, Zhu M, Wang Z, Yang H, Xu G, Wang S, Yang J, Guan Y"
> "Q9JLN6-1","28707394","CD19 regulates ADAM28-mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells.","Journal of cellular and molecular medicine","2017 Dec","Zhang Y, Zhu G, Xiao H, Liu X, Han G, Chen G, Hou C, Shen B, Li Y, Ma N, Wang R"
> "Q9JLN6-1","11724793","The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1.","The Journal of biological chemistry","2002 Feb 1","Bridges LC, Tani PH, Hanson KR, Roberts CM, Judkins MB, Bowditch RD"
1032c1187,1189
< "P97863-1","29965871","A novel long noncoding RNA lnc158 promotes the differentiation of mouse neural precursor cells into oligodendrocytes by targeting nuclear factor-IB.","Neuroreport","2018 Sep 5","Li Y, Guo B, Yang R, Xiao Z, Gao X, Yu J, Li S, Luo Y"
---
> "Q60575-1","28637693","Neuroblast differentiation during development and in neuroblastoma requires KIF1Bbeta-mediated transport of TRKA.","Genes &amp; development","2017 May 15","Fell SM, Li S, Wallis K, Kock A, Surova O, Rraklli V, Hofig CS, Li W, Mittag J, Henriksson MA, Kenchappa RS, Holmberg J, Kogner P, Schlisio S"
> "Q60575-1","27696585","Loss of function of KIF1B impairs oocyte meiotic maturation and early embryonic development in mice.","Molecular reproduction and development","2016 Nov","Kong XW, Wang DH, Zhou CJ, Zhou HX, Liang CG"
> "A2ARM1-1","20826699","Distinct functions of maternal and somatic Pat1 protein paralogs.","RNA (New York, N.Y.)","2010 Nov","Marnef A, Maldonado M, Bugaut A, Balasubramanian S, Kress M, Weil D, Standart N"
1036,1037c1193
< "Q8VDF2-1","31024001","UHRF genes regulate programmed interdigital tissue regression and chondrogenesis in the embryonic limb.","Cell death &amp; disease","2019 Apr 25","Sanchez-Fernandez C, Lorda-Diez CI, Garcia-Porrero JA, Montero JA, Hurle JM"
< "Q8VDF2-1","29968706","Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.","Nature communications","2018 Jul 3","Kim KY, Tanaka Y, Su J, Cakir B, Xiang Y, Patterson B, Ding J, Jung YW, Kim JH, Hysolli E, Lee H, Dajani R, Kim J, Zhong M, Lee JH, Skalnik D, Lim JM, Sullivan GJ, Wang J, Park IH"
---
> "O35737-1","25846207","Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.","The journal of physiological sciences : JPS","2015 Jul","Hamada T, Miyakawa K, Kushige H, Shibata S, Kurachi S"
1043,1046c1199,1200
< "Q6I6G8-1","29260931","Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.","Autophagy","2018","Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H"
< "Q6I6G8-1","27119228","NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.","Oncotarget","2016 May 24","Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, Zhang Y, Lu K, He F, Zhang L"
< "Q6I6G8-1","25555806","NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.","Cellular signalling","2015 Mar","Wei R, Qiu X, Wang S, Li Y, Wang Y, Lu K, Fu Y, Xing G, He F, Zhang L"
< "Q6I6G8-1","15284439","The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Dinudom A, Fotia AB, Lefkowitz RJ, Young JA, Kumar S, Cook DI"
---
> "Q8K4K3-1","30031847","Inverse and correlative relationships between TRIBBLES genes indicate non-redundant functions during normal and malignant hemopoiesis.","Experimental hematology","2018 Oct","Salome M, Hopcroft L, Keeshan K"
> "Q8K4K3-1","17576771","TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta.","The Journal of biological chemistry","2007 Aug 17","Naiki T, Saijou E, Miyaoka Y, Sekine K, Miyajima A"
1056d1209
< "Q8BZM0-1","18303015","BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase.","The Journal of biological chemistry","2008 Apr 25","Rondou P, Haegeman G, Vanhoenacker P, Van Craenenbroeck K"
1058,1060c1211
< "Q9QXS1-1","18541706","Plectin isoform 1b mediates mitochondrion-intermediate filament network linkage and controls organelle shape.","The Journal of cell biology","2008 Jun 16","Winter L, Abrahamsberg C, Wiche G"
< "Q9QXS1-1","17389230","Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.","The Journal of cell biology","2007 Mar 26","Rezniczek GA, Konieczny P, Nikolic B, Reipert S, Schneller D, Abrahamsberg C, Davies KE, Winder SJ, Wiche G"
< "Q9QXS1-1","12542521","Plectin-isoform-specific rescue of hemidesmosomal defects in plectin (-/-) keratinocytes.","The Journal of investigative dermatology","2003 Feb","Andra K, Kornacker I, Jorgl A, Zorer M, Spazierer D, Fuchs P, Fischer I, Wiche G"
---
> "Q9D8K8-1","19656490","Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.","Cell metabolism","2009 Aug","Nilsson R, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kaplan J, Palis J, Paw BH, Mootha VK"
1066,1069d1216
< "Q3ULW8-1","30213852","Parp3 promotes long-range end joining in murine cells.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 2","Layer JV, Cleary JP, Brown AJ, Stevenson KE, Morrow SN, Van Scoyk A, Blasco RB, Karaca E, Meng FL, Frock RL, Tivey T, Kim S, Fuchs H, Chiarle R, Alt FW, Roberts SA, Weinstock DM, Day TA"
< "Q3ULW8-1","26000965","Parp3 negatively regulates immunoglobulin class switch recombination.","PLoS genetics","2015 May","Robert I, Gaudot L, Rogier M, Heyer V, Noll A, Dantzer F, Reina-San-Martin B"
< "Q3ULW8-1","21211721","PARP-3 and APLF function together to accelerate nonhomologous end-joining.","Molecular cell","2011 Jan 7","Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW"
< "Q3ULW8-1","12448766","Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.","Folia biologica","2002","Urbanek P, Paces J, Kralova J, Dvorak M, Paces V"
1071a1219
> "Q9JKC6-1","24312406","Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.","PloS one","2013","Tsioras K, Papastefanaki F, Politis PK, Matsas R, Gaitanou M"
1073c1221,1222
< "P24161-1","28733484","Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 1","Bettini ML, Chou PC, Guy CS, Lee T, Vignali KM, Vignali DAA"
---
> "Q30KP6-1","26987518","Targeted inactivation of the mouse epididymal beta-defensin 41 alters sperm flagellar beat pattern and zona pellucida binding.","Molecular and cellular endocrinology","2016 May 15","Bjorkgren I, Alvarez L, Blank N, Balbach M, Turunen H, Laajala TD, Toivanen J, Krutskikh A, Wahlberg N, Huhtaniemi I, Poutanen M, Wachten D, Sipila P"
> "Q30KP6-1","16023745","Discovery and characterization of new epididymis-specific beta-defensins in mice.","Biochimica et biophysica acta","2005 Jul 25","Jalkanen J, Huhtaniemi I, Poutanen M"
1074a1224,1227
> "Q9Z1G4-1","27512951","Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy.","Cell death &amp; disease","2016 Aug 11","Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, Fu Y, Lin Y, Wen W, Li S, Liu X, Huang H, Vogt A, Liu P, Yin XM, Li M"
> "Q9Z1G4-1","26427489","Modulation of V-ATPase by betaA3/A1-Crystallin in Retinal Pigment Epithelial Cells.","Advances in experimental medicine and biology","2016","Valapala M, Sergeev Y, Wawrousek E, Hose S, Zigler JS Jr, Sinha D"
> "Q9Z1G4-1","24468901","Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/betaA3/A1-crystallin via V-ATPase-MTORC1 signaling.","Autophagy","2014 Mar","Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler JS Jr, Sinha D"
> "Q9Z1G4-1","24165939","The V-ATPase membrane domain is a sensor of granular pH that controls the exocytotic machinery.","The Journal of cell biology","2013 Oct 28","Poea-Guyon S, Ammar MR, Erard M, Amar M, Moreau AW, Fossier P, Gleize V, Vitale N, Morel N"
1075a1229
> "A2AWR3-1","24789282","Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains.","PloS one","2014","Kobayashi M, Ohno T, Ihara K, Murai A, Kumazawa M, Hoshino H, Iwanaga K, Iwai H, Hamana Y, Ito M, Ohno K, Horio F"
1076a1231
> "Q9WTW2-1","26985008","Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2016 Jul","Lisewski U, Koehncke C, Wilck N, Buschmeyer B, Pieske B, Roepke TK"
1090,1092c1245
< "P79621-1","30165873","Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease.","Journal of neuroinflammation","2018 Aug 30","Williams GP, Schonhoff AM, Jurkuvenaite A, Thome AD, Standaert DG, Harms AS"
< "P79621-1","29238041","FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages.","Oncogene","2018 Mar","Yang JB, Zhao ZB, Liu QZ, Hu TD, Long J, Yan K, Lian ZX"
< "P79621-1","28608405","Revisiting the specificity of the MHC class II transactivator CIITA in classical murine dendritic cells in vivo.","European journal of immunology","2017 Aug","Anderson DA 3rd, Grajales-Reyes GE, Satpathy AT, Vasquez Hueichucura CE, Murphy TL, Murphy KM"
---
> "Q810S1-1","23900286","The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.","The EMBO journal","2013 Aug 28","Raffaello A, De Stefani D, Sabbadin D, Teardo E, Merli G, Picard A, Checchetto V, Moro S, Szabo I, Rizzuto R"
1093a1247,1250
> "Q9D8F1-1","25153837","ALKBH4 depletion in mice leads to spermatogenic defects.","PloS one","2014","Nilsen A, Fusser M, Greggains G, Fedorcsak P, Klungland A"
> "Q9D8F1-1","23673617","ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.","Nature communications","2013","Li MM, Nilsen A, Shi Y, Fusser M, Ding YH, Fu Y, Liu B, Niu Y, Wu YS, Huang CM, Olofsson M, Jin KX, Lv Y, Xu XZ, He C, Dong MQ, Rendtlew Danielsen JM, Klungland A, Yang YG"
> "Q925H0-1","30074209","Identification and Function of Acid-sensing Ion Channels in RAW 264.7 Macrophage Cells.","Current medical science","2018 Jun","Ni L, Fang P, Hu ZL, Zhou HY, Chen JG, Wang F, Jin Y"
> "Q925H0-1","27402850","Modulation of Acid-sensing Ion Channel 1a by Intracellular pH and Its Role in Ischemic Stroke.","The Journal of biological chemistry","2016 Aug 26","Li MH, Leng TD, Feng XC, Yang T, Simon RP, Xiong ZG"
1095,1096c1252,1256
< "Q91ZT5-1","25356636","Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge.","PloS one","2014","Ko HK, Guo LW, Su B, Gao L, Gelman IH"
< "Q91ZT5-1","23171661","Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells.","Brain : a journal of neurology","2012 Dec","Horn M, Baumann R, Pereira JA, Sidiropoulos PN, Somandin C, Welzl H, Stendel C, Luhmann T, Wessig C, Toyka KV, Relvas JB, Senderek J, Suter U"
---
> "B2RUP2-1","29141910","Munc13 proteins control regulated exocytosis in mast cells.","The Journal of biological chemistry","2018 Jan 5","Rodarte EM, Ramos MA, Davalos AJ, Moreira DC, Moreno DS, Cardenas EI, Rodarte AI, Petrova Y, Molina S, Rendon LE, Sanchez E, Breaux K, Tortoriello A, Manllo J, Gonzalez EA, Tuvim MJ, Dickey BF, Burns AR, Heidelberger R, Adachi R"
> "Q8BUY8-1","30926797","Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice.","Nature communications","2019 Mar 29","Edfawy M, Guedes JR, Pereira MI, Laranjo M, Carvalho MJ, Gao X, Ferreira PA, Caldeira G, Franco LO, Wang D, Cardoso AL, Feng G, Carvalho AL, Peca J"
> "Q8BUY8-1","26901434","Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.","PloS one","2016","Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H"
> "Q8BUY8-1","25657005","Alternative binding modes identified for growth and differentiation factor-associated serum protein (GASP) family antagonism of myostatin.","The Journal of biological chemistry","2015 Mar 20","Walker RG, Angerman EB, Kattamuri C, Lee YS, Lee SJ, Thompson TB"
> "Q9ER88-1","26306039","Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics.","The Journal of biological chemistry","2015 Oct 9","Xiao L, Xian H, Lee KY, Xiao B, Wang H, Yu F, Shen HM, Liou YC"
1103c1263
< "O88346-1","29931346","TNNT1 nemaline myopathy: natural history and therapeutic frontier.","Human molecular genetics","2018 Sep 15","Fox MD, Carson VJ, Feng HZ, Lawlor MW, Gray JT, Brigatti KW, Jin JP, Strauss KA"
---
> "P56477-1","30902986","Microbial recognition by GEF-H1 controls IKKepsilon mediated activation of IRF5.","Nature communications","2019 Mar 22","Zhao Y, Zagani R, Park SM, Yoshida N, Shah P, Reinecker HC"
1106a1267,1270
> "O70628-1","29505961","Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.","Neurobiology of aging","2018 May","Patel NS, Klett J, Pilarzyk K, Lee DI, Kass D, Menniti FS, Kelly MP"
> "O70628-1","25799991","Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.","Nature","2015 Mar 26","Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA"
> "O70628-1","22596207","The effect of phosphodiesterase inhibitors on the extinction of cocaine-induced conditioned place preference in mice.","Journal of psychopharmacology (Oxford, England)","2012 Oct","Liddie S, Anderson KL, Paz A, Itzhak Y"
> "O70628-1","9624146","Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase.","The Journal of biological chemistry","1998 Jun 19","Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB"
1112a1277
> "Q91V14-1","11701957","Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K(+)-Cl(-) cotransporter (KCC2) defines a new region of conserved homology.","Cytogenetics and cell genetics","2001","Sallinen R, Tornberg J, Putkiranta M, Horelli-Kuitunen N, Airaksinen MS, Wessman M"
1120a1286,1287
> "P97367-1","30190278","Variant PRC1 competes with retinoic acid-related signals to repress Meis2 in the mouse distal forelimb bud.","Development (Cambridge, England)","2018 Oct 11","Yakushiji-Kaminatsui N, Kondo T, Hironaka KI, Sharif J, Endo TA, Nakayama M, Masui O, Koseki Y, Kondo K, Ohara O, Vidal M, Morishita Y, Koseki H"
> "P97367-1","29641989","Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors.","Stem cell reports","2018 Apr 10","Kolb J, Anders-Maurer M, Muller T, Hau AC, Grebbin BM, Kallenborn-Gerhardt W, Behrends C, Schulte D"
1124c1291
< "Q9QXA1-1","29609111","Regulation of anxiety-like behavior and Crhr1 expression in the basolateral amygdala by LMO3.","Psychoneuroendocrinology","2018 Jun","Savarese A, Lasek AW"
---
> "P70175-1","27466188","Altered thalamocortical development in the SAP102 knockout model of intellectual disability.","Human molecular genetics","2016 Sep 15","Crocker-Buque A, Currie SP, Luz LL, Grant SG, Duffy KR, Kind PC, Daw MI"
1127d1293
< "Q8C9A2-3","27108838","Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease.","Scientific reports","2016 Apr 25","Nawaz MS, Vik ES, Ronander ME, Solvoll AM, Blicher P, Bjoras M, Alseth I, Dalhus B"
1136,1142d1301
< "P81069-1","22862946","Targeting tetramer-forming GABPbeta isoforms impairs self-renewal of hematopoietic and leukemic stem cells.","Cell stem cell","2012 Aug 3","Yu S, Jing X, Colgan JD, Zhao DM, Xue HH"
< "P81069-1","18628204","GABPbeta2 is dispensible for normal lymphocyte development but moderately affects B cell responses.","The Journal of biological chemistry","2008 Sep 5","Jing X, Zhao DM, Waldschmidt TJ, Xue HH"
< "Q8K2P7-1","29065407","Hypoxic Stress Upregulates the Expression of Slc38a1 in Brown Adipocytes via Hypoxia-Inducible Factor-1alpha.","Pharmacology","2018","Horie T, Fukasawa K, Iezaki T, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Hinoi E"
< "Q8K2P7-1","28095293","MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.","eLife","2017 Jan 17","Walker LJ, Summers DW, Sasaki Y, Brace EJ, Milbrandt J, DiAntonio A"
< "Q8K2P7-1","27373508","Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.","Mechanisms of development","2016 Aug","Tan BSN, Rathjen PD, Harvey AJ, Gardner DK, Rathjen J"
< "Q8K2P7-1","25957749","Upregulation of Slc38a1 Gene Along with Promotion of Neurosphere Growth and Subsequent Neuronal Specification in Undifferentiated Neural Progenitor Cells Exposed to Theanine.","Neurochemical research","2016 Feb","Takarada T, Ogura M, Nakamichi N, Kakuda T, Nakazato R, Kokubo H, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y"
< "Q8K2P7-1","25673846","Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Feb 11","Jin LW, Horiuchi M, Wulff H, Liu XB, Cortopassi GA, Erickson JD, Maezawa I"
1145a1305,1306
> "Q3U213-1","15722415","Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion.","Proceedings of the National Academy of Sciences of the United States of America","2005 Mar 1","Schimenti JC, Reynolds JL, Planchart A"
> "Q8R4V1-1","15143214","NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.","Proceedings of the National Academy of Sciences of the United States of America","2004 May 25","Ohtsuka M, Arase H, Takeuchi A, Yamasaki S, Shiina R, Suenaga T, Sakurai D, Yokosuka T, Arase N, Iwashima M, Kitamura T, Moriya H, Saito T"
1152a1314,1320
> "Q80TQ2-1","29291351","The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.","Nature medicine","2018 Feb","Ji YX, Huang Z, Yang X, Wang X, Zhao LP, Wang PX, Zhang XJ, Alves-Bezerra M, Cai L, Zhang P, Lu YX, Bai L, Gao MM, Zhao H, Tian S, Wang Y, Huang ZX, Zhu XY, Zhang Y, Gong J, She ZG, Li F, Cohen DE, Li H"
> "Q80TQ2-1","29259980","CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-kappaB Inflammatory Signaling in Mesangial Cells.","BioMed research international","2017","Li Y, Huang W, Xu Y, Zhou L, Liang Y, Gao C, Long Y, Xu Y"
> "Q80TQ2-1","17392286","Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells.","The Journal of biological chemistry","2007 May 25","Jin W, Reiley WR, Lee AJ, Wright A, Wu X, Zhang M, Sun SC"
> "Q80TQ2-1","17053834","Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.","The Journal of clinical investigation","2006 Nov","Zhang J, Stirling B, Temmerman ST, Ma CA, Fuss IJ, Derry JM, Jain A"
> "Q80TQ2-1","16713561","Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.","Cell","2006 May 19","Massoumi R, Chmielarska K, Hennecke K, Pfeifer A, Fassler R"
> "Q80TQ2-1","16501569","Regulation of T cell development by the deubiquitinating enzyme CYLD.","Nature immunology","2006 Apr","Reiley WW, Zhang M, Jin W, Losiewicz M, Donohue KB, Norbury CC, Sun SC"
> "Q80TQ2-1","15226292","NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway.","The Journal of biological chemistry","2004 Aug 27","Jono H, Lim JH, Chen LF, Xu H, Trompouki E, Pan ZK, Mosialos G, Li JD"
1156a1325,1328
> "Q5SSZ7-1","30692207","A ZNRF3-dependent Wnt/beta-catenin signaling gradient is required for adrenal homeostasis.","Genes &amp; development","2019 Feb 1","Basham KJ, Rodriguez S, Turcu AF, Lerario AM, Logan CY, Rysztak MR, Gomez-Sanchez CE, Breault DT, Koo BK, Clevers H, Nusse R, Val P, Hammer GD"
> "Q5SSZ7-1","29735715","ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.","Proceedings of the National Academy of Sciences of the United States of America","2018 May 22","Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes DT, Suzuki M, Burdine RD, Cong F, Koo BK, Clevers H, Stevant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A"
> "Q5SSZ7-1","24349440","Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling.","PloS one","2013","Peng WC, de Lau W, Madoori PK, Forneris F, Granneman JC, Clevers H, Gros P"
> "Q5SSZ7-1","22575959","ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.","Nature","2012 Apr 29","Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F"
1167,1168d1338
< "Q7TQA1-1","28686733","The short mRNA isoform of the immunoglobulin superfamily, member 1 gene encodes an intracellular glycoprotein.","PloS one","2017","Wang Y, Brule E, Silander T, Bak B, Joustra SD, Bernard DJ"
< "Q7TQA1-1","28324000","TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice.","Endocrinology","2017 Apr 1","Turgeon MO, Silander TL, Doycheva D, Liao XH, Rigden M, Ongaro L, Zhou X, Joustra SD, Wit JM, Wade MG, Heuer H, Refetoff S, Bernard DJ"
1170,1173c1340
< "Q80XC3-1","24239119","The GTPase-activating protein RN-tre controls focal adhesion turnover and cell migration.","Current biology : CB","2013 Dec 2","Palamidessi A, Frittoli E, Ducano N, Offenhauser N, Sigismund S, Kajiho H, Parazzoli D, Oldani A, Gobbi M, Serini G, Di Fiore PP, Scita G, Lanzetti L"
< "Q3URY2-1","26933123","GEMC1 is a critical regulator of multiciliated cell differentiation.","The EMBO journal","2016 May 2","Terre B, Piergiovanni G, Segura-Bayona S, Gil-Gomez G, Youssef SA, Attolini CS, Wilsch-Brauninger M, Jung C, Rojas AM, Marjanovic M, Knobel PA, Palenzuela L, Lopez-Rovira T, Forrow S, Huttner WB, Valverde MA, de Bruin A, Costanzo V, Stracker TH"
< "Q3URY2-1","26882546","GemC1 controls multiciliogenesis in the airway epithelium.","EMBO reports","2016 Mar","Arbi M, Pefani DE, Kyrousi C, Lalioti ME, Kalogeropoulou A, Papanastasiou AD, Taraviras S, Lygerou Z"
< "Q3URY2-1","26395491","Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche.","Development (Cambridge, England)","2015 Nov 1","Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Gotz M, Lygerou Z, Taraviras S"
---
> "Q9D140-1","26390218","KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome.","PLoS genetics","2015 Sep","Furio L, Pampalakis G, Michael IP, Nagy A, Sotiropoulou G, Hovnanian A"
1175a1343
> "Q9QXE7-1","14980219","A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.","Cell","2004 Feb 20","Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG"
1190,1194c1358,1363
< "Q8K445-1","26943149","Impairment of Vision in a Mouse Model of Usher Syndrome Type III.","Investigative ophthalmology &amp; visual science","2016 Mar","Tian G, Lee R, Ropelewski P, Imanishi Y"
< "Q8K445-1","19414487","Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation.","Human molecular genetics","2009 Aug 1","Geng R, Geller SF, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Jones SM, Wright CG, Melki S, Imanishi Y, Palczewski K, Alagramam KN, Flannery JG"
< "Q8K445-1","19423712","Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeleton.","The Journal of biological chemistry","2009 Jul 10","Tian G, Zhou Y, Hajkova D, Miyagi M, Dinculescu A, Hauswirth WW, Palczewski K, Geng R, Alagramam KN, Isosomppi J, Sankila EM, Flannery JG, Imanishi Y"
< "Q8K445-1","17493778","Anti-clarin-1 AAV-delivered ribozyme induced apoptosis in the mouse cochlea.","Hearing research","2007 Aug","Aarnisalo AA, Pietola L, Joensuu J, Isosomppi J, Aarnisalo P, Dinculescu A, Lewin AS, Flannery J, Hauswirth WW, Sankila EM, Jero J"
< "Q8K445-1","12080385","USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses.","European journal of human genetics : EJHG","2002 Jun","Adato A, Vreugde S, Joensuu T, Avidan N, Hamalainen R, Belenkiy O, Olender T, Bonne-Tamir B, Ben-Asher E, Espinos C, Millan JM, Lehesjoki AE, Flannery JG, Avraham KB, Pietrokovski S, Sankila EM, Beckmann JS, Lancet D"
---
> "Q3URR7-1","28846095","ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors.","Nature cell biology","2017 Sep","Skamagki M, Correia C, Yeung P, Baslan T, Beck S, Zhang C, Ross CA, Dang L, Liu Z, Giunta S, Chang TP, Wang J, Ananthanarayanan A, Bohndorf M, Bosbach B, Adjaye J, Funabiki H, Kim J, Lowe S, Collins JJ, Lu CW, Li H, Zhao R, Kim K"
> "Q3URR7-1","26592664","Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells.","Biochemical and biophysical research communications","2015 Dec 25","Yamane M, Fujii S, Ohtsuka S, Niwa H"
> "Q3URR7-1","25111779","Pleiotropic functions for transcription factor zscan10.","PloS one","2014","Kraus P, V S, Yu HB, Xing X, Lim SL, Adler T, Pimentel JA, Becker L, Bohla A, Garrett L, Hans W, Holter SM, Janas E, Moreth K, Prehn C, Puk O, Rathkolb B, Rozman J, Adamski J, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Neff F, Ollert M, Stoeger T, Yildrim AO, Eickelberg O, Wolf E, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Lufkin T, Stanton LW"
> "Q3URR7-1","22505416","Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206.","Acta crystallographica. Section F, Structural biology and crystallization communications","2012 Apr 1","Liang Y, Choo SH, Rossbach M, Baburajendran N, Palasingam P, Kolatkar PR"
> "Q3URR7-1","17628018","Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells.","Stem cells (Dayton, Ohio)","2007 Sep","Wang ZX, Kueh JL, Teh CH, Rossbach M, Lim L, Li P, Wong KY, Lufkin T, Robson P, Stanton LW"
> "Q3URR7-1","16971461","Zfp206 regulates ES cell gene expression and differentiation.","Nucleic acids research","2006","Zhang W, Walker E, Tamplin OJ, Rossant J, Stanford WL, Hughes TR"
1201,1202d1369
< "Q60575-1","28637693","Neuroblast differentiation during development and in neuroblastoma requires KIF1Bbeta-mediated transport of TRKA.","Genes &amp; development","2017 May 15","Fell SM, Li S, Wallis K, Kock A, Surova O, Rraklli V, Hofig CS, Li W, Mittag J, Henriksson MA, Kenchappa RS, Holmberg J, Kogner P, Schlisio S"
< "Q60575-1","27696585","Loss of function of KIF1B impairs oocyte meiotic maturation and early embryonic development in mice.","Molecular reproduction and development","2016 Nov","Kong XW, Wang DH, Zhou CJ, Zhou HX, Liang CG"
1213a1381
> "Q8BX57-1","16135750","MONaKA, a novel modulator of the plasma membrane Na,K-ATPase.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2005 Aug 31","Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB"
1216c1384,1392
< "Q3UVR3-1","23141541","The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.","Cell","2012 Nov 9","Goetz SC, Liem KF Jr, Anderson KV"
---
> "A2AGA4-1","21833011","Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing.","The Journal of investigative dermatology","2011 Dec","Cheng TL, Wu YT, Lin HY, Hsu FC, Liu SK, Chang BI, Chen WS, Lai CH, Shi GY, Wu HL"
> "Q9QXL2-1","29158259","Structural analyses of key features in the KANK1.KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex.","The Journal of biological chemistry","2018 Jan 5","Weng Z, Shang Y, Yao D, Zhu J, Zhang R"
> "Q9QXL2-1","22465342","Spatiotemporal expression pattern of KIF21A during normal embryonic development and in congenital fibrosis of the extraocular muscles type 1 (CFEOM1).","Gene expression patterns : GEP","2012 May-Jun","Desai J, Velo MP, Yamada K, Overman LM, Engle EC"
> "Q80WM9-1","29339444","LIGHT-HVEM signaling in keratinocytes controls development of dermatitis.","The Journal of experimental medicine","2018 Feb 5","Herro R, Shui JW, Zahner S, Sidler D, Kawakami Y, Kawakami T, Tamada K, Kronenberg M, Croft M"
> "Q3UHD9-1","28404596","Tumor Necrosis Factor-alpha Promotes Phosphoinositide 3-Kinase Enhancer A and AMP-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle.","Diabetes","2017 Jul","Tse MCL, Herlea-Pana O, Brobst D, Yang X, Wood J, Hu X, Liu Z, Lee CW, Zaw AM, Chow BKC, Ye K, Chan CB"
> "Q3UHD9-1","28096359","alpha-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.","Proceedings of the National Academy of Sciences of the United States of America","2017 Jan 31","Kang SS, Zhang Z, Liu X, Manfredsson FP, He L, Iuvone PM, Cao X, Sun YE, Jin L, Ye K"
> "Q3UHD9-1","24449917","PIKE is essential for oligodendroglia development and CNS myelination.","Proceedings of the National Academy of Sciences of the United States of America","2014 Feb 4","Chan CB, Liu X, Zhao L, Liu G, Lee CW, Feng Y, Ye K"
> "Q3UHD9-1","20068140","Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.","Diabetes","2010 Apr","Chan CB, Liu X, Jung DY, Jun JY, Luo HR, Kim JK, Ye K"
> "Q3UHD9-1","18469807","Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B.","Nature cell biology","2008 Jun","Tang X, Jang SW, Okada M, Chan CB, Feng Y, Liu Y, Luo SW, Hong Y, Rama N, Xiong WC, Mehlen P, Ye K"
1223,1226c1399,1401
< "Q9JMH6-1","30805084","Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia.","Oxidative medicine and cellular longevity","2019","Wall SB, Wood R, Dunigan K, Li Q, Li R, Rogers LK, Tipple TE"
< "Q9JMH6-1","29749372","The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation.","Nature communications","2018 May 10","Muri J, Heer S, Matsushita M, Pohlmeier L, Tortola L, Fuhrer T, Conrad M, Zamboni N, Kisielow J, Kopf M"
< "Q9JMH6-1","28775321","MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation.","Scientific reports","2017 Aug 3","Mercatelli N, Fittipaldi S, De Paola E, Dimauro I, Paronetto MP, Jackson MJ, Caporossi D"
< "Q9JMH6-1","28686716","GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.","PloS one","2017","Han C, Kim MJ, Ding D, Park HJ, White K, Walker L, Gu T, Tanokura M, Yamasoba T, Linser P, Salvi R, Someya S"
---
> "P48794-1","23463525","Digestion products of the PH20 hyaluronidase inhibit remyelination.","Annals of neurology","2013 Feb","Preston M, Gong X, Su W, Matsumoto SG, Banine F, Winkler C, Foster S, Xing R, Struve J, Dean J, Baggenstoss B, Weigel PH, Montine TJ, Back SA, Sherman LS"
> "Q8CBY1-1","24799716","Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.","Proceedings of the National Academy of Sciences of the United States of America","2014 May 20","Chen Z, Holland W, Shelton JM, Ali A, Zhan X, Won S, Tomisato W, Liu C, Li X, Moresco EM, Beutler B"
> "Q8CBY1-1","16221671","Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.","The Journal of biological chemistry","2005 Dec 30","Baez MV, Boccaccio GL"
1234a1410
> "Q62252-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
1240,1250c1416,1420
< "P28574-1","30403691","DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.","PloS one","2018","Tatsumi D, Hayashi Y, Endo M, Kobayashi H, Yoshioka T, Kiso K, Kanno S, Nakai Y, Maeda I, Mochizuki K, Tachibana M, Koseki H, Okuda A, Yasui A, Kono T, Matsui Y"
< "P28574-1","28220481","Does MAX open up a new avenue for meiotic research?","Development, growth &amp; differentiation","2017 Feb","Suzuki A, Hirasaki M, Okuda A"
< "P28574-1","27025988","Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells.","Nature communications","2016 Mar 30","Suzuki A, Hirasaki M, Hishida T, Wu J, Okamura D, Ueda A, Nishimoto M, Nakachi Y, Mizuno Y, Okazaki Y, Matsui Y, Izpisua Belmonte JC, Okuda A"
< "O88508-1","12138111","A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.","The Journal of biological chemistry","2002 Oct 11","Chen T, Ueda Y, Xie S, Li E"
< "Q80XE1-2","29118104","Conditional Deletion of Ric-8b in Olfactory Sensory Neurons Leads to Olfactory Impairment.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Dec 13","Machado CF, Nagai MH, Lyra CS, Reis-Silva TM, Xavier AM, Glezer I, Felicio LF, Malnic B"
< "Q80XE1-2","26062014","Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis.","PloS one","2015","Saare M, Lulla S, Tonissoo T, Meier R, Kask K, Ruisu K, Karis A, Salumets A, Pooga M"
< "Q80XE1-2","24585571","A functional N-terminal domain in C/EBPbeta-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts.","Journal of cellular physiology","2014 Oct","Aguilar R, Grandy R, Meza D, Sepulveda H, Pihan P, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M"
< "Q80XE1-2","24134321","Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric-8B in Gs suppression by Gq signal.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2013 Dec","Jenie RI, Nishimura M, Fujino M, Nakaya M, Mizuno N, Tago K, Kurose H, Itoh H"
< "Q80XE1-2","20133939","Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.","The Journal of biological chemistry","2010 Apr 9","Nagai Y, Nishimura A, Tago K, Mizuno N, Itoh H"
< "Q80XE1-2","18462949","Ric-8B interacts with G alpha olf and G gamma 13 and co-localizes with G alpha olf, G beta 1 and G gamma 13 in the cilia of olfactory sensory neurons.","Molecular and cellular neurosciences","2008 Jul","Kerr DS, Von Dannecker LE, Davalos M, Michaloski JS, Malnic B"
< "Q80XE1-2","16754875","Ric-8B promotes functional expression of odorant receptors.","Proceedings of the National Academy of Sciences of the United States of America","2006 Jun 13","Von Dannecker LE, Mercadante AF, Malnic B"
---
> "P30875-1","30261745","The expression of somatostatin receptor 2 decreases during cyst growth in mice with polycystic kidney disease.","Experimental biology and medicine (Maywood, N.J.)","2018 Sep","Lin C, Happe H, Veraar K, Scharpfenecker M, Peters DJ"
> "P30875-1","29409919","sst2-receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageing.","Progress in neuro-psychopharmacology &amp; biological psychiatry","2018 Aug 30","Prevot TD, Viollet C, Epelbaum J, Dominguez G, Beracochea D, Guillou JL"
> "P30875-1","27986975","Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality.","Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","2017 Jul","Prevot TD, Gastambide F, Viollet C, Henkous N, Martel G, Epelbaum J, Beracochea D, Guillou JL"
> "P30875-1","25683115","Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.","Gastroenterology","2015 Jun","Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F, Delisle MB, Poupot M, Dufresne M, Shimaoka T, Yonehara S, Mathonnet M, Pyronnet S, Bousquet C"
> "P16305-1","29673739","Association of serotonin and GABA pathway gene polymorphisms with alcohol dependence: A preliminary study.","Asian journal of psychiatry","2019 Jan","Sahni S, Tickoo M, Gupta R, Vaswani M, Ambekar A, Grover T, Sharma A"
1254a1425
> "P37040-1","27863990","Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.","Free radical biology &amp; medicine","2017 Jan","Rezende F, Prior KK, Lowe O, Wittig I, Strecker V, Moll F, Helfinger V, Schnutgen F, Kurrle N, Wempe F, Walter M, Zukunft S, Luck B, Fleming I, Weissmann N, Brandes RP, Schroder K"
1257a1429
> "Q99M96-1","15485929","Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.","Molecular and cellular biology","2004 Nov","Pal S, Vishwanath SN, Erdjument-Bromage H, Tempst P, Sif S"
1266a1439,1442
> "P31809-1","31083261","CEACAM-1 promotes myocardial injury following coxsackievirus infection by regulating the coxsackievirus-adenovirus receptor.","Medicine","2019 May","Zhang Z, Long C, Li X, Xie Q, Song M, Zhang Y"
> "P31809-1","29967450","CEACAM1 promotes CD8(+) T cell responses and improves control of a chronic viral infection.","Nature communications","2018 Jul 2","Khairnar V, Duhan V, Patil AM, Zhou F, Bhat H, Thoens C, Sharma P, Adomati T, Friendrich SK, Bezgovsek J, Dreesen JD, Wennemuth G, Westendorf AM, Zelinskyy G, Dittmer U, Hardt C, Timm J, Gothert JR, Lang PA, Singer BB, Lang KS"
> "Q3U0P1-1","28240985","A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.","eLife","2017 Feb 27","Luijsterburg MS, Typas D, Caron MC, Wiegant WW, van den Heuvel D, Boonen RA, Couturier AM, Mullenders LH, Masson JY, van Attikum H"
> "Q3U0P1-1","20484223","Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.","Human molecular genetics","2010 Aug 1","Rantakari P, Nikkila J, Jokela H, Ola R, Pylkas K, Lagerbohm H, Sainio K, Poutanen M, Winqvist R"
1272,1279d1447
< "Q99NE5-1","29891949","Postsynaptic RIM1 modulates synaptic function by facilitating membrane delivery of recycling NMDARs in hippocampal neurons.","Nature communications","2018 Jun 11","Wang J, Lv X, Wu Y, Xu T, Jiao M, Yang R, Li X, Chen M, Yan Y, Chen C, Dong W, Yang W, Zhuo M, Chen T, Luo J, Qiu S"
< "Q99NE5-1","11797010","RIM1alpha is required for presynaptic long-term potentiation.","Nature","2002 Jan 17","Castillo PE, Schoch S, Schmitz F, Sudhof TC, Malenka RC"
< "Q99NE5-1","11797009","RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone.","Nature","2002 Jan 17","Schoch S, Castillo PE, Jo T, Mukherjee K, Geppert M, Wang Y, Schmitz F, Malenka RC, Sudhof TC"
< "Q6HA09-1","28911209","Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida.","Molecular human reproduction","2017 Sep 1","Korschgen H, Kuske M, Karmilin K, Yiallouros I, Balbach M, Floehr J, Wachten D, Jahnen-Dechent W, Stocker W"
< "Q6HA09-1","28114310","A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice.","PLoS genetics","2017 Jan","Xiong B, Zhao Y, Beall S, Sadusky AB, Dean J"
< "Q6HA09-1","22472438","Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy.","The Journal of cell biology","2012 Apr 2","Burkart AD, Xiong B, Baibakov B, Jimenez-Movilla M, Dean J"
< "Q6HA09-1","22206759","Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization.","Developmental biology","2012 Mar 1","Sachdev M, Mandal A, Mulders S, Digilio LC, Panneerdoss S, Suryavathi V, Pires E, Klotz KL, Hermens L, Herrero MB, Flickinger CJ, van Duin M, Herr JC"
< "Q6HA09-1","22275110","Astacin-like metallo-endopeptidase is dynamically expressed in embryonic stem cells and embryonic epithelium during morphogenesis.","Developmental dynamics : an official publication of the American Association of Anatomists","2012 Mar","Acloque H, Lavial F, Pain B"
1286d1453
< "Q8C181-1","29735517","Opposing roles of miR-294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cells.","EMBO reports","2018 Jun","Wu DR, Gu KL, Yu JC, Fu X, Wang XW, Guo WT, Liao LQ, Zhu H, Zhang XS, Hui J, Wang Y"
1291d1457
< "Q5F2L2-1","23986452","The Lewis X-related alpha1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations.","The Journal of biological chemistry","2013 Oct 4","Kumar A, Torii T, Ishino Y, Muraoka D, Yoshimura T, Togayachi A, Narimatsu H, Ikenaka K, Hitoshi S"
1313a1480
> "Q9D7V1-1","18641339","Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells.","Journal of immunology (Baltimore, Md. : 1950)","2008 Aug 1","Lapinski PE, Oliver JA, Kamen LA, Hughes ED, Saunders TL, King PD"
1325,1326d1491
< "O08791-1","29869132","The caudo-ventral pallium is a novel pallial domain expressing Gdf10 and generating Ebf3-positive neurons of the medial amygdala.","Brain structure &amp; function","2018 Sep","Ruiz-Reig N, Andres B, Lamonerie T, Theil T, Fairen A, Studer M"
< "O08791-1","29563184","Stem cell niche-specific Ebf3 maintains the bone marrow cavity.","Genes &amp; development","2018 Mar 1","Seike M, Omatsu Y, Watanabe H, Kondoh G, Nagasawa T"
1332a1498,1499
> "Q9QY48-1","21390259","DNase 2 is the main DNA-degrading enzyme of the stratum corneum.","PloS one","2011 Mar 1","Fischer H, Scherz J, Szabo S, Mildner M, Benarafa C, Torriglia A, Tschachler E, Eckhart L"
> "Q9QY48-1","11700027","Isolation and characterization of the DLAD/Dlad genes, which lie head-to-head with the genes for urate oxidase.","Biochemical and biophysical research communications","2001 Nov 16","Shiokawa D, Tanuma SI"
1334c1501
< "Q9D824-1","16690743","Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.","Proceedings of the National Academy of Sciences of the United States of America","2006 May 23","Stover EH, Chen J, Folens C, Lee BH, Mentens N, Marynen P, Williams IR, Gilliland DG, Cools J"
---
> "P97379-1","22357953","Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.","Journal of cell science","2012 May 15","Bikkavilli RK, Malbon CC"
1337,1338c1504,1509
< "P61793-1","30622227","HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells.","Molecules and cells","2019 Feb 28","Kim NH, Sadra A, Park HY, Oh SM, Chun J, Yoon JK, Huh SO"
< "P61793-1","29051083","Lysophosphatidic acid propagates post-injury Schwann cell dedifferentiation through LPA1 signaling.","Neuroscience letters","2018 Jan 1","Szepanowski F, Szepanowski LP, Mausberg AK, Kleinschnitz C, Kieseier BC, Stettner M"
---
> "Q8BGD6-1","29053970","mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.","Cell","2017 Oct 19","Wyant GA, Abu-Remaileh M, Wolfson RL, Chen WW, Freinkman E, Danai LV, Vander Heiden MG, Sabatini DM"
> "Q91ZT5-1","25356636","Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge.","PloS one","2014","Ko HK, Guo LW, Su B, Gao L, Gelman IH"
> "Q91ZT5-1","23171661","Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells.","Brain : a journal of neurology","2012 Dec","Horn M, Baumann R, Pereira JA, Sidiropoulos PN, Somandin C, Welzl H, Stendel C, Luhmann T, Wessig C, Toyka KV, Relvas JB, Senderek J, Suter U"
> "E9PYH6-1","29968706","Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.","Nature communications","2018 Jul 3","Kim KY, Tanaka Y, Su J, Cakir B, Xiang Y, Patterson B, Ding J, Jung YW, Kim JH, Hysolli E, Lee H, Dajani R, Kim J, Zhong M, Lee JH, Skalnik D, Lim JM, Sullivan GJ, Wang J, Park IH"
> "P97434-1","16243315","Inhibition of RhoA-mediated SRF activation by p116Rip.","FEBS letters","2005 Nov 7","Mulder J, Ariaens A, van Horck FP, Moolenaar WH"
> "P97434-1","12732640","p116Rip is a novel filamentous actin-binding protein.","The Journal of biological chemistry","2003 Jul 18","Mulder J, Poland M, Gebbink MF, Calafat J, Moolenaar WH, Kranenburg O"
1343a1515
> "Q61464-1","21602272","Regulation of adipocyte differentiation by the zinc finger protein ZNF638.","The Journal of biological chemistry","2011 Jul 29","Meruvu S, Hugendubler L, Mueller E"
1359,1364c1531,1534
< "P97819-1","27789386","Role of prefrontal cortical calcium-independent phospholipase A2 in antinociceptive effect of the norepinephrine reuptake inhibitor antidepresssant maprotiline.","Neuroscience","2017 Jan 6","Chew WS, Shalini SM, Torta F, Wenk MR, Stohler C, Yeo JF, Herr DR, Ong WY"
< "P97819-1","15024020","Small interfering RNA knockdown of calcium-independent phospholipases A2 beta or gamma inhibits the hormone-induced differentiation of 3T3-L1 preadipocytes.","The Journal of biological chemistry","2004 May 21","Su X, Mancuso DJ, Bickel PE, Jenkins CM, Gross RW"
< "P97819-1","12167650","Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression.","The Journal of biological chemistry","2002 Oct 11","Maggi LB Jr, Moran JM, Scarim AL, Ford DA, Yoon JW, McHowat J, Buller RM, Corbett JA"
< "Q8R5L3-1","20961651","The TGF-beta signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development.","Immunobiology","2011 Mar","Messler S, Kropp S, Episkopou V, Felici A, Wurthner J, Lemke R, Jerabek-Willemsen M, Willecke R, Scheu S, Pfeffer K, Wurthner JU"
< "Q8R5L3-1","20363736","Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence.","The Journal of biological chemistry","2010 May 28","Peralta ER, Martin BC, Edinger AL"
< "Q8R5L3-1","15110766","Spatio-temporal organization of Vam6P and SNAP on mouse spermatozoa and their involvement in sperm-zona pellucida interactions.","Biochemical and biophysical research communications","2004 May 21","Brahmaraju M, Shoeb M, Laloraya M, Kumar PG"
---
> "Q66JX5-1","29982567","Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy.","Human molecular genetics","2018 Oct 1","Cabaud O, Roubin R, Comte A, Bascunana V, Serge A, Sedjai F, Birnbaum D, Rosnet O, Acquaviva C"
> "Q66JX5-1","12969958","FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice.","Blood","2004 Jan 1","Guasch G, Delaval B, Arnoulet C, Xie MJ, Xerri L, Sainty D, Birnbaum D, Pebusque MJ"
> "Q8R4V2-1","27891578","Dual specificity phosphatase 15 regulates Erk activation in Schwann cells.","Journal of neurochemistry","2017 Feb","Rodriguez-Molina JF, Lopez-Anido C, Ma KH, Zhang C, Olson T, Muth KN, Weider M, Svaren J"
> "Q8R4V2-1","15138252","VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.","The Journal of biological chemistry","2004 Jul 30","Alonso A, Narisawa S, Bogetz J, Tautz L, Hadzic R, Huynh H, Williams S, Gjorloff-Wingren A, Bremer MC, Holsinger LJ, Millan JL, Mustelin T"
1373a1544,1546
> "Q923X4-1","29274570","Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria.","Redox biology","2018 May","Chalker J, Gardiner D, Kuksal N, Mailloux RJ"
> "Q923X4-1","29101900","Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies.","Redox biology","2018 Apr","Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME"
> "Q923X4-1","28618115","Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia.","Glia","2017 Sep","Lepka K, Volbracht K, Bill E, Schneider R, Rios N, Hildebrandt T, Ingwersen J, Prozorovski T, Lillig CH, van Horssen J, Steinman L, Hartung HP, Radi R, Holmgren A, Aktas O, Berndt C"
1387a1561,1564
> "Q69ZU8-1","25218921","Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.","Developmental biology","2014 Nov 1","Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P"
> "Q69ZU8-1","20827749","Expression and proliferation-promoting role of Diversin in the neuronally committed precursor cells migrating in the adult mouse brain.","Stem cells (Dayton, Ohio)","2010 Nov","Ikeda M, Hirota Y, Sakaguchi M, Yamada O, Kida YS, Ogura T, Otsuka T, Okano H, Sawamoto K"
> "Q69ZU8-1","19789178","Centrosomal localization of Diversin and its relevance to Wnt signaling.","Journal of cell science","2009 Oct 15","Itoh K, Jenny A, Mlodzik M, Sokol SY"
> "Q69ZU8-1","12203740","Expression of the ankyrin repeat domain 6 gene (Ankrd6) during mouse brain development.","Developmental dynamics : an official publication of the American Association of Anatomists","2002 Aug","Tissir F, Bar I, Goffinet AM, Lambert De Rouvroit C"
1390,1393d1566
< "Q8BYH8-1","29665362","Chd9 mediates highly loosened chromatin structure in growing mouse oocytes.","Biochemical and biophysical research communications","2018 Jun 7","Ooga M, Funaya S, Hashioka Y, Fujii W, Naito K, Suzuki MG, Aoki F"
< "Q8BYH8-1","25689118","New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes.","Journal of cellular physiology","2015 Sep","Salomon-Kent R, Marom R, John S, Dundr M, Schiltz LR, Gutierrez J, Workman J, Benayahu D, Hager GL"
< "Q8BYH8-1","16523501","Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors.","Journal of cellular physiology","2006 Jun","Marom R, Shur I, Hager GL, Benayahu D"
< "Q8BYH8-1","16419031","In vivo association of CReMM/CHD9 with promoters in osteogenic cells.","Journal of cellular physiology","2006 May","Shur I, Socher R, Benayahu D"
1401a1575,1577
> "Q8CGN4-1","30902969","Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis.","Nature communications","2019 Mar 22","Kelly MJ, So J, Rogers AJ, Gregory G, Li J, Zethoven M, Gearhart MD, Bardwell VJ, Johnstone RW, Vervoort SJ, Kats LM"
> "Q8CGN4-1","28827447","Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.","The Journal of experimental medicine","2017 Oct 2","Tanaka T, Nakajima-Takagi Y, Aoyama K, Tara S, Oshima M, Saraya A, Koide S, Si S, Manabe I, Sanada M, Nakayama M, Masuko M, Sone H, Koseki H, Iwama A"
> "Q8CGN4-1","28262675","Genomic characterisation of Emu-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.","Nature communications","2017 Mar 6","Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW"
1404a1581,1582
> "P42227-1","30996264","The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration.","Nature communications","2019 Apr 17","Sala D, Cunningham TJ, Stec MJ, Etxaniz U, Nicoletti C, Dall'Agnese A, Puri PL, Duester G, Latella L, Sacco A"
> "Q9ESE1-1","28893864","The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.","EMBO reports","2017 Nov","Vogl C, Butola T, Haag N, Hausrat TJ, Leitner MG, Moutschen M, Lefebvre PP, Speckmann C, Garrett L, Becker L, Fuchs H, Hrabe de Angelis M, Nietzsche S, Kessels MM, Oliver D, Kneussel M, Kilimann MW, Strenzke N"
1412a1591,1594
> "Q3U8K7-1","27920088","SUV4-20 activity in the preimplantation mouse embryo controls timely replication.","Genes &amp; development","2016 Nov 15","Eid A, Rodriguez-Terrones D, Burton A, Torres-Padilla ME"
> "Q3U8K7-1","26669898","Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation.","Cell stem cell","2016 Feb 4","Boonsanay V, Zhang T, Georgieva A, Kostin S, Qi H, Yuan X, Zhou Y, Braun T"
> "Q3U8K7-1","23720823","FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.","Journal of molecular cell biology","2013 Oct","Neguembor MV, Xynos A, Onorati MC, Caccia R, Bortolanza S, Godio C, Pistoni M, Corona DF, Schotta G, Gabellini D"
> "Q3U8K7-1","17846168","Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.","The Journal of cell biology","2007 Sep 10","Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA"
1416,1421d1597
< "P63058-1","29753845","Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling.","Toxicology letters","2018 Sep 15","Yu Z, Han Y, Shen R, Huang K, Xu YY, Wang QN, Zhou SS, Xu DX, Tao FB"
< "P63058-1","29648626","Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function.","Endocrinology","2018 May 1","van der Spek AH, Surovtseva OV, Jim KK, van Oudenaren A, Brouwer MC, Vandenbroucke-Grauls CMJE, Leenen PJM, van de Beek D, Hernandez A, Fliers E, Boelen A"
< "Q8VHX6-1","26929074","HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles.","Journal of cell science","2016 Apr 15","Juo LY, Liao WC, Shih YL, Yang BY, Liu AB, Yan YT"
< "Q8CHB8-1","28173158","Mutations in the polyglutamylase gene TTLL5, expressed in photoreceptor cells and spermatozoa, are associated with cone-rod degeneration and reduced male fertility.","Human molecular genetics","2016 Oct 15","Bedoni N, Haer-Wigman L, Vaclavik V, Tran VH, Farinelli P, Balzano S, Royer-Bertrand B, El-Asrag ME, Bonny O, Ikonomidis C, Litzistorf Y, Nikopoulos K, Yioti GG, Stefaniotou MI, McKibbin M, Booth AP, Ellingford JM, Black GC, Toomes C, Inglehearn CF, Hoyng CB, Bax N, Klaver CC, Thiadens AA, Murisier F, Schorderet DF, Ali M, Cremers FP, Andreasson S, Munier FL, Rivolta C"
< "Q8CHB8-1","27162334","Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.","Proceedings of the National Academy of Sciences of the United States of America","2016 May 24","Sun X, Park JH, Gumerson J, Wu Z, Swaroop A, Qian H, Roll-Mecak A, Li T"
< "Q8CHB8-1","23558686","Disruption of Ttll5/stamp gene (tubulin tyrosine ligase-like protein 5/SRC-1 and TIF2-associated modulatory protein gene) in male mice causes sperm malformation and infertility.","The Journal of biological chemistry","2013 May 24","Lee GS, He Y, Dougherty EJ, Jimenez-Movilla M, Avella M, Grullon S, Sharlin DS, Guo C, Blackford JA Jr, Awasthi S, Zhang Z, Armstrong SP, London EC, Chen W, Dean J, Simons SS Jr"
1422a1599,1600
> "Q8BHN3-1","18648322","Temporal neuropathologic and behavioral phenotype of 6neo/6neo Pompe disease mice.","Journal of neuropathology and experimental neurology","2008 Aug","Sidman RL, Taksir T, Fidler J, Zhao M, Dodge JC, Passini MA, Raben N, Thurberg BL, Cheng SH, Shihabuddin LS"
> "Q61823-1","30760284","SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination.","Journal of experimental &amp; clinical cancer research : CR","2019 Feb 13","Li C, Du L, Ren Y, Liu X, Jiao Q, Cui D, Wen M, Wang C, Wei G, Wang Y, Ji A, Wang Q"
1425a1604,1605
> "Q8C0Y1-1","30808659","TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth.","Genes &amp; development","2019 Apr 1","Shah A, Melhuish TA, Fox TE, Frierson HF Jr, Wotton D"
> "Q8C0Y1-1","27956704","Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.","Molecular and cellular biology","2017 Mar 1","Anderson AE, Taniguchi K, Hao Y, Melhuish TA, Shah A, Turner SD, Sutherland AE, Wotton D"
1427,1429d1606
< "Q8C863-1","29925997","The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR.","Nature immunology","2018 Jul","Aki D, Li H, Zhang W, Zheng M, Elly C, Lee JH, Zou W, Liu YC"
< "Q8C863-1","29515120","Itch/beta-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.","Nature communications","2018 Mar 7","Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazza D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L"
< "Q8C863-1","28747490","Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.","EMBO reports","2017 Sep","Zhu K, Shan Z, Chen X, Cai Y, Cui L, Yao W, Wang Z, Shi P, Tian C, Lou J, Xie Y, Wen W"
1431,1433c1608
< "Q6PCM1-1","29674659","Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch.","Nature communications","2018 Apr 19","Abe Y, Fujiwara Y, Takahashi H, Matsumura Y, Sawada T, Jiang S, Nakaki R, Uchida A, Nagao N, Naito M, Kajimura S, Kimura H, Osborne TF, Aburatani H, Kodama T, Inagaki T, Sakai J"
< "Q6PCM1-1","29526734","Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.","Stem cell reports","2018 Apr 10","Kuroki S, Nakai Y, Maeda R, Okashita N, Akiyoshi M, Yamaguchi Y, Kitano S, Miyachi H, Nakato R, Ichiyanagi K, Shirahige K, Kimura H, Shinkai Y, Tachibana M"
< "Q6PCM1-1","16619273","Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71.","Journal of cellular biochemistry","2006 Sep 1","Knebel J, De Haro L, Janknecht R"
---
> "P68404-1","29744369","Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice.","Journal of diabetes research","2018","Zheng J, Wang Y, Han S, Luo Y, Sun X, Zhu N, Zhao L, Li J"
1439,1447d1613
< "Q8BX10-1","29770487","Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury.","Journal of pineal research","2018 Oct","Zhou H, Li D, Zhu P, Ma Q, Toan S, Wang J, Hu S, Chen Y, Zhang Y"
< "Q8BX10-1","29524517","Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control.","Life sciences","2018 May 1","Hong JM, Lee SM"
< "Q8BX10-1","29438981","Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling.","The Journal of cell biology","2018 Apr 2","Bernkopf DB, Jalal K, Bruckner M, Knaup KX, Gentzel M, Schambony A, Behrens J"
< "Q8BX10-1","26381214","Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.","Nature communications","2015 Sep 18","Kang YJ, Bang BR, Han KH, Hong L, Shim EJ, Ma J, Lerner RA, Otsuka M"
< "Q8BX10-1","25222142","Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.","Nature communications","2014 Sep 15","Lu W, Karuppagounder SS, Springer DA, Allen MD, Zheng L, Chao B, Zhang Y, Dawson VL, Dawson TM, Lenardo M"
< "Q8BX10-1","25012655","A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5.","The Journal of biological chemistry","2014 Sep 5","Wilkins JM, McConnell C, Tipton PA, Hannink M"
< "Q8BX10-1","22265414","The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways.","Cell","2012 Jan 20","Wang Z, Jiang H, Chen S, Du F, Wang X"
< "Q5DTM8-1","28453857","Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination.","Nucleic acids research","2017 Jul 7","Lee BK, Lee J, Shen W, Rhee C, Chung H, Kim J"
< "Q5DTM8-1","20738173","Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells.","Radiation research","2010 Nov","Chernikova SB, Dorth JA, Razorenova OV, Game JC, Brown JM"
1452,1453d1617
< "Q8K1E0-1","28000760","Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo.","Scientific reports","2016 Dec 21","Rivera-Monroy J, Musiol L, Unthan-Fechner K, Farkas A, Clancy A, Coy-Vergara J, Weill U, Gockel S, Lin SY, Corey DP, Kohl T, Strobel P, Schuldiner M, Schwappach B, Vilardi F"
< "Q8K1E0-1","18836075","Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.","Proceedings of the National Academy of Sciences of the United States of America","2008 Oct 14","Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S"
1458a1623,1624
> "Q99KW3-3","28209736","Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Mar 29","Kazmierczak M, Kazmierczak P, Peng AW, Harris SL, Shah P, Puel JL, Lenoir M, Franco SJ, Schwander M"
> "Q99KW3-3","23789641","R1 motif is the major actin-binding domain of TRIOBP-4.","Biochemistry","2013 Aug 6","Bao J, Bielski E, Bachhawat A, Taha D, Gunther LK, Thirumurugan K, Kitajiri S, Sakamoto T"
1464a1631
> "O35903-1","26921718","Thymus-expressed chemokine enhances Porphyromonas gingivalis LPS-induced osteoclast formation via NFATc1 activation.","Archives of oral biology","2016 Jun","Usui M, Okamatsu Y, Sato T, Hanatani T, Moritani Y, Sano K, Yamamoto M, Nakashima K"
1469a1637,1638
> "A2AQ92-1","28982074","Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.","Redox biology","2018 Apr","Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL"
> "Q8BWL5-1","22372950","Rbms3, an RNA-binding protein, mediates the expression of Ptf1a by binding to its 3'UTR during mouse pancreas development.","DNA and cell biology","2012 Jul","Lu CK, Lai YC, Chen HR, Chiang MK"
1477,1480d1645
< "Q9CPV0-1","28954202","Ciliopathy Protein Tmem107 Plays Multiple Roles in Craniofacial Development.","Journal of dental research","2018 Jan","Cela P, Hampl M, Shylo NA, Christopher KJ, Kavkova M, Landova M, Zikmund T, Weatherbee SD, Kaiser J, Buchtova M"
< "Q9CPV0-1","26518474","TMEM107 Is a Critical Regulator of Ciliary Protein Composition and Is Mutated in Orofaciodigital Syndrome.","Human mutation","2016 Feb","Shylo NA, Christopher KJ, Iglesias A, Daluiski A, Weatherbee SD"
< "Q9CPV0-1","26595381","TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.","Nature cell biology","2016 Jan","Lambacher NJ, Bruel AL, van Dam TJ, Szymanska K, Slaats GG, Kuhns S, McManus GJ, Kennedy JE, Gaff K, Wu KM, van der Lee R, Burglen L, Doummar D, Riviere JB, Faivre L, Attie-Bitach T, Saunier S, Curd A, Peckham M, Giles RH, Johnson CA, Huynen MA, Thauvin-Robinet C, Blacque OE"
< "Q9CPV0-1","22698544","Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.","Developmental biology","2012 Aug 15","Christopher KJ, Wang B, Kong Y, Weatherbee SD"
1482a1648
> "Q6P9R2-1","30563844","Regulation of erythrocyte Na(+)/K(+)/2Cl(-) cotransport by an oxygen-switched kinase cascade.","The Journal of biological chemistry","2019 Feb 15","Zheng S, Krump NA, McKenna MM, Li YH, Hannemann A, Garrett LJ, Gibson JS, Bodine DM, Low PS"
1485a1652
> "Q08857-1","30290792","Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure.","BMC genomics","2018 Oct 5","Santander N, Lizama C, Murgas L, Contreras S, Martin AJM, Molina P, Quiroz A, Rivera K, Salas-Perez F, Godoy A, Rigotti A, Busso D"
1487a1655,1659
> "Q9JMK2-1","29784789","CK1delta/epsilon protein kinase primes the PER2 circadian phosphoswitch.","Proceedings of the National Academy of Sciences of the United States of America","2018 Jun 5","Narasimamurthy R, Hunt SR, Lu Y, Fustin JM, Okamura H, Partch CL, Forger DB, Kim JK, Virshup DM"
> "Q9JMK2-1","29463694","Desynchrony between brain and peripheral clocks caused by CK1delta/epsilon disruption in GABA neurons does not lead to adverse metabolic outcomes.","Proceedings of the National Academy of Sciences of the United States of America","2018 Mar 6","van der Vinne V, Swoap SJ, Vajtay TJ, Weaver DR"
> "Q9JMK2-1","28963394","Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.","The EMBO journal","2017 Oct 16","Morgenstern Y, Das Adhikari U, Ayyash M, Elyada E, Toth B, Moor A, Itzkovitz S, Ben-Neriah Y"
> "P58681-1","14976262","Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.","Science (New York, N.Y.)","2004 Mar 5","Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S"
> "P58681-1","14976261","Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.","Science (New York, N.Y.)","2004 Mar 5","Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C"
1496a1669,1677
> "O35714-1","30755607","Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.","Nature communications","2019 Feb 12","Galle-Treger L, Sankaranarayanan I, Hurrell BP, Howard E, Lo R, Maazi H, Lewis G, Banie H, Epstein AL, Hu P, Rehan VK, Gilliland FD, Allayee H, Soroosh P, Sharpe AH, Akbari O"
> "O35714-1","29623077","Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.","Frontiers in immunology","2018","Vashist N, Trittel S, Ebensen T, Chambers BJ, Guzman CA, Riese P"
> "O35714-1","28611044","Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells.","Cancer research","2017 Aug 15","Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, Sriram V, Bailey WJ, Herzyk D, McClanahan TK, Willingham A, Beebe AM, Sadekova S"
> "O35714-1","28649380","GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory.","Journal for immunotherapy of cancer","2017","Durham NM, Holoweckyj N, MacGill RS, McGlinchey K, Leow CC, Robbins SH"
> "O35714-1","11869690","CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.","Immunity","2002 Feb","McHugh RS, Whitters MJ, Piccirillo CA, Young DA, Shevach EM, Collins M, Byrne MC"
> "Q80YE7-1","29317503","ER-stress mobilization of death-associated protein kinase-1-dependent xenophagy counteracts mitochondria stress-induced epithelial barrier dysfunction.","The Journal of biological chemistry","2018 Mar 2","Lopes F, Keita AV, Saxena A, Reyes JL, Mancini NL, Al Rajabi A, Wang A, Baggio CH, Dicay M, van Dalen R, Ahn Y, Carneiro MBH, Peters NC, Rho JM, MacNaughton WK, Girardin SE, Jijon H, Philpott DJ, Soderholm JD, McKay DM"
> "Q80YE7-1","28731405","Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.","eLife","2017 Jul 21","McQueen J, Ryan TJ, McKay S, Marwick K, Baxter P, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJA, Grant SGN, McColl BW, Komiyama NH, Hardingham GE"
> "Q80YE7-1","28614711","DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific.","Cell reports","2017 Jun 13","Goodell DJ, Zaegel V, Coultrap SJ, Hell JW, Bayer KU"
> "Q80YE7-1","14530257","Antisense depletion of death-associated protein kinase promotes apoptosis.","The Journal of biological chemistry","2003 Dec 19","Jin Y, Gallagher PJ"
1501a1683,1684
> "Q60634-1","27993509","Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons.","Experimental neurology","2017 Mar","Bodrikov V, Pauschert A, Kochlamazashvili G, Stuermer CAO"
> "Q60634-1","26313572","Expression of Flotilin-2 and Acrosome Biogenesis Are Regulated by MiR-124 during Spermatogenesis.","PloS one","2015","Wu Y, Zhong A, Zheng H, Jiang M, Xia Z, Yu J, Chen L, Huang X"
1502a1686
> "E9PZ87-1","29238946","PAPP-A2 a new key regulator of growth.","Endokrynologia Polska","2017","Banaszak-Ziemska M, Niedziela M"
1520a1705,1706
> "Q91VH1-1","29194451","Adiponectin receptor 1 resists the decline of serum osteocalcin and GPRC6A expression in ovariectomized mice.","PloS one","2017","Lin YY, Chen CY, Ding ST"
> "Q91VH1-1","12802337","Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.","Nature","2003 Jun 12","Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T"
1535,1538d1720
< "Q8CCE9-1","27621446","E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 27","Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, Gayte L, Casas F, Pessemesse L, Heuillet M, Bellvert F, Portais JC, Berthet C, Bernex F, Brivet M, Boutron A, Le Cam L, Sardet C"
< "Q8CCE9-1","27621431","E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 27","Goguet-Rubio P, Seyran B, Gayte L, Bernex F, Sutter A, Delpech H, Linares LK, Riscal R, Repond C, Rodier G, Kirsh O, Touhami J, Noel J, Vincent C, Pirot N, Pavlovic G, Herault Y, Sitbon M, Pellerin L, Sardet C, Lacroix M, Le Cam L"
< "Q8CCE9-1","25843721","The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions.","Cell reports","2015 Apr 14","Rodier G, Kirsh O, Baraibar M, Houles T, Lacroix M, Delpech H, Hatchi E, Arnould S, Severac D, Dubois E, Caramel J, Julien E, Friguet B, Le Cam L, Sardet C"
< "Q8CCE9-1","25843717","E4F1 is a master regulator of CHK1-mediated functions.","Cell reports","2015 Apr 14","Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G"
1541,1542c1723
< "Q9QXS6-1","30700723","ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans.","Nature communications","2019 Jan 30","Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ"
< "Q9QXS6-1","12761245","Cell biological and biochemical characterization of drebrin complexes in mesangial cells and podocytes of renal glomeruli.","Journal of the American Society of Nephrology : JASN","2003 Jun","Peitsch WK, Hofmann I, Endlich N, Pratzel S, Kuhn C, Spring H, Grone HJ, Kriz W, Franke WW"
---
> "Q9Z2C5-1","28934386","Expression of the neuropathy-associated MTMR2 gene rescues MTM1-associated myopathy.","Human molecular genetics","2017 Oct 1","Raess MA, Cowling BS, Bertazzi DL, Kretz C, Rinaldi B, Xuereb JM, Kessler P, Romero NB, Payrastre B, Friant S, Laporte J"
1545a1727,1730
> "P70280-1","28392418","Spastin regulates VAMP7-containing vesicles trafficking in cortical neurons.","Biochimica et biophysica acta. Molecular basis of disease","2017 Jun","Plaud C, Joshi V, Marinello M, Pastre D, Galli T, Curmi PA, Burgo A"
> "Q64362-1","26110528","AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance.","PLoS genetics","2015 Jun","Burla R, Carcuro M, Raffa GD, Galati A, Raimondo D, Rizzo A, La Torre M, Micheli E, Ciapponi L, Cenci G, Cundari E, Musio A, Biroccio A, Cacchione S, Gatti M, Saggio I"
> "O54967-1","28189676","miR-24 represses metastasis of human osteosarcoma cells by targeting Ack1 via AKT/MMPs pathway.","Biochemical and biophysical research communications","2017 Apr 29","Liu Z, Liu Z, Zhang Y, Li Y, Liu B, Zhang K"
> "O54967-1","28188290","Activated Cdc42-associated kinase 1 (ACK1) binds the sterile alpha motif (SAM) domain of the adaptor SLP-76 and phosphorylates proximal tyrosines.","The Journal of biological chemistry","2017 Apr 14","Thaker YR, Recino A, Raab M, Jabeen A, Wallberg M, Fernandez N, Rudd CE"
1549,1552d1733
< "Q08048-1","30627913","Semaphorin 3A Negatively Affects Proliferation of Mouse Thymus Epithelial Cells In Vitro.","Bulletin of experimental biology and medicine","2019 Jan","Rutto KV, Ovsyukov KS, Kudryavtsev IV, Kiseleva EP"
< "Q08048-1","30401749","Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.","The Journal of biological chemistry","2018 Dec 28","Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He Y, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo ML, Sun Z"
< "Q08048-1","30103949","c-Fos is necessary for HGF-mediated gene regulation and cell migration in Schwann cells.","Biochemical and biophysical research communications","2018 Sep 18","Ko KR, Lee J, Nho B, Kim S"
< "Q08048-1","30066918","Hepatocyte growth factor exerts beneficial effects on mice with type II diabetesinduced chronic renal failure via the NFkappaB pathway.","Molecular medicine reports","2018 Sep","Cheng G, Tang X, Zhang J"
1554a1736,1737
> "Q8VDQ1-1","17449869","Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation.","The Journal of biological chemistry","2007 Jun 22","Chou WL, Chuang LM, Chou CC, Wang AH, Lawson JA, FitzGerald GA, Chang ZF"
> "Q8VDQ1-1","15229897","Crystal structure of a putative NADPH-dependent oxidoreductase (GI: 18204011) from mouse at 2.10 A resolution.","Proteins","2004 Aug 15","Levin I, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hampton E, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Reyes R, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA"
1556a1740
> "Q8R420-1","11940594","Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3.","The Journal of biological chemistry","2002 Jun 21","Mulugeta S, Gray JM, Notarfrancesco KL, Gonzales LW, Koval M, Feinstein SI, Ballard PL, Fisher AB, Shuman H"
1559,1562c1743,1744
< "Q925P2-1","27161904","CEACAM2 positively regulates integrin alphaIIbbeta3-mediated platelet functions.","Platelets","2016 Dec","Alshahrani MM, Kyriacou RP, O'Malley CJ, Heinrich G, Najjar SM, Jackson DE"
< "Q925P2-1","26586918","Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2).","The Journal of biological chemistry","2016 Jan 8","Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, Kim JK, Giovannucci DR, Najjar SM"
< "Q925P2-1","25085348","CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.","Blood","2014 Oct 9","Alshahrani MM, Yang E, Yip J, Ghanem SS, Abdallah SL, deAngelis AM, O'Malley CJ, Moheimani F, Najjar SM, Jackson DE"
< "Q925P2-1","24948196","CEACAM2-L on spermatids interacts with poliovirus receptor on Sertoli cells in mouse seminiferous epithelium.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2014 Sep","Salaheldeen E, Howida A, Wakayama T, Iida H"
---
> "Q99J31-1","27742778","Oligophrenin-1 regulates number, morphology and synaptic properties of adult-born inhibitory interneurons in the olfactory bulb.","Human molecular genetics","2016 Dec 1","Redolfi N, Galla L, Maset A, Murru L, Savoia E, Zamparo I, Gritti A, Billuart P, Passafaro M, Lodovichi C"
> "Q99J31-1","27146843","Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability.","Human molecular genetics","2016 Jun 1","Meziane H, Khelfaoui M, Morello N, Hiba B, Calcagno E, Reibel-Foisset S, Selloum M, Chelly J, Humeau Y, Riet F, Zanni G, Herault Y, Bienvenu T, Giustetto M, Billuart P"
1564a1747,1749
> "Q6ZPI0-1","26919559","Jade-1S phosphorylation induced by CK1alpha contributes to cell cycle progression.","Cell cycle (Georgetown, Tex.)","2016","Borgal L, Rinschen MM, Dafinger C, Liebrecht VI, Abken H, Benzing T, Schermer B"
> "Q6ZPI0-1","24097061","A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation.","The EMBO journal","2013 Oct 30","Wan G, Hu X, Liu Y, Han C, Sood AK, Calin GA, Zhang X, Lu X"
> "Q6ZPI0-1","14612400","Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.","Molecular and cellular biology","2003 Dec","Tzouanacou E, Tweedie S, Wilson V"
1566a1752,1759
> "Q8R1X6-1","28324774","Methylation changes of SIRT1, KLF4, DAPK1 and SPG20 in B-lymphocytes derived from follicular and diffuse large B-cell lymphoma.","Leukemia research","2017 Jun","Frazzi R, Zanetti E, Pistoni M, Tamagnini I, Valli R, Braglia L, Merli F"
> "Q8R1X6-1","27112432","Three cases of Troyer syndrome in two families of Filipino descent.","American journal of medical genetics. Part A","2016 Jul","Butler S, Helbig KL, Alcaraz W, Seaver LH, Hsieh DT, Rohena L"
> "Q8R1X6-1","24523286","The role of spartin and its novel ubiquitin binding region in DALIS occurrence.","Molecular biology of the cell","2014 Apr","Karlsson AB, Washington J, Dimitrova V, Hooper C, Shekhtman A, Bakowska JC"
> "Q8R1X6-1","22982304","Are alsin and spartin novel interaction partners?","Biochemical and biophysical research communications","2012 Oct 12","Cobanoglu G, Ozansoy M, Basak AN"
> "Q8R1X6-1","22619377","Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling.","Human molecular genetics","2012 Aug 15","Renvoise B, Stadler J, Singh R, Bakowska JC, Blackstone C"
> "Q8R1X6-1","21559443","SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis.","PloS one","2011 Apr 29","Joshi DC, Bakowska JC"
> "Q8R1X6-1","16036216","The Troyer syndrome (SPG20) protein spartin interacts with Eps15.","Biochemical and biophysical research communications","2005 Sep 9","Bakowska JC, Jenkins R, Pendleton J, Blackstone C"
> "Q8R242-1","22465033","Lysosomal di-N-acetylchitobiase-deficient mouse tissues accumulate Man2GlcNAc2 and Man3GlcNAc2.","Biochimica et biophysica acta","2012 Jul","Persichetti E, Klein K, Paciotti S, Lecointe K, Balducci C, Franken S, Duvet S, Matzner U, Roberti R, Hartmann D, Gieselmann V, Beccari T"
1572a1766
> "Q8BYJ6-1","27929607","Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking.","FEBS letters","2017 Jan","Zhou Z, Menzel F, Benninghoff T, Chadt A, Du C, Holman GD, Al-Hasani H"
1577,1586c1771
< "Q6NZL8-1","20042401","SCUBE1, a novel developmental gene involved in renal regeneration and repair.","Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","2010 May","Zhuang J, Deane JA, Yang RB, Li J, Ricardo SD"
< "Q6NZL8-1","19101956","Scube1 is expressed during facial development in the mouse.","Journal of experimental zoology. Part B, Molecular and developmental evolution","2009 Jul 15","Xavier GM, Sharpe PT, Cobourne MT"
< "Q6NZL8-1","18303018","Domain and functional analysis of a novel platelet-endothelial cell surface protein, SCUBE1.","The Journal of biological chemistry","2008 May 2","Tu CF, Yan YT, Wu SY, Djoko B, Tsai MT, Cheng CJ, Yang RB"
< "Q3UHC7-1","27476001","DAB2IP regulates EMT and metastasis of prostate cancer through targeting PROX1 transcription and destabilizing HIF1alpha protein.","Cellular signalling","2016 Nov","Wang B, Huang J, Zhou J, Hui K, Xu S, Fan J, Li L, Wang X, Hsieh JT, He D, Wu K"
< "Q3UHC7-1","26512963","DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis.","Cell death &amp; disease","2015 Oct 29","Zhou J, Ning Z, Wang B, Yun EJ, Zhang T, Pong RC, Fazli L, Gleave M, Zeng J, Fan J, Wang X, Li L, Hsieh JT, He D, Wu K"
< "Q3UHC7-1","26139244","AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis.","Cancer research","2015 Sep 1","Ji W, Li Y, He Y, Yin M, Zhou HJ, Boggon TJ, Zhang H, Min W"
< "Q3UHC7-1","26181199","AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment.","Cell death &amp; disease","2015 Jul 16","Xu J, Wan P, Wang M, Zhang J, Gao X, Hu B, Han J, Chen L, Sun K, Wu J, Wu X, Huang X, Chen J"
< "Q3UHC7-1","25995115","Single-molecule imaging of a three-component ordered actin disassembly mechanism.","Nature communications","2015 May 21","Jansen S, Collins A, Chin SM, Ydenberg CA, Gelles J, Goode BL"
< "Q3UHC7-1","18281285","AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response.","The Journal of biological chemistry","2008 May 2","Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W"
< "Q3UHC7-1","12877983","Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain.","Brain research. Molecular brain research","2003 Jul 23","Homayouni R, Magdaleno S, Keshvara L, Rice DS, Curran T"
---
> "P97931-1","28775312","Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.","Scientific reports","2017 Aug 3","Alsoe L, Sarno A, Carracedo S, Domanska D, Dingler F, Lirussi L, SenGupta T, Tekin NB, Jobert L, Alexandrov LB, Galashevskaya A, Rada C, Sandve GK, Rognes T, Krokan HE, Nilsen H"
1590,1594d1774
< "Q80VP1-1","25871009","Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.","Nature communications","2015 Mar 16","Chang B, Tessneer KL, McManus J, Liu X, Hahn S, Pasula S, Wu H, Song H, Chen Y, Cai X, Dong Y, Brophy ML, Rahman R, Ma JX, Xia L, Chen H"
< "Q80VP1-1","25314967","Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.","Science signaling","2014 Oct 14","Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H"
< "Q80VP1-1","23187125","Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.","The Journal of clinical investigation","2012 Dec","Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, Newton G, Luscinskas F, Sun X, Towner R, Lupu F, Xia L, Cremona O, De Camilli P, Min W, Chen H"
< "Q80VP1-1","19666558","Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.","Proceedings of the National Academy of Sciences of the United States of America","2009 Aug 18","Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O"
< "Q80VP1-1","16574660","Clathrin-mediated endocytosis of the epithelial sodium channel. Role of epsin.","The Journal of biological chemistry","2006 May 19","Wang H, Traub LM, Weixel KM, Hawryluk MJ, Shah N, Edinger RS, Perry CJ, Kester L, Butterworth MB, Peters KW, Kleyman TR, Frizzell RA, Johnson JP"
1597a1778,1785
> "Q9Z188-1","30317528","DYRK1B regulates Hedgehog-induced microtubule acetylation.","Cellular and molecular life sciences : CMLS","2019 Jan","Singh R, Holz PS, Roth K, Hupfer A, Meissner W, Muller R, Buchholz M, Gress TM, Elsasser HP, Jacob R, Lauth M"
> "Q9Z188-1","29030970","Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.","Journal of cellular physiology","2018 May","Perez-Sanchez G, Jimenez A, Quezada-Ramirez MA, Estudillo E, Ayala-Sarmiento AE, Mendoza-Hernandez G, Hernandez-Soto J, Hernandez-Hernandez FC, Cazares-Raga FE, Segovia J"
> "Q9Z188-1","24312406","Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.","PloS one","2013","Tsioras K, Papastefanaki F, Politis PK, Matsas R, Gaitanou M"
> "Q9Z188-1","22711815","Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.","Proceedings of the National Academy of Sciences of the United States of America","2012 Jul 3","Masuda T, Itoh K, Higashitsuji H, Higashitsuji H, Nakazawa N, Sakurai T, Liu Y, Tokuchi H, Fujita T, Zhao Y, Nishiyama H, Tanaka T, Fukumoto M, Ikawa M, Okabe M, Fujita J"
> "Q9Z188-1","18818203","G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.","The Journal of biological chemistry","2008 Dec 5","Janumyan Y, Cui Q, Yan L, Sansam CG, Valentin M, Yang E"
> "Q9Z188-1","12902328","Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation.","The Journal of biological chemistry","2003 Oct 17","Deng X, Ewton DZ, Pawlikowski B, Maimone M, Friedman E"
> "Q9Z188-1","12384504","The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.","The Journal of biological chemistry","2002 Dec 20","Lim S, Zou Y, Friedman E"
> "Q1HKZ5-1","28641113","Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.","Neuron","2017 Jun 21","Welsbie DS, Mitchell KL, Jaskula-Ranga V, Sluch VM, Yang Z, Kim J, Buehler E, Patel A, Martin SE, Zhang PW, Ge Y, Duan Y, Fuller J, Kim BJ, Hamed E, Chamling X, Lei L, Fraser IDC, Ronai ZA, Berlinicke CA, Zack DJ"
1600a1789
> "Q5SPX1-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
1601a1791,1797
> "Q80XE1-2","29118104","Conditional Deletion of Ric-8b in Olfactory Sensory Neurons Leads to Olfactory Impairment.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Dec 13","Machado CF, Nagai MH, Lyra CS, Reis-Silva TM, Xavier AM, Glezer I, Felicio LF, Malnic B"
> "Q80XE1-2","26062014","Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis.","PloS one","2015","Saare M, Lulla S, Tonissoo T, Meier R, Kask K, Ruisu K, Karis A, Salumets A, Pooga M"
> "Q80XE1-2","24585571","A functional N-terminal domain in C/EBPbeta-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts.","Journal of cellular physiology","2014 Oct","Aguilar R, Grandy R, Meza D, Sepulveda H, Pihan P, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M"
> "Q80XE1-2","24134321","Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric-8B in Gs suppression by Gq signal.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2013 Dec","Jenie RI, Nishimura M, Fujino M, Nakaya M, Mizuno N, Tago K, Kurose H, Itoh H"
> "Q80XE1-2","20133939","Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.","The Journal of biological chemistry","2010 Apr 9","Nagai Y, Nishimura A, Tago K, Mizuno N, Itoh H"
> "Q80XE1-2","18462949","Ric-8B interacts with G alpha olf and G gamma 13 and co-localizes with G alpha olf, G beta 1 and G gamma 13 in the cilia of olfactory sensory neurons.","Molecular and cellular neurosciences","2008 Jul","Kerr DS, Von Dannecker LE, Davalos M, Michaloski JS, Malnic B"
> "Q80XE1-2","16754875","Ric-8B promotes functional expression of odorant receptors.","Proceedings of the National Academy of Sciences of the United States of America","2006 Jun 13","Von Dannecker LE, Mercadante AF, Malnic B"
1605d1800
< "Q6P1D5-1","27716410","Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.","Molecular neurodegeneration","2016 Oct 5","Pigoni M, Wanngren J, Kuhn PH, Munro KM, Gunnersen JM, Takeshima H, Feederle R, Voytyuk I, De Strooper B, Levasseur MD, Hrupka BJ, Muller SA, Lichtenthaler SF"
1607,1618d1801
< "O54946-1","21972064","Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.","Developmental dynamics : an official publication of the American Association of Anatomists","2011 Nov","Watson ED, Hughes M, Simmons DG, Natale DR, Sutherland AE, Cross JC"
< "O54946-1","19777589","Neural stem cell self-renewal requires the Mrj co-chaperone.","Developmental dynamics : an official publication of the American Association of Anatomists","2009 Oct","Watson ED, Mattar P, Schuurmans C, Cross JC"
< "O54946-1","18373498","The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells.","The Biochemical journal","2008 Jul 15","Zhang Y, Yang Z, Cao Y, Zhang S, Li H, Huang Y, Ding YQ, Liu X"
< "Q8VBT3-1","23817038","Monocytic expression of osteoclast-associated receptor (OSCAR) is induced in atherosclerotic mice and regulated by oxidized low-density lipoprotein in vitro.","Biochemical and biophysical research communications","2013 Jul 26","Sinningen K, Rauner M, Goettsch C, Al-Fakhri N, Schoppet M, Hofbauer LC"
< "Q8VBT3-1","21841309","OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice.","The Journal of clinical investigation","2011 Sep","Barrow AD, Raynal N, Andersen TL, Slatter DA, Bihan D, Pugh N, Cella M, Kim T, Rho J, Negishi-Koga T, Delaisse JM, Takayanagi H, Lorenzo J, Colonna M, Farndale RW, Choi Y, Trowsdale J"
< "Q8VBT3-1","18762192","Upstream stimulatory factors regulate OSCAR gene expression in RANKL-mediated osteoclast differentiation.","Journal of molecular biology","2008 Nov 14","Kim JH, Kim K, Jin HM, Youn BU, Song I, Choi HS, Kim N"
< "Q8VBT3-1","17442941","Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor.","Journal of immunology (Baltimore, Md. : 1950)","2007 May 1","Kim K, Lee J, Kim JH, Jin HM, Zhou B, Lee SY, Kim N"
< "Q8VBT3-1","16109714","Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis.","The Journal of biological chemistry","2005 Oct 21","Kim K, Kim JH, Lee J, Jin HM, Lee SH, Fisher DE, Kook H, Kim KK, Choi Y, Kim N"
< "Q8VBT3-1","16046394","Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis.","The Journal of biological chemistry","2005 Sep 23","Kim Y, Sato K, Asagiri M, Morita I, Soma K, Takayanagi H"
< "Q8VBT3-1","15184345","Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).","International immunology","2004 Jul","Ishikawa S, Arase N, Suenaga T, Saita Y, Noda M, Kuriyama T, Arase H, Saito T"
< "Q8VBT3-1","12695521","Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.","The Journal of biological chemistry","2003 Jun 27","So H, Rho J, Jeong D, Park R, Fisher DE, Ostrowski MC, Choi Y, Kim N"
< "P16305-1","29673739","Association of serotonin and GABA pathway gene polymorphisms with alcohol dependence: A preliminary study.","Asian journal of psychiatry","2019 Jan","Sahni S, Tickoo M, Gupta R, Vaswani M, Ambekar A, Grover T, Sharma A"
1620a1804
> "Q9CQX5-1","28244141","Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage.","Journal of neuroscience research","2017 Oct","Ohnishi M, Ochiai H, Matsuoka K, Akagi M, Nakayama Y, Shima A, Uda A, Matsuoka H, Kamishikiryo J, Michihara A, Inoue A"
1621a1806,1807
> "P32766-1","22827436","In vitro regulatory effect of epididymal serpin CRES on protease activity of proprotein convertase PC4/PCSK4.","Current molecular medicine","2012 Sep","Mishra P, Qiu Q, Gruslin A, Hidaka Y, Mbikay M, Basak A"
> "P26187-1","27618784","mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.","Aging cell","2017 Feb","Dominick G, Bowman J, Li X, Miller RA, Garcia GG"
1627a1814,1815
> "P27546-1","30327268","Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.","EBioMedicine","2018 Nov","Li L, Zhang Q, Zhang X, Zhang J, Wang X, Ren J, Jia J, Zhang D, Jiang X, Zhang J, Mei H, Chen B, Hu J, Huang Y"
> "P27546-1","25898002","A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation.","eLife","2015 Apr 21","Mogessie B, Roth D, Rahil Z, Straube A"
1633a1822,1830
> "Q4KMM3-1","27036366","The antioxidant protein Oxr1 influences aspects of mitochondrial morphology.","Free radical biology &amp; medicine","2016 Jun","Wu Y, Davies KE, Oliver PL"
> "Q4KMM3-1","25753484","Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis.","Brain : a journal of neurology","2015 May","Liu KX, Edwards B, Lee S, Finelli MJ, Davies B, Davies KE, Oliver PL"
> "Q8C9B9-1","28330622","DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells.","Stem cell reports","2017 Apr 11","Futterer A, de Celis J, Navajas R, Almonacid L, Gutierrez J, Talavera-Gutierrez A, Pacios-Bras C, Bernascone I, Martin-Belmonte F, Martinez-A C"
> "Q8C9B9-1","25825751","Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice.","Proceedings of the National Academy of Sciences of the United States of America","2015 Apr 14","Villares R, Gutierrez J, Futterer A, Trachana V, Gutierrez del Burgo F, Martinez-A C"
> "Q8C9B9-1","24667272","Dido3-dependent HDAC6 targeting controls cilium size.","Nature communications","2014 Mar 25","Sanchez de Diego A, Alonso Guerrero A, Martinez-A C, van Wely KH"
> "Q8C9B9-1","24347171","The death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal.","The Journal of biological chemistry","2014 Feb 21","Liu Y, Kim H, Liang J, Lu W, Ouyang B, Liu D, Songyang Z"
> "Q8C9B9-1","19557426","Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis.","Chromosoma","2009 Oct","Prieto I, Kouznetsova A, Futterer A, Trachana V, Leonardo E, Alonso Guerrero A, Cano Gamero M, Pacios-Bras C, Leh H, Buckle M, Garcia-Gallo M, Kremer L, Serrano A, Roncal F, Albar JP, Barbero JL, Martinez-A C, van Wely KH"
> "Q8C9B9-1","17299043","Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability.","Proceedings of the National Academy of Sciences of the United States of America","2007 Feb 20","Trachana V, van Wely KH, Guerrero AA, Futterer A, Martinez-A C"
> "Q8C9B9-1","16127461","Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms.","The Journal of clinical investigation","2005 Sep","Futterer A, Campanero MR, Leonardo E, Criado LM, Flores JM, Hernandez JM, San Miguel JF, Martinez-A C"
1636a1834,1837
> "Q70IV5-1","25567810","Myopathic changes in murine skeletal muscle lacking synemin.","American journal of physiology. Cell physiology","2015 Mar 15","Garcia-Pelagio KP, Muriel J, O'Neill A, Desmond PF, Lovering RM, Lund L, Bond M, Bloch RJ"
> "Q70IV5-1","17654553","Synemin expression in brain.","Muscle &amp; nerve","2007 Oct","Mizuno Y, Guyon JR, Okamoto K, Kunkel LM"
> "Q70IV5-1","17356066","Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.","Journal of cell science","2007 Apr 1","Jing R, Wilhelmsson U, Goodwill W, Li L, Pan Y, Pekny M, Skalli O"
> "Q70IV5-1","16817202","Different expression of synemin isoforms in glia and neurons during nervous system development.","Glia","2006 Aug 15","Izmiryan A, Cheraud Y, Khanamiryan L, Leterrier JF, Federici T, Peltekian E, Moura-Neto V, Paulin D, Li Z, Xue ZG"
1639a1841
> "Q78ZA7-1","21333655","Interaction between nucleosome assembly protein 1-like family members.","Journal of molecular biology","2011 Apr 15","Attia M, Forster A, Rachez C, Freemont P, Avner P, Rogner UC"
1649,1653c1851
< "E9PYI1-1","28522536","A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568.","Science (New York, N.Y.)","2017 May 19","Yang P, Wang Y, Hoang D, Tinkham M, Patel A, Sun MA, Wolf G, Baker M, Chien HC, Lai KN, Cheng X, Shen CJ, Macfarlan TS"
< "E9PYI1-1","23071813","Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage.","PloS one","2012","Chien HC, Wang HY, Su YN, Lai KY, Lu LC, Chen PC, Tsai SF, Wu CI, Hsieh WS, Shen CK"
< "E9PYI1-1","22110054","TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.","Development (Cambridge, England)","2011 Dec","Shibata M, Blauvelt KE, Liem KF Jr, Garcia-Garcia MJ"
< "E9PYI1-1","21094155","The mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesis.","Developmental biology","2011 Jan 15","Shibata M, Garcia-Garcia MJ"
< "E9PYI1-1","18701545","Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.","Development (Cambridge, England)","2008 Sep","Garcia-Garcia MJ, Shibata M, Anderson KV"
---
> "Q3U1J1-1","17041757","Apoptosis promoted by up-regulation of TFPT (TCF3 fusion partner) appears p53 independent, cell type restricted and cell density influenced.","Apoptosis : an international journal on programmed cell death","2006 Dec","Franchini C, Fontana F, Minuzzo M, Babbio F, Privitera E"
1656c1854
< "Q8BYK6-1","30591559","RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation.","Proceedings of the National Academy of Sciences of the United States of America","2019 Jan 15","Zhang Y, Wang X, Zhang X, Wang J, Ma Y, Zhang L, Cao X"
---
> "O88487-1","25015291","Interaction of SQSTM1 with the motor protein dynein--SQSTM1 is required for normal dynein function and trafficking.","Journal of cell science","2014 Sep 15","Calderilla-Barbosa L, Seibenhener ML, Du Y, Diaz-Meco MT, Moscat J, Yan J, Wooten MW, Wooten MC"
1660a1859,1863
> "Q3UUJ4-1","21903876","Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle.","Journal of applied physiology (Bethesda, Md. : 1985)","2011 Dec","Smith CD, Compton RA, Bowler JS, Kemp JT, Sudweeks SN, Thomson DM, Winder WW"
> "Q3UUJ4-1","20424326","STRADalpha deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice.","The Journal of clinical investigation","2010 May","Orlova KA, Parker WE, Heuer GG, Tsai V, Yoon J, Baybis M, Fenning RS, Strauss K, Crino PB"
> "Q9DC40-1","24657168","Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.","Molecular cell","2014 Apr 10","Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH"
> "Q9DC40-1","20864032","CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.","Molecular cell","2010 Sep 24","Horejsi Z, Takai H, Adelman CA, Collis SJ, Flynn H, Maslen S, Skehel JM, de Lange T, Boulton SJ"
> "Q9DC40-1","18160036","Tel2 regulates the stability of PI3K-related protein kinases.","Cell","2007 Dec 28","Takai H, Wang RC, Takai KK, Yang H, de Lange T"
1672,1675c1875
< "Q62406-1","30361091","Down-regulation of IRAK1 attenuates podocyte apoptosis in diabetic nephropathy through PI3K/Akt signaling pathway.","Biochemical and biophysical research communications","2018 Nov 30","Zhang Y, Chen X, Yuan L, Zhang Y, Wu J, Guo N, Chen X, Liu J"
< "Q62406-1","30078230","Globular Adiponectin Exerts a Pro-Inflammatory Effect via IkappaB/NF-kappaB Pathway Activation and Anti-Inflammatory Effect by IRAK-1 Downregulation.","Molecules and cells","2018 Aug 31","Lee KH, Jeong J, Woo J, Lee CH, Yoo CG"
< "Q62406-1","29995830","Endotoxin Tolerant Dendritic Cells Suppress Inflammatory Responses in Splenocytes via Interleukin-1 Receptor Associated Kinase (IRAK)-M and Programmed Death-Ligand 1 (PDL-1).","Medical science monitor : international medical journal of experimental and clinical research","2018 Jul 11","Zhou Y, Xia Q, Wang X, Fu S"
< "Q62406-1","29804558","Anti-inflammatory effects of a novel compound, MPQP, through the inhibition of IRAK1 signaling pathways in LPS-stimulated RAW 264.7 macrophages.","BMB reports","2018 Jun","Kim BR, Cho YC, Cho S"
---
> "Q9JIL6-1","15086536","The RAIG family member, GPRC5D, is associated with hard-keratinized structures.","The Journal of investigative dermatology","2004 Mar","Inoue S, Nambu T, Shimomura T"
1688,1694c1888,1889
< "Q80U23-1","28891816","Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer.","The Journal of clinical investigation","2017 Oct 2","Caino MC, Seo JH, Wang Y, Rivadeneira DB, Gabrilovich DI, Kim ET, Weeraratna AT, Languino LR, Altieri DC"
< "Q80U23-1","28472658","Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions.","Neuron","2017 May 3","Lin MY, Cheng XT, Tammineni P, Xie Y, Zhou B, Cai Q, Sheng ZH"
< "Q80U23-1","27370822","Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring.","Molecular brain","2016 Jul 2","Park C, Lee SA, Hong JH, Suh Y, Park SJ, Suh BK, Woo Y, Choi J, Huh JW, Kim YM, Park SK"
< "Q80U23-1","25834054","Deletion of mitochondrial anchoring protects dysmyelinating shiverer: implications for progressive MS.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Apr 1","Joshi DC, Zhang CL, Lin TM, Gusain A, Harris MG, Tree E, Yin Y, Wu C, Sheng ZH, Dempsey RJ, Fabry Z, Chiu SY"
< "Q80U23-1","23857772","Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport.","The Journal of cell biology","2013 Jul 22","Chen Y, Sheng ZH"
< "Q80U23-1","19641106","Dynein light chain LC8 regulates syntaphilin-mediated mitochondrial docking in axons.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2009 Jul 29","Chen YM, Gerwin C, Sheng ZH"
< "Q80U23-1","18191227","Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.","Cell","2008 Jan 11","Kang JS, Tian JH, Pan PY, Zald P, Li C, Deng C, Sheng ZH"
---
> "Q61419-1","29196263","Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute.","Biochemical and biophysical research communications","2018 Jan 1","Bousquet PA, Sandvik JA, Jeppesen Edin NF, Krengel U"
> "Q923T7-1","29466708","GNIP1 E3 ubiquitin ligase is a novel player in regulating glycogen metabolism in skeletal muscle.","Metabolism: clinical and experimental","2018 Jun","Montori-Grau M, Pedreira-Casahuga R, Boyer-Diaz Z, Lassot I, Garcia-Martinez C, Orozco A, Cebria J, Osorio-Conles O, Chacon MR, Vendrell J, Vazquez-Carrera M, Desagher S, Jimenez-Chillaron JC, Gomez-Foix AM"
1695a1891,1892
> "A2AT37-1","27149095","Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.","PLoS genetics","2016 May","Fanourgakis G, Lesche M, Akpinar M, Dahl A, Jessberger R"
> "A2AT37-1","20657840","UPF2 is a critical regulator of liver development, function and regeneration.","PloS one","2010 Jul 19","Thoren LA, Norgaard GA, Weischenfeldt J, Waage J, Jakobsen JS, Damgaard I, Bergstrom FC, Blom AM, Borup R, Bisgaard HC, Porse BT"
1702a1900,1904
> "Q149L7-1","26694968","CRTAM determines the CD4+ cytotoxic T lymphocyte lineage.","The Journal of experimental medicine","2016 Jan 11","Takeuchi A, Badr Mel S, Miyauchi K, Ishihara C, Onishi R, Guo Z, Sasaki Y, Ike H, Takumi A, Tsuji NM, Murakami Y, Katakai T, Kubo M, Saito T"
> "Q149L7-1","24687959","CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection.","The Journal of experimental medicine","2014 Apr 7","Cortez VS, Cervantes-Barragan L, Song C, Gilfillan S, McDonald KG, Tussiwand R, Edelson BT, Murakami Y, Murphy KM, Newberry RD, Sibley LD, Colonna M"
> "Q149L7-1","21572449","Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancer model by boosting the interaction between TSLC1 and CRTAM.","Cellular &amp; molecular immunology","2011 Jul","Cai Y, Xiong S, Zheng Y, Luo F, Jiang P, Chu Y"
> "Q149L7-1","15811952","The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.","Blood","2005 Aug 1","Boles KS, Barchet W, Diacovo T, Cella M, Colonna M"
> "Q149L7-1","15781451","Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.","The Journal of biological chemistry","2005 Jun 10","Galibert L, Diemer GS, Liu Z, Johnson RS, Smith JL, Walzer T, Comeau MR, Rauch CT, Wolfson MF, Sorensen RA, Van der Vuurst de Vries AR, Branstetter DG, Koelling RM, Scholler J, Fanslow WC, Baum PR, Derry JM, Yan W"
1706c1908
< "P0DOV1-1","23145002","Apoptosis-related gene expression profiles of mouse ESCs and maGSCs: role of Fgf4 and Mnda in pluripotent cell responses to genotoxicity.","PloS one","2012","Khromov T, Dressel R, Siamishi I, Nolte J, Opitz L, Engel W, Pantakani DV"
---
> "Q8BKT8-1","23182369","Knockdown of UCHL5IP causes abnormalities in gamma-tubulin localisation, spindle organisation and chromosome alignment in mouse oocyte meiotic maturation.","Reproduction, fertility, and development","2013","Wang YP, Qi ST, Wei Y, Ge ZJ, Chen L, Hou Y, Ouyang YC, Schatten H, Zhao JG, Sun QY"
1709a1912
> "A2ABV5-1","20194623","MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.","Molecular and cellular biology","2010 May","Grontved L, Madsen MS, Boergesen M, Roeder RG, Mandrup S"
1713,1714c1916
< "Q9QWH1-1","24091011","SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing.","Developmental cell","2013 Sep 30","Isono K, Endo TA, Ku M, Yamada D, Suzuki R, Sharif J, Ishikura T, Toyoda T, Bernstein BE, Koseki H"
< "Q9QWH1-1","23605804","Expression pattern and functional role of Phc2 during activation of helper T cells after antigenic stimulation.","In vitro cellular &amp; developmental biology. Animal","2013 May","Cho KW, Bae J, Lee SJ, Chun T"
---
> "G3X939-1","29167115","Epigenetic modulation of intestinal Na(+)/H(+) exchanger-3 expression.","American journal of physiology. Gastrointestinal and liver physiology","2018 Mar 1","Kumar A, Malhotra P, Coffing H, Priyamvada S, Anbazhagan AN, Krishnan HR, Gill RK, Alrefai WA, Gavin DP, Pandey SC, Dudeja PK, Saksena S"
1718,1723d1919
< "Q8CJ53-1","28720386","Cdc42-interacting protein 4 silencing relieves pulmonary fibrosis in STZ-induced diabetic mice via the Wnt/GSK-3beta/beta-catenin pathway.","Experimental cell research","2017 Oct 1","Zhang X, Liu Y, Shao R, Li W"
< "Q8CJ53-1","23881916","Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling.","Blood","2013 Sep 5","Chen Y, Aardema J, Kale S, Whichard ZL, Awomolo A, Blanchard E, Chang B, Myers DR, Ju L, Tran R, Reece D, Christensen H, Boukour S, Debili N, Strom TS, Rawlings D, Vazquez FX, Voth GA, Zhu C, Kahr WH, Lam WA, Corey SJ"
< "Q8CJ53-1","23572514","CIP4 coordinates with phospholipids and actin-associated proteins to localize to the protruding edge and produce actin ribs and veils.","Journal of cell science","2013 Jun 1","Saengsawang W, Taylor KL, Lumbard DC, Mitok K, Price A, Pietila L, Gomez TM, Dent EW"
< "Q8CJ53-1","22920438","Inhibition of Cdc42-interacting protein 4 (CIP4) impairs osteosarcoma tumor progression.","Current cancer drug targets","2013 Jan","Koshkina NV, Yang G, Kleinerman ES"
< "Q8CJ53-1","22361215","The F-BAR protein CIP4 inhibits neurite formation by producing lamellipodial protrusions.","Current biology : CB","2012 Mar 20","Saengsawang W, Mitok K, Viesselmann C, Pietila L, Lumbard DC, Corey SJ, Dent EW"
< "Q8CJ53-1","12054674","Identification and genetic analysis of human and mouse activated Cdc42 interacting protein-4 isoforms.","Biochemical and biophysical research communications","2002 May 24","Wang L, Rudert WA, Grishin A, Dombrosky-Ferlan P, Sullivan K, Deng X, Whitcomb D, Corey S"
1725,1726c1921,1922
< "O88879-1","29596528","Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.","PloS one","2018","Tong H, Miyake Y, Mi-Ichi F, Iwakura Y, Hara H, Yoshida H"
< "O88879-1","27580417","microRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1.","Antioxidants &amp; redox signaling","2017 Apr 10","Lin HC, Liu SY, Yen EY, Li TK, Lai IR"
---
> "Q8BPP5-1","23987510","Lypd6 enhances Wnt/beta-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains.","Developmental cell","2013 Aug 26","Ozhan G, Sezgin E, Wehner D, Pfister AS, Kuhl SJ, Kagermeier-Schenk B, Kuhl M, Schwille P, Weidinger G"
> "Q920M5-1","24523531","Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2014 Feb 12","Chen Y, Ip FC, Shi L, Zhang Z, Tang H, Ng YP, Ye WC, Fu AK, Ip NY"
1730a1927
> "P26043-1","28893864","The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.","EMBO reports","2017 Nov","Vogl C, Butola T, Haag N, Hausrat TJ, Leitner MG, Moutschen M, Lefebvre PP, Speckmann C, Garrett L, Becker L, Fuchs H, Hrabe de Angelis M, Nietzsche S, Kessels MM, Oliver D, Kneussel M, Kilimann MW, Strenzke N"
1731a1929
> "P61205-1","26067373","ADP-Ribosylation Factor 3 Mediates Cytidine-Phosphate-Guanosine Oligodeoxynucleotide-Induced Responses by Regulating Toll-Like Receptor 9 Trafficking.","Journal of innate immunity","2015","Wu JY, Kuo CC"
1736,1738d1933
< "Q60631-1","30183074","Murine eosinophil development and allergic lung eosinophilia are largely dependent on the signaling adaptor GRB2.","European journal of immunology","2018 Nov","Willebrand R, Dietschmann A, Nitschke L, Krappmann S, Voehringer D"
< "Q60631-1","28964849","Grb2 regulates the proliferation of hematopoietic stem and progenitors cells.","Biochimica et biophysica acta. Molecular cell research","2017 Dec","Frelin C, Ofran Y, Ruston J, Hayun M, Derdikman Y, Khier Y, Rozales K, Brenner B, Iscove N, Pawson T, Louria-Hayon I"
< "Q60631-1","28455498","Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner.","Scientific reports","2017 Apr 28","Arya R, Dangi RS, Makwana PK, Kumar A, Upadhyay SK, Sundd M"
1741a1937
> "P55098-1","27597759","PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation.","The Journal of cell biology","2016 Sep 12","Sargent G, van Zutphen T, Shatseva T, Zhang L, Di Giovanni V, Bandsma R, Kim PK"
1746a1943
> "Q9R097-1","30193734","Grhl2 regulation of SPINT1 expression controls salivary gland development.","Biochemical and biophysical research communications","2018 Sep 26","Matsushita T, Sakai M, Yoshida H, Morita S, Hieda Y, Sakai T"
1753,1759c1950,1953
< "Q9EPK2-1","26936825","ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.","Human molecular genetics","2016 May 15","Wright ZC, Singh RK, Alpino R, Goldberg AF, Sokolov M, Ramamurthy V"
< "Q9EPK2-1","26358772","Long-term rescue of cone photoreceptor degeneration in retinitis pigmentosa 2 (RP2)-knockout mice by gene replacement therapy.","Human molecular genetics","2015 Nov 15","Mookherjee S, Hiriyanna S, Kaneshiro K, Li L, Li Y, Li W, Qian H, Li T, Khanna H, Colosi P, Swaroop A, Wu Z"
< "Q9EPK2-1","26383048","Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice.","Cytoskeleton (Hoboken, N.J.)","2015 Sep","Li L, Rao KN, Zheng-Le Y, Hurd TW, Lillo C, Khanna H"
< "Q9EPK2-1","23745007","Ablation of the X-linked retinitis pigmentosa 2 (Rp2) gene in mice results in opsin mislocalization and photoreceptor degeneration.","Investigative ophthalmology &amp; visual science","2013 Jul 2","Li L, Khan N, Hurd T, Ghosh AK, Cheng C, Molday R, Heckenlively JR, Swaroop A, Khanna H"
< "Q9EPK2-1","20106869","The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium.","Human molecular genetics","2010 Apr 1","Evans RJ, Schwarz N, Nagel-Wolfrum K, Wolfrum U, Hardcastle AJ, Cheetham ME"
< "Q3U285-1","25366156","Splicing variants of NOL4 differentially regulate the transcription activity of Mlr1 and Mlr2 in cultured cells.","Zoological science","2014 Nov","Takayanagi-Kiya S, Misawa-Hojo K, Kiya T, Kunieda T, Kubo T"
< "Q3U285-1","12560079","Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1).","FEBS letters","2003 Jan 30","Kunieda T, Park JM, Takeuchi H, Kubo T"
---
> "O89112-1","28106097","LanCL proteins are not Involved in Lanthionine Synthesis in Mammals.","Scientific reports","2017 Jan 20","He C, Zeng M, Dutta D, Koh TH, Chen J, van der Donk WA"
> "O88559-1","30315824","Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.","Experimental hematology","2019 Jan","Chen Y, Jones KL, Anastassiadis K, Kranz A, Stewart AF, Grembecka J, Meyerson M, Ernst P"
> "O88559-1","30099020","Mechanism of MEN1 gene in radiation-induced pulmonary fibrosis in mice.","Gene","2018 Dec 15","Wei W, Zhang HY, Gong XK, Dong Z, Chen ZY, Wang R, Yi JX, Shen YN, Jin SZ"
> "O88559-1","30120246","The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation.","Nature communications","2018 Aug 17","Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, Takemori A, Matsuda S, Kanoh M, Imai Y, Yasukawa M, Yamashita M"
1777a1972
> "Q9QYJ7-1","15252030","Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2.","The Journal of biological chemistry","2004 Oct 1","Chen HH, Luche R, Wei B, Tonks NK"
1780,1781c1975,1976
< "Q8BG05-1","22546510","Expression profile and interactions of hnRNP A3 within hnRNP/mRNP complexes in mammals.","Archives of biochemistry and biophysics","2012 Jul 15","Papadopoulou C, Boukakis G, Ganou V, Patrinou-Georgoula M, Guialis A"
< "Q8BG05-1","20885981","Heterogeneous nuclear ribonucleoprotein A3 is the liver nuclear protein binding to age related increase element RNA of the factor IX gene.","PloS one","2010 Sep 24","Hamada T, Kurachi S, Kurachi K"
---
> "Q9CZ30-1","27481995","OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression.","Molecular and cellular biology","2016 Oct 15","Ding Z, Liu Y, Rubio V, He J, Minze LJ, Shi ZZ"
> "Q9CZ30-1","26984302","Metal mixture (As-Cd-Pb)-induced cell transformation is modulated by OLA1.","Mutagenesis","2016 Jul","Martinez-Baeza E, Rojas E, Valverde M"
1783,1786c1978,1985
< "O70628-1","29505961","Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.","Neurobiology of aging","2018 May","Patel NS, Klett J, Pilarzyk K, Lee DI, Kass D, Menniti FS, Kelly MP"
< "O70628-1","25799991","Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.","Nature","2015 Mar 26","Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA"
< "O70628-1","22596207","The effect of phosphodiesterase inhibitors on the extinction of cocaine-induced conditioned place preference in mice.","Journal of psychopharmacology (Oxford, England)","2012 Oct","Liddie S, Anderson KL, Paz A, Itzhak Y"
< "O70628-1","9624146","Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase.","The Journal of biological chemistry","1998 Jun 19","Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB"
---
> "Q5NBU8-1","29132171","Metabolic Endotoxemia-Activated Macrophages Promote Pancreatic beta Cell Death via IFNbeta-Xaf1 Pathway.","Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme","2018 Feb","Tsuruta M, Iwashita M, Shinjo T, Matsunaga H, Yamashita A, Nishimura F"
> "Q5NBU8-1","27097110","XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bbeta-mediated apoptosis.","Oncotarget","2016 Jun 7","Choo Z, Koh RY, Wallis K, Koh TJ, Kuick CH, Sobrado V, Kenchappa RS, Loh AH, Soh SY, Schlisio S, Chang KT, Chen ZX"
> "Q5NBU8-1","18192275","Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation.","The Journal of biological chemistry","2008 Mar 14","Bai Y, Ahmad U, Wang Y, Li JH, Choy JC, Kim RW, Kirkiles-Smith N, Maher SE, Karras JG, Bennett CF, Bothwell AL, Pober JS, Tellides G"
> "Q5NBU8-1","18544999","XIAP-associated factor 1 (XAF1) suppresses angiogenesis in mouse endothelial cells.","Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine","2008","Qiao L, Gu Q, Dai Y, Shen Z, Liu X, Qi R, Ma J, Zou B, Li Z, Lan HY, Wong BC"
> "Q9D8B6-1","30366982","FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.","The Journal of biological chemistry","2018 Dec 21","Yien YY, Shi J, Chen C, Cheung JTM, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon LI, Palis J, Burke MD, Bauer DE, Orkin SH, Koehler CM, Phillips JD, Kaplan J, Ward DM, Lodish HF, Paw BH"
> "P13864-1","21163962","Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.","Science (New York, N.Y.)","2011 Feb 25","Song J, Rechkoblit O, Bestor TH, Patel DJ"
> "P13864-1","17371843","Biological functions of DNA methyltransferase 1 require its methyltransferase activity.","Molecular and cellular biology","2007 Jun","Damelin M, Bestor TH"
> "P13864-1","15634679","Stage-by-stage change in DNA methylation status of Dnmt1 locus during mouse early development.","The Journal of biological chemistry","2005 Mar 11","Ko YG, Nishino K, Hattori N, Arai Y, Tanaka S, Shiota K"
1794d1992
< "Q61137-1","11861479","Mice that lack astrotactin have slowed neuronal migration.","Development (Cambridge, England)","2002 Feb","Adams NC, Tomoda T, Cooper M, Dietz G, Hatten ME"
1802,1805c2000,2005
< "Q9QYP6-1","23610142","Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation.","Journal of immunology (Baltimore, Md. : 1950)","2013 Jun 1","Fukasaka M, Ori D, Kawagoe T, Uematsu S, Maruyama K, Okazaki T, Kozaki T, Imamura T, Tartey S, Mino T, Satoh T, Akira S, Takeuchi O"
< "Q9QYI5-3","21832061","Hsc70 protein interaction with soluble and fibrillar alpha-synuclein.","The Journal of biological chemistry","2011 Oct 7","Pemberton S, Madiona K, Pieri L, Kabani M, Bousset L, Melki R"
< "Q9QYI5-3","20395441","DNAJB2 expression in normal and diseased human and mouse skeletal muscle.","The American journal of pathology","2010 Jun","Claeys KG, Sozanska M, Martin JJ, Lacene E, Vignaud L, Stockholm D, Laforet P, Eymard B, Kichler A, Scherman D, Voit T, Israeli D"
< "Q9QYI5-3","16604191","Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.","The Journal of clinical investigation","2006 May","Borrell-Pages M, Canals JM, Cordelieres FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Neri C, Alberch J, Brouillet E, Saudou F, Humbert S"
---
> "Q8C2S5-1","29470856","Leishmania donovani inhibits ferroportin translation by modulating FBXL5-IRP2 axis for its growth within host macrophages.","Cellular microbiology","2018 Jul","Das NK, Sandhya S, G VV, Kumar R, Singh AK, Bal SK, Kumari S, Mukhopadhyay CK"
> "Q8C2S5-1","28714470","Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.","Nature communications","2017 Jul 17","Muto Y, Nishiyama M, Nita A, Moroishi T, Nakayama KI"
> "Q8C2S5-1","28069738","FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.","Molecular and cellular biology","2017 Apr 15","Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI"
> "Q8C2S5-1","24508277","F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen.","Journal of inorganic biochemistry","2014 Apr","Ruiz JC, Bruick RK"
> "Q9CUN6-1","12738770","E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation.","The Journal of biological chemistry","2003 Jul 25","Zhao M, Qiao M, Oyajobi BO, Mundy GR, Chen D"
> "Q9CUN6-1","10458166","A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation.","Nature","1999 Aug 12","Zhu H, Kavsak P, Abdollah S, Wrana JL, Thomsen GH"
1808a2009,2013
> "Q9WVS8-1","29723698","ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice.","Biochimica et biophysica acta. Molecular basis of disease","2018 Aug","Deng Y, Lei T, Li H, Mo X, Wang Z, Ou H"
> "Q9WVS8-1","29986870","The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.","Development (Cambridge, England)","2018 Jul 26","Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E"
> "Q9WVS8-1","29159830","ERK5 plays an essential role in gestational beta-cell proliferation.","Cell proliferation","2018 Jun","Chen C, Wu S, Lin X, Wu D, Fischbach S, Xiao X"
> "Q9WVS8-1","28887535","Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling.","Nature communications","2017 Sep 8","Liu W, Ruiz-Velasco A, Wang S, Khan S, Zi M, Jungmann A, Dolores Camacho-Munoz M, Guo J, Du G, Xie L, Oceandy D, Nicolaou A, Galli G, Muller OJ, Cartwright EJ, Ji Y, Wang X"
> "Q9WVS8-1","12093914","Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.","Proceedings of the National Academy of Sciences of the United States of America","2002 Jul 9","Regan CP, Li W, Boucher DM, Spatz S, Su MS, Kuida K"
1822a2028,2029
> "Q8VCQ6-1","30243987","Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.","Experimental neurology","2019 Jan","Lu MH, Ji WL, Xu DE, Yao PP, Zhao XY, Wang ZT, Fang LP, Huang R, Lan LJ, Chen JB, Wang TH, Cheng LH, Xu RX, Liu CF, Puglielli L, Ma QH"
> "Q8VCQ6-1","27892528","Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus.","Scientific reports","2016 Nov 28","Taniguchi M, Tasaki T, Ninomiya H, Ueda Y, Kuremoto KI, Mitsutake S, Igarashi Y, Okazaki T, Takegami T"
1837,1839d2043
< "Q3US41-1","29324788","Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis.","PloS one","2018","Saeidi S, Shapouri F, de Iongh RU, Casagranda F, Sutherland JM, Western PS, McLaughlin EA, Familari M, Hime GR"
< "Q3US41-1","29107558","ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.","Developmental cell","2017 Nov 6","Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ"
< "Q3US41-1","19285943","ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.","Molecular cell","2009 Mar 13","Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP"
1843a2048,2054
> "Q58A65-1","26320416","Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice.","FEBS letters","2015 Sep 14","Sato T, Ishikawa M, Yoshihara T, Nakazato R, Higashida H, Asano M, Yoshioka K"
> "Q9ESL4-1","27598200","A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.","Toxins","2016 Sep 2","Jandhyala DM, Wong J, Mantis NJ, Magun BE, Leong JM, Thorpe CM"
> "Q9ESL4-1","26755636","Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.","Genome research","2016 Feb","Spielmann M, Kakar N, Tayebi N, Leettola C, Nurnberg G, Sowada N, Lupianez DG, Harabula I, Flottmann R, Horn D, Chan WL, Wittler L, Yilmaz R, Altmuller J, Thiele H, van Bokhoven H, Schwartz CE, Nurnberg P, Bowie JU, Ahmad J, Kubisch C, Mundlos S, Borck G"
> "Q9ESL4-1","24789282","Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains.","PloS one","2014","Kobayashi M, Ohno T, Ihara K, Murai A, Kumazawa M, Hoshino H, Iwanaga K, Iwai H, Hamana Y, Ito M, Ohno K, Horio F"
> "Q9ESL4-1","15737997","Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA.","The Journal of biological chemistry","2005 May 13","Wang X, Mader MM, Toth JE, Yu X, Jin N, Campbell RM, Smallwood JK, Christe ME, Chatterjee A, Goodson T Jr, Vlahos CJ, Matter WF, Bloem LJ"
> "Q9ESL4-1","15684425","Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.","The Journal of biological chemistry","2005 Apr 8","Choi HS, Choi BY, Cho YY, Zhu F, Bode AM, Dong Z"
> "Q9ESL4-1","12761180","Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.","Journal of biochemistry","2003 Feb","Takahashi M, Gotoh Y, Isagawa T, Nishimura T, Goyama E, Kim HS, Mukai H, Ono Y"
1847c2058,2060
< "P63056-1","16115881","The Optimedin gene is a downstream target of Pax6.","The Journal of biological chemistry","2005 Oct 21","Grinchuk O, Kozmik Z, Wu X, Tomarev S"
---
> "A8Y5H7-1","15531584","The Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs.","The Journal of biological chemistry","2005 Jan 28","Kostenko EV, Mahon GM, Cheng L, Whitehead IP"
> "O54928-1","12242343","Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation.","Proceedings of the National Academy of Sciences of the United States of America","2002 Oct 1","Seki Y, Hayashi K, Matsumoto A, Seki N, Tsukada J, Ransom J, Naka T, Kishimoto T, Yoshimura A, Kubo M"
> "Q9JKD3-1","19240033","SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition.","The Journal of biological chemistry","2009 Apr 24","Noh JY, Lee H, Song S, Kim NS, Im W, Kim M, Seo H, Chung CW, Chang JW, Ferrante RJ, Yoo YJ, Ryu H, Jung YK"
1849d2061
< "O55047-1","28708136","Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.","Cell death and differentiation","2017 Nov","Segura-Bayona S, Knobel PA, Gonzalez-Buron H, Youssef SA, Pena-Blanco A, Coyaud E, Lopez-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH"
1864a2077,2078
> "Q80U04-1","27195677","praja2 regulates KSR1 stability and mitogenic signaling.","Cell death &amp; disease","2016 May 19","Rinaldi L, Delle Donne R, Sepe M, Porpora M, Garbi C, Chiuso F, Gallo A, Parisi S, Russo L, Bachmann V, Huber RG, Stefan E, Russo T, Feliciello A"
> "Q80U04-1","24561619","Role of the SIK2-p35-PJA2 complex in pancreatic beta-cell functional compensation.","Nature cell biology","2014 Mar","Sakamaki J, Fu A, Reeks C, Baird S, Depatie C, Al Azzabi M, Bardeesy N, Gingras AC, Yee SP, Screaton RA"
1866a2081
> "Q6ZPE2-1","11994405","Male infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1.","The Journal of clinical investigation","2002 May","Firestein R, Nagy PL, Daly M, Huie P, Conti M, Cleary ML"
1869d2083
< "Q9JIL6-1","15086536","The RAIG family member, GPRC5D, is associated with hard-keratinized structures.","The Journal of investigative dermatology","2004 Mar","Inoue S, Nambu T, Shimomura T"
1872a2087
> "Q8C167-1","23321636","Trans-Golgi network morphology and sorting is regulated by prolyl-oligopeptidase-like protein PREPL and the AP-1 complex subunit mu1A.","Journal of cell science","2013 Mar 1","Radhakrishnan K, Baltes J, Creemers JW, Schu P"
1875c2090
< "Q3U4H6-1","21807949","A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome.","Journal of cell science","2011 Aug 15","Keembiyehetty CN, Krzeslak A, Love DC, Hanover JA"
---
> "P97863-1","29965871","A novel long noncoding RNA lnc158 promotes the differentiation of mouse neural precursor cells into oligodendrocytes by targeting nuclear factor-IB.","Neuroreport","2018 Sep 5","Li Y, Guo B, Yang R, Xiao Z, Gao X, Yu J, Li S, Luo Y"
1879,1884d2093
< "Q8VIK5-1","29577896","Platelet endothelial aggregation receptor-1 (PEAR1) is involved in C2C12 myoblast differentiation.","Experimental cell research","2018 May 15","Cui YF, Yan YQ, Liu D, Pang YS, Wu J, Li SF, Tong HL"
< "Q8VIK5-1","26156496","Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.","Cardiovascular research","2015 Oct 1","Vandenbriele C, Kauskot A, Vandersmissen I, Criel M, Geenens R, Craps S, Luttun A, Janssens S, Hoylaerts MF, Verhamme P"
< "Q8VIK5-1","24743597","The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism.","Molecular biology of the cell","2014 Jun 15","Sullivan CS, Scheib JL, Ma Z, Dang RP, Schafer JM, Hickman FE, Brodsky FM, Ravichandran KS, Carter BD"
< "Q8VIK5-1","22993420","Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2012 Sep 19","Scheib JL, Sullivan CS, Carter BD"
< "Q8VIK5-1","19915564","Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.","Nature neuroscience","2009 Dec","Wu HH, Bellmunt E, Scheib JL, Venegas V, Burkert C, Reichardt LF, Zhou Z, Farinas I, Carter BD"
< "Q8VIK5-1","17226770","Jedi--a novel transmembrane protein expressed in early hematopoietic cells.","Journal of cellular biochemistry","2007 Jun 1","Krivtsov AV, Rozov FN, Zinovyeva MV, Hendrikx PJ, Jiang Y, Visser JW, Belyavsky AV"
1887a2097
> "Q6RFH4-1","15482850","Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells.","Molecular immunology","2004 Nov","Steinke JW, Hodsdon W, Parenti S, Ostraat R, Lutz R, Borish L, Hagman J"
1889,1890d2098
< "Q9CSU0-1","28893536","CREPT regulated by miR-138 promotes breast cancer progression.","Biochemical and biophysical research communications","2017 Nov 4","Liang Z, Feng Q, Xu L, Li S, Zhou L"
< "Q9CSU0-1","24982424","CREPT/RPRD1B, a recently identified novel protein highly expressed in tumors, enhances the beta-catenin.TCF4 transcriptional activity in response to Wnt signaling.","The Journal of biological chemistry","2014 Aug 15","Zhang Y, Liu C, Duan X, Ren F, Li S, Jin Z, Wang Y, Feng Y, Liu Z, Chang Z"
1891a2100
> "Q8BZL8-1","29609111","Regulation of anxiety-like behavior and Crhr1 expression in the basolateral amygdala by LMO3.","Psychoneuroendocrinology","2018 Jun","Savarese A, Lasek AW"
1904a2114,2115
> "P30999-1","29875160","A role for proteolytic regulation of delta-catenin in remodeling a subpopulation of dendritic spines in the rodent brain.","The Journal of biological chemistry","2018 Jul 20","Yuan L, Singh D, Buescher JL, Arikkath J"
> "P30999-1","29130932","p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia.","The Journal of clinical investigation","2017 Dec 1","Short SP, Kondo J, Smalley-Freed WG, Takeda H, Dohn MR, Powell AE, Carnahan RH, Washington MK, Tripathi M, Payne DM, Jenkins NA, Copeland NG, Coffey RJ, Reynolds AB"
1916,1918d2126
< "O54965-1","26197965","Enhanced metastasis in RNF13 knockout mice is mediated by a reduction in GM-CSF levels.","Protein &amp; cell","2015 Oct","Cheng H, Wang A, Meng J, Zhang Y, Zhu D"
< "O54965-1","24563216","Accelerated regeneration of the skeletal muscle in RNF13-knockout mice is mediated by macrophage-secreted IL-4/IL-6.","Protein &amp; cell","2014 Mar","Meng J, Zou X, Wu R, Zhong R, Zhu D, Zhang Y"
< "O54965-1","22890573","E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex.","Cellular and molecular life sciences : CMLS","2013 Jan","Zhang Q, Li Y, Zhang L, Yang N, Meng J, Zuo P, Zhang Y, Chen J, Wang L, Gao X, Zhu D"
1926a2135,2136
> "Q9WUD8-1","26866272","Loss of Fas apoptosis inhibitory molecule leads to spontaneous obesity and hepatosteatosis.","Cell death &amp; disease","2016 Feb 11","Huo J, Ma Y, Liu JJ, Ho YS, Liu S, Soh LY, Chen S, Xu S, Han W, Hong A, Lim SC, Lam KP"
> "Q61845-1","25248657","Characterization of membrane occupation and recognition nexus repeat containing 3, meiosis expressed gene 1 binding partner, in mouse male germ cells.","Asian journal of andrology","2015 Jan-Feb","Zhang L, Shang XJ, Li HF, Shi YQ, Li W, Teves ME, Wang ZQ, Jiang GF, Song SZ, Zhang ZB"
1928a2139,2142
> "Q6R0H7-1","30142336","GNAS(R201C) Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.","Gastroenterology","2018 Nov","Ideno N, Yamaguchi H, Ghosh B, Gupta S, Okumura T, Steffen DJ, Fisher CG, Wood LD, Singhi AD, Nakamura M, Gutkind JS, Maitra A"
> "Q6R0H7-1","15798190","Imprinted Nesp55 influences behavioral reactivity to novel environments.","Molecular and cellular biology","2005 Apr","Plagge A, Isles AR, Gordon E, Humby T, Dean W, Gritsch S, Fischer-Colbrie R, Wilkinson LS, Kelsey G"
> "Q6R0H7-1","15148396","XLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion Alex.","Proceedings of the National Academy of Sciences of the United States of America","2004 Jun 1","Abramowitz J, Grenet D, Birnbaumer M, Torres HN, Birnbaumer L"
> "Q6R0H7-1","10097123","A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2.","Proceedings of the National Academy of Sciences of the United States of America","1999 Mar 30","Peters J, Wroe SF, Wells CA, Miller HJ, Bodle D, Beechey CV, Williamson CM, Kelsey G"
1930a2145
> "Q99MR1-1","12771153","Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.","The Journal of biological chemistry","2003 Aug 22","Giovannone B, Lee E, Laviola L, Giorgino F, Cleveland KA, Smith RJ"
1934a2150
> "Q924Z6-1","22323606","Active maintenance of nuclear actin by importin 9 supports transcription.","Proceedings of the National Academy of Sciences of the United States of America","2012 Feb 28","Dopie J, Skarp KP, Rajakyla EK, Tanhuanpaa K, Vartiainen MK"
1939a2156,2157
> "Q9D842-1","27875275","Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.","Journal of cell science","2016 Dec 15","Syed KM, Joseph S, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR"
> "Q9D842-1","21211721","PARP-3 and APLF function together to accelerate nonhomologous end-joining.","Molecular cell","2011 Jan 7","Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW"
1950,1952d2167
< "Q91W10-1","28481222","Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.","The Journal of clinical investigation","2017 Jun 1","Lin W, Vann DR, Doulias PT, Wang T, Landesberg G, Li X, Ricciotti E, Scalia R, He M, Hand NJ, Rader DJ"
< "Q91W10-1","28057442","Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels.","Experimental eye research","2017 Feb","Sterling J, Guttha S, Song Y, Song D, Hadziahmetovic M, Dunaief JL"
< "Q91W10-1","17108009","Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.","American journal of physiology. Cell physiology","2007 Apr","Wang B, Schneider SN, Dragin N, Girijashanker K, Dalton TP, He L, Miller ML, Stringer KF, Soleimani M, Richardson DD, Nebert DW"
1955a2171,2175
> "Q9Z1X4-1","28487382","NF45 and NF90/NF110 coordinately regulate ESC pluripotency and differentiation.","RNA (New York, N.Y.)","2017 Aug","Ye J, Jin H, Pankov A, Song JS, Blelloch R"
> "Q9Z1X4-1","26289635","Nanog RNA-binding proteins YBX1 and ILF3 affect pluripotency of embryonic stem cells.","Cell biology international","2016 Aug","Guo C, Xue Y, Yang G, Yin S, Shi W, Cheng Y, Yan X, Fan S, Zhang H, Zeng F"
> "Q9Z1X4-1","25918244","Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers.","Molecular and cellular biology","2015 Jul","Todaka H, Higuchi T, Yagyu K, Sugiyama Y, Yamaguchi F, Morisawa K, Ono M, Fukushima A, Tsuda M, Taniguchi T, Sakamoto S"
> "Q9Z1X4-1","11438536","Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR.","The Journal of biological chemistry","2001 Aug 24","Saunders LR, Perkins DJ, Balachandran S, Michaels R, Ford R, Mayeda A, Barber GN"
> "Q9Z1X4-1","7519613","Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.","The Journal of biological chemistry","1994 Aug 12","Kao PN, Chen L, Brock G, Ng J, Kenny J, Smith AJ, Corthesy B"
1962,1965c2182,2183
< "Q03146-1","29298894","Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.","The Journal of biological chemistry","2018 Feb 23","Sun X, Gupta K, Wu B, Zhang D, Yuan B, Zhang X, Chiang HC, Zhang C, Curiel TJ, Bendeck MP, Hursting S, Hu Y, Li R"
< "Q03146-1","29483153","Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers.","Genes &amp; development","2018 Feb 1","Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z"
< "Q03146-1","27915093","Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis.","Matrix biology : journal of the International Society for Matrix Biology","2017 Jan","Borza CM, Su Y, Tran TL, Yu L, Steyns N, Temple KJ, Skwark MJ, Meiler J, Lindsley CW, Hicks BR, Leitinger B, Zent R, Pozzi A"
< "Q8BKC8-1","23541637","Aldosterone-induced ENaC and basal Na+/K+-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIIIbeta trans Golgi signalling in M1 cortical collecting duct cells.","Molecular and cellular endocrinology","2013 Jun 15","Dooley R, Angibaud E, Yusef YR, Thomas W, Harvey BJ"
---
> "P35545-1","30710197","Heat shock protein 60 negatively regulates the biological functions of ubiquitin-like protein MNSFbeta in macrophages.","Molecular and cellular biochemistry","2019 Jun","Nakamura M, Notsu K, Nakagawa M"
> "Q8C031-1","17785411","Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments.","Proceedings of the National Academy of Sciences of the United States of America","2007 Sep 11","Nishimura-Akiyoshi S, Niimi K, Nakashiba T, Itohara S"
1967c2185,2195
< "Q8R4V1-1","15143214","NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.","Proceedings of the National Academy of Sciences of the United States of America","2004 May 25","Ohtsuka M, Arase H, Takeuchi A, Yamasaki S, Shiina R, Suenaga T, Sakurai D, Yokosuka T, Arase N, Iwashima M, Kitamura T, Moriya H, Saito T"
---
> "Q8R2Y0-1","27783937","alpha/beta-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility.","Cell reports","2016 Oct 25","Fisette A, Tobin S, Decarie-Spain L, Bouyakdan K, Peyot ML, Madiraju SRM, Prentki M, Fulton S, Alquier T"
> "Q8R2Y0-1","26997277","alpha/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes.","Cell reports","2016 Mar 29","Zhao S, Mugabo Y, Ballentine G, Attane C, Iglesias J, Poursharifi P, Zhang D, Nguyen TA, Erb H, Prentki R, Peyot ML, Joly E, Tobin S, Fulton S, Brown JM, Madiraju SR, Prentki M"
> "Q8R2Y0-1","23806692","Fatty acid amide hydrolase but not monoacyl glycerol lipase controls cell death induced by the endocannabinoid 2-arachidonoyl glycerol in hepatic cell populations.","Biochemical and biophysical research communications","2013 Jul 19","Siegmund SV, Wojtalla A, Schlosser M, Zimmer A, Singer MV"
> "Q8R2Y0-1","21665953","Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons.","The Journal of biological chemistry","2011 Aug 19","Marrs WR, Horne EA, Ortega-Gutierrez S, Cisneros JA, Xu C, Lin YH, Muccioli GG, Lopez-Rodriguez ML, Stella N"
> "Q8R2Y0-1","20657592","The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.","Nature neuroscience","2010 Aug","Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, Xu C, Moller T, Mackie K, Manzoni OJ, Cravatt BF, Stella N"
> "Q8R2Y0-1","18096503","A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.","Chemistry &amp; biology","2007 Dec","Blankman JL, Simon GM, Cravatt BF"
> "Q8K445-1","26943149","Impairment of Vision in a Mouse Model of Usher Syndrome Type III.","Investigative ophthalmology &amp; visual science","2016 Mar","Tian G, Lee R, Ropelewski P, Imanishi Y"
> "Q8K445-1","19414487","Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation.","Human molecular genetics","2009 Aug 1","Geng R, Geller SF, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Jones SM, Wright CG, Melki S, Imanishi Y, Palczewski K, Alagramam KN, Flannery JG"
> "Q8K445-1","19423712","Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeleton.","The Journal of biological chemistry","2009 Jul 10","Tian G, Zhou Y, Hajkova D, Miyagi M, Dinculescu A, Hauswirth WW, Palczewski K, Geng R, Alagramam KN, Isosomppi J, Sankila EM, Flannery JG, Imanishi Y"
> "Q8K445-1","17493778","Anti-clarin-1 AAV-delivered ribozyme induced apoptosis in the mouse cochlea.","Hearing research","2007 Aug","Aarnisalo AA, Pietola L, Joensuu J, Isosomppi J, Aarnisalo P, Dinculescu A, Lewin AS, Flannery J, Hauswirth WW, Sankila EM, Jero J"
> "Q8K445-1","12080385","USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses.","European journal of human genetics : EJHG","2002 Jun","Adato A, Vreugde S, Joensuu T, Avidan N, Hamalainen R, Belenkiy O, Olender T, Bonne-Tamir B, Ben-Asher E, Espinos C, Millan JM, Lehesjoki AE, Flannery JG, Avraham KB, Pietrokovski S, Sankila EM, Beckmann JS, Lancet D"
1968a2197
> "Q8BZM0-1","18303015","BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase.","The Journal of biological chemistry","2008 Apr 25","Rondou P, Haegeman G, Vanhoenacker P, Van Craenenbroeck K"
1969a2199
> "Q9WUM3-1","25995115","Single-molecule imaging of a three-component ordered actin disassembly mechanism.","Nature communications","2015 May 21","Jansen S, Collins A, Chin SM, Ydenberg CA, Gelles J, Goode BL"
1974a2205,2209
> "Q8BWY7-1","23643525","Characterization of the GufA subfamily member SLC39A11/Zip11 as a zinc transporter.","The Journal of nutritional biochemistry","2013 Oct","Yu Y, Wu A, Zhang Z, Yan G, Zhang F, Zhang L, Shen X, Hu R, Zhang Y, Zhang K, Wang F"
> "Q3ULA2-1","30031111","beta-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.","Biochimica et biophysica acta. General subjects","2018 Oct","Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K"
> "Q61147-1","30060949","Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.","Biochemical and biophysical research communications","2018 Sep 10","Xu E, Chen M, Zheng J, Maimaitiming Z, Zhong T, Chen H"
> "Q61147-1","30182051","Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin.","Cellular and molecular gastroenterology and hepatology","2018","Fuqua BK, Lu Y, Frazer DM, Darshan D, Wilkins SJ, Dunn L, Loguinov AV, Kogan SC, Matak P, Chen H, Dunaief JL, Vulpe CD, Anderson GJ"
> "Q8CGB3-1","15271982","Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis.","The Journal of biological chemistry","2004 Sep 24","Sakai T, Liu L, Teng X, Mukai-Sakai R, Shimada H, Kaji R, Mitani T, Matsumoto M, Toida K, Ishimura K, Shishido Y, Mak TW, Fukui K"
1984a2220
> "Q8BG93-1","12767940","Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides.","Biochemical and biophysical research communications","2003 Jun 13","Cai JP, Ishibashi T, Takagi Y, Hayakawa H, Sekiguchi M"
1985a2222
> "O70291-1","27045027","Gastrorenal Axis.","Hypertension (Dallas, Tex. : 1979)","2016 Jun","Jose PA, Felder RA, Yang Z, Zeng C, Eisner GM"
1992,1994d2228
< "Q3UZ39-1","24690174","Higher LRRFIP1 expression in glioblastoma multiforme is associated with better response to teniposide, a type II topoisomerase inhibitor.","Biochemical and biophysical research communications","2014 Apr 18","Li WQ, Yu HY, Li YM, Wang X, He J, Yan HZ, Yang DH, Wu XJ, Hou LJ, Liu HM, Xia CY, Lu YC"
< "Q3UZ39-1","20586614","Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response.","Journal of interferon &amp; cytokine research : the official journal of the International Society for Interferon and Cytokine Research","2010 Nov","Bagashev A, Fitzgerald MC, Larosa DF, Rose PP, Cherry S, Johnson AC, Sullivan KE"
< "Q3UZ39-1","20453844","The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway.","Nature immunology","2010 Jun","Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X"
2000,2005d2233
< "Q3URR7-1","28846095","ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors.","Nature cell biology","2017 Sep","Skamagki M, Correia C, Yeung P, Baslan T, Beck S, Zhang C, Ross CA, Dang L, Liu Z, Giunta S, Chang TP, Wang J, Ananthanarayanan A, Bohndorf M, Bosbach B, Adjaye J, Funabiki H, Kim J, Lowe S, Collins JJ, Lu CW, Li H, Zhao R, Kim K"
< "Q3URR7-1","26592664","Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells.","Biochemical and biophysical research communications","2015 Dec 25","Yamane M, Fujii S, Ohtsuka S, Niwa H"
< "Q3URR7-1","25111779","Pleiotropic functions for transcription factor zscan10.","PloS one","2014","Kraus P, V S, Yu HB, Xing X, Lim SL, Adler T, Pimentel JA, Becker L, Bohla A, Garrett L, Hans W, Holter SM, Janas E, Moreth K, Prehn C, Puk O, Rathkolb B, Rozman J, Adamski J, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Neff F, Ollert M, Stoeger T, Yildrim AO, Eickelberg O, Wolf E, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Lufkin T, Stanton LW"
< "Q3URR7-1","22505416","Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206.","Acta crystallographica. Section F, Structural biology and crystallization communications","2012 Apr 1","Liang Y, Choo SH, Rossbach M, Baburajendran N, Palasingam P, Kolatkar PR"
< "Q3URR7-1","17628018","Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells.","Stem cells (Dayton, Ohio)","2007 Sep","Wang ZX, Kueh JL, Teh CH, Rossbach M, Lim L, Li P, Wong KY, Lufkin T, Robson P, Stanton LW"
< "Q3URR7-1","16971461","Zfp206 regulates ES cell gene expression and differentiation.","Nucleic acids research","2006","Zhang W, Walker E, Tamplin OJ, Rossant J, Stanford WL, Hughes TR"
2011,2013c2239,2241
< "Q9DC40-1","24657168","Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.","Molecular cell","2014 Apr 10","Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH"
< "Q9DC40-1","20864032","CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.","Molecular cell","2010 Sep 24","Horejsi Z, Takai H, Adelman CA, Collis SJ, Flynn H, Maslen S, Skehel JM, de Lange T, Boulton SJ"
< "Q9DC40-1","18160036","Tel2 regulates the stability of PI3K-related protein kinases.","Cell","2007 Dec 28","Takai H, Wang RC, Takai KK, Yang H, de Lange T"
---
> "Q9WV02-1","19403048","SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.","BMB reports","2009 Apr 30","Omura Y, Nishio Y, Takemoto T, Ikeuchi C, Sekine O, Morino K, Maeno Y, Obata T, Ugi S, Maegawa H, Kimura H, Kashiwagi A"
> "Q9WV02-1","17188681","RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet.","FEBS letters","2007 Jan 23","Takemoto T, Nishio Y, Sekine O, Ikeuchi C, Nagai Y, Maeno Y, Maegawa H, Kimura H, Kashiwagi A"
> "O88673-1","27697466","Diacylglycerol kinases in cancer.","Advances in biological regulation","2017 Jan","Merida I, Torres-Ayuso P, Avila-Flores A, Arranz-Nicolas J, Andrada E, Tello-Lafoz M, Liebana R, Arcos R"
2022,2024c2250
< "O88904-1","22095214","Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1.","Cerebral cortex (New York, N.Y. : 1991)","2012 Oct","Marinaro C, Pannese M, Weinandy F, Sessa A, Bergamaschi A, Taketo MM, Broccoli V, Comi G, Gotz M, Martino G, Muzio L"
< "O88904-1","22545114","Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response.","PloS one","2012","Guerra FM, Gommerman JL, Corfe SA, Paige CJ, Rottapel R"
< "O88904-1","12529400","Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.","Molecular and cellular biology","2003 Feb","Ecsedy JA, Michaelson JS, Leder P"
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> "Q64329-1","30381460","Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer.","Proceedings of the National Academy of Sciences of the United States of America","2018 Nov 13","Shi L, Li K, Guo Y, Banerjee A, Wang Q, Lorenz UM, Parlak M, Sullivan LC, Onyema OO, Arefanian S, Stelow EB, Brautigan DL, Bullock TNJ, Brown MG, Krupnick AS"
2025a2252,2256
> "Q9D2H6-1","30337366","Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites.","The Journal of biological chemistry","2018 Dec 14","Volkel S, Stielow B, Finkernagel F, Berger D, Stiewe T, Nist A, Suske G"
> "Q9D2H6-1","27191968","Transcription Factor SP2 Enhanced the Expression of Cd14 in Colitis-Susceptible C3H/HeJBir.","PloS one","2016","Zschemisch NH, Brusch I, Hambusch AS, Bleich A"
> "Q9D2H6-1","25793500","Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3.","PLoS genetics","2015 Mar","Volkel S, Stielow B, Finkernagel F, Stiewe T, Nist A, Suske G"
> "Q9D2H6-1","23293287","Neural development is dependent on the function of specificity protein 2 in cell cycle progression.","Development (Cambridge, England)","2013 Feb 1","Liang H, Xiao G, Yin H, Hippenmeyer S, Horowitz JM, Ghashghaei HT"
> "Q91X83-1","29749642","A novel mechanism of the M1-M2 methionine adenosyltransferase switch-mediated hepatocellular carcinoma metastasis.","Molecular carcinogenesis","2018 Sep","Wang R, Jin Y, Yao XH, Fan W, Zhang J, Cao Y, Li J"
2027a2259,2260
> "Q921N8-1","29499132","Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation.","Molecular cell","2018 Mar 1","Cardamone MD, Tanasa B, Cederquist CT, Huang J, Mahdaviani K, Li W, Rosenfeld MG, Liesa M, Perissi V"
> "Q921N8-1","20159957","GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.","Genes &amp; development","2010 Feb 15","Venteclef N, Jakobsson T, Ehrlund A, Damdimopoulos A, Mikkonen L, Ellis E, Nilsson LM, Parini P, Janne OA, Gustafsson JA, Steffensen KR, Treuter E"
2037,2041d2269
< "Q8BUE4-1","28732772","A brain-specific isoform of apoptosis-inducing factor 2 attenuates ischemia-induced oxidative stress in HT22 cells.","Neurochemistry international","2018 Jan","Xie Y, Wanggou S, Liu Q, Li X, Liu J, Wu M"
< "Q8BUE4-1","26689472","Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling.","Free radical biology &amp; medicine","2016 Feb","Miriyala S, Thippakorn C, Chaiswing L, Xu Y, Noel T, Tovmasyan A, Batinic-Haberle I, Vander Kooi CW, Chi W, Latif AA, Panchatcharam M, Prachayasittikul V, Butterfield DA, Vore M, Moscow J, St Clair DK"
< "Q8BUE4-1","26168492","Apoptosis-inducing Factor, Mitochondrion-associated 2, Regulates Klf1 in a Mouse Erythroleukemia Cell Line.","Anticancer research","2015 Aug","Kojima N, Tanaka Y, Kulkeaw K, Nakanishi Y, Shirasawa S, Sugiyama D"
< "Q8BUE4-1","21366272","Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase.","Biochemistry","2011 Apr 12","Zhou Y, Feng X, Koh DW"
< "Q8BUE4-1","16186796","The p53-inducible apoptotic protein AMID is not required for normal development and tumor suppression.","Oncogene","2006 Feb 9","Mei J, Webb S, Zhang B, Shu HB"
2043a2272,2274
> "Q8C5N3-1","28250049","Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22.","Disease models &amp; mechanisms","2017 Mar 1","Kobayashi M, Chandrasekhar A, Cheng C, Martinez JA, Ng H, de la Hoz C, Zochodne DW"
> "Q8C5N3-1","27371833","The Evolutionary Fates of a Large Segmental Duplication in Mouse.","Genetics","2016 Sep","Morgan AP, Holt JM, McMullan RC, Bell TA, Clayshulte AM, Didion JP, Yadgary L, Thybert D, Odom DT, Flicek P, McMillan L, de Villena FP"
> "Q8C5N3-1","26149421","Divergence patterns of genic copy number variation in natural populations of the house mouse (Mus musculus domesticus) reveal three conserved genes with major population-specific expansions.","Genome research","2015 Aug","Pezer Z, Harr B, Teschke M, Babiker H, Tautz D"
2048,2050c2279
< "Q501J6-1","29431742","Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA.","Nature medicine","2018 Mar","Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P"
< "Q501J6-1","26947125","The loop structure and the RNA helicase p72/DDX17 influence the processing efficiency of the mice miR-132.","Scientific reports","2016 Mar 7","Remenyi J, Bajan S, Fuller-Pace FV, Arthur JS, Hutvagner G"
< "Q501J6-1","22266867","Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.","Oncogene","2012 Oct 18","Germann S, Gratadou L, Zonta E, Dardenne E, Gaudineau B, Fougere M, Samaan S, Dutertre M, Jauliac S, Auboeuf D"
---
> "Q8C7M3-1","28701345","TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.","Molecular biology of the cell","2017 Sep 1","Plooster M, Menon S, Winkle CC, Urbina FL, Monkiewicz C, Phend KD, Weinberg RJ, Gupton SL"
2056a2286,2288
> "Q9R0N7-1","29957297","Synaptotagmin-7 controls the size of the reserve and resting pools of synaptic vesicles in hippocampal neurons.","Cell calcium","2018 Sep","Duran E, Montes MA, Jemal I, Satterfield R, Young S, Alvarez de Toledo G"
> "Q9R0N7-1","29771357","A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.","Human molecular genetics","2018 Aug 15","Barzilai-Tutsch H, Dewulf M, Lamaze C, Butler Browne G, Pines M, Halevy O"
> "Q9R0N7-1","12071850","Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human.","The Biochemical journal","2002 Jul 1","Fukuda M, Ogata Y, Saegusa C, Kanno E, Mikoshiba K"
2061a2294
> "Q0GGX2-1","18849567","A novel germ cell-specific protein, SHIP1, forms a complex with chromatin remodeling activity during spermatogenesis.","The Journal of biological chemistry","2008 Dec 12","Choi E, Han C, Park I, Lee B, Jin S, Choi H, Kim DH, Park ZY, Eddy EM, Cho C"
2062a2296,2299
> "A6PWY4-1","30655611","WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.","Nature communications","2019 Jan 17","Jeong WJ, Park JC, Kim WS, Ro EJ, Jeon SH, Lee SK, Park YN, Min DS, Choi KY"
> "Q8BTW9-1","12529371","p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death.","The Journal of biological chemistry","2003 Mar 21","Lu Y, Pan ZZ, Devaux Y, Ray P"
> "O70589-1","28234597","Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice.","Journal of psychiatry &amp; neuroscience : JPN","2017 Jan","Huang TN, Hsueh YP"
> "O70589-1","27036546","X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner.","Acta neuropathologica communications","2016 Mar 31","Srivastava S, McMillan R, Willis J, Clark H, Chavan V, Liang C, Zhang H, Hulver M, Mukherjee K"
2064,2067d2300
< "O54785-1","28669900","Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain.","Neuropharmacology","2017 Oct","Yang X, He G, Zhang X, Chen L, Kong Y, Xie W, Jia Z, Liu WT, Zhou Z"
< "Q9JHG6-1","30442942","Conditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture.","Nature communications","2018 Nov 15","Villahoz S, Yunes-Leites PS, Mendez-Barbero N, Urso K, Bonzon-Kulichenko E, Ortega S, Nistal JF, Vazquez J, Offermanns S, Redondo JM, Campanero MR"
< "Q9JHG6-1","30139658","RCAN1 is a marker of oxidative stress, induced in acute pancreatitis.","Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]","2018 Oct","Norberg KJ, Nania S, Li X, Gao H, Szatmary P, Segersvard R, Haas S, Wagman A, Arnelo U, Sutton R, Heuchel RL, Lohr JM"
< "Q9JHG6-1","29799862","Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways.","PloS one","2018","Pang Z, Junkins RD, Raudonis R, MacNeil AJ, McCormick C, Cheng Z, Lin TJ"
2069,2070d2301
< "Q61730-1","25449578","The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice.","Brain, behavior, and immunity","2015 Jul","Davis CJ, Dunbrasky D, Oonk M, Taishi P, Opp MR, Krueger JM"
< "Q61730-1","25908590","Mechanisms of splicing-dependent trans-synaptic adhesion by PTPdelta-IL1RAPL1/IL-1RAcP for synaptic differentiation.","Nature communications","2015 Apr 24","Yamagata A, Yoshida T, Sato Y, Goto-Ito S, Uemura T, Maeda A, Shiroshima T, Iwasawa-Okamoto S, Mori H, Mishina M, Fukai S"
2073a2305,2306
> "Q9QYR6-1","28701415","Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain.","The Biochemical journal","2017 Aug 10","Xia Y, Shang Y, Zhang R, Zhu J"
> "Q9QYR6-1","26609151","Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Nov 25","Takei Y, Kikkawa YS, Atapour N, Hensch TK, Hirokawa N"
2081a2315
> "Q8BGT1-1","16872596","Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.","Developmental biology","2006 Sep 1","Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW"
2088,2090d2321
< "Q61210-1","29130930","Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.","The Journal of clinical investigation","2017 Dec 1","Carbone ML, Chadeuf G, Heurtebise-Chretien S, Prieur X, Quillard T, Goueffic Y, Vaillant N, Rio M, Castan L, Durand M, Baron-Menguy C, Aureille J, Desfrancois J, Tesse A, Torres RM, Loirand G"
< "Q61210-1","27923664","Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons.","Neuroscience letters","2017 Jan 18","Xiang X, Zhuang X, Li S, Shi L"
< "Q61210-1","27489999","Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.","FEBS letters","2016 Sep","Xiang X, Li S, Zhuang X, Shi L"
2098,2100d2328
< "Q99MK9-1","29382819","RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.","Nature communications","2018 Jan 30","Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E"
< "Q99MK9-1","27765918","beta-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients.","Oncotarget","2016 Oct 18","Schirosi L, Mazzotta A, Opinto G, Pinto R, Graziano G, Tommasi S, Fucci L, Simone G, Mangia A"
< "Q99MK9-1","15665283","Tumor susceptibility of Rassf1a knockout mice.","Cancer research","2005 Jan 1","Tommasi S, Dammann R, Zhang Z, Wang Y, Liu L, Tsark WM, Wilczynski SP, Li J, You M, Pfeifer GP"
2104a2333,2334
> "Q8VDF2-1","31024001","UHRF genes regulate programmed interdigital tissue regression and chondrogenesis in the embryonic limb.","Cell death &amp; disease","2019 Apr 25","Sanchez-Fernandez C, Lorda-Diez CI, Garcia-Porrero JA, Montero JA, Hurle JM"
> "Q8VDF2-1","29968706","Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.","Nature communications","2018 Jul 3","Kim KY, Tanaka Y, Su J, Cakir B, Xiang Y, Patterson B, Ding J, Jung YW, Kim JH, Hysolli E, Lee H, Dajani R, Kim J, Zhong M, Lee JH, Skalnik D, Lim JM, Sullivan GJ, Wang J, Park IH"
2112,2115d2341
< "Q9QYY8-1","30213879","Functional differences of short and long isoforms of spastin harboring missense mutation.","Disease models &amp; mechanisms","2018 Sep 10","Plaud C, Joshi V, Kajevu N, Pous C, Curmi PA, Burgo A"
< "Q9QYY8-1","28392418","Spastin regulates VAMP7-containing vesicles trafficking in cortical neurons.","Biochimica et biophysica acta. Molecular basis of disease","2017 Jun","Plaud C, Joshi V, Marinello M, Pastre D, Galli T, Curmi PA, Burgo A"
< "Q9QYY8-1","27773584","Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination.","Neuron","2016 Nov 23","Brill MS, Kleele T, Ruschkies L, Wang M, Marahori NA, Reuter MS, Hausrat TJ, Weigand E, Fisher M, Ahles A, Engelhardt S, Bishop DL, Kneussel M, Misgeld T"
< "Q9QYY8-1","24065130","Amyloid-beta oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.","The EMBO journal","2013 Nov 13","Zempel H, Luedtke J, Kumar Y, Biernat J, Dawson H, Mandelkow E, Mandelkow EM"
2148,2158c2374,2382
< "Q7TNT2-1","30372477","Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia.","PloS one","2018","Sundberg JP, Shen T, Fiehn O, Rice RH, Silva KA, Kennedy VE, Gott NE, Dionne LA, Bechtold LS, Murray SA, Kuiper R, Pratt CH"
< "Q7TNT2-1","24009241","Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene.","Journal of the American Society of Nephrology : JASN","2013 Dec","Noordmans GA, Caputo CR, Huang Y, Sheehan SM, Bulthuis M, Heeringa P, Hillebrands JL, van Goor H, Korstanje R"
< "Q7TNT2-1","15220349","Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.","The Journal of biological chemistry","2004 Sep 3","Cheng JB, Russell DW"
< "Q7TNT2-1","15220348","Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.","The Journal of biological chemistry","2004 Sep 3","Cheng JB, Russell DW"
< "Q8CI15-1","29673590","The cross roles of sphingosine kinase 1/2 and ceramide glucosyltransferase in cell growth and death.","Biochemical and biophysical research communications","2018 Jun 7","Qin J, Kilkus JP, Dawson G"
< "Q8CI15-1","17643421","Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway.","Experimental cell research","2007 Sep 10","Soldi R, Mandinova A, Venkataraman K, Hla T, Vadas M, Pitson S, Duarte M, Graziani I, Kolev V, Kacer D, Kirov A, Maciag T, Prudovsky I"
< "Q8CI15-1","16623665","Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.","The Biochemical journal","2006 Aug 1","Venkataraman K, Thangada S, Michaud J, Oo ML, Ai Y, Lee YM, Wu M, Parikh NS, Khan F, Proia RL, Hla T"
< "Q8CI15-1","16368679","Mouse sphingosine kinase isoforms SPHK1a and SPHK1b differ in enzymatic traits including stability, localization, modification, and oligomerization.","The Journal of biological chemistry","2006 Feb 17","Kihara A, Anada Y, Igarashi Y"
< "Q8CI15-1","12391145","Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases.","Molecular and cellular biology","2002 Nov","Shu X, Wu W, Mosteller RD, Broek D"
< "P19973-1","27555448","Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells.","Nature communications","2016 Aug 24","Wu JL, Wu HY, Tsai DY, Chiang MF, Chen YJ, Gao S, Lin CC, Lin CH, Khoo KH, Chen YJ, Lin KI"
< "P19973-1","26554018","Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis.","Proceedings of the National Academy of Sciences of the United States of America","2015 Nov 24","Hwang SH, Jung SH, Lee S, Choi S, Yoo SA, Park JH, Hwang D, Shim SC, Sabbagh L, Kim KJ, Park SH, Cho CS, Kim BS, Leng L, Montgomery RR, Bucala R, Chung YJ, Kim WU"
---
> "Q2Q5T5-1","29581287","Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration.","Proceedings of the National Academy of Sciences of the United States of America","2018 Apr 10","Bi P, McAnally JR, Shelton JM, Sanchez-Ortiz E, Bassel-Duby R, Olson EN"
> "Q2Q5T5-1","28569755","Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development.","Nature communications","2017 Jun 1","Quinn ME, Goh Q, Kurosaka M, Gamage DG, Petrany MJ, Prasad V, Millay DP"
> "Q2Q5T5-1","28569745","The microprotein Minion controls cell fusion and muscle formation.","Nature communications","2017 Jun 1","Zhang Q, Vashisht AA, O'Rourke J, Corbel SY, Moran R, Romero A, Miraglia L, Zhang J, Durrant E, Schmedt C, Sampath SC, Sampath SC"
> "Q2Q5T5-1","28386024","Control of muscle formation by the fusogenic micropeptide myomixer.","Science (New York, N.Y.)","2017 Apr 21","Bi P, Ramirez-Martinez A, Li H, Cannavino J, McAnally JR, Shelton JM, Sanchez-Ortiz E, Bassel-Duby R, Olson EN"
> "Q2Q5T5-1","28637957","Gm7325 is MyoD-dependently expressed in activated muscle satellite cells.","Biomedical research (Tokyo, Japan)","2017","Takei D, Nishi M, Fukada S, Doi M, Okamura H, Uezumi A, Zhang L, Yoshida M, Miyazato M, Ichimura A, Takeshima H"
> "Q2Q5T5-1","16331322","Molecular cloning and functional analysis of ESGP, an embryonic stem cell and germ cell specific protein.","Acta biochimica et biophysica Sinica","2005 Dec","Chen YM, Du ZW, Yao Z"
> "Q62393-1","28798933","Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.","BioMed research international","2017","Ito C, Mukudai Y, Itose M, Kato K, Motohashi H, Shimane T, Kondo S, Shirota T"
> "Q62393-1","26183179","TPD52 expression increases neutral lipid storage within cultured cells.","Journal of cell science","2015 Sep 1","Kamili A, Roslan N, Frost S, Cantrill LC, Wang D, Della-Franca A, Bright RK, Groblewski GE, Straub BK, Hoy AJ, Chen Y, Byrne JA"
> "Q62393-1","17314271","Induction of tumorigenesis and metastasis by the murine orthologue of tumor protein D52.","Molecular cancer research : MCR","2007 Feb","Lewis JD, Payton LA, Whitford JG, Byrne JA, Smith DI, Yang L, Bright RK"
2165,2166c2389
< "Q925H0-1","30074209","Identification and Function of Acid-sensing Ion Channels in RAW 264.7 Macrophage Cells.","Current medical science","2018 Jun","Ni L, Fang P, Hu ZL, Zhou HY, Chen JG, Wang F, Jin Y"
< "Q925H0-1","27402850","Modulation of Acid-sensing Ion Channel 1a by Intracellular pH and Its Role in Ischemic Stroke.","The Journal of biological chemistry","2016 Aug 26","Li MH, Leng TD, Feng XC, Yang T, Simon RP, Xiong ZG"
---
> "P20029-1","30573681","Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells.","The Journal of biological chemistry","2019 Feb 15","Ogawa S, Matsuoka Y, Takada M, Matsui K, Yamane F, Kubota E, Yasuhara S, Hieda K, Kanayama N, Hatano N, Tokumitsu H, Magari M"
2168d2390
< "P26618-1","27894125","Intronic polyadenylation of PDGFRalpha in resident stem cells attenuates muscle fibrosis.","Nature","2016 Dec 8","Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA"
2172,2178c2394,2395
< "Q7TSD4-1","24361585","Spatial gene's (Tbata) implication in neurite outgrowth and dendrite patterning in hippocampal neurons.","Molecular and cellular neurosciences","2014 Mar","Yammine M, Saade M, Chauvet S, Nguyen C"
< "Q7TSD4-1","20937703","Tbata modulates thymic stromal cell proliferation and thymus function.","The Journal of experimental medicine","2010 Oct 25","Flomerfelt FA, El Kassar N, Gurunathan C, Chua KS, League SC, Schmitz S, Gershon TR, Kapoor V, Yan XY, Schwartz RH, Gress RE"
< "Q7TSD4-1","19918778","Spatial (Tbata) expression in mature medullary thymic epithelial cells.","European journal of immunology","2010 Feb","Saade M, Irla M, Yammine M, Boulanger N, Victorero G, Vincentelli R, Penninger JM, Hollander GA, Chauvet S, Nguyen C"
< "Q7TSD4-1","17961552","Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17.","Experimental cell research","2007 Dec 10","Irla M, Saade M, Fernandez C, Chasson L, Victorero G, Dahmane N, Chazal G, Nguyen C"
< "Q7TSD4-1","17196196","Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b.","Experimental cell research","2007 Feb 1","Saade M, Irla M, Govin J, Victorero G, Samson M, Nguyen C"
< "Q7TSD4-1","15236666","Genomic organization and the tissue distribution of alternatively spliced isoforms of the mouse Spatial gene.","BMC genomics","2004 Jul 5","Irla M, Puthier D, Granjeaud S, Saade M, Victorero G, Mattei MG, Nguyen C"
< "Q7TSD4-1","11196687","Spatial, a gene expressed in thymic stromal cells, depends on three-dimensional thymus organization for its expression.","Genes and immunity","2000 Aug","Flomerfelt FA, Kim MG, Schwartz RH"
---
> "Q91WE1-1","26115702","SNX15 Regulates Cell Surface Recycling of APP and Abeta Generation.","Molecular neurobiology","2016 Aug","Feng T, Niu M, Ji C, Gao Y, Wen J, Bu G, Xu H, Zhang YW"
> "P42230-1","30662340","Lipopolysaccharide promoted proliferation and adipogenesis of preadipocytes through JAK/STAT and AMPK-regulated cPLA2 expression.","International journal of medical sciences","2019","Chang CC, Sia KC, Chang JF, Lin CM, Yang CM, Huang KY, Lin WN"
2181,2185c2398
< "Q14BU0-1","29720262","Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis.","Arthritis research &amp; therapy","2018 May 2","Seuffert F, Weidner D, Baum W, Schett G, Stock M"
< "Q14BU0-1","24867294","Insights into the association of Gla-rich protein and osteoarthritis, novel splice variants and gamma-carboxylation status.","Molecular nutrition &amp; food research","2014 Aug","Rafael MS, Cavaco S, Viegas CS, Santos S, Ramos A, Willems BA, Herfs M, Theuwissen E, Vermeer C, Simes DC"
< "Q14BU0-1","19819238","Identification of four alternatively spliced transcripts of the Ucma/GRP gene, encoding a new Gla-containing protein.","Experimental cell research","2010 Jan 15","Le Jeune M, Tomavo N, Tian TV, Flourens A, Marchand N, Camuzeaux B, Mallein-Gerin F, Duterque-Coquillaud M"
< "Q14BU0-1","18156182","Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis.","The Journal of biological chemistry","2008 Mar 14","Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J, Tagariello A, Onnerfjord P, Heinegard D, Schlotzer-Schrehardt U, Deutzmann R, von der Mark K, Stock M"
< "Q14BU0-1","17707622","Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes.","Matrix biology : journal of the International Society for Matrix Biology","2008 Jan","Tagariello A, Luther J, Streiter M, Didt-Koziel L, Wuelling M, Surmann-Schmitt C, Stock M, Adam N, Vortkamp A, Winterpacht A"
---
> "Q9Z104-1","22570500","Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex.","Proceedings of the National Academy of Sciences of the United States of America","2012 May 22","Ceballos-Chavez M, Rivero S, Garcia-Gutierrez P, Rodriguez-Paredes M, Garcia-Dominguez M, Bhattacharya S, Reyes JC"
2187a2401
> "Q6PA06-1","27669642","Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology.","Experimental cell research","2016 Nov 15","Zhao G, Zhu PP, Renvoise B, Maldonado-Baez L, Park SH, Blackstone C"
2202,2204d2415
< "Q8C6K9-1","21477648","Differential and restricted expression of novel collagen VI chains in mouse.","Matrix biology : journal of the International Society for Matrix Biology","2011 May","Gara SK, Grumati P, Squarzoni S, Sabatelli P, Urciuolo A, Bonaldo P, Paulsson M, Wagener R"
< "Q8C6K9-1","18400749","Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI).","The Journal of biological chemistry","2008 Jul 18","Fitzgerald J, Rich C, Zhou FH, Hansen U"
< "Q8C6K9-1","18276594","Three novel collagen VI chains with high homology to the alpha3 chain.","The Journal of biological chemistry","2008 Apr 18","Gara SK, Grumati P, Urciuolo A, Bonaldo P, Kobbe B, Koch M, Paulsson M, Wagener R"
2207a2419,2423
> "Q8BUE4-1","28732772","A brain-specific isoform of apoptosis-inducing factor 2 attenuates ischemia-induced oxidative stress in HT22 cells.","Neurochemistry international","2018 Jan","Xie Y, Wanggou S, Liu Q, Li X, Liu J, Wu M"
> "Q8BUE4-1","26689472","Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling.","Free radical biology &amp; medicine","2016 Feb","Miriyala S, Thippakorn C, Chaiswing L, Xu Y, Noel T, Tovmasyan A, Batinic-Haberle I, Vander Kooi CW, Chi W, Latif AA, Panchatcharam M, Prachayasittikul V, Butterfield DA, Vore M, Moscow J, St Clair DK"
> "Q8BUE4-1","26168492","Apoptosis-inducing Factor, Mitochondrion-associated 2, Regulates Klf1 in a Mouse Erythroleukemia Cell Line.","Anticancer research","2015 Aug","Kojima N, Tanaka Y, Kulkeaw K, Nakanishi Y, Shirasawa S, Sugiyama D"
> "Q8BUE4-1","21366272","Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase.","Biochemistry","2011 Apr 12","Zhou Y, Feng X, Koh DW"
> "Q8BUE4-1","16186796","The p53-inducible apoptotic protein AMID is not required for normal development and tumor suppression.","Oncogene","2006 Feb 9","Mei J, Webb S, Zhang B, Shu HB"
2209c2425,2428
< "P42227-1","30996264","The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration.","Nature communications","2019 Apr 17","Sala D, Cunningham TJ, Stec MJ, Etxaniz U, Nicoletti C, Dall'Agnese A, Puri PL, Duester G, Latella L, Sacco A"
---
> "O70494-1","28359915","Sp3 controls fibroblast growth factor receptor 4 gene activity during myogenic differentiation.","Gene","2017 Jun 20","Cavanaugh E, DiMario JX"
> "O70494-1","28522827","Involvement of GATA1 and Sp3 in the activation of the murine STING gene promoter in NIH3T3 cells.","Scientific reports","2017 May 18","Xu YY, Jin R, Zhou GP, Xu HG"
> "O70494-1","27143785","Transcription factors YY1, Sp1 and Sp3 modulate dystrophin Dp71 gene expression in hepatic cells.","The Biochemical journal","2016 Jul 1","Penuelas-Urquides K, Becerril-Esquivel C, Mendoza-de-Leon LC, Silva-Ramirez B, Davila-Velderrain J, Cisneros B, de Leon MB"
> "O70494-1","11472836","Impaired ossification in mice lacking the transcription factor Sp3.","Mechanisms of development","2001 Aug","Gollner H, Dani C, Phillips B, Philipsen S, Suske G"
2219a2439,2441
> "Q91X88-1","25085363","Role of glycosyltransferase PomGnT1 in glioblastoma progression.","Neuro-oncology","2015 Feb","Lan J, Guo P, Lin Y, Mao Q, Guo L, Ge J, Li X, Jiang J, Lin X, Qiu Y"
> "Q91X88-1","17034757","Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan.","Biochemical and biophysical research communications","2006 Dec 1","Xiong H, Kobayashi K, Tachikawa M, Manya H, Takeda S, Chiyonobu T, Fujikake N, Wang F, Nishimoto A, Morris GE, Nagai Y, Kanagawa M, Endo T, Toda T"
> "Q91X88-1","16458488","A genetic model for muscle-eye-brain disease in mice lacking protein O-mannose 1,2-N-acetylglucosaminyltransferase (POMGnT1).","Mechanisms of development","2006 Mar","Liu J, Ball SL, Yang Y, Mei P, Zhang L, Shi H, Kaminski HJ, Lemmon VP, Hu H"
2222a2445,2451
> "Q8VHL0-1","27914708","Generation and phenotypic analysis of mice lacking all urea transporters.","Kidney international","2017 Feb","Jiang T, Li Y, Layton AT, Wang W, Sun Y, Li M, Zhou H, Yang B"
> "Q8VHL0-1","27091563","Descending thin limb of the intermediate loop expresses both aquaporin 1 and urea transporter A2 in the mouse kidney.","Histochemistry and cell biology","2016 Jul","Kim WY, Lee HW, Han KH, Nam SA, Choi A, Kim YK, Kim J"
> "Q8VHL0-1","26407594","Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3.","Journal of the American Society of Nephrology : JASN","2016 May","Klein JD, Wang Y, Mistry A, LaRocque LM, Molina PA, Rogers RT, Blount MA, Sands JM"
> "Q8VHL0-1","25298344","Extrarenal phenotypes of the UT-B knockout mouse.","Sub-cellular biochemistry","2014","Yang B, Li X, Guo L, Meng Y, Dong Z, Zhao X"
> "Q8VHL0-1","12965892","Lack of UT-B in vasa recta and red blood cells prevents urea-induced improvement of urinary concentrating ability.","American journal of physiology. Renal physiology","2004 Jan","Bankir L, Chen K, Yang B"
> "Q8VHL0-1","12952854","Expression of urea transporters in potassium-depleted mouse kidney.","American journal of physiology. Renal physiology","2003 Dec","Jung JY, Madsen KM, Han KH, Yang CW, Knepper MA, Sands JM, Kim J"
> "Q8VHL0-1","12133842","Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes.","The Journal of biological chemistry","2002 Sep 27","Yang B, Verkman AS"
2224,2225d2452
< "Q8VCQ6-1","30243987","Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1.","Experimental neurology","2019 Jan","Lu MH, Ji WL, Xu DE, Yao PP, Zhao XY, Wang ZT, Fang LP, Huang R, Lan LJ, Chen JB, Wang TH, Cheng LH, Xu RX, Liu CF, Puglielli L, Ma QH"
< "Q8VCQ6-1","27892528","Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus.","Scientific reports","2016 Nov 28","Taniguchi M, Tasaki T, Ninomiya H, Ueda Y, Kuremoto KI, Mitsutake S, Igarashi Y, Okazaki T, Takegami T"
2230a2458,2459
> "Q9ER67-1","15162511","Comparative expression analysis of the MAGED genes during embryogenesis and brain development.","Developmental dynamics : an official publication of the American Association of Anatomists","2004 Jun","Bertrand M, Huijbers I, Chomez P, De Backer O"
> "Q9ER67-1","11856887","Expression pattern and further characterization of human MAGED2 and identification of rodent orthologues.","Cytogenetics and cell genetics","2001","Langnaese K, Kloos DU, Wehnert M, Seidel B, Wieacker P"
2232,2239c2461
< "Q6ZPF3-1","30817801","Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype.","PLoS genetics","2019 Feb","Charron Y, Willert J, Lipkowitz B, Kusecek B, Herrmann BG, Bauer H"
< "O35714-1","30755607","Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.","Nature communications","2019 Feb 12","Galle-Treger L, Sankaranarayanan I, Hurrell BP, Howard E, Lo R, Maazi H, Lewis G, Banie H, Epstein AL, Hu P, Rehan VK, Gilliland FD, Allayee H, Soroosh P, Sharpe AH, Akbari O"
< "O35714-1","29623077","Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.","Frontiers in immunology","2018","Vashist N, Trittel S, Ebensen T, Chambers BJ, Guzman CA, Riese P"
< "O35714-1","28611044","Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells.","Cancer research","2017 Aug 15","Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, Sriram V, Bailey WJ, Herzyk D, McClanahan TK, Willingham A, Beebe AM, Sadekova S"
< "O35714-1","28649380","GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory.","Journal for immunotherapy of cancer","2017","Durham NM, Holoweckyj N, MacGill RS, McGlinchey K, Leow CC, Robbins SH"
< "O35714-1","11869690","CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.","Immunity","2002 Feb","McHugh RS, Whitters MJ, Piccirillo CA, Young DA, Shevach EM, Collins M, Byrne MC"
< "P97868-1","17470788","PACT is a negative regulator of p53 and essential for cell growth and embryonic development.","Proceedings of the National Academy of Sciences of the United States of America","2007 May 8","Li L, Deng B, Xing G, Teng Y, Tian C, Cheng X, Yin X, Yang J, Gao X, Zhu Y, Sun Q, Zhang L, Yang X, He F"
< "P97868-1","15617101","P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA.","Journal of cellular physiology","2005 Jul","Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW"
---
> "Q91VZ6-1","26296315","Mice doubly-deficient in the Arf GAPs SMAP1 and SMAP2 exhibit embryonic lethality.","FEBS letters","2015 Sep 14","Sumiyoshi M, Masuda N, Tanuma N, Ogoh H, Imai E, Otsuka M, Hayakawa N, Ohno K, Matsui Y, Hara K, Gotoh R, Suzuki M, Rai S, Tanaka H, Matsumura I, Shima H, Watanabe T"
2244,2248d2465
< "Q8BTG7-1","28524415","NDRG4, an early detection marker for colorectal cancer, is specifically expressed in enteric neurons.","Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society","2017 Sep","Vaes N, Lentjes MHFM, Gijbels MJ, Rademakers G, Daenen KL, Boesmans W, Wouters KAD, Geuzens A, Qu X, Steinbusch HPJ, Rutten BPF, Baldwin SH, Sharkey KA, Hofstra RMW, van Engeland M, Vanden Berghe P, Melotte V"
< "Q8BTG7-1","27175791","Uterine Expression of NDRG4 Is Induced by Estrogen and Up-Regulated during Embryo Implantation Process in Mice.","PloS one","2016","Yang Q, Gu Y, Zhang X, Wang JM, He YP, Shi Y, Sun ZG, Shi HJ, Wang J"
< "Q8BTG7-1","26780215","N-myc downstream-regulated gene 4, up-regulated by tumor necrosis factor-alpha and nuclear factor kappa B, aggravates cardiac ischemia/reperfusion injury by inhibiting reperfusion injury salvage kinase pathway.","Basic research in cardiology","2016 Mar","Xing Y, Tang B, Zhu C, Li W, Li Z, Zhao J, Gong WD, Wu ZQ, Zhu CC, Zhang YQ"
< "Q8BTG7-1","26801554","Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.","Biochemical and biophysical research communications","2016 Feb 12","Qu X, Li J, Baldwin HS"
< "Q8BTG7-1","17998568","Differential expression patterns of NDRG family proteins in the central nervous system.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2008 Feb","Okuda T, Kokame K, Miyata T"
2250,2251c2467
< "Q8BHS8-1","22975310","The microtubule associated protein syntabulin is required for glucose-stimulated and cAMP-potentiated insulin secretion.","FEBS letters","2012 Oct 19","Ying Y, Li L, Cao W, Yan D, Zeng Q, Kong X, Lu L, Yan M, Xu X, Qu J, Su Q, Ma X"
< "Q8BHS8-1","16750881","Expression of m-Golsyn/Syntabulin gene during mouse brain development.","Neuroscience letters","2006 Aug 7","Funakoshi E, Fukui M, Hamano A, Okamoto H, Sugiyama C, Nishiyama N, Ogita K, Hori T, Shimizu N, Ito F"
---
> "Q80X50-1","25185265","UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.","Blood","2014 Oct 9","Bordeleau ME, Aucagne R, Chagraoui J, Girard S, Mayotte N, Bonneil E, Thibault P, Pabst C, Bergeron A, Barabe F, Hebert J, Sauvageau M, Boutonnet C, Meloche S, Sauvageau G"
2254d2469
< "Q91VM3-1","26000824","The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis.","Autophagy","2015","Zhao YG, Sun L, Miao G, Ji C, Zhao H, Sun H, Miao L, Yoshii SR, Mizushima N, Wang X, Zhang H"
2256a2472,2473
> "Q8BHS8-1","22975310","The microtubule associated protein syntabulin is required for glucose-stimulated and cAMP-potentiated insulin secretion.","FEBS letters","2012 Oct 19","Ying Y, Li L, Cao W, Yan D, Zeng Q, Kong X, Lu L, Yan M, Xu X, Qu J, Su Q, Ma X"
> "Q8BHS8-1","16750881","Expression of m-Golsyn/Syntabulin gene during mouse brain development.","Neuroscience letters","2006 Aug 7","Funakoshi E, Fukui M, Hamano A, Okamoto H, Sugiyama C, Nishiyama N, Ogita K, Hori T, Shimizu N, Ito F"
2263,2264c2480,2481
< "Q9DCG2-1","27316686","Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration.","Journal of immunology (Baltimore, Md. : 1950)","2016 Aug 1","Lo TH, Silveira PA, Fromm PD, Verma ND, Vu PA, Kupresanin F, Adam R, Kato M, Cogger VC, Clark GJ, Hart DN"
< "Q9DCG2-1","17947679","The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration.","Journal of immunology (Baltimore, Md. : 1950)","2007 Nov 1","Kato M, Khan S, d'Aniello E, McDonald KJ, Hart DN"
---
> "Q9CRZ8-1","19729679","Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis.","The Journal of biological chemistry","2009 Oct 30","Fan J, Rone MB, Papadopoulos V"
> "Q8CBW4-1","17660561","Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.","Genetics","2007 Sep","Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH"
2265a2483,2486
> "Q8CE08-1","27783536","Prostatic Acid Phosphatase Alters the RANKL/OPG System and Induces Osteoblastic Prostate Cancer Bone Metastases.","Endocrinology","2016 Dec","Kirschenbaum A, Izadmehr S, Yao S, O'Connor-Chapman KL, Huang A, Gregoriades EM, Yakar S, Levine AC"
> "Q8CE08-1","27348306","Expression of Prostatic Acid Phosphatase in Rat Circumvallate Papillae.","PloS one","2016","Nishida K, Kubota T, Matsumoto S, Kato J, Watanabe Y, Yamamoto A, Furui M, Ohishi A, Nagasawa K"
> "Q8CE08-1","27306411","EXPRESS: NGF-trkA signaling modulates the analgesic effects of prostatic acid phosphatase in resiniferatoxin-induced neuropathy.","Molecular pain","2016","Wu CH, Ho WY, Lee YC, Lin CL, Hsieh YL"
> "Q8CE08-1","19158948","Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception.","PloS one","2009","Sowa NA, Vadakkan KI, Zylka MJ"
2269a2491
> "Q924T3-1","29233683","Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase.","Experimental cell research","2018 Jan 15","Sunatani Y, Kamdar RP, Sharma MK, Matsui T, Sakasai R, Hashimoto M, Ishigaki Y, Matsumoto Y, Iwabuchi K"
2272a2495,2497
> "O08785-1","30530698","Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.","Proceedings of the National Academy of Sciences of the United States of America","2018 Dec 26","Qu M, Duffy T, Hirota T, Kay SA"
> "O08785-1","30124738","Circadian locomotor output cycles kaput accelerates atherosclerotic plaque formation by upregulating plasminogen activator inhibitor-1 expression.","Acta biochimica et biophysica Sinica","2018 Sep 1","Jiang Q, Liu H, Wang S, Wang J, Tang Y, He Z, Wu F, Huang Z, Cong X, Ding R, Liang C"
> "O08785-1","30695595","[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].","Voprosy onkologii","2016","Gubareva EA, Maidin MA, Tyndyk ML, Vinogradova LA, Panchenko AV"
2278d2502
< "Q61473-1","11973269","Depletion of definitive gut endoderm in Sox17-null mutant mice.","Development (Cambridge, England)","2002 May","Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y"
2281c2505,2506
< "Q8BX57-1","16135750","MONaKA, a novel modulator of the plasma membrane Na,K-ATPase.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2005 Aug 31","Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB"
---
> "Q9D6Z0-1","28726787","ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage.","Cell death &amp; disease","2017 Jul 20","Jordan JJ, Chhim S, Margulies CM, Allocca M, Bronson RT, Klungland A, Samson LD, Fu D"
> "Q9D6Z0-1","23572141","Deletion of mouse Alkbh7 leads to obesity.","Journal of molecular cell biology","2013 Jun","Solberg A, Robertson AB, Aronsen JM, Rognmo O, Sjaastad I, Wisloff U, Klungland A"
2299,2303d2523
< "Q8K1E3-1","28863347","Deletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam.","Psychoneuroendocrinology","2017 Nov","Navarrete F, Garcia-Gutierrez MS, Laborda J, Manzanares J"
< "Q8K1E3-1","22306741","DLK2 is a transcriptional target of KLF4 in the early stages of adipogenesis.","Journal of molecular biology","2012 Mar 16","Rivero S, Diaz-Guerra MJ, Monsalve EM, Laborda J, Garcia-Ramirez JJ"
< "Q8K1E3-1","22185379","Characterization of a proximal Sp1 response element in the mouse Dlk2 gene promoter.","BMC molecular biology","2011 Dec 20","Rivero S, Ruiz-Garcia A, Diaz-Guerra MJ, Laborda J, Garcia-Ramirez JJ"
< "Q8K1E3-1","21419176","The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities.","Biochimica et biophysica acta","2011 Jun","Sanchez-Solana B, Nueda ML, Ruvira MD, Ruiz-Hidalgo MJ, Monsalve EM, Rivero S, Garcia-Ramirez JJ, Diaz-Guerra MJ, Baladron V, Laborda J"
< "Q8K1E3-1","17320102","The novel gene EGFL9/Dlk2, highly homologous to Dlk1, functions as a modulator of adipogenesis.","Journal of molecular biology","2007 Apr 13","Nueda ML, Baladron V, Garcia-Ramirez JJ, Sanchez-Solana B, Ruvira MD, Rivero S, Ballesteros MA, Monsalve EM, Diaz-Guerra MJ, Ruiz-Hidalgo MJ, Laborda J"
2325a2546,2547
> "Q5BL07-1","15328346","Structure of the N-terminal domain of PEX1 AAA-ATPase. Characterization of a putative adaptor-binding domain.","The Journal of biological chemistry","2004 Nov 26","Shiozawa K, Maita N, Tomii K, Seto A, Goda N, Akiyama Y, Shimizu T, Shirakawa M, Hiroaki H"
> "Q5BL07-1","15502339","Crystallographic characterization of the N-terminal domain of PEX1.","Acta crystallographica. Section D, Biological crystallography","2004 Nov","Shiozawa K, Maita N, Tomii K, Seto A, Goda N, Akiyama Y, Shimizu T, Shirakawa M, Hiroaki H"
2329,2337d2550
< "Q5SWZ9-1","29113556","Phospholipase D Family Member 6 Is a Surface Marker for Enrichment of Undifferentiated Spermatogonia in Prepubertal Boars.","Stem cells and development","2018 Jan 1","Zhang P, Qin Y, Zheng Y, Zeng W"
< "Q5SWZ9-1","28749988","Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice.","PLoS genetics","2017 Jul","Inoue K, Ichiyanagi K, Fukuda K, Glinka M, Sasaki H"
< "Q5SWZ9-1","28115634","Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.","Nucleic acids research","2017 May 19","Kabayama Y, Toh H, Katanaya A, Sakurai T, Chuma S, Kuramochi-Miyagawa S, Saga Y, Nakano T, Sasaki H"
< "Q5SWZ9-1","27635761","Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division.","Molecular cell","2016 Sep 15","Adachi Y, Itoh K, Yamada T, Cerveny KL, Suzuki TL, Macdonald P, Frohman MA, Ramachandran R, Iijima M, Sesaki H"
< "Q5SWZ9-1","26711011","Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.","Molecular cell","2016 Jan 7","Zhang Y, Liu X, Bai J, Tian X, Zhao X, Liu W, Duan X, Shang W, Fan HY, Tong C"
< "Q5SWZ9-1","23064227","The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.","Nature","2012 Nov 8","Ipsaro JJ, Haase AD, Knott SR, Joshua-Tor L, Hannon GJ"
< "Q5SWZ9-1","22281006","Roles for the lipid-signaling enzyme MitoPLD in mitochondrial dynamics, piRNA biogenesis, and spermatogenesis.","BMB reports","2012 Jan","Gao Q, Frohman MA"
< "Q5SWZ9-1","21397848","piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling.","Developmental cell","2011 Mar 15","Huang H, Gao Q, Peng X, Choi SY, Sarma K, Ren H, Morris AJ, Frohman MA"
< "Q5SWZ9-1","21397847","MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline.","Developmental cell","2011 Mar 15","Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H"
2343a2557,2558
> "P34928-1","17339654","Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification.","Journal of lipid research","2007 Jun","Westerterp M, Berbee JF, Delsing DJ, Jong MC, Gijbels MJ, Dahlmans VE, Offerman EH, Romijn JA, Havekes LM, Rensen PC"
> "Q3URQ7-1","26525917","MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.","Brain : a journal of neurology","2016 Jan","MacNair L, Xiao S, Miletic D, Ghani M, Julien JP, Keith J, Zinman L, Rogaeva E, Robertson J"
2349,2354d2563
< "Q9ET39-1","29305520","Soluble SLAMF6 Receptor Induces Strong CD8(+) T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo.","Cancer immunology research","2018 Feb","Eisenberg G, Engelstein R, Geiger-Maor A, Hajaj E, Merims S, Frankenburg S, Uzana R, Rutenberg A, Machlenkin A, Frei G, Peretz T, Lotem M"
< "Q9ET39-1","28904129","T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.","Journal of immunology (Baltimore, Md. : 1950)","2017 Oct 15","Radomir L, Cohen S, Kramer MP, Bakos E, Lewinsky H, Barak A, Porat Z, Bucala R, Stepensky P, Becker-Herman S, Shachar I"
< "Q9ET39-1","28373584","Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions.","Journal of immunology (Baltimore, Md. : 1950)","2017 May 15","Baglaenko Y, Cruz Tleugabulova M, Gracey E, Talaei N, Manion KP, Chang NH, Ferri DM, Mallevaey T, Wither JE"
< "Q9ET39-1","27223891","CRISPR-Mediated Slamf1Delta/Delta Slamf5Delta/Delta Slamf6Delta/Delta Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects.","PloS one","2016","Hu JK, Crampton JC, Locci M, Crotty S"
< "Q9ET39-1","26878112","A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.","Nature immunology","2016 Apr","Wu N, Zhong MC, Roncagalli R, Perez-Quintero LA, Guo H, Zhang Z, Lenoir C, Dong Z, Latour S, Veillette A"
< "Q9ET39-1","15879084","Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions.","Journal of immunology (Baltimore, Md. : 1950)","2005 May 15","Howie D, Laroux FS, Morra M, Satoskar AR, Rosas LE, Faubion WA, Julien A, Rietdijk S, Coyle AJ, Fraser C, Terhorst C"
2362a2572,2578
> "Q3UHC7-1","27476001","DAB2IP regulates EMT and metastasis of prostate cancer through targeting PROX1 transcription and destabilizing HIF1alpha protein.","Cellular signalling","2016 Nov","Wang B, Huang J, Zhou J, Hui K, Xu S, Fan J, Li L, Wang X, Hsieh JT, He D, Wu K"
> "Q3UHC7-1","26512963","DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis.","Cell death &amp; disease","2015 Oct 29","Zhou J, Ning Z, Wang B, Yun EJ, Zhang T, Pong RC, Fazli L, Gleave M, Zeng J, Fan J, Wang X, Li L, Hsieh JT, He D, Wu K"
> "Q3UHC7-1","26139244","AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis.","Cancer research","2015 Sep 1","Ji W, Li Y, He Y, Yin M, Zhou HJ, Boggon TJ, Zhang H, Min W"
> "Q3UHC7-1","26181199","AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment.","Cell death &amp; disease","2015 Jul 16","Xu J, Wan P, Wang M, Zhang J, Gao X, Hu B, Han J, Chen L, Sun K, Wu J, Wu X, Huang X, Chen J"
> "Q3UHC7-1","25995115","Single-molecule imaging of a three-component ordered actin disassembly mechanism.","Nature communications","2015 May 21","Jansen S, Collins A, Chin SM, Ydenberg CA, Gelles J, Goode BL"
> "Q3UHC7-1","18281285","AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response.","The Journal of biological chemistry","2008 May 2","Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W"
> "Q3UHC7-1","12877983","Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain.","Brain research. Molecular brain research","2003 Jul 23","Homayouni R, Magdaleno S, Keshvara L, Rice DS, Curran T"
2371,2377d2586
< "Q9Z2G6-1","28920918","Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus.","The Journal of clinical investigation","2017 Oct 2","Bichet DG, Lussier Y"
< "Q9Z2G6-1","20170518","SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.","BMC developmental biology","2010 Feb 19","Li S, Francisco AB, Munroe RJ, Schimenti JC, Long Q"
< "Q811P8-1","30045817","The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice.","EBioMedicine","2018 Aug","Nakamura T, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akiyama T"
< "Q811P8-1","17663722","PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2007 Aug","Hayashi T, Okabe T, Nasu-Nishimura Y, Sakaue F, Ohwada S, Matsuura K, Akiyama T, Nakamura T"
< "Q811P8-1","17272280","p200 RhoGAP promotes cell proliferation by mediating cross-talk between Ras and Rho signaling pathways.","The Journal of biological chemistry","2007 Mar 23","Shang X, Moon SY, Zheng Y"
< "Q811P8-1","16716191","Role of the Rho GTPase-activating protein RICS in neurite outgrowth.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2006 Jun","Nasu-Nishimura Y, Hayashi T, Ohishi T, Okabe T, Ohwada S, Hasegawa Y, Senda T, Toyoshima C, Nakamura T, Akiyama T"
< "Q811P8-1","12531901","RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.","The Journal of biological chemistry","2003 Mar 14","Okabe T, Nakamura T, Nishimura YN, Kohu K, Ohwada S, Morishita Y, Akiyama T"
2379c2588,2589
< "Q9JLL3-1","29237753","Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney.","Proceedings of the National Academy of Sciences of the United States of America","2017 Dec 26","Schutgens F, Rookmaaker MB, Blokzijl F, van Boxtel R, Vries R, Cuppen E, Verhaar MC, Clevers H"
---
> "Q8BGC0-1","24352707","Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior.","Brain structure &amp; function","2015 Mar","Hahn YK, Podhaizer EM, Farris SP, Miles MF, Hauser KF, Knapp PE"
> "Q8BGC0-1","15485897","FF domains of CA150 bind transcription and splicing factors through multiple weak interactions.","Molecular and cellular biology","2004 Nov","Smith MJ, Kulkarni S, Pawson T"
2380a2591,2593
> "Q6PAM1-1","26494466","Unexpected requirement for a binding partner of the syntaxin family in phagocytosis by murine testicular Sertoli cells.","Cell death and differentiation","2016 May","Dong YS, Hou WG, Li Y, Liu DB, Hao GZ, Zhang HF, Li JC, Zhao J, Zhang S, Liang GB, Li W"
> "Q6PAM1-1","19663695","Characteristics of a novel monoclonal antibody against interleukin-14alpha.","Hybridoma (2005)","2009 Aug","Peng X, Zhou C, Wei D, Luo Z, Zhang C"
> "Q6PAM1-1","19038581","IL-14 alpha, the nexus for primary Sjogren's disease in mice and humans.","Clinical immunology (Orlando, Fla.)","2009 Mar","Shen L, Suresh L, Li H, Zhang C, Kumar V, Pankewycz O, Ambrus JL Jr"
2398a2612,2614
> "Q99MK9-1","29382819","RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.","Nature communications","2018 Jan 30","Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E"
> "Q99MK9-1","27765918","beta-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patients.","Oncotarget","2016 Oct 18","Schirosi L, Mazzotta A, Opinto G, Pinto R, Graziano G, Tommasi S, Fucci L, Simone G, Mangia A"
> "Q99MK9-1","15665283","Tumor susceptibility of Rassf1a knockout mice.","Cancer research","2005 Jan 1","Tommasi S, Dammann R, Zhang Z, Wang Y, Liu L, Tsark WM, Wilczynski SP, Li J, You M, Pfeifer GP"
2404c2620,2621
< "Q5DW34-1","16702210","Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP.","The Journal of biological chemistry","2006 Jul 21","Ueda J, Tachibana M, Ikura T, Shinkai Y"
---
> "Q9JHG7-1","29038423","Regulation of T cell alloimmunity by PI3Kgamma and PI3Kdelta.","Nature communications","2017 Oct 16","Uehara M, McGrath MM, Ohori S, Solhjou Z, Banouni N, Routray S, Evans C, DiNitto JP, Elkhal A, Turka LA, Strom TB, Tullius SG, Winkler DG, Azzi J, Abdi R"
> "P98084-1","27268412","Expression and localization of X11 family proteins in neurons.","Brain research","2016 Sep 1","Motodate R, Saito Y, Hata S, Suzuki T"
2418a2636,2637
> "Q9ET26-1","23645206","ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.).","Cell death and differentiation","2013 Aug","Han J, Kim YL, Lee KW, Her NG, Ha TK, Yoon S, Jeong SI, Lee JH, Kang MJ, Lee MG, Ryu BK, Baik JH, Chi SG"
> "Q8BRB7-1","22951486","Histone H3 lysine 4 monomethylation (H3K4me1) and H3 lysine 9 monomethylation (H3K9me1): distribution and their association in regulating gene expression under hyperglycaemic/hyperinsulinemic conditions in 3T3 cells.","Biochimie","2012 Dec","Gupta J, Kumar S, Li J, Krishna Murthy Karuturi R, Tikoo K"
2421,2422c2640,2647
< "Q3U1J1-1","17041757","Apoptosis promoted by up-regulation of TFPT (TCF3 fusion partner) appears p53 independent, cell type restricted and cell density influenced.","Apoptosis : an international journal on programmed cell death","2006 Dec","Franchini C, Fontana F, Minuzzo M, Babbio F, Privitera E"
< "Q8BP71-1","30867288","RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.","Proceedings of the National Academy of Sciences of the United States of America","2019 Mar 26","Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, Gou LT, Zhou Y, Zhang J, Ren S, Chen J, Wang Y, Fu XD"
---
> "Q3UNX5-1","25744306","High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the adipose tissue, along with increased expression of extracellular matrix remodelling- and inflammation-related genes.","The British journal of nutrition","2015 Mar 28","Choi MS, Kim YJ, Kwon EY, Ryoo JY, Kim SR, Jung UJ"
> "Q3UNX5-1","12707288","Analysis of the role of the SA gene in blood pressure regulation by gene targeting.","Hypertension (Dallas, Tex. : 1979)","2003 Jun","Walsh V, Somody L, Farrell A, Zhang B, Brown J, Pritchard C, Vincent M, Samani NJ"
> "O08644-1","28262839","Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.","Scientific reports","2017 Mar 6","Mateo-Lozano S, Bazzocco S, Rodrigues P, Mazzolini R, Andretta E, Dopeso H, Fernandez Y, Del Llano E, Bilic J, Suarez-Lopez L, Macaya I, Carton-Garcia F, Nieto R, Jimenez-Flores LM, de Marcondes PG, Nunez Y, Afonso E, Cacci K, Hernandez-Losa J, Landolfi S, Abasolo I, Ramon Y Cajal S, Mariadason JM, Schwartz S Jr, Matsui T, Arango D"
> "Q06138-1","21903876","Characterization of the liver kinase B1-mouse protein-25 -Ste-20-related adaptor protein complex in adult mouse skeletal muscle.","Journal of applied physiology (Bethesda, Md. : 1985)","2011 Dec","Smith CD, Compton RA, Bowler JS, Kemp JT, Sudweeks SN, Thomson DM, Winder WW"
> "Q91ZS8-1","28640668","Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mouse.","RNA biology","2017 Nov 2","Filippini A, Bonini D, Lacoux C, Pacini L, Zingariello M, Sancillo L, Bosisio D, Salvi V, Mingardi J, La Via L, Zalfa F, Bagni C, Barbon A"
> "Q91ZS8-1","28395340","Testicular adenosine to inosine RNA editing in the mouse is mediated by ADARB1.","Biology of reproduction","2017 Jan 1","Snyder EM, Licht K, Braun RE"
> "Q91ZS8-1","16382140","Altered RNA editing in mice lacking ADAR2 autoregulation.","Molecular and cellular biology","2006 Jan","Feng Y, Sansam CL, Singh M, Emeson RB"
> "Q924X7-1","16176263","Differential expression pattern of the novel serine/threonine kinase, STK33, in mice and men.","The FEBS journal","2005 Oct","Mujica AO, Brauksiepe B, Saaler-Reinhardt S, Reuss S, Schmidt ER"
2427a2653,2654
> "Q8BN78-1","28882591","The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.","Biochemical and biophysical research communications","2017 Nov 4","Robinson SC, Donaldson-Kabwe NS, Dvorkin-Gheva A, Longo J, He L, Daniel JM"
> "Q8BN78-1","15282317","Regulation of the rapsyn promoter by kaiso and delta-catenin.","Molecular and cellular biology","2004 Aug","Rodova M, Kelly KF, VanSaun M, Daniel JM, Werle MJ"
2429a2657,2661
> "Q8CI15-1","29673590","The cross roles of sphingosine kinase 1/2 and ceramide glucosyltransferase in cell growth and death.","Biochemical and biophysical research communications","2018 Jun 7","Qin J, Kilkus JP, Dawson G"
> "Q8CI15-1","17643421","Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway.","Experimental cell research","2007 Sep 10","Soldi R, Mandinova A, Venkataraman K, Hla T, Vadas M, Pitson S, Duarte M, Graziani I, Kolev V, Kacer D, Kirov A, Maciag T, Prudovsky I"
> "Q8CI15-1","16623665","Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.","The Biochemical journal","2006 Aug 1","Venkataraman K, Thangada S, Michaud J, Oo ML, Ai Y, Lee YM, Wu M, Parikh NS, Khan F, Proia RL, Hla T"
> "Q8CI15-1","16368679","Mouse sphingosine kinase isoforms SPHK1a and SPHK1b differ in enzymatic traits including stability, localization, modification, and oligomerization.","The Journal of biological chemistry","2006 Feb 17","Kihara A, Anada Y, Igarashi Y"
> "Q8CI15-1","12391145","Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases.","Molecular and cellular biology","2002 Nov","Shu X, Wu W, Mosteller RD, Broek D"
2436a2669,2671
> "Q3UMB5-1","29950492","The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis.","Genes &amp; development","2018 Jul 1","Zhang Y, Burberry A, Wang JY, Sandoe J, Ghosh S, Udeshi ND, Svinkina T, Mordes DA, Mok J, Charlton M, Li QZ, Carr SA, Eggan K"
> "Q3UMB5-1","27875531","Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.","PLoS genetics","2016 Nov","Ugolino J, Ji YJ, Conchina K, Chu J, Nirujogi RS, Pandey A, Brady NR, Hamacher-Brady A, Wang J"
> "Q3UMB5-1","27617292","A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.","Science advances","2016 Sep","Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, Chen JF"
2437a2673,2679
> "Q8CIV7-1","27310661","Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression.","PloS one","2016","Shen AL, Moran SA, Glover EA, Drinkwater NR, Swearingen RE, Teixeira LB, Bradfield CA"
> "Q8CIV7-1","26619963","OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.","Gastroenterology","2016 Mar","Ye GD, Sun GB, Jiao P, Chen C, Liu QF, Huang XL, Zhang R, Cai WY, Li SN, Wu JF, Liu YJ, Wu RS, Xie YY, Chan EC, Liou YC, Li BA"
> "Q8CIV7-1","12213202","Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice.","Genomics","2002 Sep","Li B, Dai Q, Li L, Nair M, Mackay DR, Dai X"
> "Q91V57-1","28346224","Mutant alpha2-chimaerin signals via bidirectional ephrin pathways in Duane retraction syndrome.","The Journal of clinical investigation","2017 May 1","Nugent AA, Park JG, Wei Y, Tenney AP, Gilette NM, DeLisle MM, Chan WM, Cheng L, Engle EC"
> "Q91V57-1","17719550","Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling.","Cell","2007 Aug 24","Iwasato T, Katoh H, Nishimaru H, Ishikawa Y, Inoue H, Saito YM, Ando R, Iwama M, Takahashi R, Negishi M, Itohara S"
> "Q91V57-1","16446429","The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology.","Proceedings of the National Academy of Sciences of the United States of America","2006 Feb 7","Buttery P, Beg AA, Chih B, Broder A, Mason CA, Scheiffele P"
> "Q91V57-1","15447672","Chimaerins act downstream from neurotrophins in overcoming the inhibition of neurite outgrowth produced by myelin-associated glycoprotein.","Journal of neurochemistry","2004 Oct","Mizuno T, Yamashita T, Tohyama M"
2439,2442d2680
< "A2CG63-1","28207192","Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network.","Stem cells (Dayton, Ohio)","2017 Jun","Wu RC, Zeng Y, Chen YF, Lanz RB, Wu MY"
< "A2CG63-1","26258622","Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.","Molecular endocrinology (Baltimore, Md.)","2015 Sep","Wu RC, Zeng Y, Pan IW, Wu MY"
< "A2CG63-1","23487765","ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.","Proceedings of the National Academy of Sciences of the United States of America","2013 Mar 19","Wu RC, Jiang M, Beaudet AL, Wu MY"
< "A2CG63-1","18728284","Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.","Journal of the National Cancer Institute","2008 Sep 3","Wu MY, Eldin KW, Beaudet AL"
2448,2452c2686,2693
< "Q8BQY8-1","25915840","HUS1 regulates in vivo responses to genotoxic chemotherapies.","Oncogene","2016 Feb 4","Balmus G, Lim PX, Oswald A, Hume KR, Cassano A, Pierre J, Hill A, Huang W, August A, Stokol T, Southard T, Weiss RS"
< "Q8BQY8-1","23468651","Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.","PLoS genetics","2013","Lyndaker AM, Lim PX, Mleczko JM, Diggins CE, Holloway JK, Holmes RJ, Kan R, Schlafer DH, Freire R, Cohen PE, Weiss RS"
< "Q8BQY8-1","22575700","Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.","Human molecular genetics","2012 Aug 1","Balmus G, Zhu M, Mukherjee S, Lyndaker AM, Hume KR, Lee J, Riccio ML, Reeves AP, Sutter NB, Noden DM, Peters RM, Weiss RS"
< "Q8BQY8-1","19918068","Dual inactivation of Hus1 and p53 in the mouse mammary gland results in accumulation of damaged cells and impaired tissue regeneration.","Proceedings of the National Academy of Sciences of the United States of America","2009 Dec 15","Yazinski SA, Westcott PM, Ong K, Pinkas J, Peters RM, Weiss RS"
< "Q8BQY8-1","17220276","Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1.","Molecular and cellular biology","2007 Mar","Levitt PS, Zhu M, Cassano A, Yazinski SA, Liu H, Darfler J, Peters RM, Weiss RS"
---
> "Q8R1G6-1","29852170","Suppression of NF-kappaB activation by PDLIM2 restrains hepatic lipogenesis and inflammation in high fat diet induced mice.","Biochemical and biophysical research communications","2018 Sep 5","Hao YR, Tang FJ, Zhang X, Wang H"
> "Q8R1G6-1","28315683","Klotho ameliorates cyclosporine A-induced nephropathy via PDLIM2/NF-kB p65 signaling pathway.","Biochemical and biophysical research communications","2017 Apr 29","Jin M, Lv P, Chen G, Wang P, Zuo Z, Ren L, Bi J, Yang CW, Mei X, Han D"
> "Q8R1G6-1","22155789","PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3.","Science signaling","2011 Dec 6","Tanaka T, Yamamoto Y, Muromoto R, Ikeda O, Sekine Y, Grusby MJ, Kaisho T, Matsuda T"
> "Q8R1G6-1","17468759","PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit.","Nature immunology","2007 Jun","Tanaka T, Grusby MJ, Kaisho T"
> "Q8R1G6-1","15963787","SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling.","Immunity","2005 Jun","Tanaka T, Soriano MA, Grusby MJ"
> "Q8R1G6-1","15659642","Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth.","Molecular biology of the cell","2005 Apr","Loughran G, Healy NC, Kiely PA, Huigsloot M, Kedersha NL, O'Connor R"
> "P81069-1","22862946","Targeting tetramer-forming GABPbeta isoforms impairs self-renewal of hematopoietic and leukemic stem cells.","Cell stem cell","2012 Aug 3","Yu S, Jing X, Colgan JD, Zhao DM, Xue HH"
> "P81069-1","18628204","GABPbeta2 is dispensible for normal lymphocyte development but moderately affects B cell responses.","The Journal of biological chemistry","2008 Sep 5","Jing X, Zhao DM, Waldschmidt TJ, Xue HH"
2454,2458c2695
< "Q0VGM9-1","29290468","Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe.","Cell","2018 Jan 25","Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton SJ"
< "Q0VGM9-1","24115439","RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.","Science (New York, N.Y.)","2013 Oct 11","Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H, Boulton SJ"
< "Q0VGM9-1","22593209","RTEL1 contributes to DNA replication and repair and telomere maintenance.","Molecular biology of the cell","2012 Jul","Uringa EJ, Lisaingo K, Pickett HA, Brind'Amour J, Rohde JH, Zelensky A, Essers J, Lansdorp PM"
< "P70196-1","30190125","Autoimmune sialadenitis is associated with the upregulation of chemokine/chemokine receptor pairs in T cell-specific TRAF6-deficient mice.","Biochemical and biophysical research communications","2018 Sep 26","Noguchi K, Kamiyama N, Hidano S, Gendo Y, Sonoda A, Ozaki T, Hirose H, Sachi N, Saechue B, Ozaka S, Eshita Y, Mizukami K, Kawano K, Kobayashi T"
< "P70196-1","30103950","Inhibition of TRAF6 alleviates choroidal neovascularization in vivo.","Biochemical and biophysical research communications","2018 Sep 18","Ding D, Zhu M, Liu X, Jiang L, Xu J, Chen L, Liang J, Li L, Zhou T, Wang Y, Shi H, Yuan Y, Song E"
---
> "D3YZU1-1","28963042","Behavioral phenotypes and neurobiological mechanisms in the Shank1 mouse model for autism spectrum disorder: A translational perspective.","Behavioural brain research","2018 Oct 15","Sungur AO, Schwarting RKW, Wohr M"
2473c2710,2719
< "Q6P8Y7-1","24914955","SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cells.","PloS one","2014","Vieira N, Deng FM, Liang FX, Liao Y, Chang J, Zhou G, Zheng W, Simon JP, Ding M, Wu XR, Romih R, Kreibich G, Sun TT"
---
> "Q7TSD4-1","24361585","Spatial gene's (Tbata) implication in neurite outgrowth and dendrite patterning in hippocampal neurons.","Molecular and cellular neurosciences","2014 Mar","Yammine M, Saade M, Chauvet S, Nguyen C"
> "Q7TSD4-1","20937703","Tbata modulates thymic stromal cell proliferation and thymus function.","The Journal of experimental medicine","2010 Oct 25","Flomerfelt FA, El Kassar N, Gurunathan C, Chua KS, League SC, Schmitz S, Gershon TR, Kapoor V, Yan XY, Schwartz RH, Gress RE"
> "Q7TSD4-1","19918778","Spatial (Tbata) expression in mature medullary thymic epithelial cells.","European journal of immunology","2010 Feb","Saade M, Irla M, Yammine M, Boulanger N, Victorero G, Vincentelli R, Penninger JM, Hollander GA, Chauvet S, Nguyen C"
> "Q7TSD4-1","17961552","Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17.","Experimental cell research","2007 Dec 10","Irla M, Saade M, Fernandez C, Chasson L, Victorero G, Dahmane N, Chazal G, Nguyen C"
> "Q7TSD4-1","17196196","Dynamic distribution of Spatial during mouse spermatogenesis and its interaction with the kinesin KIF17b.","Experimental cell research","2007 Feb 1","Saade M, Irla M, Govin J, Victorero G, Samson M, Nguyen C"
> "Q7TSD4-1","15236666","Genomic organization and the tissue distribution of alternatively spliced isoforms of the mouse Spatial gene.","BMC genomics","2004 Jul 5","Irla M, Puthier D, Granjeaud S, Saade M, Victorero G, Mattei MG, Nguyen C"
> "Q7TSD4-1","11196687","Spatial, a gene expressed in thymic stromal cells, depends on three-dimensional thymus organization for its expression.","Genes and immunity","2000 Aug","Flomerfelt FA, Kim MG, Schwartz RH"
> "Q3U9N9-1","24248460","Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency.","Endocrinology","2014 Jan","Muller J, Mayerl S, Visser TJ, Darras VM, Boelen A, Frappart L, Mariotta L, Verrey F, Heuer H"
> "Q3U9N9-1","17273864","Recycling of aromatic amino acids via TAT1 allows efflux of neutral amino acids via LAT2-4F2hc exchanger.","Pflugers Archiv : European journal of physiology","2007 Jun","Ramadan T, Camargo SM, Herzog B, Bordin M, Pos KM, Verrey F"
> "Q3U9N9-1","16245314","Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway.","Journal of cellular physiology","2006 Mar","Ramadan T, Camargo SM, Summa V, Hunziker P, Chesnov S, Pos KM, Verrey F"
2478d2723
< "P37242-1","29753845","Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling.","Toxicology letters","2018 Sep 15","Yu Z, Han Y, Shen R, Huang K, Xu YY, Wang QN, Zhou SS, Xu DX, Tao FB"
2480,2484d2724
< "Q9CWZ3-1","28916722","Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing.","The Journal of biological chemistry","2017 Nov 3","Shinde MY, Sidoli S, Kulej K, Mallory MJ, Radens CM, Reicherter AL, Myers RL, Barash Y, Lynch KW, Garcia BA, Klein PS"
< "Q9CWZ3-1","28404883","miR-29a regulates the proliferation and differentiation of retinal progenitors by targeting Rbm8a.","Oncotarget","2017 May 9","Zhang Y, Shen B, Zhang D, Wang Y, Tang Z, Ni N, Jin X, Luo M, Sun H, Gu P"
< "Q9CWZ3-1","27618312","Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.","PLoS genetics","2016 Sep","Mao H, McMahon JJ, Tsai YH, Wang Z, Silver DL"
< "Q9CWZ3-1","26094033","A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.","Neural development","2015 Jun 21","Zou D, McSweeney C, Sebastian A, Reynolds DJ, Dong F, Zhou Y, Deng D, Wang Y, Liu L, Zhu J, Zou J, Shi Y, Albert I, Mao Y"
< "Q9CWZ3-1","23638902","An EJC factor RBM8a regulates anxiety behaviors.","Current molecular medicine","2013 Jul","Alachkar A, Jiang D, Harrison M, Zhou Y, Chen G, Mao Y"
2485a2726,2727
> "Q80ZM8-1","22584571","Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency.","The Journal of biological chemistry","2012 Jul 20","Kiebish MA, Yang K, Sims HF, Jenkins CM, Liu X, Mancuso DJ, Zhao Z, Guan S, Abendschein DR, Han X, Gross RW"
> "Q80ZM8-1","20652826","Cardiolipin synthase-1 mRNA expression does not correlate with endogenous cardiolipin synthase enzyme activity in vitro and in vivo in mammalian lipopolysaccharide models of inflammation.","Inflammation","2011 Aug","Lu B, Xu FY, Taylor WA, Feingold KR, Hatch GM"
2489,2491d2730
< "Q923X4-1","29274570","Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria.","Redox biology","2018 May","Chalker J, Gardiner D, Kuksal N, Mailloux RJ"
< "Q923X4-1","29101900","Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies.","Redox biology","2018 Apr","Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME"
< "Q923X4-1","28618115","Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia.","Glia","2017 Sep","Lepka K, Volbracht K, Bill E, Schneider R, Rios N, Hildebrandt T, Ingwersen J, Prozorovski T, Lillig CH, van Horssen J, Steinman L, Hartung HP, Radi R, Holmgren A, Aktas O, Berndt C"
2493c2732,2734
< "Q62418-1","22450813","The mammalian actin-binding protein 1 is critical for spreading and intraluminal crawling of neutrophils under flow conditions.","Journal of immunology (Baltimore, Md. : 1950)","2012 May 1","Hepper I, Schymeinsky J, Weckbach LT, Jakob SM, Frommhold D, Sixt M, Laschinger M, Sperandio M, Walzog B"
---
> "Q06219-1","30267803","Nurr1 exacerbates cerebral ischemia-reperfusion injury via modulating YAP-INF2-mitochondrial fission pathways.","The international journal of biochemistry &amp; cell biology","2018 Nov","Zhang Z, Yu J"
> "Q06219-1","30111648","Compensatory Expression of Nur77 and Nurr1 Regulates NF-kappaB-Dependent Inflammatory Signaling in Astrocytes.","Molecular pharmacology","2018 Oct","Popichak KA, Hammond SL, Moreno JA, Afzali MF, Backos DS, Slayden RD, Safe S, Tjalkens RB"
> "Q9ERV7-1","28432080","NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.","The Journal of cell biology","2017 Jun 5","Ando K, Parsons MJ, Shah RB, Charendoff CI, Paris SL, Liu PH, Fassio SR, Rohrman BA, Thompson R, Oberst A, Sidi S, Bouchier-Hayes L"
2495,2501d2735
< "Q91ZD6-1","29029019","Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice.","Endocrinology","2017 Dec 1","Wang Y, Pascal LE, Zhong M, Ai J, Wang D, Jing Y, Pilch J, Song Q, Rigatti LH, Graham LE, Nelson JB, Parwani AV, Wang Z"
< "Q91ZD6-1","26935903","EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity.","Nature communications","2016 Mar 3","Li Y, Takahashi Y, Fujii S, Zhou Y, Hong R, Suzuki A, Tsubata T, Hase K, Wang JY"
< "Q91ZD6-1","26328919","Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice.","Molecular medicine reports","2015 Nov","Jiang Y, Fu R, Zhao J, Wu D, Qiao G, Li R, Zhang J"
< "Q91ZD6-1","24260246","Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice.","PloS one","2013","Pascal LE, Ai J, Masoodi KZ, Wang Y, Wang D, Eisermann K, Rigatti LH, O'Malley KJ, Ma HM, Wang X, Dar JA, Parwani AV, Simons BW, Ittman MM, Li L, Davies BJ, Wang Z"
< "Q91ZD6-1","17873910","U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia.","Oncogene","2008 Mar 6","Xiao W, Zhang Q, Habermacher G, Yang X, Zhang AY, Cai X, Hahn J, Liu J, Pins M, Doglio L, Dhir R, Gingrich J, Wang Z"
< "Q91ZD6-1","17892859","Defective FESTA/EAF2-mediated transcriptional activation in S-II-deficient embryonic stem cells.","Biochemical and biophysical research communications","2007 Nov 23","Ito T, Saso K, Arimitsu N, Sekimizu K"
< "Q91ZD6-1","14517999","Expression of murine ELL-associated factor 2 (Eaf2) is developmentally regulated.","Developmental dynamics : an official publication of the American Association of Anatomists","2003 Oct","Li M, Wu X, Zhuang F, Jiang S, Jiang M, Liu YH"
2503c2737,2738
< "Q920B0-1","29947801","An FRMD4B variant suppresses dysplastic photoreceptor lesions in models of enhanced S-cone syndrome and of Nrl deficiency.","Human molecular genetics","2018 Oct 1","Kong Y, Zhao L, Charette JR, Hicks WL, Stone L, Nishina PM, Naggert JK"
---
> "P17095-2","29316384","HMGA1 Overexpression is Associated With the Malignant Status and Progression of Breast Cancer.","Anatomical record (Hoboken, N.J. : 2007)","2018 Jun","Qi C, Cao J, Li M, Liang C, He Y, Li Y, Li J, Zheng X, Wang L, Wei B"
> "P17095-2","29101051","Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1.","Biochimica et biophysica acta. Molecular basis of disease","2018 Feb","Xue W, Huang J, Chen H, Zhang Y, Zhu X, Li J, Zhang W, Yuan Y, Wang Y, Zheng L, Huang K"
2510a2746
> "Q9JKV9-1","17878297","IL-20 is an arteriogenic cytokine that remodels collateral networks and improves functions of ischemic hind limbs.","Proceedings of the National Academy of Sciences of the United States of America","2007 Sep 25","Tritsaris K, Myren M, Ditlev SB, Hubschmann MV, van der Blom I, Hansen AJ, Olsen UB, Cao R, Zhang J, Jia T, Wahlberg E, Dissing S, Cao Y"
2512,2514c2748,2751
< "Q5DTL9-1","24905082","Neuron type- and input pathway-dependent expression of Slc4a10 in adult mouse brains.","The European journal of neuroscience","2014 Sep","Song X, Yamasaki M, Miyazaki T, Konno K, Uchigashima M, Watanabe M"
< "Q5DTL9-1","15567717","Expression of the sodium-driven chloride bicarbonate exchanger NCBE during prenatal mouse development.","Gene expression patterns : GEP","2004 Dec","Hubner CA, Hentschke M, Jacobs S, Hermans-Borgmeyer I"
< "Q5DTL9-1","14592810","A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.","American journal of physiology. Cell physiology","2004 Mar","Praetorius J, Nejsum LN, Nielsen S"
---
> "Q6ZPI3-1","28530657","Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis.","Nature cell biology","2017 Jun","Celia-Terrassa T, Liu DD, Choudhury A, Hang X, Wei Y, Zamalloa J, Alfaro-Aco R, Chakrabarti R, Jiang YZ, Koh BI, Smith HA, DeCoste C, Li JJ, Shao ZM, Kang Y"
> "Q6ZPI3-1","25366156","Splicing variants of NOL4 differentially regulate the transcription activity of Mlr1 and Mlr2 in cultured cells.","Zoological science","2014 Nov","Takayanagi-Kiya S, Misawa-Hojo K, Kiya T, Kunieda T, Kubo T"
> "Q6ZPI3-1","12560079","Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1).","FEBS letters","2003 Jan 30","Kunieda T, Park JM, Takeuchi H, Kubo T"
> "Q99LI2-1","30157172","Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa.","PLoS genetics","2018 Aug","Li L, Jiao X, D'Atri I, Ono F, Nelson R, Chan CC, Nakaya N, Ma Z, Ma Y, Cai X, Zhang L, Lin S, Hameed A, Chioza BA, Hardy H, Arno G, Hull S, Khan MI, Fasham J, Harlalka GV, Michaelides M, Moore AT, Coban Akdemir ZH, Jhangiani S, Lupski JR, Cremers FPM, Qamar R, Salman A, Chilton J, Self J, Ayyagari R, Kabir F, Naeem MA, Ali M, Akram J, Sieving PA, Riazuddin S, Baple EL, Riazuddin SA, Crosby AH, Hejtmancik JF"
2516a2754,2756
> "Q9JII5-1","23965306","DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.","Nucleic acids research","2013 Nov","Chen HY, Yu YH, Yen PH"
> "Q9JII5-1","23658607","Differential translation of Dazap1 transcripts during spermatogenesis.","PloS one","2013","Yang CK, Yen P"
> "Q9JII5-1","18669443","DAZAP1, an hnRNP protein, is required for normal growth and spermatogenesis in mice.","RNA (New York, N.Y.)","2008 Sep","Hsu LC, Chen HY, Lin YW, Chu WC, Lin MJ, Yan YT, Yen PH"
2524,2525d2763
< "Q8BXA0-1","27225731","SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development.","Scientific reports","2016 May 26","Choi Y, Nam J, Whitcomb DJ, Song YS, Kim D, Jeon S, Um JW, Lee SG, Woo J, Kwon SK, Li Y, Mah W, Kim HM, Ko J, Cho K, Kim E"
< "Q8BXA0-1","27152329","Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM.","Science advances","2016 Apr","Zhu Y, Yao S, Augustine MM, Xu H, Wang J, Sun J, Broadwater M, Ruff W, Luo L, Zhu G, Tamada K, Chen L"
2528a2767,2768
> "Q99J99-1","26519030","MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery.","American journal of physiology. Heart and circulatory physiology","2016 Jan 1","Kuo MM, Kim DH, Jandu S, Bergman Y, Tan S, Wang H, Pandey DR, Abraham TP, Shoukas AA, Berkowitz DE, Santhanam L"
> "Q99J99-1","26437775","Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain.","Scientific reports","2015 Oct 6","Kimura Y, Toyofuku Y, Koike S, Shibuya N, Nagahara N, Lefer D, Ogasawara Y, Kimura H"
2529a2770,2771
> "Q5RKZ7-1","15862276","The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis.","Molecular genetics and metabolism","2005 May","Reiss J, Bonin M, Schwegler H, Sass JO, Garattini E, Wagner S, Lee HJ, Engel W, Riess O, Schwarz G"
> "Q8BGV8-1","23921378","Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.","The Journal of biological chemistry","2013 Sep 20","Palmer CS, Elgass KD, Parton RG, Osellame LD, Stojanovski D, Ryan MT"
2531,2536c2773
< "Q80VW7-1","21606955","Coordinate activation of inflammatory gene networks, alveolar destruction and neonatal death in AKNA deficient mice.","Cell research","2011 Nov","Ma W, Ortiz-Quintero B, Rangel R, McKeller MR, Herrera-Rodriguez S, Castillo EF, Schluns KS, Hall M, Zhang H, Suh WK, Okada H, Mak TW, Zhou Y, Blackburn MR, Martinez-Valdez H"
< "Q3TEA8-1","27460150","Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.","Neurobiology of aging","2016 Oct","Neuner SM, Garfinkel BP, Wilmott LA, Ignatowska-Jankowska BM, Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O'Connell KM, Kaczorowski CC"
< "Q3TEA8-1","27470444","HP1BP3 expression determines maternal behavior and offspring survival.","Genes, brain, and behavior","2016 Sep","Garfinkel BP, Arad S, Neuner SM, Netser S, Wagner S, Kaczorowski CC, Rosen CJ, Gal M, Soreq H, Orly J"
< "Q3TEA8-1","26976970","Heterochromatin Protein 1 Binding Protein 3 Expression as a Candidate Marker of Intrinsic 5-Fluorouracil Resistance.","Anticancer research","2016 Mar","Hadac JN, Miller DD, Grimes IC, Clipson L, Newton MA, Schelman WR, Halberg RB"
< "Q3TEA8-1","26402843","Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.","Endocrinology","2015 Dec","Garfinkel BP, Arad S, Le PT, Bustin M, Rosen CJ, Gabet Y, Orly J"
< "Q3TEA8-1","25662603","HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth.","Nucleic acids research","2015 Feb 27","Garfinkel BP, Melamed-Book N, Anuka E, Bustin M, Orly J"
---
> "Q8BRT1-1","28069833","Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes.","Journal of cell science","2017 Feb 15","Shahbazi MN, Pena-Jimenez D, Antonucci F, Drosten M, Perez-Moreno M"
2538a2776,2778
> "Q9D9R7-1","16488114","Male-biased expression of X-chromosomal DM domain-less Dmrt8 genes in the mouse.","Genomics","2006 Aug","Veith AM, Klattig J, Dettai A, Schmidt C, Englert C, Volff JN"
> "Q01405-1","30065114","Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.","Proceedings of the National Academy of Sciences of the United States of America","2018 Aug 14","Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D"
> "Q01405-1","28259758","Huntingtin-associated protein-1 (HAP1) regulates endocytosis and interacts with multiple trafficking-related proteins.","Cellular signalling","2017 Jul","Mackenzie KD, Lim Y, Duffield MD, Chataway T, Zhou XF, Keating DJ"
2540a2781,2782
> "Q3UTY6-1","21880733","ADAMTSL6beta protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.","The Journal of biological chemistry","2011 Nov 4","Saito M, Kurokawa M, Oda M, Oshima M, Tsutsui K, Kosaka K, Nakao K, Ogawa M, Manabe R, Suda N, Ganjargal G, Hada Y, Noguchi T, Teranaka T, Sekiguchi K, Yoneda T, Tsuji T"
> "Q3UTY6-1","19940141","ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation.","The Journal of biological chemistry","2010 Feb 12","Tsutsui K, Manabe R, Yamada T, Nakano I, Oguri Y, Keene DR, Sengle G, Sakai LY, Sekiguchi K"
2542a2785
> "Q5DTV4-1","18178554","A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.","The Journal of biological chemistry","2008 Mar 7","Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE, Fu M"
2543a2787
> "Q922Y1-1","15944415","A novel protein specifically interacting with Homer2 regulates ubiquitin-proteasome systems.","Journal of biochemistry","2005 May","Ishibashi T, Ogawa S, Hashiguchi Y, Inoue Y, Udo H, Ohzono H, Kato A, Minakami R, Sugiyama H"
2544a2789,2794
> "Q6NZL8-1","20042401","SCUBE1, a novel developmental gene involved in renal regeneration and repair.","Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association","2010 May","Zhuang J, Deane JA, Yang RB, Li J, Ricardo SD"
> "Q6NZL8-1","19101956","Scube1 is expressed during facial development in the mouse.","Journal of experimental zoology. Part B, Molecular and developmental evolution","2009 Jul 15","Xavier GM, Sharpe PT, Cobourne MT"
> "Q6NZL8-1","18303018","Domain and functional analysis of a novel platelet-endothelial cell surface protein, SCUBE1.","The Journal of biological chemistry","2008 May 2","Tu CF, Yan YT, Wu SY, Djoko B, Tsai MT, Cheng CJ, Yang RB"
> "Q6AW69-1","29016873","Cgnl1, an endothelial junction complex protein, regulates GTPase mediated angiogenesis.","Cardiovascular research","2017 Dec 1","Chrifi I, Hermkens D, Brandt MM, van Dijk CGM, Burgisser PE, Haasdijk R, Pei J, van de Kamp EHM, Zhu C, Blonden L, Kros JM, Duncker DJ, Duckers HJ, Cheng C"
> "Q6AW69-1","15292197","JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.","The Journal of biological chemistry","2004 Oct 29","Ohnishi H, Nakahara T, Furuse K, Sasaki H, Tsukita S, Furuse M"
> "Q8C0P7-1","27343429","The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability.","The international journal of biochemistry &amp; cell biology","2016 Oct","Koidl S, Eisenhardt N, Fatouros C, Droescher M, Chaugule VK, Pichler A"
2546,2553c2796
< "O35732-1","29191940","Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation.","American journal of physiology. Gastrointestinal and liver physiology","2018 Mar 1","Gehrke N, Nagel M, Straub BK, Worns MA, Schuchmann M, Galle PR, Schattenberg JM"
< "O35732-1","29099934","A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1beta Release in Response to a Pathogenic Fungus.","The Journal of infectious diseases","2018 Jan 4","Ketelut-Carneiro N, Ghosh S, Levitz SM, Fitzgerald KA, da Silva JS"
< "O35732-1","28850249","Deletion of c-FLIP from CD11b(hi) Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis.","American journal of respiratory cell and molecular biology","2018 Jan","McCubbrey AL, Barthel L, Mohning MP, Redente EF, Mould KJ, Thomas SM, Leach SM, Danhorn T, Gibbings SL, Jakubzick CV, Henson PM, Janssen WJ"
< "O35732-1","29107687","MiR-150 deficiency ameliorated hepatosteatosis and insulin resistance in nonalcoholic fatty liver disease via targeting CASP8 and FADD-like apoptosis regulator.","Biochemical and biophysical research communications","2017 Dec 16","Zhuge B, Li G"
< "O35732-1","28218919","Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.","Nature medicine","2017 Apr","Wang PX, Ji YX, Zhang XJ, Zhao LP, Yan ZZ, Zhang P, Shen LJ, Yang X, Fang J, Tian S, Zhu XY, Gong J, Zhang X, Wei QF, Wang Y, Li J, Wan L, Xie Q, She ZG, Wang Z, Huang Z, Li H"
< "Q3UUG6-1","24729547","A dominant mutation in the stereocilia-expressing gene TBC1D24 is a probable cause for nonsyndromic hearing impairment.","Human mutation","2014 Jul","Zhang L, Hu L, Chai Y, Pang X, Yang T, Wu H"
< "Q3UUG6-1","20797691","A focal epilepsy and intellectual disability syndrome is due to a mutation in TBC1D24.","American journal of human genetics","2010 Sep 10","Corbett MA, Bahlo M, Jolly L, Afawi Z, Gardner AE, Oliver KL, Tan S, Coffey A, Mulley JC, Dibbens LM, Simri W, Shalata A, Kivity S, Jackson GD, Berkovic SF, Gecz J"
< "Q3UUG6-1","20727515","TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy.","American journal of human genetics","2010 Sep 10","Falace A, Filipello F, La Padula V, Vanni N, Madia F, De Pietri Tonelli D, de Falco FA, Striano P, Dagna Bricarelli F, Minetti C, Benfenati F, Fassio A, Zara F"
---
> "Q2WF71-1","18585462","Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth.","Molecular and cellular neurosciences","2008 Sep","Wang PY, Seabold GK, Wenthold RJ"
2558,2560d2800
< "Q80U16-1","27269051","Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.","eLife","2016 Jun 8","Zhao B, Wu Z, Muller U"
< "Q80U16-1","25588844","Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.","Journal of cell science","2015 Mar 1","Gao K, Tang W, Li Y, Zhang P, Wang D, Yu L, Wang C, Wu D"
< "Q8R4G0-1","11906208","Laminets: laminin- and netrin-related genes expressed in distinct neuronal subsets.","Molecular and cellular neurosciences","2002 Mar","Yin Y, Miner JH, Sanes JR"
2570a2811
> "Q8CI32-1","15603737","BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.","Neuron","2004 Dec 16","Kalia SK, Lee S, Smith PD, Liu L, Crocker SJ, Thorarinsdottir TE, Glover JR, Fon EA, Park DS, Lozano AM"
2577a2819
> "Q9D9R0-1","28476934","The Ubiquitin Ligase RNF125 Targets Innate Immune Adaptor Protein TRIM14 for Ubiquitination and Degradation.","Journal of immunology (Baltimore, Md. : 1950)","2017 Jun 15","Jia X, Zhou H, Wu C, Wu Q, Ma S, Wei C, Cao Y, Song J, Zhong H, Zhou Z, Wang J"
2579a2822,2823
> "P41438-1","15579899","Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates.","The Journal of biological chemistry","2005 Feb 18","Liu M, Ge Y, Cabelof DC, Aboukameel A, Heydari AR, Mohammad R, Matherly LH"
> "P41438-1","12832086","Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility.","Biochimica et biophysica acta","2003 Jun 27","Zhao R, Wang Y, Gao F, Goldman ID"
2590a2835,2840
> "Q9R045-1","28890470","Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction.","Circulation journal : official journal of the Japanese Circulation Society","2018 Jan 25","Tian Z, Miyata K, Morinaga J, Horiguchi H, Kadomatsu T, Endo M, Zhao J, Zhu S, Sugizaki T, Sato M, Terada K, Okumura T, Murohara T, Oike Y"
> "E9QAM5-1","23525231","THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation.","Molecular endocrinology (Baltimore, Md.)","2013 May","Katano-Toki A, Satoh T, Tomaru T, Yoshino S, Ishizuka T, Ishii S, Ozawa A, Shibusawa N, Tsuchiya T, Saito T, Shimizu H, Hashimoto K, Okada S, Yamada M, Mori M"
> "Q9D856-1","15322118","The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells.","The Journal of biological chemistry","2004 Dec 3","Wang F, Kim BE, Petris MJ, Eide DJ"
> "Q04646-1","25633594","FXYD2, a gamma subunit of Na(+), K(+)-ATPase, maintains persistent mechanical allodynia induced by inflammation.","Cell research","2015 Mar","Wang F, Cai B, Li KC, Hu XY, Lu YJ, Wang Q, Bao L, Zhang X"
> "Q04646-1","23344951","Hyperplasia of pancreatic beta cells and improved glucose tolerance in mice deficient in the FXYD2 subunit of Na,K-ATPase.","The Journal of biological chemistry","2013 Mar 8","Arystarkhova E, Liu YB, Salazar C, Stanojevic V, Clifford RJ, Kaplan JH, Kidder GM, Sweadner KJ"
> "Q04646-1","22253804","Regulation of the Na,K-ATPase gamma-subunit FXYD2 by Runx1 and Ret signaling in normal and injured non-peptidergic nociceptive sensory neurons.","PloS one","2012","Venteo S, Bourane S, Mechaly I, Sar C, Abdel Samad O, Puech S, Blostein R, Valmier J, Pattyn A, Carroll P"
2592a2843,2844
> "Q6PDG8-1","22665492","Mon1a protein acts in trafficking through the secretory apparatus.","The Journal of biological chemistry","2012 Jul 20","Bagley DC, Paradkar PN, Kaplan J, Ward DM"
> "Q6PDG8-1","20305638","Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.","Nature","2010 Apr 1","Kinchen JM, Ravichandran KS"
2598a2851,2853
> "P54310-1","30086728","Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice.","BMC cancer","2018 Aug 7","Xu M, Chang HH, Jung X, Moro A, Chou CEN, King J, Hines OJ, Sinnett-Smith J, Rozengurt E, Eibl G"
> "P54310-1","29232702","Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice.","PLoS genetics","2017 Dec","Xia B, Cai GH, Yang H, Wang SP, Mitchell GA, Wu JW"
> "P54310-1","28851734","Cardiac overexpression of perilipin 2 induces dynamic steatosis: prevention by hormone-sensitive lipase.","American journal of physiology. Endocrinology and metabolism","2017 Dec 1","Ueno M, Suzuki J, Hirose M, Sato S, Imagawa M, Zenimaru Y, Takahashi S, Ikuyama S, Koizumi T, Konoshita T, Kraemer FB, Ishizuka T"
2601a2857
> "Q8CHK3-1","21746835","Congenital hydrocephalus in genetically engineered mice.","Veterinary pathology","2012 Jan","Vogel P, Read RW, Hansen GM, Payne BJ, Small D, Sands AT, Zambrowicz BP"
2610a2867,2871
> "Q9Z0S6-1","29129401","Deletion of claudin-10 rescues claudin-16-deficient mice from hypomagnesemia and hypercalciuria.","Kidney international","2018 Mar","Breiderhoff T, Himmerkus N, Drewell H, Plain A, Gunzel D, Mutig K, Willnow TE, Muller D, Bleich M"
> "Q9Z0S6-1","28771254","Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX syndrome.","Genetics in medicine : official journal of the American College of Medical Genetics","2018 Feb","Hadj-Rabia S, Brideau G, Al-Sarraj Y, Maroun RC, Figueres ML, Leclerc-Mercier S, Olinger E, Baron S, Chaussain C, Nochy D, Taha RZ, Knebelmann B, Joshi V, Curmi PA, Kambouris M, Vargas-Poussou R, Bodemer C, Devuyst O, Houillier P, El-Shanti H"
> "Q9Z0S6-1","29145406","The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes.","PloS one","2017","Perez EC, Xander P, Laurindo MFL, Novaes E Brito RR, Vivanco BC, Mortara RA, Mariano M, Lopes JD, Keller AC"
> "Q9Z0S6-1","26340953","Claudin-3, claudin-7, and claudin-10 show different distribution patterns during decidualization and trophoblast invasion in mouse and human.","Histochemistry and cell biology","2015 Dec","Schumann S, Buck VU, Classen-Linke I, Wennemuth G, Grummer R"
> "Q9Z0S6-1","14698084","Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.","Hearing research","2004 Jan","Kitajiri SI, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita S"
2611a2873,2874
> "Q9D7Q1-1","26079949","Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.","Clinical immunology (Orlando, Fla.)","2015 Oct","Canto E, Espejo C, Costa C, Montalban X, Comabella M"
> "Q9D7Q1-1","23685110","Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice.","The American journal of pathology","2013 Jul","Kitamoto S, Egashira K, Ichiki T, Han X, McCurdy S, Sakuda S, Sunagawa K, Boisvert WA"
2618,2619d2880
< "Q99PN3-1","29203640","Transforming Growth Factor beta-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC.","Molecular and cellular biology","2018 Mar 1","Nakagawa T, Hosogane M, Nakagawa M, Morohoshi A, Funayama R, Nakayama K"
< "Q99PN3-1","25763818","TRIM26 negatively regulates interferon-beta production and antiviral response through polyubiquitination and degradation of nuclear IRF3.","PLoS pathogens","2015 Mar","Wang P, Zhao W, Zhao K, Zhang L, Gao C"
2628,2629d2888
< "Q9JLN6-1","28707394","CD19 regulates ADAM28-mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells.","Journal of cellular and molecular medicine","2017 Dec","Zhang Y, Zhu G, Xiao H, Liu X, Han G, Chen G, Hou C, Shen B, Li Y, Ma N, Wang R"
< "Q9JLN6-1","11724793","The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1.","The Journal of biological chemistry","2002 Feb 1","Bridges LC, Tani PH, Hanson KR, Roberts CM, Judkins MB, Bowditch RD"
2648,2649d2906
< "Q99MU3-1","30669342","ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis.","International journal of molecular sciences","2019 Jan 18","Zhang X, Gao X, Hu J, Xie Y, Zuo Y, Xu H, Zhu S"
< "Q99MU3-1","28960389","The Other Face of an Editor: ADAR1 Functions in Editing-Independent Ways.","BioEssays : news and reviews in molecular, cellular and developmental biology","2017 Nov","Licht K, Jantsch MF"
2651,2653c2908,2910
< "B1AXP6-1","22688586","Cryptogenic organizing pneumonia in Tomm5(-/-) mice.","Veterinary pathology","2013 Jan","Vogel P, Read RW, Rehg JE, Hansen GM"
< "Q80TJ1-1","28883501","CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.","Scientific reports","2017 Sep 7","van Keimpema L, Kooistra R, Toonen RF, Verhage M"
< "Q80TJ1-1","16506193","Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain.","The Journal of comparative neurology","2006 Apr 20","Sadakata T, Itakura M, Kozaki S, Sekine Y, Takahashi M, Furuichi T"
---
> "Q61069-1","30545366","USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages.","Lipids in health and disease","2018 Dec 13","Ruuth M, Soronen J, Kaiharju E, Merikanto K, Perttila J, Metso J, Lee-Rueckert M, Taskinen MR, Kovanen PT, Oorni K, Olkkonen VM, Jauhiainen MS, Laurila PP"
> "Q61069-1","29871931","Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1).","The Journal of biological chemistry","2018 Jul 20","Noguchi K, Dincman TA, Dalton AC, Howley BV, McCall BJ, Mohanty BK, Howe PH"
> "Q9Z2H2-1","29079565","Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca(2+)/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development.","Journal of the American Heart Association","2017 Oct 27","Chakravarti B, Yang J, Ahlers-Dannen KE, Luo Z, Flaherty HA, Meyerholz DK, Anderson ME, Fisher RA"
2663c2920,2923
< "P63015-1","16464444","Analysis of Pax6 expression using a BAC transgene reveals the presence of a paired-less isoform of Pax6 in the eye and olfactory bulb.","Developmental biology","2006 Apr 15","Kim J, Lauderdale JD"
---
> "Q9CYH2-1","26438880","Adipocyte-derived PAMM suppresses macrophage inflammation by inhibiting MAPK signalling.","The Biochemical journal","2015 Dec 15","Guo F, He H, Fu ZC, Huang S, Chen T, Papasian CJ, Morse LR, Xu Y, Battaglino RA, Yang XF, Jiang Z, Xin HB, Fu M"
> "Q9CYH2-1","19951071","PAMM: a redox regulatory protein that modulates osteoclast differentiation.","Antioxidants &amp; redox signaling","2010 Jul 1","Xu Y, Morse LR, da Silva RA, Odgren PR, Sasaki H, Stashenko P, Battaglino RA"
> "P19973-1","27555448","Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells.","Nature communications","2016 Aug 24","Wu JL, Wu HY, Tsai DY, Chiang MF, Chen YJ, Gao S, Lin CC, Lin CH, Khoo KH, Chen YJ, Lin KI"
> "P19973-1","26554018","Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis.","Proceedings of the National Academy of Sciences of the United States of America","2015 Nov 24","Hwang SH, Jung SH, Lee S, Choi S, Yoo SA, Park JH, Hwang D, Shim SC, Sabbagh L, Kim KJ, Park SH, Cho CS, Kim BS, Leng L, Montgomery RR, Bucala R, Chung YJ, Kim WU"
2664a2925
> "P59113-1","28954813","Kindlin supports platelet integrin alphaIIbbeta3 activation by interacting with paxillin.","Journal of cell science","2017 Nov 1","Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, Hu Y, Zhang Y, Schulte ML, Jin C, Wang J, White GC, Xu Z, Ma YQ"
2671a2933
> "Q148V7-1","29514919","The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution.","The Journal of cell biology","2018 May 7","Sobajima T, Yoshimura SI, Maeda T, Miyata H, Miyoshi E, Harada A"
2672a2935
> "Q9JLL3-1","29237753","Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney.","Proceedings of the National Academy of Sciences of the United States of America","2017 Dec 26","Schutgens F, Rookmaaker MB, Blokzijl F, van Boxtel R, Vries R, Cuppen E, Verhaar MC, Clevers H"
2676c2939
< "Q8K214-1","23207902","Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.","Molecular and cellular biology","2013 Feb","Yasunaga S, Ohtsubo M, Ohno Y, Saeki K, Kurogi T, Tanaka-Okamoto M, Ishizaki H, Shirai M, Mihara K, Brock HW, Miyoshi J, Takihara Y"
---
> "Q924W7-1","29650351","Overexpression of ST5, an activator of Ras, has no effect on beta-cell proliferation in adult mice.","Molecular metabolism","2018 May","Ou K, Zhang J, Jiao Y, Wang ZV, Scherer P, Kaestner KH"
2682,2684d2944
< "Q8VE91-4","27511895","FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga.","The Journal of infectious diseases","2016 Oct 15","Chiramel AI, Dougherty JD, Nair V, Robertson SJ, Best SM"
< "Q8VE91-4","26040720","Regulation of endoplasmic reticulum turnover by selective autophagy.","Nature","2015 Jun 18","Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, Kurth I, Hubner CA, Dikic I"
< "Q8VE91-4","19838196","Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy.","Nature genetics","2009 Nov","Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nurnberg G, Nurnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hubner CA"
2700a2961
> "Q9ERD8-1","11722847","Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans.","Gene","2001 Nov 14","Korenbaum E, Olski TM, Noegel AA"
2704,2706c2965,2968
< "P46737-1","23246432","Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.","Molecular cell","2013 Jan 24","Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J"
< "Q9EQZ6-1","30048476","Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice.","PloS one","2018","Aesoy R, Muwonge H, Asrud KS, Sabir M, Witsoe SL, Bjornstad R, Kopperud RK, Hoivik EA, Doskeland SO, Bakke M"
< "Q9EQZ6-1","12401793","Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis.","The Journal of biological chemistry","2002 Dec 27","Fujimoto K, Shibasaki T, Yokoi N, Kashima Y, Matsumoto M, Sasaki T, Tajima N, Iwanaga T, Seino S"
---
> "Q6NXH3-1","14612417","The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.","Molecular and cellular biology","2003 Dec","Hsu LC, Liu S, Abedinpour F, Beech RD, Lahti JM, Kidd VJ, Greenspan JA, Yeung CY"
> "Q8CH20-1","17342728","A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family.","Molecular reproduction and development","2008 Feb","Hansen MA, Nielsen JE, Retelska D, Larsen N, Leffers H"
> "Q8CH20-1","15286030","Characterization of a novel postacrosomal perinuclear theca-specific protein, CYPT1.","Biology of reproduction","2004 Dec","Kitamura K, Iguchi N, Kaneko Y, Tanaka H, Nishimune Y"
> "Q4LDD4-1","28132686","Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.","American journal of human genetics","2017 Feb 2","Carrat GR, Hu M, Nguyen-Tu MS, Chabosseau P, Gaulton KJ, van de Bunt M, Siddiq A, Falchi M, Thurner M, Canouil M, Pattou F, Leclerc I, Pullen TJ, Cane MC, Prabhala P, Greenwald W, Schulte A, Marchetti P, Ibberson M, MacDonald PE, Manning Fox JE, Gloyn AL, Froguel P, Solimena M, McCarthy MI, Rutter GA"
2711a2974,2975
> "Q64373-1","29704100","Downregulation of miR-34a promotes endothelial cell growth and suppresses apoptosis in atherosclerosis by regulating Bcl-2.","Heart and vessels","2018 Oct","Su G, Sun G, Liu H, Shu L, Liang Z"
> "Q64373-1","30261081","Infection with flaviviruses requires BCLXL for cell survival.","PLoS pathogens","2018 Sep","Suzuki T, Okamoto T, Katoh H, Sugiyama Y, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Fukuhara T, Ikawa M, Satoh T, Yoshio S, Suzuki R, Saijo M, Huang DCS, Kanto T, Akira S, Matsuura Y"
2722,2723d2985
< "Q99KW3-3","28209736","Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Mar 29","Kazmierczak M, Kazmierczak P, Peng AW, Harris SL, Shah P, Puel JL, Lenoir M, Franco SJ, Schwander M"
< "Q99KW3-3","23789641","R1 motif is the major actin-binding domain of TRIOBP-4.","Biochemistry","2013 Aug 6","Bao J, Bielski E, Bachhawat A, Taha D, Gunther LK, Thirumurugan K, Kitajiri S, Sakamoto T"
2734,2735d2995
< "Q924A2-4","29382756","Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.","Proceedings of the National Academy of Sciences of the United States of America","2018 Feb 13","Tan Q, Brunetti L, Rousseaux MWC, Lu HC, Wan YW, Revelli JP, Liu Z, Goodell MA, Zoghbi HY"
< "Q924A2-4","12393275","CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons.","Brain research. Molecular brain research","2002 Oct 15","Lee CJ, Chan WI, Cheung M, Cheng YC, Appleby VJ, Orme AT, Scotting PJ"
2738a2999,3005
> "B1AXP6-1","22688586","Cryptogenic organizing pneumonia in Tomm5(-/-) mice.","Veterinary pathology","2013 Jan","Vogel P, Read RW, Rehg JE, Hansen GM"
> "Q925T6-1","29170386","Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages.","Nature communications","2017 Nov 23","Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall MA, Fisher RP, Hu X, Chinenov Y, Rogatsky I"
> "Q925T6-1","28978486","GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.","Cell reports","2017 Oct 3","Pfennig S, Foss F, Bissen D, Harde E, Treeck JC, Segarra M, Acker-Palmer A"
> "Q925T6-1","28063882","Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880.","Behavioural brain research","2017 Mar 15","Han M, Mejias R, Chiu SL, Rose R, Adamczyk A, Huganir R, Wang T"
> "Q925T6-1","27941904","The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility.","Scientific reports","2016 Dec 12","Wang Y, Wu Z, Luo H, Peng J, Raelson J, Ehret GB, Munroe PB, Stoyanova E, Qin Z, Cloutier G, Bradley WE, Wu T, Shen JZ, Hu S, Wu J"
> "Q925T6-1","15507123","GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2004 Nov","Nakata A, Ito T, Nagata M, Hori S, Sekimizu K"
> "Q925T6-1","11983858","Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1.","Proceedings of the National Academy of Sciences of the United States of America","2002 May 14","Bladt F, Tafuri A, Gelkop S, Langille L, Pawson T"
2740a3008
> "Q91V51-1","15890843","Tubulin polyglutamylase enzymes are members of the TTL domain protein family.","Science (New York, N.Y.)","2005 Jun 17","Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Edde B"
2746,2747d3013
< "Q8CBQ5-1","16949365","Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.","Molecular cell","2006 Sep 1","Jones DR, Bultsma Y, Keune WJ, Halstead JR, Elouarrat D, Mohammed S, Heck AJ, D'Santos CS, Divecha N"
< "Q8CBQ5-1","12011096","NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway.","The Journal of biological chemistry","2002 Jul 26","Mora S, Durham PL, Smith JR, Russo AF, Jeromin A, Pessin JE"
2751,2752d3016
< "O35618-1","30012555","Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy.","Genes &amp; development","2018 Aug 1","Van Alstyne M, Simon CM, Sardi SP, Shihabuddin LS, Mentis GZ, Pellizzoni L"
< "O35618-1","24013503","Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.","Genes &amp; development","2013 Sep 1","Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ, Guccione E"
2761a3026,3027
> "Q8BJ66-1","15555553","Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells.","Biochemical and biophysical research communications","2004 Dec 24","Shibata Y, Tsukazaki T, Hirata K, Xin C, Yamaguchi A"
> "Q8BJ66-1","15261838","Bono1: a gene associated with regions of deposition of bone and dentine.","Gene expression patterns : GEP","2004 Sep","James MJ, Jarvinen E, Thesleff I"
2769,2771d3034
< "Q9CQJ7-1","28658604","Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.","Cellular signalling","2017 Oct","Wei R, Li B, Guo J, Li M, Zhu R, Yang X, Gao R"
< "Q9CQJ7-1","28516917","Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.","Nature communications","2017 May 18","Nabti I, Grimes R, Sarna H, Marangos P, Carroll J"
< "Q9CQJ7-1","27524416","mTOR promotes pituitary tumor development through activation of PTTG1.","Oncogene","2017 Feb 16","Chen R, Duan J, Li L, Ma Q, Sun Q, Ma J, Li C, Zhou X, Chen H, Jing Y, Zhao S, Wu X, Zhang H"
2778,2780c3041
< "P0DPB4-1","27979964","Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.","The Journal of biological chemistry","2017 Feb 10","Martin PM, Cifuentes-Diaz C, Devaux J, Garcia M, Bureau J, Thomasseau S, Klingler E, Girault JA, Goutebroze L"
< "P0DPB4-1","25950943","CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.","Journal of neurochemistry","2015 Aug","Papandreou MJ, Vacher H, Fache MP, Klingler E, Rueda-Boroni F, Ferracci G, Debarnot C, Piperoglou C, Garcia Del Cano G, Goutebroze L, Dargent B"
< "P0DPB4-1","25953347","The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.","Development (Cambridge, England)","2015 Jun 1","Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chedotal A, Girault JA, Goutebroze L"
---
> "Q8VDD8-1","20308062","Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulin.","The Journal of biological chemistry","2010 May 28","Monfregola J, Napolitano G, D'Urso M, Lappalainen P, Ursini MV"
2787,2789d3047
< "O08715-1","29388469","Akap1 genetic deletion increases the severity of hyperoxia-induced acute lung injury in mice.","American journal of physiology. Lung cellular and molecular physiology","2018 May 1","Narala VR, Fukumoto J, Hernandez-Cuervo H, Patil SS, Krishnamurthy S, Breitzig M, Galam L, Soundararajan R, Lockey RF, Kolliputi N"
< "O08715-1","28569781","Mitochondrial AKAP1 supports mTOR pathway and tumor growth.","Cell death &amp; disease","2017 Jun 1","Rinaldi L, Sepe M, Delle Donne R, Conte K, Arcella A, Borzacchiello D, Amente S, De Vita F, Porpora M, Garbi C, Oliva MA, Procaccini C, Faicchia D, Matarese G, Zito Marino F, Rocco G, Pignatiello S, Franco R, Insabato L, Majello B, Feliciello A"
< "O08715-1","28500286","A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.","Scientific reports","2017 May 12","Brackley AD, Gomez R, Guerrero KA, Akopian AN, Glucksman MJ, Du J, Carlton SM, Jeske NA"
2805,2807c3063,3064
< "Q00196-1","26993806","Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2.","Proceedings of the National Academy of Sciences of the United States of America","2016 Apr 5","Hodson DJ, Shaffer AL, Xiao W, Wright GW, Schmitz R, Phelan JD, Yang Y, Webster DE, Rui L, Kohlhammer H, Nakagawa M, Waldmann TA, Staudt LM"
< "Q00196-1","26361887","NF-kappaB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells.","European journal of immunology","2015 Dec","Kilzheimer M, Quandt J, Langhans J, Weihrich P, Wirth T, Brunner C"
< "Q00196-1","26016715","Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis.","Diabetes","2015 Sep","Clarke JD, Dzierlenga AL, Nelson NR, Li H, Werts S, Goedken MJ, Cherrington NJ"
---
> "Q91VJ1-1","19158676","AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.","Nature","2009 Mar 26","Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES"
> "Q91VJ1-1","19158675","AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.","Nature","2009 Mar 26","Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA"
2819,2824d3075
< "Q3UJD6-1","29901692","Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling.","Endocrinology","2018 Aug 1","Coyne ES, Bedard N, Wykes L, Stretch C, Jammoul S, Li S, Zhang K, Sladek RS, Bathe OF, Jagoe RT, Posner BI, Wing SS"
< "Q3UJD6-1","28886438","Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor beta and increases skeletal muscle mass in young female mice.","The Journal of nutritional biochemistry","2017 Nov","Ogawa M, Kitano T, Kawata N, Sugihira T, Kitakaze T, Harada N, Yamaji R"
< "Q3UJD6-1","26048142","Inactivation of the ubiquitin-specific protease 19 deubiquitinating enzyme protects against muscle wasting.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2015 Sep","Bedard N, Jammoul S, Moore T, Wykes L, Hallauer PL, Hastings KE, Stretch C, Baracos V, Chevalier S, Plourde M, Coyne E, Wing SS"
< "Q3UJD6-1","25568336","USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling.","Molecular biology of the cell","2015 Mar 1","Wiles B, Miao M, Coyne E, Larose L, Cybulsky AV, Wing SS"
< "Q3UJD6-1","21971047","17beta-estradiol represses myogenic differentiation by increasing ubiquitin-specific peptidase 19 through estrogen receptor alpha.","The Journal of biological chemistry","2011 Dec 2","Ogawa M, Yamaji R, Higashimura Y, Harada N, Ashida H, Nakano Y, Inui H"
< "Q3UJD6-1","19015242","USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.","Molecular and cellular biology","2009 Jan","Lu Y, Adegoke OA, Nepveu A, Nakayama KI, Bedard N, Cheng D, Peng J, Wing SS"
2826a3078,3079
> "Q9DBH0-1","29925997","The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR.","Nature immunology","2018 Jul","Aki D, Li H, Zhang W, Zheng M, Elly C, Lee JH, Zou W, Liu YC"
> "Q9DCT8-1","29662084","HOXA9 inhibits HIF-1alpha-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development.","Nature communications","2018 Apr 16","Zhou L, Wang Y, Zhou M, Zhang Y, Wang P, Li X, Yang J, Wang H, Ding Z"
2827a3081,3085
> "Q504P2-1","15238421","KLRL1, a novel killer cell lectinlike receptor, inhibits natural killer cell cytotoxicity.","Blood","2004 Nov 1","Han Y, Zhang M, Li N, Chen T, Zhang Y, Wan T, Cao X"
> "P70451-1","27401557","HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer.","Genes &amp; development","2016 Jul 1","Fan G, Zhang S, Gao Y, Greer PA, Tonks NK"
> "P70451-1","27226326","The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm.","Development (Cambridge, England)","2016 Jul 1","Alvau A, Battistone MA, Gervasi MG, Navarrete FA, Xu X, Sanchez-Cardenas C, De la Vega-Beltran JL, Da Ros VG, Greer PA, Darszon A, Krapf D, Salicioni AM, Cuasnicu PS, Visconti PE"
> "P70451-1","25237066","Oncogenic properties of a spermatogenic meiotic variant of fer kinase expressed in somatic cells.","Cancer research","2014 Nov 15","Yaffe E, Hikri E, Elkis Y, Cohen O, Segal A, Makovski A, Varvak A, Shpungin S, Nir U"
> "P70451-1","23589302","The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.","The Journal of biological chemistry","2013 May 31","Lennartsson J, Ma H, Wardega P, Pelka K, Engstrom U, Hellberg C, Heldin CH"
2829a3088
> "Q8BGU2-1","29784783","Postsynaptic delta1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.","Proceedings of the National Academy of Sciences of the United States of America","2018 Jun 5","Tao W, Diaz-Alonso J, Sheng N, Nicoll RA"
2831a3091,3093
> "Q5UAK0-3","26938916","Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.","PLoS genetics","2016 Mar","Lakisic G, Lebreton A, Pourpre R, Wendling O, Libertini E, Radford EJ, Le Guillou M, Champy MF, Wattenhofer-Donze M, Soubigou G, Ait-Si-Ali S, Feunteun J, Sorg T, Coppee JY, Ferguson-Smith AC, Cossart P, Bierne H"
> "Q5UAK0-3","17622490","Protein expression of the transcriptional regulator MI-ER1 alpha in adult mouse tissues.","Journal of molecular histology","2008 Feb","Thorne LB, McCarthy PL, Paterno GD, Gillespie LL"
> "Q5UAK0-3","16147882","Cloning and characterization of the mouse ortholog of mi-er1.","DNA sequence : the journal of DNA sequencing and mapping","2005 Jun","Thorne LB, Grant AL, Paterno GD, Gillespie LL"
2840,2845d3101
< "Q8K3J5-1","29750959","A BTB-ZF protein, ZNF131, is required for early B cell development.","Biochemical and biophysical research communications","2018 Jun 22","Iguchi T, Miyauchi E, Watanabe S, Masai H, Miyatake S"
< "Q8K3J5-1","28882591","The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.","Biochemical and biophysical research communications","2017 Nov 4","Robinson SC, Donaldson-Kabwe NS, Dvorkin-Gheva A, Longo J, He L, Daniel JM"
< "Q8K3J5-1","26136427","BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.","Journal of immunology (Baltimore, Md. : 1950)","2015 Aug 1","Iguchi T, Aoki K, Ikawa T, Taoka M, Taya C, Yoshitani H, Toma-Hirano M, Koiwai O, Isobe T, Kawamoto H, Masai H, Miyatake S"
< "Q8K3J5-1","20303951","Kaiso regulates Znf131-mediated transcriptional activation.","Experimental cell research","2010 Jun 10","Donaldson NS, Nordgaard CL, Pierre CC, Kelly KF, Robinson SC, Swystun L, Henriquez R, Graham M, Daniel JM"
< "Q8K3J5-1","17306895","Nuclear trafficking of the POZ-ZF protein Znf131.","Biochimica et biophysica acta","2007 Apr","Donaldson NS, Daniel Y, Kelly KF, Graham M, Daniel JM"
< "Q8K3J5-1","12163020","The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus.","Biochemical and biophysical research communications","2002 Aug 16","Trappe R, Buddenberg P, Uedelhoven J, Glaser B, Buck A, Engel W, Burfeind P"
2854,2857c3110,3111
< "Q9D2H6-1","30337366","Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites.","The Journal of biological chemistry","2018 Dec 14","Volkel S, Stielow B, Finkernagel F, Berger D, Stiewe T, Nist A, Suske G"
< "Q9D2H6-1","27191968","Transcription Factor SP2 Enhanced the Expression of Cd14 in Colitis-Susceptible C3H/HeJBir.","PloS one","2016","Zschemisch NH, Brusch I, Hambusch AS, Bleich A"
< "Q9D2H6-1","25793500","Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3.","PLoS genetics","2015 Mar","Volkel S, Stielow B, Finkernagel F, Stiewe T, Nist A, Suske G"
< "Q9D2H6-1","23293287","Neural development is dependent on the function of specificity protein 2 in cell cycle progression.","Development (Cambridge, England)","2013 Feb 1","Liang H, Xiao G, Yin H, Hippenmeyer S, Horowitz JM, Ghashghaei HT"
---
> "P97868-1","17470788","PACT is a negative regulator of p53 and essential for cell growth and embryonic development.","Proceedings of the National Academy of Sciences of the United States of America","2007 May 8","Li L, Deng B, Xing G, Teng Y, Tian C, Cheng X, Yin X, Yang J, Gao X, Zhu Y, Sun Q, Zhang L, Yang X, He F"
> "P97868-1","15617101","P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA.","Journal of cellular physiology","2005 Jul","Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW"
2858a3113
> "Q9Z1A1-1","23479643","Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.","Proceedings of the National Academy of Sciences of the United States of America","2013 Mar 26","Beetz C, Johnson A, Schuh AL, Thakur S, Varga RE, Fothergill T, Hertel N, Bomba-Warczak E, Thiele H, Nurnberg G, Altmuller J, Saxena R, Chapman ER, Dent EW, Nurnberg P, Audhya A"
2860a3116,3121
> "Q9JJT2-1","16497798","Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice.","Endocrinology","2006 May","Lindfors PH, Lindahl M, Rossi J, Saarma M, Airaksinen MS"
> "Q99N50-1","24284068","Slp2-a controls renal epithelial cell size through regulation of Rap-ezrin signaling independently of Rab27.","Journal of cell science","2014 Feb 1","Yasuda T, Fukuda M"
> "Q99N50-1","22767581","Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.","Molecular biology of the cell","2012 Aug","Yasuda T, Saegusa C, Kamakura S, Sumimoto H, Fukuda M"
> "Q99N50-1","20729199","Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.","The Journal of biological chemistry","2010 Oct 29","Pang ZP, Xu W, Cao P, Sudhof TC"
> "Q99N50-1","15543135","Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.","Nature cell biology","2004 Dec","Kuroda TS, Fukuda M"
> "Q99N50-1","11773082","The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.","The Journal of biological chemistry","2002 Mar 15","Kuroda TS, Fukuda M, Ariga H, Mikoshiba K"
2865,2866d3125
< "Q80TH2-3","26025865","FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy.","International journal of cardiology","2015 Sep 15","Rachmin I, Amsalem E, Golomb E, Beeri R, Gilon D, Fang P, Nechushtan H, Kay G, Guo M, Yiqing PL, Foo RS, Fisher DE, Razin E, Tshori S"
< "Q80TH2-3","26056141","Erbin is a novel substrate of the Sag-betaTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis.","The Journal of cell biology","2015 Jun 8","Xie CM, Wei D, Zhao L, Marchetto S, Mei L, Borg JP, Sun Y"
2876,2877c3135,3136
< "Q4KMM3-1","27036366","The antioxidant protein Oxr1 influences aspects of mitochondrial morphology.","Free radical biology &amp; medicine","2016 Jun","Wu Y, Davies KE, Oliver PL"
< "Q4KMM3-1","25753484","Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis.","Brain : a journal of neurology","2015 May","Liu KX, Edwards B, Lee S, Finelli MJ, Davies B, Davies KE, Oliver PL"
---
> "Q5D525-1","16328886","Identification of a new transcript specifically expressed in mouse spermatocytes: mmrp2.","Molecular biology reports","2005 Dec","Gu S, Hu J, Song P, Gong W, Guo M"
> "Q9QUK0-1","14605869","Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus.","Cell and tissue research","2004 Feb","Sassa T, Gomi H, Itohara S"
2881,2885c3140,3145
< "Q80YE7-1","29317503","ER-stress mobilization of death-associated protein kinase-1-dependent xenophagy counteracts mitochondria stress-induced epithelial barrier dysfunction.","The Journal of biological chemistry","2018 Mar 2","Lopes F, Keita AV, Saxena A, Reyes JL, Mancini NL, Al Rajabi A, Wang A, Baggio CH, Dicay M, van Dalen R, Ahn Y, Carneiro MBH, Peters NC, Rho JM, MacNaughton WK, Girardin SE, Jijon H, Philpott DJ, Soderholm JD, McKay DM"
< "Q80YE7-1","28731405","Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.","eLife","2017 Jul 21","McQueen J, Ryan TJ, McKay S, Marwick K, Baxter P, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJA, Grant SGN, McColl BW, Komiyama NH, Hardingham GE"
< "Q80YE7-1","28614711","DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific.","Cell reports","2017 Jun 13","Goodell DJ, Zaegel V, Coultrap SJ, Hell JW, Bayer KU"
< "Q80YE7-1","14530257","Antisense depletion of death-associated protein kinase promotes apoptosis.","The Journal of biological chemistry","2003 Dec 19","Jin Y, Gallagher PJ"
< "D3Z7P3-1","30472430","GLS1 Mutant Mice Display Moderate Alterations of Hippocampal Glutamatergic Neurotransmission Associated with Specific Adaptive Behavioral Changes.","Neuroscience","2019 Jan 1","Dutar P, Tolle V, Kervern M, Carcenac C, Carola V, Gross C, Savasta M, Darmon M, Masson J"
---
> "Q8CCE9-1","27621446","E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 27","Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, Gayte L, Casas F, Pessemesse L, Heuillet M, Bellvert F, Portais JC, Berthet C, Bernex F, Brivet M, Boutron A, Le Cam L, Sardet C"
> "Q8CCE9-1","27621431","E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 27","Goguet-Rubio P, Seyran B, Gayte L, Bernex F, Sutter A, Delpech H, Linares LK, Riscal R, Repond C, Rodier G, Kirsh O, Touhami J, Noel J, Vincent C, Pirot N, Pavlovic G, Herault Y, Sitbon M, Pellerin L, Sardet C, Lacroix M, Le Cam L"
> "Q8CCE9-1","25843721","The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions.","Cell reports","2015 Apr 14","Rodier G, Kirsh O, Baraibar M, Houles T, Lacroix M, Delpech H, Hatchi E, Arnould S, Severac D, Dubois E, Caramel J, Julien E, Friguet B, Le Cam L, Sardet C"
> "Q8CCE9-1","25843717","E4F1 is a master regulator of CHK1-mediated functions.","Cell reports","2015 Apr 14","Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G"
> "O54830-1","12399423","Two placental hormones are agonists in stimulating megakaryocyte growth and differentiation.","Endocrinology","2002 Nov","Zhou B, Lum HE, Lin J, Linzer DI"
> "O54830-1","12040023","Reactivation of a hematopoietic endocrine program of pregnancy contributes to recovery from thrombocytopenia.","Molecular endocrinology (Baltimore, Md.)","2002 Jun","Bhattacharyya S, Lin J, Linzer DI"
2905a3166,3167
> "Q62556-1","20208008","BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.","Journal of immunology (Baltimore, Md. : 1950)","2010 Apr 1","Smith IA, Knezevic BR, Ammann JU, Rhodes DA, Aw D, Palmer DB, Mather IH, Trowsdale J"
> "Q62556-1","19531472","The PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase: implications for the function of BTN1A1 in the mammary gland and other tissues.","The Journal of biological chemistry","2009 Aug 14","Jeong J, Rao AU, Xu J, Ogg SL, Hathout Y, Fenselau C, Mather IH"
2907d3168
< "P98083-1","30047409","Hyperglycaemia-induced epigenetic changes drive persistent cardiac dysfunction via the adaptor p66(Shc).","International journal of cardiology","2018 Oct 1","Costantino S, Paneni F, Mitchell K, Mohammed SA, Hussain S, Gkolfos C, Berrino L, Volpe M, Schwarzwald C, Luscher TF, Cosentino F"
2912,2913d3172
< "Q8BH60-1","20958966","PIST regulates the intracellular trafficking and plasma membrane expression of cadherin 23.","BMC cell biology","2010 Oct 19","Xu Z, Oshima K, Heller S"
< "Q8BH60-1","12149515","Lack of acrosome formation in mice lacking a Golgi protein, GOPC.","Proceedings of the National Academy of Sciences of the United States of America","2002 Aug 20","Yao R, Ito C, Natsume Y, Sugitani Y, Yamanaka H, Kuretake S, Yanagida K, Sato A, Toshimori K, Noda T"
2920a3180,3183
> "Q7TNK1-1","29298325","Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype.","PloS one","2018","Xu P, Morrison JP, Foley JF, Stumpo DJ, Ward T, Zeldin DC, Blackshear PJ"
> "Q7TNK1-1","14701801","Restricted expression and photic induction of a novel mouse regulatory factor X4 transcript in the suprachiasmatic nucleus.","The Journal of biological chemistry","2004 Mar 12","Araki R, Takahashi H, Fukumura R, Sun F, Umeda N, Sujino M, Inouye ST, Saito T, Abe M"
> "Q7TNK1-1","12925582","Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4.","Development (Cambridge, England)","2003 Oct","Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL, Zeldin DC"
> "Q6PE87-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
2932,2934c3195,3199
< "G5E8K5-1","30562487","Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.","Developmental biology","2019 Feb 1","Rasiah PK, Maddala R, Bennett V, Rao PV"
< "G5E8K5-1","30046097","Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling.","Translational psychiatry","2018 Jul 25","Garza JC, Qi X, Gjeluci K, Leussis MP, Basu H, Reis SA, Zhao WN, Piguel NH, Penzes P, Haggarty SJ, Martens GJ, Poelmans G, Petryshen TL"
< "G5E8K5-1","29963618","Simultaneous Ablation of Neuronal Neurofascin and Ankyrin G in Young and Adult Mice Reveals Age-Dependent Increase in Nodal Stability in Myelinated Axons and Differential Effects on the Lifespan.","eNeuro","2018 May-Jun","Taylor AM, Shi Q, Bhat MA"
---
> "Q5HZI1-1","15123706","Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP.","The Journal of biological chemistry","2004 Jul 9","Nouet S, Amzallag N, Li JM, Louis S, Seitz I, Cui TX, Alleaume AM, Di Benedetto M, Boden C, Masson M, Strosberg AD, Horiuchi M, Couraud PO, Nahmias C"
> "Q8CBQ5-1","16949365","Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.","Molecular cell","2006 Sep 1","Jones DR, Bultsma Y, Keune WJ, Halstead JR, Elouarrat D, Mohammed S, Heck AJ, D'Santos CS, Divecha N"
> "Q8CBQ5-1","12011096","NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway.","The Journal of biological chemistry","2002 Jul 26","Mora S, Durham PL, Smith JR, Russo AF, Jeromin A, Pessin JE"
> "P47857-1","29655163","Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms.","Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie","2018 Jul","Ausina P, Da Silva D, Majerowicz D, Zancan P, Sola-Penna M"
> "P47857-1","27146165","Phosphofructokinase-1 Negatively Regulates Neurogenesis from Neural Stem Cells.","Neuroscience bulletin","2016 Jun","Zhang F, Qian X, Qin C, Lin Y, Wu H, Chang L, Luo C, Zhu D"
2946,2948c3211,3214
< "O88559-1","30315824","Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.","Experimental hematology","2019 Jan","Chen Y, Jones KL, Anastassiadis K, Kranz A, Stewart AF, Grembecka J, Meyerson M, Ernst P"
< "O88559-1","30099020","Mechanism of MEN1 gene in radiation-induced pulmonary fibrosis in mice.","Gene","2018 Dec 15","Wei W, Zhang HY, Gong XK, Dong Z, Chen ZY, Wang R, Yi JX, Shen YN, Jin SZ"
< "O88559-1","30120246","The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation.","Nature communications","2018 Aug 17","Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, Takemori A, Matsuda S, Kanoh M, Imai Y, Yasukawa M, Yamashita M"
---
> "Q9ET54-1","28739877","PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 1","Sun HM, Chen XL, Chen XJ, Liu J, Ma L, Wu HY, Huang QH, Xi XD, Yin T, Zhu J, Chen Z, Chen SJ"
> "Q9ET54-1","28340616","Lacking of palladin leads to multiple cellular events changes which contribute to NTD.","Neural development","2017 Mar 24","Tan J, Chen XJ, Shen CL, Zhang HX, Tang LY, Lu SY, Wu WT, Kuang Y, Fei J, Wang ZG"
> "Q9ET54-1","27865965","Palladin is involved in platelet activation and arterial thrombosis.","Thrombosis research","2017 Jan","Chen X, Fan X, Tan J, Shi P, Wang X, Wang J, Kuang Y, Fei J, Liu J, Dang S, Wang Z"
> "Q9ET54-1","14983521","Palladin is a novel binding partner for Ena/VASP family members.","Cell motility and the cytoskeleton","2004 May","Boukhelifa M, Parast MM, Bear JE, Gertler FB, Otey CA"
2955,2964c3221
< "Q6NZQ8-1","30356278","The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner.","PloS one","2018","Bhagwandin C, Ashbeck EL, Whalen M, Bandola-Simon J, Roche PA, Szajman A, Truong SM, Wertheim BC, Klimentidis YC, Ishido S, Renquist BJ, Lybarger L"
< "Q6NZQ8-1","30154416","March1-dependent modulation of donor MHC II on CD103(+) dendritic cells mitigates alloimmunity.","Nature communications","2018 Aug 28","Borges TJ, Murakami N, Machado FD, Murshid A, Lang BJ, Lopes RL, Bellan LM, Uehara M, Antunes KH, Perez-Saez MJ, Birrane G, Vianna P, Goncalves JIB, Zanin RF, Azzi J, Abdi R, Ishido S, Shin JS, Souza APD, Calderwood SK, Riella LV, Bonorino C"
< "Q6NZQ8-1","30001419","MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway.","PloS one","2018","Wilson KR, Liu H, Healey G, Vuong V, Ishido S, Herold MJ, Villadangos JA, Mintern JD"
< "Q6NZQ8-1","29854835","March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation.","Journal of immunology research","2018","Kishta OA, Sabourin A, Simon L, McGovern T, Raymond M, Galbas T, Majdoubi A, Ishido S, Martin JG, Thibodeau J"
< "Q6NZQ8-1","29378848","A major isoform of the E3 ubiquitin ligase March-I in antigen-presenting cells has regulatory sequences within its gene.","The Journal of biological chemistry","2018 Mar 23","Kaul S, Mittal SK, Roche PA"
< "Q6NZQ8-1","21220452","CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.","The Journal of experimental medicine","2011 Jan 17","Tze LE, Horikawa K, Domaschenz H, Howard DR, Roots CM, Rigby RJ, Way DA, Ohmura-Hoshino M, Ishido S, Andoniou CE, Degli-Esposti MA, Goodnow CC"
< "Q6NZQ8-1","21059907","Ubiquitination regulates MHC class II-peptide complex retention and degradation in dendritic cells.","Proceedings of the National Academy of Sciences of the United States of America","2010 Nov 23","Walseng E, Furuta K, Bosch B, Weih KA, Matsuki Y, Bakke O, Ishido S, Roche PA"
< "Q6NZQ8-1","19917682","Cutting edge: requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells.","Journal of immunology (Baltimore, Md. : 1950)","2009 Dec 1","Ohmura-Hoshino M, Matsuki Y, Mito-Yoshida M, Goto E, Aoki-Kawasumi M, Nakayama M, Ohara O, Ishido S"
< "Q6NZQ8-1","19880452","Discrete domains of MARCH1 mediate its localization, functional interactions, and posttranscriptional control of expression.","Journal of immunology (Baltimore, Md. : 1950)","2009 Nov 15","Jabbour M, Campbell EM, Fares H, Lybarger L"
< "Q6NZQ8-1","17255932","Novel regulation of MHC class II function in B cells.","The EMBO journal","2007 Feb 7","Matsuki Y, Ohmura-Hoshino M, Goto E, Aoki M, Mito-Yoshida M, Uematsu M, Hasegawa T, Koseki H, Ohara O, Nakayama M, Toyooka K, Matsuoka K, Hotta H, Yamamoto A, Ishido S"
---
> "Q8BHY3-1","18724360","TMEM16A confers receptor-activated calcium-dependent chloride conductance.","Nature","2008 Oct 30","Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U"
2976,2977d3232
< "Q9WV02-1","19403048","SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.","BMB reports","2009 Apr 30","Omura Y, Nishio Y, Takemoto T, Ikeuchi C, Sekine O, Morino K, Maeno Y, Obata T, Ugi S, Maegawa H, Kimura H, Kashiwagi A"
< "Q9WV02-1","17188681","RBMX is a novel hepatic transcriptional regulator of SREBP-1c gene response to high-fructose diet.","FEBS letters","2007 Jan 23","Takemoto T, Nishio Y, Sekine O, Ikeuchi C, Nagai Y, Maeno Y, Maegawa H, Kimura H, Kashiwagi A"
2982,2986c3237
< "Q3U1T9-1","26774822","Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease.","Cell","2016 Jan 14","Yang CW, Hojer CD, Zhou M, Wu X, Wuster A, Lee WP, Yaspan BL, Chan AC"
< "Q4FZC9-1","23761073","Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis.","Molecular biology of the cell","2013 Aug","Ketema M, Kreft M, Secades P, Janssen H, Sonnenberg A"
< "Q4FZC9-1","23336069","The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction.","Scientific reports","2013","Chambliss AB, Khatau SB, Erdenberger N, Robinson DK, Hodzic D, Longmore GD, Wirtz D"
< "Q4FZC9-1","17881500","Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin.","Journal of cell science","2007 Oct 1","Ketema M, Wilhelmsen K, Kuikman I, Janssen H, Hodzic D, Sonnenberg A"
< "Q4FZC9-1","16330710","Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.","The Journal of cell biology","2005 Dec 5","Wilhelmsen K, Litjens SH, Kuikman I, Tshimbalanga N, Janssen H, van den Bout I, Raymond K, Sonnenberg A"
---
> "Q05BC3-1","24859200","Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.","Nature neuroscience","2014 Jul","Kielar M, Tuy FP, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, Oegema R, Mancini GM, Bahi-Buisson N, Olaso R, Le Moing AG, Boutourlinsky K, Boucher D, Carpentier W, Berquin P, Deleuze JF, Belvindrah R, Borrell V, Welker E, Chelly J, Croquelois A, Francis F"
2992a3244,3247
> "Q8K2Z4-1","25474630","Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.","PLoS genetics","2014 Dec","Nishide K, Hirano T"
> "Q5XJV7-1","30655503","Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.","Translational psychiatry","2019 Jan 17","Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR"
> "Q5XJV7-1","30455454","Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition.","Nature neuroscience","2018 Dec","Deliu E, Arecco N, Morandell J, Dotter CP, Contreras X, Girardot C, Kasper EL, Kozlova A, Kishi K, Chiaradia I, Noh KM, Novarino G"
> "Q5XJV7-1","29180574","miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons.","Development (Cambridge, England)","2018 Jan 8","Villain G, Poissonnier L, Noueihed B, Bonfils G, Rivera JC, Chemtob S, Soncin F, Mattot V"
2993a3249
> "Q8CC21-1","28673544","TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.","Molecular cell","2017 Jul 6","Bottani E, Cerutti R, Harbour ME, Ravaglia S, Dogan SA, Giordano C, Fearnley IM, D'Amati G, Viscomi C, Fernandez-Vizarra E, Zeviani M"
2995c3251
< "F2Z472-1","15582586","Functional preservation of duplicated pair for RSVS III gene in the REST locus of rat 3q42.","Biochemical and biophysical research communications","2005 Jan 14","Lin HJ, Lee CM, Luo CW, Chen YH"
---
> "Q91YP6-1","22177965","The C-terminal polyproline-containing region of ELMO contributes to an increase in the life-time of the ELMO-DOCK complex.","Biochimie","2012 Mar","Sevajol M, Reiser JB, Chouquet A, Perard J, Ayala I, Gans P, Kleman JP, Housset D"
2996a3253,3254
> "Q64516-3","19546021","Weighted gene co-expression network analysis identifies biomarkers in glycerol kinase deficient mice.","Molecular genetics and metabolism","2009 Sep-Oct","MacLennan NK, Dong J, Aten JE, Horvath S, Rahib L, Ornelas L, Dipple KM, McCabe ER"
> "Q9EQH7-1","29688404","Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation.","Endocrinology","2018 Jun 1","Yin Y, Wang A, Feng L, Wang Y, Zhang H, Zhang I, Bany BM, Ma L"
2999a3258
> "Q8QZY4-1","25542898","Retbindin is an extracellular riboflavin-binding protein found at the photoreceptor/retinal pigment epithelium interface.","The Journal of biological chemistry","2015 Feb 20","Kelley RA, Al-Ubaidi MR, Naash MI"
3001,3006d3259
< "Q60668-1","30418981","Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each.","PloS one","2018","Dogar AM, Pauchard-Batschulat R, Grisoni-Neupert B, Richman L, Paillusson A, Pradervand S, Hagenbuchle O, Ambrosini G, Schmid CD, Bucher P, Kuhn LC"
< "Q60668-1","27784781","Autotaxin Expression Is Regulated at the Post-transcriptional Level by the RNA-binding Proteins HuR and AUF1.","The Journal of biological chemistry","2016 Dec 9","Sun S, Zhang X, Lyu L, Li X, Yao S, Zhang J"
< "Q60668-1","27452471","Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity.","Cell reports","2016 Aug 2","Chenette DM, Cadwallader AB, Antwine TL, Larkin LC, Wang J, Olwin BB, Schneider RJ"
< "Q60668-1","24891619","RNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels.","Molecular and cellular biology","2014 Aug","Panda AC, Abdelmohsen K, Yoon JH, Martindale JL, Yang X, Curtis J, Mercken EM, Chenette DM, Zhang Y, Schneider RJ, Becker KG, de Cabo R, Gorospe M"
< "Q60668-1","14715706","Interaction between 3' untranslated region of calcitonin receptor messenger ribonucleic acid (RNA) and adenylate/uridylate (AU)-rich element binding proteins (AU-rich RNA-binding factor 1 and Hu antigen R).","Endocrinology","2004 Apr","Yasuda S, Wada S, Arao Y, Kogawa M, Kayama F, Katayama S"
< "Q60668-1","12107167","Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1.","The Journal of biological chemistry","2002 Sep 20","Pioli PA, Hamilton BJ, Connolly JE, Brewer G, Rigby WF"
3023,3024c3276
< "Q99PV8-1","12717433","Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.","Nature immunology","2003 Jun","Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, Mishima Y, Hitomi J, Yamamoto T, Utsuyama M, Niwa O, Aizawa S, Kominami R"
< "Q99PV8-1","12565905","Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas.","Biochemical and biophysical research communications","2003 Feb 7","Wakabayashi Y, Inoue J, Takahashi Y, Matsuki A, Kosugi-Okano H, Shinbo T, Mishima Y, Niwa O, Kominami R"
---
> "Q9CPT0-1","23059823","Bcl-2 family member Bcl-G is not a proapoptotic protein.","Cell death &amp; disease","2012 Oct 11","Giam M, Okamoto T, Mintern JD, Strasser A, Bouillet P"
3035,3046c3287,3288
< "Q8R1G1-1","30573454","Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia.","Genes &amp; development","2019 Jan 1","Zhao Z, Wang L, Volk AG, Birch NW, Stoltz KL, Bartom ET, Marshall SA, Rendleman EJ, Nestler CM, Shilati J, Schiltz GE, Crispino JD, Shilatifard A"
< "Q8R1G1-1","25664857","Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.","The Journal of clinical investigation","2015 Mar 2","Takeda S, Sasagawa S, Oyama T, Searleman AC, Westergard TD, Cheng EH, Hsieh JJ"
< "Q8R1G1-1","25267403","Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.","Cell research","2014 Nov","Dong Y, Van Tine BA, Oyama T, Wang PI, Cheng EH, Hsieh JJ"
< "Q8R1G1-1","24176642","Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.","Developmental cell","2013 Oct 28","Oyama T, Sasagawa S, Takeda S, Hess RA, Lieberman PM, Cheng EH, Hsieh JJ"
< "Q8R1G1-1","18395097","EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.","Gastroenterology","2008 Apr","Niehof M, Borlak J"
< "Q8R1G1-1","16951254","Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.","Genes &amp; development","2006 Sep 1","Takeda S, Chen DY, Westergard TD, Fisher JK, Rubens JA, Sasagawa S, Kan JT, Korsmeyer SJ, Cheng EH, Hsieh JJ"
< "Q8BGB7-1","24236849","Analysis of quantitative trait loci in mice suggests a role of Enoph1 in stress reactivity.","Journal of neurochemistry","2014 Mar","Barth A, Bilkei-Gorzo A, Drews E, Otte DM, Diaz-Lacava A, Varadarajulu J, Turck CW, Wienker TF, Zimmer A"
< "Q8BGB7-1","19139748","Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways.","Molecular psychiatry","2010 Jul","Ditzen C, Varadarajulu J, Czibere L, Gonik M, Targosz BS, Hambsch B, Bettecken T, Kessler MS, Frank E, Bunck M, Teplytska L, Erhardt A, Holsboer F, Muller-Myhsok B, Landgraf R, Turck CW"
< "Q9ES97-1","28238655","RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.","Current biology : CB","2017 Mar 6","Bastide A, Peretti D, Knight JR, Grosso S, Spriggs RV, Pichon X, Sbarrato T, Roobol A, Roobol J, Vito D, Bushell M, von der Haar T, Smales CM, Mallucci GR, Willis AE"
< "Q9ES97-1","15946766","Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain.","Brain research. Molecular brain research","2005 Aug 18","Cai Y, Saiyin H, Lin Q, Zhang P, Tang L, Pan X, Yu L"
< "Q9ES97-1","15350194","Tissue specificity and regulation of the N-terminal diversity of reticulon 3.","The Biochemical journal","2005 Jan 1","Di Scala F, Dupuis L, Gaiddon C, De Tapia M, Jokic N, Gonzalez de Aguilar JL, Raul JS, Ludes B, Loeffler JP"
< "Q9ES97-1","11990451","Molecular cloning and characterization of the mouse reticulon 3 cDNA.","Cellular and molecular biology (Noisy-le-Grand, France)","2002 Mar","Hamada N, Iwahashi J, Suzuki K, Ogi H, Kashiwagi T, Hara K, Toyoda M, Yamada T, Toyoda T"
---
> "Q80VJ2-1","15327771","Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator.","Molecular cell","2004 Aug 27","Zhao X, Patton JR, Davis SL, Florence B, Ames SJ, Spanjaard RA"
> "Q8BSN3-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
3048a3291,3292
> "Q8R035-1","27029019","Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria.","PLoS genetics","2016 Mar","Feaga HA, Quickel MD, Hankey-Giblin PA, Keiler KC"
> "Q8R035-1","20869366","Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality.","Journal of molecular biology","2010 Nov 26","Handa Y, Hikawa Y, Tochio N, Kogure H, Inoue M, Koshiba S, Guntert P, Inoue Y, Kigawa T, Yokoyama S, Nameki N"
3053a3298,3300
> "Q91V88-1","28842827","Nephronectin is Decreased in Metastatic Breast Carcinoma and Related to Metastatic Organs.","Pathology oncology research : POR","2018 Jul","Dilmac S, Erin N, Demir N, Tanriover G"
> "Q91V88-1","28345658","Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains.","Scientific reports","2017 Mar 27","Arai C, Yoshizaki K, Miyazaki K, Saito K, Yamada A, Han X, Funada K, Fukumoto E, Haruyama N, Iwamoto T, Takahashi I, Fukumoto S"
> "Q91V88-1","17537792","The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.","Development (Cambridge, England)","2007 Jul","Linton JM, Martin GR, Reichardt LF"
3062a3310
> "Q6P3A8-1","16875466","Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice.","The Biochemical journal","2006 Nov 15","Joshi MA, Jeoung NH, Obayashi M, Hattab EM, Brocken EG, Liechty EA, Kubek MJ, Vattem KM, Wek RC, Harris RA"
3066a3315
> "Q8R139-1","16873718","Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.","Circulation research","2006 Sep 1","Barnes K, Dobrzynski H, Foppolo S, Beal PR, Ismat F, Scullion ER, Sun L, Tellez J, Ritzel MW, Claycomb WC, Cass CE, Young JD, Billeter-Clark R, Boyett MR, Baldwin SA"
3076,3077c3325,3326
< "Q9JLV2-1","29704259","TRUSS Exacerbates NAFLD Development by Promoting IkappaBalpha Degradation in Mice.","Hepatology (Baltimore, Md.)","2018 Nov","Yu CJ, Wang QS, Wu MM, Song BL, Liang C, Lou J, Tang LL, Yu XD, Niu N, Yang X, Zhang BL, Qu Y, Liu Y, Dong ZC, Zhang ZR"
< "Q9JLV2-1","14585990","TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB.","Molecular and cellular biology","2003 Nov","Soond SM, Terry JL, Colbert JD, Riches DW"
---
> "Q07076-1","28176245","Effect of annexin A7 suppression on the apoptosis of gastric cancer cells.","Molecular and cellular biochemistry","2017 May","Ye W, Li Y, Fan L, Zhao Q, Yuan H, Tan B, Zhang Z"
> "Q8R2G6-1","15325258","URB expression in human bone marrow stromal cells and during mouse development.","Biochemical and biophysical research communications","2004 Sep 17","Liu Y, Monticone M, Tonachini L, Mastrogiacomo M, Marigo V, Cancedda R, Castagnola P"
3078a3328,3330
> "P39688-1","29353218","Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ss/Fyn pathway.","Redox biology","2018 May","Xin Y, Bai Y, Jiang X, Zhou S, Wang Y, Wintergerst KA, Cui T, Ji H, Tan Y, Cai L"
> "P39688-1","29180007","Tyrosine kinase Fyn regulates iNOS expression in LPS-stimulated astrocytes via modulation of ERK phosphorylation.","Biochemical and biophysical research communications","2018 Jan 1","Ko HM, Lee SH, Bang M, Kim KC, Jeon SJ, Park YM, Han SH, Kim HY, Lee J, Shin CY"
> "Q8R1P5-1","18209473","Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2008","Theilig F, Goranova I, Hirsch JR, Wieske M, Unsal S, Bachmann S, Veh RW, Derst C"
3081,3082d3332
< "P27512-1","30096208","Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction.","PloS one","2018","Aarts SABM, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E"
< "P27512-1","29452567","A critical role for both CD40 and VLA5 in angiotensin II-mediated thrombosis and inflammation.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Jun","Senchenkova EY, Russell J, Vital SA, Yildirim A, Orr AW, Granger DN, Gavins FNE"
3084,3086c3334,3337
< "C0LLJ0-1","28189564","H7N9 Influenza A Virus Exhibits Importin-alpha7-Mediated Replication in the Mammalian Respiratory Tract.","The American journal of pathology","2017 Apr","Bertram S, Thiele S, Dreier C, Resa-Infante P, Preuss A, van Riel D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD, Gabriel G"
< "C0LLJ0-1","20699224","Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.","The Journal of biological chemistry","2010 Oct 22","Hu J, Wang F, Yuan Y, Zhu X, Wang Y, Zhang Y, Kou Z, Wang S, Gao S"
< "C0LLJ0-1","20701745","Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.","BMC cell biology","2010 Aug 11","Kelley JB, Talley AM, Spencer A, Gioeli D, Paschal BM"
---
> "Q8CI59-1","12606722","The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.","Proceedings of the National Academy of Sciences of the United States of America","2003 Mar 4","Passer BJ, Nancy-Portebois V, Amzallag N, Prieur S, Cans C, Roborel de Climens A, Fiucci G, Bouvard V, Tuynder M, Susini L, Morchoisne S, Crible V, Lespagnol A, Dausset J, Oren M, Amson R, Telerman A"
> "Q7TQA1-1","28686733","The short mRNA isoform of the immunoglobulin superfamily, member 1 gene encodes an intracellular glycoprotein.","PloS one","2017","Wang Y, Brule E, Silander T, Bak B, Joustra SD, Bernard DJ"
> "Q7TQA1-1","28324000","TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice.","Endocrinology","2017 Apr 1","Turgeon MO, Silander TL, Doycheva D, Liao XH, Rigden M, Ongaro L, Zhou X, Joustra SD, Wit JM, Wade MG, Heuer H, Refetoff S, Bernard DJ"
> "Q00417-1","30420627","TCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of CD4(+)CD8(+) thymocytes.","Nature immunology","2018 Dec","Emmanuel AO, Arnovitz S, Haghi L, Mathur PS, Mondal S, Quandt J, Okoreeh MK, Maienschein-Cline M, Khazaie K, Dose M, Gounari F"
3087a3339,3341
> "Q8K209-1","29855662","The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve beta-cell function.","Cellular and molecular life sciences : CMLS","2018 Nov","Olaniru OE, Pingitore A, Giera S, Piao X, Castanera Gonzalez R, Jones PM, Persaud SJ"
> "Q8K209-1","29367382","GPR56/ADGRG1 regulates development and maintenance of peripheral myelin.","The Journal of experimental medicine","2018 Mar 5","Ackerman SD, Luo R, Poitelon Y, Mogha A, Harty BL, D'Rozario M, Sanchez NE, Lakkaraju AKK, Gamble P, Li J, Qu J, MacEwan MR, Ray WZ, Aguzzi A, Feltri ML, Piao X, Monk KR"
> "Q8K209-1","15044805","G protein-coupled receptor-dependent development of human frontal cortex.","Science (New York, N.Y.)","2004 Mar 26","Piao X, Hill RS, Bodell A, Chang BS, Basel-Vanagaite L, Straussberg R, Dobyns WB, Qasrawi B, Winter RM, Innes AM, Voit T, Ross ME, Michaud JL, Descarie JC, Barkovich AJ, Walsh CA"
3090a3345
> "Q01887-1","29180410","Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.","Proceedings of the National Academy of Sciences of the United States of America","2017 Dec 12","Chang WH, Choi SH, Moon BS, Cai M, Lyu J, Bai J, Gao F, Hajjali I, Zhao Z, Campbell DB, Weiner LP, Lu W"
3091a3347,3351
> "P42337-1","30905780","Up regulation of isoleucyl-tRNA synthetase promotes vascular smooth muscle cells dysfunction via p38 MAPK/PI3K signaling pathways.","Life sciences","2019 May 1","Li B, Wang Z, Chen R, Hong J, Wu Q, Hu J, Hu Z, Zhang M"
> "Q9JMH6-1","30805084","Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia.","Oxidative medicine and cellular longevity","2019","Wall SB, Wood R, Dunigan K, Li Q, Li R, Rogers LK, Tipple TE"
> "Q9JMH6-1","29749372","The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation.","Nature communications","2018 May 10","Muri J, Heer S, Matsushita M, Pohlmeier L, Tortola L, Fuhrer T, Conrad M, Zamboni N, Kisielow J, Kopf M"
> "Q9JMH6-1","28775321","MiR-23-TrxR1 as a novel molecular axis in skeletal muscle differentiation.","Scientific reports","2017 Aug 3","Mercatelli N, Fittipaldi S, De Paola E, Dimauro I, Paronetto MP, Jackson MJ, Caporossi D"
> "Q9JMH6-1","28686716","GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.","PloS one","2017","Han C, Kim MJ, Ding D, Park HJ, White K, Walker L, Gu T, Tanokura M, Yamasoba T, Linser P, Salvi R, Someya S"
3098,3100c3358,3360
< "P49446-1","25381250","Adaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase in osteoclasts.","The Journal of biological chemistry","2014 Dec 26","Levy-Apter E, Finkelshtein E, Vemulapalli V, Li SS, Bedford MT, Elson A"
< "P49446-1","24694598","Protein tyrosine phosphatases epsilon and alpha perform nonredundant roles in osteoclasts.","Molecular biology of the cell","2014 Jun","Finkelshtein E, Lotinun S, Levy-Apter E, Arman E, den Hertog J, Baron R, Elson A"
< "P49446-1","22722941","Multifaceted modulation of K+ channels by protein-tyrosine phosphatase epsilon tunes neuronal excitability.","The Journal of biological chemistry","2012 Aug 10","Ebner-Bennatan S, Patrich E, Peretz A, Kornilov P, Tiran Z, Elson A, Attali B"
---
> "Q8BG05-1","22546510","Expression profile and interactions of hnRNP A3 within hnRNP/mRNP complexes in mammals.","Archives of biochemistry and biophysics","2012 Jul 15","Papadopoulou C, Boukakis G, Ganou V, Patrinou-Georgoula M, Guialis A"
> "Q8BG05-1","20885981","Heterogeneous nuclear ribonucleoprotein A3 is the liver nuclear protein binding to age related increase element RNA of the factor IX gene.","PloS one","2010 Sep 24","Hamada T, Kurachi S, Kurachi K"
> "Q3KNY5-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
3104,3109d3363
< "Q9Z148-1","30455462","Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours.","Nature cell biology","2018 Dec","Avgustinova A, Symeonidi A, Castellanos A, Urdiroz-Urricelqui U, Sole-Boldo L, Martin M, Perez-Rodriguez I, Prats N, Lehner B, Supek F, Benitah SA"
< "Q9Z148-1","29720423","Cutting Edge: The Histone Methyltransferase G9a Is Required for Silencing of Helper T Lineage-Associated Genes in Proliferating CD8 T Cells.","Journal of immunology (Baltimore, Md. : 1950)","2018 Jun 15","Verbaro DJ, Sakurai N, Kim B, Shinkai Y, Egawa T"
< "Q9Z148-1","29745895","G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst.","eLife","2018 May 10","Zylicz JJ, Borensztein M, Wong FC, Huang Y, Lee C, Dietmann S, Surani MA"
< "Q9Z148-1","29774081","G9a stimulates CRC growth by inducing p53 Lys373 dimethylation-dependent activation of Plk1.","Theranostics","2018","Zhang J, Wang Y, Shen Y, He P, Ding J, Chen Y"
< "Q9Z148-1","12586828","Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center.","The Journal of biological chemistry","2003 Apr 25","Xin Z, Tachibana M, Guggiari M, Heard E, Shinkai Y, Wagstaff J"
< "Q9Z148-1","12130538","G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.","Genes &amp; development","2002 Jul 15","Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y"
3112,3114c3366
< "Q3UDK1-1","25992615","TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption.","PloS one","2015","Witwicka H, Jia H, Kutikov A, Reyes-Gutierrez P, Li X, Odgren PR"
< "Q3UDK1-1","18849341","FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.","The Journal of biological chemistry","2008 Dec 5","Sanada T, Takaesu G, Mashima R, Yoshida R, Kobayashi T, Yoshimura A"
< "Q3UDK1-1","16221674","FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.","The Journal of biological chemistry","2005 Dec 16","Mashima R, Saeki K, Aki D, Minoda Y, Takaki H, Sanada T, Kobayashi T, Aburatani H, Yamanashi Y, Yoshimura A"
---
> "Q8BLQ9-1","29217450","Cadm2 regulates body weight and energy homeostasis in mice.","Molecular metabolism","2018 Feb","Yan X, Wang Z, Schmidt V, Gauert A, Willnow TE, Heinig M, Poy MN"
3119a3372,3375
> "Q8BPU7-1","30643265","A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis.","Nature immunology","2019 Feb","Arandjelovic S, Perry JSA, Lucas CD, Penberthy KK, Kim TH, Zhou M, Rosen DA, Chuang TY, Bettina AM, Shankman LS, Cohen AH, Gaultier A, Conrads TP, Kim M, Elliott MR, Ravichandran KS"
> "Q8BPU7-1","30219846","Engulfment and Cell Motility Protein 1 Protects Against DSS-induced Colonic Injury in Mice via Rac1 Activation.","Journal of Crohn's &amp; colitis","2019 Jan 1","Zheng XB, Liu HS, Zhang LJ, Liu XH, Zhong XL, Zhou C, Hu T, Wu XR, Hu JC, Lian L, Deng QL, Chen YF, Ke J, He XW, Wu XJ, He XS, Lan P"
> "Q8BPU7-1","29029244","ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection.","The Journal of infectious diseases","2017 Dec 19","Sarkar A, Tindle C, Pranadinata RF, Reed S, Eckmann L, Stappenbeck TS, Ernst PB, Das S"
> "Q8BPU7-1","28219480","De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFbeta-deficient squamous cell carcinoma from transition zones.","eLife","2017 Feb 21","McCauley HA, Chevrier V, Birnbaum D, Guasch G"
3120a3377,3378
> "P97300-2","29056295","Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca(2+)-ATPases and Key Regulators of Ca(2+) Clearance.","Neuron","2017 Nov 15","Schmidt N, Kollewe A, Constantin CE, Henrich S, Ritzau-Jost A, Bildl W, Saalbach A, Hallermann S, Kulik A, Fakler B, Schulte U"
> "P97300-2","28779130","Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration.","Scientific reports","2017 Aug 4","Herrera-Molina R, Mlinac-Jerkovic K, Ilic K, Stober F, Vemula SK, Sandoval M, Milosevic NJ, Simic G, Smalla KH, Goldschmidt J, Bognar SK, Montag D"
3129a3388
> "A1Y9I9-1","18794526","A catechol-O-methyltransferase that is essential for auditory function in mice and humans.","Proceedings of the National Academy of Sciences of the United States of America","2008 Sep 23","Du X, Schwander M, Moresco EM, Viviani P, Haller C, Hildebrand MS, Pak K, Tarantino L, Roberts A, Richardson H, Koob G, Najmabadi H, Ryan AF, Smith RJ, Muller U, Beutler B"
3131,3132c3390,3393
< "Q8CBY1-1","24799716","Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.","Proceedings of the National Academy of Sciences of the United States of America","2014 May 20","Chen Z, Holland W, Shelton JM, Ali A, Zhan X, Won S, Tomisato W, Liu C, Li X, Moresco EM, Beutler B"
< "Q8CBY1-1","16221671","Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.","The Journal of biological chemistry","2005 Dec 30","Baez MV, Boccaccio GL"
---
> "Q71M36-1","24265546","Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/ chondroitin sulfate proteoglycan 5.","Molecular vision","2013","Cottet S, Juttner R, Voirol N, Chambon P, Rathjen FG, Schorderet DF, Escher P"
> "Q71M36-1","23889129","Impaired presynaptic function and elimination of synapses at premature stages during postnatal development of the cerebellum in the absence of CALEB (CSPG5/neuroglycan C).","The European journal of neuroscience","2013 Nov","Juttner R, Montag D, Craveiro RB, Babich A, Vetter P, Rathjen FG"
> "Q71M36-1","11929867","Phosphorylation of neuroglycan C, a brain-specific transmembrane chondroitin sulfate proteoglycan, and its localization in the lipid rafts.","The Journal of biological chemistry","2002 Jun 7","Yamauchi S, Tokita Y, Aono S, Matsui F, Shuo T, Ito H, Kato K, Kasahara K, Oohira A"
> "P35582-1","30475207","FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.","eLife","2018 Nov 26","Camolotto SA, Pattabiraman S, Mosbruger TL, Jones A, Belova VK, Orstad G, Streiff M, Salmond L, Stubben C, Kaestner KH, Snyder EL"
3138,3140d3398
< "Q7TNK1-1","29298325","Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype.","PloS one","2018","Xu P, Morrison JP, Foley JF, Stumpo DJ, Ward T, Zeldin DC, Blackshear PJ"
< "Q7TNK1-1","14701801","Restricted expression and photic induction of a novel mouse regulatory factor X4 transcript in the suprachiasmatic nucleus.","The Journal of biological chemistry","2004 Mar 12","Araki R, Takahashi H, Fukumura R, Sun F, Umeda N, Sujino M, Inouye ST, Saito T, Abe M"
< "Q7TNK1-1","12925582","Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4.","Development (Cambridge, England)","2003 Oct","Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL, Zeldin DC"
3144,3155c3402,3407
< "Q80YV2-1","22955283","Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M.","The Journal of biological chemistry","2012 Nov 2","Illert AL, Zech M, Moll C, Albers C, Kreutmair S, Peschel C, Bassermann F, Duyster J"
< "Q80YV2-1","22696294","Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase.","Development (Cambridge, England)","2012 Jul","Illert AL, Kawaguchi H, Antinozzi C, Bassermann F, Quintanilla-Martinez L, von Klitzing C, Hiwatari M, Peschel C, de Rooij DG, Morris SW, Barchi M, Duyster J"
< "Q80YV2-1","22205987","APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1.","PloS one","2011","Klitzing Cv, Huss R, Illert AL, Froschl A, Wotzel S, Peschel C, Bassermann F, Duyster J"
< "Q80YV2-1","12748172","Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).","The Journal of biological chemistry","2003 Aug 8","Ouyang T, Bai RY, Bassermann F, von Klitzing C, Klumpen S, Miething C, Morris SW, Peschel C, Duyster J"
< "P58283-1","27995769","TRIAD3/RNF216 mutations associated with Gordon Holmes syndrome lead to synaptic and cognitive impairments via Arc misregulation.","Aging cell","2017 Apr","Husain N, Yuan Q, Yen YC, Pletnikova O, Sally DQ, Worley P, Bichler Z, Shawn Je H"
< "P58283-1","28154178","Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216.","The Journal of biological chemistry","2017 Mar 10","Kumazoe M, Nakamura Y, Yamashita M, Suzuki T, Takamatsu K, Huang Y, Bae J, Yamashita S, Murata M, Yamada S, Shinoda Y, Yamaguchi W, Toyoda Y, Tachibana H"
< "P58283-1","25484083","Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination.","Autophagy","2014","Xu C, Feng K, Zhao X, Huang S, Cheng Y, Qian L, Wang Y, Sun H, Jin M, Chuang TH, Zhang Y"
< "Q7TMK9-1","28436985","Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.","Nature genetics","2017 Jun","Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, Kwon JA, Meydan C, Perales-Paton J, Arshi A, Gonen M, Famulare C, Patel M, Paietta E, Tallman MS, Lu Y, Glass J, Garret-Bakelman FE, Melnick A, Levine R, Al-Shahrour F, Jaras M, Hacohen N, Hwang A, Garippa R, Lengner CJ, Armstrong SA, Cerchietti L, Cowley GS, Root D, Doench J, Leslie C, Ebert BL, Kharas MG"
< "Q7TMK9-1","27732855","The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting.","Cell reports","2016 Oct 11","Santangelo L, Giurato G, Cicchini C, Montaldo C, Mancone C, Tarallo R, Battistelli C, Alonzi T, Weisz A, Tripodi M"
< "Q7TMK9-1","27392095","HnRNP Q Has a Suppressive Role in the Translation of Mouse Cryptochrome1.","PloS one","2016","Lim I, Jung Y, Kim DY, Kim KT"
< "Q7TMK9-1","26658614","hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation.","Molecular biology of the cell","2016 Feb 1","Williams KR, McAninch DS, Stefanovic S, Xing L, Allen M, Li W, Feng Y, Mihailescu MR, Bassell GJ"
< "Q7TMK9-1","11994298","Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding protein.","The Journal of biological chemistry","2002 Jul 12","Hresko RC, Mueckler M"
---
> "A2BED8-1","22075566","Identification of SAMT family proteins as substrates of MARCH11 in mouse spermatids.","Histochemistry and cell biology","2012 Jan","Yogo K, Tojima H, Ohno JY, Ogawa T, Nakamura N, Hirose S, Takeya T, Kohsaka T"
> "Q8BZN4-1","30446657","NUAK2 is a critical YAP target in liver cancer.","Nature communications","2018 Nov 16","Yuan WC, Pepe-Mooney B, Galli GG, Dill MT, Huang HT, Hao M, Wang Y, Liang H, Calogero RA, Camargo FD"
> "Q8BZN4-1","29298809","Sucrose Nonfermenting-Related Kinase Regulates Both Adipose Inflammation and Energy Homeostasis in Mice and Humans.","Diabetes","2018 Mar","Li J, Feng B, Nie Y, Jiao P, Lin X, Huang M, An R, He Q, Zhou HE, Salomon A, Sigrist KS, Wu Z, Liu S, Xu H"
> "Q8BZN4-1","26690705","The AMPK-related kinase SNARK regulates muscle mass and myocyte survival.","The Journal of clinical investigation","2016 Feb","Lessard SJ, Rivas DA, So K, Koh HJ, Queiroz AL, Hirshman MF, Fielding RA, Goodyear LJ"
> "Q8BZN4-1","20713714","Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle.","Proceedings of the National Academy of Sciences of the United States of America","2010 Aug 31","Koh HJ, Toyoda T, Fujii N, Jung MM, Rathod A, Middelbeek RJ, Lessard SJ, Treebak JT, Tsuchihara K, Esumi H, Richter EA, Wojtaszewski JF, Hirshman MF, Goodyear LJ"
> "Q8BZN4-1","18307533","Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci.","Cancer science","2008 Apr","Tsuchihara K, Ogura T, Fujioka R, Fujii S, Kuga W, Saito M, Ochiya T, Ochiai A, Esumi H"
3159a3412,3416
> "Q8C6P8-1","28476430","Imprinted control regions include composite DNA elements consisting of the ZFP57 binding site overlapping MLL1 morphemes.","Genomics","2017 Jul","Bina M"
> "Q8C6P8-1","27257070","ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells.","Nucleic acids research","2016 Sep 30","Riso V, Cammisa M, Kukreja H, Anvar Z, Verde G, Sparago A, Acurzio B, Lad S, Lonardo E, Sankar A, Helin K, Feil R, Fico A, Angelini C, Grimaldi G, Riccio A"
> "Q8C6P8-1","26481358","ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells.","Nucleic acids research","2016 Feb 18","Anvar Z, Cammisa M, Riso V, Baglivo I, Kukreja H, Sparago A, Girardot M, Lad S, De Feis I, Cerrato F, Angelini C, Feil R, Pedone PV, Grimaldi G, Riccio A"
> "Q8C6P8-1","26025256","Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.","Genome biology","2015 May 30","Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC"
> "Q8C6P8-1","18854139","A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.","Developmental cell","2008 Oct","Li X, Ito M, Zhou F, Youngson N, Zuo X, Leder P, Ferguson-Smith AC"
3168a3426,3427
> "Q6PKN7-1","25525809","Maintenance of leukemia-initiating cells is regulated by the CDK inhibitor Inca1.","PloS one","2014","Baumer N, Baumer S, Berkenfeld F, Stehling M, Kohler G, Berdel WE, Muller-Tidow C, Tschanter P"
> "Q6PKN7-1","21540187","Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.","The Journal of biological chemistry","2011 Aug 12","Baumer N, Tickenbrock L, Tschanter P, Lohmeyer L, Diederichs S, Baumer S, Skryabin BV, Zhang F, Agrawal-Singh S, Kohler G, Berdel WE, Serve H, Koschmieder S, Muller-Tidow C"
3186a3446
> "O55042-1","30503521","Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons.","American journal of human genetics","2018 Dec 6","McClymont SA, Hook PW, Soto AI, Reed X, Law WD, Kerans SJ, Waite EL, Briceno NJ, Thole JF, Heckman MG, Diehl NN, Wszolek ZK, Moore CD, Zhu H, Akiyama JA, Dickel DE, Visel A, Pennacchio LA, Ross OA, Beer MA, McCallion AS"
3189,3192d3448
< "Q9D7I0-1","18677103","Cell cycle regulation by the pro-apoptotic gene Scotin.","Cell cycle (Georgetown, Tex.)","2008 Aug","Gupta RK, Tripathi R, Naidu BJ, Srinivas UK, Shashidhara LS"
< "Q9D7I0-1","18164684","Scotin: A new p63 target gene expressed during epidermal differentiation.","Biochemical and biophysical research communications","2008 Mar 7","Zocchi L, Bourdon JC, Codispoti A, Knight R, Lane DP, Melino G, Terrinoni A"
< "Q9D7I0-1","17889823","The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane.","Archives of biochemistry and biophysics","2007 Nov 1","Draeby I, Woods YL, la Cour JM, Mollerup J, Bourdon JC, Berchtold MW"
< "Q9D7I0-1","12135983","Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane.","The Journal of cell biology","2002 Jul 22","Bourdon JC, Renzing J, Robertson PL, Fernandes KN, Lane DP"
3203c3459
< "P68404-1","29744369","Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice.","Journal of diabetes research","2018","Zheng J, Wang Y, Han S, Luo Y, Sun X, Zhu N, Zhao L, Li J"
---
> "Q7TNV9-1","20483750","Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.","Journal of immunology (Baltimore, Md. : 1950)","2010 Jun 15","Rohrl J, Yang D, Oppenheim JJ, Hehlgans T"
3207d3462
< "P97447-1","30260394","Cardiomyopathy and altered integrin-actin signaling in Fhl1 mutant female mice.","Human molecular genetics","2019 Jan 15","Kubota A, Juanola-Falgarona M, Emmanuele V, Sanchez-Quintero MJ, Kariya S, Sera F, Homma S, Tanji K, Quinzii CM, Hirano M"
3210,3213c3465,3474
< "Q9QYB8-1","29032200","Sez6l2 regulates phosphorylation of ADD and neuritogenesis.","Biochemical and biophysical research communications","2017 Dec 9","Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S"
< "Q9QYB8-1","27480796","Acute drug-induced spine changes in the nucleus accumbens are dependent on beta-adducin.","Neuropharmacology","2016 Nov","Engmann O, Giralt A, Girault JA"
< "Q9QYB8-1","15728854","Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2005 Feb 23","Rabenstein RL, Addy NA, Caldarone BJ, Asaka Y, Gruenbaum LM, Peters LL, Gilligan DM, Fitzsimonds RM, Picciotto MR"
< "P54830-1","29508281","Altered Intracellular Calcium Homeostasis Underlying Enhanced Glutamatergic Transmission in Striatal-Enriched Tyrosine Phosphatase (STEP) Knockout Mice.","Molecular neurobiology","2018 Oct","Bosco F, Valente P, Milanese M, Piccini A, Messa M, Bonanno G, Lombroso P, Baldelli P, Benfenati F, Giovedi S"
---
> "Q9R1Q6-1","29466738","Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b.","Cell reports","2018 Feb 20","Lowe M, Lage J, Paatela E, Munson D, Hostager R, Yuan C, Katoku-Kikyo N, Ruiz-Estevez M, Asakura Y, Staats J, Qahar M, Lohman M, Asakura A, Kikyo N"
> "Q9R1Q6-1","27009467","RORgammat+ cells selectively express redundant cation channels linked to the Golgi apparatus.","Scientific reports","2016 Mar 24","Drujont L, Lemoine A, Moreau A, Bienvenu G, Lancien M, Cens T, Guillot F, Beriou G, Bouchet-Delbos L, Fehling HJ, Chiffoleau E, Nicot AB, Charnet P, Martin JC, Josien R, Cuturi MC, Louvet C"
> "Q6DIC0-1","30522882","Brahma deficiency in keratinocytes promotes UV carcinogenesis by accelerating the escape from cell cycle arrest and the formation of DNA photolesions.","Journal of dermatological science","2018 Dec","Farrell AW, Halliday GM, Lyons JG"
> "Q61103-1","26571505","SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance.","PloS one","2015","Cruickshank VA, Sroczynska P, Sankar A, Miyagi S, Rundsten CF, Johansen JV, Helin K"
> "Q8BWG8-1","30144357","beta-Arrestin1 alleviates acute pancreatitis via repression of NF-kappaBp65 activation.","Journal of gastroenterology and hepatology","2019 Jan","Tao L, Lin X, Tan S, Lei Y, Liu H, Guo Y, Zheng F, Wu B"
> "Q8BWG8-1","30591079","beta-arrestin 1 regulates beta2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.","Skeletal muscle","2018 Dec 27","Kim J, Grotegut CA, Wisler JW, Li T, Mao L, Chen M, Chen W, Rosenberg PB, Rockman HA, Lefkowitz RJ"
> "Q99PN3-1","29203640","Transforming Growth Factor beta-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC.","Molecular and cellular biology","2018 Mar 1","Nakagawa T, Hosogane M, Nakagawa M, Morohoshi A, Funayama R, Nakayama K"
> "Q99PN3-1","25763818","TRIM26 negatively regulates interferon-beta production and antiviral response through polyubiquitination and degradation of nuclear IRF3.","PLoS pathogens","2015 Mar","Wang P, Zhao W, Zhao K, Zhang L, Gao C"
> "P40224-2","30898705","CXCL12 expression in aborted mouse uteri induced by IFN-gamma: Potential anti-inflammatory effect involves in endometrial restoration after abortion in mice.","Gene","2019 Jun 5","Chao HH, Li L, Gao X, Wang C, Yue W"
> "O55047-1","28708136","Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.","Cell death and differentiation","2017 Nov","Segura-Bayona S, Knobel PA, Gonzalez-Buron H, Youssef SA, Pena-Blanco A, Coyaud E, Lopez-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH"
3217a3479,3482
> "Q8BT07-1","29683733","Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Sep","Sinha D, Kalimutho M, Bowles J, Chan AL, Merriner DJ, Bain AL, Simmons JL, Freire R, Lopez JA, Hobbs RM, O'Bryan MK, Khanna KK"
> "Q8BT07-1","26582107","Cep55 regulates spindle organization and cell cycle progression in meiotic oocyte.","Scientific reports","2015 Nov 19","Xu ZY, Ma XS, Qi ST, Wang ZB, Guo L, Schatten H, Sun QY, Sun YP"
> "Q8BT07-1","20176808","TEX14 interacts with CEP55 to block cell abscission.","Molecular and cellular biology","2010 May","Iwamori T, Iwamori N, Ma L, Edson MA, Greenbaum MP, Matzuk MM"
> "Q8BT07-1","20186884","Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes.","Journal of cellular biochemistry","2010 Apr 15","Chang YC, Chen YJ, Wu CH, Wu YC, Yen TC, Ouyang P"
3226,3228c3491,3492
< "Q8VBV4-2","29633504","FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy.","Molecular oncology","2018 Jun","Xiao Y, Yin C, Wang Y, Lv H, Wang W, Huang Y, Perez-Losada J, Snijders AM, Mao JH, Zhang P"
< "Q8VBV4-2","29475832","Hepatic F-Box Protein FBXW7 Maintains Glucose Homeostasis Through Degradation of Fetuin-A.","Diabetes","2018 May","Zhao J, Xiong X, Li Y, Liu X, Wang T, Zhang H, Jiao Y, Jiang J, Zhang H, Tang Q, Gao X, Li X, Lu Y, Liu B, Hu C, Li X"
< "Q8VBV4-2","29550488","Genetic Deletion of Fbw7 in the mouse intestinal epithelium aggravated dextran sodium sulfate-induced colitis by modulating the inflammatory response of NF-kappaB pathway.","Biochemical and biophysical research communications","2018 Apr 15","Li H, Liang Y, Lai X, Wang W, Zhang J, Chen S"
---
> "Q9WVG6-1","30391528","Dorsal Root Ganglia Coactivator-associated Arginine Methyltransferase 1 Contributes to Peripheral Nerve Injury-induced Pain Hypersensitivities.","Neuroscience","2018 Dec 1","Mo K, Xu H, Gong H, Lei H, Wang Y, Guo W, Xu S, Tu W"
> "Q9WVG6-1","30366907","A C9orf72-CARM1 axis regulates lipid metabolism under glucose starvation-induced nutrient stress.","Genes &amp; development","2018 Nov 1","Liu Y, Wang T, Ji YJ, Johnson K, Liu H, Johnson K, Bailey S, Suk Y, Lu YN, Liu M, Wang J"
3229a3494
> "Q91XU3-1","18753295","Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron.","American journal of physiology. Renal physiology","2008 Nov","Clarke JH, Emson PC, Irvine RF"
3231d3495
< "Q810F8-1","20162674","A unique expression pattern of Tbx10 in the hindbrain as revealed by Tbx10(LacZ) allele.","Genesis (New York, N.Y. : 2000)","2010 May","Xue XD, Kimura W, Wang B, Hikosaka K, Itakura T, Uezato T, Matsuda M, Koseki H, Miura N"
3235a3500,3503
> "Q9Z0Z4-1","30060949","Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.","Biochemical and biophysical research communications","2018 Sep 10","Xu E, Chen M, Zheng J, Maimaitiming Z, Zhong T, Chen H"
> "Q9Z0Z4-1","29883959","Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.","Redox biology","2018 Jul","Chen M, Zheng J, Liu G, Xu E, Wang J, Fuqua BK, Vulpe CD, Anderson GJ, Chen H"
> "Q9Z0Z4-1","30182051","Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin.","Cellular and molecular gastroenterology and hepatology","2018","Fuqua BK, Lu Y, Frazer DM, Darshan D, Wilkins SJ, Dunn L, Loguinov AV, Kogan SC, Matak P, Chen H, Dunaief JL, Vulpe CD, Anderson GJ"
> "Q9Z0Z4-1","29355933","Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.","FEBS letters","2018 Feb","Zheng J, Chen M, Liu G, Xu E, Chen H"
3238a3507
> "Q8QZY2-1","19372376","Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.","Proceedings of the National Academy of Sciences of the United States of America","2009 May 5","Calvo SE, Pagliarini DJ, Mootha VK"
3241d3509
< "Q9CQG3-1","15950311","Immunohistochemical distribution of MIZIP and its co-expression with the Melanin-concentrating hormone receptor 1 in the adult rodent brain.","Brain research. Molecular brain research","2005 Sep 13","Francke F, Richter D, Bachner D"
3249a3518,3520
> "Q3UZ39-1","24690174","Higher LRRFIP1 expression in glioblastoma multiforme is associated with better response to teniposide, a type II topoisomerase inhibitor.","Biochemical and biophysical research communications","2014 Apr 18","Li WQ, Yu HY, Li YM, Wang X, He J, Yan HZ, Yang DH, Wu XJ, Hou LJ, Liu HM, Xia CY, Lu YC"
> "Q3UZ39-1","20586614","Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response.","Journal of interferon &amp; cytokine research : the official journal of the International Society for Interferon and Cytokine Research","2010 Nov","Bagashev A, Fitzgerald MC, Larosa DF, Rose PP, Cherry S, Johnson AC, Sullivan KE"
> "Q3UZ39-1","20453844","The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway.","Nature immunology","2010 Jun","Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X"
3257,3263c3528,3529
< "Q80TQ2-1","29291351","The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.","Nature medicine","2018 Feb","Ji YX, Huang Z, Yang X, Wang X, Zhao LP, Wang PX, Zhang XJ, Alves-Bezerra M, Cai L, Zhang P, Lu YX, Bai L, Gao MM, Zhao H, Tian S, Wang Y, Huang ZX, Zhu XY, Zhang Y, Gong J, She ZG, Li F, Cohen DE, Li H"
< "Q80TQ2-1","29259980","CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-kappaB Inflammatory Signaling in Mesangial Cells.","BioMed research international","2017","Li Y, Huang W, Xu Y, Zhou L, Liang Y, Gao C, Long Y, Xu Y"
< "Q80TQ2-1","17392286","Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells.","The Journal of biological chemistry","2007 May 25","Jin W, Reiley WR, Lee AJ, Wright A, Wu X, Zhang M, Sun SC"
< "Q80TQ2-1","17053834","Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.","The Journal of clinical investigation","2006 Nov","Zhang J, Stirling B, Temmerman ST, Ma CA, Fuss IJ, Derry JM, Jain A"
< "Q80TQ2-1","16713561","Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling.","Cell","2006 May 19","Massoumi R, Chmielarska K, Hennecke K, Pfeifer A, Fassler R"
< "Q80TQ2-1","16501569","Regulation of T cell development by the deubiquitinating enzyme CYLD.","Nature immunology","2006 Apr","Reiley WW, Zhang M, Jin W, Losiewicz M, Donohue KB, Norbury CC, Sun SC"
< "Q80TQ2-1","15226292","NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway.","The Journal of biological chemistry","2004 Aug 27","Jono H, Lim JH, Chen LF, Xu H, Trompouki E, Pan ZK, Mosialos G, Li JD"
---
> "Q8CJG1-1","26995025","Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells.","International immunopharmacology","2016 May","Zheng Y, Guo X, He W, Shao Z, Zhang X, Yang J, Shen Y, Luo X, Cao J"
> "Q80X71-1","30013069","TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins.","Nature communications","2018 Jul 16","Kundu ST, Grzeskowiak CL, Fradette JJ, Gibson LA, Rodriguez LB, Creighton CJ, Scott KL, Gibbons DL"
3268,3269d3533
< "Q80UG5-1","27939986","Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis.","Toxicology and applied pharmacology","2017 Jan 15","Wu Y, Bu F, Yu H, Li W, Huang C, Meng X, Zhang L, Ma T, Li J"
< "Q80UG5-1","23644740","Septin9 is involved in T-cell development and CD8+ T-cell homeostasis.","Cell and tissue research","2013 Jun","Lassen LB, Fuchtbauer A, Schmitz A, Sorensen AB, Pedersen FS, Fuchtbauer EM"
3274a3539
> "Q9CR56-1","20639196","KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.","The Journal of biological chemistry","2010 Oct 1","Tago K, Funakoshi-Tago M, Sakinawa M, Mizuno N, Itoh H"
3279a3545,3551
> "O54804-1","26125130","The hepatic circadian clock regulates the choline kinase alpha gene through the BMAL1-REV-ERBalpha axis.","Chronobiology international","2015","Grechez-Cassiau A, Feillet C, Guerin S, Delaunay F"
> "O54804-1","20525991","Phosphatidylcholine biosynthesis during neuronal differentiation and its role in cell fate determination.","The Journal of biological chemistry","2010 Aug 13","Marcucci H, Paoletti L, Jackowski S, Banchio C"
> "O54804-1","20026284","Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse.","Biochimica et biophysica acta","2010 Apr","Wu G, Sher RB, Cox GA, Vance DE"
> "O54804-1","18029352","Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis.","The Journal of biological chemistry","2008 Jan 18","Wu G, Aoyama C, Young SG, Vance DE"
> "O54804-1","17728180","Induction of choline kinase alpha by carbon tetrachloride (CCl4) occurs via increased binding of c-jun to an AP-1 element.","Biochimica et biophysica acta","2007 Sep","Aoyama C, Ishidate K, Sugimoto H, Vance DE"
> "O54804-1","16490392","Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta.","Biochimica et biophysica acta","2006 Jan","Liao H, Aoyama C, Ishidate K, Teraoka H"
> "O54804-1","11964179","Expression and characterization of the active molecular forms of choline/ethanolamine kinase-alpha and -beta in mouse tissues, including carbon tetrachloride-induced liver.","The Biochemical journal","2002 May 1","Aoyama C, Ohtani A, Ishidate K"
3282a3555,3560
> "A2AKQ0-1","17952091","Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human.","Nature medicine","2007 Nov","Hiraoka S, Furuichi T, Nishimura G, Shibata S, Yanagishita M, Rimoin DL, Superti-Furga A, Nikkels PG, Ogawa M, Katsuyama K, Toyoda H, Kinoshita-Toyoda A, Ishida N, Isono K, Sanai Y, Cohn DH, Koseki H, Ikegawa S"
> "Q4U4S6-1","25772365","XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia.","Cell reports","2015 Mar 24","Scheffer DI, Zhang DS, Shen J, Indzhykulian A, Karavitaki KD, Xu YJ, Wang Q, Lin JJ, Chen ZY, Corey DP"
> "Q4U4S6-1","25653358","A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Feb 4","Francis SP, Krey JF, Krystofiak ES, Cui R, Nanda S, Xu W, Kachar B, Barr-Gillespie PG, Shin JB"
> "Q4U4S6-1","23261932","The Xin repeat-containing protein, mXinbeta, initiates the maturation of the intercalated discs during postnatal heart development.","Developmental biology","2013 Feb 15","Wang Q, Lin JL, Chan SY, Lin JJ"
> "Q4U4S6-1","17046827","Myomaxin is a novel transcriptional target of MEF2A that encodes a Xin-related alpha-actinin-interacting protein.","The Journal of biological chemistry","2006 Dec 22","Huang HT, Brand OM, Mathew M, Ignatiou C, Ewen EP, McCalmon SA, Naya FJ"
> "Q4U4S6-1","16500513","A novel gene (Cmya3) induced in the heart by angiotensin II-dependent but not salt-dependent hypertension in mice.","American journal of hypertension","2006 Mar","Duka A, Schwartz F, Duka I, Johns C, Melista E, Gavras I, Gavras H"
3284,3290d3561
< "Q8C1B7-1","21824005","Lethal phenotype of mice carrying a Sept11 null mutation.","Biological chemistry","2011 Aug","Roseler S, Sandrock K, Bartsch I, Busse A, Omran H, Loges NT, Zieger B"
< "B2RPY5-1","29386106","Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.","Cell reports","2018 Jan 30","Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S"
< "B2RPY5-1","29222391","The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.","Development (Cambridge, England)","2018 Jan 8","Hwang SH, White KA, Somatilaka BN, Shelton JM, Richardson JA, Mukhopadhyay S"
< "Q3UUV5-1","27181093","T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice.","Immunology letters","2016 Aug","Smith X, Taylor A, Rudd CE"
< "Q3UUV5-1","26905930","Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.","Immunology letters","2016 Apr","Lim D, Lu Y, Rudd CE"
< "Q3UUV5-1","25851535","ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy.","EMBO molecular medicine","2015 Jun","Li C, Li W, Xiao J, Jiao S, Teng F, Xue S, Zhang C, Sheng C, Leng Q, Rudd CE, Wei B, Wang H"
< "Q3UUV5-1","17646386","Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion.","Molecular and cellular biology","2007 Oct","Wang H, Liu H, Lu Y, Lovatt M, Wei B, Rudd CE"
3292c3563,3564
< "Q9D9R7-1","16488114","Male-biased expression of X-chromosomal DM domain-less Dmrt8 genes in the mouse.","Genomics","2006 Aug","Veith AM, Klattig J, Dettai A, Schmidt C, Englert C, Volff JN"
---
> "Q8CHH9-1","27084579","SEPT8 modulates beta-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.","Journal of cell science","2016 Jun 1","Kurkinen KM, Marttinen M, Turner L, Natunen T, Makinen P, Haapalinna F, Sarajarvi T, Gabbouj S, Kurki M, Paananen J, Koivisto AM, Rauramaa T, Leinonen V, Tanila H, Soininen H, Lucas FR, Haapasalo A, Hiltunen M"
> "Q8CHH9-1","21770032","Proteins linked to extinction in contextual fear conditioning in the C57BL/6J mouse.","Proteomics","2011 Sep","Li L, Boddul SV, Patil SS, Zheng JF, An G, Hoger H, Lubec G"
3295a3568
> "Q9WUT7-1","10229797","Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.","Journal of immunology (Baltimore, Md. : 1950)","1999 May 15","Zaballos A, Gutierrez J, Varona R, Ardavin C, Marquez G"
3297,3298d3569
< "Q99LJ7-1","25762510","RC/BTB2 is essential for formation of primary cilia in mammalian cells.","Cytoskeleton (Hoboken, N.J.)","2015 Apr","Zhang L, Li W, Ni J, Wu J, Liu J, Zhang Z, Zhang Y, Li H, Shi Y, Teves ME, Song S, Strauss JF 3rd, Zhang Z"
< "Q99LJ7-1","22768142","Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles.","PloS one","2012","Wang J, Teves ME, Shen X, Nagarkatti-Gude DR, Hess RA, Henderson SC, Strauss JF 3rd, Zhang Z"
3306a3578
> "Q8BTI9-1","12869549","Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages.","The Journal of biological chemistry","2003 Oct 3","Leverrier Y, Okkenhaug K, Sawyer C, Bilancio A, Vanhaesebroeck B, Ridley AJ"
3312c3584,3585
< "Q80UW0-1","15499561","Differential expression of heparan sulfate 6-O-sulfotransferase isoforms in the mouse embryo suggests distinctive roles during organogenesis.","Developmental dynamics : an official publication of the American Association of Anatomists","2004 Dec","Sedita J, Izvolsky K, Cardoso WV"
---
> "P63242-1","26037925","Biological Relevance and Therapeutic Potential of the Hypusine Modification System.","The Journal of biological chemistry","2015 Jul 24","Pallmann N, Braig M, Sievert H, Preukschas M, Hermans-Borgmeyer I, Schweizer M, Nagel CH, Neumann M, Wild P, Haralambieva E, Hagel C, Bokemeyer C, Hauber J, Balabanov S"
> "Q9D180-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
3316a3590
> "Q61179-1","29317535","Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.","Proceedings of the National Academy of Sciences of the United States of America","2018 Jan 23","Rengachari S, Groiss S, Devos JM, Caron E, Grandvaux N, Panne D"
3325a3600
> "O70546-1","30006524","UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma.","Nature communications","2018 Jul 13","Li X, Zhang Y, Zheng L, Liu M, Chen CD, Jiang H"
3328a3604,3606
> "O08715-1","29388469","Akap1 genetic deletion increases the severity of hyperoxia-induced acute lung injury in mice.","American journal of physiology. Lung cellular and molecular physiology","2018 May 1","Narala VR, Fukumoto J, Hernandez-Cuervo H, Patil SS, Krishnamurthy S, Breitzig M, Galam L, Soundararajan R, Lockey RF, Kolliputi N"
> "O08715-1","28569781","Mitochondrial AKAP1 supports mTOR pathway and tumor growth.","Cell death &amp; disease","2017 Jun 1","Rinaldi L, Sepe M, Delle Donne R, Conte K, Arcella A, Borzacchiello D, Amente S, De Vita F, Porpora M, Garbi C, Oliva MA, Procaccini C, Faicchia D, Matarese G, Zito Marino F, Rocco G, Pignatiello S, Franco R, Insabato L, Majello B, Feliciello A"
> "O08715-1","28500286","A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation.","Scientific reports","2017 May 12","Brackley AD, Gomez R, Guerrero KA, Akopian AN, Glucksman MJ, Du J, Carlton SM, Jeske NA"
3332a3611,3615
> "Q9D9T6-1","27053129","Identification of host proteins, Spata3 and Dkk2, interacting with Toxoplasma gondii micronemal protein MIC3.","Parasitology research","2016 Jul","Wang Y, Fang R, Yuan Y, Pan M, Hu M, Zhou Y, Shen B, Zhao J"
> "Q9D9T6-1","18551385","Molecular cloning and characterization of a novel transcript variant of Mtsarg1 gene.","Molecular biology reports","2009 May","Li L, Liu G, Fu JJ, Li LY, Tan XJ, Yang S, Lu GX"
> "O70263-1","29121065","Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.","PloS one","2017","Lenihan JA, Saha O, Young PW"
> "O70263-1","19295125","The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells.","Journal of cell science","2009 Apr 1","Takahashi S, Iwamoto N, Sasaki H, Ohashi M, Oda Y, Tsukita S, Furuse M"
> "O70263-1","12468544","The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).","The Journal of biological chemistry","2003 Feb 28","Sollerbrant K, Raschperger E, Mirza M, Engstrom U, Philipson L, Ljungdahl PO, Pettersson RF"
3336,3337d3618
< "Q8R3V5-4","28455444","Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection.","The Journal of biological chemistry","2017 Jun 16","Serfass JM, Takahashi Y, Zhou Z, Kawasawa YI, Liu Y, Tsotakos N, Young MM, Tang Z, Yang L, Atkinson JM, Chroneos ZC, Wang HG"
< "Q8R3V5-4","18303116","SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade.","Proceedings of the National Academy of Sciences of the United States of America","2008 Mar 4","Fasso M, Waitz R, Hou Y, Rim T, Greenberg NM, Shastri N, Fong L, Allison JP"
3339d3619
< "P48540-1","30651543","Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback.","Nature communications","2019 Jan 16","Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D"
3345,3347c3625,3626
< "Q9D486-1","27650733","Repression of CMIP transcription by WT1 is relevant to podocyte health.","Kidney international","2016 Dec","Moktefi A, Zhang SY, Vachin P, Ory V, Henique C, Audard V, Rucker-Martin C, Gouadon E, Eccles M, Schedl A, Heidet L, Ollero M, Sahali D, Pawlak A"
< "Q9D486-1","23200848","Inhibition of nephrin activation by c-mip through Csk-Cbp-Fyn axis plays a critical role in Angiotensin II-induced podocyte damage.","Cellular signalling","2013 Mar","Yu L, Lin Q, Feng J, Dong X, Chen W, Liu Q, Ye J"
< "Q9D486-1","20808911","A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.","PloS one","2010 Aug 17","Li Z, Mulligan MK, Wang X, Miles MF, Lu L, Williams RW"
---
> "Q80UG5-1","27939986","Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis.","Toxicology and applied pharmacology","2017 Jan 15","Wu Y, Bu F, Yu H, Li W, Huang C, Meng X, Zhang L, Ma T, Li J"
> "Q80UG5-1","23644740","Septin9 is involved in T-cell development and CD8+ T-cell homeostasis.","Cell and tissue research","2013 Jun","Lassen LB, Fuchtbauer A, Schmitz A, Sorensen AB, Pedersen FS, Fuchtbauer EM"
3348a3628,3631
> "Q7TPD1-1","27166359","FBXO11 inactivation leads to abnormal germinal-center formation and lymphoproliferative disease.","Blood","2016 Aug 4","Schneider C, Kon N, Amadori L, Shen Q, Schwartz FH, Tischler B, Bossennec M, Dominguez-Sola D, Bhagat G, Gu W, Basso K, Dalla-Favera R"
> "Q7TPD1-1","26471094","Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.","Disease models &amp; mechanisms","2015 Dec","Tateossian H, Morse S, Simon MM, Dean CH, Brown SD"
> "Q9CSU0-1","28893536","CREPT regulated by miR-138 promotes breast cancer progression.","Biochemical and biophysical research communications","2017 Nov 4","Liang Z, Feng Q, Xu L, Li S, Zhou L"
> "Q9CSU0-1","24982424","CREPT/RPRD1B, a recently identified novel protein highly expressed in tumors, enhances the beta-catenin.TCF4 transcriptional activity in response to Wnt signaling.","The Journal of biological chemistry","2014 Aug 15","Zhang Y, Liu C, Duan X, Ren F, Li S, Jin Z, Wang Y, Feng Y, Liu Z, Chang Z"
3360a3644,3650
> "Q8BXR9-1","26941018","miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux.","Arteriosclerosis, thrombosis, and vascular biology","2016 May","Ouimet M, Hennessy EJ, van Solingen C, Koelwyn GJ, Hussein MA, Ramkhelawon B, Rayner KJ, Temel RE, Perisic L, Hedin U, Maegdefessel L, Garabedian MJ, Holdt LM, Teupser D, Moore KJ"
> "Q8K558-1","30120105","TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice.","Blood advances","2018 Aug 28","Smith CW, Raslan Z, Parfitt L, Khan AO, Patel P, Senis YA, Mazharian A"
> "Q8K558-1","22761415","TLT-1s, alternative transcripts of triggering receptor expressed on myeloid cell-like transcript-1 (TLT-1), Inhibits the triggering receptor expressed on myeloid cell-2 (TREM-2)-mediated signaling pathway during osteoclastogenesis.","The Journal of biological chemistry","2012 Aug 24","Yoon SH, Lee YD, Ha J, Lee Y, Kim HH"
> "Q8K558-1","19436112","TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.","The Journal of clinical investigation","2009 Jun","Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, Lubkowski J, Hunter R, Schwartzberg PL, McVicar DW"
> "Q8K558-1","16505478","The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment.","The Journal of biological chemistry","2006 May 12","Gattis JL, Washington AV, Chisholm MM, Quigley L, Szyk A, McVicar DW, Lubkowski J"
> "Q8K558-1","15100151","A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets.","Blood","2004 Aug 15","Washington AV, Schubert RL, Quigley L, Disipio T, Feltz R, Cho EH, McVicar DW"
> "Q8K558-1","12393607","Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster.","Blood","2002 Nov 15","Washington AV, Quigley L, McVicar DW"
3362a3653,3657
> "Q09200-1","30521973","Loss of Enzyme Activity in Mutated B4GALNT1 Gene Products in Patients with Hereditary Spastic Paraplegia Results in Relatively Mild Neurological Disorders: Similarity with Phenotypes of B4galnt1 Knockout Mice.","Neuroscience","2019 Jan 15","Bhuiyan RH, Ohmi Y, Ohkawa Y, Zhang P, Takano M, Hashimoto N, Okajima T, Furukawa K, Furukawa K"
> "P70170-1","28121062","Exposure to 15% oxygen in vivo up-regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK.","Journal of cellular and molecular medicine","2017 Jul","Mohammed Abdul KS, Jovanovic S, Jovanovic A"
> "P70170-1","27086859","Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse.","The Journal of veterinary medical science","2016 Aug 1","Hong SH, Kyeong KS, Kim CH, Kim YC, Choi W, Yoo RY, Kim HS, Park YJ, Ji IW, Jeong EH, Kim HS, Xu WX, Lee SJ"
> "P12849-1","30541888","Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.","Proceedings of the National Academy of Sciences of the United States of America","2018 Dec 26","Mathieu M, Drelon C, Rodriguez S, Tabbal H, Septier A, Damon-Soubeyrand C, Dumontet T, Berthon A, Sahut-Barnola I, Djari C, Batisse-Lignier M, Pointud JC, Richard D, Kerdivel G, Calmejane MA, Boeva V, Tauveron I, Lefrancois-Martinez AM, Martinez A, Val P"
> "Q07409-1","27539848","Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.","The Journal of biological chemistry","2016 Oct 7","Nikolaienko RM, Hammel M, Dubreuil V, Zalmai R, Hall DR, Mehzabeen N, Karuppan SJ, Harroch S, Stella SL, Bouyain S"
3363a3659
> "Q9D9J2-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
3366a3663,3665
> "Q80X66-1","18160256","A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB.","Cellular signalling","2008 Mar","Nawa M, Kanekura K, Hashimoto Y, Aiso S, Matsuoka M"
> "Q6NWV3-1","30476139","C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization.","Journal of biochemistry","2019 Mar 1","Takahara M, Kunii M, Nakamura K, Harada A, Hirano T, Katoh Y, Nakayama K"
> "Q6NWV3-1","19000668","Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.","Developmental biology","2009 Jan 1","Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A"
3370a3670,3671
> "Q8BH69-1","16262699","Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans.","The FEBS journal","2005 Nov","Saiki R, Nagata A, Kainou T, Matsuda H, Kawamukai M"
> "Q8BGQ1-1","29409756","VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function.","Biochimica et biophysica acta. Molecular basis of disease","2018 May","Rogerson C, Gissen P"
3379a3681
> "Q91X58-1","26692333","Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.","Nature medicine","2016 Jan","Osorio FG, Soria-Valles C, Santiago-Fernandez O, Bernal T, Mittelbrunn M, Colado E, Rodriguez F, Bonzon-Kulichenko E, Vazquez J, Porta-de-la-Riva M, Ceron J, Fueyo A, Li J, Green AR, Freije JM, Lopez-Otin C"
3391d3692
< "Q64516-3","19546021","Weighted gene co-expression network analysis identifies biomarkers in glycerol kinase deficient mice.","Molecular genetics and metabolism","2009 Sep-Oct","MacLennan NK, Dong J, Aten JE, Horvath S, Rahib L, Ornelas L, Dipple KM, McCabe ER"
3393d3693
< "Q80X50-1","25185265","UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.","Blood","2014 Oct 9","Bordeleau ME, Aucagne R, Chagraoui J, Girard S, Mayotte N, Bonneil E, Thibault P, Pabst C, Bergeron A, Barabe F, Hebert J, Sauvageau M, Boutonnet C, Meloche S, Sauvageau G"
3395c3695,3696
< "Q80TY0-1","15252009","A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis.","The Journal of biological chemistry","2004 Sep 17","Kamioka Y, Fukuhara S, Sawa H, Nagashima K, Masuda M, Matsuda M, Mochizuki N"
---
> "O08524-1","28935705","A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane.","Development (Cambridge, England)","2017 Nov 1","Goodyear RJ, Lu X, Deans MR, Richardson GP"
> "O08524-1","26806019","Tectorins crosslink type II collagen fibrils and connect the tectorial membrane to the spiral limbus.","Journal of structural biology","2016 May","Andrade LR, Salles FT, Grati M, Manor U, Kachar B"
3400d3700
< "Q3TPJ7-1","24187134","Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner.","The Journal of biological chemistry","2013 Dec 13","Hofmeister-Brix A, Kollmann K, Langer S, Schultz J, Lenzen S, Baltrusch S"
3406a3707
> "A2AU37-1","21527826","Identification and molecular characterization of the mammalian alpha-kleisin RAD21L.","Cell cycle (Georgetown, Tex.)","2011 May 1","Gutierrez-Caballero C, Herran Y, Sanchez-Martin M, Suja JA, Barbero JL, Llano E, Pendas AM"
3408a3710,3712
> "Q99K48-1","29673854","Silencing of Non-POU-domain-containing octamer-binding protein stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice via NF-kappaB signaling pathway.","International journal of cardiology","2018 Jul 15","Zhang K, Zhang F, Yang JM, Kong J, Meng X, Zhang M, Zhang C, Zhang Y"
> "Q99K48-1","29358041","The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding.","Cell metabolism","2018 Feb 6","Benegiamo G, Mure LS, Erikson G, Le HD, Moriggi E, Brown SA, Panda S"
> "Q99K48-1","28209515","Cell-type specific role of the RNA-binding protein, NONO, in the DNA double-strand break response in the mouse testes.","DNA repair","2017 Mar","Li S, Shu FJ, Li Z, Jaafar L, Zhao S, Dynan WS"
3410,3415d3713
< "Q8K558-1","30120105","TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice.","Blood advances","2018 Aug 28","Smith CW, Raslan Z, Parfitt L, Khan AO, Patel P, Senis YA, Mazharian A"
< "Q8K558-1","22761415","TLT-1s, alternative transcripts of triggering receptor expressed on myeloid cell-like transcript-1 (TLT-1), Inhibits the triggering receptor expressed on myeloid cell-2 (TREM-2)-mediated signaling pathway during osteoclastogenesis.","The Journal of biological chemistry","2012 Aug 24","Yoon SH, Lee YD, Ha J, Lee Y, Kim HH"
< "Q8K558-1","19436112","TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.","The Journal of clinical investigation","2009 Jun","Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, Lubkowski J, Hunter R, Schwartzberg PL, McVicar DW"
< "Q8K558-1","16505478","The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment.","The Journal of biological chemistry","2006 May 12","Gattis JL, Washington AV, Chisholm MM, Quigley L, Szyk A, McVicar DW, Lubkowski J"
< "Q8K558-1","15100151","A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets.","Blood","2004 Aug 15","Washington AV, Schubert RL, Quigley L, Disipio T, Feltz R, Cho EH, McVicar DW"
< "Q8K558-1","12393607","Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster.","Blood","2002 Nov 15","Washington AV, Quigley L, McVicar DW"
3420a3719
> "Q8R3L2-1","12107429","Nulp1, a novel basic helix-loop-helix protein expressed broadly during early embryonic organogenesis and prominently in developing dorsal root ganglia.","Cell and tissue research","2002 Jun","Olsson M, Durbeej M, Ekblom P, Hjalt T"
3429a3729,3731
> "Q9D552-1","16395525","Expression and identification of a novel apoptosis gene Spata17 (MSRG-11) in mouse spermatogenic cells.","Acta biochimica et biophysica Sinica","2006 Jan","Deng Y, Hu LS, Lu GX"
> "Q9DCG2-1","27316686","Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration.","Journal of immunology (Baltimore, Md. : 1950)","2016 Aug 1","Lo TH, Silveira PA, Fromm PD, Verma ND, Vu PA, Kupresanin F, Adam R, Kato M, Cogger VC, Clark GJ, Hart DN"
> "Q9DCG2-1","17947679","The novel endocytic and phagocytic C-Type lectin receptor DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting a role in cell adhesion and migration.","Journal of immunology (Baltimore, Md. : 1950)","2007 Nov 1","Kato M, Khan S, d'Aniello E, McDonald KJ, Hart DN"
3431a3734,3735
> "Q8CFW1-1","19474308","TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2009 May 27","Stohr H, Heisig JB, Benz PM, Schoberl S, Milenkovic VM, Strauss O, Aartsen WM, Wijnholds J, Weber BH, Schulz HL"
> "Q8CFW1-1","18729231","Expression of TMEM16 paralogs during murine embryogenesis.","Developmental dynamics : an official publication of the American Association of Anatomists","2008 Sep","Rock JR, Harfe BD"
3436,3439c3740
< "Q8BH75-1","26390156","K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8(+) T cell activation.","Nature immunology","2015 Dec","Yang M, Chen T, Li X, Yu Z, Tang S, Wang C, Gu Y, Liu Y, Xu S, Li W, Zhang X, Wang J, Cao X"
< "Q8BH75-1","26085571","Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in beta-Cells.","Diabetes","2015 Oct","Soleimanpour SA, Ferrari AM, Raum JC, Groff DN, Yang J, Kaufman BA, Stoffers DA"
< "Q8BH75-1","22707723","The E3 ubiquitin ligase neuregulin receptor degradation protein 1 (Nrdp1) promotes M2 macrophage polarization by ubiquitinating and activating transcription factor CCAAT/enhancer-binding Protein beta (C/EBPbeta).","The Journal of biological chemistry","2012 Aug 3","Ye S, Xu H, Jin J, Yang M, Wang C, Yu Y, Cao X"
< "Q8BH75-1","21738612","Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in mice.","PloS one","2011","Zhang Y, Kang YM, Tian C, Zeng Y, Jia LX, Ma X, Du J, Li HH"
---
> "Q924M5-1","24086306","A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.","PloS one","2013","He J, Stewart K, Kinnell HL, Anderson RA, Childs AJ"
3446a3748,3749
> "Q924A2-4","29382756","Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.","Proceedings of the National Academy of Sciences of the United States of America","2018 Feb 13","Tan Q, Brunetti L, Rousseaux MWC, Lu HC, Wan YW, Revelli JP, Liu Z, Goodell MA, Zoghbi HY"
> "Q924A2-4","12393275","CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons.","Brain research. Molecular brain research","2002 Oct 15","Lee CJ, Chan WI, Cheung M, Cheng YC, Appleby VJ, Orme AT, Scotting PJ"
3448a3752,3753
> "P70662-1","30873428","LDB1 Is Required for the Early Development of the Dorsal Telencephalon and the Thalamus.","eNeuro","2019 Jan-Feb","Kinare V, Pal S, Tole S"
> "P70662-1","16815859","Spliced isoforms of LIM-domain-binding protein (CLIM/NLI/Ldb) lacking the LIM-interaction domain.","Journal of biochemistry","2006 Jul","Tran YH, Xu Z, Kato A, Mistry AC, Goya Y, Taira M, Brandt SJ, Hirose S"
3450,3452d3754
< "Q14AX6-1","27073218","Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.","Cerebral cortex (New York, N.Y. : 1991)","2017 Mar 1","Chen HR, Juan HC, Wong YH, Tsai JW, Fann MJ"
< "Q14AX6-1","26658019","Cdk12 is essential for embryonic development and the maintenance of genomic stability.","Cell death and differentiation","2016 Jun","Juan HC, Lin Y, Chen HR, Fann MJ"
< "Q14AX6-1","24999027","Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.","Experimental neurology","2014 Nov","Chen HR, Lin GT, Huang CK, Fann MJ"
3463d3764
< "Q9JI90-1","24472305","RNF14 is a regulator of mitochondrial and immune function in muscle.","BMC systems biology","2014 Jan 29","Ingham AB, Osborne SA, Menzies M, Briscoe S, Chen W, Kongsuwan K, Reverter A, Jeanes A, Dalrymple BP, Wijffels G, Seymour R, Hudson NJ"
3475d3775
< "P58269-1","18765789","Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.","Genes &amp; development","2008 Sep 1","Lange M, Kaynak B, Forster UB, Tonjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S"
3479,3480c3779,3782
< "Q3UHD6-1","27974614","SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2016 Dec 14","Wang X, Zhou Y, Wang J, Tseng IC, Huang T, Zhao Y, Zheng Q, Gao Y, Luo H, Zhang X, Bu G, Hong W, Xu H"
< "Q3UHD6-1","15466885","New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.","Journal of cell science","2004 Oct 15","Joubert L, Hanson B, Barthet G, Sebben M, Claeysen S, Hong W, Marin P, Dumuis A, Bockaert J"
---
> "Q8BKH7-1","28692058","Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma.","Oncogene","2017 Nov 9","Wang Q, Zhu J, Wang YW, Dai Y, Wang YL, Wang C, Liu J, Baker A, Colburn NH, Yang HS"
> "Q8BKH7-1","28174303","Central Regulatory Role for SIN1 in Interferon gamma (IFNgamma) Signaling and Generation of Biological Responses.","The Journal of biological chemistry","2017 Mar 17","Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EN, Platanias LC"
> "Q8BKH7-1","17043309","Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.","Genes &amp; development","2006 Oct 15","Yang Q, Inoki K, Ikenoue T, Guan KL"
> "Q8BKH7-1","16962653","SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.","Cell","2006 Oct 6","Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B"
3488a3791,3796
> "Q80TJ1-1","28883501","CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.","Scientific reports","2017 Sep 7","van Keimpema L, Kooistra R, Toonen RF, Verhage M"
> "Q80TJ1-1","16506193","Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain.","The Journal of comparative neurology","2006 Apr 20","Sadakata T, Itakura M, Kozaki S, Sekine Y, Takahashi M, Furuichi T"
> "Q9JHL0-1","25153696","Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology.","PloS one","2014","Polakovicova I, Draberova L, Simicek M, Draber P"
> "Q9JHL0-1","24819605","Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation.","PloS one","2014","Nunez B, Martinez de Mena R, Obregon MJ, Font-Llitjos M, Nunes V, Palacin M, Dumitrescu AM, Morte B, Bernal J"
> "Q9JHL0-1","23675302","LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-gamma production by repressing beta-catenin activation in dendritic cells.","PLoS pathogens","2013 May","Orr SJ, Burg AR, Chan T, Quigley L, Jones GW, Ford JW, Hodge D, Razzook C, Sarhan J, Jones YL, Whittaker GC, Boelte KC, Lyakh L, Cardone M, O'Connor GM, Tan C, Li H, Anderson SK, Jones SA, Zhang W, Taylor PR, Trinchieri G, McVicar DW"
> "Q9JHL0-1","15477348","Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.","The Journal of experimental medicine","2004 Oct 18","Volna P, Lebduska P, Draberova L, Simova S, Heneberg P, Boubelik M, Bugajev V, Malissen B, Wilson BS, Horejsi V, Malissen M, Draber P"
3492,3496d3799
< "Q149L7-1","26694968","CRTAM determines the CD4+ cytotoxic T lymphocyte lineage.","The Journal of experimental medicine","2016 Jan 11","Takeuchi A, Badr Mel S, Miyauchi K, Ishihara C, Onishi R, Guo Z, Sasaki Y, Ike H, Takumi A, Tsuji NM, Murakami Y, Katakai T, Kubo M, Saito T"
< "Q149L7-1","24687959","CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection.","The Journal of experimental medicine","2014 Apr 7","Cortez VS, Cervantes-Barragan L, Song C, Gilfillan S, McDonald KG, Tussiwand R, Edelson BT, Murakami Y, Murphy KM, Newberry RD, Sibley LD, Colonna M"
< "Q149L7-1","21572449","Trichosanthin enhances anti-tumor immune response in a murine Lewis lung cancer model by boosting the interaction between TSLC1 and CRTAM.","Cellular &amp; molecular immunology","2011 Jul","Cai Y, Xiong S, Zheng Y, Luo F, Jiang P, Chu Y"
< "Q149L7-1","15811952","The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.","Blood","2005 Aug 1","Boles KS, Barchet W, Diacovo T, Cella M, Colonna M"
< "Q149L7-1","15781451","Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.","The Journal of biological chemistry","2005 Jun 10","Galibert L, Diemer GS, Liu Z, Johnson RS, Smith JL, Walzer T, Comeau MR, Rauch CT, Wolfson MF, Sorensen RA, Van der Vuurst de Vries AR, Branstetter DG, Koelling RM, Scholler J, Fanslow WC, Baum PR, Derry JM, Yan W"
3500a3804
> "Q91Y74-1","12097641","Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.","Proceedings of the National Academy of Sciences of the United States of America","2002 Jul 23","Ellies LG, Ditto D, Levy GG, Wahrenbrock M, Ginsburg D, Varki A, Le DT, Marth JD"
3506a3811
> "O89110-1","30598363","RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.","Molecular cell","2019 Feb 7","Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schunke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P"
3507a3813,3815
> "Q9Z1N5-1","29164525","Heat shock factor 4 regulates the expression of HSP25 and alpha B-crystallin by associating with DEXD/H-box RNA helicase UAP56.","Cell stress &amp; chaperones","2018 Jul","Cui X, Han W, Li J, Feng R, Zhou Z, Han J, Li M, Wang S, Zhang W, Lei Q, Zhang J, Liu Y, Hu Y"
> "Q9Z1N5-1","24618812","Murine leukemia virus uses TREX components for efficient nuclear export of unspliced viral transcripts.","Viruses","2014 Mar 10","Sakuma T, Tonne JM, Ikeda Y"
> "P97465-1","29548825","Dok-3 and Dok-1/-2 adaptors play distinctive roles in cell fusion and proliferation during osteoclastogenesis and cooperatively protect mice from osteopenia.","Biochemical and biophysical research communications","2018 Apr 15","Kajikawa S, Taguchi Y, Hayata T, Ezura Y, Ueta R, Arimura S, Inoue JI, Noda M, Yamanashi Y"
3508a3817
> "Q5DTY9-1","21452234","Distribution of the auxiliary GABAB receptor subunits KCTD8, 12, 12b, and 16 in the mouse brain.","The Journal of comparative neurology","2011 Jun 1","Metz M, Gassmann M, Fakler B, Schaeren-Wiemers N, Bettler B"
3510,3519c3819,3824
< "Q7TSC3-1","23727203","Nek5, a novel substrate for caspase-3, promotes skeletal muscle differentiation by up-regulating caspase activity.","FEBS letters","2013 Jul 11","Shimizu K, Sawasaki T"
< "Q8BR86-1","29362445","Abnormal behaviours relevant to neurodevelopmental disorders in Kirrel3-knockout mice.","Scientific reports","2018 Jan 23","Hisaoka T, Komori T, Kitamura T, Morikawa Y"
< "Q8BR86-1","28815295","Loss of Kirrel family members alters glomerular structure and synapse numbers in the accessory olfactory bulb.","Brain structure &amp; function","2018 Jan","Brignall AC, Raja R, Phen A, Prince JEA, Dumontier E, Cloutier JF"
< "Q8BR86-1","28670619","Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice.","eNeuro","2017 May-Jun","Martin EA, Woodruff D, Rawson RL, Williams ME"
< "Q8BR86-1","28621431","Adhesion molecule Kirrel3/Neph2 is required for the elongated shape of myocytes during skeletal muscle differentiation.","The International journal of developmental biology","2017","Tamir-Livne Y, Mubariki R, Bengal E"
< "Q8BR86-1","18752272","Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles.","The Journal of comparative neurology","2008 Nov 1","Komori T, Gyobu H, Ueno H, Kitamura T, Senba E, Morikawa Y"
< "Q8BR86-1","18022324","Expression of mKirre in the developing sensory pathways: its close apposition to nephrin-expressing cells.","Neuroscience","2007 Dec 19","Morikawa Y, Komori T, Hisaoka T, Ueno H, Kitamura T, Senba E"
< "Q8BR86-1","16874800","Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis.","The Journal of comparative neurology","2006 Oct 1","Gerke P, Benzing T, Hohne M, Kispert A, Frotscher M, Walz G, Kretz O"
< "Q8BR86-1","15908127","Expression of mKirre, a mammalian homolog of Drosophila kirre, in the developing and adult mouse brain.","Neuroscience","2005","Tamura S, Morikawa Y, Hisaoka T, Ueno H, Kitamura T, Senba E"
< "Q8BR86-1","12665856","A stromal cell-derived membrane protein that supports hematopoietic stem cells.","Nature immunology","2003 May","Ueno H, Sakita-Ishikawa M, Morikawa Y, Nakano T, Kitamura T, Saito M"
---
> "Q6P902-1","23707457","Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress.","Free radical biology &amp; medicine","2013 Dec","Smith TB, Baker MA, Connaughton HS, Habenicht U, Aitken RJ"
> "Q8R317-1","27928652","Enhanced Proteostasis in Post-ischemic Stroke Mouse Brains by Ubiquilin-1 Promotes Functional Recovery.","Cellular and molecular neurobiology","2017 Oct","Liu Y, Qiao F, Wang H"
> "Q8R317-1","28420763","Reduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteins.","Physiological reports","2017 Apr","Qiao F, Longley KR, Feng S, Schnack S, Gao H, Li Y, Schlenker EH, Wang H"
> "Q8R317-1","28598849","Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-beta Accumulation in Mice.","Journal of Alzheimer's disease : JAD","2017","Adegoke OO, Qiao F, Liu Y, Longley K, Feng S, Wang H"
> "Q8R317-1","19148225","PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation.","EMBO reports","2009 Feb","N'Diaye EN, Kajihara KK, Hsieh I, Morisaki H, Debnath J, Brown EJ"
> "Q8R317-1","15004330","Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins.","Journal of Alzheimer's disease : JAD","2004 Feb","Massey LK, Mah AL, Ford DL, Miller J, Liang J, Doong H, Monteiro MJ"
3532a3838,3840
> "Q3U0M1-1","20004763","A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.","American journal of human genetics","2009 Dec","Mochida GH, Mahajnah M, Hill AD, Basel-Vanagaite L, Gleason D, Hill RS, Bodell A, Crosier M, Straussberg R, Walsh CA"
> "Q3U0M1-1","19656848","mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles.","Molecular biology of the cell","2009 Oct","Yamasaki A, Menon S, Yu S, Barrowman J, Meerloo T, Oorschot V, Klumperman J, Satoh A, Ferro-Novick S"
> "Q3U0M1-1","15951441","NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation.","The Journal of biological chemistry","2005 Aug 12","Hu WH, Pendergast JS, Mo XM, Brambilla R, Bracchi-Ricard V, Li F, Walters WM, Blits B, He L, Schaal SM, Bethea JR"
3537a3846,3849
> "Q8R0Z2-1","21625959","hnRNP F directs formation of an exon 4 minus variant of tumor-associated NADH oxidase (ENOX2).","Molecular and cellular biochemistry","2011 Nov","Tang X, Kane VD, Morre DM, Morre DJ"
> "Q8R0Z2-1","18980249","Cell size increased in tissues from transgenic mice overexpressing a cell surface growth-related and cancer-specific hydroquinone oxidase, tNOX, with protein disulfide-thiol interchange activity.","Journal of cellular biochemistry","2008 Dec 15","Yagiz K, Snyder PW, Morre DJ, Morre DM"
> "Q8R0Z2-1","17115410","Mouse embryonic fibroblast cells from transgenic mice overexpressing tNOX exhibit an altered growth and drug response phenotype.","Journal of cellular biochemistry","2007 May 15","Yagiz K, Wu LY, Kuntz CP, James Morre D, Morre DM"
> "Q8BYW1-1","27566826","Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice.","Journal of immunology (Baltimore, Md. : 1950)","2016 Oct 1","Csepanyi-Komi R, Wisniewski E, Bartos B, Levai P, Nemeth T, Balazs B, Kurz AR, Bierschenk S, Sperandio M, Ligeti E"
3543a3856
> "O88829-1","28808804","Identification of a new liver-specific c-type mRNA transcriptional variant for mouse ST3GAL5 (GM3/GM4 synthase).","Glycoconjugate journal","2017 Oct","Shishido F, Uemura S, Nitta T, Inokuchi JI"
3550a3864
> "Q9R0N6-1","11751263","Synaptotagmin VIII is localized to the mouse sperm head and may function in acrosomal exocytosis.","Biology of reproduction","2002 Jan","Hutt DM, Cardullo RA, Baltz JM, Ngsee JK"
3560,3561d3873
< "Q9JJJ7-1","29066530","Regulation of porcupine-dependent Wnt signaling is essential for uterine development and function.","Reproduction (Cambridge, England)","2018 Jan","Farah O, Biechele S, Rossant J, Dufort D"
< "Q9JJJ7-1","29036275","Porcupine-dependent Wnt activity within the uterine epithelium is essential for fertility.","Biology of reproduction","2017 Nov 1","Farah O, Biechele S, Rossant J, Dufort D"
3566a3879
> "Q8BVU0-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
3574a3888
> "Q1A3B0-1","26887952","Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.","The Journal of biological chemistry","2016 Apr 1","Sassa T, Hirayama T, Kihara A"
3576,3578c3890,3893
< "Q08943-1","30344095","The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage.","Molecular cell","2018 Dec 6","Piquet S, Le Parc F, Bai SK, Chevallier O, Adam S, Polo SE"
< "Q08943-1","29953487","Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene.","PloS one","2018","Sandlesh P, Juang T, Safina A, Higgins MJ, Gurova KV"
< "Q08943-1","26842758","Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability.","Nature communications","2016 Feb 4","Husain A, Begum NA, Taniguchi T, Taniguchi H, Kobayashi M, Honjo T"
---
> "Q62406-1","30361091","Down-regulation of IRAK1 attenuates podocyte apoptosis in diabetic nephropathy through PI3K/Akt signaling pathway.","Biochemical and biophysical research communications","2018 Nov 30","Zhang Y, Chen X, Yuan L, Zhang Y, Wu J, Guo N, Chen X, Liu J"
> "Q62406-1","30078230","Globular Adiponectin Exerts a Pro-Inflammatory Effect via IkappaB/NF-kappaB Pathway Activation and Anti-Inflammatory Effect by IRAK-1 Downregulation.","Molecules and cells","2018 Aug 31","Lee KH, Jeong J, Woo J, Lee CH, Yoo CG"
> "Q62406-1","29995830","Endotoxin Tolerant Dendritic Cells Suppress Inflammatory Responses in Splenocytes via Interleukin-1 Receptor Associated Kinase (IRAK)-M and Programmed Death-Ligand 1 (PDL-1).","Medical science monitor : international medical journal of experimental and clinical research","2018 Jul 11","Zhou Y, Xia Q, Wang X, Fu S"
> "Q62406-1","29804558","Anti-inflammatory effects of a novel compound, MPQP, through the inhibition of IRAK1 signaling pathways in LPS-stimulated RAW 264.7 macrophages.","BMB reports","2018 Jun","Kim BR, Cho YC, Cho S"
3582a3898
> "Q9ESG4-1","26240152","Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin.","The Journal of biological chemistry","2015 Oct 2","Fairweather SJ, Broer A, Subramanian N, Tumer E, Cheng Q, Schmoll D, O'Mara ML, Broer S"
3591c3907
< "Q8JZL7-1","20090772","Early endosome localization and activity of RasGEF1b, a toll-like receptor-inducible Ras guanine-nucleotide exchange factor.","Genes and immunity","2010 Sep","Andrade WA, Silva AM, Alves VS, Salgado AP, Melo MB, Andrade HM, Dall'Orto FV, Garcia SA, Silveira TN, Gazzinelli RT"
---
> "Q8K3I4-1","12221080","Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin.","The Journal of biological chemistry","2002 Nov 8","Fukuda M, Kuroda TS"
3593,3594d3908
< "Q6PKN7-1","25525809","Maintenance of leukemia-initiating cells is regulated by the CDK inhibitor Inca1.","PloS one","2014","Baumer N, Baumer S, Berkenfeld F, Stehling M, Kohler G, Berdel WE, Muller-Tidow C, Tschanter P"
< "Q6PKN7-1","21540187","Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling.","The Journal of biological chemistry","2011 Aug 12","Baumer N, Tickenbrock L, Tschanter P, Lohmeyer L, Diederichs S, Baumer S, Skryabin BV, Zhang F, Agrawal-Singh S, Kohler G, Berdel WE, Serve H, Koschmieder S, Muller-Tidow C"
3596a3911,3917
> "Q61645-1","29422543","Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA.","Experimental &amp; molecular medicine","2018 Feb 9","Kim JK, Kim I, Choi K, Choi JH, Kim E, Lee HY, Park J, Kim Yoon S"
> "Q61210-1","29130930","Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.","The Journal of clinical investigation","2017 Dec 1","Carbone ML, Chadeuf G, Heurtebise-Chretien S, Prieur X, Quillard T, Goueffic Y, Vaillant N, Rio M, Castan L, Durand M, Baron-Menguy C, Aureille J, Desfrancois J, Tesse A, Torres RM, Loirand G"
> "Q61210-1","27923664","Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons.","Neuroscience letters","2017 Jan 18","Xiang X, Zhuang X, Li S, Shi L"
> "Q61210-1","27489999","Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.","FEBS letters","2016 Sep","Xiang X, Li S, Zhuang X, Shi L"
> "Q9JHG6-1","30442942","Conditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture.","Nature communications","2018 Nov 15","Villahoz S, Yunes-Leites PS, Mendez-Barbero N, Urso K, Bonzon-Kulichenko E, Ortega S, Nistal JF, Vazquez J, Offermanns S, Redondo JM, Campanero MR"
> "Q9JHG6-1","30139658","RCAN1 is a marker of oxidative stress, induced in acute pancreatitis.","Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]","2018 Oct","Norberg KJ, Nania S, Li X, Gao H, Szatmary P, Segersvard R, Haas S, Wagman A, Arnelo U, Sutton R, Heuchel RL, Lohr JM"
> "Q9JHG6-1","29799862","Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways.","PloS one","2018","Pang Z, Junkins RD, Raudonis R, MacNeil AJ, McCormick C, Cheng Z, Lin TJ"
3597a3919
> "Q99MY8-1","17544230","Trithorax-group protein ASH1 methylates histone H3 lysine 36.","Gene","2007 Aug 1","Tanaka Y, Katagiri Z, Kawahashi K, Kioussis D, Kitajima S"
3600a3923
> "Q9JJY3-1","28889482","TLR-Induced SMPD3 Defects Enhance Inflammatory Response of B Cell and Macrophage in the Pathogenesis of SLE.","Scandinavian journal of immunology","2017 Nov","Liu F, Li X, Yue H, Ji J, You M, Ding L, Fan H, Hou Y"
3602,3608d3924
< "Q9ET54-1","28739877","PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 1","Sun HM, Chen XL, Chen XJ, Liu J, Ma L, Wu HY, Huang QH, Xi XD, Yin T, Zhu J, Chen Z, Chen SJ"
< "Q9ET54-1","28340616","Lacking of palladin leads to multiple cellular events changes which contribute to NTD.","Neural development","2017 Mar 24","Tan J, Chen XJ, Shen CL, Zhang HX, Tang LY, Lu SY, Wu WT, Kuang Y, Fei J, Wang ZG"
< "Q9ET54-1","27865965","Palladin is involved in platelet activation and arterial thrombosis.","Thrombosis research","2017 Jan","Chen X, Fan X, Tan J, Shi P, Wang X, Wang J, Kuang Y, Fei J, Liu J, Dang S, Wang Z"
< "Q9ET54-1","14983521","Palladin is a novel binding partner for Ena/VASP family members.","Cell motility and the cytoskeleton","2004 May","Boukhelifa M, Parast MM, Bear JE, Gertler FB, Otey CA"
< "Q925J9-1","29293266","Med1 deficiency alters the somatic hypermutation spectrum in murine B cells.","European journal of immunology","2018 Apr","Gaudot L, Thomas-Claudepierre AS, Robert I, Schiavo E, Heyer V, Reina-San-Martin B"
< "Q925J9-1","29187405","HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1.","Cancer research","2018 Jan 15","Yang Y, Leonard M, Zhang Y, Zhao D, Mahmoud C, Khan S, Wang J, Lower EE, Zhang X"
< "Q925J9-1","28673966","Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene.","The Journal of biological chemistry","2017 Aug 18","Yoshizaki K, Hu L, Nguyen T, Sakai K, Ishikawa M, Takahashi I, Fukumoto S, DenBesten PK, Bikle DD, Oda Y, Yamada Y"
3615a3932,3933
> "P68500-1","27539848","Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.","The Journal of biological chemistry","2016 Oct 7","Nikolaienko RM, Hammel M, Dubreuil V, Zalmai R, Hall DR, Mehzabeen N, Karuppan SJ, Harroch S, Stella SL, Bouyain S"
> "Q8R5H6-1","30352064","Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice.","PloS one","2018","Chen Y, Milenkovic M, Horsfall W, Salahpour A, Soderling SH, Ramsey AJ"
3620a3939
> "B8ZXI1-1","19414587","Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase.","The Journal of biological chemistry","2009 Jul 3","Boland C, Hayes P, Santa-Maria I, Nishimura S, Kelly VP"
3623,3624d3941
< "Q8K2P6-1","21238580","Primary role of mitochondrial Rieske iron-sulfur protein in hypoxic ROS production in pulmonary artery myocytes.","Free radical biology &amp; medicine","2011 Apr 15","Korde AS, Yadav VR, Zheng YM, Wang YX"
< "Q8K2P6-1","18703841","X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus.","Acta crystallographica. Section D, Biological crystallography","2008 Sep","Levin EJ, Elsen NL, Seder KD, McCoy JG, Fox BG, Phillips GN Jr"
3633,3635c3950
< "Q9ET38-1","25678664","Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin.","Science (New York, N.Y.)","2015 Feb 13","Saitoh Y, Suzuki H, Tani K, Nishikawa K, Irie K, Ogura Y, Tamura A, Tsukita S, Fujiyoshi Y"
< "Q9ET38-1","15589828","Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells.","FEBS letters","2004 Dec 17","Luk JM, Tong MK, Mok BW, Tam PC, Yeung WS, Lee KF"
< "Q9Z0P7-1","29515120","Itch/beta-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.","Nature communications","2018 Mar 7","Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazza D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L"
---
> "Q9QY40-1","15218527","Plexin-B3 is a functional receptor for semaphorin 5A.","EMBO reports","2004 Jul","Artigiani S, Conrotto P, Fazzari P, Gilestro GF, Barberis D, Giordano S, Comoglio PM, Tamagnone L"
3637c3952
< "Q6PA06-1","27669642","Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology.","Experimental cell research","2016 Nov 15","Zhao G, Zhu PP, Renvoise B, Maldonado-Baez L, Park SH, Blackstone C"
---
> "Q60612-1","30365112","Amyloid beta and tau are involved in sleep disorder in Alzheimer's disease by orexin A and adenosine A(1) receptor.","International journal of molecular medicine","2019 Jan","Liu Z, Wang F, Tang M, Zhao Y, Wang X"
3649a3965,3969
> "B2RUR8-1","28880268","Cezanne predicts progression and adjuvant TACE response in hepatocellular carcinoma.","Cell death &amp; disease","2017 Sep 7","Wang JH, Zhong XP, Zhang YF, Wu XL, Li SH, Jian PE, Ling YH, Shi M, Chen MS, Wei W, Guo RP"
> "B2RUR8-1","28489822","TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.","Nature","2017 May 18","Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W"
> "P63158-1","30581279","Epac1 deacetylates HMGB1 through increased IGFBP-3 and SIRT1 levels in the retinal vasculature.","Molecular vision","2018","Jiang Y, Liu L, Steinle JJ"
> "Q6P1H6-1","25343476","Zinc finger protein Zfp335 is required for the formation of the naive T cell compartment.","eLife","2014 Oct 24","Han BY, Wu S, Foo CS, Horton RM, Jenne CN, Watson SR, Whittle B, Goodnow CC, Cyster JG"
> "Q99JY9-1","27927957","The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2016 Dec 7","Gokhale A, Hartwig C, Freeman AH, Das R, Zlatic SA, Vistein R, Burch A, Carrot G, Lewis AF, Nelms S, Dickman DK, Puthenveedu MA, Cox DN, Faundez V"
3653,3655c3973,3975
< "Q3U9N9-1","24248460","Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency.","Endocrinology","2014 Jan","Muller J, Mayerl S, Visser TJ, Darras VM, Boelen A, Frappart L, Mariotta L, Verrey F, Heuer H"
< "Q3U9N9-1","17273864","Recycling of aromatic amino acids via TAT1 allows efflux of neutral amino acids via LAT2-4F2hc exchanger.","Pflugers Archiv : European journal of physiology","2007 Jun","Ramadan T, Camargo SM, Herzog B, Bordin M, Pos KM, Verrey F"
< "Q3U9N9-1","16245314","Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway.","Journal of cellular physiology","2006 Mar","Ramadan T, Camargo SM, Summa V, Hunziker P, Chesnov S, Pos KM, Verrey F"
---
> "Q8CG19-1","27956181","Latent TGF-beta binding protein-1 deficiency decreases female fertility.","Biochemical and biophysical research communications","2017 Jan 22","Dietzel E, Weiskirchen S, Floehr J, Horiguchi M, Todorovic V, Rifkin DB, Jahnen-Dechent W, Weiskirchen R"
> "Q8CG19-1","25805620","Abrogation of both short and long forms of latent transforming growth factor-beta binding protein-1 causes defective cardiovascular development and is perinatally lethal.","Matrix biology : journal of the International Society for Matrix Biology","2015 Apr","Horiguchi M, Todorovic V, Hadjiolova K, Weiskirchen R, Rifkin DB"
> "O54826-1","30102091","MLLT10 promotes tumor migration, invasion, and metastasis in human colorectal cancer.","Scandinavian journal of gastroenterology","2018 Aug","Jing X, Wu H, Cheng X, Chen X, Zhang Y, Shi M, Zhang T, Wang X, Zhao R"
3657a3978
> "P54846-1","30713422","Rescue of cone function in cone-only Nphp5 knockout mouse model with Leber congenital amaurosis phenotype.","Molecular vision","2018","Hanke-Gogokhia C, Chiodo VA, Hauswirth WW, Frederick JM, Baehr W"
3659a3981,3986
> "Q9D6Y7-1","29649787","Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription.","Redox biology","2018 Jun","Pennington SM, Klutho PR, Xie L, Broadhurst K, Koval OM, McCormick ML, Spitz DR, Grumbach IM"
> "Q9D6Y7-1","29929200","Methionine Sulfoxide Reductase A Knockout Mice Show Progressive Hearing Loss and Sensitivity to Acoustic Trauma.","Audiology &amp; neuro-otology","2018","Alqudah S, Chertoff M, Durham D, Moskovitz J, Staecker H, Peppi M"
> "Q9D6Y7-1","28803836","Methionine sulfoxide reductase A protects against lipopolysaccharide-induced septic shock via negative regulation of the proinflammatory responses.","Archives of biochemistry and biophysics","2017 Oct 1","Singh MP, Kim KY, Kwak GH, Baek SH, Kim HY"
> "Q9D6Y7-1","28442342","Methionine sulfoxide reductase A protects hepatocytes against acetaminophen-induced toxicity via regulation of thioredoxin reductase 1 expression.","Biochemical and biophysical research communications","2017 Jun 3","Singh MP, Kwak GH, Kim KY, Kim HY"
> "Q9D6Y7-1","15924425","Role of structural and functional elements of mouse methionine-S-sulfoxide reductase in its subcellular distribution.","Biochemistry","2005 Jun 7","Kim HY, Gladyshev VN"
> "Q9D6Y7-1","12792026","Selenium-deficient diet enhances protein oxidation and affects methionine sulfoxide reductase (MsrB) protein level in certain mouse tissues.","Proceedings of the National Academy of Sciences of the United States of America","2003 Jun 24","Moskovitz J, Stadtman ER"
3665d3991
< "O55176-3","28067271","Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38alpha activation.","Nature communications","2017 Jan 9","Consalvi S, Brancaccio A, Dall'Agnese A, Puri PL, Palacios D"
3668,3672c3994
< "Q8BSP2-1","27737961","Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability.","Genes &amp; development","2016 Oct 1","Woodward J, Taylor GC, Soares DC, Boyle S, Sie D, Read D, Chathoth K, Vukovic M, Tarrats N, Jamieson D, Campbell KJ, Blyth K, Acosta JC, Ylstra B, Arends MJ, Kranc KR, Jackson AP, Bickmore WA, Wood AJ"
< "Q8BSP2-1","25961503","Condensin confers the longitudinal rigidity of chromosomes.","Nature cell biology","2015 Jun","Houlard M, Godwin J, Metson J, Lee J, Hirano T, Nasmyth K"
< "Q8BSP2-1","25474630","Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.","PLoS genetics","2014 Dec","Nishide K, Hirano T"
< "Q8BSP2-1","22333158","Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1.","The FEBS journal","2012 Apr","Theodoratos A, Wilson LO, Gosling KM, Fahrer AM"
< "Q8BSP2-1","17640884","A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development.","Proceedings of the National Academy of Sciences of the United States of America","2007 Jul 24","Gosling KM, Makaroff LE, Theodoratos A, Kim YH, Whittle B, Rui L, Wu H, Hong NA, Kennedy GC, Fritz JA, Yates AL, Goodnow CC, Fahrer AM"
---
> "Q91V45-1","14573733","The GPR54 gene as a regulator of puberty.","The New England journal of medicine","2003 Oct 23","Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno JS Jr, Shagoury JK, Bo-Abbas Y, Kuohung W, Schwinof KM, Hendrick AG, Zahn D, Dixon J, Kaiser UB, Slaugenhaupt SA, Gusella JF, O'Rahilly S, Carlton MB, Crowley WF Jr, Aparicio SA, Colledge WH"
3679d4000
< "Q9JJT2-1","16497798","Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice.","Endocrinology","2006 May","Lindfors PH, Lindahl M, Rossi J, Saarma M, Airaksinen MS"
3683,3684c4004,4006
< "Q80VW5-1","28966015","Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem.","Structure (London, England : 1993)","2017 Nov 7","Delhommel F, Cordier F, Bardiaux B, Bouvier G, Colcombet-Cazenave B, Brier S, Raynal B, Nouaille S, Bahloul A, Chamot-Rooke J, Nilges M, Petit C, Wolff N"
< "Q80VW5-1","28387217","Defective Gpsm2/Galphai3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.","Nature communications","2017 Apr 7","Mauriac SA, Hien YE, Bird JE, Carvalho SD, Peyroutou R, Lee SC, Moreau MM, Blanc JM, Geyser A, Medina C, Thoumine O, Beer-Hammer S, Friedman TB, Ruttiger L, Forge A, Nurnberg B, Sans N, Montcouquiol M"
---
> "Q2MH31-1","19213785","Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development.","The European respiratory journal","2009 May","Haitchi HM, Yoshisue H, Ribbene A, Wilson SJ, Holloway JW, Bucchieri F, Hanley NA, Wilson DI, Zummo G, Holgate ST, Davies DE"
> "Q2MH31-1","18163442","Isolation and characterization of the spermatid-specific Smrp1 gene encoding a novel manchette protein.","Molecular reproduction and development","2008 Jun","Matsuoka Y, Miyagawa Y, Tokuhiro K, Kitamura K, Iguchi N, Maekawa M, Takahashi T, Tsujimura A, Matsumiya K, Okuyama A, Nishimune Y, Tanaka H"
> "Q2MH31-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
3685a4008
> "Q99PI4-1","17158099","Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.","The Journal of biological chemistry","2007 Feb 9","Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K"
3695,3698d4017
< "Q9Z1G4-1","27512951","Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy.","Cell death &amp; disease","2016 Aug 11","Gao Y, Liu Y, Hong L, Yang Z, Cai X, Chen X, Fu Y, Lin Y, Wen W, Li S, Liu X, Huang H, Vogt A, Liu P, Yin XM, Li M"
< "Q9Z1G4-1","26427489","Modulation of V-ATPase by betaA3/A1-Crystallin in Retinal Pigment Epithelial Cells.","Advances in experimental medicine and biology","2016","Valapala M, Sergeev Y, Wawrousek E, Hose S, Zigler JS Jr, Sinha D"
< "Q9Z1G4-1","24468901","Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/betaA3/A1-crystallin via V-ATPase-MTORC1 signaling.","Autophagy","2014 Mar","Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler JS Jr, Sinha D"
< "Q9Z1G4-1","24165939","The V-ATPase membrane domain is a sensor of granular pH that controls the exocytotic machinery.","The Journal of cell biology","2013 Oct 28","Poea-Guyon S, Ammar MR, Erard M, Amar M, Moreau AW, Fossier P, Gleize V, Vitale N, Morel N"
3700,3701c4019
< "P97367-1","30190278","Variant PRC1 competes with retinoic acid-related signals to repress Meis2 in the mouse distal forelimb bud.","Development (Cambridge, England)","2018 Oct 11","Yakushiji-Kaminatsui N, Kondo T, Hironaka KI, Sharif J, Endo TA, Nakayama M, Masui O, Koseki Y, Kondo K, Ohara O, Vidal M, Morishita Y, Koseki H"
< "P97367-1","29641989","Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors.","Stem cell reports","2018 Apr 10","Kolb J, Anders-Maurer M, Muller T, Hau AC, Grebbin BM, Kallenborn-Gerhardt W, Behrends C, Schulte D"
---
> "Q7TPW1-1","24866383","NEXN inhibits GATA4 and leads to atrial septal defects in mice and humans.","Cardiovascular research","2014 Jul 15","Yang F, Zhou L, Wang Q, You X, Li Y, Zhao Y, Han X, Chang Z, He X, Cheng C, Wu C, Wang WJ, Hu FY, Zhao T, Li Y, Zhao M, Zheng GY, Dong J, Fan C, Yang J, Meng X, Zhang Y, Zhu X, Xiong J, Tian XL, Cao H"
3706a4025,4027
> "Q9WTJ6-1","14648882","Tesmin transcription is regulated differently during male and female meiosis.","Molecular reproduction and development","2004 Jan","Olesen C, Moller M, Byskov AG"
> "Q9WTJ6-1","12606435","Native tesmin is a 60-kilodalton protein that undergoes dynamic changes in its localization during spermatogenesis in mice.","Biology of reproduction","2003 May","Sutou S, Miwa K, Matsuura T, Kawasaki Y, Ohinata Y, Mitsui Y"
> "Q9WTJ6-1","11803038","Germ cell-specific nucleocytoplasmic shuttling protein, tesmin, responsive to heavy metal stress in mouse testes.","Journal of inorganic biochemistry","2002 Jan 15","Matsuura T, Kawasaki Y, Miwa K, Sutou S, Ohinata Y, Yoshida F, Mitsui Y"
3715,3717d4035
< "Q9JI57-1","29320702","Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.","Cell metabolism","2018 Jan 9","Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S"
< "Q9JI57-1","27295951","RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome.","BMC genomics","2016 Jun 13","Corley SM, Canales CP, Carmona-Mora P, Mendoza-Reinosa V, Beverdam A, Hardeman EC, Wilkins MR, Palmer SJ"
< "Q9JI57-1","27239038","An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter.","Cell reports","2016 Jun 7","Huo Y, Su T, Cai Q, Macara IG"
3718a4037,4040
> "P15806-1","30659202","E47 modulates hepatic glucocorticoid action.","Nature communications","2019 Jan 18","Hemmer MC, Wierer M, Schachtrup K, Downes M, Hubner N, Evans RM, Uhlenhaut NH"
> "P15806-1","29966657","Upregulation of lncRNA VDR/CASC15 induced by facilitates cardiac hypertrophy through modulating miR-432-5p/TLR4 axis.","Biochemical and biophysical research communications","2018 Sep 18","Li C, Zhou G, Feng J, Zhang J, Hou L, Cheng Z"
> "P15806-1","29703840","Transcription factor ID2 prevents E proteins from enforcing a naive T lymphocyte gene program during NK cell development.","Science immunology","2018 Apr 27","Zook EC, Li ZY, Xu Y, de Pooter RF, Verykokakis M, Beaulieu A, Lasorella A, Maienschein-Cline M, Sun JC, Sigvardsson M, Kee BL"
> "P15806-1","29440362","Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8(+) T cells.","The Journal of experimental medicine","2018 Mar 5","Omilusik KD, Nadjsombati MS, Shaw LA, Yu B, Milner JJ, Goldrath AW"
3720a4043
> "Q9WUZ9-1","21074248","The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway.","Cell","2010 Nov 24","Fang M, Shen Z, Huang S, Zhao L, Chen S, Mak TW, Wang X"
3723d4045
< "Q60520-2","29494759","Transcriptional co-repressor SIN3A silencing rescues decline in memory consolidation during scopolamine-induced amnesia.","Journal of neurochemistry","2018 May","Srivas S, Thakur MK"
3730d4051
< "O08644-1","28262839","Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.","Scientific reports","2017 Mar 6","Mateo-Lozano S, Bazzocco S, Rodrigues P, Mazzolini R, Andretta E, Dopeso H, Fernandez Y, Del Llano E, Bilic J, Suarez-Lopez L, Macaya I, Carton-Garcia F, Nieto R, Jimenez-Flores LM, de Marcondes PG, Nunez Y, Afonso E, Cacci K, Hernandez-Losa J, Landolfi S, Abasolo I, Ramon Y Cajal S, Mariadason JM, Schwartz S Jr, Matsui T, Arango D"
3731a4053,4064
> "Q80U23-1","28891816","Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer.","The Journal of clinical investigation","2017 Oct 2","Caino MC, Seo JH, Wang Y, Rivadeneira DB, Gabrilovich DI, Kim ET, Weeraratna AT, Languino LR, Altieri DC"
> "Q80U23-1","28472658","Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions.","Neuron","2017 May 3","Lin MY, Cheng XT, Tammineni P, Xie Y, Zhou B, Cai Q, Sheng ZH"
> "Q80U23-1","27370822","Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring.","Molecular brain","2016 Jul 2","Park C, Lee SA, Hong JH, Suh Y, Park SJ, Suh BK, Woo Y, Choi J, Huh JW, Kim YM, Park SK"
> "Q80U23-1","25834054","Deletion of mitochondrial anchoring protects dysmyelinating shiverer: implications for progressive MS.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Apr 1","Joshi DC, Zhang CL, Lin TM, Gusain A, Harris MG, Tree E, Yin Y, Wu C, Sheng ZH, Dempsey RJ, Fabry Z, Chiu SY"
> "Q80U23-1","23857772","Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport.","The Journal of cell biology","2013 Jul 22","Chen Y, Sheng ZH"
> "Q80U23-1","19641106","Dynein light chain LC8 regulates syntaphilin-mediated mitochondrial docking in axons.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2009 Jul 29","Chen YM, Gerwin C, Sheng ZH"
> "Q80U23-1","18191227","Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.","Cell","2008 Jan 11","Kang JS, Tian JH, Pan PY, Zald P, Li C, Deng C, Sheng ZH"
> "Q9Z2G9-1","25530119","TIP30 inhibits oligodendrocyte precursor cell differentiation via cytoplasmic sequestration of Olig1.","Glia","2015 Apr","Yang W, Xiao L, Li C, Liu X, Liu M, Shao Q, Wang D, Huang A, He C"
> "Q9Z2G9-1","25175814","Proteomic analysis of livers from fat-fed mice deficient in either PKCdelta or PKCepsilon identifies Htatip2 as a regulator of lipid metabolism.","Proteomics","2014 Nov","Liao BM, Raddatz K, Zhong L, Parker BL, Raftery MJ, Schmitz-Peiffer C"
> "Q9Z2G9-1","24853420","Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression.","Cell death &amp; disease","2014 May 22","Chen F, Li A, Gao S, Hollern D, Williams M, Liu F, VanSickle EA, Andrechek E, Zhang C, Yang C, Luo R, Xiao H"
> "Q9Z2G9-1","22733137","TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice.","Oncogene","2013 May 2","Li A, Zhang C, Gao S, Chen F, Yang C, Luo R, Xiao H"
> "Q9Z2G9-1","21252234","A novel TIP30 protein complex regulates EGF receptor signaling and endocytic degradation.","The Journal of biological chemistry","2011 Mar 18","Zhang C, Li A, Zhang X, Xiao H"
3736a4070
> "P12032-1","30572657","The Activity of Matrix Metalloproteinases (MMP-2, MMP-9) and Their Tissue Inhibitors (TIMP-1, TIMP-3) in the Cerebral Cortex and Hippocampus in Experimental Acanthamoebiasis.","International journal of molecular sciences","2018 Dec 19","Lanocha-Arendarczyk N, Baranowska-Bosiacka I, Gutowska I, Kolasa-Wolosiuk A, Kot K, Lanocha A, Metryka E, Wiszniewska B, Chlubek D, Kosik-Bogacka D"
3742,3744c4076,4077
< "Q80U62-1","30783089","Suppression of autophagic activity by Rubicon is a signature of aging.","Nature communications","2019 Feb 19","Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T"
< "Q80U62-1","19270696","Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.","Nature cell biology","2009 Apr","Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T, Akira S, Noda T, Yoshimori T"
< "Q80U62-1","19270693","Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.","Nature cell biology","2009 Apr","Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z"
---
> "Q99MU3-1","30669342","ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis.","International journal of molecular sciences","2019 Jan 18","Zhang X, Gao X, Hu J, Xie Y, Zuo Y, Xu H, Zhu S"
> "Q99MU3-1","28960389","The Other Face of an Editor: ADAR1 Functions in Editing-Independent Ways.","BioEssays : news and reviews in molecular, cellular and developmental biology","2017 Nov","Licht K, Jantsch MF"
3746d4078
< "Q80TL4-1","27145804","Peripheral nerve injury induces loss of nociceptive neuron-specific Galphai-interacting protein in neuropathic pain rat.","Molecular pain","2016","Liu Z, Wang F, Fischer G, Hogan QH, Yu H"
3752d4083
< "Q9JLC6-1","30515906","Thyrotroph embryonic factor is downregulated in bladder cancer and suppresses proliferation and tumorigenesis via the AKT/FOXOs signalling pathway.","Cell proliferation","2019 Mar","Yang J, Wang B, Chen H, Chen X, Li J, Chen Y, Yuan D, Zheng S"
3761,3764d4091
< "Q9JJ57-1","20678225","Roles of KChIP1 in the regulation of GABA-mediated transmission and behavioral anxiety.","Molecular brain","2010 Aug 2","Xia K, Xiong H, Shin Y, Wang D, Deerinck T, Takahashi H, Ellisman MH, Lipton SA, Tong G, Descalzi G, Zhang D, Zhuo M, Zhang Z"
< "Q9JJ57-1","17640927","The aromatic cluster in KCHIP1b affects Kv4 inactivation gating.","The Journal of physiology","2007 Sep 15","Van Hoorick D, Raes A, Snyders DJ"
< "Q9JJ57-1","15363885","Differential distribution of KChIPs mRNAs in adult mouse brain.","Brain research. Molecular brain research","2004 Sep 28","Xiong H, Kovacs I, Zhang Z"
< "Q9JJ57-1","14572458","Differential modulation of Kv4 kinetics by KCHIP1 splice variants.","Molecular and cellular neurosciences","2003 Oct","Van Hoorick D, Raes A, Keysers W, Mayeur E, Snyders DJ"
3770,3771d4096
< "Q9D842-1","27875275","Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.","Journal of cell science","2016 Dec 15","Syed KM, Joseph S, Mukherjee A, Majumder A, Teixeira JM, Dutta D, Pillai MR"
< "Q9D842-1","21211721","PARP-3 and APLF function together to accelerate nonhomologous end-joining.","Molecular cell","2011 Jan 7","Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW"
3782a4108,4110
> "Q9QXS1-1","18541706","Plectin isoform 1b mediates mitochondrion-intermediate filament network linkage and controls organelle shape.","The Journal of cell biology","2008 Jun 16","Winter L, Abrahamsberg C, Wiche G"
> "Q9QXS1-1","17389230","Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.","The Journal of cell biology","2007 Mar 26","Rezniczek GA, Konieczny P, Nikolic B, Reipert S, Schneller D, Abrahamsberg C, Davies KE, Winder SJ, Wiche G"
> "Q9QXS1-1","12542521","Plectin-isoform-specific rescue of hemidesmosomal defects in plectin (-/-) keratinocytes.","The Journal of investigative dermatology","2003 Feb","Andra K, Kornacker I, Jorgl A, Zorer M, Spazierer D, Fuchs P, Fischer I, Wiche G"
3795a4124
> "Q8C5Q4-1","25184340","Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment.","PloS one","2014","Nieradka A, Ufer C, Thiadens K, Grech G, Horos R, van Coevorden-Hameete M, van den Akker E, Sofi S, Kuhn H, von Lindern M"
3798,3802d4126
< "Q5U4C1-1","25657005","Alternative binding modes identified for growth and differentiation factor-associated serum protein (GASP) family antagonism of myostatin.","The Journal of biological chemistry","2015 Mar 20","Walker RG, Angerman EB, Kattamuri C, Lee YS, Lee SJ, Thompson TB"
< "Q5U4C1-1","25277978","Absence of hyperplasia in Gasp-1 overexpressing mice is dependent on myostatin up-regulation.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2014","Brun C, Perie L, Baraige F, Vernus B, Bonnieu A, Blanquet V"
< "Q5U4C1-1","24019467","Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.","Proceedings of the National Academy of Sciences of the United States of America","2013 Sep 24","Lee YS, Lee SJ"
< "Q5U4C1-1","23046573","Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype.","BMC genomics","2012 Oct 10","Monestier O, Brun C, Heu K, Passet B, Malhouroux M, Magnol L, Vilotte JL, Blanquet V"
< "Q5U4C1-1","21091868","Impaired striatum-dependent behavior in GASP-1-knock-out mice.","Genes, brain, and behavior","2011 Apr","Mathis C, Bott JB, Candusso MP, Simonin F, Cassel JC"
3804a4129,4132
> "Q80XU8-1","18585462","Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth.","Molecular and cellular neurosciences","2008 Sep","Wang PY, Seabold GK, Wenthold RJ"
> "Q9QXJ1-1","27734846","FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation.","Scientific reports","2016 May 11","Strecker P, Ludewig S, Rust M, Mundinger TA, Gorlich A, Krachan EG, Mehrfeld C, Herz J, Korte M, Guenette SY, Kins S"
> "Q9QXJ1-1","26276215","Fe65 negatively regulates Jagged1 signaling by decreasing Jagged1 protein stability through the E3 ligase Neuralized-like 1.","Biochimica et biophysica acta","2015 Nov","Lee HJ, Yoon JH, Ahn JS, Jo EH, Kim MY, Lee YC, Kim JW, Ann EJ, Park HS"
> "Q9QXJ1-1","25757569","FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2015 Jun","Suh J, Moncaster JA, Wang L, Hafeez I, Herz J, Tanzi RE, Goldstein LE, Guenette SY"
3807a4136
> "Q8VCD6-1","20943918","REEP2 enhances sweet receptor function by recruitment to lipid rafts.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2010 Oct 13","Ilegems E, Iwatsuki K, Kokrashvili Z, Benard O, Ninomiya Y, Margolskee RF"
3816,3817d4144
< "Q3UNX5-1","25744306","High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the adipose tissue, along with increased expression of extracellular matrix remodelling- and inflammation-related genes.","The British journal of nutrition","2015 Mar 28","Choi MS, Kim YJ, Kwon EY, Ryoo JY, Kim SR, Jung UJ"
< "Q3UNX5-1","12707288","Analysis of the role of the SA gene in blood pressure regulation by gene targeting.","Hypertension (Dallas, Tex. : 1979)","2003 Jun","Walsh V, Somody L, Farrell A, Zhang B, Brown J, Pritchard C, Vincent M, Samani NJ"
3820,3823d4146
< "Q9D5T7-1","29414051","Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1.","DNA repair","2018 Mar","Carofiglio F, Sleddens-Linkels E, Wassenaar E, Inagaki A, van Cappellen WA, Grootegoed JA, Toth A, Baarends WM"
< "Q9D5T7-1","19686734","A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes.","Experimental cell research","2010 Jan 15","Fukuda T, Daniel K, Wojtasz L, Toth A, Hoog C"
< "Q9D5T7-1","19851446","Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase.","PLoS genetics","2009 Oct","Wojtasz L, Daniel K, Roig I, Bolcun-Filas E, Xu H, Boonsanay V, Eckmann CR, Cooke HJ, Jasin M, Keeney S, McKay MJ, Toth A"
< "Q9D5T7-1","15567723","Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain-containing protein.","Gene expression patterns : GEP","2004 Dec","Pangas SA, Yan W, Matzuk MM, Rajkovic A"
3833d4155
< "Q2WF71-1","18585462","Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth.","Molecular and cellular neurosciences","2008 Sep","Wang PY, Seabold GK, Wenthold RJ"
3838a4161,4164
> "Q3UN02-1","28751023","Lysocardiolipin acyltransferase regulates TGF-beta mediated lung fibroblast differentiation.","Free radical biology &amp; medicine","2017 Nov","Huang LS, Jiang P, Feghali-Bostwick C, Reddy SP, Garcia JGN, Natarajan V"
> "Q3UN02-1","24779708","The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.","American journal of respiratory and critical care medicine","2014 Jun 1","Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan V"
> "Q3UN02-1","19372376","Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.","Proceedings of the National Academy of Sciences of the United States of America","2009 May 5","Calvo SE, Pagliarini DJ, Mootha VK"
> "Q3UN02-1","15152008","A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse.","The Journal of biological chemistry","2004 Jul 23","Cao J, Liu Y, Lockwood J, Burn P, Shi Y"
3844a4171
> "Q3TL44-1","30191480","The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1.","Molecular and cellular biochemistry","2019 Mar","Killackey SA, Rahman MA, Soares F, Zhang AB, Abdel-Nour M, Philpott DJ, Girardin SE"
3846a4174
> "P70362-1","26112410","The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-kappaB Signaling via Partial Degradation of the NF-kappaB Subunit p100.","The Journal of biological chemistry","2015 Aug 7","Zhang Z, Wang Y, Li C, Shi Z, Hao Q, Wang W, Song X, Zhao Y, Jiao S, Zhou Z"
3849a4178
> "P60904-1","28424476","Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo.","Scientific reports","2017 Apr 19","Deng J, Koutras C, Donnelier J, Alshehri M, Fotouhi M, Girard M, Casha S, McPherson PS, Robbins SM, Braun JEA"
3855c4184,4187
< "O08575-1","30628662","Eya2 is critical for the E2AHLFmediated immortalization of mouse hematopoietic stem/progenitor cells.","International journal of oncology","2019 Mar","Maharjan BD, Ono R, Nosaka T"
---
> "Q9DBS9-1","17303778","Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis.","Arteriosclerosis, thrombosis, and vascular biology","2007 May","Yan D, Lehto M, Rasilainen L, Metso J, Ehnholm C, Yla-Herttuala S, Jauhiainen M, Olkkonen VM"
> "Q9CR75-1","12529173","The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.","The Biochemical journal","2003 Apr 15","Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA"
> "Q9D9X8-1","25038051","The role of SPRASA in female fertility.","Reproductive sciences (Thousand Oaks, Calif.)","2015 Apr","Wagner A, Holland OJ, Tong M, Shelling AN, Chamley LW"
> "Q9D9X8-1","22206759","Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization.","Developmental biology","2012 Mar 1","Sachdev M, Mandal A, Mulders S, Digilio LC, Panneerdoss S, Suryavathi V, Pires E, Klotz KL, Hermens L, Herrero MB, Flickinger CJ, van Duin M, Herr JC"
3862,3865c4194
< "Q8BND5-1","27581528","Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.","Free radical biology &amp; medicine","2016 Oct","Zhang L, Cheng Q, Zhang L, Wang Y, Merrill GF, Ilani T, Fass D, Arner ESJ, Zhang J"
< "Q8BND5-1","24475161","QSOX1 inhibits autophagic flux in breast cancer cells.","PloS one","2014","Poillet L, Pernodet N, Boyer-Guittaut M, Adami P, Borg C, Jouvenot M, Delage-Mourroux R, Despouy G"
< "Q8BND5-1","16160860","Cell-specific localization of the sulphydryl oxidase QSOX in rat peripheral tissues.","Cell and tissue research","2006 Jan","Tury A, Mairet-Coello G, Esnard-Feve A, Benayoun B, Risold PY, Griffond B, Fellmann D"
< "Q8BND5-1","12354420","Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells.","Journal of dermatological science","2002 Oct","Matsuba S, Suga Y, Ishidoh K, Hashimoto Y, Takamori K, Kominami E, Wilhelm B, Seitz J, Ogawa H"
---
> "P70663-1","29084211","SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/beta-catenin signaling through stabilization of the WNT-receptor complex.","Oncogene","2018 Feb 22","Zhao SJ, Jiang YQ, Xu NW, Li Q, Zhang Q, Wang SY, Li J, Wang YH, Zhang YL, Jiang SH, Wang YJ, Huang YJ, Zhang XX, Tian GA, Zhang CC, Lv YY, Dai M, Liu F, Zhang R, Zhou D, Zhang ZG"
3866a4196
> "P21126-1","25713138","Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis.","The Journal of biological chemistry","2015 Apr 10","Kuwabara N, Minami R, Yokota N, Matsumoto H, Senda T, Kawahara H, Kato R"
3868a4199
> "Q9CQ20-1","18556348","Hepatic expression of the SPOT 14 (S14) paralog S14-related (Mid1 interacting protein) is regulated by dietary carbohydrate.","Endocrinology","2008 Oct","Tsatsos NG, Augustin LB, Anderson GW, Towle HC, Mariash CN"
3886,3890d4216
< "Q8K2F0-1","28733670","BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.","Scientific reports","2017 Jul 21","Roberts TC, Etxaniz U, Dall'Agnese A, Wu SY, Chiang CM, Brennan PE, Wood MJA, Puri PL"
< "Q8K2F0-1","27667451","[Brd3 promotes IL-6 production via enhancing acetylase CBP recruitment and histone 3 acetylation within IL6 promoter].","Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology","2016 Oct","Ren W, Sun D, Wang C, Li N"
< "Q8K2F0-1","24248598","Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.","Molecular and cellular biology","2014 Feb","Wienerroither S, Rauch I, Rosebrock F, Jamieson AM, Bradner J, Muhar M, Zuber J, Muller M, Decker T"
< "Q8K2F0-1","16008511","Differentially expressed genes in endothelial differentiation.","DNA and cell biology","2005 Jul","Ishii H, Mimori K, Mori M, Vecchione A"
< "Q8K2F0-1","15128596","Pre-sertoli specific gene expression profiling reveals differential expression of Ppt1 and Brd3 genes within the mouse genital ridge at the time of sex determination.","Biology of reproduction","2004 Sep","Boyer A, Lussier JG, Sinclair AH, McClive PJ, Silversides DW"
3893,3894c4219,4220
< "Q8R4V2-1","27891578","Dual specificity phosphatase 15 regulates Erk activation in Schwann cells.","Journal of neurochemistry","2017 Feb","Rodriguez-Molina JF, Lopez-Anido C, Ma KH, Zhang C, Olson T, Muth KN, Weider M, Svaren J"
< "Q8R4V2-1","15138252","VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.","The Journal of biological chemistry","2004 Jul 30","Alonso A, Narisawa S, Bogetz J, Tautz L, Hadzic R, Huynh H, Williams S, Gjorloff-Wingren A, Bremer MC, Holsinger LJ, Millan JL, Mustelin T"
---
> "Q9QYB5-1","22706708","gamma-Adducin promotes process outgrowth and secretory protein exit from the Golgi apparatus.","Journal of molecular neuroscience : MN","2013 Jan","Lou H, Park JJ, Phillips A, Loh YP"
> "Q9QYB5-1","19900187","beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits.","Genes, brain, and behavior","2010 Feb","Porro F, Rosato-Siri M, Leone E, Costessi L, Iaconcig A, Tongiorgi E, Muro AF"
3896a4223
> "P61215-1","28154140","Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.","Proceedings of the National Academy of Sciences of the United States of America","2017 Feb 14","Sterky FH, Trotter JH, Lee SJ, Recktenwald CV, Du X, Zhou B, Zhou P, Schwenk J, Fakler B, Sudhof TC"
3899,3902d4225
< "Q69ZP3-1","25730884","Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis.","Proceedings of the National Academy of Sciences of the United States of America","2015 Mar 10","Shen Y, Ge WP, Li Y, Hirano A, Lee HY, Rohlmann A, Missler M, Tsien RW, Jan LY, Fu YH, Ptacek LJ"
< "Q69ZP3-1","22214848","Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia.","The Journal of clinical investigation","2012 Feb","Lee HY, Nakayama J, Xu Y, Fan X, Karouani M, Shen Y, Pothos EN, Hess EJ, Fu YH, Edwards RH, Ptacek LJ"
< "Q69ZP3-1","20040360","Silencing MR-1 attenuates inflammatory damage in mice heart induced by AngII.","Biochemical and biophysical research communications","2010 Jan 15","Dai W, Chen H, Jiang J, Kong W, Wang Y"
< "Q69ZP3-1","15496428","The gene for paroxysmal non-kinesigenic dyskinesia encodes an enzyme in a stress response pathway.","Human molecular genetics","2004 Dec 15","Lee HY, Xu Y, Huang Y, Ahn AH, Auburger GW, Pandolfo M, Kwiecinski H, Grimes DA, Lang AE, Nielsen JE, Averyanov Y, Servidei S, Friedman A, Van Bogaert P, Abramowicz MJ, Bruno MK, Sorensen BF, Tang L, Fu YH, Ptacek LJ"
3906a4230,4234
> "P28574-1","30403691","DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.","PloS one","2018","Tatsumi D, Hayashi Y, Endo M, Kobayashi H, Yoshioka T, Kiso K, Kanno S, Nakai Y, Maeda I, Mochizuki K, Tachibana M, Koseki H, Okuda A, Yasui A, Kono T, Matsui Y"
> "P28574-1","28220481","Does MAX open up a new avenue for meiotic research?","Development, growth &amp; differentiation","2017 Feb","Suzuki A, Hirasaki M, Okuda A"
> "P28574-1","27025988","Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells.","Nature communications","2016 Mar 30","Suzuki A, Hirasaki M, Hishida T, Wu J, Okamura D, Ueda A, Nishimoto M, Nakachi Y, Mizuno Y, Okazaki Y, Matsui Y, Izpisua Belmonte JC, Okuda A"
> "Q8K0H7-1","25164149","Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae.","The Biochemical journal","2014 Dec 1","Bartolke R, Heinisch JJ, Wieczorek H, Vitavska O"
> "Q8K0H7-1","22521588","miR-32 and its target SLC45A3 regulate the lipid metabolism of oligodendrocytes and myelin.","Neuroscience","2012 Jun 28","Shin D, Howng SY, Ptacek LJ, Fu YH"
3907a4236,4237
> "Q69ZX6-1","29728365","A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.","Genome research","2018 Jun","Fukuda K, Okuda A, Yusa K, Shinkai Y"
> "Q69ZX6-1","24286864","Cytosolic functions of MORC2 in lipogenesis and adipogenesis.","Biochimica et biophysica acta","2014 Feb","Sanchez-Solana B, Li DQ, Kumar R"
3912,3913d4241
< "Q3UPF5-1","23776219","Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform.","Proceedings of the National Academy of Sciences of the United States of America","2013 Jul 2","Charron G, Li MM, MacDonald MR, Hang HC"
< "Q3UPF5-1","22951821","Zinc finger antiviral protein inhibits murine gammaherpesvirus 68 M2 expression and regulates viral latency in cultured cells.","Journal of virology","2012 Nov","Xuan Y, Liu L, Shen S, Deng H, Gao G"
3914a4243,4244
> "Q8CCG4-1","29327467","ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells.","Stem cells (Dayton, Ohio)","2018 May","Somanath P, Bush KM, Knoepfler PS"
> "Q8CCG4-1","18366076","Identification of DPPA4 and other genes as putative Sox2:Oct-3/4 target genes using a combination of in silico analysis and transcription-based assays.","Journal of cellular physiology","2008 Sep","Chakravarthy H, Boer B, Desler M, Mallanna SK, McKeithan TW, Rizzino A"
3916a4247,4248
> "Q80U58-1","29046322","Pumilio2-deficient mice show a predisposition for epilepsy.","Disease models &amp; mechanisms","2017 Nov 1","Follwaczny P, Schieweck R, Riedemann T, Demleitner A, Straub T, Klemm AH, Bilban M, Sutor B, Popper B, Kiebler MA"
> "Q80U58-1","28794184","Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.","Genes &amp; development","2017 Jul 1","Zhang M, Chen D, Xia J, Han W, Cui X, Neuenkirchen N, Hermes G, Sestan N, Lin H"
3927a4260,4264
> "Q5U4C1-1","25657005","Alternative binding modes identified for growth and differentiation factor-associated serum protein (GASP) family antagonism of myostatin.","The Journal of biological chemistry","2015 Mar 20","Walker RG, Angerman EB, Kattamuri C, Lee YS, Lee SJ, Thompson TB"
> "Q5U4C1-1","25277978","Absence of hyperplasia in Gasp-1 overexpressing mice is dependent on myostatin up-regulation.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2014","Brun C, Perie L, Baraige F, Vernus B, Bonnieu A, Blanquet V"
> "Q5U4C1-1","24019467","Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.","Proceedings of the National Academy of Sciences of the United States of America","2013 Sep 24","Lee YS, Lee SJ"
> "Q5U4C1-1","23046573","Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype.","BMC genomics","2012 Oct 10","Monestier O, Brun C, Heu K, Passet B, Malhouroux M, Magnol L, Vilotte JL, Blanquet V"
> "Q5U4C1-1","21091868","Impaired striatum-dependent behavior in GASP-1-knock-out mice.","Genes, brain, and behavior","2011 Apr","Mathis C, Bott JB, Candusso MP, Simonin F, Cassel JC"
3932a4270,4274
> "Q8BMQ8-1","20305638","Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.","Nature","2010 Apr 1","Kinchen JM, Ravichandran KS"
> "P59438-1","27333462","Simple chronic colitis model using hypopigmented mice with a Hermansky-Pudlak syndrome 5 gene mutation.","Pigment cell &amp; melanoma research","2016 Sep","Itoh Y, Nagaoka Y, Katakura Y, Kawahara H, Takemori H"
> "P59438-1","23672590","The mouse ruby-eye 2(d) (ru2(d) /Hps5(ru2-d) ) allele inhibits eumelanin but not pheomelanin synthesis.","Pigment cell &amp; melanoma research","2013 Sep","Hirobe T, Ito S, Wakamatsu K"
> "P59438-1","23030338","A new mutation of mouse ruby-eye 2, ru2(d)/Hps5(ru2-d) inhibits eumelanin synthesis but stimulates pheomelanin synthesis in melanocytes.","Zoological science","2012 Oct","Hirobe T, Wakamatsu K, Ito S"
> "P59438-1","22035301","A novel deletion mutation of mouse ruby-eye 2 named ru2(d)/Hps5(ru2-d) inhibits melanocyte differentiation and its impaired differentiation is rescued by L-tyrosine.","Zoological science","2011 Nov","Hirobe T, Yoshihara C, Takeuchi S, Wakamatsu K, Ito S, Abe H, Kawa Y, Soma Y"
3943,3944d4284
< "P17095-2","29316384","HMGA1 Overexpression is Associated With the Malignant Status and Progression of Breast Cancer.","Anatomical record (Hoboken, N.J. : 2007)","2018 Jun","Qi C, Cao J, Li M, Liang C, He Y, Li Y, Li J, Zheng X, Wang L, Wei B"
< "P17095-2","29101051","Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1.","Biochimica et biophysica acta. Molecular basis of disease","2018 Feb","Xue W, Huang J, Chen H, Zhang Y, Zhu X, Li J, Zhang W, Yuan Y, Wang Y, Zheng L, Huang K"
3946c4286,4287
< "Q6PHZ2-1","28383548","miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2.","Cell death &amp; disease","2017 Apr 6","Zhang X, Wang C, Zhao J, Xu J, Geng Y, Dai L, Huang Y, Fu SC, Dai K, Zhang X"
---
> "Q80W68-1","29717104","Overexpression of Kin of IRRE-Like Protein 1 (KIRREL) in Gastric Cancer and Its Clinical Prognostic Significance.","Medical science monitor : international medical journal of experimental and clinical research","2018 May 2","Zhang MJ, Hong YY, Li N"
> "Q80W68-1","12538735","Alternatively used promoters and distinct elements direct tissue-specific expression of nephrin.","Journal of the American Society of Nephrology : JASN","2003 Feb","Beltcheva O, Kontusaari S, Fetissov S, Putaala H, Kilpelainen P, Hokfelt T, Tryggvason K"
3949a4291,4292
> "O35671-1","28049720","ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKalpha balance.","Journal of cell science","2017 Feb 1","Bouin AP, Kyumurkov A, Regent-Kloeckner M, Ribba AS, Faurobert E, Fournier HN, Bourrin-Reynard I, Manet-Dupe S, Oddou C, Balland M, Planus E, Albiges-Rizo C"
> "Q64143-1","29350678","PIK3R3 regulates PPARalpha expression to stimulate fatty acid beta-oxidation and decrease hepatosteatosis.","Experimental &amp; molecular medicine","2018 Jan 19","Yang X, Fu Y, Hu F, Luo X, Hu J, Wang G"
3950a4294,4297
> "Q91WT8-1","30309881","Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver.","RNA (New York, N.Y.)","2019 Jan","Blanc V, Xie Y, Kennedy S, Riordan JD, Rubin DC, Madison BB, Mills JC, Nadeau JH, Davidson NO"
> "Q91WT8-1","26789794","Conditional restoration and inactivation of Rbm47 reveal its tissue-context requirement for viability and growth.","Genesis (New York, N.Y. : 2000)","2016 Mar","Fossat N, Radziewic T, Jones V, Tourle K, Tam PP"
> "Q91WT8-1","24916387","C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.","EMBO reports","2014 Aug","Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert JB, Power M, Jones V, Loebel DA, Tam PP"
> "Q91WT8-1","23649762","RNA-binding protein Rbm47 binds to Nanog in mouse embryonic stem cells.","Molecular biology reports","2013 Jul","Yeganeh M, Seyedjafari E, Kamrani FA, Ghaemi N"
3955,3962d4301
< "Q8CAE2-1","29703750","Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain.","The Journal of biological chemistry","2018 Jun 29","Peng L, Zhang F, Shang R, Wang X, Chen J, Chou JJ, Ma J, Wu L, Huang Y"
< "Q8CAE2-1","26496356","HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.","PLoS genetics","2015 Oct","Lim SL, Qu ZP, Kortschak RD, Lawrence DM, Geoghegan J, Hempfling AL, Bergmann M, Goodnow CC, Ormandy CJ, Wong L, Mann J, Scott HS, Jamsai D, Adelson DL, O'Bryan MK"
< "Q2EG98-1","21185261","The single pore residue Asp523 in PKD2L1 determines Ca2+ permeation of the PKD1L3/PKD2L1 complex.","Biochemical and biophysical research communications","2011 Jan 28","Fujimoto C, Ishimaru Y, Katano Y, Misaka T, Yamasoba T, Asakura T, Abe K"
< "Q2EG98-1","19464260","Acetic acid activates PKD1L3-PKD2L1 channel--a candidate sour taste receptor.","Biochemical and biophysical research communications","2009 Jul 31","Ishii S, Misaka T, Kishi M, Kaga T, Ishimaru Y, Abe K"
< "Q2EG98-1","18535624","Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1.","EMBO reports","2008 Jul","Inada H, Kawabata F, Ishimaru Y, Fushiki T, Matsunami H, Tominaga M"
< "Q2EG98-1","16891422","Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor.","Proceedings of the National Academy of Sciences of the United States of America","2006 Aug 15","Ishimaru Y, Inada H, Kubota M, Zhuang H, Tominaga M, Matsunami H"
< "Q2EG98-1","16805797","Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.","Journal of neurochemistry","2006 Jul","LopezJimenez ND, Cavenagh MM, Sainz E, Cruz-Ithier MA, Battey JF, Sullivan SL"
< "Q2EG98-1","12782129","Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes.","Genomics","2003 Jun","Li A, Tian X, Sung SW, Somlo S"
3968,3970d4306
< "Q80U72-1","30083817","Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells.","Journal of cancer research and clinical oncology","2018 Oct","Dash BP, Schnoder TM, Kathner C, Mohr J, Weinert S, Herzog C, Godavarthy PS, Zanetti C, Perner F, Braun-Dullaeus R, Hartleben B, Huber TB, Walz G, Naumann M, Ellis S, Vasioukhin V, Kahne T, Krause DS, Heidel FH"
< "Q80U72-1","12499390","Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse.","Human molecular genetics","2003 Jan 15","Murdoch JN, Henderson DJ, Doudney K, Gaston-Massuet C, Phillips HM, Paternotte C, Arkell R, Stanier P, Copp AJ"
< "Q80U72-1","12112872","A new allele of Gli3 and a new mutation, circletail (Crc), resulting from a single transgenic experiment.","Genesis (New York, N.Y. : 2000)","2002 Jun","Rachel RA, Wellington SJ, Warburton D, Mason CA, Beermann F"
3979a4316,4317
> "Q9R0L1-1","27586257","Heat shock factor 4 regulates lens epithelial cell homeostasis by working with lysosome and anti-apoptosis pathways.","The international journal of biochemistry &amp; cell biology","2016 Oct","Cui X, Liu H, Li J, Guo K, Han W, Dong Y, Wan S, Wang X, Jia P, Li S, Ma Y, Zhang J, Mu H, Hu Y"
> "Q9R0L1-1","15483628","HSF4 is required for normal cell growth and differentiation during mouse lens development.","The EMBO journal","2004 Oct 27","Fujimoto M, Izu H, Seki K, Fukuda K, Nishida T, Yamada S, Kato K, Yonemura S, Inouye S, Nakai A"
3981c4319
< "Q9QUK0-1","14605869","Postnatal expression of Cdkl2 in mouse brain revealed by LacZ inserted into the Cdkl2 locus.","Cell and tissue research","2004 Feb","Sassa T, Gomi H, Itohara S"
---
> "Q8VEA6-1","14660436","A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.","Development (Cambridge, England)","2004 Jan","Nakayama N, Han CY, Cam L, Lee JI, Pretorius J, Fisher S, Rosenfeld R, Scully S, Nishinakamura R, Duryea D, Van G, Bolon B, Yokota T, Zhang K"
3984,3985c4322,4323
< "Q06219-1","30267803","Nurr1 exacerbates cerebral ischemia-reperfusion injury via modulating YAP-INF2-mitochondrial fission pathways.","The international journal of biochemistry &amp; cell biology","2018 Nov","Zhang Z, Yu J"
< "Q06219-1","30111648","Compensatory Expression of Nur77 and Nurr1 Regulates NF-kappaB-Dependent Inflammatory Signaling in Astrocytes.","Molecular pharmacology","2018 Oct","Popichak KA, Hammond SL, Moreno JA, Afzali MF, Backos DS, Slayden RD, Safe S, Tjalkens RB"
---
> "Q1XH17-1","30614598","Mitsugumin 53 promotes mitochondrial autophagy through regulating Ambra1 expression in C2C12 myoblast cells.","Cell biology international","2019 Mar","Lijie G, Yueyue Z, Nan Z, Ling W, Xuan W, Weijie Y"
> "Q1XH17-1","19380584","Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin.","The Journal of biological chemistry","2009 Jun 5","Cai C, Weisleder N, Ko JK, Komazaki S, Sunada Y, Nishi M, Takeshima H, Ma J"
3988,3993c4326,4329
< "O88838-1","28270450","Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.","Blood","2017 May 4","Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK"
< "O88838-1","20561531","Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.","Journal of molecular biology","2010 Aug 20","Filippakopoulos P, Low A, Sharpe TD, Uppenberg J, Yao S, Kuang Z, Savitsky P, Lewis RS, Nicholson SE, Norton RS, Bullock AN"
< "O88838-1","20603330","The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.","The Journal of cell biology","2010 Jul 12","Kuang Z, Lewis RS, Curtis JM, Zhan Y, Saunders BM, Babon JJ, Kolesnik TB, Low A, Masters SL, Willson TA, Kedzierski L, Yao S, Handman E, Norton RS, Nicholson SE"
< "O88838-1","17088318","Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.","Protein science : a publication of the Protein Society","2006 Dec","Yao S, Liu MS, Masters SL, Zhang JG, Babon JJ, Nicola NA, Nicholson SE, Norton RS"
< "O88838-1","16369487","The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.","Nature structural &amp; molecular biology","2006 Jan","Masters SL, Yao S, Willson TA, Zhang JG, Palmer KR, Smith BJ, Babon JJ, Nicola NA, Norton RS, Nicholson SE"
< "O88838-1","15964819","Genetic deletion of murine SPRY domain-containing SOCS box protein 2 (SSB-2) results in very mild thrombocytopenia.","Molecular and cellular biology","2005 Jul","Masters SL, Palmer KR, Stevenson WS, Metcalf D, Viney EM, Sprigg NS, Alexander WS, Nicola NA, Nicholson SE"
---
> "Q8CC88-1","29660410","The spatial and developmental expression of mouse Vwa8 (von Willebrand domain-containing protein 8).","Gene expression patterns : GEP","2018 Sep","Grewe BS, Richmond JE, Featherstone DE"
> "Q8CC88-1","28414126","Characterization of the novel protein KIAA0564 (Von Willebrand Domain-containing Protein 8).","Biochemical and biophysical research communications","2017 Jun 3","Luo M, Mengos AE, Ma W, Finlayson J, Bustos RZ, Xiao Zhu Y, Shi CX, Stubblefield TM, Willis WT, Mandarino LJ"
> "Q9JL16-1","30232164","The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins.","mSphere","2018 Sep 19","Weiss CM, Trobaugh DW, Sun C, Lucas TM, Diamond MS, Ryman KD, Klimstra WB"
> "Q9JL16-1","19321657","Prevention of embryo loss in non-obese diabetic mice using adoptive ITGA2(+)ISG20(+) natural killer-cell transfer.","Reproduction (Cambridge, England)","2009 Jun","Lin Y, Wang H, Wang W, Zeng S, Zhong Y, Li DJ"
4012a4349
> "P01216-1","29054929","Mitogen- and stress-activated protein kinase 1 is required for gonadotropin-releasing hormone-mediated activation of gonadotropin alpha-subunit expression.","The Journal of biological chemistry","2017 Dec 15","Haj M, Wijeweera A, Rudnizky S, Taunton J, Pnueli L, Melamed P"
4022a4360,4371
> "Q63739-1","27899452","Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.","The Journal of biological chemistry","2017 Jan 20","Gimenez-Mascarell P, Oyenarte I, Hardy S, Breiderhoff T, Stuiver M, Kostantin E, Diercks T, Pey AL, Ereno-Orbea J, Martinez-Chantar ML, Khalaf-Nazzal R, Claverie-Martin F, Muller D, Tremblay ML, Martinez-Cruz LA"
> "Q8CIZ9-1","30154263","NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages.","mBio","2018 Aug 28","Matta SK, Patten K, Wang Q, Kim BH, MacMicking JD, Sibley LD"
> "Q8R0N9-1","23687301","In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.","The Journal of biological chemistry","2013 Jul 5","Oku S, Takahashi N, Fukata Y, Fukata M"
> "P61014-1","30299255","The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.","eLife","2018 Oct 9","Makarewich CA, Munir AZ, Schiattarella GG, Bezprozvannaya S, Raguimova ON, Cho EE, Vidal AH, Robia SL, Bassel-Duby R, Olson EN"
> "P70333-1","25846207","Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.","The journal of physiological sciences : JPS","2015 Jul","Hamada T, Miyakawa K, Kushige H, Shibata S, Kurachi S"
> "Q8VCW4-1","16415873","The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.","Nature immunology","2006 Feb","Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B"
> "Q3TJD7-1","27792740","Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice.","PloS one","2016","Urban AE, Quick EO, Miller KP, Krcmery J, Simon HG"
> "Q3TJD7-1","26556890","PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle.","The Biochemical journal","2016 Feb 1","D'Cruz R, Plant PJ, Pablo LA, Lin S, Chackowicz J, Correa J, Bain J, Batt J"
> "Q3TJD7-1","25677945","LIM Mineralization Protein-1 Enhances Bone Morphogenetic Protein-2-Mediated Osteogenesis Through Activation of ERK1/2 MAPK Pathway and Upregulation of Runx2 Transactivity.","Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research","2015 Aug","Pan H, Li X, Wang J, Zhang K, Yang H, Li Z, Zheng Z, Liu H"
> "Q3TJD7-1","25032549","Lim mineralization protein-1 knockout mice have reduced spine trabecular bone density on microcomputed tomography due to decreased bone morphogenetic protein responsiveness.","Neurosurgery","2014 Aug","Gary MF, Viggeswarapu M, Oliver C, Teklemariam M, Sangadala S, Titus L, Boden SD"
> "Q3TJD7-1","21060154","Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.","The Journal of clinical investigation","2010 Dec","Jung CR, Lim JH, Choi Y, Kim DG, Kang KJ, Noh SM, Im DS"
> "Q3TJD7-1","20706776","Immunohistochemical localization of LIM mineralization protein 1 during mouse molar development.","Journal of molecular histology","2010 Oct","Fang P, Wang X, Zhang L, Yuan G, Chen Z, Zhang Q"
4023a4373,4379
> "Q9Z0L2-1","28270618","Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.","Proceedings of the National Academy of Sciences of the United States of America","2017 Mar 21","Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G"
> "Q9Z0L2-1","25635057","Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels.","The Journal of biological chemistry","2015 Apr 17","Li S, Bhave D, Chow JM, Riera TV, Schlee S, Rauch S, Atanasova M, Cate RL, Whitty A"
> "Q9JKU8-1","29971487","A variant in LMX1A causes autosomal recessive severe-to-profound hearing impairment.","Human genetics","2018 Jul","Schrauwen I, Chakchouk I, Liaqat K, Jan A, Nasir A, Hussain S, Nickerson DA, Bamshad MJ, Ullah A, Ahmad W, Leal SM"
> "Q61818-1","30275311","Early adolescent Rai1 reactivation reverses transcriptional and social interaction deficits in a mouse model of Smith-Magenis syndrome.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 16","Huang WH, Wang DC, Allen WE, Klope M, Hu H, Shamloo M, Luo L"
> "Q61818-1","27693255","Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.","Neuron","2016 Oct 19","Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L"
> "Q61818-1","25752576","Viral pseudo-enzymes activate RIG-I via deamidation to evade cytokine production.","Molecular cell","2015 Apr 2","He S, Zhao J, Song S, He X, Minassian A, Zhou Y, Zhang J, Brulois K, Wang Y, Cabo J, Zandi E, Liang C, Jung JU, Zhang X, Feng P"
> "Q61818-1","25127133","Dietary regimens modify early onset of obesity in mice haploinsufficient for Rai1.","PloS one","2014","Alaimo JT, Hahn NC, Mullegama SV, Elsea SH"
4039c4395,4397
< "Q9ER62-1","29973541","Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy.","International journal of molecular sciences","2018 Jul 4","Uysal H, Chavez-Galan L, Vesin D, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I"
---
> "Q8VI36-1","28954813","Kindlin supports platelet integrin alphaIIbbeta3 activation by interacting with paxillin.","Journal of cell science","2017 Nov 1","Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, Hu Y, Zhang Y, Schulte ML, Jin C, Wang J, White GC, Xu Z, Ma YQ"
> "Q8BID6-1","22615130","Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage.","The Journal of experimental medicine","2012 Jun 4","Meredith MM, Liu K, Darrasse-Jeze G, Kamphorst AO, Schreiber HA, Guermonprez P, Idoyaga J, Cheong C, Yao KH, Niec RE, Nussenzweig MC"
> "Q8BID6-1","22615127","Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.","The Journal of experimental medicine","2012 Jun 4","Satpathy AT, KC W, Albring JC, Edelson BT, Kretzer NM, Bhattacharya D, Murphy TL, Murphy KM"
4042a4401,4404
> "P97368-1","22987645","Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.","Developmental dynamics : an official publication of the American Association of Anatomists","2012 Nov","Sonnet W, Rezsohazy R, Donnay I"
> "P97368-1","21059917","Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1.","Proceedings of the National Academy of Sciences of the United States of America","2010 Nov 23","Liu J, Wang Y, Birnbaum MJ, Stoffers DA"
> "P97368-1","18223676","Acceleration of chronic myeloproliferation by enforced expression of Meis1 or Meis3 in Icsbp-deficient bone marrow cells.","Oncogene","2008 Jun 19","Hara T, Schwieger M, Kazama R, Okamoto S, Minehata K, Ziegler M, Lohler J, Stocking C"
> "P97368-1","12397630","PBX, MEIS, and IGF-I are potential mediators of retinoic acid-induced proximodistal limb reduction defects.","Teratology","2002 Nov","Qin P, Cimildoro R, Kochhar DM, Soprano KJ, Soprano DR"
4044a4407,4408
> "Q8BPM6-1","27129882","RIC-3 expression and splicing regulate nAChR functional expression.","Molecular brain","2016 Apr 29","Ben-David Y, Mizrachi T, Kagan S, Krisher T, Cohen E, Brenner T, Treinin M"
> "Q8BPM6-1","20668195","Ric-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2010 Jul 28","Alexander JK, Sagher D, Krivoshein AV, Criado M, Jefford G, Green WN"
4046,4047c4410
< "Q9D6Z0-1","28726787","ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage.","Cell death &amp; disease","2017 Jul 20","Jordan JJ, Chhim S, Margulies CM, Allocca M, Bronson RT, Klungland A, Samson LD, Fu D"
< "Q9D6Z0-1","23572141","Deletion of mouse Alkbh7 leads to obesity.","Journal of molecular cell biology","2013 Jun","Solberg A, Robertson AB, Aronsen JM, Rognmo O, Sjaastad I, Wisloff U, Klungland A"
---
> "P51432-1","26468229","Gnb isoforms control a signaling pathway comprising Rac1, Plcbeta2, and Plcbeta3 leading to LFA-1 activation and neutrophil arrest in vivo.","Blood","2016 Jan 21","Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A"
4051a4415,4416
> "Q6P069-1","26822088","Sorcin Links Pancreatic beta-Cell Lipotoxicity to ER Ca2+ Stores.","Diabetes","2016 Apr","Marmugi A, Parnis J, Chen X, Carmichael L, Hardy J, Mannan N, Marchetti P, Piemonti L, Bosco D, Johnson P, Shapiro JA, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Thorens B, Valdivia HH, Rutter GA, Leclerc I"
> "Q6P069-1","12824171","Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart.","The Journal of biological chemistry","2003 Sep 5","Farrell EF, Antaramian A, Rueda A, Gomez AM, Valdivia HH"
4054a4420,4426
> "Q8CAS9-1","27796300","PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.","Nature communications","2016 Oct 31","Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabasi AL, Boothby M, Aikawa E, Singh SA, Aikawa M"
> "Q8CAS9-1","26479788","PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.","Nature immunology","2015 Dec","Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ"
> "Q8CAS9-1","18069692","The macroPARP genes Parp-9 and Parp-14 are developmentally and differentially regulated in mouse tissues.","Developmental dynamics : an official publication of the American Association of Anatomists","2008 Jan","Hakme A, Huber A, Dolle P, Schreiber V"
> "O88576-1","26240152","Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin.","The Journal of biological chemistry","2015 Oct 2","Fairweather SJ, Broer A, Subramanian N, Tumer E, Cheng Q, Schmoll D, O'Mara ML, Broer S"
> "O88576-1","19478081","Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3.","The Journal of biological chemistry","2009 Jul 24","Singer D, Camargo SM, Huggel K, Romeo E, Danilczyk U, Kuba K, Chesnov S, Caron MG, Penninger JM, Verrey F"
> "O88576-1","15121838","Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.","Molecular and cellular biology","2004 May","Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG"
> "Q9Z131-1","25666017","Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.","Journal of hepatology","2015 Jun","Win S, Than TA, Le BH, Garcia-Ruiz C, Fernandez-Checa JC, Kaplowitz N"
4065a4438,4440
> "A2ASZ8-1","28588221","Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway that might be involved in muscle thermogenesis.","Scientific reports","2017 Jun 6","Nakao R, Shimba S, Oishi K"
> "A2ASZ8-1","21296886","Inactivation of the mitochondrial carrier SLC25A25 (ATP-Mg2+/Pi transporter) reduces physical endurance and metabolic efficiency in mice.","The Journal of biological chemistry","2011 Apr 1","Anunciado-Koza RP, Zhang J, Ukropec J, Bajpeyi S, Koza RA, Rogers RC, Cefalu WT, Mynatt RL, Kozak LP"
> "Q80YA3-1","24599962","Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics.","The Journal of biological chemistry","2014 Apr 18","Baba T, Kashiwagi Y, Arimitsu N, Kogure T, Edo A, Maruyama T, Nakao K, Nakanishi H, Kinoshita M, Frohman MA, Yamamoto A, Tani K"
4067,4072c4442,4446
< "Q8C0R7-1","20675388","Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility.","The Journal of biological chemistry","2010 Oct 8","Yan W, Si Y, Slaymaker S, Li J, Zheng H, Young DL, Aslanian A, Saunders L, Verdin E, Charo IF"
< "Q18PE0-1","28069867","The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation.","Journal of biochemistry","2017 Mar 1","Ueta R, Tezuka T, Izawa Y, Miyoshi S, Nagatoishi S, Tsumoto K, Yamanashi Y"
< "Q18PE0-1","27091576","Postnatal knockdown of dok-7 gene expression in mice causes structural defects in neuromuscular synapses and myasthenic pathology.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2016 Jun","Eguchi T, Tezuka T, Miyoshi S, Yamanashi Y"
< "Q18PE0-1","26198629","Protein kinase CK2 interacts at the neuromuscular synapse with Rapsyn, Rac1, 14-3-3gamma, and Dok-7 proteins and phosphorylates the latter two.","The Journal of biological chemistry","2015 Sep 11","Herrmann D, Straubinger M, Hashemolhosseini S"
< "Q18PE0-1","18165682","Mutations causing DOK7 congenital myasthenia ablate functional motifs in Dok-7.","The Journal of biological chemistry","2008 Feb 29","Hamuro J, Higuchi O, Okada K, Ueno M, Iemura S, Natsume T, Spearman H, Beeson D, Yamanashi Y"
< "Q18PE0-1","16794080","The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.","Science (New York, N.Y.)","2006 Jun 23","Okada K, Inoue A, Okada M, Murata Y, Kakuta S, Jigami T, Kubo S, Shiraishi H, Eguchi K, Motomura M, Akiyama T, Iwakura Y, Higuchi O, Yamanashi Y"
---
> "P61793-1","30622227","HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells.","Molecules and cells","2019 Feb 28","Kim NH, Sadra A, Park HY, Oh SM, Chun J, Yoon JK, Huh SO"
> "P61793-1","29051083","Lysophosphatidic acid propagates post-injury Schwann cell dedifferentiation through LPA1 signaling.","Neuroscience letters","2018 Jan 1","Szepanowski F, Szepanowski LP, Mausberg AK, Kleinschnitz C, Kieseier BC, Stettner M"
> "P0DPB4-1","27979964","Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.","The Journal of biological chemistry","2017 Feb 10","Martin PM, Cifuentes-Diaz C, Devaux J, Garcia M, Bureau J, Thomasseau S, Klingler E, Girault JA, Goutebroze L"
> "P0DPB4-1","25950943","CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.","Journal of neurochemistry","2015 Aug","Papandreou MJ, Vacher H, Fache MP, Klingler E, Rueda-Boroni F, Ferracci G, Debarnot C, Piperoglou C, Garcia Del Cano G, Goutebroze L, Dargent B"
> "P0DPB4-1","25953347","The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.","Development (Cambridge, England)","2015 Jun 1","Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chedotal A, Girault JA, Goutebroze L"
4074,4075d4447
< "Q8BKX1-1","28067313","Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development.","Scientific reports","2017 Jan 9","Chou AM, Sem KP, Lam WJ, Ahmed S, Lim CY"
< "Q924W7-1","29650351","Overexpression of ST5, an activator of Ras, has no effect on beta-cell proliferation in adult mice.","Molecular metabolism","2018 May","Ou K, Zhang J, Jiao Y, Wang ZV, Scherer P, Kaestner KH"
4077c4449
< "Q62432-1","30651315","Uterine double-conditional inactivation of Smad2 and Smad3 in mice causes endometrial dysregulation, infertility, and uterine cancer.","Proceedings of the National Academy of Sciences of the United States of America","2019 Feb 26","Kriseman M, Monsivais D, Agno J, Masand RP, Creighton CJ, Matzuk MM"
---
> "Q5BLK4-1","28665939","The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.","PloS one","2017","Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR"
4091,4102c4463
< "Q9R1T4-1","29400567","Regulatory network analysis of hypertension and hypotension microarray data from mouse model.","Clinical and experimental hypertension (New York, N.Y. : 1993)","2018","Zhu Y, Zhuo J, Li C, Wang Q, Liu X, Ye L"
< "Q9R1T4-1","28751190","Septin 6 regulates engraftment and lymphoid differentiation potential of murine long-term hematopoietic stem cells.","Experimental hematology","2017 Nov","Senger K, Marka G, Soller K, Sakk V, Florian MC, Geiger H"
< "O35474-1","12074641","The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation.","Microvascular research","2002 Jul","Aoka Y, Johnson FL, Penta K, Hirata Ki K, Hidai C, Schatzman R, Varner JA, Quertermous T"
< "O35474-1","11959660","Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3).","American journal of physiology. Heart and circulatory physiology","2002 May","Rezaee M, Penta K, Quertermous T"
< "Q9WTJ6-1","14648882","Tesmin transcription is regulated differently during male and female meiosis.","Molecular reproduction and development","2004 Jan","Olesen C, Moller M, Byskov AG"
< "Q9WTJ6-1","12606435","Native tesmin is a 60-kilodalton protein that undergoes dynamic changes in its localization during spermatogenesis in mice.","Biology of reproduction","2003 May","Sutou S, Miwa K, Matsuura T, Kawasaki Y, Ohinata Y, Mitsui Y"
< "Q9WTJ6-1","11803038","Germ cell-specific nucleocytoplasmic shuttling protein, tesmin, responsive to heavy metal stress in mouse testes.","Journal of inorganic biochemistry","2002 Jan 15","Matsuura T, Kawasaki Y, Miwa K, Sutou S, Ohinata Y, Yoshida F, Mitsui Y"
< "Q99N50-1","24284068","Slp2-a controls renal epithelial cell size through regulation of Rap-ezrin signaling independently of Rab27.","Journal of cell science","2014 Feb 1","Yasuda T, Fukuda M"
< "Q99N50-1","22767581","Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.","Molecular biology of the cell","2012 Aug","Yasuda T, Saegusa C, Kamakura S, Sumimoto H, Fukuda M"
< "Q99N50-1","20729199","Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.","The Journal of biological chemistry","2010 Oct 29","Pang ZP, Xu W, Cao P, Sudhof TC"
< "Q99N50-1","15543135","Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.","Nature cell biology","2004 Dec","Kuroda TS, Fukuda M"
< "Q99N50-1","11773082","The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.","The Journal of biological chemistry","2002 Mar 15","Kuroda TS, Fukuda M, Ariga H, Mikoshiba K"
---
> "Q99N48-1","11773082","The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.","The Journal of biological chemistry","2002 Mar 15","Kuroda TS, Fukuda M, Ariga H, Mikoshiba K"
4104,4110c4465,4470
< "Q80U04-1","27195677","praja2 regulates KSR1 stability and mitogenic signaling.","Cell death &amp; disease","2016 May 19","Rinaldi L, Delle Donne R, Sepe M, Porpora M, Garbi C, Chiuso F, Gallo A, Parisi S, Russo L, Bachmann V, Huber RG, Stefan E, Russo T, Feliciello A"
< "Q80U04-1","24561619","Role of the SIK2-p35-PJA2 complex in pancreatic beta-cell functional compensation.","Nature cell biology","2014 Mar","Sakamaki J, Fu A, Reeks C, Baird S, Depatie C, Al Azzabi M, Bardeesy N, Gingras AC, Yee SP, Screaton RA"
< "Q8BPM0-1","28682694","Daam1 regulates fascin for actin assembly in mouse oocyte meiosis.","Cell cycle (Georgetown, Tex.)","2017 Jul 18","Lu Y, Zhang Y, Pan MH, Kim NH, Sun SC, Cui XS"
< "Q8BPM0-1","27807130","DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility.","The Journal of cell biology","2016 Nov 21","Nishimura T, Ito S, Saito H, Hiver S, Shigetomi K, Ikenouchi J, Takeichi M"
< "Q8BPM0-1","27760153","Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network.","PloS one","2016","Luo W, Lieu ZZ, Manser E, Bershadsky AD, Sheetz MP"
< "Q8BPM0-1","15533824","Identification and comparative expression analyses of Daam genes in mouse and Xenopus.","Gene expression patterns : GEP","2004 Nov","Nakaya MA, Habas R, Biris K, Dunty WC Jr, Kato Y, He X, Yamaguchi TP"
< "Q8BPM0-1","15464228","Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.","Brain research. Developmental brain research","2004 Oct 15","Kida Y, Shiraishi T, Ogura T"
---
> "Q3UHK3-1","29955957","De novo variants in GREB1L are associated with non-syndromic inner ear malformations and deafness.","Human genetics","2018 Jul","Schrauwen I, Kari E, Mattox J, Llaci L, Smeeton J, Naymik M, Raible DW, Knowles JA, Crump JG, Huentelman MJ, Friedman RA"
> "Q3UHK3-1","29100091","Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice.","American journal of human genetics","2017 Nov 2","De Tomasi L, David P, Humbert C, Silbermann F, Arrondel C, Tores F, Fouquet S, Desgrange A, Niel O, Bole-Feysot C, Nitschke P, Roume J, Cordier MP, Pietrement C, Isidor B, Khau Van Kien P, Gonzales M, Saint-Frison MH, Martinovic J, Novo R, Piard J, Cabrol C, Verma IC, Puri R, Journel H, Aziza J, Gavard L, Said-Menthon MH, Heidet L, Saunier S, Jeanpierre C"
> "Q06180-1","29712668","TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding.","Diabetes","2018 Jul","Dodd GT, Lee-Young RS, Bruning JC, Tiganis T"
> "Q06180-1","29444435","PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer.","Cell reports","2018 Feb 13","Spalinger MR, Manzini R, Hering L, Riggs JB, Gottier C, Lang S, Atrott K, Fettelschoss A, Olomski F, Kundig TM, Fried M, McCole DF, Rogler G, Scharl M"
> "Q06180-1","29587266","Overexpression of PTPN2 in Visceral Adipose Tissue Ameliorated Atherosclerosis via T Cells Polarization Shift in Diabetic Apoe-/- Mice.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2018","Li Y, Zhou H, Wang F, Han L, Liu M, Li Y, Wang Z, Tang M, Zhang W, Zhong M"
> "Q7TN99-1","12871996","Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus.","Proceedings of the National Academy of Sciences of the United States of America","2003 Aug 5","Theis M, Si K, Kandel ER"
4112,4115d4471
< "Q9R0U0-1","26586428","SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.","Cell reports","2015 Nov 24","Wei N, Cheng Y, Wang Z, Liu Y, Luo C, Liu L, Chen L, Xie Z, Lu Y, Feng Y"
< "Q9R0U0-1","25627895","Splicing factor NSSR1 reduces neuronal injury after mouse transient global cerebral ischemia.","Glia","2015 May","Qi Y, Li Y, Cui SC, Zhao JJ, Liu XY, Ji CX, Sun FY, Xu P, Chen XH"
< "Q9R0U0-1","24710272","SRSF10 regulates alternative splicing and is required for adipocyte differentiation.","Molecular and cellular biology","2014 Jun","Li H, Cheng Y, Wu W, Liu Y, Wei N, Feng X, Xie Z, Feng Y"
< "Q9R0U0-1","24668663","Dephosphorylation of NSSR1 regulates alternative splicing of the GluR-B minigene.","Genetics and molecular research : GMR","2014 Mar 17","Zhang W, Li LL, Chen XH, Peng ZY"
4118a4475,4477
> "Q2VPU4-1","29282201","MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic beta-Cells.","Diabetes","2018 Mar","Richards P, Rachdi L, Oshima M, Marchetti P, Bugliani M, Armanet M, Postic C, Guilmeau S, Scharfmann R"
> "Q2VPU4-1","27500491","MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling.","The Journal of clinical investigation","2016 Sep 1","Ahn B, Soundarapandian MM, Sessions H, Peddibhotla S, Roth GP, Li JL, Sugarman E, Koo A, Malany S, Wang M, Yea K, Brooks J, Leone TC, Han X, Vega RB, Kelly DP"
> "Q2VPU4-1","26910886","Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.","PloS one","2016","Singh P, Irwin DM"
4121a4481,4482
> "Q8C078-1","28981105","Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration.","Cell death &amp; disease","2017 Oct 5","Racioppi L, Lento W, Huang W, Arvai S, Doan PL, Harris JR, Marcon F, Nakaya HI, Liu Y, Chao N"
> "Q8C078-1","14586002","Loss of Ca2+/calmodulin kinase kinase beta affects the formation of some, but not all, types of hippocampus-dependent long-term memory.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2003 Oct 29","Peters M, Mizuno K, Ris L, Angelo M, Godaux E, Giese KP"
4128a4490
> "Q5SSM3-1","11431473","Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1.","The Journal of biological chemistry","2001 Sep 14","Richnau N, Aspenstrom P"
4131,4133d4492
< "Q04646-1","25633594","FXYD2, a gamma subunit of Na(+), K(+)-ATPase, maintains persistent mechanical allodynia induced by inflammation.","Cell research","2015 Mar","Wang F, Cai B, Li KC, Hu XY, Lu YJ, Wang Q, Bao L, Zhang X"
< "Q04646-1","23344951","Hyperplasia of pancreatic beta cells and improved glucose tolerance in mice deficient in the FXYD2 subunit of Na,K-ATPase.","The Journal of biological chemistry","2013 Mar 8","Arystarkhova E, Liu YB, Salazar C, Stanojevic V, Clifford RJ, Kaplan JH, Kidder GM, Sweadner KJ"
< "Q04646-1","22253804","Regulation of the Na,K-ATPase gamma-subunit FXYD2 by Runx1 and Ret signaling in normal and injured non-peptidergic nociceptive sensory neurons.","PloS one","2012","Venteo S, Bourane S, Mechaly I, Sar C, Abdel Samad O, Puech S, Blostein R, Valmier J, Pattyn A, Carroll P"
4144,4148d4502
< "Q8BX22-1","22385656","Functional antagonism between Sall4 and Plzf defines germline progenitors.","Cell stem cell","2012 Mar 2","Hobbs RM, Fagoonee S, Papa A, Webster K, Altruda F, Nishinakamura R, Chai L, Pandolfi PP"
< "Q8BX22-1","17060609","Murine inner cell mass-derived lineages depend on Sall4 function.","Proceedings of the National Academy of Sciences of the United States of America","2006 Oct 31","Elling U, Klasen C, Eisenberger T, Anlag K, Treier M"
< "Q8BX22-1","16790473","The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.","Development (Cambridge, England)","2006 Aug","Sakaki-Yumoto M, Kobayashi C, Sato A, Fujimura S, Matsumoto Y, Takasato M, Kodama T, Aburatani H, Asashima M, Yoshida N, Nishinakamura R"
< "Q8BX22-1","16380715","Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.","Nature genetics","2006 Feb","Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG"
< "Q8BX22-1","12826753","Cloning and expression analysis of SALL4, the murine homologue of the gene mutated in Okihiro syndrome.","Cytogenetic and genome research","2002","Kohlhase J, Heinrich M, Liebers M, Frohlich Archangelo L, Reardon W, Kispert A"
4158,4167c4512,4516
< "Q7TS63-1","27591365","Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.","Biochimica et biophysica acta","2016 Nov","Ishikura S, Tsunoda T, Nakabayashi K, Doi K, Koyanagi M, Hayashi K, Kawai T, Tanaka Y, Iwaihara Y, Luo H, Nishi K, Okamura T, Shirasawa S"
< "Q7TS63-1","27226588","The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway.","The Journal of biological chemistry","2016 Jul 15","Ishikura S, Iwaihara Y, Tanaka Y, Luo H, Nishi K, Doi K, Koyanagi M, Okamura T, Tsunoda T, Shirasawa S"
< "Q7TS63-1","26168481","Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells.","Anticancer research","2015 Aug","Iwaihara Y, Ishikura S, Doi K, Tsunoda T, Fujimoto T, Okamura T, Shirasawa S"
< "Q7TS63-1","21225468","ZFAT is a critical molecule for cell survival in mouse embryonic fibroblasts.","Cellular &amp; molecular biology letters","2011 Mar","Doi K, Fujimoto T, Koyanagi M, Tsunoda T, Tanaka Y, Yoshida Y, Takashima Y, Kuroki M, Sasazuki T, Shirasawa S"
< "Q7TS63-1","20660741","Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands.","Proceedings of the National Academy of Sciences of the United States of America","2010 Aug 10","Tsunoda T, Takashima Y, Tanaka Y, Fujimoto T, Doi K, Hirose Y, Koyanagi M, Yoshida Y, Okamura T, Kuroki M, Sasazuki T, Shirasawa S"
< "Q7TS63-1","18329245","ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes.","Genomics","2008 May","Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S"
< "Q3UQI9-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
< "P42866-1","30738575","In vitro and in vivo characterization of the bifunctional mu- and delta- opioid receptors ligand MCRT on mouse gastrointestinal motility.","Neuropeptides","2019 Apr","He C, Li H, Zhang J, Zhou L, Dong S"
< "P42866-1","30664663","Phosphorylation-deficient G-protein-biased mu-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects.","Nature communications","2019 Jan 21","Kliewer A, Schmiedel F, Sianati S, Bailey A, Bateman JT, Levitt ES, Williams JT, Christie MJ, Schulz S"
< "P42866-1","17284463","Translational repression of mouse mu opioid receptor expression via leaky scanning.","Nucleic acids research","2007","Song KY, Hwang CK, Kim CS, Choi HS, Law PY, Wei LN, Loh HH"
---
> "Q9CWZ3-1","28916722","Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing.","The Journal of biological chemistry","2017 Nov 3","Shinde MY, Sidoli S, Kulej K, Mallory MJ, Radens CM, Reicherter AL, Myers RL, Barash Y, Lynch KW, Garcia BA, Klein PS"
> "Q9CWZ3-1","28404883","miR-29a regulates the proliferation and differentiation of retinal progenitors by targeting Rbm8a.","Oncotarget","2017 May 9","Zhang Y, Shen B, Zhang D, Wang Y, Tang Z, Ni N, Jin X, Luo M, Sun H, Gu P"
> "Q9CWZ3-1","27618312","Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.","PLoS genetics","2016 Sep","Mao H, McMahon JJ, Tsai YH, Wang Z, Silver DL"
> "Q9CWZ3-1","26094033","A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.","Neural development","2015 Jun 21","Zou D, McSweeney C, Sebastian A, Reynolds DJ, Dong F, Zhou Y, Deng D, Wang Y, Liu L, Zhu J, Zou J, Shi Y, Albert I, Mao Y"
> "Q9CWZ3-1","23638902","An EJC factor RBM8a regulates anxiety behaviors.","Current molecular medicine","2013 Jul","Alachkar A, Jiang D, Harrison M, Zhou Y, Chen G, Mao Y"
4175a4525,4527
> "Q3UWA6-1","29367634","Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens.","Scientific reports","2018 Jan 24","Amarachintha S, Harmel-Laws E, Steinbrecher KA"
> "Q3UWA6-1","28916678","GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.","Cancer research","2017 Sep 15","Li P, Wuthrick E, Rappaport JA, Kraft C, Lin JE, Marszalowicz G, Snook AE, Zhan T, Hyslop TM, Waldman SA"
> "Q3UWA6-1","26773096","Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.","Cancer research","2016 Jan 15","Lin JE, Colon-Gonzalez F, Blomain E, Kim GW, Aing A, Stoecker B, Rock J, Snook AE, Zhan T, Hyslop TM, Tomczak M, Blumberg RS, Waldman SA"
4177a4530,4542
> "Q3U108-1","29244194","Arid5a stabilizes OX40 mRNA in murine CD4(+) T cells by recognizing a stem-loop structure in its 3'UTR.","European journal of immunology","2018 Apr","Hanieh H, Masuda K, Metwally H, Chalise JP, Mohamed M, Nyati KK, Standley DM, Li S, Higa M, Zaman MM, Kishimoto T"
> "Q3U108-1","29358370","Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a.","Proceedings of the National Academy of Sciences of the United States of America","2018 Feb 6","Higa M, Oka M, Fujihara Y, Masuda K, Yoneda Y, Kishimoto T"
> "Q3U108-1","28168301","TLR4-induced NF-kappaB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a.","Nucleic acids research","2017 Mar 17","Nyati KK, Masuda K, Zaman MM, Dubey PK, Millrine D, Chalise JP, Higa M, Li S, Standley DM, Saito K, Hanieh H, Kishimoto T"
> "Q3U108-1","28379390","Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury.","International immunology","2017 Feb 1","Dubey PK, Masuda K, Nyati KK, -Uz Zaman MM, Chalise JP, Millrine D, Kai W, Ripley B, Kishimoto T"
> "Q3U108-1","27671645","Arid5a exacerbates IFN-gamma-mediated septic shock by stabilizing T-bet mRNA.","Proceedings of the National Academy of Sciences of the United States of America","2016 Oct 11","Zaman MM, Masuda K, Nyati KK, Dubey PK, Ripley B, Wang K, Chalise JP, Higa M, Hanieh H, Kishimoto T"
> "Q3U108-1","27022145","Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.","The Journal of experimental medicine","2016 Apr 4","Masuda K, Ripley B, Nyati KK, Dubey PK, Zaman MM, Hanieh H, Higa M, Yamashita K, Standley DM, Mashima T, Katahira M, Okamoto T, Matsuura Y, Takeuchi O, Kishimoto T"
> "Q3U108-1","23676272","Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo.","Proceedings of the National Academy of Sciences of the United States of America","2013 Jun 4","Masuda K, Ripley B, Nishimura R, Mino T, Takeuchi O, Shioi G, Kiyonari H, Kishimoto T"
> "Q3U108-1","21346191","Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription.","Molecular biology of the cell","2011 Apr 15","Amano K, Hata K, Muramatsu S, Wakabayashi M, Takigawa Y, Ono K, Nakanishi M, Takashima R, Kogo M, Matsuda A, Nishimura R, Yoneda T"
> "E9PYI1-1","28522536","A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568.","Science (New York, N.Y.)","2017 May 19","Yang P, Wang Y, Hoang D, Tinkham M, Patel A, Sun MA, Wolf G, Baker M, Chien HC, Lai KN, Cheng X, Shen CJ, Macfarlan TS"
> "E9PYI1-1","23071813","Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage.","PloS one","2012","Chien HC, Wang HY, Su YN, Lai KY, Lu LC, Chen PC, Tsai SF, Wu CI, Hsieh WS, Shen CK"
> "E9PYI1-1","22110054","TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.","Development (Cambridge, England)","2011 Dec","Shibata M, Blauvelt KE, Liem KF Jr, Garcia-Garcia MJ"
> "E9PYI1-1","21094155","The mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesis.","Developmental biology","2011 Jan 15","Shibata M, Garcia-Garcia MJ"
> "E9PYI1-1","18701545","Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.","Development (Cambridge, England)","2008 Sep","Garcia-Garcia MJ, Shibata M, Anderson KV"
4181,4182d4545
< "Q9D8F1-1","25153837","ALKBH4 depletion in mice leads to spermatogenic defects.","PloS one","2014","Nilsen A, Fusser M, Greggains G, Fedorcsak P, Klungland A"
< "Q9D8F1-1","23673617","ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.","Nature communications","2013","Li MM, Nilsen A, Shi Y, Fusser M, Ding YH, Fu Y, Liu B, Niu Y, Wu YS, Huang CM, Olofsson M, Jin KX, Lv Y, Xu XZ, He C, Dong MQ, Rendtlew Danielsen JM, Klungland A, Yang YG"
4187d4549
< "P48678-1","21327075","Dynamic properties of meiosis-specific lamin C2 and its impact on nuclear envelope integrity.","Nucleus (Austin, Tex.)","2010 May-Jun","Jahn D, Schramm S, Benavente R, Alsheimer M"
4189a4552,4556
> "Q3U1T9-1","26774822","Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease.","Cell","2016 Jan 14","Yang CW, Hojer CD, Zhou M, Wu X, Wuster A, Lee WP, Yaspan BL, Chan AC"
> "Q8BJ56-1","29320510","Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.","PLoS genetics","2018 Jan","Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U"
> "Q8BJ56-1","16009485","Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes.","Molecular and cellular endocrinology","2005 Aug 30","Kralisch S, Klein J, Lossner U, Bluher M, Paschke R, Stumvoll M, Fasshauer M"
> "Q8BJ56-1","15550674","Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.","Science (New York, N.Y.)","2004 Nov 19","Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A, Zechner R"
> "Q8BJ56-1","15337759","Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.","The Journal of biological chemistry","2004 Nov 5","Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS"
4194a4562,4564
> "Q8VEK6-1","25819753","ING3 protein expression profiling in normal human tissues suggest its role in cellular growth and self-renewal.","European journal of cell biology","2015 May","Nabbi A, Almami A, Thakur S, Suzuki K, Boland D, Bismar TA, Riabowol K"
> "Q9CY57-1","20688955","Fetal globin expression is regulated by Friend of Prmt1.","Blood","2010 Nov 18","van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S"
> "Q9CY57-1","19858291","Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.","Molecular and cellular biology","2010 Jan","van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S"
4195a4566,4567
> "Q9WUB0-1","30254289","LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.","Nature communications","2018 Sep 25","Taraborrelli L, Peltzer N, Montinaro A, Kupka S, Rieser E, Hartwig T, Sarr A, Darding M, Draber P, Haas TL, Akarca A, Marafioti T, Pasparakis M, Bertin J, Gough PJ, Bouillet P, Strasser A, Leverkus M, Silke J, Walczak H"
> "Q9WUB0-1","29695863","LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.","Nature","2018 May","Peltzer N, Darding M, Montinaro A, Draber P, Draberova H, Kupka S, Rieser E, Fisher A, Hutchinson C, Taraborrelli L, Hartwig T, Lafont E, Haas TL, Shimizu Y, Boiers C, Sarr A, Rickard J, Alvarez-Diaz S, Ashworth MT, Beal A, Enver T, Bertin J, Kaiser W, Strasser A, Silke J, Bouillet P, Walczak H"
4197,4208c4569,4576
< "P97379-1","22357953","Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.","Journal of cell science","2012 May 15","Bikkavilli RK, Malbon CC"
< "Q0GGX2-1","18849567","A novel germ cell-specific protein, SHIP1, forms a complex with chromatin remodeling activity during spermatogenesis.","The Journal of biological chemistry","2008 Dec 12","Choi E, Han C, Park I, Lee B, Jin S, Choi H, Kim DH, Park ZY, Eddy EM, Cho C"
< "Q2MH31-1","19213785","Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development.","The European respiratory journal","2009 May","Haitchi HM, Yoshisue H, Ribbene A, Wilson SJ, Holloway JW, Bucchieri F, Hanley NA, Wilson DI, Zummo G, Holgate ST, Davies DE"
< "Q2MH31-1","18163442","Isolation and characterization of the spermatid-specific Smrp1 gene encoding a novel manchette protein.","Molecular reproduction and development","2008 Jun","Matsuoka Y, Miyagawa Y, Tokuhiro K, Kitamura K, Iguchi N, Maekawa M, Takahashi T, Tsujimura A, Matsumiya K, Okuyama A, Nishimune Y, Tanaka H"
< "Q2MH31-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
< "Q8BXR9-1","26941018","miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux.","Arteriosclerosis, thrombosis, and vascular biology","2016 May","Ouimet M, Hennessy EJ, van Solingen C, Koelwyn GJ, Hussein MA, Ramkhelawon B, Rayner KJ, Temel RE, Perisic L, Hedin U, Maegdefessel L, Garabedian MJ, Holdt LM, Teupser D, Moore KJ"
< "Q99P72-2","30055160","Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury.","Experimental neurology","2018 Nov","Meves JM, Geoffroy CG, Kim ND, Kim JJ, Zheng B"
< "Q99P72-2","30051920","Nogo-A inhibits vascular regeneration in ischemic retinopathy.","Glia","2018 Oct","Joly S, Dejda A, Rodriguez L, Sapieha P, Pernet V"
< "Q99P72-2","30040841","Loss of Nogo-A, encoded by the schizophrenia risk gene Rtn4, reduces mGlu3 expression and causes hyperexcitability in hippocampal CA3 circuits.","PloS one","2018","Berry S, Weinmann O, Fritz AK, Rust R, Wolfer D, Schwab ME, Gerber U, Ster J"
< "Q99P72-2","12225863","Expression of Nogo protein by growing axons in the developing nervous system.","Brain research. Molecular brain research","2002 Aug 15","Tozaki H, Kawasaki T, Takagi Y, Hirata T"
< "Q8BG26-1","22404429","Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons.","Journal of neurochemistry","2012 Jun","MacDonald JI, Dietrich A, Gamble S, Hryciw T, Grant RI, Meakin SO"
< "Q8BG26-1","15024033","Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth.","The Journal of cell biology","2004 Mar 15","MacDonald JI, Kubu CJ, Meakin SO"
---
> "Q811D0-1","29995933","SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus.","PloS one","2018","Gupta P, Uner OE, Nayak S, Grant GR, Kalb RG"
> "Q811D0-1","28103480","Adrenergic Gate Release for Spike Timing-Dependent Synaptic Potentiation.","Neuron","2017 Jan 18","Liu Y, Cui L, Schwarz MK, Dong Y, Schluter OM"
> "Q80VW5-1","28966015","Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem.","Structure (London, England : 1993)","2017 Nov 7","Delhommel F, Cordier F, Bardiaux B, Bouvier G, Colcombet-Cazenave B, Brier S, Raynal B, Nouaille S, Bahloul A, Chamot-Rooke J, Nilges M, Petit C, Wolff N"
> "Q80VW5-1","28387217","Defective Gpsm2/Galphai3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.","Nature communications","2017 Apr 7","Mauriac SA, Hien YE, Bird JE, Carvalho SD, Peyroutou R, Lee SC, Moreau MM, Blanc JM, Geyser A, Medina C, Thoumine O, Beer-Hammer S, Friedman TB, Ruttiger L, Forge A, Nurnberg B, Sans N, Montcouquiol M"
> "Q9ESG2-1","20731842","CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.","Reproductive biology and endocrinology : RB&amp;E","2010 Aug 23","Li YF, He W, Kim YH, Mandal A, Digilio L, Klotz K, Flickinger CJ, Herr JC"
> "Q8CGF7-1","21365688","The ensemble folding kinetics of the FBP28 WW domain revealed by an all-atom Monte Carlo simulation in a knowledge-based potential.","Proteins","2011 Jun","Xu J, Huang L, Shakhnovich EI"
> "Q8CGF7-1","16784750","Phi-analysis at the experimental limits: mechanism of beta-hairpin formation.","Journal of molecular biology","2006 Jul 21","Petrovich M, Jonsson AL, Ferguson N, Daggett V, Fersht AR"
> "D3Z7P3-1","30472430","GLS1 Mutant Mice Display Moderate Alterations of Hippocampal Glutamatergic Neurotransmission Associated with Specific Adaptive Behavioral Changes.","Neuroscience","2019 Jan 1","Dutar P, Tolle V, Kervern M, Carcenac C, Carola V, Gross C, Savasta M, Darmon M, Masson J"
4211a4580
> "Q5DTU0-1","27029000","XB130 deficiency enhances lipopolysaccharide-induced septic response and acute lung injury.","Oncotarget","2016 May 3","Toba H, Tomankova T, Wang Y, Bai X, Cho HR, Guan Z, Adeyi OA, Tian F, Keshavjee S, Liu M"
4213a4583
> "Q8BVD5-1","27001270","Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma.","BMC medical genomics","2016 Mar 22","Vishal M, Sharma A, Kaurani L, Alfano G, Mookherjee S, Narta K, Agrawal J, Bhattacharya I, Roychoudhury S, Ray J, Waseem NH, Bhattacharya SS, Basu A, Sen A, Ray K, Mukhopadhyay A"
4216a4587,4591
> "Q3US41-1","29324788","Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis.","PloS one","2018","Saeidi S, Shapouri F, de Iongh RU, Casagranda F, Sutherland JM, Western PS, McLaughlin EA, Familari M, Hime GR"
> "Q3US41-1","29107558","ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.","Developmental cell","2017 Nov 6","Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ"
> "Q3US41-1","19285943","ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.","Molecular cell","2009 Mar 13","Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP"
> "P59055-1","23076708","Differential promoter methylation and histone modification contribute to the brain specific expression of the mouse Mbu-1 gene.","Molecules and cells","2012 Nov","Kim B, Kang S, Kim SJ"
> "P59055-1","17433858","Characterization of a novel mouse brain gene (mbu-1) identified by digital differential display.","Gene","2007 Jun 15","Yang HL, Cho EY, Han KH, Kim H, Kim SJ"
4220,4225d4594
< "Q8R5M8-1","12202822","SynCAM, a synaptic adhesion molecule that drives synapse assembly.","Science (New York, N.Y.)","2002 Aug 30","Biederer T, Sara Y, Mozhayeva M, Atasoy D, Liu X, Kavalali ET, Sudhof TC"
< "Q8R5M8-1","12242005","Identification of the Tslc1 gene, a mouse orthologue of the human tumor suppressor TSLC1 gene.","Gene","2002 Jul 24","Fukami T, Satoh H, Fujita E, Maruyama T, Fukuhara H, Kuramochi M, Takamoto S, Momoi T, Murakami Y"
< "Q8BJ56-1","29320510","Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.","PLoS genetics","2018 Jan","Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U"
< "Q8BJ56-1","16009485","Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes.","Molecular and cellular endocrinology","2005 Aug 30","Kralisch S, Klein J, Lossner U, Bluher M, Paschke R, Stumvoll M, Fasshauer M"
< "Q8BJ56-1","15550674","Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.","Science (New York, N.Y.)","2004 Nov 19","Zimmermann R, Strauss JG, Haemmerle G, Schoiswohl G, Birner-Gruenberger R, Riederer M, Lass A, Neuberger G, Eisenhaber F, Hermetter A, Zechner R"
< "Q8BJ56-1","15337759","Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.","The Journal of biological chemistry","2004 Nov 5","Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS"
4228a4598,4599
> "Q8BG26-1","22404429","Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons.","Journal of neurochemistry","2012 Jun","MacDonald JI, Dietrich A, Gamble S, Hryciw T, Grant RI, Meakin SO"
> "Q8BG26-1","15024033","Nesca, a novel adapter, translocates to the nuclear envelope and regulates neurotrophin-induced neurite outgrowth.","The Journal of cell biology","2004 Mar 15","MacDonald JI, Kubu CJ, Meakin SO"
4231a4603
> "Q8C6B2-1","22503686","cGMP-dependent protein kinase I is involved in neurite outgrowth via a Rho effector, rhotekin, in Neuro2A neuroblastoma cells.","Biochemical and biophysical research communications","2012 May 4","Yuasa K, Nagame T, Dohi M, Yanagita Y, Yamagami S, Nagahama M, Tsuji A"
4234,4237d4605
< "Q6R0H7-1","30142336","GNAS(R201C) Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.","Gastroenterology","2018 Nov","Ideno N, Yamaguchi H, Ghosh B, Gupta S, Okumura T, Steffen DJ, Fisher CG, Wood LD, Singhi AD, Nakamura M, Gutkind JS, Maitra A"
< "Q6R0H7-1","15798190","Imprinted Nesp55 influences behavioral reactivity to novel environments.","Molecular and cellular biology","2005 Apr","Plagge A, Isles AR, Gordon E, Humby T, Dean W, Gritsch S, Fischer-Colbrie R, Wilkinson LS, Kelsey G"
< "Q6R0H7-1","15148396","XLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion Alex.","Proceedings of the National Academy of Sciences of the United States of America","2004 Jun 1","Abramowitz J, Grenet D, Birnbaumer M, Torres HN, Birnbaumer L"
< "Q6R0H7-1","10097123","A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2.","Proceedings of the National Academy of Sciences of the United States of America","1999 Mar 30","Peters J, Wroe SF, Wells CA, Miller HJ, Bodle D, Beechey CV, Williamson CM, Kelsey G"
4243a4612,4613
> "Q99PL8-1","22194418","Relative contribution of THTR-1 and THTR-2 in thiamin uptake by pancreatic acinar cells: studies utilizing Slc19a2 and Slc19a3 knockout mouse models.","American journal of physiology. Gastrointestinal and liver physiology","2012 Mar 1","Subramanian VS, Subramanya SB, Said HM"
> "Q99PL8-1","19423748","Pancreatic beta cells and islets take up thiamin by a regulated carrier-mediated process: studies using mice and human pancreatic preparations.","American journal of physiology. Gastrointestinal and liver physiology","2009 Jul","Mee L, Nabokina SM, Sekar VT, Subramanian VS, Maedler K, Said HM"
4246a4617,4623
> "Q6NZN1-1","25994039","Resistance to high-fat diet-induced obesity in male heterozygous Pprc1 knockout mice.","Endocrine journal","2015","Zhai N, Sun C, Gu W, He X, Shan A, Sun H, Lu N, Cui B, Ning G"
> "Q6NZN1-1","22411706","Peri-implantation lethality in mice lacking the PGC-1-related coactivator protein.","Developmental dynamics : an official publication of the American Association of Anatomists","2012 May","He X, Sun C, Wang F, Shan A, Guo T, Gu W, Cui B, Ning G"
> "Q14BU0-1","29720262","Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis.","Arthritis research &amp; therapy","2018 May 2","Seuffert F, Weidner D, Baum W, Schett G, Stock M"
> "Q14BU0-1","24867294","Insights into the association of Gla-rich protein and osteoarthritis, novel splice variants and gamma-carboxylation status.","Molecular nutrition &amp; food research","2014 Aug","Rafael MS, Cavaco S, Viegas CS, Santos S, Ramos A, Willems BA, Herfs M, Theuwissen E, Vermeer C, Simes DC"
> "Q14BU0-1","19819238","Identification of four alternatively spliced transcripts of the Ucma/GRP gene, encoding a new Gla-containing protein.","Experimental cell research","2010 Jan 15","Le Jeune M, Tomavo N, Tian TV, Flourens A, Marchand N, Camuzeaux B, Mallein-Gerin F, Duterque-Coquillaud M"
> "Q14BU0-1","18156182","Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis.","The Journal of biological chemistry","2008 Mar 14","Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J, Tagariello A, Onnerfjord P, Heinegard D, Schlotzer-Schrehardt U, Deutzmann R, von der Mark K, Stock M"
> "Q14BU0-1","17707622","Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes.","Matrix biology : journal of the International Society for Matrix Biology","2008 Jan","Tagariello A, Luther J, Streiter M, Didt-Koziel L, Wuelling M, Surmann-Schmitt C, Stock M, Adam N, Vortkamp A, Winterpacht A"
4260,4261c4637,4642
< "Q5BL07-1","15328346","Structure of the N-terminal domain of PEX1 AAA-ATPase. Characterization of a putative adaptor-binding domain.","The Journal of biological chemistry","2004 Nov 26","Shiozawa K, Maita N, Tomii K, Seto A, Goda N, Akiyama Y, Shimizu T, Shirakawa M, Hiroaki H"
< "Q5BL07-1","15502339","Crystallographic characterization of the N-terminal domain of PEX1.","Acta crystallographica. Section D, Biological crystallography","2004 Nov","Shiozawa K, Maita N, Tomii K, Seto A, Goda N, Akiyama Y, Shimizu T, Shirakawa M, Hiroaki H"
---
> "Q9Z148-1","30455462","Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours.","Nature cell biology","2018 Dec","Avgustinova A, Symeonidi A, Castellanos A, Urdiroz-Urricelqui U, Sole-Boldo L, Martin M, Perez-Rodriguez I, Prats N, Lehner B, Supek F, Benitah SA"
> "Q9Z148-1","29720423","Cutting Edge: The Histone Methyltransferase G9a Is Required for Silencing of Helper T Lineage-Associated Genes in Proliferating CD8 T Cells.","Journal of immunology (Baltimore, Md. : 1950)","2018 Jun 15","Verbaro DJ, Sakurai N, Kim B, Shinkai Y, Egawa T"
> "Q9Z148-1","29745895","G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst.","eLife","2018 May 10","Zylicz JJ, Borensztein M, Wong FC, Huang Y, Lee C, Dietmann S, Surani MA"
> "Q9Z148-1","29774081","G9a stimulates CRC growth by inducing p53 Lys373 dimethylation-dependent activation of Plk1.","Theranostics","2018","Zhang J, Wang Y, Shen Y, He P, Ding J, Chen Y"
> "Q9Z148-1","12586828","Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center.","The Journal of biological chemistry","2003 Apr 25","Xin Z, Tachibana M, Guggiari M, Heard E, Shinkai Y, Wagstaff J"
> "Q9Z148-1","12130538","G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.","Genes &amp; development","2002 Jul 15","Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y"
4272a4654
> "P70444-1","30281024","Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study.","eLife","2018 Oct 3","Salisbury-Ruf CT, Bertram CC, Vergeade A, Lark DS, Shi Q, Heberling ML, Fortune NL, Okoye GD, Jerome WG, Wells QS, Fessel J, Moslehi J, Chen H, Roberts LJ 2nd, Boutaud O, Gamazon ER, Zinkel SS"
4278a4661
> "P26618-1","27894125","Intronic polyadenylation of PDGFRalpha in resident stem cells attenuates muscle fibrosis.","Nature","2016 Dec 8","Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA"
4284,4286c4667,4668
< "Q3TB92-1","30556363","Allergy inhibitory receptor-1 inhibits autoantibody production via upregulation of apoptotic debris clearance by macrophages.","International journal of rheumatic diseases","2018 Dec","Iizuka A, Segawa S, Kondo Y, Kaneko S, Yokosawa M, Furuyama K, Miki H, Tahara-Hanaoka S, Shibuya A, Tsuboi H, Goto D, Matsumoto I, Shibayama S, Sumida T"
< "Q3TB92-1","27932517","Allergin-1 inhibits TLR2-mediated mast cell activation and suppresses dermatitis.","International immunology","2016 Dec","Tsurusaki S, Tahara-Hanaoka S, Shibagaki S, Miyake S, Imai M, Shibayama S, Kubo M, Shibuya A"
< "Q3TB92-1","24552759","[Immunoglobulin-like receptor, allergin-1 regulates the activation of mast cells].","Arerugi = [Allergy]","2013 Nov","Tahara-Hanaoka S, Shibuya A"
---
> "Q64338-3","30469494","Mouse Cardiac Pde1C Is a Direct Transcriptional Target of Pparalpha.","International journal of molecular sciences","2018 Nov 22","Shete V, Liu N, Jia Y, Viswakarma N, Reddy JK, Thimmapaya B"
> "Q64338-3","29860631","A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.","Human genetics","2018 Jul","Wang L, Feng Y, Yan D, Qin L, Grati M, Mittal R, Li T, Sundhari AK, Liu Y, Chapagain P, Blanton SH, Liao S, Liu X"
4289a4672,4677
> "Q91WP0-1","28739878","Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 1","Banda NK, Acharya S, Scheinman RI, Mehta G, Takahashi M, Endo Y, Zhou W, Farrar CA, Sacks SH, Fujita T, Sekine H, Holers VM"
> "Q91WP0-1","28462915","Developmental activities of the complement pathway in migrating neurons.","Nature communications","2017 May 2","Gorelik A, Sapir T, Haffner-Krausz R, Olender T, Woodruff TM, Reiner O"
> "Q91WP0-1","27235854","Experimentally-induced anti-myeloperoxidase vasculitis does not require properdin, MASP-2 or bone marrow-derived C5.","The Journal of pathology","2016 Sep","Freeley SJ, Popat RJ, Parmar K, Kolev M, Hunt BJ, Stover CM, Schwaeble W, Kemper C, Robson MG"
> "Q91WP0-1","27577570","Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.","Journal of neuroinflammation","2016 Aug 30","Orsini F, Chrysanthou E, Dudler T, Cummings WJ, Takahashi M, Fujita T, Demopulos G, De Simoni MG, Schwaeble W"
> "Q91WP0-1","15826378","Production and purification of recombinants of mouse MASP-2 and sMAP.","Journal of endotoxin research","2005","Iwaki D, Fujita T"
> "Q91WP0-1","15672593","Organization of the MASP2 locus and its expression profile in mouse and rat.","Mammalian genome : official journal of the International Mammalian Genome Society","2004 Nov","Stover CM, Lynch NJ, Hanson SJ, Windbichler M, Gregory SG, Schwaeble WJ"
4292,4294d4679
< "Q6ZQM0-1","24114843","Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation.","The Journal of biological chemistry","2013 Nov 22","Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D"
< "Q6ZQM0-1","19138581","CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.","Current biology : CB","2009 Jan 13","Ahmed AU, Moulin M, Coumailleau F, Wong WW, Miasari M, Carter H, Silke J, Cohen-Tannoudji M, Vince JE, Vaux DL"
< "Q6ZQM0-1","15229288","Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.","Molecular biology of the cell","2004 Oct","Coumailleau F, Das V, Alcover A, Raposo G, Vandormael-Pournin S, Le Bras S, Baldacci P, Dautry-Varsat A, Babinet C, Cohen-Tannoudji M"
4297,4299d4681
< "Q91XW8-1","22902560","A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.","Molecular cell","2012 Sep 28","Xiol J, Cora E, Koglgruber R, Chuma S, Subramanian S, Hosokawa M, Reuter M, Yang Z, Berninger P, Palencia A, Benes V, Penninger J, Sachidanandam R, Pillai RS"
< "Q91XW8-1","18408354","Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency.","The Journal of reproduction and development","2008 Jun","Noguchi J, Ozawa M, Nakai M, Somfai T, Kikuchi K, Kaneko H, Kunieda T"
< "Q91XW8-1","12764197","Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.","Science (New York, N.Y.)","2003 May 23","Crackower MA, Kolas NK, Noguchi J, Sarao R, Kikuchi K, Kaneko H, Kobayashi E, Kawai Y, Kozieradzki I, Landers R, Mo R, Hui CC, Nieves E, Cohen PE, Osborne LR, Wada T, Kunieda T, Moens PB, Penninger JM"
4308a4691,4695
> "Q60604-1","28389691","Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism.","Calcified tissue international","2017 Aug","Cao Y, Wang Y, Sprangers S, Picavet DI, Glogauer M, McCulloch CA, Everts V"
> "Q60604-1","26642432","Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1.","Experimental &amp; molecular medicine","2015 Dec 18","Song MK, Lee ZH, Kim HH"
> "Q60604-1","25681458","Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2015 Jun","Jiang H, Wang Y, Viniegra A, Sima C, McCulloch CA, Glogauer M"
> "Q60604-1","25275604","The actin binding protein adseverin regulates osteoclastogenesis.","PloS one","2014","Hassanpour S, Jiang H, Wang Y, Kuiper JW, Glogauer M"
> "Q60604-1","11883943","Dioxin-induced adseverin expression in the mouse thymus is strictly regulated and dependent on the aryl hydrocarbon receptor.","Biochemical and biophysical research communications","2002 Mar 15","Svensson C, Silverstone AE, Lai ZW, Lundberg K"
4313a4701,4702
> "Q921F2-1","30464263","TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle.","Nature","2018 Nov","Vogler TO, Wheeler JR, Nguyen ED, Hughes MP, Britson KA, Lester E, Rao B, Betta ND, Whitney ON, Ewachiw TE, Gomes E, Shorter J, Lloyd TE, Eisenberg DS, Taylor JP, Johnson AM, Olwin BB, Parker R"
> "Q80VL1-1","29118143","Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.","Proceedings of the National Academy of Sciences of the United States of America","2017 Nov 21","Zhang H, Liu K, Izumi N, Huang H, Ding D, Ni Z, Sidhu SS, Chen C, Tomari Y, Min J"
4315a4705,4706
> "Q61200-1","12141453","Expression of neurexin ligands, the neuroligins and the neurexophilins, in the developing and adult rodent olfactory bulb.","The International journal of developmental biology","2002","Clarris HJ, McKeown S, Key B"
> "Q8BH82-1","16818490","Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway.","The Journal of biological chemistry","2006 Sep 8","Simon GM, Cravatt BF"
4321,4324c4712
< "Q8BKH7-1","28692058","Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma.","Oncogene","2017 Nov 9","Wang Q, Zhu J, Wang YW, Dai Y, Wang YL, Wang C, Liu J, Baker A, Colburn NH, Yang HS"
< "Q8BKH7-1","28174303","Central Regulatory Role for SIN1 in Interferon gamma (IFNgamma) Signaling and Generation of Biological Responses.","The Journal of biological chemistry","2017 Mar 17","Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EN, Platanias LC"
< "Q8BKH7-1","17043309","Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.","Genes &amp; development","2006 Oct 15","Yang Q, Inoki K, Ikenoue T, Guan KL"
< "Q8BKH7-1","16962653","SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.","Cell","2006 Oct 6","Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B"
---
> "Q91ZP3-1","29765047","Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.","Nature communications","2018 May 15","Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC"
4335,4337d4722
< "Q3UMB5-1","29950492","The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis.","Genes &amp; development","2018 Jul 1","Zhang Y, Burberry A, Wang JY, Sandoe J, Ghosh S, Udeshi ND, Svinkina T, Mordes DA, Mok J, Charlton M, Li QZ, Carr SA, Eggan K"
< "Q3UMB5-1","27875531","Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.","PLoS genetics","2016 Nov","Ugolino J, Ji YJ, Conchina K, Chu J, Nirujogi RS, Pandey A, Brady NR, Hamacher-Brady A, Wang J"
< "Q3UMB5-1","27617292","A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.","Science advances","2016 Sep","Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, Chen JF"
4346a4732,4733
> "Q9JLV2-1","29704259","TRUSS Exacerbates NAFLD Development by Promoting IkappaBalpha Degradation in Mice.","Hepatology (Baltimore, Md.)","2018 Nov","Yu CJ, Wang QS, Wu MM, Song BL, Liang C, Lou J, Tang LL, Yu XD, Niu N, Yang X, Zhang BL, Qu Y, Liu Y, Dong ZC, Zhang ZR"
> "Q9JLV2-1","14585990","TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB.","Molecular and cellular biology","2003 Nov","Soond SM, Terry JL, Colbert JD, Riches DW"
4348,4350d4734
< "Q8C5N3-1","28250049","Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22.","Disease models &amp; mechanisms","2017 Mar 1","Kobayashi M, Chandrasekhar A, Cheng C, Martinez JA, Ng H, de la Hoz C, Zochodne DW"
< "Q8C5N3-1","27371833","The Evolutionary Fates of a Large Segmental Duplication in Mouse.","Genetics","2016 Sep","Morgan AP, Holt JM, McMullan RC, Bell TA, Clayshulte AM, Didion JP, Yadgary L, Thybert D, Odom DT, Flicek P, McMillan L, de Villena FP"
< "Q8C5N3-1","26149421","Divergence patterns of genic copy number variation in natural populations of the house mouse (Mus musculus domesticus) reveal three conserved genes with major population-specific expansions.","Genome research","2015 Aug","Pezer Z, Harr B, Teschke M, Babiker H, Tautz D"
4352,4357d4735
< "P23708-1","29530977","Regulation of hepatic gluconeogenesis by nuclear factor Y transcription factor in mice.","The Journal of biological chemistry","2018 May 18","Zhang Y, Guan Q, Liu Y, Zhang Y, Chen Y, Chen J, Liu Y, Su Z"
< "P23708-1","28281280","A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.","FEBS letters","2017 Apr","Nishi-Tatsumi M, Yahagi N, Takeuchi Y, Toya N, Takarada A, Murayama Y, Aita Y, Sawada Y, Piao X, Oya Y, Shikama A, Masuda Y, Kubota M, Izumida Y, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Kawakami Y, Kadowaki T, Yamada N, Shimano H"
< "P23708-1","27837431","Obesity-induced endoplasmic reticulum stress suppresses nuclear factor-Y expression.","Molecular and cellular biochemistry","2017 Feb","Liu Y, Zhang Y, Zhang Y, Zhang J, Liu Y, Feng P, Su Z"
< "Q8BG87-1","30979904","TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn.","Nature communications","2019 Apr 12","Montalban-Loro R, Lozano-Urena A, Ito M, Krueger C, Reik W, Ferguson-Smith AC, Ferron SR"
< "Q8BG87-1","30575719","A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset.","Nature communications","2018 Dec 21","Selimoglu-Buet D, Riviere J, Ghamlouch H, Bencheikh L, Lacout C, Morabito M, Diop M, Meurice G, Breckler M, Chauveau A, Debord C, Debeurme F, Itzykson R, Chapuis N, Willekens C, Wagner-Ballon O, Bernard OA, Droin N, Solary E"
< "Q8BG87-1","20639862","Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.","Nature","2010 Aug 26","Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y"
4361,4362c4739
< "Q8BWG8-1","30144357","beta-Arrestin1 alleviates acute pancreatitis via repression of NF-kappaBp65 activation.","Journal of gastroenterology and hepatology","2019 Jan","Tao L, Lin X, Tan S, Lei Y, Liu H, Guo Y, Zheng F, Wu B"
< "Q8BWG8-1","30591079","beta-arrestin 1 regulates beta2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.","Skeletal muscle","2018 Dec 27","Kim J, Grotegut CA, Wisler JW, Li T, Mao L, Chen M, Chen W, Rosenberg PB, Rockman HA, Lefkowitz RJ"
---
> "O88554-1","30104678","PARP2 mediates branched poly ADP-ribosylation in response to DNA damage.","Nature communications","2018 Aug 13","Chen Q, Kassab MA, Dantzer F, Yu X"
4373a4751,4755
> "Q9JL26-1","28361956","Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage.","Nature communications","2017 Mar 31","Pfisterer SG, Gateva G, Horvath P, Pirhonen J, Salo VT, Karhinen L, Varjosalo M, Ryhanen SJ, Lappalainen P, Ikonen E"
> "Q9JL26-1","25447542","Formin mDia1, a downstream molecule of FMNL1, regulates Profilin1 for actin assembly and spindle organization during mouse oocyte meiosis.","Biochimica et biophysica acta","2015 Feb","Zhang Y, Wang F, Niu YJ, Liu HL, Rui R, Cui XS, Kim NH, Sun SC"
> "Q9JL26-1","26083584","RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.","Cell cycle (Georgetown, Tex.)","2015","Wang F, Zhang L, Duan X, Zhang GL, Wang ZB, Wang Q, Xiong B, Sun SC"
> "Q9JL26-1","16556604","Mechanistic differences in actin bundling activity of two mammalian formins, FRL1 and mDia2.","The Journal of biological chemistry","2006 May 19","Harris ES, Rouiller I, Hanein D, Higgs HN"
> "Q9JL26-1","16480715","Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.","Experimental cell research","2006 Apr 15","Zhou F, Leder P, Martin SS"
4392a4775
> "P70188-1","16298999","Role of the kinesin-2 family protein, KIF3, during mitosis.","The Journal of biological chemistry","2006 Feb 17","Haraguchi K, Hayashi T, Jimbo T, Yamamoto T, Akiyama T"
4395a4779,4781
> "P79621-1","30165873","Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease.","Journal of neuroinflammation","2018 Aug 30","Williams GP, Schonhoff AM, Jurkuvenaite A, Thome AD, Standaert DG, Harms AS"
> "P79621-1","29238041","FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages.","Oncogene","2018 Mar","Yang JB, Zhao ZB, Liu QZ, Hu TD, Long J, Yan K, Lian ZX"
> "P79621-1","28608405","Revisiting the specificity of the MHC class II transactivator CIITA in classical murine dendritic cells in vivo.","European journal of immunology","2017 Aug","Anderson DA 3rd, Grajales-Reyes GE, Satpathy AT, Vasquez Hueichucura CE, Murphy TL, Murphy KM"
4397,4398c4783,4786
< "Q8CIV3-1","23677168","Enpp2/Autotaxin in dermal papilla precursors is dispensable for hair follicle morphogenesis.","The Journal of investigative dermatology","2013 Oct","Grisanti L, Rezza A, Clavel C, Sennett R, Rendl M"
< "P43404-1","29980684","Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.","Nature communications","2018 Jul 6","Zhao M, Svensson MND, Venken K, Chawla A, Liang S, Engel I, Mydel P, Day J, Elewaut D, Bottini N, Kronenberg M"
---
> "Q9D752-1","22700975","Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa.","The Journal of biological chemistry","2012 Jul 27","Wojtaszek J, Liu J, D'Souza S, Wang S, Xue Y, Walker GC, Zhou P"
> "Q8CHI8-1","23064015","The p400/Brd8 chromatin remodeling complex promotes adipogenesis by incorporating histone variant H2A.Z at PPARgamma target genes.","Endocrinology","2012 Dec","Couture JP, Nolet G, Beaulieu E, Blouin R, Gevry N"
> "Q8CEC0-1","18621024","Tumor marker nucleoporin 88 kDa regulates nucleocytoplasmic transport of NF-kappaB.","Biochemical and biophysical research communications","2008 Sep 26","Takahashi N, van Kilsdonk JW, Ostendorf B, Smeets R, Bruggeman SW, Alonso A, van de Loo F, Schneider M, van den Berg WB, Swart GW"
> "Q8CEC0-1","18606815","Nucleoporin 88 (Nup88) is regulated by hypertonic stress in kidney cells to retain the transcription factor tonicity enhancer-binding protein (TonEBP) in the nucleus.","The Journal of biological chemistry","2008 Sep 5","Andres-Hernando A, Lanaspa MA, Rivard CJ, Berl T"
4401,4409c4789,4792
< "Q9Z0Z4-1","30060949","Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.","Biochemical and biophysical research communications","2018 Sep 10","Xu E, Chen M, Zheng J, Maimaitiming Z, Zhong T, Chen H"
< "Q9Z0Z4-1","29883959","Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.","Redox biology","2018 Jul","Chen M, Zheng J, Liu G, Xu E, Wang J, Fuqua BK, Vulpe CD, Anderson GJ, Chen H"
< "Q9Z0Z4-1","30182051","Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin.","Cellular and molecular gastroenterology and hepatology","2018","Fuqua BK, Lu Y, Frazer DM, Darshan D, Wilkins SJ, Dunn L, Loguinov AV, Kogan SC, Matak P, Chen H, Dunaief JL, Vulpe CD, Anderson GJ"
< "Q9Z0Z4-1","29355933","Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.","FEBS letters","2018 Feb","Zheng J, Chen M, Liu G, Xu E, Chen H"
< "A2AP18-1","23237262","Phospholipase C-eta2 is required for retinoic acid-stimulated neurite growth.","Journal of neurochemistry","2013 Mar","Popovics P, Gray A, Arastoo M, Finelli DK, Tan AJ, Stewart AJ"
< "A2AP18-1","20060933","Phospholipase C-eta2 is highly expressed in the habenula and retina.","Gene expression patterns : GEP","2010 Feb-Mar","Kanemaru K, Nakahara M, Nakamura Y, Hashiguchi Y, Kouchi Z, Yamaguchi H, Oshima N, Kiyonari H, Fukami K"
< "A2AP18-1","16107206","Molecular cloning and characterization of PLC-eta2.","The Biochemical journal","2005 Nov 1","Zhou Y, Wing MR, Sondek J, Harden TK"
< "A2AP18-1","15899900","A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme.","The Journal of biological chemistry","2005 Aug 12","Nakahara M, Shimozawa M, Nakamura Y, Irino Y, Morita M, Kudo Y, Fukami K"
< "A2AP18-1","15583837","Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes.","International journal of molecular medicine","2005 Jan","Stewart AJ, Mukherjee J, Roberts SJ, Lester D, Farquharson C"
---
> "Q61107-1","29128363","GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.","Biochemical and biophysical research communications","2018 Jan 1","Xu H, Sun L, Zheng Y, Yu S, Ou-Yang J, Han H, Dai X, Yu X, Li M, Lan Q"
> "Q7TQ07-1","12794064","POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308.","The Journal of biological chemistry","2003 Aug 22","Marini F, Kim N, Schuffert A, Wood RD"
> "P48381-1","16930429","A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells.","The European journal of neuroscience","2006 Aug","Baas D, Meiniel A, Benadiba C, Bonnafe E, Meiniel O, Reith W, Durand B"
> "P48381-1","15121860","The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification.","Molecular and cellular biology","2004 May","Bonnafe E, Touka M, AitLounis A, Baas D, Barras E, Ucla C, Moreau A, Flamant F, Dubruille R, Couble P, Collignon J, Durand B, Reith W"
4417a4801,4802
> "Q8BXA0-1","27225731","SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development.","Scientific reports","2016 May 26","Choi Y, Nam J, Whitcomb DJ, Song YS, Kim D, Jeon S, Um JW, Lee SG, Woo J, Kwon SK, Li Y, Mah W, Kim HM, Ko J, Cho K, Kim E"
> "Q8BXA0-1","27152329","Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM.","Science advances","2016 Apr","Zhu Y, Yao S, Augustine MM, Xu H, Wang J, Sun J, Broadwater M, Ruff W, Luo L, Zhu G, Tamada K, Chen L"
4418a4804,4814
> "Q9D2Y4-1","30738250","MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.","Molecular immunology","2019 Mar","Zhang J, Qin D, Yang YJ, Hu GQ, Qin XX, Du CT, Chen W"
> "Q9D2Y4-1","23835476","Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.","Cell research","2013 Aug","Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y, Ma J, Chen W, Zhang Y, Zhou X, Yang Z, Wu SQ, Chen L, Han J"
> "Q9D2Y4-1","23612963","Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling.","The Journal of biological chemistry","2013 Jun 7","Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J"
> "Q9D2Y4-1","22265413","Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.","Cell","2012 Jan 20","Sun L, Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W, Lei X, Wang X"
> "P50247-1","26687445","H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase.","Nature communications","2015 Dec 21","Zhou J, Yang L, Zhong T, Mueller M, Men Y, Zhang N, Xie J, Giang K, Chung H, Sun X, Lu L, Carmichael GG, Taylor HS, Huang Y"
> "Q8CHG5-1","27162139","Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4.","The Journal of experimental medicine","2016 May 30","Lear T, McKelvey AC, Rajbhandari S, Dunn SR, Coon TA, Connelly W, Zhao JY, Kass DJ, Zhang Y, Liu Y, Chen BB"
> "Q9Z1T6-2","30295876","PIKfyve accelerates phagosome acidification through activation of TRPML1 while arrests aberrant vacuolation independent of the Ca2+ channel.","Journal of biochemistry","2019 Jan 1","Isobe Y, Nigorikawa K, Tsurumi G, Takemasu S, Takasuga S, Kofuji S, Hazeki K"
> "Q9Z1T6-2","29584722","PIKfyve regulates melanosome biogenesis.","PLoS genetics","2018 Mar","Liggins MC, Flesher JL, Jahid S, Vasudeva P, Eby V, Takasuga S, Sasaki J, Sasaki T, Boissy RE, Ganesan AK"
> "Q9Z1T6-2","28779020","The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 15","Dayam RM, Sun CX, Choy CH, Mancuso G, Glogauer M, Botelho RJ"
> "Q9Z1T6-2","28533230","Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.","The EMBO journal","2017 Jun 14","Kawasaki T, Ito K, Miyata H, Akira S, Kawai T"
> "Q9Z1T6-2","28396567","Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice.","EMBO molecular medicine","2017 Jun","Tronchere H, Cinato M, Timotin A, Guitou L, Villedieu C, Thibault H, Baetz D, Payrastre B, Valet P, Parini A, Kunduzova O, Boal F"
4425,4426c4821
< "Q8R104-1","17923681","Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.","Molecular and cellular biology","2007 Dec","Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weissman S, Verdin E, Schwer B"
< "Q8R104-1","15653680","SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes.","The Journal of biological chemistry","2005 Apr 8","Shi T, Wang F, Stieren E, Tong Q"
---
> "Q3V188-1","24344237","EndoU is a novel regulator of AICD during peripheral B cell selection.","The Journal of experimental medicine","2014 Jan 13","Poe JC, Kountikov EI, Lykken JM, Natarajan A, Marchuk DA, Tedder TF"
4448a4844,4849
> "Q99NF2-1","26977770","A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis.","PLoS genetics","2016 Mar","Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, Yuanxiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bar J, D'Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl FW, Stork O, Zenclussen AC, Karpova A, Schwegler H, Kreutz MR"
> "Q99NF2-1","25731822","NELF knockout is associated with impaired pubertal development and subfertility.","Molecular and cellular endocrinology","2015 May 15","Quaynor SD, Ko EK, Chorich LP, Sullivan ME, Demir D, Waller JL, Kim HG, Cameron RS, Layman LC"
> "Q99NF2-1","24656816","Negative elongation factor controls energy homeostasis in cardiomyocytes.","Cell reports","2014 Apr 10","Pan H, Qin K, Guo Z, Ma Y, April C, Gao X, Andrews TG, Bokov A, Zhang J, Chen Y, Weintraub ST, Fan JB, Wang D, Hu Y, Aune GJ, Lindsey ML, Li R"
> "Q99NF2-1","24316376","Differential expression of nasal embryonic LHRH factor (NELF) variants in immortalized GnRH neuronal cell lines.","Molecular and cellular endocrinology","2014 Mar 5","Quaynor SD, Goldberg LY, Ko EK, Stanley RK, Demir D, Kim HG, Chorich LP, Cameron RS, Layman LC"
> "Q99NF2-1","24317321","When synaptic proteins meet the genome: transcriptional regulation in cell death and plasticity by the synapto-nuclear messenger Jacob.","Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","2014 Jan","Bera S, Kreutz MR"
> "Q99NF2-1","19608740","Dendritic mRNA targeting of Jacob and N-methyl-d-aspartate-induced nuclear translocation after calpain-mediated proteolysis.","The Journal of biological chemistry","2009 Sep 11","Kindler S, Dieterich DC, Schutt J, Sahin J, Karpova A, Mikhaylova M, Schob C, Gundelfinger ED, Kreienkamp HJ, Kreutz MR"
4449a4851,4852
> "P97926-1","30106994","Oxytocin receptor is regulated by Peg3.","PloS one","2018","Frey WD, Sharma K, Cain TL, Nishimori K, Teruyama R, Kim J"
> "Q69ZA1-1","24999027","Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.","Experimental neurology","2014 Nov","Chen HR, Lin GT, Huang CK, Fann MJ"
4456,4457c4859,4860
< "Q9D3A9-1","28607172","Tweety-Homolog 1 Drives Brain Colonization of Gliomas.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Jul 19","Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, Solecki G, Deumelandt K, Kurz FT, Xie R, Weil S, Heil O, Thome C, Gommel M, Syed M, Haring P, Huber PE, Heiland S, Platten M, von Deimling A, Wick W, Winkler F"
< "Q9D3A9-1","20568244","Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development.","Developmental dynamics : an official publication of the American Association of Anatomists","2010 Aug","Kumada T, Yamanaka Y, Kitano A, Shibata M, Awaya T, Kato T, Okawa K, Abe T, Oshima N, Nakahata T, Heike T"
---
> "P97797-1","30770827","A functional subset of CD8(+) T cells during chronic exhaustion is defined by SIRPalpha expression.","Nature communications","2019 Feb 15","Myers LM, Tal MC, Torrez Dulgeroff LB, Carmody AB, Messer RJ, Gulati G, Yiu YY, Staron MM, Angel CL, Sinha R, Markovic M, Pham EA, Fram B, Ahmed A, Newman AM, Glenn JS, Davis MM, Kaech SM, Weissman IL, Hasenkrug KJ"
> "P97797-1","30602457","Microglia are effector cells of CD47-SIRPalpha antiphagocytic axis disruption against glioblastoma.","Proceedings of the National Academy of Sciences of the United States of America","2019 Jan 15","Hutter G, Theruvath J, Graef CM, Zhang M, Schoen MK, Manz EM, Bennett ML, Olson A, Azad TD, Sinha R, Chan C, Assad Kahn S, Gholamin S, Wilson C, Grant G, He J, Weissman IL, Mitra SS, Cheshier SH"
4459a4863,4864
> "Q69ZW3-1","15247266","Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.","The Journal of biological chemistry","2004 Sep 17","Guilherme A, Soriano NA, Furcinitti PS, Czech MP"
> "Q69ZW3-1","14676205","EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.","The Journal of biological chemistry","2004 Mar 12","Guilherme A, Soriano NA, Bose S, Holik J, Bose A, Pomerleau DP, Furcinitti P, Leszyk J, Corvera S, Czech MP"
4460a4866
> "Q62120-1","30662340","Lipopolysaccharide promoted proliferation and adipogenesis of preadipocytes through JAK/STAT and AMPK-regulated cPLA2 expression.","International journal of medical sciences","2019","Chang CC, Sia KC, Chang JF, Lin CM, Yang CM, Huang KY, Lin WN"
4463a4870,4871
> "P38532-1","30316516","NRF2 and HSF1 coordinately regulate heme oxygenase-1 expression.","Biochemical and biophysical research communications","2018 Nov 17","Inouye S, Hatori Y, Kubo T, Saito S, Kitamura H, Akagi R"
> "P38532-1","24855652","Novel isoforms of heat shock transcription factor 1, HSF1gammaalpha and HSF1gammabeta, regulate chaperone protein gene transcription.","The Journal of biological chemistry","2014 Jul 18","Neueder A, Achilli F, Moussaoui S, Bates GP"
4467a4876
> "Q6EAL8-1","29796691","Atopic Dermatitis Linked Cytokine Interleukin-31 Induced Itch Mediated via a Neuropeptide Natriuretic Polypeptide B.","Acta dermato-venereologica","2018 Aug 29","Pitake S, Ralph PC, DeBrecht J, Mishra SK"
4469a4879
> "Q8CGA0-1","29054677","Expression of the PPM1F Gene Is Regulated by Stress and Associated With Anxiety and Depression.","Biological psychiatry","2018 Feb 1","Wingo AP, Velasco ER, Florido A, Lori A, Choi DC, Jovanovic T, Ressler KJ, Andero R"
4471,4473d4880
< "Q3TDN0-1","18395198","Disp1 regulates growth of mammalian long bones through the control of Ihh distribution.","Developmental biology","2008 May 15","Tsiairis CD, McMahon AP"
< "Q3TDN0-1","12421714","Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling.","Development (Cambridge, England)","2002 Dec","Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT"
< "Q3TDN0-1","12372258","Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.","Current biology : CB","2002 Sep 17","Caspary T, Garcia-Garcia MJ, Huangfu D, Eggenschwiler JT, Wyler MR, Rakeman AS, Alcorn HL, Anderson KV"
4480,4481d4886
< "Q9WUH2-3","29565736","Smad ubiquitylation regulatory factor 1 promotes LIM-homeobox gene 9 degradation and represses testosterone production in Leydig cells.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Sep","Hu F, Zhu Q, Sun B, Cui C, Li C, Zhang L"
< "Q9WUH2-3","28456934","Lhx9 Is Required for the Development of Retinal Nitric Oxide-Synthesizing Amacrine Cell Subtype.","Molecular neurobiology","2018 Apr","Balasubramanian R, Bui A, Dong X, Gan L"
4484a4890,4894
> "Q3TEA8-1","27460150","Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.","Neurobiology of aging","2016 Oct","Neuner SM, Garfinkel BP, Wilmott LA, Ignatowska-Jankowska BM, Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O'Connell KM, Kaczorowski CC"
> "Q3TEA8-1","27470444","HP1BP3 expression determines maternal behavior and offspring survival.","Genes, brain, and behavior","2016 Sep","Garfinkel BP, Arad S, Neuner SM, Netser S, Wagner S, Kaczorowski CC, Rosen CJ, Gal M, Soreq H, Orly J"
> "Q3TEA8-1","26976970","Heterochromatin Protein 1 Binding Protein 3 Expression as a Candidate Marker of Intrinsic 5-Fluorouracil Resistance.","Anticancer research","2016 Mar","Hadac JN, Miller DD, Grimes IC, Clipson L, Newton MA, Schelman WR, Halberg RB"
> "Q3TEA8-1","26402843","Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.","Endocrinology","2015 Dec","Garfinkel BP, Arad S, Le PT, Bustin M, Rosen CJ, Gabet Y, Orly J"
> "Q3TEA8-1","25662603","HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth.","Nucleic acids research","2015 Feb 27","Garfinkel BP, Melamed-Book N, Anuka E, Bustin M, Orly J"
4497,4498d4906
< "Q8CI08-1","23077057","Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote axonal development.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2012 Oct 17","van der Vaart B, Franker MA, Kuijpers M, Hua S, Bouchet BP, Jiang K, Grigoriev I, Hoogenraad CC, Akhmanova A"
< "Q8CI08-1","21646404","SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase.","The Journal of cell biology","2011 Jun 13","van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A"
4515c4923,4925
< "Q61419-1","29196263","Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute.","Biochemical and biophysical research communications","2018 Jan 1","Bousquet PA, Sandvik JA, Jeppesen Edin NF, Krengel U"
---
> "Q8K371-1","17397395","Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2007 Apr","Sugihara-Mizuno Y, Adachi M, Kobayashi Y, Hamazaki Y, Nishimura M, Imai T, Furuse M, Tsukita S"
> "Q14BT6-1","10430883","Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1--&gt;4Galbeta--&gt;R, a glycan specifically expressed in the gastric gland mucous cell-type mucin.","Proceedings of the National Academy of Sciences of the United States of America","1999 Aug 3","Nakayama J, Yeh JC, Misra AK, Ito S, Katsuyama T, Fukuda M"
> "Q80VP5-1","22821833","Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65.","Proteins","2012 Nov","Kogure H, Hikawa Y, Hagihara M, Tochio N, Koshiba S, Inoue Y, Guntert P, Kigawa T, Yokoyama S, Nameki N"
4517,4518c4927,4928
< "Q8CGF7-1","21365688","The ensemble folding kinetics of the FBP28 WW domain revealed by an all-atom Monte Carlo simulation in a knowledge-based potential.","Proteins","2011 Jun","Xu J, Huang L, Shakhnovich EI"
< "Q8CGF7-1","16784750","Phi-analysis at the experimental limits: mechanism of beta-hairpin formation.","Journal of molecular biology","2006 Jul 21","Petrovich M, Jonsson AL, Ferguson N, Daggett V, Fersht AR"
---
> "Q9EQZ6-1","30048476","Deletion of exchange proteins directly activated by cAMP (Epac) causes defects in hippocampal signaling in female mice.","PloS one","2018","Aesoy R, Muwonge H, Asrud KS, Sabir M, Witsoe SL, Bjornstad R, Kopperud RK, Hoivik EA, Doskeland SO, Bakke M"
> "Q9EQZ6-1","12401793","Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis.","The Journal of biological chemistry","2002 Dec 27","Fujimoto K, Shibasaki T, Yokoi N, Kashima Y, Matsumoto M, Sasaki T, Tajima N, Iwanaga T, Seino S"
4534,4537d4943
< "Q9WTP6-1","24740601","Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm.","Biology of reproduction","2014 Jun","Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL"
< "Q9WTP6-1","24548998","The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth.","Nature communications","2014","Kim H, Lee HJ, Oh Y, Choi SG, Hong SH, Kim HJ, Lee SY, Choi JW, Su Hwang D, Kim KS, Kim HJ, Zhang J, Youn HJ, Noh DY, Jung YK"
< "Q9WTP6-1","20876536","Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response.","The Journal of biological chemistry","2011 Feb 11","Burkart A, Shi X, Chouinard M, Corvera S"
< "Q9WTP6-1","20728450","Akt2 deficiency promotes cardiac induction of Rab4a and myocardial beta-adrenergic hypersensitivity.","Journal of molecular and cellular cardiology","2010 Dec","Etzion S, Etzion Y, DeBosch B, Crawford PA, Muslin AJ"
4541a4948
> "P98078-1","30275566","Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease.","Nature medicine","2018 Nov","Qiu C, Huang S, Park J, Park Y, Ko YA, Seasock MJ, Bryer JS, Xu XX, Song WC, Palmer M, Hill J, Guarnieri P, Hawkins J, Boustany-Kari CM, Pullen SS, Brown CD, Susztak K"
4545a4953
> "Q9WTN0-1","21224049","Cigarette smoke-induced pulmonary inflammatory responses are mediated by EGR-1/GGPPS/MAPK signaling.","The American journal of pathology","2011 Jan","Shen N, Gong T, Wang JD, Meng FL, Qiao L, Yang RL, Xue B, Pan FY, Zhou XJ, Chen HQ, Ning W, Li CJ"
4548a4957,4961
> "Q920R0-1","27439389","Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.","Human molecular genetics","2016 Aug 1","Hadano S, Mitsui S, Pan L, Otomo A, Kubo M, Sato K, Ono S, Onodera W, Abe K, Chen X, Koike M, Uchiyama Y, Aoki M, Warabi E, Yamamoto M, Ishii T, Yanagawa T, Shang HF, Yoshii F"
> "Q920R0-1","26755825","Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms.","Human molecular genetics","2016 Mar 15","Gautam M, Jara JH, Sekerkova G, Yasvoina MV, Martina M, Ozdinler PH"
> "Q920R0-1","22982304","Are alsin and spartin novel interaction partners?","Biochemical and biophysical research communications","2012 Oct 12","Cobanoglu G, Ozansoy M, Basak AN"
> "Q920R0-1","21937428","Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity.","The Journal of biological chemistry","2011 Nov 18","Li Q, Spencer NY, Pantazis NJ, Engelhardt JF"
> "Q99P30-1","18799520","The nudix hydrolase 7 is an Acyl-CoA diphosphatase involved in regulating peroxisomal coenzyme A homeostasis.","Journal of biochemistry","2008 Nov","Reilly SJ, Tillander V, Ofman R, Alexson SE, Hunt MC"
4552,4556c4965,4966
< "Q9Z1X4-1","28487382","NF45 and NF90/NF110 coordinately regulate ESC pluripotency and differentiation.","RNA (New York, N.Y.)","2017 Aug","Ye J, Jin H, Pankov A, Song JS, Blelloch R"
< "Q9Z1X4-1","26289635","Nanog RNA-binding proteins YBX1 and ILF3 affect pluripotency of embryonic stem cells.","Cell biology international","2016 Aug","Guo C, Xue Y, Yang G, Yin S, Shi W, Cheng Y, Yan X, Fan S, Zhang H, Zeng F"
< "Q9Z1X4-1","25918244","Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers.","Molecular and cellular biology","2015 Jul","Todaka H, Higuchi T, Yagyu K, Sugiyama Y, Yamaguchi F, Morisawa K, Ono M, Fukushima A, Tsuda M, Taniguchi T, Sakamoto S"
< "Q9Z1X4-1","11438536","Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR.","The Journal of biological chemistry","2001 Aug 24","Saunders LR, Perkins DJ, Balachandran S, Michaels R, Ford R, Mayeda A, Barber GN"
< "Q9Z1X4-1","7519613","Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.","The Journal of biological chemistry","1994 Aug 12","Kao PN, Chen L, Brock G, Ng J, Kenny J, Smith AJ, Corthesy B"
---
> "P48678-1","21327075","Dynamic properties of meiosis-specific lamin C2 and its impact on nuclear envelope integrity.","Nucleus (Austin, Tex.)","2010 May-Jun","Jahn D, Schramm S, Benavente R, Alsheimer M"
> "P04627-1","24114843","Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation.","The Journal of biological chemistry","2013 Nov 22","Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D"
4557a4968
> "P61237-1","21196260","Why YPEL3 represents a novel tumor suppressor.","Frontiers in bioscience (Landmark edition)","2011 Jan 1","Berberich SJ, Todd A, Tuttle R"
4575,4579d4985
< "Q8BKV0-1","25138526","Structural abnormalities of corpus callosum and cortical axonal tracts accompanied by decreased anxiety-like behavior and lowered sociability in spock3- mutant mice.","Developmental neuroscience","2014","Yamamoto A, Uchiyama K, Nara T, Nishimura N, Hayasaka M, Hanaoka K, Yamamoto T"
< "Q8BKV0-1","23418755","Testican-3: a brain-specific proteoglycan member of the BM-40/SPARC/osteonectin family.","Journal of neurochemistry","2013 May","Hartmann U, Hulsmann H, Seul J, Roll S, Midani H, Breloy I, Hechler D, Muller R, Paulsson M"
< "Q6PAM1-1","26494466","Unexpected requirement for a binding partner of the syntaxin family in phagocytosis by murine testicular Sertoli cells.","Cell death and differentiation","2016 May","Dong YS, Hou WG, Li Y, Liu DB, Hao GZ, Zhang HF, Li JC, Zhao J, Zhang S, Liang GB, Li W"
< "Q6PAM1-1","19663695","Characteristics of a novel monoclonal antibody against interleukin-14alpha.","Hybridoma (2005)","2009 Aug","Peng X, Zhou C, Wei D, Luo Z, Zhang C"
< "Q6PAM1-1","19038581","IL-14 alpha, the nexus for primary Sjogren's disease in mice and humans.","Clinical immunology (Orlando, Fla.)","2009 Mar","Shen L, Suresh L, Li H, Zhang C, Kumar V, Pankewycz O, Ambrus JL Jr"
4587a4994,4996
> "Q9QZX7-1","29913163","Loss-of-function mutation of serine racemase attenuates retinal ganglion cell loss in diabetic mice.","Experimental eye research","2018 Oct","Jiang H, Du J, Song J, Li Y, Wu M, Zhou J, Wu S"
> "Q9QZX7-1","28892569","Serine racemase deficiency attenuates choroidal neovascularization and reduces nitric oxide and VEGF levels by retinal pigment epithelial cells.","Journal of neurochemistry","2017 Nov","Jiang H, Wu M, Liu Y, Song L, Li S, Wang X, Zhang YF, Fang J, Wu S"
> "Q9QZX7-1","12021263","Direct calcium binding results in activation of brain serine racemase.","The Journal of biological chemistry","2002 Aug 2","Cook SP, Galve-Roperh I, Martinez del Pozo A, Rodriguez-Crespo I"
4589,4590d4997
< "Q9D7Q1-1","26079949","Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.","Clinical immunology (Orlando, Fla.)","2015 Oct","Canto E, Espejo C, Costa C, Montalban X, Comabella M"
< "Q9D7Q1-1","23685110","Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice.","The American journal of pathology","2013 Jul","Kitamoto S, Egashira K, Ichiki T, Han X, McCurdy S, Sakuda S, Sunagawa K, Boisvert WA"
4601a5009
> "Q8CJ70-1","28864472","The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models.","Journal of immunology (Baltimore, Md. : 1950)","2017 Oct 1","Steinert A, Linas I, Kaya B, Ibrahim M, Schlitzer A, Hruz P, Radulovic K, Terracciano L, Macpherson AJ, Niess JH"
4610a5019,5021
> "Q8K4J0-1","25818648","Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.","Molecular cell","2015 Apr 2","Jiang W, Crowe JL, Liu X, Nakajima S, Wang Y, Li C, Lee BJ, Dubois RL, Liu C, Yu X, Lan L, Zha S"
> "Q8K4J0-1","12615897","Defective DNA repair and increased genomic instability in Artemis-deficient murine cells.","The Journal of experimental medicine","2003 Mar 3","Rooney S, Alt FW, Lombard D, Whitlow S, Eckersdorff M, Fleming J, Fugmann S, Ferguson DO, Schatz DG, Sekiguchi J"
> "Q8K4J0-1","12504013","Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice.","Molecular cell","2002 Dec","Rooney S, Sekiguchi J, Zhu C, Cheng HL, Manis J, Whitlow S, DeVido J, Foy D, Chaudhuri J, Lombard D, Alt FW"
4617a5029,5031
> "Q8K1S7-1","12050670","Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.","Nature","2002 Jun 6","Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C"
> "Q9Z248-1","25451679","AEBP2 as a transcriptional activator and its role in cell migration.","Genomics","2015 Feb","Kim H, Ekram MB, Bakshi A, Kim J"
> "Q9Z248-1","19293275","AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.","Nucleic acids research","2009 May","Kim H, Kang K, Kim J"
4621,4623d5034
< "Q9QYC0-1","29032200","Sez6l2 regulates phosphorylation of ADD and neuritogenesis.","Biochemical and biophysical research communications","2017 Dec 9","Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S"
< "Q9QYC0-1","28982183","NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between alpha-Adducin and Myosin X.","PloS one","2017","Brieno-Enriquez MA, Moak SL, Holloway JK, Cohen PE"
< "Q9QYC0-1","27068466","The Actin-Binding Protein alpha-Adducin Is Required for Maintaining Axon Diameter.","Cell reports","2016 Apr 19","Leite SC, Sampaio P, Sousa VF, Nogueira-Rodrigues J, Pinto-Costa R, Peters LL, Brites P, Sousa MM"
4640c5051,5052
< "P21836-1","30076217","Microphthalmia-associated transcription factor up-regulates acetylcholinesterase expression during melanogenesis of murine melanoma cells.","The Journal of biological chemistry","2018 Sep 14","Wu Q, Fung AHY, Xu ML, Poon K, Liu EYL, Kong XP, Yao P, Xiong QP, Dong TTX, Tsim KWK"
---
> "Q9D0U6-1","26910647","MAF1 suppresses AKT-mTOR signaling and liver cancer through activation of PTEN transcription.","Hepatology (Baltimore, Md.)","2016 Jun","Li Y, Tsang CK, Wang S, Li XX, Yang Y, Fu L, Huang W, Li M, Wang HY, Zheng XF"
> "P49443-1","28911860","Glucose elicits serine/threonine kinase VRK1 to phosphorylate nuclear pregnane X receptor as a novel hepatic gluconeogenic signal.","Cellular signalling","2017 Dec","Gotoh S, Miyauchi Y, Moore R, Negishi M"
4651,4653d5062
< "Q8CGN4-1","30902969","Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis.","Nature communications","2019 Mar 22","Kelly MJ, So J, Rogers AJ, Gregory G, Li J, Zethoven M, Gearhart MD, Bardwell VJ, Johnstone RW, Vervoort SJ, Kats LM"
< "Q8CGN4-1","28827447","Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.","The Journal of experimental medicine","2017 Oct 2","Tanaka T, Nakajima-Takagi Y, Aoyama K, Tara S, Oshima M, Saraya A, Koide S, Si S, Manabe I, Sanada M, Nakayama M, Masuko M, Sone H, Koseki H, Iwama A"
< "Q8CGN4-1","28262675","Genomic characterisation of Emu-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.","Nature communications","2017 Mar 6","Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW"
4659a5069,5074
> "Q8K2F0-1","28733670","BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.","Scientific reports","2017 Jul 21","Roberts TC, Etxaniz U, Dall'Agnese A, Wu SY, Chiang CM, Brennan PE, Wood MJA, Puri PL"
> "Q8K2F0-1","27667451","[Brd3 promotes IL-6 production via enhancing acetylase CBP recruitment and histone 3 acetylation within IL6 promoter].","Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology","2016 Oct","Ren W, Sun D, Wang C, Li N"
> "Q8K2F0-1","24248598","Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.","Molecular and cellular biology","2014 Feb","Wienerroither S, Rauch I, Rosebrock F, Jamieson AM, Bradner J, Muhar M, Zuber J, Muller M, Decker T"
> "Q8K2F0-1","16008511","Differentially expressed genes in endothelial differentiation.","DNA and cell biology","2005 Jul","Ishii H, Mimori K, Mori M, Vecchione A"
> "Q8K2F0-1","15128596","Pre-sertoli specific gene expression profiling reveals differential expression of Ppt1 and Brd3 genes within the mouse genital ridge at the time of sex determination.","Biology of reproduction","2004 Sep","Boyer A, Lussier JG, Sinclair AH, McClive PJ, Silversides DW"
> "Q8C1B7-1","21824005","Lethal phenotype of mice carrying a Sept11 null mutation.","Biological chemistry","2011 Aug","Roseler S, Sandrock K, Bartsch I, Busse A, Omran H, Loges NT, Zieger B"
4661c5076,5079
< "Q8BGQ1-1","29409756","VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function.","Biochimica et biophysica acta. Molecular basis of disease","2018 May","Rogerson C, Gissen P"
---
> "P42866-1","30738575","In vitro and in vivo characterization of the bifunctional mu- and delta- opioid receptors ligand MCRT on mouse gastrointestinal motility.","Neuropeptides","2019 Apr","He C, Li H, Zhang J, Zhou L, Dong S"
> "P42866-1","30664663","Phosphorylation-deficient G-protein-biased mu-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects.","Nature communications","2019 Jan 21","Kliewer A, Schmiedel F, Sianati S, Bailey A, Bateman JT, Levitt ES, Williams JT, Christie MJ, Schulz S"
> "P42866-1","17284463","Translational repression of mouse mu opioid receptor expression via leaky scanning.","Nucleic acids research","2007","Song KY, Hwang CK, Kim CS, Choi HS, Law PY, Wei LN, Loh HH"
> "Q9D0V7-1","21573489","Intracellular estrogen receptor-binding fragment-associated antigen 9 exerts in vivo tumor-promoting effects via its coiled-coil region.","International journal of oncology","2011 Jul","Maeyama Y, Otsu M, Kubo S, Yamano T, Iimura Y, Onodera M, Kondo S, Sakiyama Y, Ariga T"
4667a5086
> "P27699-1","30228239","Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease.","mBio","2018 Sep 18","Wojcik GL, Marie C, Abhyankar MM, Yoshida N, Watanabe K, Mentzer AJ, Carstensen T, Mychaleckyj J, Kirkpatrick BD, Rich SS, Concannon P, Haque R, Tsokos GC, Petri WA Jr, Duggal P"
4672a5092
> "Q91W50-1","30138317","Strap associates with Csde1 and affects expression of select Csde1-bound transcripts.","PloS one","2018","Moore KS, Yagci N, van Alphen F, Meijer AB, 't Hoen PAC, von Lindern M"
4675a5096,5099
> "Q8VDR9-1","17196961","Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth.","Experimental cell research","2007 Feb 15","Miyamoto Y, Yamauchi J, Sanbe A, Tanoue A"
> "O88904-1","22095214","Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1.","Cerebral cortex (New York, N.Y. : 1991)","2012 Oct","Marinaro C, Pannese M, Weinandy F, Sessa A, Bergamaschi A, Taketo MM, Broccoli V, Comi G, Gotz M, Martino G, Muzio L"
> "O88904-1","22545114","Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response.","PloS one","2012","Guerra FM, Gommerman JL, Corfe SA, Paige CJ, Rottapel R"
> "O88904-1","12529400","Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.","Molecular and cellular biology","2003 Feb","Ecsedy JA, Michaelson JS, Leder P"
4682,4686d5105
< "Q8BZ98-1","28395327","Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.","Biology of reproduction","2017 Jan 1","Zhou W, De Iuliis GN, Turner AP, Reid AT, Anderson AL, McCluskey A, McLaughlin EA, Nixon B"
< "Q8BZ98-1","27251629","Dynamin 1- and 3-Mediated Endocytosis Is Essential for the Development of a Large Central Synapse In Vivo.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2016 Jun 1","Fan F, Funk L, Lou X"
< "Q8BZ98-1","24963135","A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.","eLife","2014 Jun 24","Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P"
< "Q8BZ98-1","24273169","Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting.","The Journal of biological chemistry","2014 Jan 10","Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G, Kremer EJ"
< "Q8BZ98-1","19007685","Dynamin 3 participates in the growth and development of megakaryocytes.","Experimental hematology","2008 Dec","Reems JA, Wang W, Tsubata K, Abdurrahman N, Sundell B, Tijssen MR, van der Schoot E, Di Summa F, Patel-Hett S, Italiano J Jr, Gilligan DM"
4694,4696d5112
< "Q5XJV7-1","30655503","Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice.","Translational psychiatry","2019 Jan 17","Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, Troutman TD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR"
< "Q5XJV7-1","30455454","Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition.","Nature neuroscience","2018 Dec","Deliu E, Arecco N, Morandell J, Dotter CP, Contreras X, Girardot C, Kasper EL, Kozlova A, Kishi K, Chiaradia I, Noh KM, Novarino G"
< "Q5XJV7-1","29180574","miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons.","Development (Cambridge, England)","2018 Jan 8","Villain G, Poissonnier L, Noueihed B, Bonfils G, Rivera JC, Chemtob S, Soncin F, Mattot V"
4698,4699c5114,5116
< "Q61036-1","29860311","PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.","Human molecular genetics","2018 Aug 15","Bondar VV, Adamski CJ, Onur TS, Tan Q, Wang L, Diaz-Garcia J, Park J, Orr HT, Botas J, Zoghbi HY"
< "Q61036-1","27940202","The intellectual disability protein PAK3 regulates oligodendrocyte precursor cell differentiation.","Neurobiology of disease","2017 Feb","Maglorius Renkilaraj MRL, Baudouin L, Wells CM, Doulazmi M, Wehrle R, Cannaya V, Bachelin C, Barnier JV, Jia Z, Nait Oumesmar B, Dusart I, Bouslama-Oueghlani L"
---
> "Q7TSC3-1","23727203","Nek5, a novel substrate for caspase-3, promotes skeletal muscle differentiation by up-regulating caspase activity.","FEBS letters","2013 Jul 11","Shimizu K, Sawasaki T"
> "Q91X46-1","28542600","SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume.","PloS one","2017","Zou S, Teixeira AM, Kostadima M, Astle WJ, Radhakrishnan A, Simon LM, Truman L, Fang JS, Hwa J, Zhang PX, van der Harst P, Bray PF, Ouwehand WH, Frontini M, Krause DS"
> "Q91X46-1","23192023","Structure of the Rho-specific guanine nucleotide-exchange factor Xpln.","Acta crystallographica. Section F, Structural biology and crystallization communications","2012 Dec 1","Murayama K, Kato-Murayama M, Akasaka R, Terada T, Yokoyama S, Shirouzu M"
4701a5119
> "Q921I6-1","22575674","SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.","Molecular cell","2012 Jun 29","Kim YM, Stone M, Hwang TH, Kim YG, Dunlevy JR, Griffin TJ, Kim DH"
4703,4706c5121,5125
< "Q8C7Q4-1","30327195","RBM4a modulates the impact of PRDM16 on development of brown adipocytes through an alternative splicing mechanism.","Biochimica et biophysica acta. Molecular cell research","2018 Nov","Chi YL, Lin JC"
< "Q8C7Q4-1","30200638","RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis.","International journal of molecular sciences","2018 Sep 6","Peng HY, Liang YC, Tan TH, Chuang HC, Lin YJ, Lin JC"
< "P70662-1","30873428","LDB1 Is Required for the Early Development of the Dorsal Telencephalon and the Thalamus.","eNeuro","2019 Jan-Feb","Kinare V, Pal S, Tole S"
< "P70662-1","16815859","Spliced isoforms of LIM-domain-binding protein (CLIM/NLI/Ldb) lacking the LIM-interaction domain.","Journal of biochemistry","2006 Jul","Tran YH, Xu Z, Kato A, Mistry AC, Goya Y, Taira M, Brandt SJ, Hirose S"
---
> "Q8BJS4-1","29995584","A molecular model for LINC complex regulation: activation of SUN2 for KASH binding.","Molecular biology of the cell","2018 Aug 8","Jahed Z, Vu UT, Fadavi D, Ke H, Rathish A, Kim SCJ, Feng W, Mofrad MRK"
> "Q8BJS4-1","19509342","SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.","Proceedings of the National Academy of Sciences of the United States of America","2009 Jun 23","Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M"
> "Q8BJS4-1","17452644","Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope.","Proceedings of the National Academy of Sciences of the United States of America","2007 May 1","Schmitt J, Benavente R, Hodzic D, Hoog C, Stewart CL, Alsheimer M"
> "Q8BJS4-1","17132086","Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome.","DNA and cell biology","2006 Oct","Wang Q, Du X, Cai Z, Greene MI"
> "Q9ET43-1","14698084","Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.","Hearing research","2004 Jan","Kitajiri SI, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita S"
4709,4711d5127
< "Q9Z248-1","25451679","AEBP2 as a transcriptional activator and its role in cell migration.","Genomics","2015 Feb","Kim H, Ekram MB, Bakshi A, Kim J"
< "Q9Z248-1","19293275","AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.","Nucleic acids research","2009 May","Kim H, Kang K, Kim J"
< "Q5SPX1-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
4713a5130
> "Q8VHX6-1","26929074","HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles.","Journal of cell science","2016 Apr 15","Juo LY, Liao WC, Shih YL, Yang BY, Liu AB, Yan YT"
4714a5132,5133
> "Q69Z98-1","17482548","LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.","Cell","2007 May 4","Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F"
> "Q69Z98-1","15705853","Mammalian SAD kinases are required for neuronal polarization.","Science (New York, N.Y.)","2005 Feb 11","Kishi M, Pan YA, Crump JG, Sanes JR"
4723,4724d5141
< "Q7TPD1-1","27166359","FBXO11 inactivation leads to abnormal germinal-center formation and lymphoproliferative disease.","Blood","2016 Aug 4","Schneider C, Kon N, Amadori L, Shen Q, Schwartz FH, Tischler B, Bossennec M, Dominguez-Sola D, Bhagat G, Gu W, Basso K, Dalla-Favera R"
< "Q7TPD1-1","26471094","Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.","Disease models &amp; mechanisms","2015 Dec","Tateossian H, Morse S, Simon MM, Dean CH, Brown SD"
4730a5148
> "Q07563-1","28693719","Type XVII collagen coordinates proliferation in the interfollicular epidermis.","eLife","2017 Jul 11","Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuki S, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt FM, Shimizu H"
4735a5154
> "Q8BVG8-1","19807691","Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia.","The Biochemical journal","2009 Dec 14","Wiame E, Tyteca D, Pierrot N, Collard F, Amyere M, Noel G, Desmedt J, Nassogne MC, Vikkula M, Octave JN, Vincent MF, Courtoy PJ, Boltshauser E, van Schaftingen E"
4738a5158,5159
> "Q62523-1","29967145","Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation.","Proceedings of the National Academy of Sciences of the United States of America","2018 Jul 17","Zhou J, Zeng Y, Cui L, Chen X, Stauffer S, Wang Z, Yu F, Lele SM, Talmon GA, Black AR, Chen Y, Dong J"
> "Q62523-1","28256511","Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules.","Nature communications","2017 Mar 3","Han X, Li P, Yang Z, Huang X, Wei G, Sun Y, Kang X, Hu X, Deng Q, Chen L, He A, Huo Y, Li D, Betzig E, Luo J"
4740a5162
> "Q3UJF0-1","30196316","Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.","Histochemistry and cell biology","2019 Jan","Grill M, Hasenoehrl C, Kienzl M, Kargl J, Schicho R"
4742a5165,5168
> "Q3ULW8-1","30213852","Parp3 promotes long-range end joining in murine cells.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 2","Layer JV, Cleary JP, Brown AJ, Stevenson KE, Morrow SN, Van Scoyk A, Blasco RB, Karaca E, Meng FL, Frock RL, Tivey T, Kim S, Fuchs H, Chiarle R, Alt FW, Roberts SA, Weinstock DM, Day TA"
> "Q3ULW8-1","26000965","Parp3 negatively regulates immunoglobulin class switch recombination.","PLoS genetics","2015 May","Robert I, Gaudot L, Rogier M, Heyer V, Noll A, Dantzer F, Reina-San-Martin B"
> "Q3ULW8-1","21211721","PARP-3 and APLF function together to accelerate nonhomologous end-joining.","Molecular cell","2011 Jan 7","Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW"
> "Q3ULW8-1","12448766","Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.","Folia biologica","2002","Urbanek P, Paces J, Kralova J, Dvorak M, Paces V"
4750,4754c5176,5178
< "Q8CGN5-1","30042231","Perilipin 1 (Plin1) deficiency promotes inflammatory responses in lean adipose tissue through lipid dysregulation.","The Journal of biological chemistry","2018 Sep 7","Sohn JH, Lee YK, Han JS, Jeon YG, Kim JI, Choe SS, Kim SJ, Yoo HJ, Kim JB"
< "Q8CGN5-1","29407594","Overexpression of perilipin1 protects against atheroma progression in apolipoprotein E knockout mice.","Atherosclerosis","2018 Feb","Yamamoto K, Miyoshi H, Cho KY, Nakamura A, Greenberg AS, Atsumi T"
< "Q8CGN5-1","29191637","Spontaneous development of hepatosteatosis in perilipin-1 null mice with adipose tissue dysfunction.","Biochimica et biophysica acta. Molecular and cell biology of lipids","2018 Feb","Wei S, Liu S, Su X, Wang W, Li F, Deng J, Lyu Y, Geng B, Xu G"
< "Q8CGN5-1","12407111","The central domain is required to target and anchor perilipin A to lipid droplets.","The Journal of biological chemistry","2003 Jan 3","Garcia A, Sekowski A, Subramanian V, Brasaemle DL"
< "Q8CGN5-1","11751901","Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system.","The Journal of biological chemistry","2002 Mar 8","Souza SC, Muliro KV, Liscum L, Lien P, Yamamoto MT, Schaffer JE, Dallal GE, Wang X, Kraemer FB, Obin M, Greenberg AS"
---
> "Q9ET38-1","25678664","Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin.","Science (New York, N.Y.)","2015 Feb 13","Saitoh Y, Suzuki H, Tani K, Nishikawa K, Irie K, Ogura Y, Tamura A, Tsukita S, Fujiyoshi Y"
> "Q9ET38-1","15589828","Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells.","FEBS letters","2004 Dec 17","Luk JM, Tong MK, Mok BW, Tam PC, Yeung WS, Lee KF"
> "P0DOV1-1","23145002","Apoptosis-related gene expression profiles of mouse ESCs and maGSCs: role of Fgf4 and Mnda in pluripotent cell responses to genotoxicity.","PloS one","2012","Khromov T, Dressel R, Siamishi I, Nolte J, Opitz L, Engel W, Pantakani DV"
4755a5180
> "Q9D219-1","28174279","A cytoplasmic role of Wnt/beta-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.","Science signaling","2017 Feb 7","Cantu C, Pagella P, Shajiei TD, Zimmerli D, Valenta T, Hausmann G, Basler K, Mitsiadis TA"
4756a5182
> "Q8CDP0-1","25103237","The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.","Molecular biology of the cell","2014 Oct 1","Tort O, Tanco S, Rocha C, Bieche I, Seixas C, Bosc C, Andrieux A, Moutin MJ, Aviles FX, Lorenzo J, Janke C"
4760,4761d5185
< "Q60597-1","28242228","Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex.","Free radical biology &amp; medicine","2017 May","O'Brien M, Chalker J, Slade L, Gardiner D, Mailloux RJ"
< "Q60597-1","27582470","Oncometabolite d-2-hydroxyglutarate impairs alpha-ketoglutarate dehydrogenase and contractile function in rodent heart.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 13","Karlstaedt A, Zhang X, Vitrac H, Harmancey R, Vasquez H, Wang JH, Goodell MA, Taegtmeyer H"
4767,4772d5190
< "Q8R1G6-1","29852170","Suppression of NF-kappaB activation by PDLIM2 restrains hepatic lipogenesis and inflammation in high fat diet induced mice.","Biochemical and biophysical research communications","2018 Sep 5","Hao YR, Tang FJ, Zhang X, Wang H"
< "Q8R1G6-1","28315683","Klotho ameliorates cyclosporine A-induced nephropathy via PDLIM2/NF-kB p65 signaling pathway.","Biochemical and biophysical research communications","2017 Apr 29","Jin M, Lv P, Chen G, Wang P, Zuo Z, Ren L, Bi J, Yang CW, Mei X, Han D"
< "Q8R1G6-1","22155789","PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3.","Science signaling","2011 Dec 6","Tanaka T, Yamamoto Y, Muromoto R, Ikeda O, Sekine Y, Grusby MJ, Kaisho T, Matsuda T"
< "Q8R1G6-1","17468759","PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit.","Nature immunology","2007 Jun","Tanaka T, Grusby MJ, Kaisho T"
< "Q8R1G6-1","15963787","SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling.","Immunity","2005 Jun","Tanaka T, Soriano MA, Grusby MJ"
< "Q8R1G6-1","15659642","Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth.","Molecular biology of the cell","2005 Apr","Loughran G, Healy NC, Kiely PA, Huigsloot M, Kedersha NL, O'Connor R"
4786,4789d5203
< "Q8K4K6-1","26549575","Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.","Molecular genetics and metabolism","2015 Dec","Zano SP, Pate C, Frank M, Rock CO, Jackowski S"
< "Q8K4K6-1","24781151","Pank1 deletion in leptin-deficient mice reduces hyperglycaemia and hyperinsulinaemia and modifies global metabolism without affecting insulin resistance.","Diabetologia","2014 Jul","Leonardi R, Rock CO, Jackowski S"
< "Q8K4K6-1","23343762","p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.","Cell cycle (Georgetown, Tex.)","2013 Mar 1","Wang SJ, Yu G, Jiang L, Li T, Lin Q, Tang Y, Gu W"
< "Q8K4K6-1","20559429","Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state.","PloS one","2010 Jun 14","Leonardi R, Rehg JE, Rock CO, Jackowski S"
4807a5222,5224
> "Q2M3X8-1","28803787","Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.","Neuroscience research","2018 Mar","Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI"
> "Q2M3X8-1","28720499","Coronary artery disease associated gene Phactr1 modulates severity of vascular calcification in vitro.","Biochemical and biophysical research communications","2017 Sep 16","Aherrahrou R, Aherrahrou Z, Schunkert H, Erdmann J"
> "Q2M3X8-1","22766235","Different expression patterns of Phactr family members in normal and injured mouse brain.","Neuroscience","2012 Sep 27","Kim JY, Choi SY, Moon Y, Kim HJ, Chin JH, Kim H, Sun W"
4818a5236,5237
> "Q8VCF1-1","28330694","CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma.","Molecular therapy : the journal of the American Society of Gene Therapy","2017 May 3","Xing Y, Wen X, Ding X, Fan J, Chai P, Jia R, Ge S, Qian G, Zhang H, Fan X"
> "Q8VCF1-1","22451650","Ca2+-activated nucleotidase 1, a novel target gene for the transcriptional repressor DREAM (downstream regulatory element antagonist modulator), is involved in protein folding and degradation.","The Journal of biological chemistry","2012 May 25","Cali T, Fedrizzi L, Ottolini D, Gomez-Villafuertes R, Mellstrom B, Naranjo JR, Carafoli E, Brini M"
4822a5242
> "Q61411-1","30655611","WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.","Nature communications","2019 Jan 17","Jeong WJ, Park JC, Kim WS, Ro EJ, Jeon SH, Lee SK, Park YN, Min DS, Choi KY"
4824d5243
< "P27699-1","30228239","Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease.","mBio","2018 Sep 18","Wojcik GL, Marie C, Abhyankar MM, Yoshida N, Watanabe K, Mentzer AJ, Carstensen T, Mychaleckyj J, Kirkpatrick BD, Rich SS, Concannon P, Haque R, Tsokos GC, Petri WA Jr, Duggal P"
4826a5246,5247
> "P0C605-1","30327468","A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis.","Nature communications","2018 Oct 16","Wen L, Feil S, Wolters M, Thunemann M, Regler F, Schmidt K, Friebe A, Olbrich M, Langer H, Gawaz M, de Wit C, Feil R"
> "P0C605-1","30152261","Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion.","Molecular pain","2018 Jan-Dec","Uchida H, Matsumura S, Katano T, Watanabe M, Schlossmann J, Ito S"
4828,4829c5249
< "Q6NZN1-1","25994039","Resistance to high-fat diet-induced obesity in male heterozygous Pprc1 knockout mice.","Endocrine journal","2015","Zhai N, Sun C, Gu W, He X, Shan A, Sun H, Lu N, Cui B, Ning G"
< "Q6NZN1-1","22411706","Peri-implantation lethality in mice lacking the PGC-1-related coactivator protein.","Developmental dynamics : an official publication of the American Association of Anatomists","2012 May","He X, Sun C, Wang F, Shan A, Guo T, Gu W, Cui B, Ning G"
---
> "Q14BI1-1","18166528","SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.","The Journal of biological chemistry","2008 Feb 29","Ginger RS, Askew SE, Ogborne RM, Wilson S, Ferdinando D, Dadd T, Smith AM, Kazi S, Szerencsei RT, Winkfein RJ, Schnetkamp PP, Green MR"
4833a5254,5255
> "Q61730-1","25449578","The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice.","Brain, behavior, and immunity","2015 Jul","Davis CJ, Dunbrasky D, Oonk M, Taishi P, Opp MR, Krueger JM"
> "Q61730-1","25908590","Mechanisms of splicing-dependent trans-synaptic adhesion by PTPdelta-IL1RAPL1/IL-1RAcP for synaptic differentiation.","Nature communications","2015 Apr 24","Yamagata A, Yoshida T, Sato Y, Goto-Ito S, Uemura T, Maeda A, Shiroshima T, Iwasawa-Okamoto S, Mori H, Mishina M, Fukai S"
4836,4840d5257
< "Q4U4S6-1","25772365","XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia.","Cell reports","2015 Mar 24","Scheffer DI, Zhang DS, Shen J, Indzhykulian A, Karavitaki KD, Xu YJ, Wang Q, Lin JJ, Chen ZY, Corey DP"
< "Q4U4S6-1","25653358","A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Feb 4","Francis SP, Krey JF, Krystofiak ES, Cui R, Nanda S, Xu W, Kachar B, Barr-Gillespie PG, Shin JB"
< "Q4U4S6-1","23261932","The Xin repeat-containing protein, mXinbeta, initiates the maturation of the intercalated discs during postnatal heart development.","Developmental biology","2013 Feb 15","Wang Q, Lin JL, Chan SY, Lin JJ"
< "Q4U4S6-1","17046827","Myomaxin is a novel transcriptional target of MEF2A that encodes a Xin-related alpha-actinin-interacting protein.","The Journal of biological chemistry","2006 Dec 22","Huang HT, Brand OM, Mathew M, Ignatiou C, Ewen EP, McCalmon SA, Naya FJ"
< "Q4U4S6-1","16500513","A novel gene (Cmya3) induced in the heart by angiotensin II-dependent but not salt-dependent hypertension in mice.","American journal of hypertension","2006 Mar","Duka A, Schwartz F, Duka I, Johns C, Melista E, Gavras I, Gavras H"
4842c5259,5263
< "Q3TY86-1","19280713","Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria.","Free radical biology &amp; medicine","2009 Apr 1","Chinta SJ, Rane A, Yadava N, Andersen JK, Nicholls DG, Polster BM"
---
> "Q8R1R4-1","30573681","Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells.","The Journal of biological chemistry","2019 Feb 15","Ogawa S, Matsuoka Y, Takada M, Matsui K, Yamane F, Kubota E, Yasuhara S, Hieda K, Kanayama N, Hatano N, Tokumitsu H, Magari M"
> "Q8R1R4-1","27865758","Bone Morphogenetic Protein 2 and Transforming Growth Factor beta1 Inhibit the Expression of the Proinflammatory Cytokine IL-34 in Rheumatoid Arthritis Synovial Fibroblasts.","The American journal of pathology","2017 Jan","Chemel M, Brion R, Segaliny AI, Lamora A, Charrier C, Brulin B, Maugars Y, Le Goff B, Heymann D, Verrecchia F"
> "Q8R1R4-1","21494622","The critical role of IL-34 in osteoclastogenesis.","PloS one","2011 Apr 8","Chen Z, Buki K, Vaaraniemi J, Gu G, Vaananen HK"
> "Q8R1R4-1","20504948","Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.","Journal of leukocyte biology","2010 Sep","Wei S, Nandi S, Chitu V, Yeung YG, Yu W, Huang M, Williams LT, Lin H, Stanley ER"
> "Q91ZM9-1","24551065","The membrane-associated adaptor protein DOK5 is upregulated in systemic sclerosis and associated with IGFBP-5-induced fibrosis.","PloS one","2014","Yasuoka H, Yamaguchi Y, Feghali-Bostwick CA"
4855a5277
> "Q9DB07-1","17720815","Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish.","The Journal of biological chemistry","2007 Oct 19","Gouttenoire J, Valcourt U, Bougault C, Aubert-Foucher E, Arnaud E, Giraud L, Mallein-Gerin F"
4860a5283
> "Q8JZL7-1","20090772","Early endosome localization and activity of RasGEF1b, a toll-like receptor-inducible Ras guanine-nucleotide exchange factor.","Genes and immunity","2010 Sep","Andrade WA, Silva AM, Alves VS, Salgado AP, Melo MB, Andrade HM, Dall'Orto FV, Garcia SA, Silveira TN, Gazzinelli RT"
4867c5290,5291
< "Q6ZPQ6-1","26269578","RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells.","Molecular biology of the cell","2015 Oct 15","Walker MT, Rupp A, Elsaesser R, Guler AD, Sheng W, Weng S, Berson DM, Hattar S, Montell C"
---
> "Q7TQ62-1","15063725","Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family.","FEBS letters","2004 Apr 9","Shimizu-Hirota R, Sasamura H, Kuroda M, Kobayashi E, Saruta T"
> "Q91WK0-1","21220426","Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4)-mediated signaling.","The Journal of biological chemistry","2011 Apr 1","Gunawardena HP, Huang Y, Kenjale R, Wang H, Xie L, Chen X"
4874,4876c5298,5303
< "Q8CIV7-1","27310661","Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression.","PloS one","2016","Shen AL, Moran SA, Glover EA, Drinkwater NR, Swearingen RE, Teixeira LB, Bradfield CA"
< "Q8CIV7-1","26619963","OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.","Gastroenterology","2016 Mar","Ye GD, Sun GB, Jiao P, Chen C, Liu QF, Huang XL, Zhang R, Cai WY, Li SN, Wu JF, Liu YJ, Wu RS, Xie YY, Chan EC, Liou YC, Li BA"
< "Q8CIV7-1","12213202","Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice.","Genomics","2002 Sep","Li B, Dai Q, Li L, Nair M, Mackay DR, Dai X"
---
> "Q2EG98-1","21185261","The single pore residue Asp523 in PKD2L1 determines Ca2+ permeation of the PKD1L3/PKD2L1 complex.","Biochemical and biophysical research communications","2011 Jan 28","Fujimoto C, Ishimaru Y, Katano Y, Misaka T, Yamasoba T, Asakura T, Abe K"
> "Q2EG98-1","19464260","Acetic acid activates PKD1L3-PKD2L1 channel--a candidate sour taste receptor.","Biochemical and biophysical research communications","2009 Jul 31","Ishii S, Misaka T, Kishi M, Kaga T, Ishimaru Y, Abe K"
> "Q2EG98-1","18535624","Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1.","EMBO reports","2008 Jul","Inada H, Kawabata F, Ishimaru Y, Fushiki T, Matsunami H, Tominaga M"
> "Q2EG98-1","16891422","Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor.","Proceedings of the National Academy of Sciences of the United States of America","2006 Aug 15","Ishimaru Y, Inada H, Kubota M, Zhuang H, Tominaga M, Matsunami H"
> "Q2EG98-1","16805797","Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.","Journal of neurochemistry","2006 Jul","LopezJimenez ND, Cavenagh MM, Sainz E, Cruz-Ithier MA, Battey JF, Sullivan SL"
> "Q2EG98-1","12782129","Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes.","Genomics","2003 Jun","Li A, Tian X, Sung SW, Somlo S"
4883a5311,5317
> "Q9ET47-1","28516904","Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin.","Nature communications","2017 May 18","Lui NC, Tam WY, Gao C, Huang JD, Wang CC, Jiang L, Yung WH, Kwan KM"
> "Q6P2L6-1","28228401","Wolf-Hirschhorn syndrome candidate 1-like 1 epigenetically regulates nephrin gene expression.","American journal of physiology. Renal physiology","2017 Jun 1","Ito Y, Katayama K, Nishibori Y, Akimoto Y, Kudo A, Kurayama R, Hada I, Takahashi S, Kimura T, Fukutomi T, Katada T, Suehiro J, Beltcheva O, Tryggvason K, Yan K"
> "A2A432-1","30992047","Abnormal level of CUL4B-mediated histone H2A ubiquitination causes disruptive HOX gene expression.","Epigenetics &amp; chromatin","2019 Apr 16","Lin Y, Yu J, Wu J, Wang S, Zhang T"
> "A2A432-1","29106389","CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2.","Oncogene","2018 Feb 22","Qi M, Jiao M, Li X, Hu J, Wang L, Zou Y, Zhao M, Zhang R, Liu H, Mi J, Zhang L, Liu L, Gong Y, Han B"
> "A2A432-1","28604389","A cullin 4B-RING E3 ligase complex fine-tunes pancreatic delta cell paracrine interactions.","The Journal of clinical investigation","2017 Jun 30","Li Q, Cui M, Yang F, Li N, Jiang B, Yu Z, Zhang D, Wang Y, Zhu X, Hu H, Li PS, Ning SL, Wang S, Qi H, Song H, He D, Lin A, Zhang J, Liu F, Zhao J, Gao L, Yi F, Xue T, Sun JP, Gong Y, Yu X"
> "A2A432-1","17954973","Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin.","Journal of biosciences","2007 Sep","Tripathi R, Kota SK, Srinivas UK"
> "A2A432-1","16052071","Cloning and characterization of mouse cullin4B/E3 ubiquitin ligase.","Journal of biosciences","2005 Jun","Tripathi R, Sastry KS, Kota SK, Srinivas UK"
4898a5333,5335
> "A2APV2-1","28852060","FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42.","Scientific reports","2017 Aug 29","Kage F, Steffen A, Ellinger A, Ranftler C, Gehre C, Brakebusch C, Pavelka M, Stradal T, Rottner K"
> "A2APV2-1","28327544","FMNL formins boost lamellipodial force generation.","Nature communications","2017 Mar 22","Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, Bruhmann S, Kollasser J, Block J, Dimchev G, Geyer M, Schnittler HJ, Brakebusch C, Stradal TE, Carlier MF, Sixt M, Kas J, Faix J, Rottner K"
> "A2APV2-1","22608513","FMNL2 drives actin-based protrusion and migration downstream of Cdc42.","Current biology : CB","2012 Jun 5","Block J, Breitsprecher D, Kuhn S, Winterhoff M, Kage F, Geffers R, Duwe P, Rohn JL, Baum B, Brakebusch C, Geyer M, Stradal TE, Faix J, Rottner K"
4902c5339,5344
< "Q9D552-1","16395525","Expression and identification of a novel apoptosis gene Spata17 (MSRG-11) in mouse spermatogenic cells.","Acta biochimica et biophysica Sinica","2006 Jan","Deng Y, Hu LS, Lu GX"
---
> "Q8VBT9-1","25944897","Coordinated Regulation of Vasopressin Inactivation and Glucose Uptake by Action of TUG Protein in Muscle.","The Journal of biological chemistry","2015 Jun 5","Habtemichael EN, Alcazar-Roman A, Rubin BR, Grossi LR, Belman JP, Julca O, Loffler MG, Li H, Chi NW, Samuel VT, Bogan JS"
> "Q8VBT9-1","25453902","Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment.","Cancer cell","2014 Dec 8","Goodwin ML, Jin H, Straessler K, Smith-Fry K, Zhu JF, Monument MJ, Grossmann A, Randall RL, Capecchi MR, Jones KB"
> "Q8VBT9-1","23744065","Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle.","The Journal of biological chemistry","2013 Jul 12","Loffler MG, Birkenfeld AL, Philbrick KM, Belman JP, Habtemichael EN, Booth CJ, Castorena CM, Choi CS, Jornayvaz FR, Gassaway BM, Lee HY, Cartee GD, Philbrick W, Shulman GI, Samuel VT, Bogan JS"
> "Q8VBT9-1","22610098","Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocation.","The Journal of biological chemistry","2012 Jul 6","Bogan JS, Rubin BR, Yu C, Loffler MG, Orme CM, Belman JP, McNally LJ, Hao M, Cresswell JA"
> "Q8VBT9-1","17202135","The glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytes.","The Journal of biological chemistry","2007 Mar 9","Yu C, Cresswell J, Loffler MG, Bogan JS"
> "Q8VBT9-1","14562105","Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking.","Nature","2003 Oct 16","Bogan JS, Hendon N, McKee AE, Tsao TS, Lodish HF"
4905a5348
> "Q6A078-1","30446612","Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model.","Proceedings of the National Academy of Sciences of the United States of America","2018 Dec 4","Ramsbottom SA, Molinari E, Srivastava S, Silberman F, Henry C, Alkanderi S, Devlin LA, White K, Steel DH, Saunier S, Miles CG, Sayer JA"
4906a5350,5351
> "Q8BGQ7-1","29769718","ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase.","Nature","2018 May","Vo MN, Terrey M, Lee JW, Roy B, Moresco JJ, Sun L, Fu H, Liu Q, Weber TG, Yates JR 3rd, Fredrick K, Schimmel P, Ackerman SL"
> "Q8BGQ7-1","16906134","Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.","Nature","2006 Sep 7","Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Sundberg JP, Schimmel P, Ackerman SL"
4913,4915d5357
< "Q9ESZ8-1","31011227","Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug.","Nature neuroscience","2019 May","Barak B, Zhang Z, Liu Y, Nir A, Trangle SS, Ennis M, Levandowski KM, Wang D, Quast K, Boulting GL, Li Y, Bayarsaihan D, He Z, Feng G"
< "Q9ESZ8-1","29568691","Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams-Beuren syndrome and autism spectrum disorder.","Brain and behavior","2018 Jan","Martin LA, Iceberg E, Allaf G"
< "Q9ESZ8-1","27194223","Generation of a mouse model for a conditional inactivation of Gtf2i allele.","Genesis (New York, N.Y. : 2000)","2016 Jul","Enkhmandakh B, Stoddard C, Mack K, He W, Kaback D, Yee SP, Bayarsaihan D"
4918d5359
< "Q8CG46-1","28302748","SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.","Development (Cambridge, England)","2017 May 1","Hwang G, Sun F, O'Brien M, Eppig JJ, Handel MA, Jordan PW"
4920a5362
> "Q9WTX6-1","27063938","Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.","eLife","2016 Apr 11","Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, Gu Y, Su X, Xia M, Li W, Zhang X, Wang Q, Cao X, Wang J"
4922a5365
> "Q3UZ01-1","30254136","Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective Rnpc3-deficient mice.","RNA (New York, N.Y.)","2018 Dec","Doggett K, Williams BB, Markmiller S, Geng FS, Coates J, Mieruszynski S, Ernst M, Thomas T, Heath JK"
4929a5373,5375
> "Q3UPW2-1","27222093","E74-like factor 3 and nuclear factor-kappaB regulate lipocalin-2 expression in chondrocytes.","The Journal of physiology","2016 Nov 1","Conde J, Otero M, Scotece M, Abella V, Lopez V, Pino J, Gomez R, Lago F, Goldring MB, Gualillo O"
> "Q3UPW2-1","11893733","Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1.","The Journal of biological chemistry","2002 May 17","Kim JH, Wilder PJ, Hou J, Nowling T, Rizzino A"
> "D3YVL2-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
4934a5381,5387
> "Q8R0I0-1","29679094","Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.","Cellular and molecular life sciences : CMLS","2018 Oct","Klempin F, Mosienko V, Matthes S, Villela DC, Todiras M, Penninger JM, Bader M, Santos RAS, Alenina N"
> "Q8R0I0-1","29990483","Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.","Life sciences","2018 Sep 1","Liu J, Chen Q, Liu S, Yang X, Zhang Y, Huang F"
> "Q8R0I0-1","29884907","Sex dimorphism in ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy.","Laboratory investigation; a journal of technical methods and pathology","2018 Sep","Clotet-Freixas S, Soler MJ, Palau V, Anguiano L, Gimeno J, Konvalinka A, Pascual J, Riera M"
> "Q8R0I0-1","15452268","Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.","Journal of virology","2004 Oct","Li W, Greenough TC, Moore MJ, Vasilieva N, Somasundaran M, Sullivan JL, Farzan M, Choe H"
> "Q8R0I0-1","12487024","Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2).","DNA sequence : the journal of DNA sequencing and mapping","2002 Aug","Komatsu T, Suzuki Y, Imai J, Sugano S, Hida M, Tanigami A, Muroi S, Yamada Y, Hanaoka K"
> "Q8R0I0-1","12075344","Angiotensin-converting enzyme 2 is an essential regulator of heart function.","Nature","2002 Jun 20","Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM"
> "O54918-1","30590105","c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson's Disease.","Neuroscience","2019 Feb 10","Hu K, Huang Q, Liu C, Li Y, Liu Y, Wang H, Li M, Ma S"
4935a5389
> "Q6NSU3-1","29483533","Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes.","Nature communications","2018 Feb 26","Yang CP, Li X, Wu Y, Shen Q, Zeng Y, Xiong Q, Wei M, Chen C, Liu J, Huo Y, Li K, Xue G, Yao YG, Zhang C, Li M, Chen Y, Luo XJ"
4936a5391,5396
> "Q60668-1","30418981","Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each.","PloS one","2018","Dogar AM, Pauchard-Batschulat R, Grisoni-Neupert B, Richman L, Paillusson A, Pradervand S, Hagenbuchle O, Ambrosini G, Schmid CD, Bucher P, Kuhn LC"
> "Q60668-1","27784781","Autotaxin Expression Is Regulated at the Post-transcriptional Level by the RNA-binding Proteins HuR and AUF1.","The Journal of biological chemistry","2016 Dec 9","Sun S, Zhang X, Lyu L, Li X, Yao S, Zhang J"
> "Q60668-1","27452471","Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity.","Cell reports","2016 Aug 2","Chenette DM, Cadwallader AB, Antwine TL, Larkin LC, Wang J, Olwin BB, Schneider RJ"
> "Q60668-1","24891619","RNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels.","Molecular and cellular biology","2014 Aug","Panda AC, Abdelmohsen K, Yoon JH, Martindale JL, Yang X, Curtis J, Mercken EM, Chenette DM, Zhang Y, Schneider RJ, Becker KG, de Cabo R, Gorospe M"
> "Q60668-1","14715706","Interaction between 3' untranslated region of calcitonin receptor messenger ribonucleic acid (RNA) and adenylate/uridylate (AU)-rich element binding proteins (AU-rich RNA-binding factor 1 and Hu antigen R).","Endocrinology","2004 Apr","Yasuda S, Wada S, Arao Y, Kogawa M, Kayama F, Katayama S"
> "Q60668-1","12107167","Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1.","The Journal of biological chemistry","2002 Sep 20","Pioli PA, Hamilton BJ, Connolly JE, Brewer G, Rigby WF"
4942a5403
> "Q8C7H1-1","23022071","The methylmalonic aciduria related genes, Mmaa, Mmab, and Mut, are broadly expressed in placental and embryonic tissues during mouse organogenesis.","Molecular genetics and metabolism","2012 Nov","Moreno-Garcia MA, Rosenblatt DS, Jerome-Majewska LA"
4944a5406,5408
> "Q8BK03-1","28938432","Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.","Endocrinology","2017 Nov 1","Liu XM, Zhang YL, Ji SY, Zhao LW, Shang WN, Li D, Chen Z, Tong C, Fan HY"
> "Q8BK03-1","26716412","Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions.","Oncotarget","2016 Jan 12","Liu XM, Zhang YP, Ji SY, Li BT, Tian X, Li D, Tong C, Fan HY"
> "Q8BK03-1","26711011","Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.","Molecular cell","2016 Jan 7","Zhang Y, Liu X, Bai J, Tian X, Zhao X, Liu W, Duan X, Shang W, Fan HY, Tong C"
4949a5414,5415
> "Q8R3V5-4","28455444","Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection.","The Journal of biological chemistry","2017 Jun 16","Serfass JM, Takahashi Y, Zhou Z, Kawasawa YI, Liu Y, Tsotakos N, Young MM, Tang Z, Yang L, Atkinson JM, Chroneos ZC, Wang HG"
> "Q8R3V5-4","18303116","SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade.","Proceedings of the National Academy of Sciences of the United States of America","2008 Mar 4","Fasso M, Waitz R, Hou Y, Rim T, Greenberg NM, Shastri N, Fong L, Allison JP"
4958,4960c5424,5425
< "Q8BG60-1","30138646","Increased thioredoxin-interacting protein in brain of mice exposed to chronic stress.","Progress in neuro-psychopharmacology &amp; biological psychiatry","2019 Jan 10","Zhou H, Tan H, Letourneau L, Wang JF"
< "Q8BG60-1","30142540","TXNIP mediated the oxidative stress response in glomerular mesangial cells partially through AMPK pathway.","Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie","2018 Nov","Xu W, Wang L, Li J, Cai Y, Xue Y"
< "Q8BG60-1","29884908","Thioredoxin-interacting protein deficiency ameliorates kidney inflammation and fibrosis in mice with unilateral ureteral obstruction.","Laboratory investigation; a journal of technical methods and pathology","2018 Sep","Wu M, Li R, Hou Y, Song S, Han W, Chen N, Du Y, Ren Y, Shi Y"
---
> "Q3UFK8-1","29897336","FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.","eLife","2018 Jun 13","Kunzel U, Grieve AG, Meng Y, Sieber B, Cowley SA, Freeman M"
> "Q3UFK8-1","29897333","iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.","eLife","2018 Jun 13","Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, Clancy D, Brezinova J, Hu T, Bileck A, Gerner C, Bolado A, von Kriegsheim A, Martin SJ, Steinberg F, Strisovsky K, Adrain C"
4969a5435
> "Q99LI8-1","25296754","ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.","The Journal of biological chemistry","2014 Nov 28","Kojima K, Amano Y, Yoshino K, Tanaka N, Sugamura K, Takeshita T"
4973a5440,5444
> "Q8CGN5-1","30042231","Perilipin 1 (Plin1) deficiency promotes inflammatory responses in lean adipose tissue through lipid dysregulation.","The Journal of biological chemistry","2018 Sep 7","Sohn JH, Lee YK, Han JS, Jeon YG, Kim JI, Choe SS, Kim SJ, Yoo HJ, Kim JB"
> "Q8CGN5-1","29407594","Overexpression of perilipin1 protects against atheroma progression in apolipoprotein E knockout mice.","Atherosclerosis","2018 Feb","Yamamoto K, Miyoshi H, Cho KY, Nakamura A, Greenberg AS, Atsumi T"
> "Q8CGN5-1","29191637","Spontaneous development of hepatosteatosis in perilipin-1 null mice with adipose tissue dysfunction.","Biochimica et biophysica acta. Molecular and cell biology of lipids","2018 Feb","Wei S, Liu S, Su X, Wang W, Li F, Deng J, Lyu Y, Geng B, Xu G"
> "Q8CGN5-1","12407111","The central domain is required to target and anchor perilipin A to lipid droplets.","The Journal of biological chemistry","2003 Jan 3","Garcia A, Sekowski A, Subramanian V, Brasaemle DL"
> "Q8CGN5-1","11751901","Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system.","The Journal of biological chemistry","2002 Mar 8","Souza SC, Muliro KV, Liscum L, Lien P, Yamamoto MT, Schaffer JE, Dallal GE, Wang X, Kraemer FB, Obin M, Greenberg AS"
4990a5462,5464
> "Q8K2C7-1","26721884","OS9 Protein Interacts with Na-K-2Cl Co-transporter (NKCC2) and Targets Its Immature Form for the Endoplasmic Reticulum-associated Degradation Pathway.","The Journal of biological chemistry","2016 Feb 26","Seaayfan E, Defontaine N, Demaretz S, Zaarour N, Laghmani K"
> "Q8K2C7-1","21523322","Osteosarcoma amplified 9 is highly expressed in mouse adipocytes and controls lipid storage.","Molecular medicine reports","2011 Jul-Aug","Yu L, Nian Z, Sang J"
> "Q8K2C7-1","17932042","OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.","The Journal of biological chemistry","2007 Dec 14","Wang Y, Fu X, Gaiser S, Kottgen M, Kramer-Zucker A, Walz G, Wegierski T"
5000a5475
> "Q8K2H6-1","22190705","Experimental validation of Ankrd17 and Anapc10, two novel meiotic genes predicted by computational models in mice.","Biology of reproduction","2012 Apr","Ray D, Hogarth CA, Evans EB, An W, Griswold MD, Ye P"
5003a5479,5480
> "Q04863-1","30037996","Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation.","Proceedings of the National Academy of Sciences of the United States of America","2018 Aug 7","Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D"
> "Q3TRM4-1","17015841","Neuropathy target esterase catalyzes osmoprotective renal synthesis of glycerophosphocholine in response to high NaCl.","Proceedings of the National Academy of Sciences of the United States of America","2006 Oct 10","Gallazzini M, Ferraris JD, Kunin M, Morris RG, Burg MB"
5011,5012d5487
< "O08795-1","22337885","TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis.","The Journal of biological chemistry","2012 Apr 6","Yaguchi H, Okumura F, Takahashi H, Kano T, Kameda H, Uchigashima M, Tanaka S, Watanabe M, Sasaki H, Hatakeyama S"
< "O08795-1","21995826","A cis-acting region in the N-methyl-d-aspartate R1 3'-untranslated region interacts with the novel RNA-binding proteins beta subunit of alpha glucosidase II and annexin A2--effect of chronic ethanol exposure in vivo.","The European journal of neuroscience","2011 Oct","Anji A, Kumari M"
5016a5492,5497
> "Q7TNT2-1","30372477","Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia.","PloS one","2018","Sundberg JP, Shen T, Fiehn O, Rice RH, Silva KA, Kennedy VE, Gott NE, Dionne LA, Bechtold LS, Murray SA, Kuiper R, Pratt CH"
> "Q7TNT2-1","24009241","Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene.","Journal of the American Society of Nephrology : JASN","2013 Dec","Noordmans GA, Caputo CR, Huang Y, Sheehan SM, Bulthuis M, Heeringa P, Hillebrands JL, van Goor H, Korstanje R"
> "Q7TNT2-1","15220349","Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.","The Journal of biological chemistry","2004 Sep 3","Cheng JB, Russell DW"
> "Q7TNT2-1","15220348","Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.","The Journal of biological chemistry","2004 Sep 3","Cheng JB, Russell DW"
> "Q91WA4-1","26462610","CXXC5 plays a role as a transcription activator for myelin genes on oligodendrocyte differentiation.","Glia","2016 Mar","Kim MY, Kim HY, Hong J, Kim D, Lee H, Cheong E, Lee Y, Roth J, Kim DG, Min do S, Choi KY"
> "Q91WA4-1","26056233","The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing.","The Journal of experimental medicine","2015 Jun 29","Lee SH, Kim MY, Kim HY, Lee YM, Kim H, Nam KA, Roh MR, Min do S, Chung KY, Choi KY"
5018a5500,5502
> "E9Q238-1","29158259","Structural analyses of key features in the KANK1.KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex.","The Journal of biological chemistry","2018 Jan 5","Weng Z, Shang Y, Yao D, Zhu J, Zhang R"
> "Q3UHD6-1","27974614","SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2016 Dec 14","Wang X, Zhou Y, Wang J, Tseng IC, Huang T, Zhao Y, Zheng Q, Gao Y, Luo H, Zhang X, Bu G, Hong W, Xu H"
> "Q3UHD6-1","15466885","New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.","Journal of cell science","2004 Oct 15","Joubert L, Hanson B, Barthet G, Sebben M, Claeysen S, Hong W, Marin P, Dumuis A, Bockaert J"
5022,5026d5505
< "Q8BPM6-1","27129882","RIC-3 expression and splicing regulate nAChR functional expression.","Molecular brain","2016 Apr 29","Ben-David Y, Mizrachi T, Kagan S, Krisher T, Cohen E, Brenner T, Treinin M"
< "Q8BPM6-1","20668195","Ric-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2010 Jul 28","Alexander JK, Sagher D, Krivoshein AV, Criado M, Jefford G, Green WN"
< "Q8CHD8-1","24576489","Endosomal localization of FIP3/Arfophilin-1 and its involvement in dendritic formation of mouse hippocampal neurons.","Brain research","2014 Apr 4","Yazaki Y, Hara Y, Tamaki H, Fukaya M, Sakagami H"
< "Q8CHD8-1","20736163","A novel cytoplasmic adaptor for retinoic acid receptor (RAR) and thyroid receptor functions as a Derepressor of RAR in the absence of retinoic acid.","The Journal of biological chemistry","2010 Oct 29","Park UH, Kim EJ, Um SJ"
< "Q8CHD8-1","15601896","The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.","Molecular biology of the cell","2005 Feb","Wilson GM, Fielding AB, Simon GC, Yu X, Andrews PD, Hames RS, Frey AM, Peden AA, Gould GW, Prekeris R"
5027a5507
> "Q9DD06-1","30576947","Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and beta-arrestin 2 in inflammatory macrophages.","Molecular immunology","2019 Feb","Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ"
5034,5035c5514,5516
< "P70170-1","28121062","Exposure to 15% oxygen in vivo up-regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK.","Journal of cellular and molecular medicine","2017 Jul","Mohammed Abdul KS, Jovanovic S, Jovanovic A"
< "P70170-1","27086859","Regulation of myometrial contraction by ATP-sensitive potassium (KATP) channel via activation of SUR2B and Kir 6.2 in mouse.","The Journal of veterinary medical science","2016 Aug 1","Hong SH, Kyeong KS, Kim CH, Kim YC, Choi W, Yoo RY, Kim HS, Park YJ, Ji IW, Jeong EH, Kim HS, Xu WX, Lee SJ"
---
> "O88839-1","25650586","A disintegrin and metallproteinase 15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.","Molecular medicine reports","2015 Jun","Gao J, Zheng W, Wang L, Song B"
> "O88839-1","25249606","Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.","Investigative ophthalmology &amp; visual science","2014 Sep 23","Maretzky T, Blobel CP, Guaiquil V"
> "O88839-1","23161886","ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.","American journal of physiology. Lung cellular and molecular physiology","2013 Feb 1","Sun C, Beard RS Jr, McLean DL, Rigor RR, Konia T, Wu MH, Yuan SY"
5037a5519
> "Q91X78-1","30135210","The erlin2 T65I mutation inhibits erlin1/2 complex-mediated inositol 1,4,5-trisphosphate receptor ubiquitination and phosphatidylinositol 3-phosphate binding.","The Journal of biological chemistry","2018 Oct 5","Wright FA, Bonzerato CG, Sliter DA, Wojcikiewicz RJH"
5041,5048d5522
< "Q810L3-1","26566864","CHFR is important for the survival of male premeiotic germ cells.","Cell cycle (Georgetown, Tex.)","2015","Lu LY, Yu X"
< "Q810L3-1","22337872","CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.","The Journal of biological chemistry","2012 Apr 13","Kashima L, Idogawa M, Mita H, Shitashige M, Yamada T, Ogi K, Suzuki H, Toyota M, Ariga H, Sasaki Y, Tokino T"
< "Q810L3-1","22285184","SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components.","Biochemical and biophysical research communications","2012 Feb 17","Jung I, Sohn DH, Choi J, Kim JM, Jeon S, Seol JH, Seong RH"
< "Q810L3-1","21706008","Chfr and RNF8 synergistically regulate ATM activation.","Nature structural &amp; molecular biology","2011 Jun 26","Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X"
< "Q810L3-1","21245198","The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr.","Journal of cell science","2011 Feb 15","Castiel A, Danieli MM, David A, Moshkovitz S, Aplan PD, Kirsch IR, Brandeis M, Kramer A, Izraeli S"
< "Q810L3-1","19690386","Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.","The Journal of clinical investigation","2009 Sep","Fu Z, Regan K, Zhang L, Muders MH, Thibodeau SN, French A, Wu Y, Kaufmann SH, Lingle WL, Chen J, Tindall DJ"
< "Q810L3-1","15793587","Chfr is required for tumor suppression and Aurora A regulation.","Nature genetics","2005 Apr","Yu X, Minter-Dykhouse K, Malureanu L, Zhao WM, Zhang D, Merkle CJ, Ward IM, Saya H, Fang G, van Deursen J, Chen J"
< "Q810L3-1","15467728","PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.","Nature structural &amp; molecular biology","2004 Nov","Daniels MJ, Marson A, Venkitaraman AR"
5056c5530,5531
< "Q8R2U0-1","20824097","Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.","PLoS pathogens","2010 Sep 2","Ahn SH, Deshmukh H, Johnson N, Cowell LG, Rude TH, Scott WK, Nelson CL, Zaas AK, Marchuk DA, Keum S, Lamlertthon S, Sharma-Kuinkel BK, Sempowski GD, Fowler VG Jr"
---
> "Q9Z0P7-1","29515120","Itch/beta-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.","Nature communications","2018 Mar 7","Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazza D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L"
> "Q3UA16-1","21084868","Perturbation of Spc25 expression affects meiotic spindle organization, chromosome alignment and spindle assembly checkpoint in mouse oocytes.","Cell cycle (Georgetown, Tex.)","2010 Nov 15","Sun SC, Lee SE, Xu YN, Kim NH"
5060a5536,5538
> "Q9ES63-1","29734399","Allele and dosage specificity of the Peg3 imprinted domain.","PloS one","2018","Bretz CL, Frey WD, Teruyama R, Kim J"
> "Q8K202-1","28042089","PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression.","Gene","2017 May 15","Rothblum LI, Rothblum K, Chang E"
> "Q8K202-1","22849406","Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49.","Biochemistry","2012 Aug 21","Penrod Y, Rothblum K, Rothblum LI"
5061a5540
> "Q9JIW9-1","27269287","Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.","Cellular signalling","2016 Sep","Pawar A, Meier JA, Dasgupta A, Diwanji N, Deshpande N, Saxena K, Buwa N, Inchanalkar S, Schwartz MA, Balasubramanian N"
5064a5544,5550
> "Q80TJ7-1","29317619","Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway.","Nature communications","2018 Jan 9","Chen X, Wang S, Zhou Y, Han Y, Li S, Xu Q, Xu L, Zhu Z, Deng Y, Yu L, Song L, Chen AP, Song J, Takahashi E, He G, He L, Li W, Chen CD"
> "Q80TJ7-1","28485378","Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.","Nature communications","2017 May 9","Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K"
> "Q80TJ7-1","26866517","Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1.","Stem cells (Dayton, Ohio)","2016 Jun","Tang Y, Hong YZ, Bai HJ, Wu Q, Chen CD, Lang JY, Boheler KR, Yang HT"
> "Q80TJ7-1","25921086","The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload.","Experimental cell research","2015 Jul 1","Liu X, Wang X, Bi Y, Bu P, Zhang M"
> "Q80TJ7-1","16199551","Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate.","Journal of medical genetics","2005 Oct","Laumonnier F, Holbert S, Ronce N, Faravelli F, Lenzner S, Schwartz CE, Lespinasse J, Van Esch H, Lacombe D, Goizet C, Phan-Dinh Tuy F, van Bokhoven H, Fryns JP, Chelly J, Ropers HH, Moraine C, Hamel BC, Briault S"
> "Q9ESD7-1","29771357","A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.","Human molecular genetics","2018 Aug 15","Barzilai-Tutsch H, Dewulf M, Lamaze C, Butler Browne G, Pines M, Halevy O"
> "Q9ESD7-1","11959863","Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.","The Journal of biological chemistry","2002 Jun 21","Davis DB, Doherty KR, Delmonte AJ, McNally EM"
5075a5562,5569
> "Q8VBT3-1","23817038","Monocytic expression of osteoclast-associated receptor (OSCAR) is induced in atherosclerotic mice and regulated by oxidized low-density lipoprotein in vitro.","Biochemical and biophysical research communications","2013 Jul 26","Sinningen K, Rauner M, Goettsch C, Al-Fakhri N, Schoppet M, Hofbauer LC"
> "Q8VBT3-1","21841309","OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice.","The Journal of clinical investigation","2011 Sep","Barrow AD, Raynal N, Andersen TL, Slatter DA, Bihan D, Pugh N, Cella M, Kim T, Rho J, Negishi-Koga T, Delaisse JM, Takayanagi H, Lorenzo J, Colonna M, Farndale RW, Choi Y, Trowsdale J"
> "Q8VBT3-1","18762192","Upstream stimulatory factors regulate OSCAR gene expression in RANKL-mediated osteoclast differentiation.","Journal of molecular biology","2008 Nov 14","Kim JH, Kim K, Jin HM, Youn BU, Song I, Choi HS, Kim N"
> "Q8VBT3-1","17442941","Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor.","Journal of immunology (Baltimore, Md. : 1950)","2007 May 1","Kim K, Lee J, Kim JH, Jin HM, Zhou B, Lee SY, Kim N"
> "Q8VBT3-1","16109714","Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis.","The Journal of biological chemistry","2005 Oct 21","Kim K, Kim JH, Lee J, Jin HM, Lee SH, Fisher DE, Kook H, Kim KK, Choi Y, Kim N"
> "Q8VBT3-1","16046394","Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis.","The Journal of biological chemistry","2005 Sep 23","Kim Y, Sato K, Asagiri M, Morita I, Soma K, Takayanagi H"
> "Q8VBT3-1","15184345","Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR).","International immunology","2004 Jul","Ishikawa S, Arase N, Suenaga T, Saita Y, Noda M, Kuriyama T, Arase H, Saito T"
> "Q8VBT3-1","12695521","Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.","The Journal of biological chemistry","2003 Jun 27","So H, Rho J, Jeong D, Park R, Fisher DE, Ostrowski MC, Choi Y, Kim N"
5081a5576,5579
> "O70458-1","30134804","OSMR gene effect on the pathogenesis of chronic autoimmune Urticaria via the JAK/STAT3 pathway.","Molecular medicine (Cambridge, Mass.)","2018 Jun 5","Luo XY, Liu Q, Yang H, Tan Q, Gan LQ, Ren FL, Wang H"
> "Q9D2F5-1","23028632","The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O(6)-methylguanine.","PloS one","2012","Fujikane R, Sanada M, Sekiguchi M, Hidaka M"
> "Q3UPF5-1","23776219","Prenylome profiling reveals S-farnesylation is crucial for membrane targeting and antiviral activity of ZAP long-isoform.","Proceedings of the National Academy of Sciences of the United States of America","2013 Jul 2","Charron G, Li MM, MacDonald MR, Hang HC"
> "Q3UPF5-1","22951821","Zinc finger antiviral protein inhibits murine gammaherpesvirus 68 M2 expression and regulates viral latency in cultured cells.","Journal of virology","2012 Nov","Xuan Y, Liu L, Shen S, Deng H, Gao G"
5096a5595,5597
> "Q5DTL9-1","24905082","Neuron type- and input pathway-dependent expression of Slc4a10 in adult mouse brains.","The European journal of neuroscience","2014 Sep","Song X, Yamasaki M, Miyazaki T, Konno K, Uchigashima M, Watanabe M"
> "Q5DTL9-1","15567717","Expression of the sodium-driven chloride bicarbonate exchanger NCBE during prenatal mouse development.","Gene expression patterns : GEP","2004 Dec","Hubner CA, Hentschke M, Jacobs S, Hermans-Borgmeyer I"
> "Q5DTL9-1","14592810","A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.","American journal of physiology. Cell physiology","2004 Mar","Praetorius J, Nejsum LN, Nielsen S"
5097a5599,5600
> "Q8R4T9-1","27914708","Generation and phenotypic analysis of mice lacking all urea transporters.","Kidney international","2017 Feb","Jiang T, Li Y, Layton AT, Wang W, Sun Y, Li M, Zhou H, Yang B"
> "Q8R4T9-1","12952854","Expression of urea transporters in potassium-depleted mouse kidney.","American journal of physiology. Renal physiology","2003 Dec","Jung JY, Madsen KM, Han KH, Yang CW, Knepper MA, Sands JM, Kim J"
5102,5104c5605,5606
< "Q60929-1","29054930","The transcription factor MEF2A fine-tunes gene expression in the atrial and ventricular chambers of the adult heart.","The Journal of biological chemistry","2017 Dec 22","Medrano JL, Naya FJ"
< "Q60929-1","28965945","AKT2 deficiency induces retardation of myocyte development through EndoG-MEF2A signaling in mouse heart.","Biochemical and biophysical research communications","2017 Dec 2","Chen D, Chen F, Xu Y, Zhang Y, Li Z, Zhang H, Pan T, Su Y, Wan M, Wang X, Ye J"
< "Q60929-1","28901289","Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D.","eLife","2017 Sep 13","Chang CW, Wilkerson JR, Hale CF, Gibson JR, Huber KM"
---
> "A4QPC6-1","26809444","Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.","The Journal of experimental medicine","2016 Feb 8","Sarter K, Leimgruber E, Gobet F, Agrawal V, Dunand-Sauthier I, Barras E, Mastelic-Gavillet B, Kamath A, Fontannaz P, Guery L, Duraes Fdo V, Lippens C, Ravn U, Santiago-Raber ML, Magistrelli G, Fischer N, Siegrist CA, Hugues S, Reith W"
> "A4QPC6-1","20208008","BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.","Journal of immunology (Baltimore, Md. : 1950)","2010 Apr 1","Smith IA, Knezevic BR, Ammann JU, Rhodes DA, Aw D, Palmer DB, Mather IH, Trowsdale J"
5105a5608
> "Q99NF1-1","21106934","A mitochondrial enzyme degrades carotenoids and protects against oxidative stress.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2011 Mar","Amengual J, Lobo GP, Golczak M, Li HN, Klimova T, Hoppel CL, Wyss A, Palczewski K, von Lintig J"
5112c5615,5620
< "Q91YM4-1","18255060","Epigenetic modifications and chromatin loop organization explain the different expression profiles of the Tbrg4, WAP and Ramp3 genes.","Experimental cell research","2008 Mar 10","Montazer-Torbati MB, Hue-Beauvais C, Droineau S, Ballester M, Coant N, Aujean E, Petitbarat M, Rijnkels M, Devinoy E"
---
> "P23708-1","29530977","Regulation of hepatic gluconeogenesis by nuclear factor Y transcription factor in mice.","The Journal of biological chemistry","2018 May 18","Zhang Y, Guan Q, Liu Y, Zhang Y, Chen Y, Chen J, Liu Y, Su Z"
> "P23708-1","28281280","A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.","FEBS letters","2017 Apr","Nishi-Tatsumi M, Yahagi N, Takeuchi Y, Toya N, Takarada A, Murayama Y, Aita Y, Sawada Y, Piao X, Oya Y, Shikama A, Masuda Y, Kubota M, Izumida Y, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Kawakami Y, Kadowaki T, Yamada N, Shimano H"
> "P23708-1","27837431","Obesity-induced endoplasmic reticulum stress suppresses nuclear factor-Y expression.","Molecular and cellular biochemistry","2017 Feb","Liu Y, Zhang Y, Zhang Y, Zhang J, Liu Y, Feng P, Su Z"
> "O55222-1","29787808","Lipoxin A4 and its analog suppress hepatocarcinoma cell epithelial-mesenchymal transition, migration and metastasis via regulating integrin-linked kinase axis.","Prostaglandins &amp; other lipid mediators","2018 Jul","Xu F, Zhou X, Hao J, Dai H, Zhang J, He Y, Hao H"
> "Q61036-1","29860311","PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.","Human molecular genetics","2018 Aug 15","Bondar VV, Adamski CJ, Onur TS, Tan Q, Wang L, Diaz-Garcia J, Park J, Orr HT, Botas J, Zoghbi HY"
> "Q61036-1","27940202","The intellectual disability protein PAK3 regulates oligodendrocyte precursor cell differentiation.","Neurobiology of disease","2017 Feb","Maglorius Renkilaraj MRL, Baudouin L, Wells CM, Doulazmi M, Wehrle R, Cannaya V, Bachelin C, Barnier JV, Jia Z, Nait Oumesmar B, Dusart I, Bouslama-Oueghlani L"
5114a5623
> "Q91ZV3-1","24177422","Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis.","The Journal of clinical investigation","2013 Dec","Nie L, Guo X, Esmailzadeh L, Zhang J, Asadi A, Collinge M, Li X, Kim JD, Woolls M, Jin SW, Dubrac A, Eichmann A, Simons M, Bender JR, Sadeghi MM"
5116,5117d5624
< "Q9R0Y5-1","24740601","Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm.","Biology of reproduction","2014 Jun","Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL"
< "Q9R0Y5-1","23447692","CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation.","Journal of immunology (Baltimore, Md. : 1950)","2013 Apr 1","Guo L, Stripay JL, Zhang X, Collage RD, Hulver M, Carchman EH, Howell GM, Zuckerbraun BS, Lee JS, Rosengart MR"
5121a5629
> "Q9D3X8-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
5122a5631
> "O88286-1","16702210","Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP.","The Journal of biological chemistry","2006 Jul 21","Ueda J, Tachibana M, Ikura T, Shinkai Y"
5138,5140c5647,5650
< "Q8K2C7-1","26721884","OS9 Protein Interacts with Na-K-2Cl Co-transporter (NKCC2) and Targets Its Immature Form for the Endoplasmic Reticulum-associated Degradation Pathway.","The Journal of biological chemistry","2016 Feb 26","Seaayfan E, Defontaine N, Demaretz S, Zaarour N, Laghmani K"
< "Q8K2C7-1","21523322","Osteosarcoma amplified 9 is highly expressed in mouse adipocytes and controls lipid storage.","Molecular medicine reports","2011 Jul-Aug","Yu L, Nian Z, Sang J"
< "Q8K2C7-1","17932042","OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.","The Journal of biological chemistry","2007 Dec 14","Wang Y, Fu X, Gaiser S, Kottgen M, Kramer-Zucker A, Walz G, Wegierski T"
---
> "Q99LG0-1","27586445","An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome.","Scientific reports","2016 Sep 2","Guedj F, Pennings JL, Massingham LJ, Wick HC, Siegel AE, Tantravahi U, Bianchi DW"
> "Q99LG0-1","24025767","Usp16 contributes to somatic stem-cell defects in Down's syndrome.","Nature","2013 Sep 19","Adorno M, Sikandar S, Mitra SS, Kuo A, Nicolis Di Robilant B, Haro-Acosta V, Ouadah Y, Quarta M, Rodriguez J, Qian D, Reddy VM, Cheshier S, Garner CC, Clarke MF"
> "Q6P9K9-1","9856994","Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.","The Journal of biological chemistry","1998 Dec 25","Missler M, Hammer RE, Sudhof TC"
> "Q6P9K9-1","8163501","Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.","The Journal of biological chemistry","1994 Apr 22","Ushkaryov YA, Hata Y, Ichtchenko K, Moomaw C, Afendis S, Slaughter CA, Sudhof TC"
5141a5652,5656
> "Q3UK78-1","29054931","Polycomb group RING finger proteins 3/5 activate transcription via an interaction with the pluripotency factor Tex10 in embryonic stem cells.","The Journal of biological chemistry","2017 Dec 29","Zhao W, Huang Y, Zhang J, Liu M, Ji H, Wang C, Cao N, Li C, Xia Y, Jiang Q, Qin J"
> "Q3UK78-1","29220657","hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing.","Molecular cell","2017 Dec 7","Pintacuda G, Wei G, Roustan C, Kirmizitas BA, Solcan N, Cerase A, Castello A, Mohammed S, Moindrot B, Nesterova TB, Brockdorff N"
> "Q3UK78-1","28596365","PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.","Science (New York, N.Y.)","2017 Jun 9","Almeida M, Pintacuda G, Masui O, Koseki Y, Gdula M, Cerase A, Brown D, Mould A, Innocent C, Nakayama M, Schermelleh L, Nesterova TB, Koseki H, Brockdorff N"
> "O88509-1","30468428","Targets and genomic constraints of ectopic Dnmt3b expression.","eLife","2018 Nov 23","Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A"
> "O88509-1","21666347","The Dnmt3b splice variant is specifically expressed in in vitro-manipulated blastocysts and their derivative ES cells.","The Journal of reproduction and development","2011 Oct","Horii T, Suetake I, Yanagisawa E, Morita S, Kimura M, Nagao Y, Imai H, Tajima S, Hatada I"
5142a5658,5660
> "Q9ER62-1","29973541","Transmembrane TNF and Partially TNFR1 Regulate TNFR2 Expression and Control Inflammation in Mycobacterial-Induced Pleurisy.","International journal of molecular sciences","2018 Jul 4","Uysal H, Chavez-Galan L, Vesin D, Blaser G, Benkhoucha M, Ryffel B, Quesniaux VFJ, Garcia I"
> "Q9QWH1-1","24091011","SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing.","Developmental cell","2013 Sep 30","Isono K, Endo TA, Ku M, Yamada D, Suzuki R, Sharif J, Ishikura T, Toyoda T, Bernstein BE, Koseki H"
> "Q9QWH1-1","23605804","Expression pattern and functional role of Phc2 during activation of helper T cells after antigenic stimulation.","In vitro cellular &amp; developmental biology. Animal","2013 May","Cho KW, Bae J, Lee SJ, Chun T"
5145,5147d5662
< "Q9JLB0-1","26496923","Immunohistochemical study of the membrane skeletal protein, membrane protein palmitoylated 6 (MPP6), in the mouse small intestine.","Histochemistry and cell biology","2016 Jan","Kamijo A, Saitoh Y, Ohno N, Ohno S, Terada N"
< "Q9JLB0-1","23306908","Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS.","Histochemistry and cell biology","2013 Aug","Terada N, Saitoh Y, Ohno N, Komada M, Yamauchi J, Ohno S"
< "Q9JLB0-1","22025680","Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves.","Molecular and cellular biology","2012 Jan","Terada N, Saitoh Y, Ohno N, Komada M, Saitoh S, Peles E, Ohno S"
5158a5674,5678
> "Q8BX22-1","22385656","Functional antagonism between Sall4 and Plzf defines germline progenitors.","Cell stem cell","2012 Mar 2","Hobbs RM, Fagoonee S, Papa A, Webster K, Altruda F, Nishinakamura R, Chai L, Pandolfi PP"
> "Q8BX22-1","17060609","Murine inner cell mass-derived lineages depend on Sall4 function.","Proceedings of the National Academy of Sciences of the United States of America","2006 Oct 31","Elling U, Klasen C, Eisenberger T, Anlag K, Treier M"
> "Q8BX22-1","16790473","The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.","Development (Cambridge, England)","2006 Aug","Sakaki-Yumoto M, Kobayashi C, Sato A, Fujimura S, Matsumoto Y, Takasato M, Kodama T, Aburatani H, Asashima M, Yoshida N, Nishinakamura R"
> "Q8BX22-1","16380715","Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.","Nature genetics","2006 Feb","Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG"
> "Q8BX22-1","12826753","Cloning and expression analysis of SALL4, the murine homologue of the gene mutated in Okihiro syndrome.","Cytogenetic and genome research","2002","Kohlhase J, Heinrich M, Liebers M, Frohlich Archangelo L, Reardon W, Kispert A"
5165a5686,5688
> "Q61985-1","30287392","Mechanisms controlling the multistage post-translational processing of endogenous Nrf1alpha/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits.","Toxicology and applied pharmacology","2018 Dec 1","Xiang Y, Wang M, Hu S, Qiu L, Yang F, Zhang Z, Yu S, Pi J, Zhang Y"
> "Q61985-1","30268580","Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor.","Toxicology and applied pharmacology","2018 Dec 1","Xiang Y, Halin J, Fan Z, Hu S, Wang M, Qiu L, Zhang Z, Mattjus P, Zhang Y"
> "Q61985-1","29935181","Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice.","Biochemical and biophysical research communications","2018 Sep 3","Hou Y, Liu Z, Zuo Z, Gao T, Fu J, Wang H, Xu Y, Liu D, Yamamoto M, Zhu B, Zhang Y, Andersen ME, Zhang Q, Pi J"
5168a5692
> "Q9CQG3-1","15950311","Immunohistochemical distribution of MIZIP and its co-expression with the Melanin-concentrating hormone receptor 1 in the adult rodent brain.","Brain research. Molecular brain research","2005 Sep 13","Francke F, Richter D, Bachner D"
5180,5183d5703
< "Q8BMT4-1","28459434","Mice deficient in NRROS show abnormal microglial development and neurological disorders.","Nature immunology","2017 Jun","Wong K, Noubade R, Manzanillo P, Ota N, Foreman O, Hackney JA, Friedman BA, Pappu R, Scearce-Levie K, Ouyang W"
< "Q8BMT4-1","26442864","NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-N:B and Reactive Oxygen Species Pathways.","Molecules and cells","2015 Oct","Kim JH, Kim K, Kim I, Seong S, Kim N"
< "Q8BMT4-1","24550525","Epigenetically modulated LRRC33 acts as a negative physiological regulator for multiple Toll-like receptors.","Journal of leukocyte biology","2014 Jul","Su X, Mei S, Liang X, Wang S, Liu J, Zhang Y, Bao Y, Chen Y, Che Y, Chunhua Zhao R, Zhang Z, Yang R"
< "Q8BMT4-1","24739962","NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.","Nature","2014 May 8","Noubade R, Wong K, Ota N, Rutz S, Eidenschenk C, Valdez PA, Ding J, Peng I, Sebrell A, Caplazi P, DeVoss J, Soriano RH, Sai T, Lu R, Modrusan Z, Hackney J, Ouyang W"
5188,5194d5707
< "O54804-1","26125130","The hepatic circadian clock regulates the choline kinase alpha gene through the BMAL1-REV-ERBalpha axis.","Chronobiology international","2015","Grechez-Cassiau A, Feillet C, Guerin S, Delaunay F"
< "O54804-1","20525991","Phosphatidylcholine biosynthesis during neuronal differentiation and its role in cell fate determination.","The Journal of biological chemistry","2010 Aug 13","Marcucci H, Paoletti L, Jackowski S, Banchio C"
< "O54804-1","20026284","Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse.","Biochimica et biophysica acta","2010 Apr","Wu G, Sher RB, Cox GA, Vance DE"
< "O54804-1","18029352","Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis.","The Journal of biological chemistry","2008 Jan 18","Wu G, Aoyama C, Young SG, Vance DE"
< "O54804-1","17728180","Induction of choline kinase alpha by carbon tetrachloride (CCl4) occurs via increased binding of c-jun to an AP-1 element.","Biochimica et biophysica acta","2007 Sep","Aoyama C, Ishidate K, Sugimoto H, Vance DE"
< "O54804-1","16490392","Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta.","Biochimica et biophysica acta","2006 Jan","Liao H, Aoyama C, Ishidate K, Teraoka H"
< "O54804-1","11964179","Expression and characterization of the active molecular forms of choline/ethanolamine kinase-alpha and -beta in mouse tissues, including carbon tetrachloride-induced liver.","The Biochemical journal","2002 May 1","Aoyama C, Ohtani A, Ishidate K"
5195a5709
> "P40237-1","29760437","CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22.","Experimental &amp; molecular medicine","2018 May 14","Koh HJ, Kim YR, Kim JS, Yun JS, Kim S, Kim SY, Jang K, Yang CS"
5201a5716
> "Q61473-1","11973269","Depletion of definitive gut endoderm in Sox17-null mutant mice.","Development (Cambridge, England)","2002 May","Kanai-Azuma M, Kanai Y, Gad JM, Tajima Y, Taya C, Kurohmaru M, Sanai Y, Yonekawa H, Yazaki K, Tam PP, Hayashi Y"
5209a5725,5728
> "Q9CXY9-1","9356492","The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase.","Proceedings of the National Academy of Sciences of the United States of America","1997 Nov 11","Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME"
> "Q9QYI5-3","21832061","Hsc70 protein interaction with soluble and fibrillar alpha-synuclein.","The Journal of biological chemistry","2011 Oct 7","Pemberton S, Madiona K, Pieri L, Kabani M, Bousset L, Melki R"
> "Q9QYI5-3","20395441","DNAJB2 expression in normal and diseased human and mouse skeletal muscle.","The American journal of pathology","2010 Jun","Claeys KG, Sozanska M, Martin JJ, Lacene E, Vignaud L, Stockholm D, Laforet P, Eymard B, Kichler A, Scherman D, Voit T, Israeli D"
> "Q9QYI5-3","16604191","Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.","The Journal of clinical investigation","2006 May","Borrell-Pages M, Canals JM, Cordelieres FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Neri C, Alberch J, Brouillet E, Saudou F, Humbert S"
5217,5219c5736
< "Q6KCD5-1","28041881","Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration.","Neuron","2017 Jan 18","van den Berg DLC, Azzarelli R, Oishi K, Martynoga B, Urban N, Dekkers DHW, Demmers JA, Guillemot F"
< "Q6KCD5-1","27606604","Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.","PLoS biology","2016 Sep","Santos R, Kawauchi S, Jacobs RE, Lopez-Burks ME, Choi H, Wikenheiser J, Hallgrimsson B, Jamniczky HA, Fraser SE, Lander AD, Calof AL"
< "Q6KCD5-1","19763162","Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome.","PLoS genetics","2009 Sep","Kawauchi S, Calof AL, Santos R, Lopez-Burks ME, Young CM, Hoang MP, Chua A, Lao T, Lechner MS, Daniel JA, Nussenzweig A, Kitzes L, Yokomori K, Hallgrimsson B, Lander AD"
---
> "P45700-1","21577142","Differential expression and function of alpha-mannosidase I in stimulated naive and memory CD4+ T cells.","Journal of immunotherapy (Hagerstown, Md. : 1997)","2011 Jun","Gebuhr I, Keeren K, Vogt K, Hoflich C, Appelt C, Schlieer U, Brandt C, Meisel C, Volk HD, Sawitzki B"
5221,5222d5737
< "Q9QXL2-1","29158259","Structural analyses of key features in the KANK1.KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex.","The Journal of biological chemistry","2018 Jan 5","Weng Z, Shang Y, Yao D, Zhu J, Zhang R"
< "Q9QXL2-1","22465342","Spatiotemporal expression pattern of KIF21A during normal embryonic development and in congenital fibrosis of the extraocular muscles type 1 (CFEOM1).","Gene expression patterns : GEP","2012 May-Jun","Desai J, Velo MP, Yamada K, Overman LM, Engle EC"
5227c5742,5745
< "P43006-1","29722912","Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice.","Glia","2018 Sep","Zhao Z, Hiraoka Y, Ogawa H, Tanaka K"
---
> "Q8BGN5-1","19738379","Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function.","Cytogenetic and genome research","2009","Grzmil P, Konietzko J, Boehm D, Holter SM, Aguilar-Pimentel A, Javaheri A, Kalaydjiev S, Adler T, Bolle I, Adham I, Dixkens C, Wolf S, Fuchs H, Gailus-Durner V, Wurst W, Ollert M, Busch DH, Schulz H, de Angelis MH, Burfeind P"
> "P63058-1","29753845","Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling.","Toxicology letters","2018 Sep 15","Yu Z, Han Y, Shen R, Huang K, Xu YY, Wang QN, Zhou SS, Xu DX, Tao FB"
> "P63058-1","29648626","Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function.","Endocrinology","2018 May 1","van der Spek AH, Surovtseva OV, Jim KK, van Oudenaren A, Brouwer MC, Vandenbroucke-Grauls CMJE, Leenen PJM, van de Beek D, Hernandez A, Fliers E, Boelen A"
> "Q6DIC6-1","15162511","Comparative expression analysis of the MAGED genes during embryogenesis and brain development.","Developmental dynamics : an official publication of the American Association of Anatomists","2004 Jun","Bertrand M, Huijbers I, Chomez P, De Backer O"
5232,5237d5749
< "Q5EE38-1","30189268","High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype.","Gene","2018 Dec 30","Sucularli C, Thomas P, Kocak H, White JS, O'Connor BC, Keegan CE"
< "Q5EE38-1","29386102","The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action.","Cell reports","2018 Jan 30","Grill S, Tesmer VM, Nandakumar J"
< "Q5EE38-1","24469404","TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1.","Molecular and cellular biology","2014 Apr","Frescas D, de Lange T"
< "Q5EE38-1","24316971","Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.","The Journal of clinical investigation","2014 Jan","Jones M, Osawa G, Regal JA, Weinberg DN, Taggart J, Kocak H, Friedman A, Ferguson DO, Keegan CE, Maillard I"
< "Q5EE38-1","17632522","Telomere protection by mammalian Pot1 requires interaction with Tpp1.","Nature structural &amp; molecular biology","2007 Aug","Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, Ye JZ, Keegan CE, de Lange T, Hammer GD"
< "Q5EE38-1","15537664","Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.","Human molecular genetics","2005 Jan 1","Keegan CE, Hutz JE, Else T, Adamska M, Shah SP, Kent AE, Howes JM, Beamer WG, Hammer GD"
5250a5763
> "Q62159-1","27269051","Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.","eLife","2016 Jun 8","Zhao B, Wu Z, Muller U"
5252,5257c5765,5775
< "Q80TJ7-1","29317619","Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway.","Nature communications","2018 Jan 9","Chen X, Wang S, Zhou Y, Han Y, Li S, Xu Q, Xu L, Zhu Z, Deng Y, Yu L, Song L, Chen AP, Song J, Takahashi E, He G, He L, Li W, Chen CD"
< "Q80TJ7-1","28485378","Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.","Nature communications","2017 May 9","Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K"
< "Q80TJ7-1","26866517","Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1.","Stem cells (Dayton, Ohio)","2016 Jun","Tang Y, Hong YZ, Bai HJ, Wu Q, Chen CD, Lang JY, Boheler KR, Yang HT"
< "Q80TJ7-1","25921086","The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload.","Experimental cell research","2015 Jul 1","Liu X, Wang X, Bi Y, Bu P, Zhang M"
< "Q80TJ7-1","16199551","Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate.","Journal of medical genetics","2005 Oct","Laumonnier F, Holbert S, Ronce N, Faravelli F, Lenzner S, Schwartz CE, Lespinasse J, Van Esch H, Lacombe D, Goizet C, Phan-Dinh Tuy F, van Bokhoven H, Fryns JP, Chelly J, Ropers HH, Moraine C, Hamel BC, Briault S"
< "Q3UEI1-1","21670265","Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.","Proceedings of the National Academy of Sciences of the United States of America","2011 Jun 28","Choi YH, Suzuki A, Hajarnis S, Ma Z, Chapin HC, Caplan MJ, Pontoglio M, Somlo S, Igarashi P"
---
> "Q91XQ5-1","27410685","Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis.","PloS one","2016","Suzuki K, Arumugam S, Yokoyama J, Kawauchi Y, Honda Y, Sato H, Aoyagi Y, Terai S, Okazaki K, Suzuki Y, Mizumoto S, Sugahara K, Atreya R, Neurath MF, Watanabe K, Hashiguchi T, Yoneyama H, Asakura H"
> "Q3UUG6-1","24729547","A dominant mutation in the stereocilia-expressing gene TBC1D24 is a probable cause for nonsyndromic hearing impairment.","Human mutation","2014 Jul","Zhang L, Hu L, Chai Y, Pang X, Yang T, Wu H"
> "Q3UUG6-1","20797691","A focal epilepsy and intellectual disability syndrome is due to a mutation in TBC1D24.","American journal of human genetics","2010 Sep 10","Corbett MA, Bahlo M, Jolly L, Afawi Z, Gardner AE, Oliver KL, Tan S, Coffey A, Mulley JC, Dibbens LM, Simri W, Shalata A, Kivity S, Jackson GD, Berkovic SF, Gecz J"
> "Q3UUG6-1","20727515","TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy.","American journal of human genetics","2010 Sep 10","Falace A, Filipello F, La Padula V, Vanni N, Madia F, De Pietri Tonelli D, de Falco FA, Striano P, Dagna Bricarelli F, Minetti C, Benfenati F, Fassio A, Zara F"
> "Q78JE5-1","26868148","SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.","Nature communications","2016 Feb 12","Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M"
> "Q61335-1","24139803","CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress.","Cell reports","2013 Oct 31","Namba T, Tian F, Chu K, Hwang SY, Yoon KW, Byun S, Hiraki M, Mandinova A, Lee SW"
> "Q63994-1","25320078","Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.","The Journal of biological chemistry","2014 Nov 28","Laubli H, Alisson-Silva F, Stanczak MA, Siddiqui SS, Deng L, Verhagen A, Varki N, Varki A"
> "Q63994-1","24227736","Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2013 Nov 13","Claude J, Linnartz-Gerlach B, Kudin AP, Kunz WS, Neumann H"
> "Q63994-1","17008544","CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.","Blood","2007 Feb 1","Orr SJ, Morgan NM, Elliott J, Burrows JF, Scott CJ, McVicar DW, Johnston JA"
> "Q63994-1","12773563","CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice.","Molecular and cellular biology","2003 Jun","Brinkman-Van der Linden EC, Angata T, Reynolds SA, Powell LD, Hedrick SM, Varki A"
> "P70365-1","30979869","Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis.","Nature communications","2019 Apr 12","Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K, Hinton A Jr, Yan X, Keogh JM, Henning E, Banton MC, Hendricks AE, Bochukova EG, Mistry V, Lawler KL, Liao L, Xu J, O'Rahilly S, Tong Q, Ines Barroso, O'Malley BW, Farooqi IS, Xu Y"
5264a5783
> "Q64700-1","28550162","Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.","The Journal of experimental medicine","2017 Jul 3","Kim E, Cheng Y, Bolton-Gillespie E, Cai X, Ma C, Tarangelo A, Le L, Jambhekar M, Raman P, Hayer KE, Wertheim G, Speck NA, Tong W, Viatour P"
5270a5790,5791
> "O55143-1","30299255","The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.","eLife","2018 Oct 9","Makarewich CA, Munir AZ, Schiattarella GG, Bezprozvannaya S, Raguimova ON, Cho EE, Vidal AH, Robia SL, Bassel-Duby R, Olson EN"
> "O55143-1","29986885","The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca(2+)-ATPase, is a major determinant of Ca(2+) alternans in intact mouse hearts.","The Journal of biological chemistry","2018 Aug 31","Sun B, Wei J, Zhong X, Guo W, Yao J, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Chen SRW"
5272a5794,5799
> "Q80VP1-1","25871009","Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.","Nature communications","2015 Mar 16","Chang B, Tessneer KL, McManus J, Liu X, Hahn S, Pasula S, Wu H, Song H, Chen Y, Cai X, Dong Y, Brophy ML, Rahman R, Ma JX, Xia L, Chen H"
> "Q80VP1-1","25314967","Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.","Science signaling","2014 Oct 14","Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H"
> "Q80VP1-1","23187125","Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.","The Journal of clinical investigation","2012 Dec","Pasula S, Cai X, Dong Y, Messa M, McManus J, Chang B, Liu X, Zhu H, Mansat RS, Yoon SJ, Hahn S, Keeling J, Saunders D, Ko G, Knight J, Newton G, Luscinskas F, Sun X, Towner R, Lupu F, Xia L, Cremona O, De Camilli P, Min W, Chen H"
> "Q80VP1-1","19666558","Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.","Proceedings of the National Academy of Sciences of the United States of America","2009 Aug 18","Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O"
> "Q80VP1-1","16574660","Clathrin-mediated endocytosis of the epithelial sodium channel. Role of epsin.","The Journal of biological chemistry","2006 May 19","Wang H, Traub LM, Weixel KM, Hawryluk MJ, Shah N, Edinger RS, Perry CJ, Kester L, Butterworth MB, Peters KW, Kleyman TR, Frizzell RA, Johnson JP"
> "Q6RKD8-1","16872596","Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.","Developmental biology","2006 Sep 1","Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW"
5283a5811
> "Q8K1M6-1","30475154","Drp1-dependent mitochondrial fission regulates p62-mediated autophagy in LPS-induced activated microglial cells.","Bioscience, biotechnology, and biochemistry","2019 Mar","Chae U, Kim HS, Lee HS, Lee SR, Lee DS"
5289,5291c5817
< "Q60651-1","27438766","Activating Receptors for Self-MHC Class I Enhance Effector Functions and Memory Differentiation of NK Cells during Mouse Cytomegalovirus Infection.","Immunity","2016 Jul 19","Nabekura T, Lanier LL"
< "Q60651-1","19247984","DAP10 associates with Ly49 receptors but contributes minimally to their expression and function in vivo.","European journal of immunology","2009 Apr","Tassi I, Le Friec G, Gilfillan S, Takai T, Yokoyama WM, Colonna M"
< "Q60651-1","19109149","Ly49D engagement on T lymphocytes induces TCR-independent activation and CD8 effector functions that control tumor growth.","Journal of immunology (Baltimore, Md. : 1950)","2009 Jan 1","Merck E, Voyle RB, MacDonald HR"
---
> "Q9QZS3-1","14641329","Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas.","Differentiation; research in biological diversity","2003 Oct","Yoshida T, Tokunaga A, Nakao K, Okano H"
5293a5820,5829
> "Q80VW7-1","21606955","Coordinate activation of inflammatory gene networks, alveolar destruction and neonatal death in AKNA deficient mice.","Cell research","2011 Nov","Ma W, Ortiz-Quintero B, Rangel R, McKeller MR, Herrera-Rodriguez S, Castillo EF, Schluns KS, Hall M, Zhang H, Suh WK, Okada H, Mak TW, Zhou Y, Blackburn MR, Martinez-Valdez H"
> "Q9CQ89-1","19645739","Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase.","The FEBS journal","2009 Aug","Liang D, Carvalho S, Bon S, Massoulie J"
> "Q9D2A5-1","28778797","Tisp40 deficiency attenuates renal ischemia reperfusion injury induced apoptosis of tubular epithelial cells.","Experimental cell research","2017 Oct 1","Qin C, Xiao C, Su Y, Zheng H, Xu T, Lu J, Luo P, Zhang J"
> "Q9D2A5-1","28618421","Identification of Tisp40 as an Essential Regulator of Renal Tubulointerstitial Fibrosis via TGF-beta/Smads Pathway.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2017","Xiao CC, Zhang J, Luo PC, Qin C, Du Y, Ning JZ, Zheng HZ"
> "Q9D2A5-1","25412305","Identification of Creb3l4 as an essential negative regulator of adipogenesis.","Cell death &amp; disease","2014 Nov 20","Kim TH, Jo SH, Choi H, Park JM, Kim MY, Nojima H, Kim JW, Ahn YH"
> "Q9D2A5-1","16925989","The enigma of ATCE1, an acrosome-associated transcription factor.","Developmental biology","2006 Oct 1","Gil S, Yosef D, Golan N, Don J"
> "Q9D2A5-1","16728718","Stage-specific expression of the Atce1/Tisp40alpha isoform of CREB3L4 in mouse spermatids.","Journal of andrology","2006 Sep-Oct","El-Alfy M, Azzi L, Lessard J, Lavergne E, Pelletier M, Labrie C"
> "Q9D2A5-1","16595651","Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.","The Journal of biological chemistry","2006 Jun 2","Nagamori I, Yomogida K, Adams PD, Sassone-Corsi P, Nojima H"
> "Q9D2A5-1","16107712","Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice.","Molecular and cellular biology","2005 Sep","Adham IM, Eck TJ, Mierau K, Muller N, Sallam MA, Paprotta I, Schubert S, Hoyer-Fender S, Engel W"
> "Q9D2A5-1","15938716","Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2005 Jun","Nagamori I, Yabuta N, Fujii T, Tanaka H, Yomogida K, Nishimune Y, Nojima H"
5297,5299c5833,5834
< "Q9R0N7-1","29957297","Synaptotagmin-7 controls the size of the reserve and resting pools of synaptic vesicles in hippocampal neurons.","Cell calcium","2018 Sep","Duran E, Montes MA, Jemal I, Satterfield R, Young S, Alvarez de Toledo G"
< "Q9R0N7-1","29771357","A promotive effect for halofuginone on membrane repair and synaptotagmin-7 levels in muscle cells of dysferlin-null mice.","Human molecular genetics","2018 Aug 15","Barzilai-Tutsch H, Dewulf M, Lamaze C, Butler Browne G, Pines M, Halevy O"
< "Q9R0N7-1","12071850","Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human.","The Biochemical journal","2002 Jul 1","Fukuda M, Ogata Y, Saegusa C, Kanno E, Mikoshiba K"
---
> "Q62315-1","30119689","JARID2 and the PRC2 complex regulate skeletal muscle differentiation through regulation of canonical Wnt signaling.","Epigenetics &amp; chromatin","2018 Aug 17","Adhikari A, Davie J"
> "Q62315-1","29891551","Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.","The Journal of biological chemistry","2018 Jul 27","Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y"
5301a5837,5846
> "Q5SWZ9-1","29113556","Phospholipase D Family Member 6 Is a Surface Marker for Enrichment of Undifferentiated Spermatogonia in Prepubertal Boars.","Stem cells and development","2018 Jan 1","Zhang P, Qin Y, Zheng Y, Zeng W"
> "Q5SWZ9-1","28749988","Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice.","PLoS genetics","2017 Jul","Inoue K, Ichiyanagi K, Fukuda K, Glinka M, Sasaki H"
> "Q5SWZ9-1","28115634","Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.","Nucleic acids research","2017 May 19","Kabayama Y, Toh H, Katanaya A, Sakurai T, Chuma S, Kuramochi-Miyagawa S, Saga Y, Nakano T, Sasaki H"
> "Q5SWZ9-1","27635761","Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division.","Molecular cell","2016 Sep 15","Adachi Y, Itoh K, Yamada T, Cerveny KL, Suzuki TL, Macdonald P, Frohman MA, Ramachandran R, Iijima M, Sesaki H"
> "Q5SWZ9-1","26711011","Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.","Molecular cell","2016 Jan 7","Zhang Y, Liu X, Bai J, Tian X, Zhao X, Liu W, Duan X, Shang W, Fan HY, Tong C"
> "Q5SWZ9-1","23064227","The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.","Nature","2012 Nov 8","Ipsaro JJ, Haase AD, Knott SR, Joshua-Tor L, Hannon GJ"
> "Q5SWZ9-1","22281006","Roles for the lipid-signaling enzyme MitoPLD in mitochondrial dynamics, piRNA biogenesis, and spermatogenesis.","BMB reports","2012 Jan","Gao Q, Frohman MA"
> "Q5SWZ9-1","21397848","piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling.","Developmental cell","2011 Mar 15","Huang H, Gao Q, Peng X, Choi SY, Sarma K, Ren H, Morris AJ, Frohman MA"
> "Q5SWZ9-1","21397847","MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline.","Developmental cell","2011 Mar 15","Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H"
> "Q8R516-1","15824097","Mind bomb-2 is an E3 ligase for Notch ligand.","The Journal of biological chemistry","2005 Jun 10","Koo BK, Yoon KJ, Yoo KW, Lim HS, Song R, So JH, Kim CH, Kong YY"
5316a5862
> "O08992-1","28418925","Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells.","Oncotarget","2017 Jun 13","Tae N, Lee S, Kim O, Park J, Na S, Lee JH"
5323a5870,5875
> "Q8BIF0-1","29791026","CD99L2 deficiency inhibits leukocyte entry into the central nervous system and ameliorates neuroinflammation.","Journal of leukocyte biology","2018 Oct","Samus M, Seelige R, Schafer K, Sorokin L, Vestweber D"
> "Q8BIF0-1","26321243","CD99-like 2 (CD99L2)-deficient mice are defective in the acute inflammatory response.","Experimental and molecular pathology","2015 Dec","Rutledge NS, Weber EW, Winger R, Tourtellotte WG, Park SH, Muller WA"
> "Q8BIF0-1","23338758","Effect of shRNA targeting mouse CD99L2 gene in a murine B cell lymphoma in vitro and in vivo.","Oncology reports","2013 Apr","Liu F, Zhang G, Liu F, Zhou X, Chen X, Han X, Wu Z, Zhao T"
> "Q8BIF0-1","23293350","Cutting edge: Endothelial-specific gene ablation of CD99L2 impairs leukocyte extravasation in vivo.","Journal of immunology (Baltimore, Md. : 1950)","2013 Feb 1","Seelige R, Natsch C, Marz S, Jing D, Frye M, Butz S, Vestweber D"
> "Q8BIF0-1","18163232","The murine CD99-related molecule CD99-like 2 (CD99L2) is an adhesion molecule involved in the inflammatory response.","Cell communication &amp; adhesion","2007 Sep-Oct","Schenkel AR, Dufour EM, Chew TW, Sorg E, Muller WA"
> "Q8BIF0-1","17344467","A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo.","Blood","2007 Jun 15","Bixel MG, Petri B, Khandoga AG, Khandoga A, Wolburg-Buchholz K, Wolburg H, Marz S, Krombach F, Vestweber D"
5328,5329c5880,5883
< "P47857-1","29655163","Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms.","Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie","2018 Jul","Ausina P, Da Silva D, Majerowicz D, Zancan P, Sola-Penna M"
< "P47857-1","27146165","Phosphofructokinase-1 Negatively Regulates Neurogenesis from Neural Stem Cells.","Neuroscience bulletin","2016 Jun","Zhang F, Qian X, Qin C, Lin Y, Wu H, Chang L, Luo C, Zhu D"
---
> "Q9JJC8-1","14508708","Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.","American journal of human genetics","2003 Oct","Chai JH, Locke DP, Greally JM, Knoll JH, Ohta T, Dunai J, Yavor A, Eichler EE, Nicholls RD"
> "Q8R5L3-1","20961651","The TGF-beta signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development.","Immunobiology","2011 Mar","Messler S, Kropp S, Episkopou V, Felici A, Wurthner J, Lemke R, Jerabek-Willemsen M, Willecke R, Scheu S, Pfeffer K, Wurthner JU"
> "Q8R5L3-1","20363736","Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence.","The Journal of biological chemistry","2010 May 28","Peralta ER, Martin BC, Edinger AL"
> "Q8R5L3-1","15110766","Spatio-temporal organization of Vam6P and SNAP on mouse spermatozoa and their involvement in sperm-zona pellucida interactions.","Biochemical and biophysical research communications","2004 May 21","Brahmaraju M, Shoeb M, Laloraya M, Kumar PG"
5333d5886
< "Q3USJ8-1","23437151","FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.","PloS one","2013","Cao H, Yin X, Cao Y, Jin Y, Wang S, Kong Y, Chen Y, Gao J, Heller S, Xu Z"
5342,5344c5895
< "Q9Z0H0-1","28887320","p53 gain-of-function mutations increase Cdc7-dependent replication initiation.","EMBO reports","2017 Nov","Datta A, Ghatak D, Das S, Banerjee T, Paul A, Butti R, Gorain M, Ghuwalewala S, Roychowdhury A, Alam SK, Das P, Chatterjee R, Dasgupta M, Panda CK, Kundu GC, Roychoudhury S"
< "Q9Z0H0-1","27401717","Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.","Nature communications","2016 Jul 12","Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H"
< "Q9Z0H0-1","24133205","Cell division cycle 7 mediates transforming growth factor-beta-induced smooth muscle maturation through activation of myocardin gene transcription.","The Journal of biological chemistry","2013 Nov 29","Shi N, Chen SY"
---
> "Q9CS42-1","26004865","PRPS2 Expression Correlates with Sertoli-Cell Only Syndrome and Inhibits the Apoptosis of TM4 Sertoli Cells.","The Journal of urology","2015 Nov","Lei B, Wan B, Peng J, Yang Y, Lv D, Zhou X, Shu F, Li F, Zhong L, Wu H, Mao X"
5354a5906
> "Q3TPJ7-1","24187134","Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner.","The Journal of biological chemistry","2013 Dec 13","Hofmeister-Brix A, Kollmann K, Langer S, Schultz J, Lenzen S, Baltrusch S"
5368c5920
< "Q3ULA2-1","30031111","beta-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.","Biochimica et biophysica acta. General subjects","2018 Oct","Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K"
---
> "O35654-1","22824807","Identification of Pold2 as a novel interaction partner of protein inhibitor of activated STAT2.","International journal of molecular medicine","2012 Oct","Zheng Y, Sheng S, Wang H, Jia X, Hu Y, Qian Y, Zhu Y, Wang J"
5377c5929,5932
< "Q5DTU0-1","27029000","XB130 deficiency enhances lipopolysaccharide-induced septic response and acute lung injury.","Oncotarget","2016 May 3","Toba H, Tomankova T, Wang Y, Bai X, Cho HR, Guan Z, Adeyi OA, Tian F, Keshavjee S, Liu M"
---
> "Q8K341-1","29703898","TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.","Nature communications","2018 Apr 27","Shah N, Kumar S, Zaman N, Pan CC, Bloodworth JC, Lei W, Streicher JM, Hempel N, Mythreye K, Lee NY"
> "Q8K341-1","28687926","ATAT1 is essential for regulation of homeostasis-retaining cellular responses in corticotrophs along hypothalamic-pituitary-adrenal axis.","Cell and tissue research","2017 Oct","Nakakura T, Suzuki T, Torii S, Asano-Hoshino A, Nekooki-Machida Y, Tanaka H, Arisawa K, Nishijima Y, Susa T, Okazaki T, Kiuchi Y, Hagiwara H"
> "Q8K341-1","27976998","Acetylated tubulin is essential for touch sensation in mice.","eLife","2016 Dec 13","Morley SJ, Qi Y, Iovino L, Andolfi L, Guo D, Kalebic N, Castaldi L, Tischer C, Portulano C, Bolasco G, Shirlekar K, Fusco CM, Asaro A, Fermani F, Sundukova M, Matti U, Reymond L, De Ninno A, Businaro L, Johnsson K, Lazzarino M, Ries J, Schwab Y, Hu J, Heppenstall PA"
> "Q8K341-1","23126280","Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of alpha-tubulin.","The Biochemical journal","2013 Feb 1","Yang W, Guo X, Thein S, Xu F, Sugii S, Baas PW, Radda GK, Han W"
5381a5937,5938
> "Q9Z139-1","30342492","Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target.","BMC cardiovascular disorders","2018 Oct 20","Heliste J, Jokilammi A, Paatero I, Chakroborty D, Stark C, Savunen T, Laaksonen M, Elenius K"
> "Q6PDG5-1","27392482","Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.","Molecular neurobiology","2017 Aug","Tuoc T, Dere E, Radyushkin K, Pham L, Nguyen H, Tonchev AB, Sun G, Ronnenberg A, Shi Y, Staiger JF, Ehrenreich H, Stoykova A"
5382a5940,5942
> "Q6PR54-1","30022158","53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polalpha-dependent fill-in.","Nature","2018 Aug","Mirman Z, Lottersberger F, Takai H, Kibe T, Gong Y, Takai K, Bianchi A, Zimmermann M, Durocher D, de Lange T"
> "Q6PR54-1","29719287","Downregulation of RIF1 Enhances Sensitivity to Platinum-Based Chemotherapy in Epithelial Ovarian Cancer (EOC) by Regulating Nucleotide Excision Repair (NER) Pathway.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2018","Liu YB, Mei Y, Tian ZW, Long J, Luo CH, Zhou HH"
> "Q9D513-1","24240703","MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination.","Nature communications","2013","Luo M, Yang F, Leu NA, Landaiche J, Handel MA, Benavente R, La Salle S, Wang PJ"
5385a5946,5947
> "Q8CI08-1","23077057","Microtubule plus-end tracking proteins SLAIN1/2 and ch-TOG promote axonal development.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2012 Oct 17","van der Vaart B, Franker MA, Kuijpers M, Hua S, Bouchet BP, Jiang K, Grigoriev I, Hoogenraad CC, Akhmanova A"
> "Q8CI08-1","21646404","SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase.","The Journal of cell biology","2011 Jun 13","van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelic S, Demmers J, Vorobjev I, Hoogenraad CC, Steinmetz MO, Akhmanova A"
5386a5949,5951
> "Q8C863-1","29925997","The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR.","Nature immunology","2018 Jul","Aki D, Li H, Zhang W, Zheng M, Elly C, Lee JH, Zou W, Liu YC"
> "Q8C863-1","29515120","Itch/beta-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.","Nature communications","2018 Mar 7","Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazza D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L"
> "Q8C863-1","28747490","Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.","EMBO reports","2017 Sep","Zhu K, Shan Z, Chen X, Cai Y, Cui L, Yao W, Wang Z, Shi P, Tian C, Lou J, Xie Y, Wen W"
5390a5956,5958
> "Q3UDK1-1","25992615","TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption.","PloS one","2015","Witwicka H, Jia H, Kutikov A, Reyes-Gutierrez P, Li X, Odgren PR"
> "Q3UDK1-1","18849341","FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.","The Journal of biological chemistry","2008 Dec 5","Sanada T, Takaesu G, Mashima R, Yoshida R, Kobayashi T, Yoshimura A"
> "Q3UDK1-1","16221674","FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.","The Journal of biological chemistry","2005 Dec 16","Mashima R, Saeki K, Aki D, Minoda Y, Takaki H, Sanada T, Kobayashi T, Aburatani H, Yamanashi Y, Yoshimura A"
5396a5965
> "A0A0B4J1F4-1","19605364","Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins.","The Journal of biological chemistry","2009 Sep 11","Patwari P, Chutkow WA, Cummings K, Verstraeten VL, Lammerding J, Schreiter ER, Lee RT"
5401,5405d5969
< "A2A8U2-1","28893537","Cytoplasmic transfer of heritable elements other than mtDNA from SAMP1 mice into mouse tumor cells suppresses their ability to form tumors in C57BL6 mice.","Biochemical and biophysical research communications","2017 Nov 4","Shimizu A, Tani H, Takibuchi G, Ishikawa K, Sakurazawa R, Inoue T, Hashimoto T, Nakada K, Takenaga K, Hayashi JI"
< "A2A8U2-1","28301579","A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis.","PloS one","2017","Menghini P, Di Martino L, Lopetuso LR, Corridoni D, Webster JC, Xin W, Arseneau KO, Lam M, Pizarro TT, Cominelli F"
< "A2A8U2-1","25051721","[Morphological changes of neurons and neuroglial cells in the brain of senescence-accelerated prone 1 (SAMP1) mice].","Arkhiv patologii","2014 Mar-Apr","Khudoerkov RM, Sal'kov VN, Sal'nikova OV, Sobolev VB"
< "A2A8U2-1","23583482","Impaired motor function in senescence-accelerated mouse prone 1 (SAMP1).","Brain research","2013 Jun 17","Aoyama Y, Kim TY, Yoshimoto T, Niimi K, Takahashi E, Itakura C"
< "A2A8U2-1","22349700","Samp1 is a component of TAN lines and is required for nuclear movement.","Journal of cell science","2012 Mar 1","Borrego-Pinto J, Jegou T, Osorio DS, Aurade F, Gorjanacz M, Koch B, Mattaj IW, Gomes ER"
5409a5974,5975
> "Q8C196-1","29801986","Conditional disruption of hepatic carbamoyl phosphate synthetase 1 in mice results in hyperammonemia without orotic aciduria and can be corrected by liver-directed gene therapy.","Molecular genetics and metabolism","2018 Aug","Khoja S, Nitzahn M, Hermann K, Truong B, Borzone R, Willis B, Rudd M, Palmer DJ, Ng P, Brunetti-Pierri N, Lipshutz GS"
> "E9Q5M6-1","28552195","Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella.","American journal of human genetics","2017 Jun 1","Tang S, Wang X, Li W, Yang X, Li Z, Liu W, Li C, Zhu Z, Wang L, Wang J, Zhang L, Sun X, Zhi E, Wang H, Li H, Jin L, Luo Y, Wang J, Yang S, Zhang F"
5411,5416c5977,5979
< "Q91WP0-1","28739878","Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 1","Banda NK, Acharya S, Scheinman RI, Mehta G, Takahashi M, Endo Y, Zhou W, Farrar CA, Sacks SH, Fujita T, Sekine H, Holers VM"
< "Q91WP0-1","28462915","Developmental activities of the complement pathway in migrating neurons.","Nature communications","2017 May 2","Gorelik A, Sapir T, Haffner-Krausz R, Olender T, Woodruff TM, Reiner O"
< "Q91WP0-1","27235854","Experimentally-induced anti-myeloperoxidase vasculitis does not require properdin, MASP-2 or bone marrow-derived C5.","The Journal of pathology","2016 Sep","Freeley SJ, Popat RJ, Parmar K, Kolev M, Hunt BJ, Stover CM, Schwaeble W, Kemper C, Robson MG"
< "Q91WP0-1","27577570","Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.","Journal of neuroinflammation","2016 Aug 30","Orsini F, Chrysanthou E, Dudler T, Cummings WJ, Takahashi M, Fujita T, Demopulos G, De Simoni MG, Schwaeble W"
< "Q91WP0-1","15826378","Production and purification of recombinants of mouse MASP-2 and sMAP.","Journal of endotoxin research","2005","Iwaki D, Fujita T"
< "Q91WP0-1","15672593","Organization of the MASP2 locus and its expression profile in mouse and rat.","Mammalian genome : official journal of the International Mammalian Genome Society","2004 Nov","Stover CM, Lynch NJ, Hanson SJ, Windbichler M, Gregory SG, Schwaeble WJ"
---
> "Q60631-1","30183074","Murine eosinophil development and allergic lung eosinophilia are largely dependent on the signaling adaptor GRB2.","European journal of immunology","2018 Nov","Willebrand R, Dietschmann A, Nitschke L, Krappmann S, Voehringer D"
> "Q60631-1","28964849","Grb2 regulates the proliferation of hematopoietic stem and progenitors cells.","Biochimica et biophysica acta. Molecular cell research","2017 Dec","Frelin C, Ofran Y, Ruston J, Hayun M, Derdikman Y, Khier Y, Rozales K, Brenner B, Iscove N, Pawson T, Louria-Hayon I"
> "Q60631-1","28455498","Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner.","Scientific reports","2017 Apr 28","Arya R, Dangi RS, Makwana PK, Kumar A, Upadhyay SK, Sundd M"
5425a5989
> "Q5SUQ9-1","22531781","CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.","The EMBO journal","2012 May 16","Gu P, Min JN, Wang Y, Huang C, Peng T, Chai W, Chang S"
5434,5437c5998,6013
< "Q91ZS8-1","28640668","Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mouse.","RNA biology","2017 Nov 2","Filippini A, Bonini D, Lacoux C, Pacini L, Zingariello M, Sancillo L, Bosisio D, Salvi V, Mingardi J, La Via L, Zalfa F, Bagni C, Barbon A"
< "Q91ZS8-1","28395340","Testicular adenosine to inosine RNA editing in the mouse is mediated by ADARB1.","Biology of reproduction","2017 Jan 1","Snyder EM, Licht K, Braun RE"
< "Q91ZS8-1","16382140","Altered RNA editing in mice lacking ADAR2 autoregulation.","Molecular and cellular biology","2006 Jan","Feng Y, Sansam CL, Singh M, Emeson RB"
< "Q8C6B2-1","22503686","cGMP-dependent protein kinase I is involved in neurite outgrowth via a Rho effector, rhotekin, in Neuro2A neuroblastoma cells.","Biochemical and biophysical research communications","2012 May 4","Yuasa K, Nagame T, Dohi M, Yanagita Y, Yamagami S, Nagahama M, Tsuji A"
---
> "Q9Z2W8-1","29704264","NF-Y-dependent regulation of glutamate receptor 4 expression and cell survival in cells of the oligodendrocyte lineage.","Glia","2018 Sep","Begum G, Otsu M, Ahmed U, Ahmed Z, Stevens A, Fulton D"
> "P28825-1","27628095","Deficiency of the DSPP-cleaving enzymes meprin alpha and meprin beta does not result in dentin malformation in mice.","Cell and tissue research","2017 Feb","Arnold P, Koopmann L, Peters F, Birkenfeld F, Goff SV, Damm T, Qin C, Moali C, Lucius R, Becker-Pauly C"
> "P28825-1","26491063","Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage.","Journal of biochemistry","2016 Mar","Sato Y, Kobayashi D, Kohno T, Kidani Y, Prox J, Becker-Pauly C, Hattori M"
> "Q80WQ6-1","30097271","iRhom2 promotes atherosclerosis through macrophage inflammation and induction of oxidative stress.","Biochemical and biophysical research communications","2018 Sep 10","Chaohui C, Wei H, Hongfeng W, Yueliang Z, Xiaoqin P, Pingli Z, Zhibing A"
> "Q80WQ6-1","29897336","FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.","eLife","2018 Jun 13","Kunzel U, Grieve AG, Meng Y, Sieber B, Cowley SA, Freeman M"
> "Q80WQ6-1","29897333","iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.","eLife","2018 Jun 13","Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, Clancy D, Brezinova J, Hu T, Bileck A, Gerner C, Bolado A, von Kriegsheim A, Martin SJ, Steinberg F, Strisovsky K, Adrain C"
> "A2ALU4-1","21248203","Shroom2 regulates contractility to control endothelial morphogenesis.","Molecular biology of the cell","2011 Mar 15","Farber MJ, Rizaldy R, Hildebrand JD"
> "A2ALU4-1","17666436","Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.","Journal of cell science","2007 Aug 15","Etournay R, Zwaenepoel I, Perfettini I, Legrain P, Petit C, El-Amraoui A"
> "Q8BND5-1","27581528","Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.","Free radical biology &amp; medicine","2016 Oct","Zhang L, Cheng Q, Zhang L, Wang Y, Merrill GF, Ilani T, Fass D, Arner ESJ, Zhang J"
> "Q8BND5-1","24475161","QSOX1 inhibits autophagic flux in breast cancer cells.","PloS one","2014","Poillet L, Pernodet N, Boyer-Guittaut M, Adami P, Borg C, Jouvenot M, Delage-Mourroux R, Despouy G"
> "Q8BND5-1","16160860","Cell-specific localization of the sulphydryl oxidase QSOX in rat peripheral tissues.","Cell and tissue research","2006 Jan","Tury A, Mairet-Coello G, Esnard-Feve A, Benayoun B, Risold PY, Griffond B, Fellmann D"
> "Q8BND5-1","12354420","Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells.","Journal of dermatological science","2002 Oct","Matsuba S, Suga Y, Ishidoh K, Hashimoto Y, Takamori K, Kominami E, Wilhelm B, Seitz J, Ogawa H"
> "Q9D5T7-1","29414051","Repair of exogenous DNA double-strand breaks promotes chromosome synapsis in SPO11-mutant mouse meiocytes, and is altered in the absence of HORMAD1.","DNA repair","2018 Mar","Carofiglio F, Sleddens-Linkels E, Wassenaar E, Inagaki A, van Cappellen WA, Grootegoed JA, Toth A, Baarends WM"
> "Q9D5T7-1","19686734","A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes.","Experimental cell research","2010 Jan 15","Fukuda T, Daniel K, Wojtasz L, Toth A, Hoog C"
> "Q9D5T7-1","19851446","Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase.","PLoS genetics","2009 Oct","Wojtasz L, Daniel K, Roig I, Bolcun-Filas E, Xu H, Boonsanay V, Eckmann CR, Cooke HJ, Jasin M, Keeney S, McKay MJ, Toth A"
> "Q9D5T7-1","15567723","Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain-containing protein.","Gene expression patterns : GEP","2004 Dec","Pangas SA, Yan W, Matzuk MM, Rajkovic A"
5441,5442c6017
< "Q9QYR6-1","28701415","Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain.","The Biochemical journal","2017 Aug 10","Xia Y, Shang Y, Zhang R, Zhu J"
< "Q9QYR6-1","26609151","Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Nov 25","Takei Y, Kikkawa YS, Atapour N, Hensch TK, Hirokawa N"
---
> "Q6P253-1","17330888","Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression.","Developmental dynamics : an official publication of the American Association of Anatomists","2007 Apr","Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM"
5446c6021
< "P63013-1","28366454","Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration.","Stem cell reports","2017 Apr 11","Wilk K, Yeh SA, Mortensen LJ, Ghaffarigarakani S, Lombardo CM, Bassir SH, Aldawood ZA, Lin CP, Intini G"
---
> "Q80U40-1","17855024","Structure and evolution of RIM-BP genes: identification of a novel family member.","Gene","2007 Nov 15","Mittelstaedt T, Schoch S"
5453a6029
> "Q8CIV3-1","23677168","Enpp2/Autotaxin in dermal papilla precursors is dispensable for hair follicle morphogenesis.","The Journal of investigative dermatology","2013 Oct","Grisanti L, Rezza A, Clavel C, Sennett R, Rendl M"
5455a6032,6039
> "P97820-1","30200638","RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis.","International journal of molecular sciences","2018 Sep 6","Peng HY, Liang YC, Tan TH, Chuang HC, Lin YJ, Lin JC"
> "Q6I6G8-1","29260931","Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.","Autophagy","2018","Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H"
> "Q6I6G8-1","27119228","NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.","Oncotarget","2016 May 24","Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, Zhang Y, Lu K, He F, Zhang L"
> "Q6I6G8-1","25555806","NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.","Cellular signalling","2015 Mar","Wei R, Qiu X, Wang S, Li Y, Wang Y, Lu K, Fu Y, Xing G, He F, Zhang L"
> "Q6I6G8-1","15284439","The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Dinudom A, Fotia AB, Lefkowitz RJ, Young JA, Kumar S, Cook DI"
> "Q80XB4-1","21998026","The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.","Genesis (New York, N.Y. : 2000)","2012 Apr","Krebs LT, Bradley CK, Norton CR, Xu J, Oram KF, Starling C, Deftos ML, Bevan MJ, Gridley T"
> "Q80XB4-1","21276443","Cardiac-specific NRAP overexpression causes right ventricular dysfunction in mice.","Experimental cell research","2011 May 1","Lu S, Crawford GL, Dore J, Anderson SA, Despres D, Horowits R"
> "Q80XB4-1","12789664","Genomic organization, alternative splicing, and expression of human and mouse N-RAP, a nebulin-related LIM protein of striated muscle.","Cell motility and the cytoskeleton","2003 Jul","Mohiddin SA, Lu S, Cardoso JP, Carroll S, Jha S, Horowits R, Fananapazir L"
5477,5478d6060
< "Q6P9K9-1","9856994","Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.","The Journal of biological chemistry","1998 Dec 25","Missler M, Hammer RE, Sudhof TC"
< "Q6P9K9-1","8163501","Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.","The Journal of biological chemistry","1994 Apr 22","Ushkaryov YA, Hata Y, Ichtchenko K, Moomaw C, Afendis S, Slaughter CA, Sudhof TC"
5493a6076
> "Q5SQX6-1","28692454","Phosphorylation of CYFIP2, a component of the WAVE-regulatory complex, regulates dendritic spine density and neurite outgrowth in cultured hippocampal neurons potentially by affecting the complex assembly.","Neuroreport","2017 Aug 16","Lee Y, Kim D, Ryu JR, Zhang Y, Kim S, Kim Y, Lee B, Sun W, Han K"
5498,5502c6081,6085
< "Q8VCS0-1","28951252","Sex-dependent alterations in motor and anxiety-like behavior of aged bacterial peptidoglycan sensing molecule 2 knockout mice.","Brain, behavior, and immunity","2018 Jan","Arentsen T, Khalid R, Qian Y, Diaz Heijtz R"
< "Q8VCS0-1","26332373","Functions of Peptidoglycan Recognition Proteins (Pglyrps) at the Ocular Surface: Bacterial Keratitis in Gene-Targeted Mice Deficient in Pglyrp-2, -3 and -4.","PloS one","2015","Gowda RN, Redfern R, Frikeche J, Pinglay S, Foster JW, Lema C, Cope L, Chakravarti S"
< "Q8VCS0-1","22615249","Role of mouse peptidoglycan recognition protein PGLYRP2 in the innate immune response to Salmonella enterica serovar Typhimurium infection in vivo.","Infection and immunity","2012 Aug","Lee J, Geddes K, Streutker C, Philpott DJ, Girardin SE"
< "Q8VCS0-1","22048773","Peptidoglycan recognition protein Pglyrp2 protects mice from psoriasis-like skin inflammation by promoting regulatory T cells and limiting Th17 responses.","Journal of immunology (Baltimore, Md. : 1950)","2011 Dec 1","Park SY, Gupta D, Hurwich R, Kim CH, Dziarski R"
< "Q8VCS0-1","15340057","Innate immune responses in peptidoglycan recognition protein L-deficient mice.","Molecular and cellular biology","2004 Sep","Xu M, Wang Z, Locksley RM"
---
> "Q9EST8-1","30224457","IkappaBzeta is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 2","Muller A, Hennig A, Lorscheid S, Grondona P, Schulze-Osthoff K, Hailfinger S, Kramer D"
> "Q9EST8-1","29670287","Electrophilic properties of itaconate and derivatives regulate the IkappaBzeta-ATF3 inflammatory axis.","Nature","2018 Apr","Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, Duncan D, Bregman H, Keskin A, Santeford A, Apte RS, Sehgal R, Johnson B, Amarasinghe GK, Soares MP, Satoh T, Akira S, Hai T, de Guzman Strong C, Auclair K, Roddy TP, Biller SA, Jovanovic M, Klechevsky E, Stewart KM, Randolph GJ, Artyomov MN"
> "Q9EST8-1","28740238","The resident pathobiont Staphylococcus xylosus in Nfkbiz-deficient skin accelerates spontaneous skin inflammation.","Scientific reports","2017 Jul 24","Kim Y, Lee YS, Yang JY, Lee SH, Park YY, Kweon MN"
> "Q9EST8-1","28391993","Sodium azide suppresses LPS-induced expression MCP-1 through regulating IkappaBzeta and STAT1 activities in macrophages.","Cellular immunology","2017 May","Park CY, Heo JN, Suk K, Lee WH"
> "Q9EST8-1","11086164","MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production.","FEBS letters","2000 Nov 17","Kitamura H, Kanehira K, Okita K, Morimatsu M, Saito M"
5506,5507c6089,6090
< "Q8BID6-1","22615130","Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage.","The Journal of experimental medicine","2012 Jun 4","Meredith MM, Liu K, Darrasse-Jeze G, Kamphorst AO, Schreiber HA, Guermonprez P, Idoyaga J, Cheong C, Yao KH, Niec RE, Nussenzweig MC"
< "Q8BID6-1","22615127","Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.","The Journal of experimental medicine","2012 Jun 4","Satpathy AT, KC W, Albring JC, Edelson BT, Kretzer NM, Bhattacharya D, Murphy TL, Murphy KM"
---
> "O09039-1","30254368","Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia.","Nature communications","2018 Sep 25","Balcerek J, Jiang J, Li Y, Jiang Q, Holdreith N, Singh B, Chandra V, Lv K, Ren JG, Rozenova K, Li W, Greenberg RA, Tong W"
> "Q6ZPK0-10","15325272","Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression.","Biochemical and biophysical research communications","2004 Sep 17","Iwase S, Januma A, Miyamoto K, Shono N, Honda A, Yanagisawa J, Baba T"
5508a6092,6096
> "Q8BSP2-1","27737961","Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability.","Genes &amp; development","2016 Oct 1","Woodward J, Taylor GC, Soares DC, Boyle S, Sie D, Read D, Chathoth K, Vukovic M, Tarrats N, Jamieson D, Campbell KJ, Blyth K, Acosta JC, Ylstra B, Arends MJ, Kranc KR, Jackson AP, Bickmore WA, Wood AJ"
> "Q8BSP2-1","25961503","Condensin confers the longitudinal rigidity of chromosomes.","Nature cell biology","2015 Jun","Houlard M, Godwin J, Metson J, Lee J, Hirano T, Nasmyth K"
> "Q8BSP2-1","25474630","Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.","PLoS genetics","2014 Dec","Nishide K, Hirano T"
> "Q8BSP2-1","22333158","Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1.","The FEBS journal","2012 Apr","Theodoratos A, Wilson LO, Gosling KM, Fahrer AM"
> "Q8BSP2-1","17640884","A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development.","Proceedings of the National Academy of Sciences of the United States of America","2007 Jul 24","Gosling KM, Makaroff LE, Theodoratos A, Kim YH, Whittle B, Rui L, Wu H, Hong NA, Kennedy GC, Fritz JA, Yates AL, Goodnow CC, Fahrer AM"
5510,5511d6097
< "O54714-1","27845432","Protein Inhibitor of Activated STAT3 Suppresses Oxidized LDL-induced Cell Responses during Atherosclerosis in Apolipoprotein E-deficient Mice.","Scientific reports","2016 Nov 15","Wang R, Zhang Y, Xu L, Lin Y, Yang X, Bai L, Chen Y, Zhao S, Fan J, Cheng X, Liu E"
< "O54714-1","25713074","Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).","The Journal of biological chemistry","2015 Apr 10","Siatecka M, Soni S, Planutis A, Bieker JJ"
5517,5518c6103,6106
< "Q60634-1","27993509","Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons.","Experimental neurology","2017 Mar","Bodrikov V, Pauschert A, Kochlamazashvili G, Stuermer CAO"
< "Q60634-1","26313572","Expression of Flotilin-2 and Acrosome Biogenesis Are Regulated by MiR-124 during Spermatogenesis.","PloS one","2015","Wu Y, Zhong A, Zheng H, Jiang M, Xia Z, Yu J, Chen L, Huang X"
---
> "Q4FZD7-1","21245385","Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression.","Molecular and cellular biology","2011 Mar","de Carcer G, Escobar B, Higuero AM, Garcia L, Anson A, Perez G, Mollejo M, Manning G, Melendez B, Abad-Rodriguez J, Malumbres M"
> "P55292-1","30115995","Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury.","Mucosal immunology","2018 Nov","Gross A, Pack LAP, Schacht GM, Kant S, Ungewiss H, Meir M, Schlegel N, Preisinger C, Boor P, Guldiken N, Krusche CA, Sellge G, Trautwein C, Waschke J, Heuser A, Leube RE, Strnad P"
> "P55292-1","28339476","Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling.","PloS one","2017","Brodehl A, Belke DD, Garnett L, Martens K, Abdelfatah N, Rodriguez M, Diao C, Chen YX, Gordon PM, Nygren A, Gerull B"
> "P55292-1","27834139","MicroRNA-130a Regulation of Desmocollin 2 in a Novel Model of Arrhythmogenic Cardiomyopathy.","MicroRNA (Shariqah, United Arab Emirates)","2017","Mazurek SR, Calway T, Harmon C, Farrell P, Kim GH"
5519a6108
> "Q9JHE7-1","10915772","Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.","Human molecular genetics","2000 Jul 22","Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J"
5521a6111,6113
> "Q3TKT4-1","30372823","Brahma-related gene 1 ameliorates the neuronal apoptosis and oxidative stress induced by oxygen-glucose deprivation/reoxygenation through activation of Nrf2/HO-1 signaling.","Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie","2018 Dec","Li F, Liang J, Tang D"
> "Q3TKT4-1","30049497","Brg1 deficiency in vascular endothelial cells blocks neutrophil recruitment and ameliorates cardiac ischemia-reperfusion injury in mice.","International journal of cardiology","2018 Oct 15","Zhang X, Liu S, Weng X, Zeng S, Yu L, Guo J, Xu Y"
> "Q3TKT4-1","30149919","Brg1 aggravates airway inflammation in asthma via inhibition of the PI3K/Akt/mTOR pathway.","Biochemical and biophysical research communications","2018 Sep 18","Zou W, Ding F, Niu C, Fu Z, Liu S"
5522a6115
> "P70429-1","28320969","Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration.","Proceedings of the National Academy of Sciences of the United States of America","2017 Apr 4","Estin ML, Thompson SB, Traxinger B, Fisher MH, Friedman RS, Jacobelli J"
5526,5527c6119
< "Q8CH20-1","17342728","A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family.","Molecular reproduction and development","2008 Feb","Hansen MA, Nielsen JE, Retelska D, Larsen N, Leffers H"
< "Q8CH20-1","15286030","Characterization of a novel postacrosomal perinuclear theca-specific protein, CYPT1.","Biology of reproduction","2004 Dec","Kitamura K, Iguchi N, Kaneko Y, Tanaka H, Nishimune Y"
---
> "Q80XU5-1","27329800","Changes in the expression of the type 2 diabetes-associated gene VPS13C in the beta-cell are associated with glucose intolerance in humans and mice.","American journal of physiology. Endocrinology and metabolism","2016 Aug 1","Mehta ZB, Fine N, Pullen TJ, Cane MC, Hu M, Chabosseau P, Meur G, Velayos-Baeza A, Monaco AP, Marselli L, Marchetti P, Rutter GA"
5532,5535d6123
< "Q61818-1","30275311","Early adolescent Rai1 reactivation reverses transcriptional and social interaction deficits in a mouse model of Smith-Magenis syndrome.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 16","Huang WH, Wang DC, Allen WE, Klope M, Hu H, Shamloo M, Luo L"
< "Q61818-1","27693255","Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.","Neuron","2016 Oct 19","Huang WH, Guenthner CJ, Xu J, Nguyen T, Schwarz LA, Wilkinson AW, Gozani O, Chang HY, Shamloo M, Luo L"
< "Q61818-1","25752576","Viral pseudo-enzymes activate RIG-I via deamidation to evade cytokine production.","Molecular cell","2015 Apr 2","He S, Zhao J, Song S, He X, Minassian A, Zhou Y, Zhang J, Brulois K, Wang Y, Cabo J, Zandi E, Liang C, Jung JU, Zhang X, Feng P"
< "Q61818-1","25127133","Dietary regimens modify early onset of obesity in mice haploinsufficient for Rai1.","PloS one","2014","Alaimo JT, Hahn NC, Mullegama SV, Elsea SH"
5551a6140
> "Q3URQ0-1","25936917","Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming.","Cell stem cell","2015 Jun 4","Ding J, Huang X, Shao N, Zhou H, Lee DF, Faiola F, Fidalgo M, Guallar D, Saunders A, Shliaha PV, Wang H, Waghray A, Papatsenko D, Sanchez-Priego C, Li D, Yuan Y, Lemischka IR, Shen L, Kelley K, Deng H, Shen X, Wang J"
5555d6143
< "Q99M96-1","15485929","Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.","Molecular and cellular biology","2004 Nov","Pal S, Vishwanath SN, Erdjument-Bromage H, Tempst P, Sif S"
5564a6153
> "Q9JM13-1","27820702","Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.","The Journal of clinical investigation","2016 Dec 1","Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ"
5568a6158
> "Q9DB70-1","29744594","NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2alpha.","Basic research in cardiology","2018 May 9","Zhou H, Wang J, Zhu P, Zhu H, Toan S, Hu S, Ren J, Chen Y"
5570a6161,6163
> "O88879-1","29596528","Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.","PloS one","2018","Tong H, Miyake Y, Mi-Ichi F, Iwakura Y, Hara H, Yoshida H"
> "O88879-1","27580417","microRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1.","Antioxidants &amp; redox signaling","2017 Apr 10","Lin HC, Liu SY, Yen EY, Li TK, Lai IR"
> "Q6PHZ2-1","28383548","miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2.","Cell death &amp; disease","2017 Apr 6","Zhang X, Wang C, Zhao J, Xu J, Geng Y, Dai L, Huang Y, Fu SC, Dai K, Zhang X"
5579a6173,6176
> "Q9QYY8-1","30213879","Functional differences of short and long isoforms of spastin harboring missense mutation.","Disease models &amp; mechanisms","2018 Sep 10","Plaud C, Joshi V, Kajevu N, Pous C, Curmi PA, Burgo A"
> "Q9QYY8-1","28392418","Spastin regulates VAMP7-containing vesicles trafficking in cortical neurons.","Biochimica et biophysica acta. Molecular basis of disease","2017 Jun","Plaud C, Joshi V, Marinello M, Pastre D, Galli T, Curmi PA, Burgo A"
> "Q9QYY8-1","27773584","Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination.","Neuron","2016 Nov 23","Brill MS, Kleele T, Ruschkies L, Wang M, Marahori NA, Reuter MS, Hausrat TJ, Weigand E, Fisher M, Ahles A, Engelhardt S, Bishop DL, Kneussel M, Misgeld T"
> "Q9QYY8-1","24065130","Amyloid-beta oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.","The EMBO journal","2013 Nov 13","Zempel H, Luedtke J, Kumar Y, Biernat J, Dawson H, Mandelkow E, Mandelkow EM"
5589a6187
> "Q9D824-1","16690743","Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.","Proceedings of the National Academy of Sciences of the United States of America","2006 May 23","Stover EH, Chen J, Folens C, Lee BH, Mentens N, Marynen P, Williams IR, Gilliland DG, Cools J"
5595a6194
> "P97329-1","30006548","KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development.","Nature communications","2018 Jul 13","Geng A, Qiu R, Murai K, Liu J, Wu X, Zhang H, Farhoodi H, Duong N, Jiang M, Yee JK, Tsark W, Lu Q"
5608,5615c6207,6216
< "Q8BUG5-1","28963059","CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus.","Neuroscience letters","2017 Nov 20","Yagishita K, Suzuki R, Mizuno S, Katoh-Semba R, Sadakata T, Sano Y, Furuichi T, Shinoda Y"
< "Q8BUG5-1","25754523","Lack of stress responses to long-term effects of corticosterone in Caps2 knockout mice.","Scientific reports","2015 Mar 10","Mishima Y, Shinoda Y, Sadakata T, Kojima M, Wakana S, Furuichi T"
< "Q8BUG5-1","25437547","Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.","Cell reports","2014 Nov 6","Nguyen Truong CQ, Nestvogel D, Ratai O, Schirra C, Stevens DR, Brose N, Rhee J, Rettig J"
< "Q8BUG5-1","22111578","Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.","The FEBS journal","2012 Feb","Sadakata T, Sekine Y, Oka M, Itakura M, Takahashi M, Furuichi T"
< "Q8BUG5-1","21173225","Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network.","Proceedings of the National Academy of Sciences of the United States of America","2011 Jan 4","Shinoda Y, Sadakata T, Nakao K, Katoh-Semba R, Kinameri E, Furuya A, Yanagawa Y, Hirase H, Furuichi T"
< "Q8BUG5-1","20302894","Ca(2+)-dependent activator protein for secretion 2 and autistic-like phenotypes.","Neuroscience research","2010 Jul","Sadakata T, Furuichi T"
< "Q8BUG5-1","19238500","Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.","Cerebellum (London, England)","2009 Sep","Sadakata T, Furuichi T"
< "Q8BUG5-1","11846421","Cloning, characterization, and expression of calcyphosine 2, a novel human gene encoding an EF-hand Ca(2+)-binding protein.","Biochemical and biophysical research communications","2002 Feb 22","Wang S, Chen JZ, Zhang Z, Huang Q, Gu S, Ying K, Xie Y, Mao Y"
---
> "Q11131-1","27591321","Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene.","Journal of immunology (Baltimore, Md. : 1950)","2016 Oct 15","Pink M, Ratsch BA, Mardahl M, Durek P, Polansky JK, Karl M, Baumgrass R, Wallner S, Cadenas C, Gianmoena K, Floess S, Chen W, Nordstroem K, Tierling S, Olek S, Walter J, Hamann A, Syrbe U"
> "Q8BWJ4-1","28888937","Low density lipoprotein receptor class A domain containing 4 (LDLRAD4) promotes tumorigenesis of hepatic cancer cells.","Experimental cell research","2017 Nov 15","Liu Z, Huo X, Zhao S, Yang J, Shi W, Jing L, Li W, Li Y, Ma L, Gao Y, Diao A"
> "Q8BVZ1-1","29378767","Perilipin 5 Deletion Unmasks an Endoplasmic Reticulum Stress-Fibroblast Growth Factor 21 Axis in Skeletal Muscle.","Diabetes","2018 Apr","Montgomery MK, Mokhtar R, Bayliss J, Parkington HC, Suturin VM, Bruce CR, Watt MJ"
> "Q8BVZ1-1","28919478","Atorvastatin reduces lipid accumulation in the liver by activating protein kinase A-mediated phosphorylation of perilipin 5.","Biochimica et biophysica acta. Molecular and cell biology of lipids","2017 Dec","Gao X, Nan Y, Zhao Y, Yuan Y, Ren B, Sun C, Cao K, Yu M, Feng X, Ye J"
> "Q8BVZ1-1","17234449","LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues.","Biochimica et biophysica acta","2007 Feb","Dalen KT, Dahl T, Holter E, Arntsen B, Londos C, Sztalryd C, Nebb HI"
> "Q8BVZ1-1","16571721","MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha.","The Journal of biological chemistry","2006 May 19","Yamaguchi T, Matsushita S, Motojima K, Hirose F, Osumi T"
> "O54785-1","28669900","Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain.","Neuropharmacology","2017 Oct","Yang X, He G, Zhang X, Chen L, Kong Y, Xie W, Jia Z, Liu WT, Zhou Z"
> "Q91ZM2-1","29180441","Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Apr","Jiang L, Su H, Keogh JM, Chen Z, Henning E, Wilkinson P, Goodyer I, Farooqi IS, Rui L"
> "Q91ZM2-1","27217487","4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls beta-Cell Mass.","Diabetes","2016 Aug","Blandino-Rosano M, Scheys JO, Jimenez-Palomares M, Barbaresso R, Bender AS, Yanagiya A, Liu M, Rui L, Sonenberg N, Bernal-Mizrachi E"
> "Q91ZM2-1","18247337","PSM/SH2B1 splice variants: critical role in src catalytic activation and the resulting STAT3s-mediated mitogenic response.","Journal of cellular biochemistry","2008 May 1","Zhang M, Deng Y, Riedel H"
5620a6222,6223
> "Q9WVH4-1","30718226","Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets.","Cellular and molecular gastroenterology and hepatology","2019","Penrose HM, Cable C, Heller S, Ungerleider N, Nakhoul H, Baddoo M, Hartono AB, Lee SB, Burow ME, Flemington EF, Crawford SE, Savkovic SD"
> "Q9WVH4-1","11875118","Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins.","Molecular endocrinology (Baltimore, Md.)","2002 Mar","Richards JS, Sharma SC, Falender AE, Lo YH"
5628a6232,6233
> "O08791-1","29869132","The caudo-ventral pallium is a novel pallial domain expressing Gdf10 and generating Ebf3-positive neurons of the medial amygdala.","Brain structure &amp; function","2018 Sep","Ruiz-Reig N, Andres B, Lamonerie T, Theil T, Fairen A, Studer M"
> "O08791-1","29563184","Stem cell niche-specific Ebf3 maintains the bone marrow cavity.","Genes &amp; development","2018 Mar 1","Seike M, Omatsu Y, Watanabe H, Kondoh G, Nagasawa T"
5634,5638c6239,6246
< "Q8BZN4-1","30446657","NUAK2 is a critical YAP target in liver cancer.","Nature communications","2018 Nov 16","Yuan WC, Pepe-Mooney B, Galli GG, Dill MT, Huang HT, Hao M, Wang Y, Liang H, Calogero RA, Camargo FD"
< "Q8BZN4-1","29298809","Sucrose Nonfermenting-Related Kinase Regulates Both Adipose Inflammation and Energy Homeostasis in Mice and Humans.","Diabetes","2018 Mar","Li J, Feng B, Nie Y, Jiao P, Lin X, Huang M, An R, He Q, Zhou HE, Salomon A, Sigrist KS, Wu Z, Liu S, Xu H"
< "Q8BZN4-1","26690705","The AMPK-related kinase SNARK regulates muscle mass and myocyte survival.","The Journal of clinical investigation","2016 Feb","Lessard SJ, Rivas DA, So K, Koh HJ, Queiroz AL, Hirshman MF, Fielding RA, Goodyear LJ"
< "Q8BZN4-1","20713714","Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle.","Proceedings of the National Academy of Sciences of the United States of America","2010 Aug 31","Koh HJ, Toyoda T, Fujii N, Jung MM, Rathod A, Middelbeek RJ, Lessard SJ, Treebak JT, Tsuchihara K, Esumi H, Richter EA, Wojtaszewski JF, Hirshman MF, Goodyear LJ"
< "Q8BZN4-1","18307533","Susceptibility of Snark-deficient mice to azoxymethane-induced colorectal tumorigenesis and the formation of aberrant crypt foci.","Cancer science","2008 Apr","Tsuchihara K, Ogura T, Fujioka R, Fujii S, Kuga W, Saito M, Ochiya T, Ochiai A, Esumi H"
---
> "P58283-1","27995769","TRIAD3/RNF216 mutations associated with Gordon Holmes syndrome lead to synaptic and cognitive impairments via Arc misregulation.","Aging cell","2017 Apr","Husain N, Yuan Q, Yen YC, Pletnikova O, Sally DQ, Worley P, Bichler Z, Shawn Je H"
> "P58283-1","28154178","Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216.","The Journal of biological chemistry","2017 Mar 10","Kumazoe M, Nakamura Y, Yamashita M, Suzuki T, Takamatsu K, Huang Y, Bae J, Yamashita S, Murata M, Yamada S, Shinoda Y, Yamaguchi W, Toyoda Y, Tachibana H"
> "P58283-1","25484083","Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination.","Autophagy","2014","Xu C, Feng K, Zhao X, Huang S, Cheng Y, Qian L, Wang Y, Sun H, Jin M, Chuang TH, Zhang Y"
> "P20181-1","29549646","NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation.","Molecular neurobiology","2018 Nov","Lin YJ, Hsin IL, Sun HS, Lin S, Lai YL, Chen HY, Chen TY, Chen YP, Shen YT, Wu HM"
> "Q9CZ44-1","27540115","Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 6","Al Ghouleh I, Meijles DN, Mutchler S, Zhang Q, Sahoo S, Gorelova A, Henrich Amaral J, Rodriguez AI, Mamonova T, Song GJ, Bisello A, Friedman PA, Cifuentes-Pagano ME, Pagano PJ"
> "Q9CZ44-1","23429921","NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.","Diabetologia","2013 May","Koulajian K, Desai T, Liu GC, Ivovic A, Patterson JN, Tang C, El-Benna J, Joseph JW, Scholey JW, Giacca A"
> "Q9CZ44-1","18403597","Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.","The American journal of pathology","2008 May","Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, Caito S, Adenuga D, Rahman I"
> "Q9CZ44-1","14988733","Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.","The EMBO journal","2004 Mar 10","Dreveny I, Kondo H, Uchiyama K, Shaw A, Zhang X, Freemont PS"
5647d6254
< "Q9CWV1-1","22771120","MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination.","Molecular cell","2012 Aug 24","Lutzmann M, Grey C, Traver S, Ganier O, Maya-Mendoza A, Ranisavljevic N, Bernex F, Nishiyama A, Montel N, Gavois E, Forichon L, de Massy B, Mechali M"
5648a6256,6260
> "Q6HA09-1","28911209","Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida.","Molecular human reproduction","2017 Sep 1","Korschgen H, Kuske M, Karmilin K, Yiallouros I, Balbach M, Floehr J, Wachten D, Jahnen-Dechent W, Stocker W"
> "Q6HA09-1","28114310","A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice.","PLoS genetics","2017 Jan","Xiong B, Zhao Y, Beall S, Sadusky AB, Dean J"
> "Q6HA09-1","22472438","Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy.","The Journal of cell biology","2012 Apr 2","Burkart AD, Xiong B, Baibakov B, Jimenez-Movilla M, Dean J"
> "Q6HA09-1","22206759","Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization.","Developmental biology","2012 Mar 1","Sachdev M, Mandal A, Mulders S, Digilio LC, Panneerdoss S, Suryavathi V, Pires E, Klotz KL, Hermens L, Herrero MB, Flickinger CJ, van Duin M, Herr JC"
> "Q6HA09-1","22275110","Astacin-like metallo-endopeptidase is dynamically expressed in embryonic stem cells and embryonic epithelium during morphogenesis.","Developmental dynamics : an official publication of the American Association of Anatomists","2012 Mar","Acloque H, Lavial F, Pain B"
5650a6263,6267
> "Q8VCS0-1","28951252","Sex-dependent alterations in motor and anxiety-like behavior of aged bacterial peptidoglycan sensing molecule 2 knockout mice.","Brain, behavior, and immunity","2018 Jan","Arentsen T, Khalid R, Qian Y, Diaz Heijtz R"
> "Q8VCS0-1","26332373","Functions of Peptidoglycan Recognition Proteins (Pglyrps) at the Ocular Surface: Bacterial Keratitis in Gene-Targeted Mice Deficient in Pglyrp-2, -3 and -4.","PloS one","2015","Gowda RN, Redfern R, Frikeche J, Pinglay S, Foster JW, Lema C, Cope L, Chakravarti S"
> "Q8VCS0-1","22615249","Role of mouse peptidoglycan recognition protein PGLYRP2 in the innate immune response to Salmonella enterica serovar Typhimurium infection in vivo.","Infection and immunity","2012 Aug","Lee J, Geddes K, Streutker C, Philpott DJ, Girardin SE"
> "Q8VCS0-1","22048773","Peptidoglycan recognition protein Pglyrp2 protects mice from psoriasis-like skin inflammation by promoting regulatory T cells and limiting Th17 responses.","Journal of immunology (Baltimore, Md. : 1950)","2011 Dec 1","Park SY, Gupta D, Hurwich R, Kim CH, Dziarski R"
> "Q8VCS0-1","15340057","Innate immune responses in peptidoglycan recognition protein L-deficient mice.","Molecular and cellular biology","2004 Sep","Xu M, Wang Z, Locksley RM"
5659a6277
> "Q80TY0-1","15252009","A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis.","The Journal of biological chemistry","2004 Sep 17","Kamioka Y, Fukuhara S, Sawa H, Nagashima K, Masuda M, Matsuda M, Mochizuki N"
5662,5663d6279
< "Q80ZD8-1","26240432","AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.","Schizophrenia bulletin","2016 Jan","Peltola MA, Kuja-Panula J, Liuhanen J, Voikar V, Piepponen P, Hiekkalinna T, Taira T, Lauri SE, Suvisaari J, Kulesskaya N, Paunio T, Rauvala H"
< "Q80ZD8-1","22056818","AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.","EMBO reports","2011 Dec 1","Peltola MA, Kuja-Panula J, Lauri SE, Taira T, Rauvala H"
5666,5668d6281
< "Q6URW6-1","27385019","Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.","PLoS genetics","2016 Jul","Wang JJ, Rau C, Avetisyan R, Ren S, Romay MC, Stolin G, Gong KW, Wang Y, Lusis AJ"
< "Q6URW6-1","28101381","Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice.","Neural plasticity","2016","Fu X, Zhang L, Jin Y, Sun X, Zhang A, Wen Z, Zhou Y, Xia M, Gao J"
< "Q6URW6-1","12598534","Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages.","The Journal of biological chemistry","2003 Apr 25","Buxton DB, Golomb E, Adelstein RS"
5674,5681c6287
< "Q5RJI5-1","27251228","Structure and inhibition analysis of the mouse SAD-B C-terminal fragment.","Bioscience, biotechnology, and biochemistry","2016 Oct","Ma H, Wu JX, Wang J, Wang ZX, Wu JW"
< "Q5RJI5-1","27626661","SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression.","Cell reports","2016 Sep 13","Mochida S, Hida Y, Tanifuji S, Hagiwara A, Hamada S, Abe M, Ma H, Yasumura M, Kitajima I, Sakimura K, Ohtsuka T"
< "Q5RJI5-1","26444684","SAD-B kinase regulates pre-synaptic vesicular dynamics at hippocampal Schaffer collateral synapses and affects contextual fear memory.","Journal of neurochemistry","2016 Jan","Watabe AM, Nagase M, Hagiwara A, Hida Y, Tsuji M, Ochiai T, Kato F, Ohtsuka T"
< "Q5RJI5-1","17482548","LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.","Cell","2007 May 4","Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F"
< "Q5RJI5-1","15705853","Mammalian SAD kinases are required for neuronal polarization.","Science (New York, N.Y.)","2005 Feb 11","Kishi M, Pan YA, Crump JG, Sanes JR"
< "Q62048-1","29928894","High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle.","Metabolism: clinical and experimental","2018 Oct","Vastolo V, Nettore IC, Ciccarelli M, Albano L, Raciti GA, Longo M, Beguinot F, Ungaro P"
< "Q62048-1","27426254","Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice.","Scientific reports","2016 Jul 18","Perruolo G, Viggiano D, Fiory F, Cassese A, Nigro C, Liotti A, Miele C, Beguinot F, Formisano P"
< "Q62048-1","19917132","Deletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities.","BMC neuroscience","2009 Nov 16","Ramos JW, Townsend DA, Piarulli D, Kolata S, Light K, Hale G, Matzel LD"
---
> "Q8VHI4-1","11832226","A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF.","Neuron","2002 Jan 31","Tao X, West AE, Chen WG, Corfas G, Greenberg ME"
5707,5709d6312
< "Q8C7R7-1","25497096","Rfx6 maintains the functional identity of adult pancreatic beta cells.","Cell reports","2014 Dec 24","Piccand J, Strasser P, Hodson DJ, Meunier A, Ye T, Keime C, Birling MC, Rutter GA, Gradwohl G"
< "Q8C7R7-1","20148032","Rfx6 directs islet formation and insulin production in mice and humans.","Nature","2010 Feb 11","Smith SB, Qu HQ, Taleb N, Kishimoto NY, Scheel DW, Lu Y, Patch AM, Grabs R, Wang J, Lynn FC, Miyatsuka T, Mitchell J, Seerke R, Desir J, Vanden Eijnden S, Abramowicz M, Kacet N, Weill J, Renard ME, Gentile M, Hansen I, Dewar K, Hattersley AT, Wang R, Wilson ME, Johnson JD, Polychronakos C, German MS"
< "Q8C7R7-1","20040487","Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.","Development (Cambridge, England)","2010 Jan","Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G"
5712,5714d6314
< "Q5SRY7-1","30031111","beta-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.","Biochimica et biophysica acta. General subjects","2018 Oct","Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K"
< "Q5SRY7-1","26240281","S6 Kinase- and beta-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.","Molecular and cellular biology","2015 Oct","Nakagawa T, Araki T, Nakagawa M, Hirao A, Unno M, Nakayama K"
< "Q5SRY7-1","18782782","The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2.","Journal of biochemistry","2008 Nov","Ohsaki K, Oishi K, Kozono Y, Nakayama K, Nakayama KI, Ishida N"
5717,5719d6316
< "Q9JIM1-1","30408123","Changes in aortic reactivity associated with the loss of equilibrative nucleoside transporter 1 (ENT1) in mice.","PloS one","2018","Best KA, Bone DB, Vilas G, Gros R, Hammond JR"
< "Q9JIM1-1","28069792","Targeting ENT1 and adenosine tone for the treatment of Huntington's disease.","Human molecular genetics","2017 Feb 1","Kao YH, Lin MS, Chen CM, Wu YR, Chen HM, Lai HL, Chern Y, Lin CJ"
< "Q9JIM1-1","12062437","PKC regulation of the human equilibrative nucleoside transporter, hENT1.","FEBS letters","2002 Apr 24","Coe I, Zhang Y, McKenzie T, Naydenova Z"
5729a6327,6329
> "O54965-1","26197965","Enhanced metastasis in RNF13 knockout mice is mediated by a reduction in GM-CSF levels.","Protein &amp; cell","2015 Oct","Cheng H, Wang A, Meng J, Zhang Y, Zhu D"
> "O54965-1","24563216","Accelerated regeneration of the skeletal muscle in RNF13-knockout mice is mediated by macrophage-secreted IL-4/IL-6.","Protein &amp; cell","2014 Mar","Meng J, Zou X, Wu R, Zhong R, Zhu D, Zhang Y"
> "O54965-1","22890573","E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex.","Cellular and molecular life sciences : CMLS","2013 Jan","Zhang Q, Li Y, Zhang L, Yang N, Meng J, Zuo P, Zhang Y, Chen J, Wang L, Gao X, Zhu D"
5731,5735d6330
< "Q8R317-1","27928652","Enhanced Proteostasis in Post-ischemic Stroke Mouse Brains by Ubiquilin-1 Promotes Functional Recovery.","Cellular and molecular neurobiology","2017 Oct","Liu Y, Qiao F, Wang H"
< "Q8R317-1","28420763","Reduced body weight gain in ubiquilin-1 transgenic mice is associated with increased expression of energy-sensing proteins.","Physiological reports","2017 Apr","Qiao F, Longley KR, Feng S, Schnack S, Gao H, Li Y, Schlenker EH, Wang H"
< "Q8R317-1","28598849","Overexpression of Ubiquilin-1 Alleviates Alzheimer's Disease-Caused Cognitive and Motor Deficits and Reduces Amyloid-beta Accumulation in Mice.","Journal of Alzheimer's disease : JAD","2017","Adegoke OO, Qiao F, Liu Y, Longley K, Feng S, Wang H"
< "Q8R317-1","19148225","PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation.","EMBO reports","2009 Feb","N'Diaye EN, Kajihara KK, Hsieh I, Morisaki H, Debnath J, Brown EJ"
< "Q8R317-1","15004330","Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins.","Journal of Alzheimer's disease : JAD","2004 Feb","Massey LK, Mah AL, Ford DL, Miller J, Liang J, Doong H, Monteiro MJ"
5740,5745d6334
< "Q925T6-1","29170386","Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages.","Nature communications","2017 Nov 23","Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall MA, Fisher RP, Hu X, Chinenov Y, Rogatsky I"
< "Q925T6-1","28978486","GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.","Cell reports","2017 Oct 3","Pfennig S, Foss F, Bissen D, Harde E, Treeck JC, Segarra M, Acker-Palmer A"
< "Q925T6-1","28063882","Mice lacking GRIP1/2 show increased social interactions and enhanced phosphorylation at GluA2-S880.","Behavioural brain research","2017 Mar 15","Han M, Mejias R, Chiu SL, Rose R, Adamczyk A, Huganir R, Wang T"
< "Q925T6-1","27941904","The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility.","Scientific reports","2016 Dec 12","Wang Y, Wu Z, Luo H, Peng J, Raelson J, Ehret GB, Munroe PB, Stoyanova E, Qin Z, Cloutier G, Bradley WE, Wu T, Shen JZ, Hu S, Wu J"
< "Q925T6-1","15507123","GRIP1tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2004 Nov","Nakata A, Ito T, Nagata M, Hori S, Sekimizu K"
< "Q925T6-1","11983858","Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1.","Proceedings of the National Academy of Sciences of the United States of America","2002 May 14","Bladt F, Tafuri A, Gelkop S, Langille L, Pawson T"
5749,5759d6337
< "Q8C9B9-1","28330622","DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells.","Stem cell reports","2017 Apr 11","Futterer A, de Celis J, Navajas R, Almonacid L, Gutierrez J, Talavera-Gutierrez A, Pacios-Bras C, Bernascone I, Martin-Belmonte F, Martinez-A C"
< "Q8C9B9-1","25825751","Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice.","Proceedings of the National Academy of Sciences of the United States of America","2015 Apr 14","Villares R, Gutierrez J, Futterer A, Trachana V, Gutierrez del Burgo F, Martinez-A C"
< "Q8C9B9-1","24667272","Dido3-dependent HDAC6 targeting controls cilium size.","Nature communications","2014 Mar 25","Sanchez de Diego A, Alonso Guerrero A, Martinez-A C, van Wely KH"
< "Q8C9B9-1","24347171","The death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal.","The Journal of biological chemistry","2014 Feb 21","Liu Y, Kim H, Liang J, Lu W, Ouyang B, Liu D, Songyang Z"
< "Q8C9B9-1","19557426","Synaptonemal complex assembly and H3K4Me3 demethylation determine DIDO3 localization in meiosis.","Chromosoma","2009 Oct","Prieto I, Kouznetsova A, Futterer A, Trachana V, Leonardo E, Alonso Guerrero A, Cano Gamero M, Pacios-Bras C, Leh H, Buckle M, Garcia-Gallo M, Kremer L, Serrano A, Roncal F, Albar JP, Barbero JL, Martinez-A C, van Wely KH"
< "Q8C9B9-1","17299043","Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability.","Proceedings of the National Academy of Sciences of the United States of America","2007 Feb 20","Trachana V, van Wely KH, Guerrero AA, Futterer A, Martinez-A C"
< "Q8C9B9-1","16127461","Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms.","The Journal of clinical investigation","2005 Sep","Futterer A, Campanero MR, Leonardo E, Criado LM, Flores JM, Hernandez JM, San Miguel JF, Martinez-A C"
< "Q61584-1","30770808","Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy.","Nature communications","2019 Feb 15","Estan MC, Fernandez-Nunez E, Zaki MS, Esteban MI, Donkervoort S, Hawkins C, Caparros-Martin JA, Saade D, Hu Y, Bolduc V, Chao KR, Nevado J, Lamuedra A, Largo R, Herrero-Beaumont G, Regadera J, Hernandez-Chico C, Tizzano EF, Martinez-Glez V, Carvajal JJ, Zong R, Nelson DL, Otaify GA, Temtamy S, Aglan M, Issa M, Bonnemann CG, Lapunzina P, Yoon G, Ruiz-Perez VL"
< "Q61584-1","30397356","Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.","Nature medicine","2018 Dec","Sun L, Xie C, Wang G, Wu Y, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C"
< "Q61584-1","29730159","FXR deletion in hepatocytes does not affect the severity of alcoholic liver disease in mice.","Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver","2018 Oct","Zhang M, Kong B, Huang M, Wan R, Armstrong LE, Schumacher JD, Rizzolo D, Chow MD, Lee YH, Guo GL"
< "Q61584-1","11178106","Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblast.","BMC genetics","2000","Dube M, Huot ME, Khandjian EW"
5760a6339
> "P97946-1","29632070","Histone deacetylase 4 shapes neuronal morphology via a mechanism involving regulation of expression of vascular endothelial growth factor D.","The Journal of biological chemistry","2018 May 25","Litke C, Bading H, Mauceri D"
5761a6341,6343
> "Q8C6K9-1","21477648","Differential and restricted expression of novel collagen VI chains in mouse.","Matrix biology : journal of the International Society for Matrix Biology","2011 May","Gara SK, Grumati P, Squarzoni S, Sabatelli P, Urciuolo A, Bonaldo P, Paulsson M, Wagener R"
> "Q8C6K9-1","18400749","Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI).","The Journal of biological chemistry","2008 Jul 18","Fitzgerald J, Rich C, Zhou FH, Hansen U"
> "Q8C6K9-1","18276594","Three novel collagen VI chains with high homology to the alpha3 chain.","The Journal of biological chemistry","2008 Apr 18","Gara SK, Grumati P, Urciuolo A, Bonaldo P, Kobbe B, Koch M, Paulsson M, Wagener R"
5765d6346
< "Q9JHH2-1","29178985","A complementary role for tetraspanin superfamily member TSSC6 and ADP purinergic P2Y12 receptor in platelets.","Thrombosis research","2018 Jan","Makkawi M, Howells D, Wright MD, Jackson DE"
5768,5771d6348
< "Q63994-1","25320078","Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.","The Journal of biological chemistry","2014 Nov 28","Laubli H, Alisson-Silva F, Stanczak MA, Siddiqui SS, Deng L, Verhagen A, Varki N, Varki A"
< "Q63994-1","24227736","Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2013 Nov 13","Claude J, Linnartz-Gerlach B, Kudin AP, Kunz WS, Neumann H"
< "Q63994-1","17008544","CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.","Blood","2007 Feb 1","Orr SJ, Morgan NM, Elliott J, Burrows JF, Scott CJ, McVicar DW, Johnston JA"
< "Q63994-1","12773563","CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice.","Molecular and cellular biology","2003 Jun","Brinkman-Van der Linden EC, Angata T, Reynolds SA, Powell LD, Hedrick SM, Varki A"
5773a6351,6353
> "Q9ERS5-1","27859053","B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.","European journal of immunology","2017 Feb","Jayachandran N, Landego I, Hou S, Alessi DR, Marshall AJ"
> "Q9ERS5-1","22777911","Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.","European journal of immunology","2012 Oct","Landego I, Jayachandran N, Wullschleger S, Zhang TT, Gibson IW, Miller A, Alessi DR, Marshall AJ"
> "Q62432-1","30651315","Uterine double-conditional inactivation of Smad2 and Smad3 in mice causes endometrial dysregulation, infertility, and uterine cancer.","Proceedings of the National Academy of Sciences of the United States of America","2019 Feb 26","Kriseman M, Monsivais D, Agno J, Masand RP, Creighton CJ, Matzuk MM"
5785a6366
> "Q8VDT1-1","15607332","SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose.","Life sciences","2005 Jan 14","Tazawa S, Yamato T, Fujikura H, Hiratochi M, Itoh F, Tomae M, Takemura Y, Maruyama H, Sugiyama T, Wakamatsu A, Isogai T, Isaji M"
5788,5789c6369,6370
< "Q9CY57-1","20688955","Fetal globin expression is regulated by Friend of Prmt1.","Blood","2010 Nov 18","van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S"
< "Q9CY57-1","19858291","Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.","Molecular and cellular biology","2010 Jan","van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S"
---
> "Q8BH60-1","20958966","PIST regulates the intracellular trafficking and plasma membrane expression of cadherin 23.","BMC cell biology","2010 Oct 19","Xu Z, Oshima K, Heller S"
> "Q8BH60-1","12149515","Lack of acrosome formation in mice lacking a Golgi protein, GOPC.","Proceedings of the National Academy of Sciences of the United States of America","2002 Aug 20","Yao R, Ito C, Natsume Y, Sugitani Y, Yamanaka H, Kuretake S, Yanagida K, Sato A, Toshimori K, Noda T"
5791,5795d6371
< "Q9EST8-1","30224457","IkappaBzeta is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 2","Muller A, Hennig A, Lorscheid S, Grondona P, Schulze-Osthoff K, Hailfinger S, Kramer D"
< "Q9EST8-1","29670287","Electrophilic properties of itaconate and derivatives regulate the IkappaBzeta-ATF3 inflammatory axis.","Nature","2018 Apr","Bambouskova M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, Korenfeld D, Mathyer ME, Kim H, Huang LH, Duncan D, Bregman H, Keskin A, Santeford A, Apte RS, Sehgal R, Johnson B, Amarasinghe GK, Soares MP, Satoh T, Akira S, Hai T, de Guzman Strong C, Auclair K, Roddy TP, Biller SA, Jovanovic M, Klechevsky E, Stewart KM, Randolph GJ, Artyomov MN"
< "Q9EST8-1","28740238","The resident pathobiont Staphylococcus xylosus in Nfkbiz-deficient skin accelerates spontaneous skin inflammation.","Scientific reports","2017 Jul 24","Kim Y, Lee YS, Yang JY, Lee SH, Park YY, Kweon MN"
< "Q9EST8-1","28391993","Sodium azide suppresses LPS-induced expression MCP-1 through regulating IkappaBzeta and STAT1 activities in macrophages.","Cellular immunology","2017 May","Park CY, Heo JN, Suk K, Lee WH"
< "Q9EST8-1","11086164","MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production.","FEBS letters","2000 Nov 17","Kitamura H, Kanehira K, Okita K, Morimatsu M, Saito M"
5805,5806c6381,6383
< "Q8C5L3-1","24200330","Identification of Ccr4-not complex components as regulators of transition from partial to genuine induced pluripotent stem cells.","Stem cells and development","2014 Sep 15","Kamon M, Katano M, Hiraki-Kamon K, Hishida T, Nakachi Y, Mizuno Y, Okazaki Y, Suzuki A, Hirasaki M, Ueda A, Nishimoto M, Kato H, Okuda A"
< "Q8C5L3-1","22367759","Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation.","Stem cells (Dayton, Ohio)","2012 May","Zheng X, Dumitru R, Lackford BL, Freudenberg JM, Singh AP, Archer TK, Jothi R, Hu G"
---
> "Q62418-1","22450813","The mammalian actin-binding protein 1 is critical for spreading and intraluminal crawling of neutrophils under flow conditions.","Journal of immunology (Baltimore, Md. : 1950)","2012 May 1","Hepper I, Schymeinsky J, Weckbach LT, Jakob SM, Frommhold D, Sixt M, Laschinger M, Sperandio M, Walzog B"
> "P17047-1","30048497","Inhibitors of lysosomal function or serum starvation in control or LAMP2 deficient cells do not modify the cellular levels of Parkinson disease-associated DJ-1/PARK 7 protein.","PloS one","2018","Sanchez-Lanzas R, Castano JG"
> "P17047-1","30068868","The Major Lysosomal Membrane Proteins LAMP-1 and LAMP-2 Participate in Differentiation of C2C12 Myoblasts.","Biological &amp; pharmaceutical bulletin","2018","Sakane H, Akasaki K"
5809a6387,6392
> "Q0VGM9-1","29290468","Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe.","Cell","2018 Jan 25","Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton SJ"
> "Q0VGM9-1","24115439","RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.","Science (New York, N.Y.)","2013 Oct 11","Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H, Boulton SJ"
> "Q0VGM9-1","22593209","RTEL1 contributes to DNA replication and repair and telomere maintenance.","Molecular biology of the cell","2012 Jul","Uringa EJ, Lisaingo K, Pickett HA, Brind'Amour J, Rohde JH, Zelensky A, Essers J, Lansdorp PM"
> "O35136-1","26611261","Abeta-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.","Nature communications","2015 Nov 27","Leshchyns'ka I, Liew HT, Shepherd C, Halliday GM, Stevens CH, Ke YD, Ittner LM, Sytnyk V"
> "O35136-1","25875008","OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor.","PloS one","2015","Deleyrolle L, Sabourin JC, Rothhut B, Fujita H, Guichet PO, Teigell M, Ripoll C, Chauvet N, Perrin F, Mamaeva D, Noda T, Mori K, Yoshihara Y, Hugnot JP"
> "O35136-1","25632147","Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Jan 28","Sheng L, Leshchyns'ka I, Sytnyk V"
5812,5817c6395,6397
< "P38532-1","30316516","NRF2 and HSF1 coordinately regulate heme oxygenase-1 expression.","Biochemical and biophysical research communications","2018 Nov 17","Inouye S, Hatori Y, Kubo T, Saito S, Kitamura H, Akagi R"
< "P38532-1","24855652","Novel isoforms of heat shock transcription factor 1, HSF1gammaalpha and HSF1gammabeta, regulate chaperone protein gene transcription.","The Journal of biological chemistry","2014 Jul 18","Neueder A, Achilli F, Moussaoui S, Bates GP"
< "Q8BWY7-1","23643525","Characterization of the GufA subfamily member SLC39A11/Zip11 as a zinc transporter.","The Journal of nutritional biochemistry","2013 Oct","Yu Y, Wu A, Zhang Z, Yan G, Zhang F, Zhang L, Shen X, Hu R, Zhang Y, Zhang K, Wang F"
< "Q91ZM2-1","29180441","Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Apr","Jiang L, Su H, Keogh JM, Chen Z, Henning E, Wilkinson P, Goodyer I, Farooqi IS, Rui L"
< "Q91ZM2-1","27217487","4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls beta-Cell Mass.","Diabetes","2016 Aug","Blandino-Rosano M, Scheys JO, Jimenez-Palomares M, Barbaresso R, Bender AS, Yanagiya A, Liu M, Rui L, Sonenberg N, Bernal-Mizrachi E"
< "Q91ZM2-1","18247337","PSM/SH2B1 splice variants: critical role in src catalytic activation and the resulting STAT3s-mediated mitogenic response.","Journal of cellular biochemistry","2008 May 1","Zhang M, Deng Y, Riedel H"
---
> "Q8C7R7-1","25497096","Rfx6 maintains the functional identity of adult pancreatic beta cells.","Cell reports","2014 Dec 24","Piccand J, Strasser P, Hodson DJ, Meunier A, Ye T, Keime C, Birling MC, Rutter GA, Gradwohl G"
> "Q8C7R7-1","20148032","Rfx6 directs islet formation and insulin production in mice and humans.","Nature","2010 Feb 11","Smith SB, Qu HQ, Taleb N, Kishimoto NY, Scheel DW, Lu Y, Patch AM, Grabs R, Wang J, Lynn FC, Miyatsuka T, Mitchell J, Seerke R, Desir J, Vanden Eijnden S, Abramowicz M, Kacet N, Weill J, Renard ME, Gentile M, Hansen I, Dewar K, Hattersley AT, Wang R, Wilson ME, Johnson JD, Polychronakos C, German MS"
> "Q8C7R7-1","20040487","Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.","Development (Cambridge, England)","2010 Jan","Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G"
5821d6400
< "Q9Z2Y3-1","12176012","An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.","Biochemical and biophysical research communications","2002 Aug 23","Saito H, Kimura M, Inanobe A, Ohe T, Kurachi Y"
5824,5825d6402
< "Q8C078-1","28981105","Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration.","Cell death &amp; disease","2017 Oct 5","Racioppi L, Lento W, Huang W, Arvai S, Doan PL, Harris JR, Marcon F, Nakaya HI, Liu Y, Chao N"
< "Q8C078-1","14586002","Loss of Ca2+/calmodulin kinase kinase beta affects the formation of some, but not all, types of hippocampus-dependent long-term memory.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2003 Oct 29","Peters M, Mizuno K, Ris L, Angelo M, Godaux E, Giese KP"
5828a6406,6414
> "Q8BR86-1","29362445","Abnormal behaviours relevant to neurodevelopmental disorders in Kirrel3-knockout mice.","Scientific reports","2018 Jan 23","Hisaoka T, Komori T, Kitamura T, Morikawa Y"
> "Q8BR86-1","28815295","Loss of Kirrel family members alters glomerular structure and synapse numbers in the accessory olfactory bulb.","Brain structure &amp; function","2018 Jan","Brignall AC, Raja R, Phen A, Prince JEA, Dumontier E, Cloutier JF"
> "Q8BR86-1","28670619","Examining Hippocampal Mossy Fiber Synapses by 3D Electron Microscopy in Wildtype and Kirrel3 Knockout Mice.","eNeuro","2017 May-Jun","Martin EA, Woodruff D, Rawson RL, Williams ME"
> "Q8BR86-1","28621431","Adhesion molecule Kirrel3/Neph2 is required for the elongated shape of myocytes during skeletal muscle differentiation.","The International journal of developmental biology","2017","Tamir-Livne Y, Mubariki R, Bengal E"
> "Q8BR86-1","18752272","Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles.","The Journal of comparative neurology","2008 Nov 1","Komori T, Gyobu H, Ueno H, Kitamura T, Senba E, Morikawa Y"
> "Q8BR86-1","18022324","Expression of mKirre in the developing sensory pathways: its close apposition to nephrin-expressing cells.","Neuroscience","2007 Dec 19","Morikawa Y, Komori T, Hisaoka T, Ueno H, Kitamura T, Senba E"
> "Q8BR86-1","16874800","Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis.","The Journal of comparative neurology","2006 Oct 1","Gerke P, Benzing T, Hohne M, Kispert A, Frotscher M, Walz G, Kretz O"
> "Q8BR86-1","15908127","Expression of mKirre, a mammalian homolog of Drosophila kirre, in the developing and adult mouse brain.","Neuroscience","2005","Tamura S, Morikawa Y, Hisaoka T, Ueno H, Kitamura T, Senba E"
> "Q8BR86-1","12665856","A stromal cell-derived membrane protein that supports hematopoietic stem cells.","Nature immunology","2003 May","Ueno H, Sakita-Ishikawa M, Morikawa Y, Nakano T, Kitamura T, Saito M"
5829a6416,6419
> "P70704-1","27287255","Aberrant hippocampal Atp8a1 levels are associated with altered synaptic strength, electrical activity, and autistic-like behavior.","Biochimica et biophysica acta","2016 Sep","Kerr DJ, Marsillo A, Guariglia SR, Budylin T, Sadek R, Menkes S, Chauhan A, Wen GY, McCloskey DP, Wieraszko A, Banerjee P"
> "P70704-1","22007859","Atp8a1 deficiency is associated with phosphatidylserine externalization in hippocampus and delayed hippocampus-dependent learning.","Journal of neurochemistry","2012 Jan","Levano K, Punia V, Raghunath M, Debata PR, Curcio GM, Mogha A, Purkayastha S, McCloskey D, Fata J, Banerjee P"
> "P70704-1","17239457","Isolation, sequencing, and functional analysis of the TATA-less murine ATPase II promoter and structural analysis of the ATPase II gene.","Biochimica et biophysica acta","2007 Jan","Sobocki T, Jayman F, Sobocka MB, Marmur JD, Banerjee P"
> "P70704-1","14975727","A novel aminophospholipid transporter exclusively expressed in spermatozoa is required for membrane lipid asymmetry and normal fertilization.","Developmental biology","2004 Mar 1","Wang L, Beserra C, Garbers DL"
5832,5837d6421
< "Q3UTH8-1","30087324","Developmental seizures and mortality result from reducing GABAA receptor alpha2-subunit interaction with collybistin.","Nature communications","2018 Aug 7","Hines RM, Maric HM, Hines DJ, Modgil A, Panzanelli P, Nakamura Y, Nathanson AJ, Cross A, Deeb T, Brandon NJ, Davies P, Fritschy JM, Schindelin H, Moss SJ"
< "Q3UTH8-1","29069083","RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of alpha2 GABAA receptors.","PLoS genetics","2017 Oct","de Groot C, Floriou-Servou A, Tsai YC, Fruh S, Kohler M, Parkin G, Schwerdel C, Bosshard G, Kaila K, Fritschy JM, Tyagarajan SK"
< "Q3UTH8-1","25082542","A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.","The EMBO journal","2014 Sep 17","Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N"
< "Q3UTH8-1","19236916","Increased network excitability and impaired induction of long-term potentiation in the dentate gyrus of collybistin-deficient mice in vivo.","Molecular and cellular neurosciences","2009 May","Jedlicka P, Papadopoulos T, Deller T, Betz H, Schwarzacher SW"
< "Q3UTH8-1","17690689","Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice.","The EMBO journal","2007 Sep 5","Papadopoulos T, Korte M, Eulenburg V, Kubota H, Retiounskaia M, Harvey RJ, Harvey K, O'Sullivan GA, Laube B, Hulsmann S, Geiger JR, Betz H"
< "Q3UTH8-1","16616186","The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor.","Journal of molecular biology","2006 May 26","Xiang S, Kim EY, Connelly JJ, Nassar N, Kirsch J, Winking J, Schwarz G, Schindelin H"
5841a6426,6430
> "O70293-1","30576947","Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and beta-arrestin 2 in inflammatory macrophages.","Molecular immunology","2019 Feb","Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ"
> "O70293-1","28939643","Role of G protein-coupled receptor kinase-6 in Escherichia coli lung infection model in mice.","Physiological genomics","2017 Nov 1","Lee T, Packiriswamy N, Lee E, Lucas PC, McCabe LR, Parameswaran N"
> "O70293-1","28457871","Dendritic Cells Interpret Haptotactic Chemokine Gradients in a Manner Governed by Signal-to-Noise Ratio and Dependent on GRK6.","Current biology : CB","2017 May 8","Schwarz J, Bierbaum V, Vaahtomeri K, Hauschild R, Brown M, de Vries I, Leithner A, Reversat A, Merrin J, Tarrant T, Bollenbach T, Sixt M"
> "O70293-1","12032308","Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.","Proceedings of the National Academy of Sciences of the United States of America","2002 May 28","Fong AM, Premont RT, Richardson RM, Yu YR, Lefkowitz RJ, Patel DD"
> "Q812A3-1","19028694","Identification and characterization of a novel gene, dapr, involved in skeletal muscle differentiation and protein kinase B signaling.","The Journal of biological chemistry","2009 Jan 16","Virtanen C, Paris J, Takahashi M"
5842a6432,6434
> "Q9ESZ8-1","31011227","Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug.","Nature neuroscience","2019 May","Barak B, Zhang Z, Liu Y, Nir A, Trangle SS, Ennis M, Levandowski KM, Wang D, Quast K, Boulting GL, Li Y, Bayarsaihan D, He Z, Feng G"
> "Q9ESZ8-1","29568691","Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams-Beuren syndrome and autism spectrum disorder.","Brain and behavior","2018 Jan","Martin LA, Iceberg E, Allaf G"
> "Q9ESZ8-1","27194223","Generation of a mouse model for a conditional inactivation of Gtf2i allele.","Genesis (New York, N.Y. : 2000)","2016 Jul","Enkhmandakh B, Stoddard C, Mack K, He W, Kaback D, Yee SP, Bayarsaihan D"
5845d6436
< "P63137-1","30013074","Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation.","Translational psychiatry","2018 Jul 17","Yeung RK, Xiang ZH, Tsang SY, Li R, Ho TYC, Li Q, Hui CK, Sham PC, Qiao MQ, Xue H"
5847c6438,6440
< "Q8BZQ2-1","17616516","CRISPLD2: a novel NSCLP candidate gene.","Human molecular genetics","2007 Sep 15","Chiquet BT, Lidral AC, Stal S, Mulliken JB, Moreno LM, Arcos-Burgos M, Valencia-Ramirez C, Blanton SH, Hecht JT"
---
> "Q9JLB0-1","26496923","Immunohistochemical study of the membrane skeletal protein, membrane protein palmitoylated 6 (MPP6), in the mouse small intestine.","Histochemistry and cell biology","2016 Jan","Kamijo A, Saitoh Y, Ohno N, Ohno S, Terada N"
> "Q9JLB0-1","23306908","Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS.","Histochemistry and cell biology","2013 Aug","Terada N, Saitoh Y, Ohno N, Komada M, Yamauchi J, Ohno S"
> "Q9JLB0-1","22025680","Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves.","Molecular and cellular biology","2012 Jan","Terada N, Saitoh Y, Ohno N, Komada M, Saitoh S, Peles E, Ohno S"
5853,5854d6445
< "Q61907-1","28291718","Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria.","Molecular genetics and metabolism","2017 Apr","Jacobs RL, Jiang H, Kennelly JP, Orlicky DJ, Allen RH, Stabler SP, Maclean KN"
< "Q61907-1","28159867","Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase.","Journal of lipid research","2017 Apr","van der Veen JN, Lingrell S, Gao X, Takawale A, Kassiri Z, Vance DE, Jacobs RL"
5856,5857d6446
< "Q80U63-1","30136162","NR4A1 Promotes Cerebral Ischemia Reperfusion Injury by Repressing Mfn2-Mediated Mitophagy and Inactivating the MAPK-ERK-CREB Signaling Pathway.","Neurochemical research","2018 Oct","Zhang Z, Yu J"
< "Q80U63-1","15297672","Structural basis of mitochondrial tethering by mitofusin complexes.","Science (New York, N.Y.)","2004 Aug 6","Koshiba T, Detmer SA, Kaiser JT, Chen H, McCaffery JM, Chan DC"
5871,5872d6459
< "Q80W68-1","29717104","Overexpression of Kin of IRRE-Like Protein 1 (KIRREL) in Gastric Cancer and Its Clinical Prognostic Significance.","Medical science monitor : international medical journal of experimental and clinical research","2018 May 2","Zhang MJ, Hong YY, Li N"
< "Q80W68-1","12538735","Alternatively used promoters and distinct elements direct tissue-specific expression of nephrin.","Journal of the American Society of Nephrology : JASN","2003 Feb","Beltcheva O, Kontusaari S, Fetissov S, Putaala H, Kilpelainen P, Hokfelt T, Tryggvason K"
5877a6465,6466
> "Q99LJ7-1","25762510","RC/BTB2 is essential for formation of primary cilia in mammalian cells.","Cytoskeleton (Hoboken, N.J.)","2015 Apr","Zhang L, Li W, Ni J, Wu J, Liu J, Zhang Z, Zhang Y, Li H, Shi Y, Teves ME, Song S, Strauss JF 3rd, Zhang Z"
> "Q99LJ7-1","22768142","Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles.","PloS one","2012","Wang J, Teves ME, Shen X, Nagarkatti-Gude DR, Hess RA, Henderson SC, Strauss JF 3rd, Zhang Z"
5882a6472,6477
> "Q8C0X8-1","15289607","The mouse kinome: discovery and comparative genomics of all mouse protein kinases.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G"
> "Q8BZ98-1","28395327","Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.","Biology of reproduction","2017 Jan 1","Zhou W, De Iuliis GN, Turner AP, Reid AT, Anderson AL, McCluskey A, McLaughlin EA, Nixon B"
> "Q8BZ98-1","27251629","Dynamin 1- and 3-Mediated Endocytosis Is Essential for the Development of a Large Central Synapse In Vivo.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2016 Jun 1","Fan F, Funk L, Lou X"
> "Q8BZ98-1","24963135","A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.","eLife","2014 Jun 24","Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P"
> "Q8BZ98-1","24273169","Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting.","The Journal of biological chemistry","2014 Jan 10","Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G, Kremer EJ"
> "Q8BZ98-1","19007685","Dynamin 3 participates in the growth and development of megakaryocytes.","Experimental hematology","2008 Dec","Reems JA, Wang W, Tsubata K, Abdurrahman N, Sundell B, Tijssen MR, van der Schoot E, Di Summa F, Patel-Hett S, Italiano J Jr, Gilligan DM"
5901c6496,6503
< "Q9JMB1-1","12748127","Male mice lacking the Theg (testicular haploid expressed gene) protein undergo normal spermatogenesis and are fertile.","Biology of reproduction","2003 Sep","Mannan AU, Nayernia K, Mueller C, Burfeind P, Adham IM, Engel W"
---
> "Q61220-1","26586761","Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2.","Science (New York, N.Y.)","2015 Nov 20","Jaworski A, Tom I, Tong RK, Gildea HK, Koch AW, Gonzalez LC, Tessier-Lavigne M"
> "Q9DCS1-1","27009467","RORgammat+ cells selectively express redundant cation channels linked to the Golgi apparatus.","Scientific reports","2016 Mar 24","Drujont L, Lemoine A, Moreau A, Bienvenu G, Lancien M, Cens T, Guillot F, Beriou G, Bouchet-Delbos L, Fehling HJ, Chiffoleau E, Nicot AB, Charnet P, Martin JC, Josien R, Cuturi MC, Louvet C"
> "Q52KR2-1","26651291","Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.","Developmental cell","2015 Dec 7","van Erp S, van den Heuvel DMA, Fujita Y, Robinson RA, Hellemons AJCGM, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JAA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ"
> "Q52KR2-1","24023893","Lrig2-deficient mice are protected against PDGFB-induced glioma.","PloS one","2013","Rondahl V, Holmlund C, Karlsson T, Wang B, Faraz M, Henriksson R, Hedman H"
> "Q52KR2-1","24086156","In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.","PLoS genetics","2013","Del Rio T, Nishitani AM, Yu WM, Goodrich LV"
> "P49446-1","25381250","Adaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase in osteoclasts.","The Journal of biological chemistry","2014 Dec 26","Levy-Apter E, Finkelshtein E, Vemulapalli V, Li SS, Bedford MT, Elson A"
> "P49446-1","24694598","Protein tyrosine phosphatases epsilon and alpha perform nonredundant roles in osteoclasts.","Molecular biology of the cell","2014 Jun","Finkelshtein E, Lotinun S, Levy-Apter E, Arman E, den Hertog J, Baron R, Elson A"
> "P49446-1","22722941","Multifaceted modulation of K+ channels by protein-tyrosine phosphatase epsilon tunes neuronal excitability.","The Journal of biological chemistry","2012 Aug 10","Ebner-Bennatan S, Patrich E, Peretz A, Kornilov P, Tiran Z, Elson A, Attali B"
5907c6509
< "Q3UHJ0-1","29774516","Periodic Variation of AAK1 in an Abeta1-42-Induced Mouse Model of Alzheimer's Disease.","Journal of molecular neuroscience : MN","2018 Jun","Fu X, Ke M, Yu W, Wang X, Xiao Q, Gu M, Lu Y"
---
> "O35450-1","15664193","Regulation of p21(WAF1/CIP1) stability by WISp39, a Hsp90 binding TPR protein.","Molecular cell","2005 Jan 21","Jascur T, Brickner H, Salles-Passador I, Barbier V, El Khissiin A, Smith B, Fotedar R, Fotedar A"
5916a6519
> "Q9EPK8-1","30365528","Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium.","PloS one","2018","Mihara H, Uchida K, Koizumi S, Moriyama Y"
5918a6522,6524
> "Q03146-1","29298894","Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.","The Journal of biological chemistry","2018 Feb 23","Sun X, Gupta K, Wu B, Zhang D, Yuan B, Zhang X, Chiang HC, Zhang C, Curiel TJ, Bendeck MP, Hursting S, Hu Y, Li R"
> "Q03146-1","29483153","Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers.","Genes &amp; development","2018 Feb 1","Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z"
> "Q03146-1","27915093","Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis.","Matrix biology : journal of the International Society for Matrix Biology","2017 Jan","Borza CM, Su Y, Tran TL, Yu L, Steyns N, Temple KJ, Skwark MJ, Meiler J, Lindsley CW, Hicks BR, Leitinger B, Zent R, Pozzi A"
5930d6535
< "Q3TTY0-1","23943622","Phospholipase B is activated in response to sterol removal and stimulates acrosome exocytosis in murine sperm.","The Journal of biological chemistry","2013 Sep 27","Asano A, Nelson-Harrington JL, Travis AJ"
5932a6538,6539
> "O35618-1","30012555","Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy.","Genes &amp; development","2018 Aug 1","Van Alstyne M, Simon CM, Sardi SP, Shihabuddin LS, Mentis GZ, Pellizzoni L"
> "O35618-1","24013503","Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.","Genes &amp; development","2013 Sep 1","Bezzi M, Teo SX, Muller J, Mok WC, Sahu SK, Vardy LA, Bonday ZQ, Guccione E"
5939a6547
> "P51125-1","29355642","Calpastatin ablation aggravates the molecular phenotype in cell and animal models of Huntington disease.","Neuropharmacology","2018 May 1","Weber JJ, Kloock SJ, Nagel M, Ortiz-Rios MM, Hofmann J, Riess O, Nguyen HP"
5949a6558,6562
> "Q9EPK2-1","26936825","ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment.","Human molecular genetics","2016 May 15","Wright ZC, Singh RK, Alpino R, Goldberg AF, Sokolov M, Ramamurthy V"
> "Q9EPK2-1","26358772","Long-term rescue of cone photoreceptor degeneration in retinitis pigmentosa 2 (RP2)-knockout mice by gene replacement therapy.","Human molecular genetics","2015 Nov 15","Mookherjee S, Hiriyanna S, Kaneshiro K, Li L, Li Y, Li W, Qian H, Li T, Khanna H, Colosi P, Swaroop A, Wu Z"
> "Q9EPK2-1","26383048","Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice.","Cytoskeleton (Hoboken, N.J.)","2015 Sep","Li L, Rao KN, Zheng-Le Y, Hurd TW, Lillo C, Khanna H"
> "Q9EPK2-1","23745007","Ablation of the X-linked retinitis pigmentosa 2 (Rp2) gene in mice results in opsin mislocalization and photoreceptor degeneration.","Investigative ophthalmology &amp; visual science","2013 Jul 2","Li L, Khan N, Hurd T, Ghosh AK, Cheng C, Molday R, Heckenlively JR, Swaroop A, Khanna H"
> "Q9EPK2-1","20106869","The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium.","Human molecular genetics","2010 Apr 1","Evans RJ, Schwarz N, Nagel-Wolfrum K, Wolfrum U, Hardcastle AJ, Cheetham ME"
5955,5957c6568,6572
< "P58771-1","30567734","Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy.","The Journal of biological chemistry","2019 Feb 22","Rajan S, Jagatheesan G, Petrashevskaya N, Biesiadecki BJ, Warren CM, Riddle T, Liggett S, Wolska BM, Solaro RJ, Wieczorek DF"
< "P39054-1","30291191","Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 23","Buono S, Ross JA, Tasfaout H, Levy Y, Kretz C, Tayefeh L, Matson J, Guo S, Kessler P, Monia BP, Bitoun M, Ochala J, Laporte J, Cowling BS"
< "Q6PDG5-1","27392482","Ablation of BAF170 in Developing and Postnatal Dentate Gyrus Affects Neural Stem Cell Proliferation, Differentiation, and Learning.","Molecular neurobiology","2017 Aug","Tuoc T, Dere E, Radyushkin K, Pham L, Nguyen H, Tonchev AB, Sun G, Ronnenberg A, Shi Y, Staiger JF, Ehrenreich H, Stoykova A"
---
> "Q8BJX2-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
> "Q80XG9-1","23911104","An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells.","Neuron","2013 Aug 21","Siddiqui TJ, Tari PK, Connor SA, Zhang P, Dobie FA, She K, Kawabe H, Wang YT, Brose N, Craig AM"
> "P98083-1","30047409","Hyperglycaemia-induced epigenetic changes drive persistent cardiac dysfunction via the adaptor p66(Shc).","International journal of cardiology","2018 Oct 1","Costantino S, Paneni F, Mitchell K, Mohammed SA, Hussain S, Gkolfos C, Berrino L, Volpe M, Schwarzwald C, Luscher TF, Cosentino F"
> "Q9D6J1-1","26887952","Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.","The Journal of biological chemistry","2016 Apr 1","Sassa T, Hirayama T, Kihara A"
> "Q9D6J1-1","12912983","Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.","The Journal of biological chemistry","2003 Oct 31","Riebeling C, Allegood JC, Wang E, Merrill AH Jr, Futerman AH"
5958a6574
> "P84078-1","12376537","Arf1 dissociates from the clathrin adaptor GGA prior to being inactivated by Arf GTPase-activating proteins.","The Journal of biological chemistry","2002 Dec 6","Jacques KM, Nie Z, Stauffer S, Hirsch DS, Chen LX, Stanley KT, Randazzo PA"
5971a6588
> "P22437-1","8121489","The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1.","Nature","1994 Jan 20","Picot D, Loll PJ, Garavito RM"
5972a6590
> "Q8BHK6-1","28424516","SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.","Nature","2017 Apr 27","Chen J, Zhong MC, Guo H, Davidson D, Mishel S, Lu Y, Rhee I, Perez-Quintero LA, Zhang S, Cruz-Munoz ME, Wu N, Vinh DC, Sinha M, Calderon V, Lowell CA, Danska JS, Veillette A"
5976c6594,6596
< "Q6PE87-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
---
> "Q9CR50-1","15547185","Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.","Journal of the National Cancer Institute","2004 Nov 17","Duan W, Gao L, Druhan LJ, Zhu WG, Morrison C, Otterson GA, Villalona-Calero MA"
> "Q9CR50-1","12654245","Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation.","Cell","2003 Mar 21","Leng RP, Lin Y, Ma W, Wu H, Lemmers B, Chung S, Parant JM, Lozano G, Hakem R, Benchimol S"
> "Q9CR50-1","12200228","Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.","Journal of molecular endocrinology","2002 Aug","Beitel LK, Elhaji YA, Lumbroso R, Wing SS, Panet-Raymond V, Gottlieb B, Pinsky L, Trifiro MA"
5978,5979d6597
< "Q64332-1","30858140","Growth and excitability at synapsin II deficient hippocampal neurons.","Molecular and cellular neurosciences","2019 Apr","Matos H, Quiles R, Andrade R, Bykhovskaia M"
< "Q64332-1","28922833","The Knockout of Synapsin II in Mice Impairs Social Behavior and Functional Connectivity Generating an ASD-like Phenotype.","Cerebral cortex (New York, N.Y. : 1991)","2017 Oct 1","Michetti C, Caruso A, Pagani M, Sabbioni M, Medrihan L, David G, Galbusera A, Morini M, Gozzi A, Benfenati F, Scattoni ML"
5984a6603,6606
> "P97450-1","22038518","Coupling factor 6-induced activation of ecto-F1F(o) complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice.","Diabetologia","2012 Feb","Osanai T, Tanaka M, Magota K, Tomita H, Okumura K"
> "Q64332-1","30858140","Growth and excitability at synapsin II deficient hippocampal neurons.","Molecular and cellular neurosciences","2019 Apr","Matos H, Quiles R, Andrade R, Bykhovskaia M"
> "Q64332-1","28922833","The Knockout of Synapsin II in Mice Impairs Social Behavior and Functional Connectivity Generating an ASD-like Phenotype.","Cerebral cortex (New York, N.Y. : 1991)","2017 Oct 1","Michetti C, Caruso A, Pagani M, Sabbioni M, Medrihan L, David G, Galbusera A, Morini M, Gozzi A, Benfenati F, Scattoni ML"
> "Q3USJ8-1","23437151","FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.","PloS one","2013","Cao H, Yin X, Cao Y, Jin Y, Wang S, Kong Y, Chen Y, Gao J, Heller S, Xu Z"
5992,5994d6613
< "Q6RHR9-1","27707879","MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes.","The Journal of biological chemistry","2016 Nov 18","Ni J, Bao S, Johnson RI, Zhu B, Li J, Vadaparampil J, Smith CM, Campbell KN, Grahammer F, Huber TB, He JC, D'Agati VD, Chan A, Kaufman L"
< "Q6RHR9-1","23523645","Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.","Neuroscience letters","2013 May 10","Qi Y, Ge JY, Wang YN, Liu HY, Li YM, Liu ZH, Cui XL"
< "Q5DTW7-1","29728365","A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.","Genome research","2018 Jun","Fukuda K, Okuda A, Yusa K, Shinkai Y"
6000a6620,6621
> "Q8BMJ8-1","29967281","SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression.","Development (Cambridge, England)","2018 Jul 23","Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z"
> "Q8BMJ8-1","15358670","Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.","Development (Cambridge, England)","2004 Oct","Kawakami Y, Esteban CR, Matsui T, Rodriguez-Leon J, Kato S, Izpisua Belmonte JC"
6003,6004c6624
< "Q71RI9-1","20482848","Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases.","BMC biochemistry","2010 May 19","Han Q, Cai T, Tagle DA, Li J"
< "Q71RI9-1","19029248","Biochemical and structural properties of mouse kynurenine aminotransferase III.","Molecular and cellular biology","2009 Feb","Han Q, Robinson H, Cai T, Tagle DA, Li J"
---
> "Q8R4G0-1","11906208","Laminets: laminin- and netrin-related genes expressed in distinct neuronal subsets.","Molecular and cellular neurosciences","2002 Mar","Yin Y, Miner JH, Sanes JR"
6013a6634,6638
> "Q6KAR6-1","15878854","Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.","The Journal of biological chemistry","2005 Jul 8","Tsuboi T, Ravier MA, Xie H, Ewart MA, Gould GW, Baldwin SA, Rutter GA"
> "Q8BKV0-1","25138526","Structural abnormalities of corpus callosum and cortical axonal tracts accompanied by decreased anxiety-like behavior and lowered sociability in spock3- mutant mice.","Developmental neuroscience","2014","Yamamoto A, Uchiyama K, Nara T, Nishimura N, Hayasaka M, Hanaoka K, Yamamoto T"
> "Q8BKV0-1","23418755","Testican-3: a brain-specific proteoglycan member of the BM-40/SPARC/osteonectin family.","Journal of neurochemistry","2013 May","Hartmann U, Hulsmann H, Seul J, Roll S, Midani H, Breloy I, Hechler D, Muller R, Paulsson M"
> "Q61979-1","23527188","Differential pre-mRNA splicing regulates Nnat isoforms in the hypothalamus after gastric bypass surgery in mice.","PloS one","2013","Scott WR, Gelegen C, Chandarana K, Karra E, Yousseif A, Amouyal C, Choudhury AI, Andreelli F, Withers DJ, Batterham RL"
> "O70165-1","28844702","Ficolin-2 triggers antitumor effect by activating macrophages and CD8(+) T cells.","Clinical immunology (Orlando, Fla.)","2017 Oct","Ding Q, Shen Y, Li D, Yang J, Yu J, Yin Z, Zhang XL"
6015,6017d6639
< "Q00420-1","25200183","A SIRT7-dependent acetylation switch of GABPbeta1 controls mitochondrial function.","Cell metabolism","2014 Nov 4","Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J"
< "Q00420-1","22862946","Targeting tetramer-forming GABPbeta isoforms impairs self-renewal of hematopoietic and leukemic stem cells.","Cell stem cell","2012 Aug 3","Yu S, Jing X, Colgan JD, Zhao DM, Xue HH"
< "Q00420-1","21944889","Naive CD4+ T cells of Peyer's patches produce more IL-6 than those of spleen in response to antigenic stimulation.","Immunology letters","2011 Dec 30","Hashiguchi M, Hachimura S, Ametani A, Sato T, Kojima H, Kumagai Y, Habu S, Kobata T, Kaminogawa S"
6022,6024d6643
< "Q05BQ1-1","24647940","Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2014 Mar 19","Mishra A, Traut MH, Becker L, Klopstock T, Stein V, Klein R"
< "Q05BQ1-1","18268009","The protein dendrite arborization and synapse maturation 1 (Dasm-1) is dispensable for dendrite arborization.","Molecular and cellular biology","2008 Apr","Mishra A, Knerr B, Paixao S, Kramer ER, Klein R"
< "Q05BQ1-1","15755926","Dasm1: a receptor that shapes neuronal dendrites and turns on silent synapses?","Science's STKE : signal transduction knowledge environment","2005 Mar 8","Falls DL"
6026a6646,6649
> "Q80YV2-1","22955283","Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M.","The Journal of biological chemistry","2012 Nov 2","Illert AL, Zech M, Moll C, Albers C, Kreutmair S, Peschel C, Bassermann F, Duyster J"
> "Q80YV2-1","22696294","Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase.","Development (Cambridge, England)","2012 Jul","Illert AL, Kawaguchi H, Antinozzi C, Bassermann F, Quintanilla-Martinez L, von Klitzing C, Hiwatari M, Peschel C, de Rooij DG, Morris SW, Barchi M, Duyster J"
> "Q80YV2-1","22205987","APC/C(Cdh1)-mediated degradation of the F-box protein NIPA is regulated by its association with Skp1.","PloS one","2011","Klitzing Cv, Huss R, Illert AL, Froschl A, Wotzel S, Peschel C, Bassermann F, Duyster J"
> "Q80YV2-1","12748172","Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).","The Journal of biological chemistry","2003 Aug 8","Ouyang T, Bai RY, Bassermann F, von Klitzing C, Klumpen S, Miething C, Morris SW, Peschel C, Duyster J"
6028d6650
< "Q9D2P8-1","26801084","MOBP levels are regulated by Fyn kinase and affect the morphological differentiation of oligodendrocytes.","Journal of cell science","2016 Mar 1","Schafer I, Muller C, Luhmann HJ, White R"
6033a6656,6661
> "Q8CJ53-1","28720386","Cdc42-interacting protein 4 silencing relieves pulmonary fibrosis in STZ-induced diabetic mice via the Wnt/GSK-3beta/beta-catenin pathway.","Experimental cell research","2017 Oct 1","Zhang X, Liu Y, Shao R, Li W"
> "Q8CJ53-1","23881916","Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling.","Blood","2013 Sep 5","Chen Y, Aardema J, Kale S, Whichard ZL, Awomolo A, Blanchard E, Chang B, Myers DR, Ju L, Tran R, Reece D, Christensen H, Boukour S, Debili N, Strom TS, Rawlings D, Vazquez FX, Voth GA, Zhu C, Kahr WH, Lam WA, Corey SJ"
> "Q8CJ53-1","23572514","CIP4 coordinates with phospholipids and actin-associated proteins to localize to the protruding edge and produce actin ribs and veils.","Journal of cell science","2013 Jun 1","Saengsawang W, Taylor KL, Lumbard DC, Mitok K, Price A, Pietila L, Gomez TM, Dent EW"
> "Q8CJ53-1","22920438","Inhibition of Cdc42-interacting protein 4 (CIP4) impairs osteosarcoma tumor progression.","Current cancer drug targets","2013 Jan","Koshkina NV, Yang G, Kleinerman ES"
> "Q8CJ53-1","22361215","The F-BAR protein CIP4 inhibits neurite formation by producing lamellipodial protrusions.","Current biology : CB","2012 Mar 20","Saengsawang W, Mitok K, Viesselmann C, Pietila L, Lumbard DC, Corey SJ, Dent EW"
> "Q8CJ53-1","12054674","Identification and genetic analysis of human and mouse activated Cdc42 interacting protein-4 isoforms.","Biochemical and biophysical research communications","2002 May 24","Wang L, Rudert WA, Grishin A, Dombrosky-Ferlan P, Sullivan K, Deng X, Whitcomb D, Corey S"
6037,6038c6665
< "Q8BP97-1","24859449","Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.","Nature immunology","2014 Jul","Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, Zhang T, Ma F, Wang Q, Wang J, Deng K, Zhuang Y, Wu X, Yu Y, Xu T, Cao X"
< "Q8BP97-1","23610400","Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation.","Proceedings of the National Academy of Sciences of the United States of America","2013 May 7","Liu J, Liu S, Xia M, Xu S, Wang C, Bao Y, Jiang M, Wu Y, Xu T, Cao X"
---
> "Q8K2K6-4","18775314","Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb.","Cell","2008 Sep 5","Pryor PR, Jackson L, Gray SR, Edeling MA, Thompson A, Sanderson CM, Evans PR, Owen DJ, Luzio JP"
6051,6055d6677
< "Q9WVQ1-1","28539383","Glomerulosclerosis Induced by Deficiency of Membrane-Associated Guanylate Kinase Inverted 2 in Kidney Podocytes.","Journal of the American Society of Nephrology : JASN","2017 Sep","Shirata N, Ihara KI, Yamamoto-Nonaka K, Seki T, Makino SI, Oliva Trejo JA, Miyake T, Yamada H, Campbell KN, Nakagawa T, Mori K, Yanagita M, Mundel P, Nishimori K, Asanuma K"
< "Q9WVQ1-1","25993318","Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.","Kidney international","2015 Aug","Lefebvre J, Clarkson M, Massa F, Bradford ST, Charlet A, Buske F, Lacas-Gervais S, Schulz H, Gimpel C, Hata Y, Schaefer F, Schedl A"
< "Q9WVQ1-1","25653350","S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Feb 4","Zhang N, Zhong P, Shin SM, Metallo J, Danielson E, Olsen CM, Liu QS, Lee SH"
< "Q9WVQ1-1","25271328","MAGI-2 scaffold protein is critical for kidney barrier function.","Proceedings of the National Academy of Sciences of the United States of America","2014 Oct 14","Balbas MD, Burgess MR, Murali R, Wongvipat J, Skaggs BJ, Mundel P, Weins A, Sawyers CL"
< "Q9WVQ1-1","14750953","Nectin-dependent localization of synaptic scaffolding molecule (S-SCAM) at the puncta adherentia junctions formed between the mossy fibre terminals and the dendrites of pyramidal cells in the CA3 area of the mouse hippocampus.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2003 Dec","Yamada A, Irie K, Deguchi-Tawarada M, Ohtsuka T, Takai Y"
6059a6682,6683
> "E9Q5C9-1","28493459","Enhanced NOLC1 promotes cell senescence and represses hepatocellular carcinoma cell proliferation by disturbing the organization of nucleolus.","Aging cell","2017 Aug","Yuan F, Zhang Y, Ma L, Cheng Q, Li G, Tong T"
> "E9Q5C9-1","26984997","Three-Dimensional Distribution of UBF and Nopp140 in Relationship to Ribosomal DNA Transcription During Mouse Preimplantation Development.","Biology of reproduction","2016 Apr","Kone MC, Fleurot R, Chebrout M, Debey P, Beaujean N, Bonnet-Garnier A"
6063,6070c6687
< "Q6P069-1","26822088","Sorcin Links Pancreatic beta-Cell Lipotoxicity to ER Ca2+ Stores.","Diabetes","2016 Apr","Marmugi A, Parnis J, Chen X, Carmichael L, Hardy J, Mannan N, Marchetti P, Piemonti L, Bosco D, Johnson P, Shapiro JA, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Thorens B, Valdivia HH, Rutter GA, Leclerc I"
< "Q6P069-1","12824171","Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart.","The Journal of biological chemistry","2003 Sep 5","Farrell EF, Antaramian A, Rueda A, Gomez AM, Valdivia HH"
< "P54310-1","30086728","Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice.","BMC cancer","2018 Aug 7","Xu M, Chang HH, Jung X, Moro A, Chou CEN, King J, Hines OJ, Sinnett-Smith J, Rozengurt E, Eibl G"
< "P54310-1","29232702","Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice.","PLoS genetics","2017 Dec","Xia B, Cai GH, Yang H, Wang SP, Mitchell GA, Wu JW"
< "P54310-1","28851734","Cardiac overexpression of perilipin 2 induces dynamic steatosis: prevention by hormone-sensitive lipase.","American journal of physiology. Endocrinology and metabolism","2017 Dec 1","Ueno M, Suzuki J, Hirose M, Sato S, Imagawa M, Zenimaru Y, Takahashi S, Ikuyama S, Koizumi T, Konoshita T, Kraemer FB, Ishizuka T"
< "Q6GQT0-1","29293958","CDC14A phosphatase is essential for hearing and male fertility in mouse and human.","Human molecular genetics","2018 Mar 1","Imtiaz A, Belyantseva IA, Beirl AJ, Fenollar-Ferrer C, Bashir R, Bukhari I, Bouzid A, Shaukat U, Azaiez H, Booth KT, Kahrizi K, Najmabadi H, Maqsood A, Wilson EA, Fitzgerald TS, Tlili A, Olszewski R, Lund M, Chaudhry T, Rehman AU, Starost MF, Waryah AM, Hoa M, Dong L, Morell RJ, Smith RJH, Riazuddin S, Masmoudi S, Kindt KS, Naz S, Friedman TB"
< "Q6GQT0-1","26283732","Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.","Molecular and cellular biology","2015 Nov","Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, Zhang P"
< "Q6GQT0-1","19270517","The CDC14A phosphatase regulates oocyte maturation in mouse.","Cell cycle (Georgetown, Tex.)","2009 Apr 1","Schindler K, Schultz RM"
---
> "P39053-1","29800726","Cellular fluorescein hyperfluorescence is dynamin-dependent and increased by Tetronic 1107 treatment.","The international journal of biochemistry &amp; cell biology","2018 Aug","Khan TF, Price BL, Morgan PB, Maldonado-Codina C, Dobson CB"
6075d6691
< "Q9CQA0-1","12881717","Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin.","Oncogene","2003 Jul 17","Renou JP, Bierie B, Miyoshi K, Cui Y, Djiane J, Reichenstein M, Shani M, Hennighausen L"
6079c6695
< "Q3UZ01-1","30254136","Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective Rnpc3-deficient mice.","RNA (New York, N.Y.)","2018 Dec","Doggett K, Williams BB, Markmiller S, Geng FS, Coates J, Mieruszynski S, Ernst M, Thomas T, Heath JK"
---
> "Q640M6-1","18667693","GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically regulates the osmoprotective organic osmolyte GPC.","Proceedings of the National Academy of Sciences of the United States of America","2008 Aug 5","Gallazzini M, Ferraris JD, Burg MB"
6082d6697
< "Q5D525-1","16328886","Identification of a new transcript specifically expressed in mouse spermatocytes: mmrp2.","Molecular biology reports","2005 Dec","Gu S, Hu J, Song P, Gong W, Guo M"
6086a6702,6704
> "Q9Z1B3-1","27776973","PLC-beta1 and cell differentiation: An insight into myogenesis and osteogenesis.","Advances in biological regulation","2017 Jan","Ramazzotti G, Faenza I, Fiume R, Billi AM, Manzoli L, Mongiorgi S, Ratti S, McCubrey JA, Suh PG, Cocco L, Follo MY"
> "Q9Z1B3-1","27563828","IPMK and beta-catenin mediate PLC-beta1-dependent signaling in myogenic differentiation.","Oncotarget","2016 Dec 20","Ramazzotti G, Billi AM, Manzoli L, Mazzetti C, Ruggeri A, Erneux C, Kim S, Suh PG, Cocco L, Faenza I"
> "Q9Z1B3-1","27342861","Phospholipase Cbeta1 induces membrane tubulation and is involved in caveolae formation.","Proceedings of the National Academy of Sciences of the United States of America","2016 Jul 12","Inaba T, Kishimoto T, Murate M, Tajima T, Sakai S, Abe M, Makino A, Tomishige N, Ishitsuka R, Ikeda Y, Takeoka S, Kobayashi T"
6091c6709,6711
< "Q60682-1","27831490","Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules.","The Biochemical journal","2017 Jan 1","Romasanta PN, Curto LM, Sarratea MB, Noli Truant S, Antonoglou MB, Fernandez Lynch MJ, Delfino JM, Mariuzza RA, Fernandez MM, Malchiodi EL"
---
> "Q9Z282-1","28049847","Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.","Proceedings of the National Academy of Sciences of the United States of America","2017 Jan 17","Chen P, Zuo H, Xiong H, Kolar MJ, Chu Q, Saghatelian A, Siegwart DJ, Wan Y"
> "Q9Z282-1","12482833","Expression of G2A, a receptor for lysophosphatidylcholine, by macrophages in murine, rabbit, and human atherosclerotic plaques.","Arteriosclerosis, thrombosis, and vascular biology","2002 Dec 1","Rikitake Y, Hirata K, Yamashita T, Iwai K, Kobayashi S, Itoh H, Ozaki M, Ejiri J, Shiomi M, Inoue N, Kawashima S, Yokoyama M"
> "Q0KL02-1","28973398","Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity.","Human molecular genetics","2017 Dec 1","Katrancha SM, Wu Y, Zhu M, Eipper BA, Koleske AJ, Mains RE"
6094,6096c6714,6717
< "Q9D2G5-1","27878645","The Synaptojanins in the murine small and large intestine.","Journal of bioenergetics and biomembranes","2016 Dec","Vazquez-Carretero MD, Carvajal AE, Serrano-Morales JM, Garcia-Miranda P, Ilundain AA, Peral MJ"
< "Q9D2G5-1","24103750","Analysis of an intronic promoter within Synj2.","Biochemical and biophysical research communications","2013 Nov 1","Planchart A"
< "Q9D2G5-1","21423608","A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.","PloS one","2011 Mar 15","Manji SS, Williams LH, Miller KA, Ooms LM, Bahlo M, Mitchell CA, Dahl HH"
---
> "Q6PHZ8-1","23457522","Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.","PloS one","2013","Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST"
> "Q6PHZ8-1","20550899","Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.","Biophysical journal","2010 Jun 16","Liang P, Chen H, Cui Y, Lei L, Wang K"
> "Q6PHZ8-1","20045463","KChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation.","Molecular and cellular neurosciences","2010 Mar","Lin L, Sun W, Wikenheiser AM, Kung F, Hoffman DA"
> "Q6PHZ8-1","15363885","Differential distribution of KChIPs mRNAs in adult mouse brain.","Brain research. Molecular brain research","2004 Sep 28","Xiong H, Kovacs I, Zhang Z"
6099a6721,6731
> "Q6NZQ8-1","30356278","The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner.","PloS one","2018","Bhagwandin C, Ashbeck EL, Whalen M, Bandola-Simon J, Roche PA, Szajman A, Truong SM, Wertheim BC, Klimentidis YC, Ishido S, Renquist BJ, Lybarger L"
> "Q6NZQ8-1","30154416","March1-dependent modulation of donor MHC II on CD103(+) dendritic cells mitigates alloimmunity.","Nature communications","2018 Aug 28","Borges TJ, Murakami N, Machado FD, Murshid A, Lang BJ, Lopes RL, Bellan LM, Uehara M, Antunes KH, Perez-Saez MJ, Birrane G, Vianna P, Goncalves JIB, Zanin RF, Azzi J, Abdi R, Ishido S, Shin JS, Souza APD, Calderwood SK, Riella LV, Bonorino C"
> "Q6NZQ8-1","30001419","MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway.","PloS one","2018","Wilson KR, Liu H, Healey G, Vuong V, Ishido S, Herold MJ, Villadangos JA, Mintern JD"
> "Q6NZQ8-1","29854835","March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation.","Journal of immunology research","2018","Kishta OA, Sabourin A, Simon L, McGovern T, Raymond M, Galbas T, Majdoubi A, Ishido S, Martin JG, Thibodeau J"
> "Q6NZQ8-1","29378848","A major isoform of the E3 ubiquitin ligase March-I in antigen-presenting cells has regulatory sequences within its gene.","The Journal of biological chemistry","2018 Mar 23","Kaul S, Mittal SK, Roche PA"
> "Q6NZQ8-1","21220452","CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation.","The Journal of experimental medicine","2011 Jan 17","Tze LE, Horikawa K, Domaschenz H, Howard DR, Roots CM, Rigby RJ, Way DA, Ohmura-Hoshino M, Ishido S, Andoniou CE, Degli-Esposti MA, Goodnow CC"
> "Q6NZQ8-1","21059907","Ubiquitination regulates MHC class II-peptide complex retention and degradation in dendritic cells.","Proceedings of the National Academy of Sciences of the United States of America","2010 Nov 23","Walseng E, Furuta K, Bosch B, Weih KA, Matsuki Y, Bakke O, Ishido S, Roche PA"
> "Q6NZQ8-1","19917682","Cutting edge: requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells.","Journal of immunology (Baltimore, Md. : 1950)","2009 Dec 1","Ohmura-Hoshino M, Matsuki Y, Mito-Yoshida M, Goto E, Aoki-Kawasumi M, Nakayama M, Ohara O, Ishido S"
> "Q6NZQ8-1","19880452","Discrete domains of MARCH1 mediate its localization, functional interactions, and posttranscriptional control of expression.","Journal of immunology (Baltimore, Md. : 1950)","2009 Nov 15","Jabbour M, Campbell EM, Fares H, Lybarger L"
> "Q6NZQ8-1","17255932","Novel regulation of MHC class II function in B cells.","The EMBO journal","2007 Feb 7","Matsuki Y, Ohmura-Hoshino M, Goto E, Aoki M, Mito-Yoshida M, Uematsu M, Hasegawa T, Koseki H, Ohara O, Nakayama M, Toyooka K, Matsuoka K, Hotta H, Yamamoto A, Ishido S"
> "Q9CYR0-1","23459151","Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres.","Cell research","2013 May","Gu P, Deng W, Lei M, Chang S"
6103a6736,6737
> "Q8C8R3-1","29720258","T-type calcium channels functionally interact with spectrin (alpha/beta) and ankyrin B.","Molecular brain","2018 May 2","Garcia-Caballero A, Zhang FX, Hodgkinson V, Huang J, Chen L, Souza IA, Cain S, Kass J, Alles S, Snutch TP, Zamponi GW"
> "Q8C8R3-1","29133412","Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.","Proceedings of the National Academy of Sciences of the United States of America","2017 Nov 28","Lorenzo DN, Bennett V"
6106,6109c6740,6744
< "P30875-1","30261745","The expression of somatostatin receptor 2 decreases during cyst growth in mice with polycystic kidney disease.","Experimental biology and medicine (Maywood, N.J.)","2018 Sep","Lin C, Happe H, Veraar K, Scharpfenecker M, Peters DJ"
< "P30875-1","29409919","sst2-receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageing.","Progress in neuro-psychopharmacology &amp; biological psychiatry","2018 Aug 30","Prevot TD, Viollet C, Epelbaum J, Dominguez G, Beracochea D, Guillou JL"
< "P30875-1","27986975","Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality.","Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","2017 Jul","Prevot TD, Gastambide F, Viollet C, Henkous N, Martel G, Epelbaum J, Beracochea D, Guillou JL"
< "P30875-1","25683115","Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.","Gastroenterology","2015 Jun","Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F, Delisle MB, Poupot M, Dufresne M, Shimaoka T, Yonehara S, Mathonnet M, Pyronnet S, Bousquet C"
---
> "Q6SJQ7-1","30127493","Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection.","Nature microbiology","2018 Oct","Orchard RC, Wilen CB, Virgin HW"
> "Q6SJQ7-1","30194229","Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.","Proceedings of the National Academy of Sciences of the United States of America","2018 Sep 25","Nelson CA, Wilen CB, Dai YN, Orchard RC, Kim AS, Stegeman RA, Hsieh LL, Smith TJ, Virgin HW, Fremont DH"
> "Q6SJQ7-1","18097021","Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells.","Journal of immunology (Baltimore, Md. : 1950)","2008 Jan 1","Can I, Tahara-Hanaoka S, Hitomi K, Nakano T, Nakahashi-Oda C, Kurita N, Honda S, Shibuya K, Shibuya A"
> "Q6SJQ7-1","17438331","Functional analysis of activating receptor LMIR4 as a counterpart of inhibitory receptor LMIR3.","The Journal of biological chemistry","2007 Jun 22","Izawa K, Kitaura J, Yamanishi Y, Matsuoka T, Oki T, Shibata F, Kumagai H, Nakajima H, Maeda-Yamamoto M, Hauchins JP, Tybulewicz VL, Takai T, Kitamura T"
> "Q6SJQ7-1","16794255","DIgR2, dendritic cell-derived immunoglobulin receptor 2, is one representative of a family of IgSF inhibitory receptors and mediates negative regulation of dendritic cell-initiated antigen-specific T-cell responses.","Blood","2006 Oct 15","Shi L, Luo K, Xia D, Chen T, Chen G, Jiang Y, Li N, Cao X"
6111a6747
> "Q6P9N8-1","22569362","The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.","Nature communications","2012 May 8","Lopez-Domenech G, Serrat R, Mirra S, D'Aniello S, Somorjai I, Abad A, Vitureira N, Garcia-Arumi E, Alonso MT, Rodriguez-Prados M, Burgaya F, Andreu AL, Garcia-Sancho J, Trullas R, Garcia-Fernandez J, Soriano E"
6121a6758,6759
> "Q8R5M8-1","12202822","SynCAM, a synaptic adhesion molecule that drives synapse assembly.","Science (New York, N.Y.)","2002 Aug 30","Biederer T, Sara Y, Mozhayeva M, Atasoy D, Liu X, Kavalali ET, Sudhof TC"
> "Q8R5M8-1","12242005","Identification of the Tslc1 gene, a mouse orthologue of the human tumor suppressor TSLC1 gene.","Gene","2002 Jul 24","Fukami T, Satoh H, Fujita E, Maruyama T, Fukuhara H, Kuramochi M, Takamoto S, Momoi T, Murakami Y"
6123a6762
> "Q3UHJ0-1","29774516","Periodic Variation of AAK1 in an Abeta1-42-Induced Mouse Model of Alzheimer's Disease.","Journal of molecular neuroscience : MN","2018 Jun","Fu X, Ke M, Yu W, Wang X, Xiao Q, Gu M, Lu Y"
6125,6126d6763
< "Q7SIG6-1","28322786","ADP-ribosylation factor-like GTPase 15 enhances insulin-induced AKT phosphorylation in the IR/IRS1/AKT pathway by interacting with ASAP2 and regulating PDPK1 activity.","Biochemical and biophysical research communications","2017 May 13","Zhao J, Wang M, Deng W, Zhong D, Jiang Y, Liao Y, Chen B, Zhang X"
< "Q7SIG6-1","27601625","Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient FcgammaR-mediated phagocytosis.","Journal of leukocyte biology","2017 Feb","Norton RL, Fredericks GJ, Huang Z, Fay JD, Hoffmann FW, Hoffmann PR"
6128a6766
> "Q63870-1","29305555","Impaired lymphoid extracellular matrix impedes antibacterial immunity in epidermolysis bullosa.","Proceedings of the National Academy of Sciences of the United States of America","2018 Jan 23","Nystrom A, Bornert O, Kuhl T, Gretzmeier C, Thriene K, Dengjel J, Pfister-Wartha A, Kiritsi D, Bruckner-Tuderman L"
6131a6770
> "Q6PAR5-1","17189207","Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.","Cell metabolism","2007 Jan","Lodhi IJ, Chiang SH, Chang L, Vollenweider D, Watson RT, Inoue M, Pessin JE, Saltiel AR"
6135a6775,6776
> "Q9JKV2-1","24244486","Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.","PloS one","2013","Chen T, Wu D, Moskaluk CA, Fu Z"
> "Q9JKV2-1","20459822","The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors.","Molecular cancer","2010 May 11","Sturgill TW, Stoddard PB, Cohn SM, Mayo MW"
6141a6783
> "Q8BU91-1","17120765","Physiology of electrogenic SLC26 paralogues.","Novartis Foundation symposium","2006","Romero MF, Chang MH, Plata C, Zandi-Nejad K, Mercado A, Broumand V, Sussman CR, Mount DB"
6151a6794
> "Q9D1T0-1","28193690","LINGO-1 Regulates Oligodendrocyte Differentiation through the Cytoplasmic Gelsolin Signaling Pathway.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2017 Mar 22","Shao Z, Lee X, Huang G, Sheng G, Henderson CE, Louvard D, Sohn J, Pepinsky B, Mi S"
6156,6158c6799,6804
< "O35892-1","11471051","Source and component genes of a 6-200 Mb gene cluster in the house mouse.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Aug","Weichenhan D, Kunze B, Winking H, van Geel M, Osoegawa K, de Jong PJ, Traut W"
< "Q9D385-1","29718757","ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure.","Molecular biology of the cell","2018 Jul 1","Moye AR, Singh R, Kimler VA, Dilan TL, Munezero D, Saravanan T, Goldberg AFX, Ramamurthy V"
< "Q9D385-1","18234692","BART is essential for nuclear retention of STAT3.","International immunology","2008 Mar","Muromoto R, Sekine Y, Imoto S, Ikeda O, Okayama T, Sato N, Matsuda T"
---
> "E9Q3L2-1","29386109","A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis.","Cell reports","2018 Jan 30","Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML"
> "O55102-1","28319092","The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells.","Nature cell biology","2017 Apr","Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, Florens L, Washburn MP, Stadtfeld M, Pinton P, Pagano M"
> "O55102-1","15102850","Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1).","The Journal of biological chemistry","2004 Jul 2","Starcevic M, Dell'Angelica EC"
> "Q8K3G5-1","28412365","Vaccinia-related kinase 3 (VRK3) sets the circadian period and amplitude by affecting the subcellular localization of clock proteins in mammalian cells.","Biochemical and biophysical research communications","2017 May 27","Park N, Song J, Jeong S, Thi Tran T, Ko HW, Kim EY"
> "Q8K3G5-1","27346674","Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation.","Scientific reports","2016 Jun 27","Song H, Kim W, Choi JH, Kim SH, Lee D, Park CH, Kim S, Kim DY, Kim KT"
> "Q8K3G5-1","12782311","Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development.","FEBS letters","2003 Jun 5","Vega FM, Gonzalo P, Gaspar ML, Lazo PA"
6165a6812,6816
> "Q08874-1","30471646","Distribution of mast cells within the mouse heart and its dependency on Mitf.","Molecular immunology","2019 Jan","Ingason AB, Mechmet F, Atacho DAM, Steingrimsson E, Petersen PH"
> "Q08874-1","17438132","Microphthalmia transcription factor isoforms in mast cells and the heart.","Molecular and cellular biology","2007 Jun","Tshori S, Sonnenblick A, Yannay-Cohen N, Kay G, Nechushtan H, Razin E"
> "Q08874-1","17182576","Distinct and shared transcriptomes are regulated by microphthalmia-associated transcription factor isoforms in mast cells.","Journal of immunology (Baltimore, Md. : 1950)","2007 Jan 1","Shahlaee AH, Brandal S, Lee YN, Jie C, Takemoto CM"
> "Q61907-1","28291718","Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria.","Molecular genetics and metabolism","2017 Apr","Jacobs RL, Jiang H, Kennelly JP, Orlicky DJ, Allen RH, Stabler SP, Maclean KN"
> "Q61907-1","28159867","Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase.","Journal of lipid research","2017 Apr","van der Veen JN, Lingrell S, Gao X, Takawale A, Kassiri Z, Vance DE, Jacobs RL"
6167,6170d6817
< "P15806-1","30659202","E47 modulates hepatic glucocorticoid action.","Nature communications","2019 Jan 18","Hemmer MC, Wierer M, Schachtrup K, Downes M, Hubner N, Evans RM, Uhlenhaut NH"
< "P15806-1","29966657","Upregulation of lncRNA VDR/CASC15 induced by facilitates cardiac hypertrophy through modulating miR-432-5p/TLR4 axis.","Biochemical and biophysical research communications","2018 Sep 18","Li C, Zhou G, Feng J, Zhang J, Hou L, Cheng Z"
< "P15806-1","29703840","Transcription factor ID2 prevents E proteins from enforcing a naive T lymphocyte gene program during NK cell development.","Science immunology","2018 Apr 27","Zook EC, Li ZY, Xu Y, de Pooter RF, Verykokakis M, Beaulieu A, Lasorella A, Maienschein-Cline M, Sun JC, Sigvardsson M, Kee BL"
< "P15806-1","29440362","Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8(+) T cells.","The Journal of experimental medicine","2018 Mar 5","Omilusik KD, Nadjsombati MS, Shaw LA, Yu B, Milner JJ, Goldrath AW"
6178d6824
< "P47931-1","20032047","The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice.","Endocrinology","2010 Mar","Kimura F, Sidis Y, Bonomi L, Xia Y, Schneyer A"
6180a6827,6828
> "Q71RI9-1","20482848","Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases.","BMC biochemistry","2010 May 19","Han Q, Cai T, Tagle DA, Li J"
> "Q71RI9-1","19029248","Biochemical and structural properties of mouse kynurenine aminotransferase III.","Molecular and cellular biology","2009 Feb","Han Q, Robinson H, Cai T, Tagle DA, Li J"
6185c6833,6837
< "Q8C5H8-1","23616928","MNADK, a novel liver-enriched mitochondrion-localized NAD kinase.","Biology open","2013 Apr 15","Zhang R"
---
> "Q9JI57-1","29320702","Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.","Cell metabolism","2018 Jan 9","Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S"
> "Q9JI57-1","27295951","RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome.","BMC genomics","2016 Jun 13","Corley SM, Canales CP, Carmona-Mora P, Mendoza-Reinosa V, Beverdam A, Hardeman EC, Wilkins MR, Palmer SJ"
> "Q9JI57-1","27239038","An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter.","Cell reports","2016 Jun 7","Huo Y, Su T, Cai Q, Macara IG"
> "Q8K1E0-1","28000760","Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo.","Scientific reports","2016 Dec 21","Rivera-Monroy J, Musiol L, Unthan-Fechner K, Farkas A, Clancy A, Coy-Vergara J, Weill U, Gockel S, Lin SY, Corey DP, Kohl T, Strobel P, Schuldiner M, Schwappach B, Vilardi F"
> "Q8K1E0-1","18836075","Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.","Proceedings of the National Academy of Sciences of the United States of America","2008 Oct 14","Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S"
6189,6194d6840
< "Q99NF2-1","26977770","A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis.","PLoS genetics","2016 Mar","Spilker C, Nullmeier S, Grochowska KM, Schumacher A, Butnaru I, Macharadze T, Gomes GM, Yuanxiang P, Bayraktar G, Rodenstein C, Geiseler C, Kolodziej A, Lopez-Rojas J, Montag D, Angenstein F, Bar J, D'Hanis W, Roskoden T, Mikhaylova M, Budinger E, Ohl FW, Stork O, Zenclussen AC, Karpova A, Schwegler H, Kreutz MR"
< "Q99NF2-1","25731822","NELF knockout is associated with impaired pubertal development and subfertility.","Molecular and cellular endocrinology","2015 May 15","Quaynor SD, Ko EK, Chorich LP, Sullivan ME, Demir D, Waller JL, Kim HG, Cameron RS, Layman LC"
< "Q99NF2-1","24656816","Negative elongation factor controls energy homeostasis in cardiomyocytes.","Cell reports","2014 Apr 10","Pan H, Qin K, Guo Z, Ma Y, April C, Gao X, Andrews TG, Bokov A, Zhang J, Chen Y, Weintraub ST, Fan JB, Wang D, Hu Y, Aune GJ, Lindsey ML, Li R"
< "Q99NF2-1","24316376","Differential expression of nasal embryonic LHRH factor (NELF) variants in immortalized GnRH neuronal cell lines.","Molecular and cellular endocrinology","2014 Mar 5","Quaynor SD, Goldberg LY, Ko EK, Stanley RK, Demir D, Kim HG, Chorich LP, Cameron RS, Layman LC"
< "Q99NF2-1","24317321","When synaptic proteins meet the genome: transcriptional regulation in cell death and plasticity by the synapto-nuclear messenger Jacob.","Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","2014 Jan","Bera S, Kreutz MR"
< "Q99NF2-1","19608740","Dendritic mRNA targeting of Jacob and N-methyl-d-aspartate-induced nuclear translocation after calpain-mediated proteolysis.","The Journal of biological chemistry","2009 Sep 11","Kindler S, Dieterich DC, Schutt J, Sahin J, Karpova A, Mikhaylova M, Schob C, Gundelfinger ED, Kreienkamp HJ, Kreutz MR"
6204,6207c6850,6854
< "Q0QWG9-1","18509461","Enhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilin.","PloS one","2008 May 28","Takeuchi T, Ohtsuki G, Yoshida T, Fukaya M, Wainai T, Yamashita M, Yamazaki Y, Mori H, Sakimura K, Kawamoto S, Watanabe M, Hirano T, Mishina M"
< "Q0QWG9-1","16168524","Identification and characterization of a novel Delphilin variant with an alternative N-terminus.","Brain research. Molecular brain research","2005 Nov 18","Yamashita T, Miyagi Y, Ono M, Ito H, Watanabe K, Sonoda T, Tsuzuki K, Ozawa S, Aoki I, Okuda K, Mishina M, Kawamoto S"
< "Q0QWG9-1","12628171","Lurcher GRID2-induced death and depolarization can be dissociated in cerebellar Purkinje cells.","Neuron","2003 Mar 6","Selimi F, Lohof AM, Heitz S, Lalouette A, Jarvis CI, Bailly Y, Mariani J"
< "Q0QWG9-1","12372286","A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.","Neuron","2002 Aug 29","Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N"
---
> "Q8BQY8-1","25915840","HUS1 regulates in vivo responses to genotoxic chemotherapies.","Oncogene","2016 Feb 4","Balmus G, Lim PX, Oswald A, Hume KR, Cassano A, Pierre J, Hill A, Huang W, August A, Stokol T, Southard T, Weiss RS"
> "Q8BQY8-1","23468651","Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.","PLoS genetics","2013","Lyndaker AM, Lim PX, Mleczko JM, Diggins CE, Holloway JK, Holmes RJ, Kan R, Schlafer DH, Freire R, Cohen PE, Weiss RS"
> "Q8BQY8-1","22575700","Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.","Human molecular genetics","2012 Aug 1","Balmus G, Zhu M, Mukherjee S, Lyndaker AM, Hume KR, Lee J, Riccio ML, Reeves AP, Sutter NB, Noden DM, Peters RM, Weiss RS"
> "Q8BQY8-1","19918068","Dual inactivation of Hus1 and p53 in the mouse mammary gland results in accumulation of damaged cells and impaired tissue regeneration.","Proceedings of the National Academy of Sciences of the United States of America","2009 Dec 15","Yazinski SA, Westcott PM, Ong K, Pinkas J, Peters RM, Weiss RS"
> "Q8BQY8-1","17220276","Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1.","Molecular and cellular biology","2007 Mar","Levitt PS, Zhu M, Cassano A, Yazinski SA, Liu H, Darfler J, Peters RM, Weiss RS"
6211a6859,6861
> "Q8CHB8-1","28173158","Mutations in the polyglutamylase gene TTLL5, expressed in photoreceptor cells and spermatozoa, are associated with cone-rod degeneration and reduced male fertility.","Human molecular genetics","2016 Oct 15","Bedoni N, Haer-Wigman L, Vaclavik V, Tran VH, Farinelli P, Balzano S, Royer-Bertrand B, El-Asrag ME, Bonny O, Ikonomidis C, Litzistorf Y, Nikopoulos K, Yioti GG, Stefaniotou MI, McKibbin M, Booth AP, Ellingford JM, Black GC, Toomes C, Inglehearn CF, Hoyng CB, Bax N, Klaver CC, Thiadens AA, Murisier F, Schorderet DF, Ali M, Cremers FP, Andreasson S, Munier FL, Rivolta C"
> "Q8CHB8-1","27162334","Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.","Proceedings of the National Academy of Sciences of the United States of America","2016 May 24","Sun X, Park JH, Gumerson J, Wu Z, Swaroop A, Qian H, Roll-Mecak A, Li T"
> "Q8CHB8-1","23558686","Disruption of Ttll5/stamp gene (tubulin tyrosine ligase-like protein 5/SRC-1 and TIF2-associated modulatory protein gene) in male mice causes sperm malformation and infertility.","The Journal of biological chemistry","2013 May 24","Lee GS, He Y, Dougherty EJ, Jimenez-Movilla M, Avella M, Grullon S, Sharlin DS, Guo C, Blackford JA Jr, Awasthi S, Zhang Z, Armstrong SP, London EC, Chen W, Dean J, Simons SS Jr"
6214a6865
> "Q69ZX8-1","17194709","Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.","The Journal of biological chemistry","2007 Mar 16","Barrientos T, Frank D, Kuwahara K, Bezprozvannaya S, Pipes GC, Bassel-Duby R, Richardson JA, Katus HA, Olson EN, Frey N"
6216,6221d6866
< "Q80W99-1","29371110","Intramembranal disulfide cross-linking elucidates the super-quaternary structure of mammalian CatSpers.","Reproductive biology","2018 Mar","Bystroff C"
< "Q80W99-1","20586097","H2O2-induced up-regulation of CatSper3 in mouse brain.","Molecular reproduction and development","2010 Aug","Kim CW, Tak HM, Kim GT, Mun YJ, Jeon BT, Kim HJ, Roh GS, Han J, Kang D"
< "Q80W99-1","18607386","CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model.","Spinal cord","2009 Jan","Rezaian J, Movahedin M, Mowla SJ"
< "Q80W99-1","17344468","Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.","Biology of reproduction","2007 Jul","Jin J, Jin N, Zheng H, Ro S, Tafolla D, Sanders KM, Yan W"
< "Q80W99-1","16107607","Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.","Biology of reproduction","2005 Dec","Jin JL, O'Doherty AM, Wang S, Zheng H, Sanders KM, Yan W"
< "Q80W99-1","12932298","Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis.","Reproductive biology and endocrinology : RB&amp;E","2003 Aug 1","Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D"
6227,6232c6872,6876
< "Q3TJD7-1","27792740","Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice.","PloS one","2016","Urban AE, Quick EO, Miller KP, Krcmery J, Simon HG"
< "Q3TJD7-1","26556890","PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle.","The Biochemical journal","2016 Feb 1","D'Cruz R, Plant PJ, Pablo LA, Lin S, Chackowicz J, Correa J, Bain J, Batt J"
< "Q3TJD7-1","25677945","LIM Mineralization Protein-1 Enhances Bone Morphogenetic Protein-2-Mediated Osteogenesis Through Activation of ERK1/2 MAPK Pathway and Upregulation of Runx2 Transactivity.","Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research","2015 Aug","Pan H, Li X, Wang J, Zhang K, Yang H, Li Z, Zheng Z, Liu H"
< "Q3TJD7-1","25032549","Lim mineralization protein-1 knockout mice have reduced spine trabecular bone density on microcomputed tomography due to decreased bone morphogenetic protein responsiveness.","Neurosurgery","2014 Aug","Gary MF, Viggeswarapu M, Oliver C, Teklemariam M, Sangadala S, Titus L, Boden SD"
< "Q3TJD7-1","21060154","Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.","The Journal of clinical investigation","2010 Dec","Jung CR, Lim JH, Choi Y, Kim DG, Kang KJ, Noh SM, Im DS"
< "Q3TJD7-1","20706776","Immunohistochemical localization of LIM mineralization protein 1 during mouse molar development.","Journal of molecular histology","2010 Oct","Fang P, Wang X, Zhang L, Yuan G, Chen Z, Zhang Q"
---
> "Q8CH02-1","27206982","SUGP1 is a novel regulator of cholesterol metabolism.","Human molecular genetics","2016 Jul 15","Kim MJ, Yu CY, Theusch E, Naidoo D, Stevens K, Kuang YL, Schuetz E, Chaudhry AS, Medina MW"
> "Q3URY2-1","26933123","GEMC1 is a critical regulator of multiciliated cell differentiation.","The EMBO journal","2016 May 2","Terre B, Piergiovanni G, Segura-Bayona S, Gil-Gomez G, Youssef SA, Attolini CS, Wilsch-Brauninger M, Jung C, Rojas AM, Marjanovic M, Knobel PA, Palenzuela L, Lopez-Rovira T, Forrow S, Huttner WB, Valverde MA, de Bruin A, Costanzo V, Stracker TH"
> "Q3URY2-1","26882546","GemC1 controls multiciliogenesis in the airway epithelium.","EMBO reports","2016 Mar","Arbi M, Pefani DE, Kyrousi C, Lalioti ME, Kalogeropoulou A, Papanastasiou AD, Taraviras S, Lygerou Z"
> "Q3URY2-1","26395491","Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche.","Development (Cambridge, England)","2015 Nov 1","Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Gotz M, Lygerou Z, Taraviras S"
> "P61079-1","28469175","Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity.","Nature communications","2017 May 4","Shi Y, Yuan B, Zhu W, Zhang R, Li L, Hao X, Chen S, Hou F"
6236a6881
> "Q62448-1","9049310","A new translational regulator with homology to eukaryotic translation initiation factor 4G.","The EMBO journal","1997 Feb 17","Imataka H, Olsen HS, Sonenberg N"
6241a6887,6890
> "Q9D7I0-1","18677103","Cell cycle regulation by the pro-apoptotic gene Scotin.","Cell cycle (Georgetown, Tex.)","2008 Aug","Gupta RK, Tripathi R, Naidu BJ, Srinivas UK, Shashidhara LS"
> "Q9D7I0-1","18164684","Scotin: A new p63 target gene expressed during epidermal differentiation.","Biochemical and biophysical research communications","2008 Mar 7","Zocchi L, Bourdon JC, Codispoti A, Knight R, Lane DP, Melino G, Terrinoni A"
> "Q9D7I0-1","17889823","The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane.","Archives of biochemistry and biophysics","2007 Nov 1","Draeby I, Woods YL, la Cour JM, Mollerup J, Bourdon JC, Berchtold MW"
> "Q9D7I0-1","12135983","Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane.","The Journal of cell biology","2002 Jul 22","Bourdon JC, Renzing J, Robertson PL, Fernandes KN, Lane DP"
6243,6253d6891
< "Q6SJQ7-1","30127493","Sphingolipid biosynthesis induces a conformational change in the murine norovirus receptor and facilitates viral infection.","Nature microbiology","2018 Oct","Orchard RC, Wilen CB, Virgin HW"
< "Q6SJQ7-1","30194229","Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.","Proceedings of the National Academy of Sciences of the United States of America","2018 Sep 25","Nelson CA, Wilen CB, Dai YN, Orchard RC, Kim AS, Stegeman RA, Hsieh LL, Smith TJ, Virgin HW, Fremont DH"
< "Q6SJQ7-1","18097021","Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells.","Journal of immunology (Baltimore, Md. : 1950)","2008 Jan 1","Can I, Tahara-Hanaoka S, Hitomi K, Nakano T, Nakahashi-Oda C, Kurita N, Honda S, Shibuya K, Shibuya A"
< "Q6SJQ7-1","17438331","Functional analysis of activating receptor LMIR4 as a counterpart of inhibitory receptor LMIR3.","The Journal of biological chemistry","2007 Jun 22","Izawa K, Kitaura J, Yamanishi Y, Matsuoka T, Oki T, Shibata F, Kumagai H, Nakajima H, Maeda-Yamamoto M, Hauchins JP, Tybulewicz VL, Takai T, Kitamura T"
< "Q6SJQ7-1","16794255","DIgR2, dendritic cell-derived immunoglobulin receptor 2, is one representative of a family of IgSF inhibitory receptors and mediates negative regulation of dendritic cell-initiated antigen-specific T-cell responses.","Blood","2006 Oct 15","Shi L, Luo K, Xia D, Chen T, Chen G, Jiang Y, Li N, Cao X"
< "Q9JIY2-1","19535458","Novel roles of hakai in cell proliferation and oncogenesis.","Molecular biology of the cell","2009 Aug","Figueroa A, Kotani H, Toda Y, Mazan-Mamczarz K, Mueller EC, Otto A, Disch L, Norman M, Ramdasi RM, Keshtgar M, Gorospe M, Fujita Y"
< "Q9JIY2-1","12165405","Alteration of E-cadherin and beta-catenin in mouse vestibular epithelia during induction of apoptosis.","Neuroscience letters","2002 Aug 30","Kim TS, Nakagawa T, Endo T, Iguchi F, Murai N, Naito Y, Ito J"
< "O70589-1","28234597","Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice.","Journal of psychiatry &amp; neuroscience : JPN","2017 Jan","Huang TN, Hsueh YP"
< "O70589-1","27036546","X-linked intellectual disability gene CASK regulates postnatal brain growth in a non-cell autonomous manner.","Acta neuropathologica communications","2016 Mar 31","Srivastava S, McMillan R, Willis J, Clark H, Chavan V, Liang C, Zhang H, Hulver M, Mukherjee K"
< "P60762-1","27573846","MRG15 is required for pre-mRNA splicing and spermatogenesis.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 13","Iwamori N, Tominaga K, Sato T, Riehle K, Iwamori T, Ohkawa Y, Coarfa C, Ono E, Matzuk MM"
< "P60762-1","24451372","Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization.","The Journal of biological chemistry","2014 Mar 7","Chen Y, Li J, Dunn S, Xiong S, Chen W, Zhao Y, Chen BB, Mallampalli RK, Zou C"
6257a6896,6898
> "Q3UMR0-1","27066885","A Varp-Binding Protein, RACK1, Regulates Dendrite Outgrowth through Stabilization of Varp Protein in Mouse Melanocytes.","The Journal of investigative dermatology","2016 Aug","Marubashi S, Ohbayashi N, Fukuda M"
> "Q3UMR0-1","19403694","Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes.","Molecular biology of the cell","2009 Jun","Tamura K, Ohbayashi N, Maruta Y, Kanno E, Itoh T, Fukuda M"
> "Q3UMR0-1","16525121","Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics.","Journal of cell science","2006 Mar 15","Zhang X, He X, Fu XY, Chang Z"
6262,6265c6903,6905
< "P13864-1","21163962","Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.","Science (New York, N.Y.)","2011 Feb 25","Song J, Rechkoblit O, Bestor TH, Patel DJ"
< "P13864-1","17371843","Biological functions of DNA methyltransferase 1 require its methyltransferase activity.","Molecular and cellular biology","2007 Jun","Damelin M, Bestor TH"
< "P13864-1","15634679","Stage-by-stage change in DNA methylation status of Dnmt1 locus during mouse early development.","The Journal of biological chemistry","2005 Mar 11","Ko YG, Nishino K, Hattori N, Arai Y, Tanaka S, Shiota K"
< "Q69ZA1-1","24999027","Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.","Experimental neurology","2014 Nov","Chen HR, Lin GT, Huang CK, Fann MJ"
---
> "Q8BWB6-1","19196137","Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells.","Tissue engineering. Part A","2009 Aug","Vaghjiani RJ, Talma S, Murphy CL"
> "Q6V5K9-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
> "Q6P6J4-1","26930515","Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions.","ACS chemical biology","2016 May 20","You C, Wang P, Nay SL, Wang J, Dai X, O'Connor TR, Wang Y"
6271d6910
< "Q61481-4","22012077","Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart.","Basic research in cardiology","2011 Nov","Miller CL, Cai Y, Oikawa M, Thomas T, Dostmann WR, Zaccolo M, Fujiwara K, Yan C"
6272a6912
> "Q9JI38-1","17170069","Pus3p- and Pus1p-dependent pseudouridylation of steroid receptor RNA activator controls a functional switch that regulates nuclear receptor signaling.","Molecular endocrinology (Baltimore, Md.)","2007 Mar","Zhao X, Patton JR, Ghosh SK, Fischel-Ghodsian N, Shen L, Spanjaard RA"
6299a6940,6942
> "Q8BG84-1","28887430","The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis.","Journal of immunology (Baltimore, Md. : 1950)","2017 Oct 15","Kim S, Easterling ER, Price LC, Smith SL, Coligan JE, Park JE, Brand DD, Rosloniec EF, Stuart JM, Kang AH, Myers LK"
> "Q8BG84-1","28336561","Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.","Arteriosclerosis, thrombosis, and vascular biology","2017 May","Smith CW, Thomas SG, Raslan Z, Patel P, Byrne M, Lordkipanidze M, Bem D, Meyaard L, Senis YA, Watson SP, Mazharian A"
> "Q8BG84-1","15100296","The mouse homologue of the leukocyte-associated Ig-like receptor-1 is an inhibitory receptor that recruits Src homology region 2-containing protein tyrosine phosphatase (SHP)-2, but not SHP-1.","Journal of immunology (Baltimore, Md. : 1950)","2004 May 1","Lebbink RJ, de Ruiter T, Verbrugge A, Bril WS, Meyaard L"
6310,6311c6953
< "Q9JL16-1","30232164","The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins.","mSphere","2018 Sep 19","Weiss CM, Trobaugh DW, Sun C, Lucas TM, Diamond MS, Ryman KD, Klimstra WB"
< "Q9JL16-1","19321657","Prevention of embryo loss in non-obese diabetic mice using adoptive ITGA2(+)ISG20(+) natural killer-cell transfer.","Reproduction (Cambridge, England)","2009 Jun","Lin Y, Wang H, Wang W, Zeng S, Zhong Y, Li DJ"
---
> "P17182-1","30242159","Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway.","Nature communications","2018 Sep 21","Dai J, Zhou Q, Chen J, Rexius-Hall ML, Rehman J, Zhou G"
6313a6956
> "Q9D711-1","19372376","Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.","Proceedings of the National Academy of Sciences of the United States of America","2009 May 5","Calvo SE, Pagliarini DJ, Mootha VK"
6315a6959,6961
> "Q8VE65-1","23426901","Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease.","Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research","2013 Jun","Teramachi J, Hiruma Y, Ishizuka S, Ishizuka H, Brown JP, Michou L, Cao H, Galson DL, Subler MA, Zhou H, Dempster DW, Windle JJ, Roodman GD, Kurihara N"
> "Q9D0Z3-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
> "O35457-1","28600126","Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.","Experimental and molecular pathology","2017 Aug","Zimny S, Pohl R, Rein-Fischboeck L, Haberl EM, Krautbauer S, Weiss TS, Buechler C"
6320,6329c6966,6968
< "Q8BLQ9-1","29217450","Cadm2 regulates body weight and energy homeostasis in mice.","Molecular metabolism","2018 Feb","Yan X, Wang Z, Schmidt V, Gauert A, Willnow TE, Heinig M, Poy MN"
< "Q3U108-1","29244194","Arid5a stabilizes OX40 mRNA in murine CD4(+) T cells by recognizing a stem-loop structure in its 3'UTR.","European journal of immunology","2018 Apr","Hanieh H, Masuda K, Metwally H, Chalise JP, Mohamed M, Nyati KK, Standley DM, Li S, Higa M, Zaman MM, Kishimoto T"
< "Q3U108-1","29358370","Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a.","Proceedings of the National Academy of Sciences of the United States of America","2018 Feb 6","Higa M, Oka M, Fujihara Y, Masuda K, Yoneda Y, Kishimoto T"
< "Q3U108-1","28168301","TLR4-induced NF-kappaB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a.","Nucleic acids research","2017 Mar 17","Nyati KK, Masuda K, Zaman MM, Dubey PK, Millrine D, Chalise JP, Higa M, Li S, Standley DM, Saito K, Hanieh H, Kishimoto T"
< "Q3U108-1","28379390","Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury.","International immunology","2017 Feb 1","Dubey PK, Masuda K, Nyati KK, -Uz Zaman MM, Chalise JP, Millrine D, Kai W, Ripley B, Kishimoto T"
< "Q3U108-1","27671645","Arid5a exacerbates IFN-gamma-mediated septic shock by stabilizing T-bet mRNA.","Proceedings of the National Academy of Sciences of the United States of America","2016 Oct 11","Zaman MM, Masuda K, Nyati KK, Dubey PK, Ripley B, Wang K, Chalise JP, Higa M, Hanieh H, Kishimoto T"
< "Q3U108-1","27022145","Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.","The Journal of experimental medicine","2016 Apr 4","Masuda K, Ripley B, Nyati KK, Dubey PK, Zaman MM, Hanieh H, Higa M, Yamashita K, Standley DM, Mashima T, Katahira M, Okamoto T, Matsuura Y, Takeuchi O, Kishimoto T"
< "Q3U108-1","23676272","Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo.","Proceedings of the National Academy of Sciences of the United States of America","2013 Jun 4","Masuda K, Ripley B, Nishimura R, Mino T, Takeuchi O, Shioi G, Kiyonari H, Kishimoto T"
< "Q3U108-1","21346191","Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription.","Molecular biology of the cell","2011 Apr 15","Amano K, Hata K, Muramatsu S, Wakabayashi M, Takigawa Y, Ono K, Nakanishi M, Takashima R, Kogo M, Matsuda A, Nishimura R, Yoneda T"
< "Q8CH25-1","17630952","A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.","The Biochemical journal","2007 Nov 1","Chan CW, Lee YB, Uney J, Flynn A, Tobias JH, Norman M"
---
> "Q9CQN6-1","19656490","Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.","Cell metabolism","2009 Aug","Nilsson R, Schultz IJ, Pierce EL, Soltis KA, Naranuntarat A, Ward DM, Baughman JM, Paradkar PN, Kingsley PD, Culotta VC, Kaplan J, Palis J, Paw BH, Mootha VK"
> "O08917-1","29162604","Suppression of Hepatic FLOT1 (Flotillin-1) by Type 2 Diabetes Mellitus Impairs the Disposal of Remnant Lipoproteins via Syndecan-1.","Arteriosclerosis, thrombosis, and vascular biology","2018 Jan","Chen K, Wu Q, Hu K, Yang C, Wu X, Cheung P, Williams KJ"
> "P49117-1","29291351","The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.","Nature medicine","2018 Feb","Ji YX, Huang Z, Yang X, Wang X, Zhao LP, Wang PX, Zhang XJ, Alves-Bezerra M, Cai L, Zhang P, Lu YX, Bai L, Gao MM, Zhao H, Tian S, Wang Y, Huang ZX, Zhu XY, Zhang Y, Gong J, She ZG, Li F, Cohen DE, Li H"
6332,6335d6970
< "Q8BVZ1-1","29378767","Perilipin 5 Deletion Unmasks an Endoplasmic Reticulum Stress-Fibroblast Growth Factor 21 Axis in Skeletal Muscle.","Diabetes","2018 Apr","Montgomery MK, Mokhtar R, Bayliss J, Parkington HC, Suturin VM, Bruce CR, Watt MJ"
< "Q8BVZ1-1","28919478","Atorvastatin reduces lipid accumulation in the liver by activating protein kinase A-mediated phosphorylation of perilipin 5.","Biochimica et biophysica acta. Molecular and cell biology of lipids","2017 Dec","Gao X, Nan Y, Zhao Y, Yuan Y, Ren B, Sun C, Cao K, Yu M, Feng X, Ye J"
< "Q8BVZ1-1","17234449","LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues.","Biochimica et biophysica acta","2007 Feb","Dalen KT, Dahl T, Holter E, Arntsen B, Londos C, Sztalryd C, Nebb HI"
< "Q8BVZ1-1","16571721","MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha.","The Journal of biological chemistry","2006 May 19","Yamaguchi T, Matsushita S, Motojima K, Hirose F, Osumi T"
6336a6972,6979
> "Q3UTH8-1","30087324","Developmental seizures and mortality result from reducing GABAA receptor alpha2-subunit interaction with collybistin.","Nature communications","2018 Aug 7","Hines RM, Maric HM, Hines DJ, Modgil A, Panzanelli P, Nakamura Y, Nathanson AJ, Cross A, Deeb T, Brandon NJ, Davies P, Fritschy JM, Schindelin H, Moss SJ"
> "Q3UTH8-1","29069083","RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of alpha2 GABAA receptors.","PLoS genetics","2017 Oct","de Groot C, Floriou-Servou A, Tsai YC, Fruh S, Kohler M, Parkin G, Schwerdel C, Bosshard G, Kaila K, Fritschy JM, Tyagarajan SK"
> "Q3UTH8-1","25082542","A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.","The EMBO journal","2014 Sep 17","Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N"
> "Q3UTH8-1","19236916","Increased network excitability and impaired induction of long-term potentiation in the dentate gyrus of collybistin-deficient mice in vivo.","Molecular and cellular neurosciences","2009 May","Jedlicka P, Papadopoulos T, Deller T, Betz H, Schwarzacher SW"
> "Q3UTH8-1","17690689","Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice.","The EMBO journal","2007 Sep 5","Papadopoulos T, Korte M, Eulenburg V, Kubota H, Retiounskaia M, Harvey RJ, Harvey K, O'Sullivan GA, Laube B, Hulsmann S, Geiger JR, Betz H"
> "Q3UTH8-1","16616186","The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor.","Journal of molecular biology","2006 May 26","Xiang S, Kim EY, Connelly JJ, Nassar N, Kirsch J, Winking J, Schwarz G, Schindelin H"
> "P47708-1","28636945","PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury.","Cell reports","2017 Jun 20","Yuan Q, Ren C, Xu W, Petri B, Zhang J, Zhang Y, Kubes P, Wu D, Tang W"
> "O88587-1","28801594","Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice.","Scientific reports","2017 Aug 11","Kanasaki M, Srivastava SP, Yang F, Xu L, Kudoh S, Kitada M, Ueki N, Kim H, Li J, Takeda S, Kanasaki K, Koya D"
6343,6345c6986,6988
< "Q6ZPI0-1","26919559","Jade-1S phosphorylation induced by CK1alpha contributes to cell cycle progression.","Cell cycle (Georgetown, Tex.)","2016","Borgal L, Rinschen MM, Dafinger C, Liebrecht VI, Abken H, Benzing T, Schermer B"
< "Q6ZPI0-1","24097061","A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation.","The EMBO journal","2013 Oct 30","Wan G, Hu X, Liu Y, Han C, Sood AK, Calin GA, Zhang X, Lu X"
< "Q6ZPI0-1","14612400","Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.","Molecular and cellular biology","2003 Dec","Tzouanacou E, Tweedie S, Wilson V"
---
> "P0C5K0-1","15289607","The mouse kinome: discovery and comparative genomics of all mouse protein kinases.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G"
> "Q6RHR9-1","27707879","MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes.","The Journal of biological chemistry","2016 Nov 18","Ni J, Bao S, Johnson RI, Zhu B, Li J, Vadaparampil J, Smith CM, Campbell KN, Grahammer F, Huber TB, He JC, D'Agati VD, Chan A, Kaufman L"
> "Q6RHR9-1","23523645","Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.","Neuroscience letters","2013 May 10","Qi Y, Ge JY, Wang YN, Liu HY, Li YM, Liu ZH, Cui XL"
6351,6353d6993
< "Q9JII5-1","23965306","DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.","Nucleic acids research","2013 Nov","Chen HY, Yu YH, Yen PH"
< "Q9JII5-1","23658607","Differential translation of Dazap1 transcripts during spermatogenesis.","PloS one","2013","Yang CK, Yen P"
< "Q9JII5-1","18669443","DAZAP1, an hnRNP protein, is required for normal growth and spermatogenesis in mice.","RNA (New York, N.Y.)","2008 Sep","Hsu LC, Chen HY, Lin YW, Chu WC, Lin MJ, Yan YT, Yen PH"
6372a7013,7016
> "Q69ZP3-1","25730884","Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis.","Proceedings of the National Academy of Sciences of the United States of America","2015 Mar 10","Shen Y, Ge WP, Li Y, Hirano A, Lee HY, Rohlmann A, Missler M, Tsien RW, Jan LY, Fu YH, Ptacek LJ"
> "Q69ZP3-1","22214848","Dopamine dysregulation in a mouse model of paroxysmal nonkinesigenic dyskinesia.","The Journal of clinical investigation","2012 Feb","Lee HY, Nakayama J, Xu Y, Fan X, Karouani M, Shen Y, Pothos EN, Hess EJ, Fu YH, Edwards RH, Ptacek LJ"
> "Q69ZP3-1","20040360","Silencing MR-1 attenuates inflammatory damage in mice heart induced by AngII.","Biochemical and biophysical research communications","2010 Jan 15","Dai W, Chen H, Jiang J, Kong W, Wang Y"
> "Q69ZP3-1","15496428","The gene for paroxysmal non-kinesigenic dyskinesia encodes an enzyme in a stress response pathway.","Human molecular genetics","2004 Dec 15","Lee HY, Xu Y, Huang Y, Ahn AH, Auburger GW, Pandolfo M, Kwiecinski H, Grimes DA, Lang AE, Nielsen JE, Averyanov Y, Servidei S, Friedman A, Van Bogaert P, Abramowicz MJ, Bruno MK, Sorensen BF, Tang L, Fu YH, Ptacek LJ"
6377,6380d7020
< "Q8BT07-1","29683733","Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Sep","Sinha D, Kalimutho M, Bowles J, Chan AL, Merriner DJ, Bain AL, Simmons JL, Freire R, Lopez JA, Hobbs RM, O'Bryan MK, Khanna KK"
< "Q8BT07-1","26582107","Cep55 regulates spindle organization and cell cycle progression in meiotic oocyte.","Scientific reports","2015 Nov 19","Xu ZY, Ma XS, Qi ST, Wang ZB, Guo L, Schatten H, Sun QY, Sun YP"
< "Q8BT07-1","20176808","TEX14 interacts with CEP55 to block cell abscission.","Molecular and cellular biology","2010 May","Iwamori T, Iwamori N, Ma L, Edson MA, Greenbaum MP, Matzuk MM"
< "Q8BT07-1","20186884","Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes.","Journal of cellular biochemistry","2010 Apr 15","Chang YC, Chen YJ, Wu CH, Wu YC, Yen TC, Ouyang P"
6381a7022,7025
> "Q9Z2X1-1","29773655","FOXP3 interacts with hnRNPF to modulate pre-mRNA alternative splicing.","The Journal of biological chemistry","2018 Jun 29","Du J, Wang Q, Ziegler SF, Zhou B"
> "Q9Z2X1-1","28424160","Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice.","Diabetes","2017 Jul","Lo CS, Shi Y, Chenier I, Ghosh A, Wu CH, Cailhier JF, Ethier J, Lattouf JB, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD"
> "Q9Z2X1-1","28324005","Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice.","Endocrinology","2017 Apr 1","Ghosh A, Abdo S, Zhao S, Wu CH, Shi Y, Lo CS, Chenier I, Alquier T, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD"
> "Q9Z2X1-1","26232095","Overexpression of heterogeneous nuclear ribonucleoprotein F stimulates renal Ace-2 gene expression and prevents TGF-beta1-induced kidney injury in a mouse model of diabetes.","Diabetologia","2015 Oct","Lo CS, Shi Y, Chang SY, Abdo S, Chenier I, Filep JG, Ingelfinger JR, Zhang SL, Chan JS"
6383,6387d7026
< "A2A432-1","30992047","Abnormal level of CUL4B-mediated histone H2A ubiquitination causes disruptive HOX gene expression.","Epigenetics &amp; chromatin","2019 Apr 16","Lin Y, Yu J, Wu J, Wang S, Zhang T"
< "A2A432-1","29106389","CUL4B promotes gastric cancer invasion and metastasis-involvement of upregulation of HER2.","Oncogene","2018 Feb 22","Qi M, Jiao M, Li X, Hu J, Wang L, Zou Y, Zhao M, Zhang R, Liu H, Mi J, Zhang L, Liu L, Gong Y, Han B"
< "A2A432-1","28604389","A cullin 4B-RING E3 ligase complex fine-tunes pancreatic delta cell paracrine interactions.","The Journal of clinical investigation","2017 Jun 30","Li Q, Cui M, Yang F, Li N, Jiang B, Yu Z, Zhang D, Wang Y, Zhu X, Hu H, Li PS, Ning SL, Wang S, Qi H, Song H, He D, Lin A, Zhang J, Liu F, Zhao J, Gao L, Yi F, Xue T, Sun JP, Gong Y, Yu X"
< "A2A432-1","17954973","Cullin4B/E3-ubiquitin ligase negatively regulates beta-catenin.","Journal of biosciences","2007 Sep","Tripathi R, Kota SK, Srinivas UK"
< "A2A432-1","16052071","Cloning and characterization of mouse cullin4B/E3 ubiquitin ligase.","Journal of biosciences","2005 Jun","Tripathi R, Sastry KS, Kota SK, Srinivas UK"
6403a7043,7046
> "Q8C9A2-3","27108838","Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease.","Scientific reports","2016 Apr 25","Nawaz MS, Vik ES, Ronander ME, Solvoll AM, Blicher P, Bjoras M, Alseth I, Dalhus B"
> "F8VPQ2-1","23487765","ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.","Proceedings of the National Academy of Sciences of the United States of America","2013 Mar 19","Wu RC, Jiang M, Beaudet AL, Wu MY"
> "F8VPQ2-1","18728284","Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.","Journal of the National Cancer Institute","2008 Sep 3","Wu MY, Eldin KW, Beaudet AL"
> "F8VPQ2-1","15750587","Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin.","Nature cell biology","2005 Apr","Gonzalo S, Garcia-Cao M, Fraga MF, Schotta G, Peters AH, Cotter SE, Eguia R, Dean DC, Esteller M, Jenuwein T, Blasco MA"
6415a7059
> "Q8BH64-1","14676205","EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.","The Journal of biological chemistry","2004 Mar 12","Guilherme A, Soriano NA, Bose S, Holik J, Bose A, Pomerleau DP, Furcinitti P, Leszyk J, Corvera S, Czech MP"
6417d7060
< "P70429-1","28320969","Ena/VASP proteins regulate activated T-cell trafficking by promoting diapedesis during transendothelial migration.","Proceedings of the National Academy of Sciences of the United States of America","2017 Apr 4","Estin ML, Thompson SB, Traxinger B, Fisher MH, Friedman RS, Jacobelli J"
6421a7065
> "Q7TMB8-1","14508708","Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.","American journal of human genetics","2003 Oct","Chai JH, Locke DP, Greally JM, Knoll JH, Ohta T, Dunai J, Yavor A, Eichler EE, Nicholls RD"
6434a7079
> "Q8BKX1-1","28067313","Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development.","Scientific reports","2017 Jan 9","Chou AM, Sem KP, Lam WJ, Ahmed S, Lim CY"
6437a7083
> "O55239-1","24717514","Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.","Nature","2014 Apr 10","Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB"
6443d7088
< "Q3U213-1","15722415","Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion.","Proceedings of the National Academy of Sciences of the United States of America","2005 Mar 1","Schimenti JC, Reynolds JL, Planchart A"
6451a7097
> "S4R1W5-1","10460589","Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system.","British journal of haematology","1999 Aug","Hotfilder M, Baxendale S, Cross MA, Sablitzky F"
6453c7099
< "Q0P5V9-1","25164149","Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae.","The Biochemical journal","2014 Dec 1","Bartolke R, Heinisch JJ, Wieczorek H, Vitavska O"
---
> "B2RY56-1","30635567","The splicing factor RBM25 controls MYC activity in acute myeloid leukemia.","Nature communications","2019 Jan 11","Ge Y, Schuster MB, Pundhir S, Rapin N, Bagger FO, Sidiropoulos N, Hashem N, Porse BT"
6459a7106,7109
> "Q60936-1","27499294","Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.","Molecular cell","2016 Aug 18","Stefely JA, Licitra F, Laredj L, Reidenbach AG, Kemmerer ZA, Grangeray A, Jaeg-Ehret T, Minogue CE, Ulbrich A, Hutchins PD, Wilkerson EM, Ruan Z, Aydin D, Hebert AS, Guo X, Freiberger EC, Reutenauer L, Jochem A, Chergova M, Johnson IE, Lohman DC, Rush MJP, Kwiecien NW, Singh PK, Schlagowski AI, Floyd BJ, Forsman U, Sindelar PJ, Westphall MS, Pierrel F, Zoll J, Dal Peraro M, Kannan N, Bingman CA, Coon JJ, Isope P, Puccio H, Pagliarini DJ"
> "Q9CQJ7-1","28658604","Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.","Cellular signalling","2017 Oct","Wei R, Li B, Guo J, Li M, Zhu R, Yang X, Gao R"
> "Q9CQJ7-1","28516917","Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.","Nature communications","2017 May 18","Nabti I, Grimes R, Sarna H, Marangos P, Carroll J"
> "Q9CQJ7-1","27524416","mTOR promotes pituitary tumor development through activation of PTTG1.","Oncogene","2017 Feb 16","Chen R, Duan J, Li L, Ma Q, Sun Q, Ma J, Li C, Zhou X, Chen H, Jing Y, Zhao S, Wu X, Zhang H"
6461,6465c7111,7120
< "P35377-1","26294734","Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice.","Haematologica","2015 Dec","Vang D, Paul JA, Nguyen J, Tran H, Vincent L, Yasuda D, Zaveri NT, Gupta K"
< "P35377-1","26290245","Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Aug 19","Ozawa A, Brunori G, Mercatelli D, Wu J, Cippitelli A, Zou B, Xie XS, Williams M, Zaveri NT, Low S, Scherrer G, Kieffer BL, Toll L"
< "Q9WU00-1","30333037","Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.","Molecular neurodegeneration","2018 Oct 17","Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA"
< "Q9WU00-1","30261697","Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues.","International journal of molecular sciences","2018 Sep 27","Yuan J, Wang H, Xiang Y, Hu S, Li S, Wang M, Qiu L, Zhang Y"
< "Q9WU00-1","29625129","A negative feedback loop between microRNA-378 and Nrf1 promotes the development of hepatosteatosis in mice treated with a high fat diet.","Metabolism: clinical and experimental","2018 Aug","Zhang T, Zhao X, Steer CJ, Yan G, Song G"
---
> "P97819-1","27789386","Role of prefrontal cortical calcium-independent phospholipase A2 in antinociceptive effect of the norepinephrine reuptake inhibitor antidepresssant maprotiline.","Neuroscience","2017 Jan 6","Chew WS, Shalini SM, Torta F, Wenk MR, Stohler C, Yeo JF, Herr DR, Ong WY"
> "P97819-1","15024020","Small interfering RNA knockdown of calcium-independent phospholipases A2 beta or gamma inhibits the hormone-induced differentiation of 3T3-L1 preadipocytes.","The Journal of biological chemistry","2004 May 21","Su X, Mancuso DJ, Bickel PE, Jenkins CM, Gross RW"
> "P97819-1","12167650","Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression.","The Journal of biological chemistry","2002 Oct 11","Maggi LB Jr, Moran JM, Scarim AL, Ford DA, Yoon JW, McHowat J, Buller RM, Corbett JA"
> "Q00196-1","26993806","Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2.","Proceedings of the National Academy of Sciences of the United States of America","2016 Apr 5","Hodson DJ, Shaffer AL, Xiao W, Wright GW, Schmitz R, Phelan JD, Yang Y, Webster DE, Rui L, Kohlhammer H, Nakagawa M, Waldmann TA, Staudt LM"
> "Q00196-1","26361887","NF-kappaB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells.","European journal of immunology","2015 Dec","Kilzheimer M, Quandt J, Langhans J, Weihrich P, Wirth T, Brunner C"
> "Q00196-1","26016715","Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis.","Diabetes","2015 Sep","Clarke JD, Dzierlenga AL, Nelson NR, Li H, Werts S, Goedken MJ, Cherrington NJ"
> "Q8BVP5-1","15077195","Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase.","Oncogene","2004 May 27","Mishra SK, Yang Z, Mazumdar A, Talukder AH, Larose L, Kumar R"
> "Q3UHN9-1","29688404","Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation.","Endocrinology","2018 Jun 1","Yin Y, Wang A, Feng L, Wang Y, Zhang H, Zhang I, Bany BM, Ma L"
> "Q3UHN9-1","29330473","Endothelial heparan sulfate deficiency reduces inflammation and fibrosis in murine diabetic nephropathy.","Laboratory investigation; a journal of technical methods and pathology","2018 Apr","Talsma DT, Katta K, Ettema MAB, Kel B, Kusche-Gullberg M, Daha MR, Stegeman CA, van den Born J, Wang L"
> "Q8C0D4-1","18504429","Met-driven invasive growth involves transcriptional regulation of Arhgap12.","Oncogene","2008 Sep 18","Gentile A, D'Alessandro L, Lazzari L, Martinoglio B, Bertotti A, Mira A, Lanzetti L, Comoglio PM, Medico E"
6468a7124
> "P63137-1","30013074","Gabrb2-knockout mice displayed schizophrenia-like and comorbid phenotypes with interneuron-astrocyte-microglia dysregulation.","Translational psychiatry","2018 Jul 17","Yeung RK, Xiang ZH, Tsang SY, Li R, Ho TYC, Li Q, Hui CK, Sham PC, Qiao MQ, Xue H"
6482a7139
> "Q3U4H6-1","21807949","A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome.","Journal of cell science","2011 Aug 15","Keembiyehetty CN, Krzeslak A, Love DC, Hanover JA"
6484,6488c7141,7142
< "Q7JJ13-1","28388437","The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.","Molecular cell","2017 Apr 6","Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA"
< "Q7JJ13-1","28262505","Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.","Molecular cell","2017 Mar 16","Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM"
< "Q7JJ13-1","27865874","Bromodomain-containing protein 2 induces insulin resistance via the mTOR/Akt signaling pathway and an inflammatory response in adipose tissue.","Cellular signalling","2017 Jan","Sun R, Wu Y, Hou W, Sun Z, Wang Y, Wei H, Mo W, Yu M"
< "Q7JJ13-1","26804911","H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs.","Cell reports","2016 Feb 9","Surface LE, Fields PA, Subramanian V, Behmer R, Udeshi N, Peach SE, Carr SA, Jaffe JD, Boyer LA"
< "Q7JJ13-1","9528865","Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice.","Oncogene","1998 Mar 5","Ostrowski J, Florio SK, Denis GV, Suzuki H, Bomsztyk K"
---
> "Q7SIG6-1","28322786","ADP-ribosylation factor-like GTPase 15 enhances insulin-induced AKT phosphorylation in the IR/IRS1/AKT pathway by interacting with ASAP2 and regulating PDPK1 activity.","Biochemical and biophysical research communications","2017 May 13","Zhao J, Wang M, Deng W, Zhong D, Jiang Y, Liao Y, Chen B, Zhang X"
> "Q7SIG6-1","27601625","Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient FcgammaR-mediated phagocytosis.","Journal of leukocyte biology","2017 Feb","Norton RL, Fredericks GJ, Huang Z, Fay JD, Hoffmann FW, Hoffmann PR"
6492a7147
> "Q64008-1","29290584","CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.","Developmental cell","2018 Jan 8","Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R"
6500a7156
> "Q3UQI9-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
6503a7160,7161
> "Q91YM4-1","18255060","Epigenetic modifications and chromatin loop organization explain the different expression profiles of the Tbrg4, WAP and Ramp3 genes.","Experimental cell research","2008 Mar 10","Montazer-Torbati MB, Hue-Beauvais C, Droineau S, Ballester M, Coant N, Aujean E, Petitbarat M, Rijnkels M, Devinoy E"
> "O08665-1","30627913","Semaphorin 3A Negatively Affects Proliferation of Mouse Thymus Epithelial Cells In Vitro.","Bulletin of experimental biology and medicine","2019 Jan","Rutto KV, Ovsyukov KS, Kudryavtsev IV, Kiseleva EP"
6504a7163,7164
> "P63013-1","28366454","Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration.","Stem cell reports","2017 Apr 11","Wilk K, Yeh SA, Mortensen LJ, Ghaffarigarakani S, Lombardo CM, Bassir SH, Aldawood ZA, Lin CP, Intini G"
> "O88346-1","29931346","TNNT1 nemaline myopathy: natural history and therapeutic frontier.","Human molecular genetics","2018 Sep 15","Fox MD, Carson VJ, Feng HZ, Lawlor MW, Gray JT, Brigatti KW, Jin JP, Strauss KA"
6508a7169,7170
> "Q4VBD9-1","14522971","Identification of a novel glial cell line-derived neurotrophic factor-inducible gene required for renal branching morphogenesis.","The Journal of biological chemistry","2003 Dec 12","Fukuda N, Ichihara M, Morinaga T, Kawai K, Hayashi H, Murakumo Y, Matsuo S, Takahashi M"
> "Q8BSI6-1","22927429","Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution.","Proceedings of the National Academy of Sciences of the United States of America","2012 Sep 11","Lee S, Liu B, Lee S, Huang SX, Shen B, Qian SB"
6511a7174
> "Q9JHL1-1","28893864","The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.","EMBO reports","2017 Nov","Vogl C, Butola T, Haag N, Hausrat TJ, Leitner MG, Moutschen M, Lefebvre PP, Speckmann C, Garrett L, Becker L, Fuchs H, Hrabe de Angelis M, Nietzsche S, Kessels MM, Oliver D, Kneussel M, Kilimann MW, Strenzke N"
6517,6521d7179
< "P28659-1","30158053","CELF1 contributes to aberrant alternative splicing patterns in the type 1 diabetic heart.","Biochemical and biophysical research communications","2018 Sep 18","Belanger K, Nutter CA, Li J, Tasnim S, Liu P, Yu P, Kuyumcu-Martinez MN"
< "P28659-1","28874395","CELF1 Mediates Connexin 43 mRNA Degradation in Dilated Cardiomyopathy.","Circulation research","2017 Oct 27","Chang KT, Cheng CF, King PC, Liu SY, Wang GS"
< "P28659-1","28763438","Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regulators.","PLoS biology","2017 Aug","Bai Z, Chai XR, Yoon MJ, Kim HJ, Lo KA, Zhang ZC, Xu D, Siang DTC, Walet ACE, Xu SH, Chia SY, Chen P, Yang H, Ghosh S, Sun L"
< "Q91Z31-1","29045475","Association between RNA-binding protein Ptbp2 and germ cell injury in an experimentally-induced unilateral cryptorchidism murine model.","PloS one","2017","Dou X, Gao J, Gao P, Tang D, Peng D, Mao J, Huang Z, Chen P, Chen H, Ke S, Liang C, Zhang X"
< "Q91Z31-1","10829067","A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing.","Proceedings of the National Academy of Sciences of the United States of America","2000 Jun 6","Polydorides AD, Okano HJ, Yang YY, Stefani G, Darnell RB"
6523a7182,7185
> "Q9CWT3-1","25811986","Osteopetrorickets due to Snx10 deficiency in mice results from both failed osteoclast activity and loss of gastric acid-dependent calcium absorption.","PLoS genetics","2015 Mar","Ye L, Morse LR, Zhang L, Sasaki H, Mills JC, Odgren PR, Sibbel G, Stanley JR, Wong G, Zamarioli A, Battaglino RA"
> "Q9CWT3-1","22174188","SNX10 is required for osteoclast formation and resorption activity.","Journal of cellular biochemistry","2012 May","Zhu CH, Morse LR, Battaglino RA"
> "Q9QZM3-1","26198769","Cardiotrophin-like cytokine factor 1 (CLCF1) and neuropoietin (NP) signalling and their roles in development, adulthood, cancer and degenerative disorders.","Cytokine &amp; growth factor reviews","2015 Oct","Sims NA"
> "Q9JHH2-1","29178985","A complementary role for tetraspanin superfamily member TSSC6 and ADP purinergic P2Y12 receptor in platelets.","Thrombosis research","2018 Jan","Makkawi M, Howells D, Wright MD, Jackson DE"
6529,6535d7190
< "B2RXV4-1","27006955","TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages.","Journal of immunology research","2016","Philip M, Chiu EY, Hajjar AM, Abkowitz JL"
< "B2RXV4-1","26067085","Crucial Role of FLVCR1a in the Maintenance of Intestinal Heme Homeostasis.","Antioxidants &amp; redox signaling","2015 Dec 20","Fiorito V, Forni M, Silengo L, Altruda F, Tolosano E"
< "B2RXV4-1","25582857","Heme exporter FLVCR is required for T cell development and peripheral survival.","Journal of immunology (Baltimore, Md. : 1950)","2015 Feb 15","Philip M, Funkhouser SA, Chiu EY, Phelps SR, Delrow JJ, Cox J, Fink PJ, Abkowitz JL"
< "B2RXV4-1","24486949","Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.","Gastroenterology","2014 May","Vinchi F, Ingoglia G, Chiabrando D, Mercurio S, Turco E, Silengo L, Altruda F, Tolosano E"
< "B2RXV4-1","24021674","FLVCR is necessary for erythroid maturation, may contribute to platelet maturation, but is dispensable for normal hematopoietic stem cell function.","Blood","2013 Oct 17","Byon JC, Chen J, Doty RT, Abkowitz JL"
< "B2RXV4-1","22058337","Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis.","Investigative ophthalmology &amp; visual science","2011 Nov 29","Gnana-Prakasam JP, Reddy SK, Veeranan-Karmegam R, Smith SB, Martin PM, Ganapathy V"
< "B2RXV4-1","18258918","A heme export protein is required for red blood cell differentiation and iron homeostasis.","Science (New York, N.Y.)","2008 Feb 8","Keel SB, Doty RT, Yang Z, Quigley JG, Chen J, Knoblaugh S, Kingsley PD, De Domenico I, Vaughn MB, Kaplan J, Palis J, Abkowitz JL"
6543a7199,7200
> "Q9JMD0-1","27177335","Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes.","Oncotarget","2016 May 24","Dai XX, Xiong H, Zhang M, Sun S, Xiong B"
> "Q9R1M5-1","18804437","A subcortical maternal complex essential for preimplantation mouse embryogenesis.","Developmental cell","2008 Sep","Li L, Baibakov B, Dean J"
6548,6549c7205
< "Q07563-1","28693719","Type XVII collagen coordinates proliferation in the interfollicular epidermis.","eLife","2017 Jul 11","Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuki S, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt FM, Shimizu H"
< "Q9D0Z3-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
---
> "Q61122-1","23935197","Type I IFNs downregulate myeloid cell IFN-gamma receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription.","Journal of immunology (Baltimore, Md. : 1950)","2013 Sep 15","Kearney SJ, Delgado C, Eshleman EM, Hill KK, O'Connor BP, Lenz LL"
6550a7207
> "Q9WTX5-1","27063938","Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.","eLife","2016 Apr 11","Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, Gu Y, Su X, Xia M, Li W, Zhang X, Wang Q, Cao X, Wang J"
6552a7210,7211
> "Q8CAE3-1","28429615","Regulation of vascular large-conductance calcium-activated potassium channels by Nrf2 signalling.","Diabetes &amp; vascular disease research","2017 Jul","Li Y, Wang XL, Sun X, Chai Q, Li J, Thompson B, Shen WK, Lu T, Lee HC"
> "Q8CAE3-1","28487419","Membrane depolarization activates BK channels through ROCK-mediated beta1 subunit surface trafficking to limit vasoconstriction.","Science signaling","2017 May 9","Leo MD, Zhai X, Muralidharan P, Kuruvilla KP, Bulley S, Boop FA, Jaggar JH"
6555a7215,7216
> "Q3TZM9-1","25036826","Cloning and transcriptional expression of mouse mannosyltransferase IV/V cDNA, which is involved in the synthesis of lipid-linked oligosaccharides.","Bioscience, biotechnology, and biochemistry","2014","Nishimura Y, Shimono N, Yoshimoto T, Kamiguchi H, Nishikawa Y"
> "A2APC3-1","27257088","Ttll9-/- mice sperm flagella show shortening of doublet 7, reduction of doublet 5 polyglutamylation and a stall in beating.","Journal of cell science","2016 Jul 15","Konno A, Ikegami K, Konishi Y, Yang HJ, Abe M, Yamazaki M, Sakimura K, Yao I, Shiba K, Inaba K, Setou M"
6561,6563c7222,7224
< "Q2M3X8-1","28803787","Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.","Neuroscience research","2018 Mar","Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI"
< "Q2M3X8-1","28720499","Coronary artery disease associated gene Phactr1 modulates severity of vascular calcification in vitro.","Biochemical and biophysical research communications","2017 Sep 16","Aherrahrou R, Aherrahrou Z, Schunkert H, Erdmann J"
< "Q2M3X8-1","22766235","Different expression patterns of Phactr family members in normal and injured mouse brain.","Neuroscience","2012 Sep 27","Kim JY, Choi SY, Moon Y, Kim HJ, Chin JH, Kim H, Sun W"
---
> "Q8BUL6-1","27859053","B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.","European journal of immunology","2017 Feb","Jayachandran N, Landego I, Hou S, Alessi DR, Marshall AJ"
> "Q8BUL6-1","26242484","TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway.","Neuroscience bulletin","2015 Oct","Chen Y, Mei R, Teng P, Yang A, Hu X, Zhang Z, Qiu M, Zhao X"
> "Q8BUL6-1","22777911","Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.","European journal of immunology","2012 Oct","Landego I, Jayachandran N, Wullschleger S, Zhang TT, Gibson IW, Miller A, Alessi DR, Marshall AJ"
6565a7227,7238
> "Q8BW72-1","29054488","The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice.","Experimental cell research","2017 Dec 1","Zhou J, Wang F, Xu C, Zhou Z, Zhang W"
> "Q8BW72-1","28827393","Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.","Development (Cambridge, England)","2017 Sep 15","Sankar A, Kooistra SM, Gonzalez JM, Ohlsson C, Poutanen M, Helin K"
> "Q8BW72-1","28511912","Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction.","Clinical immunology (Orlando, Fla.)","2017 Jul","Ishiguro K, Watanabe O, Nakamura M, Yamamura T, Matsushita M, Goto H, Hirooka Y"
> "Q8BW72-1","27711046","Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression.","Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","2017 Mar","Pathak SS, Maitra S, Chakravarty S, Kumar A"
> "Q8BTG7-1","28524415","NDRG4, an early detection marker for colorectal cancer, is specifically expressed in enteric neurons.","Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society","2017 Sep","Vaes N, Lentjes MHFM, Gijbels MJ, Rademakers G, Daenen KL, Boesmans W, Wouters KAD, Geuzens A, Qu X, Steinbusch HPJ, Rutten BPF, Baldwin SH, Sharkey KA, Hofstra RMW, van Engeland M, Vanden Berghe P, Melotte V"
> "Q8BTG7-1","27175791","Uterine Expression of NDRG4 Is Induced by Estrogen and Up-Regulated during Embryo Implantation Process in Mice.","PloS one","2016","Yang Q, Gu Y, Zhang X, Wang JM, He YP, Shi Y, Sun ZG, Shi HJ, Wang J"
> "Q8BTG7-1","26780215","N-myc downstream-regulated gene 4, up-regulated by tumor necrosis factor-alpha and nuclear factor kappa B, aggravates cardiac ischemia/reperfusion injury by inhibiting reperfusion injury salvage kinase pathway.","Basic research in cardiology","2016 Mar","Xing Y, Tang B, Zhu C, Li W, Li Z, Zhao J, Gong WD, Wu ZQ, Zhu CC, Zhang YQ"
> "Q8BTG7-1","26801554","Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.","Biochemical and biophysical research communications","2016 Feb 12","Qu X, Li J, Baldwin HS"
> "Q8BTG7-1","17998568","Differential expression patterns of NDRG family proteins in the central nervous system.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2008 Feb","Okuda T, Kokame K, Miyata T"
> "P27512-1","30096208","Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction.","PloS one","2018","Aarts SABM, Reiche ME, den Toom M, Beckers L, Gijbels MJJ, Gerdes N, de Winther MPJ, Lutgens E"
> "P27512-1","29452567","A critical role for both CD40 and VLA5 in angiotensin II-mediated thrombosis and inflammation.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2018 Jun","Senchenkova EY, Russell J, Vital SA, Yildirim A, Orr AW, Granger DN, Gavins FNE"
> "Q9CQA0-1","12881717","Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin.","Oncogene","2003 Jul 17","Renou JP, Bierie B, Miyoshi K, Cui Y, Djiane J, Reichenstein M, Shani M, Hennighausen L"
6569d7241
< "P09838-2","27311013","Molecular Dynamics Simulations and Structural Analysis to Decipher Functional Impact of a Twenty Residue Insert in the Ternary Complex of Mus musculus TdT Isoform.","PloS one","2016","Mutt E, Sowdhamini R"
6571,6572d7242
< "P48381-1","16930429","A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells.","The European journal of neuroscience","2006 Aug","Baas D, Meiniel A, Benadiba C, Bonnafe E, Meiniel O, Reith W, Durand B"
< "P48381-1","15121860","The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification.","Molecular and cellular biology","2004 May","Bonnafe E, Touka M, AitLounis A, Baas D, Barras E, Ucla C, Moreau A, Flamant F, Dubruille R, Couble P, Collignon J, Durand B, Reith W"
6574,6578d7243
< "Q64GA5-1","30161143","Augmented Pla2g4c/Ptgs2/Hpgds axis in bronchial smooth muscle tissues of experimental asthma.","PloS one","2018","Chiba Y, Suto W, Sakai H"
< "Q64GA5-1","22082005","Induction of group IVC phospholipase A2 in allergic asthma: transcriptional regulation by TNFalpha in bronchoepithelial cells.","The Biochemical journal","2012 Feb 15","Bickford JS, Newsom KJ, Herlihy JD, Mueller C, Keeler B, Qiu X, Walters JN, Su N, Wallet SM, Flotte TR, Nick HS"
< "Q64GA5-1","20817734","Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.","The Journal of biological chemistry","2010 Nov 19","Mancuso DJ, Sims HF, Yang K, Kiebish MA, Su X, Jenkins CM, Guan S, Moon SH, Pietka T, Nassir F, Schappe T, Moore K, Han X, Abumrad NA, Gross RW"
< "Q64GA5-1","20452986","cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis.","The Journal of biological chemistry","2010 Jul 9","Vignola MJ, Kashatus DF, Taylor GA, Counter CM, Valdivia RH"
< "Q64GA5-1","17213206","Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.","The Journal of biological chemistry","2007 Mar 23","Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW"
6581a7247
> "Q99MQ4-1","30511172","Periodontal ligament-associated protein-1 gets involved in the development of osseous eruption canal.","Journal of molecular histology","2019 Feb","Yu X, Liu H, Li C, Du Y, Du Y, Zhang S"
6582a7249,7252
> "Q99NE5-1","29891949","Postsynaptic RIM1 modulates synaptic function by facilitating membrane delivery of recycling NMDARs in hippocampal neurons.","Nature communications","2018 Jun 11","Wang J, Lv X, Wu Y, Xu T, Jiao M, Yang R, Li X, Chen M, Yan Y, Chen C, Dong W, Yang W, Zhuo M, Chen T, Luo J, Qiu S"
> "Q99NE5-1","11797010","RIM1alpha is required for presynaptic long-term potentiation.","Nature","2002 Jan 17","Castillo PE, Schoch S, Schmitz F, Sudhof TC, Malenka RC"
> "Q99NE5-1","11797009","RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone.","Nature","2002 Jan 17","Schoch S, Castillo PE, Jo T, Mukherjee K, Geppert M, Wang Y, Schmitz F, Malenka RC, Sudhof TC"
> "P63056-1","16115881","The Optimedin gene is a downstream target of Pax6.","The Journal of biological chemistry","2005 Oct 21","Grinchuk O, Kozmik Z, Wu X, Tomarev S"
6592a7263,7265
> "Q9WUF3-1","23673342","SUMO regulates proteasome-dependent degradation of FLASH/Casp8AP2.","Cell cycle (Georgetown, Tex.)","2013 Jun 15","Vennemann A, Hofmann TG"
> "Q8R104-1","17923681","Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.","Molecular and cellular biology","2007 Dec","Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV Jr, Weissman S, Verdin E, Schwer B"
> "Q8R104-1","15653680","SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes.","The Journal of biological chemistry","2005 Apr 8","Shi T, Wang F, Stieren E, Tong Q"
6603a7277
> "Q9CQD0-1","17660561","Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.","Genetics","2007 Sep","Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH"
6610a7285,7288
> "Q8BVN3-1","18607386","CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model.","Spinal cord","2009 Jan","Rezaian J, Movahedin M, Mowla SJ"
> "Q8BVN3-1","17344468","Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse.","Biology of reproduction","2007 Jul","Jin J, Jin N, Zheng H, Ro S, Tafolla D, Sanders KM, Yan W"
> "Q8BVN3-1","16107607","Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis.","Biology of reproduction","2005 Dec","Jin JL, O'Doherty AM, Wang S, Zheng H, Sanders KM, Yan W"
> "Q8BVN3-1","12932298","Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis.","Reproductive biology and endocrinology : RB&amp;E","2003 Aug 1","Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D"
6614a7293,7295
> "Q6URW6-1","27385019","Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.","PLoS genetics","2016 Jul","Wang JJ, Rau C, Avetisyan R, Ren S, Romay MC, Stolin G, Gong KW, Wang Y, Lusis AJ"
> "Q6URW6-1","28101381","Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice.","Neural plasticity","2016","Fu X, Zhang L, Jin Y, Sun X, Zhang A, Wen Z, Zhou Y, Xia M, Gao J"
> "Q6URW6-1","12598534","Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages.","The Journal of biological chemistry","2003 Apr 25","Buxton DB, Golomb E, Adelstein RS"
6623,6626d7303
< "P97368-1","22987645","Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.","Developmental dynamics : an official publication of the American Association of Anatomists","2012 Nov","Sonnet W, Rezsohazy R, Donnay I"
< "P97368-1","21059917","Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1.","Proceedings of the National Academy of Sciences of the United States of America","2010 Nov 23","Liu J, Wang Y, Birnbaum MJ, Stoffers DA"
< "P97368-1","18223676","Acceleration of chronic myeloproliferation by enforced expression of Meis1 or Meis3 in Icsbp-deficient bone marrow cells.","Oncogene","2008 Jun 19","Hara T, Schwieger M, Kazama R, Okamoto S, Minehata K, Ziegler M, Lohler J, Stocking C"
< "P97368-1","12397630","PBX, MEIS, and IGF-I are potential mediators of retinoic acid-induced proximodistal limb reduction defects.","Teratology","2002 Nov","Qin P, Cimildoro R, Kochhar DM, Soprano KJ, Soprano DR"
6633,6635c7310,7311
< "P39688-1","29353218","Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ss/Fyn pathway.","Redox biology","2018 May","Xin Y, Bai Y, Jiang X, Zhou S, Wang Y, Wintergerst KA, Cui T, Ji H, Tan Y, Cai L"
< "P39688-1","29180007","Tyrosine kinase Fyn regulates iNOS expression in LPS-stimulated astrocytes via modulation of ERK phosphorylation.","Biochemical and biophysical research communications","2018 Jan 1","Ko HM, Lee SH, Bang M, Kim KC, Jeon SJ, Park YM, Han SH, Kim HY, Lee J, Shin CY"
< "Q69Z26-1","27539848","Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.","The Journal of biological chemistry","2016 Oct 7","Nikolaienko RM, Hammel M, Dubreuil V, Zalmai R, Hall DR, Mehzabeen N, Karuppan SJ, Harroch S, Stella SL, Bouyain S"
---
> "Q9JI70-1","30446775","Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation.","Cellular and molecular life sciences : CMLS","2019 Feb","Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL"
> "Q9JM61-1","26822228","THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE-/- mice.","Cardiovascular research","2016 May 1","Haasdijk RA, Den Dekker WK, Cheng C, Tempel D, Szulcek R, Bos FL, Hermkens DM, Chrifi I, Brandt MM, Van Dijk C, Xu YJ, Van De Kamp EH, Blonden LA, Van Bezu J, Sluimer JC, Biessen EA, Van Nieuw Amerongen GP, Duckers HJ"
6643a7320
> "Q924Z4-1","18165233","Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate.","The Journal of biological chemistry","2008 Feb 29","Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH Jr, Futerman AH"
6649a7327
> "Q8BHZ5-1","17043244","Isolation, characterization, and genetic complementation of a cellular mutant resistant to retroviral infection.","Proceedings of the National Academy of Sciences of the United States of America","2006 Oct 24","Agarwal S, Harada J, Schreifels J, Lech P, Nikolai B, Yamaguchi T, Chanda SK, Somia NV"
6658,6659d7335
< "Q9D424-1","27802166","CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa.","Journal of cell science","2016 Dec 1","Young SA, Miyata H, Satouh Y, Aitken RJ, Baker MA, Ikawa M"
< "Q9D424-1","20731842","CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.","Reproductive biology and endocrinology : RB&amp;E","2010 Aug 23","Li YF, He W, Kim YH, Mandal A, Digilio L, Klotz K, Flickinger CJ, Herr JC"
6670a7347,7350
> "Q08048-1","30627913","Semaphorin 3A Negatively Affects Proliferation of Mouse Thymus Epithelial Cells In Vitro.","Bulletin of experimental biology and medicine","2019 Jan","Rutto KV, Ovsyukov KS, Kudryavtsev IV, Kiseleva EP"
> "Q08048-1","30401749","Activation of hepatocyte growth factor/MET signaling initiates oncogenic transformation and enhances tumor aggressiveness in the murine prostate.","The Journal of biological chemistry","2018 Dec 28","Mi J, Hooker E, Balog S, Zeng H, Johnson DT, He Y, Yu EJ, Wu H, Le V, Lee DH, Aldahl J, Gonzalgo ML, Sun Z"
> "Q08048-1","30103949","c-Fos is necessary for HGF-mediated gene regulation and cell migration in Schwann cells.","Biochemical and biophysical research communications","2018 Sep 18","Ko KR, Lee J, Nho B, Kim S"
> "Q08048-1","30066918","Hepatocyte growth factor exerts beneficial effects on mice with type II diabetesinduced chronic renal failure via the NFkappaB pathway.","Molecular medicine reports","2018 Sep","Cheng G, Tang X, Zhang J"
6675a7356,7363
> "Q91ZD6-1","29029019","Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice.","Endocrinology","2017 Dec 1","Wang Y, Pascal LE, Zhong M, Ai J, Wang D, Jing Y, Pilch J, Song Q, Rigatti LH, Graham LE, Nelson JB, Parwani AV, Wang Z"
> "Q91ZD6-1","26935903","EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity.","Nature communications","2016 Mar 3","Li Y, Takahashi Y, Fujii S, Zhou Y, Hong R, Suzuki A, Tsubata T, Hase K, Wang JY"
> "Q91ZD6-1","26328919","Effects of ELL-associated factor 2 on ultraviolet radiation-induced cataract formation in mice.","Molecular medicine reports","2015 Nov","Jiang Y, Fu R, Zhao J, Wu D, Qiao G, Li R, Zhang J"
> "Q91ZD6-1","24260246","Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice.","PloS one","2013","Pascal LE, Ai J, Masoodi KZ, Wang Y, Wang D, Eisermann K, Rigatti LH, O'Malley KJ, Ma HM, Wang X, Dar JA, Parwani AV, Simons BW, Ittman MM, Li L, Davies BJ, Wang Z"
> "Q91ZD6-1","17873910","U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia.","Oncogene","2008 Mar 6","Xiao W, Zhang Q, Habermacher G, Yang X, Zhang AY, Cai X, Hahn J, Liu J, Pins M, Doglio L, Dhir R, Gingrich J, Wang Z"
> "Q91ZD6-1","17892859","Defective FESTA/EAF2-mediated transcriptional activation in S-II-deficient embryonic stem cells.","Biochemical and biophysical research communications","2007 Nov 23","Ito T, Saso K, Arimitsu N, Sekimizu K"
> "Q91ZD6-1","14517999","Expression of murine ELL-associated factor 2 (Eaf2) is developmentally regulated.","Developmental dynamics : an official publication of the American Association of Anatomists","2003 Oct","Li M, Wu X, Zhuang F, Jiang S, Jiang M, Liu YH"
> "G3X9I7-1","18178554","A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.","The Journal of biological chemistry","2008 Mar 7","Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE, Fu M"
6678,6679d7365
< "Q8K202-1","28042089","PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression.","Gene","2017 May 15","Rothblum LI, Rothblum K, Chang E"
< "Q8K202-1","22849406","Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49.","Biochemistry","2012 Aug 21","Penrod Y, Rothblum K, Rothblum LI"
6681a7368,7371
> "Q09143-1","27357826","MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters.","Molecular and cellular biochemistry","2016 Aug","Di Pasqua LG, Berardo C, Rizzo V, Richelmi P, Croce AC, Vairetti M, Ferrigno A"
> "P97497-1","30046278","Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages.","Mediators of inflammation","2018","Yamazaki H, Kushiyama A, Sakoda H, Fujishiro M, Yamamotoya T, Nakatsu Y, Kikuchi T, Kaneko S, Tanaka H, Asano T"
> "Q9Z1J2-1","20103636","Nek4 status differentially alters sensitivity to distinct microtubule poisons.","Cancer research","2010 Feb 1","Doles J, Hemann MT"
> "Q9QYF9-1","17998568","Differential expression patterns of NDRG family proteins in the central nervous system.","The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society","2008 Feb","Okuda T, Kokame K, Miyata T"
6686,6692c7376,7378
< "Q8BPU7-1","30643265","A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis.","Nature immunology","2019 Feb","Arandjelovic S, Perry JSA, Lucas CD, Penberthy KK, Kim TH, Zhou M, Rosen DA, Chuang TY, Bettina AM, Shankman LS, Cohen AH, Gaultier A, Conrads TP, Kim M, Elliott MR, Ravichandran KS"
< "Q8BPU7-1","30219846","Engulfment and Cell Motility Protein 1 Protects Against DSS-induced Colonic Injury in Mice via Rac1 Activation.","Journal of Crohn's &amp; colitis","2019 Jan 1","Zheng XB, Liu HS, Zhang LJ, Liu XH, Zhong XL, Zhou C, Hu T, Wu XR, Hu JC, Lian L, Deng QL, Chen YF, Ke J, He XW, Wu XJ, He XS, Lan P"
< "Q8BPU7-1","29029244","ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection.","The Journal of infectious diseases","2017 Dec 19","Sarkar A, Tindle C, Pranadinata RF, Reed S, Eckmann L, Stappenbeck TS, Ernst PB, Das S"
< "Q8BPU7-1","28219480","De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFbeta-deficient squamous cell carcinoma from transition zones.","eLife","2017 Feb 21","McCauley HA, Chevrier V, Birnbaum D, Guasch G"
< "Q4VBE4-1","26091521","Pikachurin Protein Required for Increase of Cone Electroretinogram B-Wave during Light Adaptation.","PloS one","2015","Nagaya M, Ueno S, Kominami T, Nakanishi A, Koyasu T, Kondo M, Furukawa T, Terasaki H"
< "Q4VBE4-1","21129441","Pikachurin interaction with dystroglycan is diminished by defective O-mannosyl glycosylation in congenital muscular dystrophy models and rescued by LARGE overexpression.","Neuroscience letters","2011 Feb 1","Hu H, Li J, Zhang Z, Yu M"
< "Q4VBE4-1","20682766","Post-translational maturation of dystroglycan is necessary for pikachurin binding and ribbon synaptic localization.","The Journal of biological chemistry","2010 Oct 8","Kanagawa M, Omori Y, Sato S, Kobayashi K, Miyagoe-Suzuki Y, Takeda S, Endo T, Furukawa T, Toda T"
---
> "Q9Z0H0-1","28887320","p53 gain-of-function mutations increase Cdc7-dependent replication initiation.","EMBO reports","2017 Nov","Datta A, Ghatak D, Das S, Banerjee T, Paul A, Butti R, Gorain M, Ghuwalewala S, Roychowdhury A, Alam SK, Das P, Chatterjee R, Dasgupta M, Panda CK, Kundu GC, Roychoudhury S"
> "Q9Z0H0-1","27401717","Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.","Nature communications","2016 Jul 12","Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H"
> "Q9Z0H0-1","24133205","Cell division cycle 7 mediates transforming growth factor-beta-induced smooth muscle maturation through activation of myocardin gene transcription.","The Journal of biological chemistry","2013 Nov 29","Shi N, Chen SY"
6694,6698d7379
< "P40645-1","17433257","Identification and characterization of the human SOX6 promoter.","Biochemical and biophysical research communications","2007 Jun 1","Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI"
< "Q8CGM1-1","28894906","Whole exome sequencing reveals a functional mutation in the GAIN domain of the Bai2 receptor underlying a forward mutagenesis hyperactivity QTL.","Mammalian genome : official journal of the International Mammalian Genome Society","2017 Dec","Speca DJ, Trimmer JS, Peterson AS, Diaz E"
< "Q8CGM1-1","20367554","Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing.","Journal of receptor and signal transduction research","2010 Jun","Okajima D, Kudo G, Yokota H"
< "Q8CGM1-1","16412436","Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor.","FEBS letters","2006 Jan 23","Jeong BC, Kim MY, Lee JH, Kee HJ, Kho DH, Han KE, Qian YR, Kim JK, Kim KK"
< "O55042-1","30503521","Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons.","American journal of human genetics","2018 Dec 6","McClymont SA, Hook PW, Soto AI, Reed X, Law WD, Kerans SJ, Waite EL, Briceno NJ, Thole JF, Heckman MG, Diehl NN, Wszolek ZK, Moore CD, Zhu H, Akiyama JA, Dickel DE, Visel A, Pennacchio LA, Ross OA, Beer MA, McCallion AS"
6699a7381
> "P46737-1","23246432","Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.","Molecular cell","2013 Jan 24","Py BF, Kim MS, Vakifahmetoglu-Norberg H, Yuan J"
6702,6706c7384,7385
< "Q9Z0S6-1","29129401","Deletion of claudin-10 rescues claudin-16-deficient mice from hypomagnesemia and hypercalciuria.","Kidney international","2018 Mar","Breiderhoff T, Himmerkus N, Drewell H, Plain A, Gunzel D, Mutig K, Willnow TE, Muller D, Bleich M"
< "Q9Z0S6-1","28771254","Multiplex epithelium dysfunction due to CLDN10 mutation: the HELIX syndrome.","Genetics in medicine : official journal of the American College of Medical Genetics","2018 Feb","Hadj-Rabia S, Brideau G, Al-Sarraj Y, Maroun RC, Figueres ML, Leclerc-Mercier S, Olinger E, Baron S, Chaussain C, Nochy D, Taha RZ, Knebelmann B, Joshi V, Curmi PA, Kambouris M, Vargas-Poussou R, Bodemer C, Devuyst O, Houillier P, El-Shanti H"
< "Q9Z0S6-1","29145406","The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes.","PloS one","2017","Perez EC, Xander P, Laurindo MFL, Novaes E Brito RR, Vivanco BC, Mortara RA, Mariano M, Lopes JD, Keller AC"
< "Q9Z0S6-1","26340953","Claudin-3, claudin-7, and claudin-10 show different distribution patterns during decidualization and trophoblast invasion in mouse and human.","Histochemistry and cell biology","2015 Dec","Schumann S, Buck VU, Classen-Linke I, Wennemuth G, Grummer R"
< "Q9Z0S6-1","14698084","Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.","Hearing research","2004 Jan","Kitajiri SI, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita S"
---
> "Q99MB2-1","15389597","Chondrocyte protein with a poly-proline region (CHPPR) is a novel mitochondrial protein and promotes mitochondrial fission.","Journal of cellular physiology","2004 Dec","Tonachini L, Monticone M, Puri C, Tacchetti C, Pinton P, Rizzuto R, Cancedda R, Tavella S, Castagnola P"
> "Q63ZW6-1","27377778","COL4A6 is dispensable for autosomal recessive Alport syndrome.","Scientific reports","2016 Jul 5","Murata T, Katayama K, Oohashi T, Jahnukainen T, Yonezawa T, Sado Y, Ishikawa E, Nomura S, Tryggvason K, Ito M"
6707a7387,7388
> "O35474-1","12074641","The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation.","Microvascular research","2002 Jul","Aoka Y, Johnson FL, Penta K, Hirata Ki K, Hidai C, Schatzman R, Varner JA, Quertermous T"
> "O35474-1","11959660","Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3).","American journal of physiology. Heart and circulatory physiology","2002 May","Rezaee M, Penta K, Quertermous T"
6712,6713c7393
< "Q64373-1","29704100","Downregulation of miR-34a promotes endothelial cell growth and suppresses apoptosis in atherosclerosis by regulating Bcl-2.","Heart and vessels","2018 Oct","Su G, Sun G, Liu H, Shu L, Liang Z"
< "Q64373-1","30261081","Infection with flaviviruses requires BCLXL for cell survival.","PLoS pathogens","2018 Sep","Suzuki T, Okamoto T, Katoh H, Sugiyama Y, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Fukuhara T, Ikawa M, Satoh T, Yoshio S, Suzuki R, Saijo M, Huang DCS, Kanto T, Akira S, Matsuura Y"
---
> "G3UWC3-1","24877622","The medial amygdala-medullary PrRP-synthesizing neuron pathway mediates neuroendocrine responses to contextual conditioned fear in male rodents.","Endocrinology","2014 Aug","Yoshida M, Takayanagi Y, Onaka T"
6717a7398,7400
> "P17532-1","30931940","Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.","Nature communications","2019 Apr 1","Chen DQ, Cao G, Chen H, Argyopoulos CP, Yu H, Su W, Chen L, Samuels DC, Zhuang S, Bayliss GP, Zhao S, Yu XY, Vaziri ND, Wang M, Liu D, Mao JR, Ma SX, Zhao J, Zhang Y, Shang YQ, Kang H, Ye F, Cheng XH, Li XR, Zhang L, Meng MX, Guo Y, Zhao YY"
> "P17532-1","30446669","Serotonin signals through a gut-liver axis to regulate hepatic steatosis.","Nature communications","2018 Nov 16","Choi W, Namkung J, Hwang I, Kim H, Lim A, Park HJ, Lee HW, Han KH, Park S, Jeong JS, Bang G, Kim YH, Yadav VK, Karsenty G, Ju YS, Choi C, Suh JM, Park JY, Park S, Kim H"
> "Q8BYR5-1","14530279","A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function.","The Journal of biological chemistry","2003 Dec 26","Speidel D, Varoqueaux F, Enk C, Nojiri M, Grishanin RN, Martin TF, Hofmann K, Brose N, Reim K"
6727,6731d7409
< "Q9Z1T6-2","30295876","PIKfyve accelerates phagosome acidification through activation of TRPML1 while arrests aberrant vacuolation independent of the Ca2+ channel.","Journal of biochemistry","2019 Jan 1","Isobe Y, Nigorikawa K, Tsurumi G, Takemasu S, Takasuga S, Kofuji S, Hazeki K"
< "Q9Z1T6-2","29584722","PIKfyve regulates melanosome biogenesis.","PLoS genetics","2018 Mar","Liggins MC, Flesher JL, Jahid S, Vasudeva P, Eby V, Takasuga S, Sasaki J, Sasaki T, Boissy RE, Ganesan AK"
< "Q9Z1T6-2","28779020","The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.","Journal of immunology (Baltimore, Md. : 1950)","2017 Sep 15","Dayam RM, Sun CX, Choy CH, Mancuso G, Glogauer M, Botelho RJ"
< "Q9Z1T6-2","28533230","Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.","The EMBO journal","2017 Jun 14","Kawasaki T, Ito K, Miyata H, Akira S, Kawai T"
< "Q9Z1T6-2","28396567","Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice.","EMBO molecular medicine","2017 Jun","Tronchere H, Cinato M, Timotin A, Guitou L, Villedieu C, Thibault H, Baetz D, Payrastre B, Valet P, Parini A, Kunduzova O, Boal F"
6733a7412,7418
> "O88561-1","15469937","Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells.","The Journal of biological chemistry","2004 Dec 24","Pei Z, Fraisl P, Berger J, Jia Z, Forss-Petter S, Watkins PA"
> "Q8K1X4-1","29915352","The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.","Nature communications","2018 Jun 18","Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA"
> "Q9DCB1-1","26112184","Expression, regulation and function of Hmgn3 during decidualization in mice.","Molecular and cellular endocrinology","2015 Sep 15","Li DD, Guo CH, Yue L, Duan CC, Yang ZQ, Cao H, Guo B, Yue ZP"
> "Q9DCB1-1","23620591","High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.","The Journal of biological chemistry","2013 Jun 7","Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L, Bohla A, Holter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T, Adamski J, Beckers J, Busch DH, Eickelberg O, Klopstock T, Ollert M, Stoger T, Wolf E, Wurst W, Yildirim AO, Zimmer A, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Garfinkel B, Orly J, Ovcharenko I, Bustin M"
> "Q9DCB1-1","15082770","Chromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1.","Molecular and cellular biology","2004 May","West KL, Castellini MA, Duncan MK, Bustin M"
> "Q9R0Z9-1","29202196","Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.","Journal of the National Cancer Institute","2018 Apr 1","Sanchez-Martin D, Otsuka A, Kabashima K, Ha T, Wang D, Qian X, Lowy DR, Tosato G"
> "Q8BGR5-1","25183871","Simplet/Fam53b is required for Wnt signal transduction by regulating beta-catenin nuclear localization.","Development (Cambridge, England)","2014 Sep","Kizil C, Kuchler B, Yan JJ, Ozhan G, Moro E, Argenton F, Brand M, Weidinger G, Antos CL"
6744a7430
> "Q9CWV1-1","22771120","MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination.","Molecular cell","2012 Aug 24","Lutzmann M, Grey C, Traver S, Ganier O, Maya-Mendoza A, Ranisavljevic N, Bernex F, Nishiyama A, Montel N, Gavois E, Forichon L, de Massy B, Mechali M"
6750,6751c7436,7441
< "Q3UTY6-1","21880733","ADAMTSL6beta protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.","The Journal of biological chemistry","2011 Nov 4","Saito M, Kurokawa M, Oda M, Oshima M, Tsutsui K, Kosaka K, Nakao K, Ogawa M, Manabe R, Suda N, Ganjargal G, Hada Y, Noguchi T, Teranaka T, Sekiguchi K, Yoneda T, Tsuji T"
< "Q3UTY6-1","19940141","ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation.","The Journal of biological chemistry","2010 Feb 12","Tsutsui K, Manabe R, Yamada T, Nakano I, Oguri Y, Keene DR, Sengle G, Sakai LY, Sekiguchi K"
---
> "Q60803-1","30579117","USP25 promotes endotoxin tolerance via suppressing K48-linked ubiquitination and degradation of TRAF3 in Kupffer cells.","Molecular immunology","2019 Feb","Wen J, Bai H, Chen N, Zhang W, Zhu X, Li P, Gong J"
> "Q60803-1","30497068","miR-155-5p is Negatively Associated with Acute Pancreatitis and Inversely Regulates Pancreatic Acinar Cell Progression by Targeting Rela and Traf3.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2018","Liu S, Zou H, Wang Y, Duan X, Chen C, Cheng W, Wang L, Ning N, Tang H, Chen M, Mao X, Peng C, Li H, Jiang Y, Jiang B"
> "Q9D662-1","30065114","Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.","Proceedings of the National Academy of Sciences of the United States of America","2018 Aug 14","Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D"
> "Q80U63-1","30136162","NR4A1 Promotes Cerebral Ischemia Reperfusion Injury by Repressing Mfn2-Mediated Mitophagy and Inactivating the MAPK-ERK-CREB Signaling Pathway.","Neurochemical research","2018 Oct","Zhang Z, Yu J"
> "Q80U63-1","15297672","Structural basis of mitochondrial tethering by mitofusin complexes.","Science (New York, N.Y.)","2004 Aug 6","Koshiba T, Detmer SA, Kaiser JT, Chen H, McCaffery JM, Chan DC"
> "Q91X60-1","29785025","An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling.","Nature medicine","2018 Jun","Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, Kim DI, Emont MP, Zestos AG, Cho JS, Liu J, Kennedy RT, Maillard I, Xu XZS, Wu J"
6754,6756d7443
< "Q9R0C8-1","30450647","The guanine nucleotide exchange factor Vav3 modulates oligodendrocyte precursor differentiation and supports remyelination in white matter lesions.","Glia","2019 Feb","Ulc A, Zeug A, Bauch J, van Leeuwen S, Kuhlmann T, Ffrench-Constant C, Ponimaskin E, Faissner A"
< "Q9R0C8-1","15365099","Differential requirements for Vav proteins in DAP10- and ITAM-mediated NK cell cytotoxicity.","The Journal of experimental medicine","2004 Sep 20","Cella M, Fujikawa K, Tassi I, Kim S, Latinis K, Nishi S, Yokoyama W, Colonna M, Swat W"
< "Q9R0C8-1","15249579","Vav GEFs are required for beta2 integrin-dependent functions of neutrophils.","The Journal of cell biology","2004 Jul 19","Gakidis MA, Cullere X, Olson T, Wilsbacher JL, Zhang B, Moores SL, Ley K, Swat W, Mayadas T, Brugge JS"
6758,6761d7444
< "Q9D2Y4-1","30738250","MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.","Molecular immunology","2019 Mar","Zhang J, Qin D, Yang YJ, Hu GQ, Qin XX, Du CT, Chen W"
< "Q9D2Y4-1","23835476","Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.","Cell research","2013 Aug","Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y, Ma J, Chen W, Zhang Y, Zhou X, Yang Z, Wu SQ, Chen L, Han J"
< "Q9D2Y4-1","23612963","Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling.","The Journal of biological chemistry","2013 Jun 7","Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J"
< "Q9D2Y4-1","22265413","Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.","Cell","2012 Jan 20","Sun L, Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W, Lei X, Wang X"
6765a7449,7451
> "H7BX60-1","30082315","Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1b.","The Journal of biological chemistry","2018 Sep 14","Kratz K, de Lange T"
> "H7BX60-1","17632522","Telomere protection by mammalian Pot1 requires interaction with Tpp1.","Nature structural &amp; molecular biology","2007 Aug","Hockemeyer D, Palm W, Else T, Daniels JP, Takai KK, Ye JZ, Keegan CE, de Lange T, Hammer GD"
> "H7BX60-1","17053789","POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.","The EMBO journal","2006 Nov 1","He H, Multani AS, Cosme-Blanco W, Tahara H, Ma J, Pathak S, Deng Y, Chang S"
6773a7460
> "Q9QZH6-1","29291352","Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma.","Nature medicine","2018 Feb","Wen H, Ma H, Cai Q, Lin S, Lei X, He B, Wu S, Wang Z, Gao Y, Liu W, Liu W, Tao Q, Long Z, Yan M, Li D, Kelley KW, Yang Y, Huang H, Liu Q"
6777,6778d7463
< "Q8R035-1","27029019","Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria.","PLoS genetics","2016 Mar","Feaga HA, Quickel MD, Hankey-Giblin PA, Keiler KC"
< "Q8R035-1","20869366","Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality.","Journal of molecular biology","2010 Nov 26","Handa Y, Hikawa Y, Tochio N, Kogure H, Inoue M, Koshiba S, Guntert P, Inoue Y, Kigawa T, Yokoyama S, Nameki N"
6781a7467,7471
> "Q60819-1","30926899","Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.","Nature communications","2019 Mar 29","Niogret C, Miah SMS, Rota G, Fonta NP, Wang H, Held W, Birchmeier W, Sexl V, Yang W, Vivier E, Ho PC, Brossay L, Guarda G"
> "Q6PCM1-1","29674659","Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch.","Nature communications","2018 Apr 19","Abe Y, Fujiwara Y, Takahashi H, Matsumura Y, Sawada T, Jiang S, Nakaki R, Uchida A, Nagao N, Naito M, Kajimura S, Kimura H, Osborne TF, Aburatani H, Kodama T, Inagaki T, Sakai J"
> "Q6PCM1-1","29526734","Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.","Stem cell reports","2018 Apr 10","Kuroki S, Nakai Y, Maeda R, Okashita N, Akiyoshi M, Yamaguchi Y, Kitano S, Miyachi H, Nakato R, Ichiyanagi K, Shirahige K, Kimura H, Shinkai Y, Tachibana M"
> "Q6PCM1-1","16619273","Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71.","Journal of cellular biochemistry","2006 Sep 1","Knebel J, De Haro L, Janknecht R"
> "O08573-1","29844236","Intestinal Lamina Propria CD4(+) T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.","Infection and immunity","2018 Aug","Yu X, Zhang H, Yu L, Liu M, Zuo Z, Han Q, Zhang J, Tian Z, Zhang C"
6784a7475
> "O54834-1","11668396","Analysis of Mid1, Hccs, Arhgap6, and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf) mutant mice.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Oct","Cormier TA, Prakash SK, Magner DB, Zoghbi HY, Van den Veyver IB"
6786a7478
> "Q8BHB0-1","12796777","An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.","Nature immunology","2003 Jul","Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, Ogura Y, Kawasaki A, Fukase K, Kusumoto S, Valvano MA, Foster SJ, Mak TW, Nunez G, Inohara N"
6808a7501
> "Q9DCH6-1","21980954","AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase.","Traffic (Copenhagen, Denmark)","2012 Jan","Miyata N, Okumoto K, Mukai S, Noguchi M, Fujiki Y"
6811,6816d7503
< "Q8R2Y0-1","27783937","alpha/beta-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility.","Cell reports","2016 Oct 25","Fisette A, Tobin S, Decarie-Spain L, Bouyakdan K, Peyot ML, Madiraju SRM, Prentki M, Fulton S, Alquier T"
< "Q8R2Y0-1","26997277","alpha/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes.","Cell reports","2016 Mar 29","Zhao S, Mugabo Y, Ballentine G, Attane C, Iglesias J, Poursharifi P, Zhang D, Nguyen TA, Erb H, Prentki R, Peyot ML, Joly E, Tobin S, Fulton S, Brown JM, Madiraju SR, Prentki M"
< "Q8R2Y0-1","23806692","Fatty acid amide hydrolase but not monoacyl glycerol lipase controls cell death induced by the endocannabinoid 2-arachidonoyl glycerol in hepatic cell populations.","Biochemical and biophysical research communications","2013 Jul 19","Siegmund SV, Wojtalla A, Schlosser M, Zimmer A, Singer MV"
< "Q8R2Y0-1","21665953","Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons.","The Journal of biological chemistry","2011 Aug 19","Marrs WR, Horne EA, Ortega-Gutierrez S, Cisneros JA, Xu C, Lin YH, Muccioli GG, Lopez-Rodriguez ML, Stella N"
< "Q8R2Y0-1","20657592","The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.","Nature neuroscience","2010 Aug","Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, Xu C, Moller T, Mackie K, Manzoni OJ, Cravatt BF, Stella N"
< "Q8R2Y0-1","18096503","A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.","Chemistry &amp; biology","2007 Dec","Blankman JL, Simon GM, Cravatt BF"
6821c7508,7516
< "Q8BHN3-1","18648322","Temporal neuropathologic and behavioral phenotype of 6neo/6neo Pompe disease mice.","Journal of neuropathology and experimental neurology","2008 Aug","Sidman RL, Taksir T, Fidler J, Zhao M, Dodge JC, Passini MA, Raben N, Thurberg BL, Cheng SH, Shihabuddin LS"
---
> "P09838-2","27311013","Molecular Dynamics Simulations and Structural Analysis to Decipher Functional Impact of a Twenty Residue Insert in the Ternary Complex of Mus musculus TdT Isoform.","PloS one","2016","Mutt E, Sowdhamini R"
> "O54931-1","26432469","A-kinase anchoring protein 2 is required for calcitonin-mediated invasion of cancer cells.","Endocrine-related cancer","2016 Jan","Thakkar A, Aljameeli A, Thomas S, Shah GV"
> "O54931-1","22095752","AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency.","EMBO molecular medicine","2012 Jan","Gold MG, Reichow SL, O'Neill SE, Weisbrod CR, Langeberg LK, Bruce JE, Gonen T, Scott JD"
> "Q8VIK5-1","29577896","Platelet endothelial aggregation receptor-1 (PEAR1) is involved in C2C12 myoblast differentiation.","Experimental cell research","2018 May 15","Cui YF, Yan YQ, Liu D, Pang YS, Wu J, Li SF, Tong HL"
> "Q8VIK5-1","26156496","Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.","Cardiovascular research","2015 Oct 1","Vandenbriele C, Kauskot A, Vandersmissen I, Criel M, Geenens R, Craps S, Luttun A, Janssens S, Hoylaerts MF, Verhamme P"
> "Q8VIK5-1","24743597","The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism.","Molecular biology of the cell","2014 Jun 15","Sullivan CS, Scheib JL, Ma Z, Dang RP, Schafer JM, Hickman FE, Brodsky FM, Ravichandran KS, Carter BD"
> "Q8VIK5-1","22993420","Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2012 Sep 19","Scheib JL, Sullivan CS, Carter BD"
> "Q8VIK5-1","19915564","Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.","Nature neuroscience","2009 Dec","Wu HH, Bellmunt E, Scheib JL, Venegas V, Burkert C, Reichardt LF, Zhou Z, Farinas I, Carter BD"
> "Q8VIK5-1","17226770","Jedi--a novel transmembrane protein expressed in early hematopoietic cells.","Journal of cellular biochemistry","2007 Jun 1","Krivtsov AV, Rozov FN, Zinovyeva MV, Hendrikx PJ, Jiang Y, Visser JW, Belyavsky AV"
6823a7519
> "Q9D1C8-1","25098452","CIIA negatively regulates neuronal cell death induced by oxygen-glucose deprivation and reoxygenation.","Molecular and cellular biochemistry","2014 Dec","Hwang SG, Shim J, Choi EJ"
6828c7524
< "Q6NXH3-1","14612417","The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.","Molecular and cellular biology","2003 Dec","Hsu LC, Liu S, Abedinpour F, Beech RD, Lahti JM, Kidd VJ, Greenspan JA, Yeung CY"
---
> "Q8R3L0-1","18057121","Identification and characterization of a novel family of membrane magnesium transporters, MMgT1 and MMgT2.","American journal of physiology. Cell physiology","2008 Feb","Goytain A, Quamme GA"
6834d7529
< "P51125-1","29355642","Calpastatin ablation aggravates the molecular phenotype in cell and animal models of Huntington disease.","Neuropharmacology","2018 May 1","Weber JJ, Kloock SJ, Nagel M, Ortiz-Rios MM, Hofmann J, Riess O, Nguyen HP"
6838c7533
< "Q9CQ89-1","19645739","Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase.","The FEBS journal","2009 Aug","Liang D, Carvalho S, Bon S, Massoulie J"
---
> "Q8BZQ2-1","17616516","CRISPLD2: a novel NSCLP candidate gene.","Human molecular genetics","2007 Sep 15","Chiquet BT, Lidral AC, Stal S, Mulliken JB, Moreno LM, Arcos-Burgos M, Valencia-Ramirez C, Blanton SH, Hecht JT"
6847,6848d7541
< "Q80V23-1","25032857","Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere maintenance.","Cell death &amp; disease","2014 Jul 17","Gao B, Li K, Wei YY, Zhang J, Li J, Zhang L, Gao JP, Li YY, Huang LG, Lin P, Wei YQ"
< "Q80V23-1","20235149","A novel zinc finger protein Zfp637 behaves as a repressive regulator in myogenic cellular differentiation.","Journal of cellular biochemistry","2010 May 15","Li K, Zhang J, Ren JJ, Wang Q, Yang KY, Xiong ZJ, Mao YQ, Qi YY, Chen XW, Lan F, Wang XJ, Xiao HY, Lin P, Wei YQ"
6851a7545,7546
> "Q7TN75-1","17942406","Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues.","The Journal of biological chemistry","2007 Dec 28","Clark MB, Janicke M, Gottesbuhren U, Kleffmann T, Legge M, Poole ES, Tate WP"
> "Q7TN75-1","15767280","Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshifting.","Nucleic acids research","2005","Manktelow E, Shigemoto K, Brierley I"
6862d7556
< "Q9JJ43-1","30001398","Downregulation of splicing regulator RBFOX1 compromises visual depth perception.","PloS one","2018","Gu L, Bok D, Yu F, Caprioli J, Piri N"
6865d7558
< "P40224-2","30898705","CXCL12 expression in aborted mouse uteri induced by IFN-gamma: Potential anti-inflammatory effect involves in endometrial restoration after abortion in mice.","Gene","2019 Jun 5","Chao HH, Li L, Gao X, Wang C, Yue W"
6867c7560
< "Q6GYP7-1","12200424","Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.","The Journal of biological chemistry","2002 Nov 8","Heng JI, Tan SS"
---
> "Q9WVD5-1","19372376","Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.","Proceedings of the National Academy of Sciences of the United States of America","2009 May 5","Calvo SE, Pagliarini DJ, Mootha VK"
6871a7565,7579
> "Q9JIM1-1","30408123","Changes in aortic reactivity associated with the loss of equilibrative nucleoside transporter 1 (ENT1) in mice.","PloS one","2018","Best KA, Bone DB, Vilas G, Gros R, Hammond JR"
> "Q9JIM1-1","28069792","Targeting ENT1 and adenosine tone for the treatment of Huntington's disease.","Human molecular genetics","2017 Feb 1","Kao YH, Lin MS, Chen CM, Wu YR, Chen HM, Lai HL, Chern Y, Lin CJ"
> "Q9JIM1-1","12062437","PKC regulation of the human equilibrative nucleoside transporter, hENT1.","FEBS letters","2002 Apr 24","Coe I, Zhang Y, McKenzie T, Naydenova Z"
> "Q9R007-3","29126450","The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival.","Journal of translational medicine","2017 Nov 10","Xiong W, Wang H, Lu L, Xi R, Wang F, Gu G, Tao R"
> "Q9R007-3","28824166","CLEC5A is a critical receptor in innate immunity against Listeria infection.","Nature communications","2017 Aug 21","Chen ST, Li FJ, Hsu TY, Liang SM, Yeh YC, Liao WY, Chou TY, Chen NJ, Hsiao M, Yang WB, Hsieh SL"
> "Q9R007-3","27795434","CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo.","Journal of virology","2017 Jan 1","Teng O, Chen ST, Hsu TL, Sia SF, Cole S, Valkenburg SA, Hsu TY, Zheng JT, Tu W, Bruzzone R, Peiris JSM, Hsieh SL, Yen HL"
> "Q9R007-3","27033255","CLEC5A is critical for dengue virus-induced osteoclast activation and bone homeostasis.","Journal of molecular medicine (Berlin, Germany)","2016 Sep","Huang YL, Chen ST, Liu RS, Chen YH, Lin CY, Huang CH, Shu PY, Liao CL, Hsieh SL"
> "Q9R007-3","26927798","Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies.","Journal of immunology (Baltimore, Md. : 1950)","2016 Apr 15","Wortham BW, Eppert BL, Flury JL, Garcia SM, Donica WR, Osterburg A, Joyce-Shaikh B, Cua DJ, Borchers MT"
> "Q9R007-3","19074552","Expression and functional role of MDL-1 (CLEC5A) in mouse myeloid lineage cells.","Journal of leukocyte biology","2009 Mar","Aoki N, Kimura Y, Kimura S, Nagato T, Azumi M, Kobayashi H, Sato K, Tateno M"
> "Q9JJ69-1","15363885","Differential distribution of KChIPs mRNAs in adult mouse brain.","Brain research. Molecular brain research","2004 Sep 28","Xiong H, Kovacs I, Zhang Z"
> "O35732-1","29191940","Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation.","American journal of physiology. Gastrointestinal and liver physiology","2018 Mar 1","Gehrke N, Nagel M, Straub BK, Worns MA, Schuchmann M, Galle PR, Schattenberg JM"
> "O35732-1","29099934","A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1beta Release in Response to a Pathogenic Fungus.","The Journal of infectious diseases","2018 Jan 4","Ketelut-Carneiro N, Ghosh S, Levitz SM, Fitzgerald KA, da Silva JS"
> "O35732-1","28850249","Deletion of c-FLIP from CD11b(hi) Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis.","American journal of respiratory cell and molecular biology","2018 Jan","McCubbrey AL, Barthel L, Mohning MP, Redente EF, Mould KJ, Thomas SM, Leach SM, Danhorn T, Gibbings SL, Jakubzick CV, Henson PM, Janssen WJ"
> "O35732-1","29107687","MiR-150 deficiency ameliorated hepatosteatosis and insulin resistance in nonalcoholic fatty liver disease via targeting CASP8 and FADD-like apoptosis regulator.","Biochemical and biophysical research communications","2017 Dec 16","Zhuge B, Li G"
> "O35732-1","28218919","Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.","Nature medicine","2017 Apr","Wang PX, Ji YX, Zhang XJ, Zhao LP, Yan ZZ, Zhang P, Shen LJ, Yang X, Fang J, Tian S, Zhu XY, Gong J, Zhang X, Wei QF, Wang Y, Li J, Wan L, Xie Q, She ZG, Wang Z, Huang Z, Li H"
6877,6880d7584
< "Q920M5-1","24523531","Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2014 Feb 12","Chen Y, Ip FC, Shi L, Zhang Z, Tang H, Ng YP, Ye WC, Fu AK, Ip NY"
< "O70263-1","29121065","Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.","PloS one","2017","Lenihan JA, Saha O, Young PW"
< "O70263-1","19295125","The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells.","Journal of cell science","2009 Apr 1","Takahashi S, Iwamoto N, Sasaki H, Ohashi M, Oda Y, Tsukita S, Furuse M"
< "O70263-1","12468544","The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).","The Journal of biological chemistry","2003 Feb 28","Sollerbrant K, Raschperger E, Mirza M, Engstrom U, Philipson L, Ljungdahl PO, Pettersson RF"
6882,6883d7585
< "Q9QYB5-1","22706708","gamma-Adducin promotes process outgrowth and secretory protein exit from the Golgi apparatus.","Journal of molecular neuroscience : MN","2013 Jan","Lou H, Park JJ, Phillips A, Loh YP"
< "Q9QYB5-1","19900187","beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits.","Genes, brain, and behavior","2010 Feb","Porro F, Rosato-Siri M, Leone E, Costessi L, Iaconcig A, Tongiorgi E, Muro AF"
6887a7590,7591
> "Q8K1B8-1","30783087","Kindlin-2 links mechano-environment to proline synthesis and tumor growth.","Nature communications","2019 Feb 19","Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y, Wu C"
> "Q8K1B8-1","29656482","Kindlin-3 negatively regulates the release of neutrophil extracellular traps.","Journal of leukocyte biology","2018 Sep","Xu Z, Ni B, Cao Z, Zielonka J, Gao J, Chen F, Kalyanaraman B, White GC, Ma YQ"
6891a7596
> "P27573-1","22457349","L-MPZ, a novel isoform of myelin P0, is produced by stop codon readthrough.","The Journal of biological chemistry","2012 May 18","Yamaguchi Y, Hayashi A, Campagnoni CW, Kimura A, Inuzuka T, Baba H"
6898a7604,7606
> "Q5VCS6-1","29317670","TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice.","Nature communications","2018 Jan 9","Ding D, Liu J, Midic U, Wu Y, Dong K, Melnick A, Latham KE, Chen C"
> "Q5VCS6-1","21383078","TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.","The Journal of cell biology","2011 Mar 7","Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M"
> "Q5VCS6-1","15465492","Expression of the tudor-related gene Tdrd5 during development of the male germline in mice.","Gene expression patterns : GEP","2004 Oct","Smith JM, Bowles J, Wilson M, Teasdale RD, Koopman P"
6899a7608,7610
> "Q8BFW7-1","23447672","A complex containing LPP and alpha-actinin mediates TGFbeta-induced migration and invasion of ErbB2-expressing breast cancer cells.","Journal of cell science","2013 May 1","Ngan E, Northey JJ, Brown CM, Ursini-Siegel J, Siegel PM"
> "Q8BFW7-1","22886954","TGF-beta1-induced LPP expression dependant on Rho kinase during differentiation and migration of bone marrow-derived smooth muscle progenitor cells.","Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban","2012 Aug","Qu Z, Yu J, Ruan Q"
> "Q8BFW7-1","12441356","The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein.","The Journal of biological chemistry","2003 Jan 24","Petit MM, Meulemans SM, Van de Ven WJ"
6904,6906c7615
< "Q80XB4-1","21998026","The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.","Genesis (New York, N.Y. : 2000)","2012 Apr","Krebs LT, Bradley CK, Norton CR, Xu J, Oram KF, Starling C, Deftos ML, Bevan MJ, Gridley T"
< "Q80XB4-1","21276443","Cardiac-specific NRAP overexpression causes right ventricular dysfunction in mice.","Experimental cell research","2011 May 1","Lu S, Crawford GL, Dore J, Anderson SA, Despres D, Horowits R"
< "Q80XB4-1","12789664","Genomic organization, alternative splicing, and expression of human and mouse N-RAP, a nebulin-related LIM protein of striated muscle.","Cell motility and the cytoskeleton","2003 Jul","Mohiddin SA, Lu S, Cardoso JP, Carroll S, Jha S, Horowits R, Fananapazir L"
---
> "P97765-1","21642474","Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor alpha function in breast cancer via the Wnt pathway.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2011 Sep","Lim SK, Orhant-Prioux M, Toy W, Tan KY, Lim YP"
6909,6917d7617
< "P52479-1","30898698","Long noncoding RNA Mirt2 upregulates USP10 expression to suppress hepatic steatosis by sponging miR-34a-5p.","Gene","2019 Jun 5","Zhang B, Li H, Li D, Sun H, Li M, Hu H"
< "P52479-1","29698567","Ubiquitin-Specific Peptidase 10 (USP10) Inhibits Hepatic Steatosis, Insulin Resistance, and Inflammation Through Sirt6.","Hepatology (Baltimore, Md.)","2018 Nov","Luo P, Qin C, Zhu L, Fang C, Zhang Y, Zhang H, Pei F, Tian S, Zhu XY, Gong J, Mao Q, Xiao C, Su Y, Zheng H, Xu T, Lu J, Zhang J"
< "P52479-1","28852924","USP10 inhibits lung cancer cell growth and invasion by upregulating PTEN.","Molecular and cellular biochemistry","2018 Apr","Sun J, Li T, Zhao Y, Huang L, Sun H, Wu H, Jiang X"
< "P52479-1","27974222","USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells.","Stem cell reports","2016 Dec 13","Higuchi M, Kawamura H, Matsuki H, Hara T, Takahashi M, Saito S, Saito K, Jiang S, Naito M, Kiyonari H, Fujii M"
< "P52479-1","26393420","A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation.","eLife","2015 Sep 22","Li L, Martinez SS, Hu W, Liu Z, Tjian R"
< "P52479-1","18632802","Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3.","American journal of physiology. Renal physiology","2008 Oct","Boulkroun S, Ruffieux-Daidie D, Vitagliano JJ, Poirot O, Charles RP, Lagnaz D, Firsov D, Kellenberger S, Staub O"
< "Q61985-1","30287392","Mechanisms controlling the multistage post-translational processing of endogenous Nrf1alpha/TCF11 proteins to yield distinct isoforms within the coupled positive and negative feedback circuits.","Toxicology and applied pharmacology","2018 Dec 1","Xiang Y, Wang M, Hu S, Qiu L, Yang F, Zhang Z, Yu S, Pi J, Zhang Y"
< "Q61985-1","30268580","Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor.","Toxicology and applied pharmacology","2018 Dec 1","Xiang Y, Halin J, Fan Z, Hu S, Wang M, Qiu L, Zhang Z, Mattjus P, Zhang Y"
< "Q61985-1","29935181","Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice.","Biochemical and biophysical research communications","2018 Sep 3","Hou Y, Liu Z, Zuo Z, Gao T, Fu J, Wang H, Xu Y, Liu D, Yamamoto M, Zhu B, Zhang Y, Andersen ME, Zhang Q, Pi J"
6920a7621
> "Q78JT3-1","30063927","Single Nucleotide Polymorphisms of HAAO and IRX6 Genes as Risk Factors for Hypospadias.","The Journal of urology","2019 Feb","Kojima Y, Koguchi T, Mizuno K, Sato Y, Hoshi S, Hata J, Nishio H, Hashimoto D, Matsushita S, Suzuki K, Miyagawa S, Hui CC, Tanikawa C, Murakami Y, Yamada G, Hayashi Y, Matsuda K"
6924,6925c7625
< "Q66JX5-1","29982567","Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy.","Human molecular genetics","2018 Oct 1","Cabaud O, Roubin R, Comte A, Bascunana V, Serge A, Sedjai F, Birnbaum D, Rosnet O, Acquaviva C"
< "Q66JX5-1","12969958","FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice.","Blood","2004 Jan 1","Guasch G, Delaval B, Arnoulet C, Xie MJ, Xerri L, Sainty D, Birnbaum D, Pebusque MJ"
---
> "Q68FE2-1","19926846","Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.","Proceedings of the National Academy of Sciences of the United States of America","2009 Dec 8","Saitoh T, Fujita N, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T, Yamamoto N, Kawai T, Ishii K, Takeuchi O, Yoshimori T, Akira S"
6931c7631
< "Q5SUQ9-1","22531781","CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.","The EMBO journal","2012 May 16","Gu P, Min JN, Wang Y, Huang C, Peng T, Chai W, Chang S"
---
> "Q8CH25-1","17630952","A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.","The Biochemical journal","2007 Nov 1","Chan CW, Lee YB, Uney J, Flynn A, Tobias JH, Norman M"
6939,6941c7639,7643
< "O54830-1","12399423","Two placental hormones are agonists in stimulating megakaryocyte growth and differentiation.","Endocrinology","2002 Nov","Zhou B, Lum HE, Lin J, Linzer DI"
< "O54830-1","12040023","Reactivation of a hematopoietic endocrine program of pregnancy contributes to recovery from thrombocytopenia.","Molecular endocrinology (Baltimore, Md.)","2002 Jun","Bhattacharyya S, Lin J, Linzer DI"
< "Q80VP5-1","22821833","Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65.","Proteins","2012 Nov","Kogure H, Hikawa Y, Hagihara M, Tochio N, Koshiba S, Inoue Y, Guntert P, Kigawa T, Yokoyama S, Nameki N"
---
> "Q61164-1","30086769","CTCF maintains regulatory homeostasis of cancer pathways.","Genome biology","2018 Aug 7","Aitken SJ, Ibarra-Soria X, Kentepozidou E, Flicek P, Feig C, Marioni JC, Odom DT"
> "Q3TB92-1","30556363","Allergy inhibitory receptor-1 inhibits autoantibody production via upregulation of apoptotic debris clearance by macrophages.","International journal of rheumatic diseases","2018 Dec","Iizuka A, Segawa S, Kondo Y, Kaneko S, Yokosawa M, Furuyama K, Miki H, Tahara-Hanaoka S, Shibuya A, Tsuboi H, Goto D, Matsumoto I, Shibayama S, Sumida T"
> "Q3TB92-1","27932517","Allergin-1 inhibits TLR2-mediated mast cell activation and suppresses dermatitis.","International immunology","2016 Dec","Tsurusaki S, Tahara-Hanaoka S, Shibagaki S, Miyake S, Imai M, Shibayama S, Kubo M, Shibuya A"
> "Q3TB92-1","24552759","[Immunoglobulin-like receptor, allergin-1 regulates the activation of mast cells].","Arerugi = [Allergy]","2013 Nov","Tahara-Hanaoka S, Shibuya A"
> "Q810B9-1","22286174","Selective control of inhibitory synapse development by Slitrk3-PTPdelta trans-synaptic interaction.","Nature neuroscience","2012 Jan 29","Takahashi H, Katayama K, Sohya K, Miyamoto H, Prasad T, Matsumoto Y, Ota M, Yasuda H, Tsumoto T, Aruga J, Craig AM"
6944a7647,7652
> "O88508-1","12138111","A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.","The Journal of biological chemistry","2002 Oct 11","Chen T, Ueda Y, Xie S, Li E"
> "P70351-1","30689973","Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice.","Gastroenterology","2019 May","Grindheim JM, Nicetto D, Donahue G, Zaret KS"
> "P70351-1","29342143","Regulation of embryonic haematopoietic multipotency by EZH1.","Nature","2018 Jan 25","Vo LT, Kinney MA, Liu X, Zhang Y, Barragan J, Sousa PM, Jha DK, Han A, Cesana M, Shao Z, North TE, Orkin SH, Doulatov S, Xu J, Daley GQ"
> "Q9D2G5-1","27878645","The Synaptojanins in the murine small and large intestine.","Journal of bioenergetics and biomembranes","2016 Dec","Vazquez-Carretero MD, Carvajal AE, Serrano-Morales JM, Garcia-Miranda P, Ilundain AA, Peral MJ"
> "Q9D2G5-1","24103750","Analysis of an intronic promoter within Synj2.","Biochemical and biophysical research communications","2013 Nov 1","Planchart A"
> "Q9D2G5-1","21423608","A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.","PloS one","2011 Mar 15","Manji SS, Williams LH, Miller KA, Ooms LM, Bahlo M, Mitchell CA, Dahl HH"
6948a7657
> "P39054-1","30291191","Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy.","Proceedings of the National Academy of Sciences of the United States of America","2018 Oct 23","Buono S, Ross JA, Tasfaout H, Levy Y, Kretz C, Tayefeh L, Matson J, Guo S, Kessler P, Monia BP, Bitoun M, Ochala J, Laporte J, Cowling BS"
6956,6957c7665,7676
< "O88829-1","28808804","Identification of a new liver-specific c-type mRNA transcriptional variant for mouse ST3GAL5 (GM3/GM4 synthase).","Glycoconjugate journal","2017 Oct","Shishido F, Uemura S, Nitta T, Inokuchi JI"
< "Q8BKT8-1","23182369","Knockdown of UCHL5IP causes abnormalities in gamma-tubulin localisation, spindle organisation and chromosome alignment in mouse oocyte meiotic maturation.","Reproduction, fertility, and development","2013","Wang YP, Qi ST, Wei Y, Ge ZJ, Chen L, Hou Y, Ouyang YC, Schatten H, Zhao JG, Sun QY"
---
> "Q8K2P7-1","29065407","Hypoxic Stress Upregulates the Expression of Slc38a1 in Brown Adipocytes via Hypoxia-Inducible Factor-1alpha.","Pharmacology","2018","Horie T, Fukasawa K, Iezaki T, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Hinoi E"
> "Q8K2P7-1","28095293","MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.","eLife","2017 Jan 17","Walker LJ, Summers DW, Sasaki Y, Brace EJ, Milbrandt J, DiAntonio A"
> "Q8K2P7-1","27373508","Regulation of amino acid transporters in pluripotent cell populations in the embryo and in culture; novel roles for sodium-coupled neutral amino acid transporters.","Mechanisms of development","2016 Aug","Tan BSN, Rathjen PD, Harvey AJ, Gardner DK, Rathjen J"
> "Q8K2P7-1","25957749","Upregulation of Slc38a1 Gene Along with Promotion of Neurosphere Growth and Subsequent Neuronal Specification in Undifferentiated Neural Progenitor Cells Exposed to Theanine.","Neurochemical research","2016 Feb","Takarada T, Ogura M, Nakamichi N, Kakuda T, Nakazato R, Kokubo H, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y"
> "Q8K2P7-1","25673846","Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Feb 11","Jin LW, Horiuchi M, Wulff H, Liu XB, Cortopassi GA, Erickson JD, Maezawa I"
> "Q6P1B3-1","27349870","Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.","Biochemical and biophysical research communications","2016 Sep 2","Biswas S, Adrian M, Weber J, Evdokimov K, Winkler M, Geraud C"
> "Q6P1B3-1","26188512","Counter-regulation of the ligand-receptor pair Leda-1/Pianp and Pilralpha during the LPS-mediated immune response of murine macrophages.","Biochemical and biophysical research communications","2015 Sep 4","Biswas S, Adrian M, Evdokimov K, Schledzewski K, Weber J, Winkler M, Goerdt S, Geraud C"
> "Q6P1B3-1","23558288","Proteolytic cleavage of LEDA-1/PIANP by furin-like proprotein convertases precedes its plasma membrane localization.","Biochemical and biophysical research communications","2013 Apr 26","Evdokimov K, Biswas S, Adrian M, Weber J, Schledzewski K, Winkler M, Goerdt S, Geraud C"
> "Q6P1B3-1","21241660","PANP is a novel O-glycosylated PILRalpha ligand expressed in neural tissues.","Biochemical and biophysical research communications","2011 Feb 18","Kogure A, Shiratori I, Wang J, Lanier LL, Arase H"
> "Q60929-1","29054930","The transcription factor MEF2A fine-tunes gene expression in the atrial and ventricular chambers of the adult heart.","The Journal of biological chemistry","2017 Dec 22","Medrano JL, Naya FJ"
> "Q60929-1","28965945","AKT2 deficiency induces retardation of myocyte development through EndoG-MEF2A signaling in mouse heart.","Biochemical and biophysical research communications","2017 Dec 2","Chen D, Chen F, Xu Y, Zhang Y, Li Z, Zhang H, Pan T, Su Y, Wan M, Wang X, Ye J"
> "Q60929-1","28901289","Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D.","eLife","2017 Sep 13","Chang CW, Wilkerson JR, Hale CF, Gibson JR, Huber KM"
6968a7688
> "Q8BUE7-1","15314156","MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.","Molecular and cellular biology","2004 Sep","Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, Yamamoto T, Saito Y, Nakamura M"
7001a7722,7723
> "O54714-1","27845432","Protein Inhibitor of Activated STAT3 Suppresses Oxidized LDL-induced Cell Responses during Atherosclerosis in Apolipoprotein E-deficient Mice.","Scientific reports","2016 Nov 15","Wang R, Zhang Y, Xu L, Lin Y, Yang X, Bai L, Chen Y, Zhao S, Fan J, Cheng X, Liu E"
> "O54714-1","25713074","Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).","The Journal of biological chemistry","2015 Apr 10","Siatecka M, Soni S, Planutis A, Bieker JJ"
7010c7732
< "Q7TQ62-1","15063725","Functional characterization of podocan, a member of a new class in the small leucine-rich repeat protein family.","FEBS letters","2004 Apr 9","Shimizu-Hirota R, Sasamura H, Kuroda M, Kobayashi E, Saruta T"
---
> "O35892-1","11471051","Source and component genes of a 6-200 Mb gene cluster in the house mouse.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Aug","Weichenhan D, Kunze B, Winking H, van Geel M, Osoegawa K, de Jong PJ, Traut W"
7012,7013d7733
< "Q3URD3-1","22180652","Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum.","American journal of physiology. Heart and circulatory physiology","2012 Mar 1","Nader M, Westendorp B, Hawari O, Salih M, Stewart AF, Leenen FH, Tuana BS"
< "Q3URD3-1","21785580","Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice.","Experimental diabetes research","2011","Chen X, Ding H"
7016,7017d7735
< "A2AMT1-1","29196765","Aquaporin 0 Modulates Lens Gap Junctions in the Presence of Lens-Specific Beaded Filament Proteins.","Investigative ophthalmology &amp; visual science","2017 Dec 1","Kumari S, Gao J, Mathias RT, Sun X, Eswaramoorthy A, Browne N, Zhang N, Varadaraj K"
< "A2AMT1-1","27559293","Expression of the type VI intermediate filament proteins CP49 and filensin in the mouse lens epithelium.","Molecular vision","2016","FitzGerald P, Sun N, Shibata B, Hess JF"
7018a7737,7738
> "Q9D385-1","29718757","ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure.","Molecular biology of the cell","2018 Jul 1","Moye AR, Singh R, Kimler VA, Dilan TL, Munezero D, Saravanan T, Goldberg AFX, Ramamurthy V"
> "Q9D385-1","18234692","BART is essential for nuclear retention of STAT3.","International immunology","2008 Mar","Muromoto R, Sekine Y, Imoto S, Ikeda O, Okayama T, Sato N, Matsuda T"
7019a7740
> "Q9WV38-1","29259131","Identification of essential amino acids for glucose transporter 5 (GLUT5)-mediated fructose transport.","The Journal of biological chemistry","2018 Feb 9","Ebert K, Ewers M, Bisha I, Sander S, Rasputniac T, Daniel H, Antes I, Witt H"
7033,7034d7753
< "A2ASZ8-1","28588221","Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway that might be involved in muscle thermogenesis.","Scientific reports","2017 Jun 6","Nakao R, Shimba S, Oishi K"
< "A2ASZ8-1","21296886","Inactivation of the mitochondrial carrier SLC25A25 (ATP-Mg2+/Pi transporter) reduces physical endurance and metabolic efficiency in mice.","The Journal of biological chemistry","2011 Apr 1","Anunciado-Koza RP, Zhang J, Ukropec J, Bajpeyi S, Koza RA, Rogers RC, Cefalu WT, Mynatt RL, Kozak LP"
7036a7756
> "O70477-1","30337366","Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites.","The Journal of biological chemistry","2018 Dec 14","Volkel S, Stielow B, Finkernagel F, Berger D, Stiewe T, Nist A, Suske G"
7037a7758
> "P35639-1","30894532","ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.","Nature communications","2019 Mar 20","Cao Y, Trillo-Tinoco J, Sierra RA, Anadon C, Dai W, Mohamed E, Cen L, Costich TL, Magliocco A, Marchion D, Klar R, Michel S, Jaschinski F, Reich RR, Mehrotra S, Cubillos-Ruiz JR, Munn DH, Conejo-Garcia JR, Rodriguez PC"
7039a7761,7765
> "O54946-1","21972064","Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.","Developmental dynamics : an official publication of the American Association of Anatomists","2011 Nov","Watson ED, Hughes M, Simmons DG, Natale DR, Sutherland AE, Cross JC"
> "O54946-1","19777589","Neural stem cell self-renewal requires the Mrj co-chaperone.","Developmental dynamics : an official publication of the American Association of Anatomists","2009 Oct","Watson ED, Mattar P, Schuurmans C, Cross JC"
> "O54946-1","18373498","The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells.","The Biochemical journal","2008 Jul 15","Zhang Y, Yang Z, Cao Y, Zhang S, Li H, Huang Y, Ding YQ, Liu X"
> "Q8BGB7-1","24236849","Analysis of quantitative trait loci in mice suggests a role of Enoph1 in stress reactivity.","Journal of neurochemistry","2014 Mar","Barth A, Bilkei-Gorzo A, Drews E, Otte DM, Diaz-Lacava A, Varadarajulu J, Turck CW, Wienker TF, Zimmer A"
> "Q8BGB7-1","19139748","Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways.","Molecular psychiatry","2010 Jul","Ditzen C, Varadarajulu J, Czibere L, Gonik M, Targosz BS, Hambsch B, Bettecken T, Kessler MS, Frank E, Bunck M, Teplytska L, Erhardt A, Holsboer F, Muller-Myhsok B, Landgraf R, Turck CW"
7051d7776
< "Q5RKZ7-1","15862276","The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis.","Molecular genetics and metabolism","2005 May","Reiss J, Bonin M, Schwegler H, Sass JO, Garattini E, Wagner S, Lee HJ, Engel W, Riess O, Schwarz G"
7061a7787
> "Q6ZPF3-1","30817801","Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype.","PLoS genetics","2019 Feb","Charron Y, Willert J, Lipkowitz B, Kusecek B, Herrmann BG, Bauer H"
7063a7790
> "Q80UW0-1","15499561","Differential expression of heparan sulfate 6-O-sulfotransferase isoforms in the mouse embryo suggests distinctive roles during organogenesis.","Developmental dynamics : an official publication of the American Association of Anatomists","2004 Dec","Sedita J, Izvolsky K, Cardoso WV"
7069a7797
> "Q793I8-1","16643855","A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling.","Biochemical and biophysical research communications","2006 Jun 9","Minoda Y, Saeki K, Aki D, Takaki H, Sanada T, Koga K, Kobayashi T, Takaesu G, Yoshimura A"
7083a7812
> "P98197-1","30355768","Phospholipid flippases enable precursor B cells to flee engulfment by macrophages.","Proceedings of the National Academy of Sciences of the United States of America","2018 Nov 27","Segawa K, Yanagihashi Y, Yamada K, Suzuki C, Uchiyama Y, Nagata S"
7085,7087c7814,7821
< "P08923-1","22079349","Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis.","Pharmacology, biochemistry, and behavior","2012 Jan","Weiss JB, Xue C, Benice T, Xue L, Morris SW, Raber J"
< "P08923-1","18854310","Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis.","The Journal of biological chemistry","2008 Dec 5","Li J, Niu XL, Madamanchi NR"
< "P08923-1","2357970","The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator.","The EMBO journal","1990 Jul","Bernards A, de la Monte SM"
---
> "Q69ZN7-1","20571050","Myoferlin regulation by NFAT in muscle injury, regeneration and repair.","Journal of cell science","2010 Jul 15","Demonbreun AR, Lapidos KA, Heretis K, Levin S, Dale R, Pytel P, Svensson EC, McNally EM"
> "Q69ZN7-1","20008164","Myoferlin is required for insulin-like growth factor response and muscle growth.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2010 Apr","Demonbreun AR, Posey AD, Heretis K, Swaggart KA, Earley JU, Pytel P, McNally EM"
> "Q69ZN7-1","17702744","Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.","The Journal of biological chemistry","2007 Oct 19","Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC"
> "Q69ZN7-1","16280346","Normal myoblast fusion requires myoferlin.","Development (Cambridge, England)","2005 Dec","Doherty KR, Cave A, Davis DB, Delmonte AJ, Posey A, Earley JU, Hadhazy M, McNally EM"
> "Q69ZN7-1","11959863","Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.","The Journal of biological chemistry","2002 Jun 21","Davis DB, Doherty KR, Delmonte AJ, McNally EM"
> "Q32MG2-1","12204287","Nurit, a novel leucine-zipper protein, expressed uniquely in the spermatid flower-like structure.","Mechanisms of development","2002 Sep","Feige E, Chen A, Motro B"
> "Q8VCD7-1","29438700","Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.","Cancer cell","2018 Feb 12","Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MR, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, Treitschke S, Dorken B, Speck C, Mallette FA, Zon LI, Holmen SL, Peeper DS, Samuels Y, Schmitt CA, Lee S"
> "Q8VCD7-1","30537731","circZMYM2 Competed Endogenously with miR-335-5p to Regulate JMJD2C in Pancreatic Cancer.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2018","An Y, Cai H, Zhang Y, Liu S, Duan Y, Sun D, Chen X, He X"
7100a7835,7836
> "P51954-1","28982183","NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between alpha-Adducin and Myosin X.","PloS one","2017","Brieno-Enriquez MA, Moak SL, Holloway JK, Cohen PE"
> "P51954-1","27760328","Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1gamma-WAPL Axis in the Mouse.","Cell reports","2016 Oct 18","Brieno-Enriquez MA, Moak SL, Toledo M, Filter JJ, Gray S, Barbero JL, Cohen PE, Holloway JK"
7103,7105d7838
< "O88576-1","26240152","Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin.","The Journal of biological chemistry","2015 Oct 2","Fairweather SJ, Broer A, Subramanian N, Tumer E, Cheng Q, Schmoll D, O'Mara ML, Broer S"
< "O88576-1","19478081","Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3.","The Journal of biological chemistry","2009 Jul 24","Singer D, Camargo SM, Huggel K, Romeo E, Danilczyk U, Kuba K, Chesnov S, Caron MG, Penninger JM, Verrey F"
< "O88576-1","15121838","Hypertension and impaired glycine handling in mice lacking the orphan transporter XT2.","Molecular and cellular biology","2004 May","Quan H, Athirakul K, Wetsel WC, Torres GE, Stevens R, Chen YT, Coffman TM, Caron MG"
7110a7844,7846
> "Q6ZQM0-1","24114843","Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation.","The Journal of biological chemistry","2013 Nov 22","Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D"
> "Q6ZQM0-1","19138581","CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.","Current biology : CB","2009 Jan 13","Ahmed AU, Moulin M, Coumailleau F, Wong WW, Miasari M, Carter H, Silke J, Cohen-Tannoudji M, Vince JE, Vaux DL"
> "Q6ZQM0-1","15229288","Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.","Molecular biology of the cell","2004 Oct","Coumailleau F, Das V, Alcover A, Raposo G, Vandormael-Pournin S, Le Bras S, Baldacci P, Dautry-Varsat A, Babinet C, Cohen-Tannoudji M"
7111a7848
> "Q91V24-1","12917409","ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux.","The Journal of biological chemistry","2003 Oct 31","Wang N, Lan D, Gerbod-Giannone M, Linsel-Nitschke P, Jehle AW, Chen W, Martinez LO, Tall AR"
7113,7120c7850,7852
< "Q8C2S5-1","29470856","Leishmania donovani inhibits ferroportin translation by modulating FBXL5-IRP2 axis for its growth within host macrophages.","Cellular microbiology","2018 Jul","Das NK, Sandhya S, G VV, Kumar R, Singh AK, Bal SK, Kumari S, Mukhopadhyay CK"
< "Q8C2S5-1","28714470","Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.","Nature communications","2017 Jul 17","Muto Y, Nishiyama M, Nita A, Moroishi T, Nakayama KI"
< "Q8C2S5-1","28069738","FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.","Molecular and cellular biology","2017 Apr 15","Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI"
< "Q8C2S5-1","24508277","F-box and leucine-rich repeat protein 5 (FBXL5): sensing intracellular iron and oxygen.","Journal of inorganic biochemistry","2014 Apr","Ruiz JC, Bruick RK"
< "Q91V57-1","28346224","Mutant alpha2-chimaerin signals via bidirectional ephrin pathways in Duane retraction syndrome.","The Journal of clinical investigation","2017 May 1","Nugent AA, Park JG, Wei Y, Tenney AP, Gilette NM, DeLisle MM, Chan WM, Cheng L, Engle EC"
< "Q91V57-1","17719550","Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling.","Cell","2007 Aug 24","Iwasato T, Katoh H, Nishimaru H, Ishikawa Y, Inoue H, Saito YM, Ando R, Iwama M, Takahashi R, Negishi M, Itohara S"
< "Q91V57-1","16446429","The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology.","Proceedings of the National Academy of Sciences of the United States of America","2006 Feb 7","Buttery P, Beg AA, Chih B, Broder A, Mason CA, Scheiffele P"
< "Q91V57-1","15447672","Chimaerins act downstream from neurotrophins in overcoming the inhibition of neurite outgrowth produced by myelin-associated glycoprotein.","Journal of neurochemistry","2004 Oct","Mizuno T, Yamashita T, Tohyama M"
---
> "Q6KCD5-1","28041881","Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration.","Neuron","2017 Jan 18","van den Berg DLC, Azzarelli R, Oishi K, Martynoga B, Urban N, Dekkers DHW, Demmers JA, Guillemot F"
> "Q6KCD5-1","27606604","Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.","PLoS biology","2016 Sep","Santos R, Kawauchi S, Jacobs RE, Lopez-Burks ME, Choi H, Wikenheiser J, Hallgrimsson B, Jamniczky HA, Fraser SE, Lander AD, Calof AL"
> "Q6KCD5-1","19763162","Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome.","PLoS genetics","2009 Sep","Kawauchi S, Calof AL, Santos R, Lopez-Burks ME, Young CM, Hoang MP, Chua A, Lao T, Lechner MS, Daniel JA, Nussenzweig A, Kitzes L, Yokomori K, Hallgrimsson B, Lander AD"
7122,7126c7854
< "Q60604-1","28389691","Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism.","Calcified tissue international","2017 Aug","Cao Y, Wang Y, Sprangers S, Picavet DI, Glogauer M, McCulloch CA, Everts V"
< "Q60604-1","26642432","Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1.","Experimental &amp; molecular medicine","2015 Dec 18","Song MK, Lee ZH, Kim HH"
< "Q60604-1","25681458","Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2015 Jun","Jiang H, Wang Y, Viniegra A, Sima C, McCulloch CA, Glogauer M"
< "Q60604-1","25275604","The actin binding protein adseverin regulates osteoclastogenesis.","PloS one","2014","Hassanpour S, Jiang H, Wang Y, Kuiper JW, Glogauer M"
< "Q60604-1","11883943","Dioxin-induced adseverin expression in the mouse thymus is strictly regulated and dependent on the aryl hydrocarbon receptor.","Biochemical and biophysical research communications","2002 Mar 15","Svensson C, Silverstone AE, Lai ZW, Lundberg K"
---
> "Q9ERD6-1","17462626","Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase.","Experimental cell research","2007 Jul 1","Ceriani M, Scandiuzzi C, Amigoni L, Tisi R, Berruti G, Martegani E"
7130a7859,7861
> "Q9WVG9-1","28609438","PEG3 control on the mammalian MSL complex.","PloS one","2017","Ye A, Kim H, Kim J"
> "Q9WVG9-1","21217699","Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1.","Nature structural &amp; molecular biology","2011 Feb","Kadlec J, Hallacli E, Lipp M, Holz H, Sanchez-Weatherby J, Cusack S, Akhtar A"
> "Q9WVG9-1","11668396","Analysis of Mid1, Hccs, Arhgap6, and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf) mutant mice.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Oct","Cormier TA, Prakash SK, Magner DB, Zoghbi HY, Van den Veyver IB"
7133,7137d7863
< "Q9WVS8-1","29723698","ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice.","Biochimica et biophysica acta. Molecular basis of disease","2018 Aug","Deng Y, Lei T, Li H, Mo X, Wang Z, Ou H"
< "Q9WVS8-1","29986870","The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis.","Development (Cambridge, England)","2018 Jul 26","Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E"
< "Q9WVS8-1","29159830","ERK5 plays an essential role in gestational beta-cell proliferation.","Cell proliferation","2018 Jun","Chen C, Wu S, Lin X, Wu D, Fischbach S, Xiao X"
< "Q9WVS8-1","28887535","Metabolic stress-induced cardiomyopathy is caused by mitochondrial dysfunction due to attenuated Erk5 signaling.","Nature communications","2017 Sep 8","Liu W, Ruiz-Velasco A, Wang S, Khan S, Zi M, Jungmann A, Dolores Camacho-Munoz M, Guo J, Du G, Xie L, Oceandy D, Nicolaou A, Galli G, Muller OJ, Cartwright EJ, Ji Y, Wang X"
< "Q9WVS8-1","12093914","Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.","Proceedings of the National Academy of Sciences of the United States of America","2002 Jul 9","Regan CP, Li W, Boucher DM, Spatz S, Su MS, Kuida K"
7143,7145d7868
< "P41438-1","15579899","Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates.","The Journal of biological chemistry","2005 Feb 18","Liu M, Ge Y, Cabelof DC, Aboukameel A, Heydari AR, Mohammad R, Matherly LH"
< "P41438-1","12832086","Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility.","Biochimica et biophysica acta","2003 Jun 27","Zhao R, Wang Y, Gao F, Goldman ID"
< "Q91YI4-1","30576947","Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and beta-arrestin 2 in inflammatory macrophages.","Molecular immunology","2019 Feb","Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ"
7153,7158c7876,7880
< "Q8BIF0-1","29791026","CD99L2 deficiency inhibits leukocyte entry into the central nervous system and ameliorates neuroinflammation.","Journal of leukocyte biology","2018 Oct","Samus M, Seelige R, Schafer K, Sorokin L, Vestweber D"
< "Q8BIF0-1","26321243","CD99-like 2 (CD99L2)-deficient mice are defective in the acute inflammatory response.","Experimental and molecular pathology","2015 Dec","Rutledge NS, Weber EW, Winger R, Tourtellotte WG, Park SH, Muller WA"
< "Q8BIF0-1","23338758","Effect of shRNA targeting mouse CD99L2 gene in a murine B cell lymphoma in vitro and in vivo.","Oncology reports","2013 Apr","Liu F, Zhang G, Liu F, Zhou X, Chen X, Han X, Wu Z, Zhao T"
< "Q8BIF0-1","23293350","Cutting edge: Endothelial-specific gene ablation of CD99L2 impairs leukocyte extravasation in vivo.","Journal of immunology (Baltimore, Md. : 1950)","2013 Feb 1","Seelige R, Natsch C, Marz S, Jing D, Frye M, Butz S, Vestweber D"
< "Q8BIF0-1","18163232","The murine CD99-related molecule CD99-like 2 (CD99L2) is an adhesion molecule involved in the inflammatory response.","Cell communication &amp; adhesion","2007 Sep-Oct","Schenkel AR, Dufour EM, Chew TW, Sorg E, Muller WA"
< "Q8BIF0-1","17344467","A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo.","Blood","2007 Jun 15","Bixel MG, Petri B, Khandoga AG, Khandoga A, Wolburg-Buchholz K, Wolburg H, Marz S, Krombach F, Vestweber D"
---
> "Q8CBR1-1","28461473","ILDR1 is important for paracellular water transport and urine concentration mechanism.","Proceedings of the National Academy of Sciences of the United States of America","2017 May 16","Gong Y, Himmerkus N, Sunq A, Milatz S, Merkel C, Bleich M, Hou J"
> "Q8CBR1-1","25822906","Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.","PloS one","2015","Higashi T, Katsuno T, Kitajiri S, Furuse M"
> "Q8CBR1-1","25217574","ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.","Human molecular genetics","2015 Feb 1","Morozko EL, Nishio A, Ingham NJ, Chandra R, Fitzgerald T, Martelletti E, Borck G, Wilson E, Riordan GP, Wangemann P, Forge A, Steel KP, Liddle RA, Friedman TB, Belyantseva IA"
> "Q8CBR1-1","23863714","Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion.","The Journal of clinical investigation","2013 Aug","Chandra R, Wang Y, Shahid RA, Vigna SR, Freedman NJ, Liddle RA"
> "Q8CBR1-1","23239027","Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.","Journal of cell science","2013 Feb 15","Higashi T, Tokuda S, Kitajiri S, Masuda S, Nakamura H, Oda Y, Furuse M"
7163,7170c7885,7890
< "Q8C167-1","23321636","Trans-Golgi network morphology and sorting is regulated by prolyl-oligopeptidase-like protein PREPL and the AP-1 complex subunit mu1A.","Journal of cell science","2013 Mar 1","Radhakrishnan K, Baltes J, Creemers JW, Schu P"
< "Q8R1X6-1","28324774","Methylation changes of SIRT1, KLF4, DAPK1 and SPG20 in B-lymphocytes derived from follicular and diffuse large B-cell lymphoma.","Leukemia research","2017 Jun","Frazzi R, Zanetti E, Pistoni M, Tamagnini I, Valli R, Braglia L, Merli F"
< "Q8R1X6-1","27112432","Three cases of Troyer syndrome in two families of Filipino descent.","American journal of medical genetics. Part A","2016 Jul","Butler S, Helbig KL, Alcaraz W, Seaver LH, Hsieh DT, Rohena L"
< "Q8R1X6-1","24523286","The role of spartin and its novel ubiquitin binding region in DALIS occurrence.","Molecular biology of the cell","2014 Apr","Karlsson AB, Washington J, Dimitrova V, Hooper C, Shekhtman A, Bakowska JC"
< "Q8R1X6-1","22982304","Are alsin and spartin novel interaction partners?","Biochemical and biophysical research communications","2012 Oct 12","Cobanoglu G, Ozansoy M, Basak AN"
< "Q8R1X6-1","22619377","Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling.","Human molecular genetics","2012 Aug 15","Renvoise B, Stadler J, Singh R, Bakowska JC, Blackstone C"
< "Q8R1X6-1","21559443","SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis.","PloS one","2011 Apr 29","Joshi DC, Bakowska JC"
< "Q8R1X6-1","16036216","The Troyer syndrome (SPG20) protein spartin interacts with Eps15.","Biochemical and biophysical research communications","2005 Sep 9","Bakowska JC, Jenkins R, Pendleton J, Blackstone C"
---
> "O88838-1","28270450","Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.","Blood","2017 May 4","Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK"
> "O88838-1","20561531","Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.","Journal of molecular biology","2010 Aug 20","Filippakopoulos P, Low A, Sharpe TD, Uppenberg J, Yao S, Kuang Z, Savitsky P, Lewis RS, Nicholson SE, Norton RS, Bullock AN"
> "O88838-1","20603330","The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation.","The Journal of cell biology","2010 Jul 12","Kuang Z, Lewis RS, Curtis JM, Zhan Y, Saunders BM, Babon JJ, Kolesnik TB, Low A, Masters SL, Willson TA, Kedzierski L, Yao S, Handman E, Norton RS, Nicholson SE"
> "O88838-1","17088318","Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops.","Protein science : a publication of the Protein Society","2006 Dec","Yao S, Liu MS, Masters SL, Zhang JG, Babon JJ, Nicola NA, Nicholson SE, Norton RS"
> "O88838-1","16369487","The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.","Nature structural &amp; molecular biology","2006 Jan","Masters SL, Yao S, Willson TA, Zhang JG, Palmer KR, Smith BJ, Babon JJ, Nicola NA, Norton RS, Nicholson SE"
> "O88838-1","15964819","Genetic deletion of murine SPRY domain-containing SOCS box protein 2 (SSB-2) results in very mild thrombocytopenia.","Molecular and cellular biology","2005 Jul","Masters SL, Palmer KR, Stevenson WS, Metcalf D, Viney EM, Sprigg NS, Alexander WS, Nicola NA, Nicholson SE"
7173a7894,7896
> "Q9QYS9-1","30628007","Identification of Novel Binding Partners for Transcription Factor Emx2.","The protein journal","2019 Feb","Groves JA, Gillman C, DeLay CN, Kroll TT"
> "Q9QYS9-1","29021242","Autogenous cross-regulation of Quaking mRNA processing and translation balances Quaking functions in splicing and translation.","Genes &amp; development","2017 Sep 15","Fagg WS, Liu N, Fair JH, Shiue L, Katzman S, Donohue JP, Ares M Jr"
> "Q9QYS9-1","29021239","An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling.","Genes &amp; development","2017 Sep 15","Hayakawa-Yano Y, Suyama S, Nogami M, Yugami M, Koya I, Furukawa T, Zhou L, Abe M, Sakimura K, Takebayashi H, Nakanishi A, Okano H, Yano M"
7175a7899
> "P48540-1","30651543","Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback.","Nature communications","2019 Jan 16","Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D"
7181c7905
< "Q91YP6-1","22177965","The C-terminal polyproline-containing region of ELMO contributes to an increase in the life-time of the ELMO-DOCK complex.","Biochimie","2012 Mar","Sevajol M, Reiser JB, Chouquet A, Perard J, Ayala I, Gans P, Kleman JP, Housset D"
---
> "P37242-1","29753845","Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling.","Toxicology letters","2018 Sep 15","Yu Z, Han Y, Shen R, Huang K, Xu YY, Wang QN, Zhou SS, Xu DX, Tao FB"
7185a7910,7913
> "Q9JJ57-1","20678225","Roles of KChIP1 in the regulation of GABA-mediated transmission and behavioral anxiety.","Molecular brain","2010 Aug 2","Xia K, Xiong H, Shin Y, Wang D, Deerinck T, Takahashi H, Ellisman MH, Lipton SA, Tong G, Descalzi G, Zhang D, Zhuo M, Zhang Z"
> "Q9JJ57-1","17640927","The aromatic cluster in KCHIP1b affects Kv4 inactivation gating.","The Journal of physiology","2007 Sep 15","Van Hoorick D, Raes A, Snyders DJ"
> "Q9JJ57-1","15363885","Differential distribution of KChIPs mRNAs in adult mouse brain.","Brain research. Molecular brain research","2004 Sep 28","Xiong H, Kovacs I, Zhang Z"
> "Q9JJ57-1","14572458","Differential modulation of Kv4 kinetics by KCHIP1 splice variants.","Molecular and cellular neurosciences","2003 Oct","Van Hoorick D, Raes A, Keysers W, Mayeur E, Snyders DJ"
7186a7915,7918
> "Q8BVK9-1","11471051","Source and component genes of a 6-200 Mb gene cluster in the house mouse.","Mammalian genome : official journal of the International Mammalian Genome Society","2001 Aug","Weichenhan D, Kunze B, Winking H, van Geel M, Osoegawa K, de Jong PJ, Traut W"
> "Q3TDN0-1","18395198","Disp1 regulates growth of mammalian long bones through the control of Ihh distribution.","Developmental biology","2008 May 15","Tsiairis CD, McMahon AP"
> "Q3TDN0-1","12421714","Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling.","Development (Cambridge, England)","2002 Dec","Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT"
> "Q3TDN0-1","12372258","Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.","Current biology : CB","2002 Sep 17","Caspary T, Garcia-Garcia MJ, Huangfu D, Eggenschwiler JT, Wyler MR, Rakeman AS, Alcorn HL, Anderson KV"
7198a7931,7932
> "Q80U16-1","27269051","Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.","eLife","2016 Jun 8","Zhao B, Wu Z, Muller U"
> "Q80U16-1","25588844","Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.","Journal of cell science","2015 Mar 1","Gao K, Tang W, Li Y, Zhang P, Wang D, Yu L, Wang C, Wu D"
7202a7937
> "Q8CBW3-1","26428302","The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.","Cell communication and signaling : CCS","2015 Oct 1","Sekino S, Kashiwagi Y, Kanazawa H, Takada K, Baba T, Sato S, Inoue H, Kojima M, Tani K"
7210,7213c7945
< "Q60819-1","30926899","Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.","Nature communications","2019 Mar 29","Niogret C, Miah SMS, Rota G, Fonta NP, Wang H, Held W, Birchmeier W, Sexl V, Yang W, Vivier E, Ho PC, Brossay L, Guarda G"
< "Q3UWA6-1","29367634","Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens.","Scientific reports","2018 Jan 24","Amarachintha S, Harmel-Laws E, Steinbrecher KA"
< "Q3UWA6-1","28916678","GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.","Cancer research","2017 Sep 15","Li P, Wuthrick E, Rappaport JA, Kraft C, Lin JE, Marszalowicz G, Snook AE, Zhan T, Hyslop TM, Waldman SA"
< "Q3UWA6-1","26773096","Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.","Cancer research","2016 Jan 15","Lin JE, Colon-Gonzalez F, Blomain E, Kim GW, Aing A, Stoecker B, Rock J, Snook AE, Zhan T, Hyslop TM, Tomczak M, Blumberg RS, Waldman SA"
---
> "Q8VDL9-1","29371181","Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells.","Blood","2018 Apr 19","Shima H, Takamatsu-Ichihara E, Shino M, Yamagata K, Katsumoto T, Aikawa Y, Fujita S, Koseki H, Kitabayashi I"
7225a7958,7963
> "Q9ET39-1","29305520","Soluble SLAMF6 Receptor Induces Strong CD8(+) T-cell Effector Function and Improves Anti-Melanoma Activity In Vivo.","Cancer immunology research","2018 Feb","Eisenberg G, Engelstein R, Geiger-Maor A, Hajaj E, Merims S, Frankenburg S, Uzana R, Rutenberg A, Machlenkin A, Frei G, Peretz T, Lotem M"
> "Q9ET39-1","28904129","T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.","Journal of immunology (Baltimore, Md. : 1950)","2017 Oct 15","Radomir L, Cohen S, Kramer MP, Bakos E, Lewinsky H, Barak A, Porat Z, Bucala R, Stepensky P, Becker-Herman S, Shachar I"
> "Q9ET39-1","28373584","Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions.","Journal of immunology (Baltimore, Md. : 1950)","2017 May 15","Baglaenko Y, Cruz Tleugabulova M, Gracey E, Talaei N, Manion KP, Chang NH, Ferri DM, Mallevaey T, Wither JE"
> "Q9ET39-1","27223891","CRISPR-Mediated Slamf1Delta/Delta Slamf5Delta/Delta Slamf6Delta/Delta Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects.","PloS one","2016","Hu JK, Crampton JC, Locci M, Crotty S"
> "Q9ET39-1","26878112","A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.","Nature immunology","2016 Apr","Wu N, Zhong MC, Roncagalli R, Perez-Quintero LA, Guo H, Zhang Z, Lenoir C, Dong Z, Latour S, Veillette A"
> "Q9ET39-1","15879084","Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions.","Journal of immunology (Baltimore, Md. : 1950)","2005 May 15","Howie D, Laroux FS, Morra M, Satoskar AR, Rosas LE, Faubion WA, Julien A, Rietdijk S, Coyle AJ, Fraser C, Terhorst C"
7227a7966,7967
> "B2RPY5-1","29386106","Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.","Cell reports","2018 Jan 30","Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S"
> "B2RPY5-1","29222391","The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.","Development (Cambridge, England)","2018 Jan 8","Hwang SH, White KA, Somatilaka BN, Shelton JM, Richardson JA, Mukhopadhyay S"
7230a7971
> "Q9R1K7-1","29290584","CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.","Developmental cell","2018 Jan 8","Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R"
7234a7976,7980
> "Q7TMK9-1","28436985","Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.","Nature genetics","2017 Jun","Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, Kwon JA, Meydan C, Perales-Paton J, Arshi A, Gonen M, Famulare C, Patel M, Paietta E, Tallman MS, Lu Y, Glass J, Garret-Bakelman FE, Melnick A, Levine R, Al-Shahrour F, Jaras M, Hacohen N, Hwang A, Garippa R, Lengner CJ, Armstrong SA, Cerchietti L, Cowley GS, Root D, Doench J, Leslie C, Ebert BL, Kharas MG"
> "Q7TMK9-1","27732855","The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting.","Cell reports","2016 Oct 11","Santangelo L, Giurato G, Cicchini C, Montaldo C, Mancone C, Tarallo R, Battistelli C, Alonzi T, Weisz A, Tripodi M"
> "Q7TMK9-1","27392095","HnRNP Q Has a Suppressive Role in the Translation of Mouse Cryptochrome1.","PloS one","2016","Lim I, Jung Y, Kim DY, Kim KT"
> "Q7TMK9-1","26658614","hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation.","Molecular biology of the cell","2016 Feb 1","Williams KR, McAninch DS, Stefanovic S, Xing L, Allen M, Li W, Feng Y, Mihailescu MR, Bassell GJ"
> "Q7TMK9-1","11994298","Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding protein.","The Journal of biological chemistry","2002 Jul 12","Hresko RC, Mueckler M"
7241a7988
> "E9Q9K8-1","26563778","AKAP6 inhibition impairs myoblast differentiation and muscle regeneration: Positive loop between AKAP6 and myogenin.","Scientific reports","2015 Nov 13","Lee SW, Won JY, Yang J, Lee J, Kim SY, Lee EJ, Kim HS"
7243a7991,7992
> "Q8C0N0-1","15289607","The mouse kinome: discovery and comparative genomics of all mouse protein kinases.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G"
> "Q8VDP4-1","30415949","An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity.","Molecular cell","2018 Dec 20","Krzysiak TC, Thomas L, Choi YJ, Auclair S, Qian Y, Luan S, Krasnow SM, Thomas LL, Koharudin LMI, Benos PV, Marks DL, Gronenborn AM, Thomas G"
7250d7998
< "Q80YA3-1","24599962","Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics.","The Journal of biological chemistry","2014 Apr 18","Baba T, Kashiwagi Y, Arimitsu N, Kogure T, Edo A, Maruyama T, Nakao K, Nakanishi H, Kinoshita M, Frohman MA, Yamamoto A, Tani K"
7251a8000
> "Q9QYN3-1","28867182","Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma.","Biochemical and biophysical research communications","2017 Nov 4","Nimpong JA, Gebregziabher W, Singh UP, Nagarkatti P, Nagarkatti M, Hodge J, Liu C, Fan D, Ai W"
7253d8001
< "Q11131-1","27591321","Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene.","Journal of immunology (Baltimore, Md. : 1950)","2016 Oct 15","Pink M, Ratsch BA, Mardahl M, Durek P, Polansky JK, Karl M, Baumgrass R, Wallner S, Cadenas C, Gianmoena K, Floess S, Chen W, Nordstroem K, Tierling S, Olek S, Walter J, Hamann A, Syrbe U"
7254a8003
> "Q6P1D5-1","27716410","Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.","Molecular neurodegeneration","2016 Oct 5","Pigoni M, Wanngren J, Kuhn PH, Munro KM, Gunnersen JM, Takeshima H, Feederle R, Voytyuk I, De Strooper B, Levasseur MD, Hrupka BJ, Muller SA, Lichtenthaler SF"
7274,7277d8022
< "E9Q5C9-1","28493459","Enhanced NOLC1 promotes cell senescence and represses hepatocellular carcinoma cell proliferation by disturbing the organization of nucleolus.","Aging cell","2017 Aug","Yuan F, Zhang Y, Ma L, Cheng Q, Li G, Tong T"
< "E9Q5C9-1","26984997","Three-Dimensional Distribution of UBF and Nopp140 in Relationship to Ribosomal DNA Transcription During Mouse Preimplantation Development.","Biology of reproduction","2016 Apr","Kone MC, Fleurot R, Chebrout M, Debey P, Beaujean N, Bonnet-Garnier A"
< "Q80XG9-1","23911104","An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells.","Neuron","2013 Aug 21","Siddiqui TJ, Tari PK, Connor SA, Zhang P, Dobie FA, She K, Kawabe H, Wang YT, Brose N, Craig AM"
< "Q99P30-1","18799520","The nudix hydrolase 7 is an Acyl-CoA diphosphatase involved in regulating peroxisomal coenzyme A homeostasis.","Journal of biochemistry","2008 Nov","Reilly SJ, Tillander V, Ofman R, Alexson SE, Hunt MC"
7280,7282d8024
< "Q9R1X4-1","25448545","Morphological characterization of mammalian timeless in the mouse brain development.","Neuroscience research","2015 Mar","Inaguma Y, Ito H, Hara A, Iwamoto I, Matsumoto A, Yamagata T, Tabata H, Nagata K"
< "Q9R1X4-1","23266470","Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.","Cellular signalling","2013 Apr","O'Reilly LP, Zhang X, Smithgall TE"
< "Q9R1X4-1","23418588","Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.","PloS one","2013","Engelen E, Janssens RC, Yagita K, Smits VA, van der Horst GT, Tamanini F"
7287d8028
< "P97765-1","21642474","Tyrosine phosphorylation of transcriptional coactivator WW-domain binding protein 2 regulates estrogen receptor alpha function in breast cancer via the Wnt pathway.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2011 Sep","Lim SK, Orhant-Prioux M, Toy W, Tan KY, Lim YP"
7296,7297c8037
< "A2ALU4-1","21248203","Shroom2 regulates contractility to control endothelial morphogenesis.","Molecular biology of the cell","2011 Mar 15","Farber MJ, Rizaldy R, Hildebrand JD"
< "A2ALU4-1","17666436","Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.","Journal of cell science","2007 Aug 15","Etournay R, Zwaenepoel I, Perfettini I, Legrain P, Petit C, El-Amraoui A"
---
> "Q8VCH9-1","24692514","Activity-dependent genes in mouse olfactory sensory neurons.","Chemical senses","2014 Jun","Fischl AM, Heron PM, Stromberg AJ, McClintock TS"
7299,7305c8039,8040
< "Q9D411-1","26940607","Phosphorylated testis-specific serine/threonine kinase 4 may phosphorylate Crem at Ser-117.","Bioscience, biotechnology, and biochemistry","2016 Jun","Fu G, Wei Y, Wang X, Yu L"
< "Q9D411-1","26961893","Testis-specific serine/threonine protein kinase 4 (Tssk4) phosphorylates Odf2 at Ser-76.","Scientific reports","2016 Mar 10","Wang X, Li H, Fu G, Wang Y, Du S, Yu L, Wei Y, Chen S"
< "Q9D411-1","23599433","Heat shock protein 90 functions to stabilize and activate the testis-specific serine/threonine kinases, a family of kinases essential for male fertility.","The Journal of biological chemistry","2013 Jun 7","Jha KN, Coleman AR, Wong L, Salicioni AM, Howcroft E, Johnson GR"
< "Q9D411-1","23054012","Testis specific serine/threonine kinase 4 (Tssk4) maintains its kinase activity by phosphorylating itself at Thr-197.","Molecular biology reports","2013 Jan","Wei Y, Wang X, Fu G, Yu L"
< "Q3TZM9-1","25036826","Cloning and transcriptional expression of mouse mannosyltransferase IV/V cDNA, which is involved in the synthesis of lipid-linked oligosaccharides.","Bioscience, biotechnology, and biochemistry","2014","Nishimura Y, Shimono N, Yoshimoto T, Kamiguchi H, Nishikawa Y"
< "P30999-1","29875160","A role for proteolytic regulation of delta-catenin in remodeling a subpopulation of dendritic spines in the rodent brain.","The Journal of biological chemistry","2018 Jul 20","Yuan L, Singh D, Buescher JL, Arikkath J"
< "P30999-1","29130932","p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia.","The Journal of clinical investigation","2017 Dec 1","Short SP, Kondo J, Smalley-Freed WG, Takeda H, Dohn MR, Powell AE, Carnahan RH, Washington MK, Tripathi M, Payne DM, Jenkins NA, Copeland NG, Coffey RJ, Reynolds AB"
---
> "O08605-1","15234964","Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk.","The Journal of biological chemistry","2004 Sep 10","Orton KC, Ling J, Waskiewicz AJ, Cooper JA, Merrick WC, Korneeva NL, Rhoads RE, Sonenberg N, Traugh JA"
> "O08605-1","15254222","Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development.","Molecular and cellular biology","2004 Aug","Ueda T, Watanabe-Fukunaga R, Fukuyama H, Nagata S, Fukunaga R"
7310a8046
> "Q8CG46-1","28302748","SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.","Development (Cambridge, England)","2017 May 1","Hwang G, Sun F, O'Brien M, Eppig JJ, Handel MA, Jordan PW"
7311a8048,8050
> "Q8K019-1","29466738","Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b.","Cell reports","2018 Feb 20","Lowe M, Lage J, Paatela E, Munson D, Hostager R, Yuan C, Katoku-Kikyo N, Ruiz-Estevez M, Asakura Y, Staats J, Qahar M, Lohman M, Asakura A, Kikyo N"
> "Q8K019-1","28120329","Constitutive expression of the anti-apoptotic Bcl-2 family member A1 in murine endothelial cells leads to transplant tolerance.","Clinical and experimental immunology","2017 May","Smyth LA, Meader L, Xiao F, Woodward M, Brady HJ, Lechler R, Lombardi G"
> "Q8K019-1","24453340","Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2014 Jan 22","Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O"
7313,7314c8052,8056
< "O08759-1","30020076","UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity.","eLife","2018 Jul 18","Sun J, Liu Y, Jia Y, Hao X, Lin WJ, Tran J, Lynch G, Baudry M, Bi X"
< "O08759-1","12668607","Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a.","Human molecular genetics","2003 Apr 15","Yamasaki K, Joh K, Ohta T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Ogawa M, Wagstaff J, Kishino T"
---
> "Q9DBX2-1","29290584","CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.","Developmental cell","2018 Jan 8","Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R"
> "Q9DBX2-1","25659125","Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling.","PloS one","2015","Tracy CM, Kolesnikov AV, Blake DR, Chen CK, Baehr W, Kefalov VJ, Willardson BM"
> "Q9DBX2-1","23888055","Splice isoforms of phosducin-like protein control the expression of heterotrimeric G proteins.","The Journal of biological chemistry","2013 Sep 6","Gao X, Sinha S, Belcastro M, Woodard C, Ramamurthy V, Stoilov P, Sokolov M"
> "Q9DBX2-1","23637185","Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2013 May 1","Lai CW, Kolesnikov AV, Frederick JM, Blake DR, Jiang L, Stewart JS, Chen CK, Barrow JR, Baehr W, Kefalov VJ, Willardson BM"
> "Q9DBX2-1","15889144","Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly.","The EMBO journal","2005 Jun 1","Lukov GL, Hu T, McLaughlin JN, Hamm HE, Willardson BM"
7318a8061,8070
> "Q810L3-1","26566864","CHFR is important for the survival of male premeiotic germ cells.","Cell cycle (Georgetown, Tex.)","2015","Lu LY, Yu X"
> "Q810L3-1","22337872","CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.","The Journal of biological chemistry","2012 Apr 13","Kashima L, Idogawa M, Mita H, Shitashige M, Yamada T, Ogi K, Suzuki H, Toyota M, Ariga H, Sasaki Y, Tokino T"
> "Q810L3-1","22285184","SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components.","Biochemical and biophysical research communications","2012 Feb 17","Jung I, Sohn DH, Choi J, Kim JM, Jeon S, Seol JH, Seong RH"
> "Q810L3-1","21706008","Chfr and RNF8 synergistically regulate ATM activation.","Nature structural &amp; molecular biology","2011 Jun 26","Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X"
> "Q810L3-1","21245198","The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr.","Journal of cell science","2011 Feb 15","Castiel A, Danieli MM, David A, Moshkovitz S, Aplan PD, Kirsch IR, Brandeis M, Kramer A, Izraeli S"
> "Q810L3-1","19690386","Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.","The Journal of clinical investigation","2009 Sep","Fu Z, Regan K, Zhang L, Muders MH, Thibodeau SN, French A, Wu Y, Kaufmann SH, Lingle WL, Chen J, Tindall DJ"
> "Q810L3-1","15793587","Chfr is required for tumor suppression and Aurora A regulation.","Nature genetics","2005 Apr","Yu X, Minter-Dykhouse K, Malureanu L, Zhao WM, Zhang D, Merkle CJ, Ward IM, Saya H, Fang G, van Deursen J, Chen J"
> "Q810L3-1","15467728","PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein.","Nature structural &amp; molecular biology","2004 Nov","Daniels MJ, Marson A, Venkitaraman AR"
> "Q9ERZ3-1","28687610","Regulator of G-protein signaling Gbeta5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2017 Nov","Wang Q, Pronin AN, Levay K, Almaca J, Fornoni A, Caicedo A, Slepak VZ"
> "Q9DBA6-1","22002062","Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix.","The Journal of biological chemistry","2011 Dec 30","Okumoto K, Kametani Y, Fujiki Y"
7327a8080,8081
> "A2AMT1-1","29196765","Aquaporin 0 Modulates Lens Gap Junctions in the Presence of Lens-Specific Beaded Filament Proteins.","Investigative ophthalmology &amp; visual science","2017 Dec 1","Kumari S, Gao J, Mathias RT, Sun X, Eswaramoorthy A, Browne N, Zhang N, Varadaraj K"
> "A2AMT1-1","27559293","Expression of the type VI intermediate filament proteins CP49 and filensin in the mouse lens epithelium.","Molecular vision","2016","FitzGerald P, Sun N, Shibata B, Hess JF"
7355,7358c8109,8110
< "P49919-1","30284969","Cellular localization of the cell cycle inhibitor Cdkn1c controls growth arrest of adult skeletal muscle stem cells.","eLife","2018 Oct 4","Mademtzoglou D, Asakura Y, Borok MJ, Alonso-Martin S, Mourikis P, Kodaka Y, Mohan A, Asakura A, Relaix F"
< "P49919-1","17517131","Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.","BMC developmental biology","2007 May 21","Andrews SC, Wood MD, Tunster SJ, Barton SC, Surani MA, John RM"
< "Q9D9T6-1","27053129","Identification of host proteins, Spata3 and Dkk2, interacting with Toxoplasma gondii micronemal protein MIC3.","Parasitology research","2016 Jul","Wang Y, Fang R, Yuan Y, Pan M, Hu M, Zhou Y, Shen B, Zhao J"
< "Q9D9T6-1","18551385","Molecular cloning and characterization of a novel transcript variant of Mtsarg1 gene.","Molecular biology reports","2009 May","Li L, Liu G, Fu JJ, Li LY, Tan XJ, Yang S, Lu GX"
---
> "O88520-1","27466182","SHOC2 subcellular shuttling requires the KEKE motif-rich region and N-terminal leucine-rich repeat domain and impacts on ERK signalling.","Human molecular genetics","2016 Sep 1","Motta M, Chillemi G, Fodale V, Cecchetti S, Coppola S, Stipo S, Cordeddu V, Macioce P, Gelb BD, Tartaglia M"
> "O88520-1","16301319","Erbin inhibits RAF activation by disrupting the sur-8-Ras-Raf complex.","The Journal of biological chemistry","2006 Jan 13","Dai P, Xiong WC, Mei L"
7361d8112
< "Q9JHE7-1","10915772","Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.","Human molecular genetics","2000 Jul 22","Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J"
7368a8120,8121
> "Q60597-1","28242228","Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex.","Free radical biology &amp; medicine","2017 May","O'Brien M, Chalker J, Slade L, Gardiner D, Mailloux RJ"
> "Q60597-1","27582470","Oncometabolite d-2-hydroxyglutarate impairs alpha-ketoglutarate dehydrogenase and contractile function in rodent heart.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 13","Karlstaedt A, Zhang X, Vitrac H, Harmancey R, Vasquez H, Wang JH, Goodell MA, Taegtmeyer H"
7370a8124,8125
> "Q3V089-1","21364893","Identification and characterization of RBM44 as a novel intercellular bridge protein.","PloS one","2011 Feb 25","Iwamori T, Lin YN, Ma L, Iwamori N, Matzuk MM"
> "Q60865-1","14764709","Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins.","Journal of immunology (Baltimore, Md. : 1950)","2004 Feb 15","Grill B, Wilson GM, Zhang KX, Wang B, Doyonnas R, Quadroni M, Schrader JW"
7372d8126
< "Q7TMB8-1","14508708","Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.","American journal of human genetics","2003 Oct","Chai JH, Locke DP, Greally JM, Knoll JH, Ohta T, Dunai J, Yavor A, Eichler EE, Nicholls RD"
7385d8138
< "Q3V188-1","24344237","EndoU is a novel regulator of AICD during peripheral B cell selection.","The Journal of experimental medicine","2014 Jan 13","Poe JC, Kountikov EI, Lykken JM, Natarajan A, Marchuk DA, Tedder TF"
7389,7391c8142,8143
< "Q8BK03-1","28938432","Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.","Endocrinology","2017 Nov 1","Liu XM, Zhang YL, Ji SY, Zhao LW, Shang WN, Li D, Chen Z, Tong C, Fan HY"
< "Q8BK03-1","26716412","Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions.","Oncotarget","2016 Jan 12","Liu XM, Zhang YP, Ji SY, Li BT, Tian X, Li D, Tong C, Fan HY"
< "Q8BK03-1","26711011","Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.","Molecular cell","2016 Jan 7","Zhang Y, Liu X, Bai J, Tian X, Zhao X, Liu W, Duan X, Shang W, Fan HY, Tong C"
---
> "Q8K007-1","12368295","Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.","The Journal of biological chemistry","2002 Dec 20","Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S, Rosen SD"
> "P48615-1","30651543","Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback.","Nature communications","2019 Jan 16","Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D"
7392a8145
> "Q148B6-1","20542897","Speriolin is a novel human and mouse sperm centrosome protein.","Human reproduction (Oxford, England)","2010 Aug","Goto M, O'Brien DA, Eddy EM"
7393a8147
> "P51807-1","29094416","MAP6 interacts with Tctex1 and Cav 2.2/N-type calcium channels to regulate calcium signalling in neurons.","The European journal of neuroscience","2017 Dec","Brocard J, Dufour F, Gory-Faure S, Arnoult C, Bosc C, Denarier E, Peris L, Saoudi Y, De Waard M, Andrieux A"
7395a8150,8153
> "Q60855-1","30598363","RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.","Molecular cell","2019 Feb 7","Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schunke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P"
> "Q91VM3-1","26000824","The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis.","Autophagy","2015","Zhao YG, Sun L, Miao G, Ji C, Zhao H, Sun H, Miao L, Yoshii SR, Mizushima N, Wang X, Zhang H"
> "Q8K2Q9-1","26849555","CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization.","PloS one","2016","Nawaz MS, Giarda E, Bedogni F, La Montanara P, Ricciardi S, Ciceri D, Alberio T, Landsberger N, Rusconi L, Kilstrup-Nielsen C"
> "Q8K2Q9-1","23864681","Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2013 Jul 17","Sapir T, Levy T, Sakakibara A, Rabinkov A, Miyata T, Reiner O"
7397a8156
> "P08680-1","29958424","Anti-Correlation between the Dynamics of the Active Site Loop and C-Terminal Tail in Relation to the Homodimer Asymmetry of the Mouse Erythroid 5-Aminolevulinate Synthase.","International journal of molecular sciences","2018 Jun 28","Na I, Catena D, Kong MJ, Ferreira GC, Uversky VN"
7409a8169
> "A4Q9F1-1","23897886","Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia.","The Journal of cell biology","2013 Aug 5","Bosch Grau M, Gonzalez Curto G, Rocha C, Magiera MM, Marques Sousa P, Giordano T, Spassky N, Janke C"
7414,7418d8173
< "Q9Z2G9-1","25530119","TIP30 inhibits oligodendrocyte precursor cell differentiation via cytoplasmic sequestration of Olig1.","Glia","2015 Apr","Yang W, Xiao L, Li C, Liu X, Liu M, Shao Q, Wang D, Huang A, He C"
< "Q9Z2G9-1","25175814","Proteomic analysis of livers from fat-fed mice deficient in either PKCdelta or PKCepsilon identifies Htatip2 as a regulator of lipid metabolism.","Proteomics","2014 Nov","Liao BM, Raddatz K, Zhong L, Parker BL, Raftery MJ, Schmitz-Peiffer C"
< "Q9Z2G9-1","24853420","Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression.","Cell death &amp; disease","2014 May 22","Chen F, Li A, Gao S, Hollern D, Williams M, Liu F, VanSickle EA, Andrechek E, Zhang C, Yang C, Luo R, Xiao H"
< "Q9Z2G9-1","22733137","TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice.","Oncogene","2013 May 2","Li A, Zhang C, Gao S, Chen F, Yang C, Luo R, Xiao H"
< "Q9Z2G9-1","21252234","A novel TIP30 protein complex regulates EGF receptor signaling and endocytic degradation.","The Journal of biological chemistry","2011 Mar 18","Zhang C, Li A, Zhang X, Xiao H"
7422a8178,8181
> "Q9ES97-1","28238655","RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3.","Current biology : CB","2017 Mar 6","Bastide A, Peretti D, Knight JR, Grosso S, Spriggs RV, Pichon X, Sbarrato T, Roobol A, Roobol J, Vito D, Bushell M, von der Haar T, Smales CM, Mallucci GR, Willis AE"
> "Q9ES97-1","15946766","Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain.","Brain research. Molecular brain research","2005 Aug 18","Cai Y, Saiyin H, Lin Q, Zhang P, Tang L, Pan X, Yu L"
> "Q9ES97-1","15350194","Tissue specificity and regulation of the N-terminal diversity of reticulon 3.","The Biochemical journal","2005 Jan 1","Di Scala F, Dupuis L, Gaiddon C, De Tapia M, Jokic N, Gonzalez de Aguilar JL, Raul JS, Ludes B, Loeffler JP"
> "Q9ES97-1","11990451","Molecular cloning and characterization of the mouse reticulon 3 cDNA.","Cellular and molecular biology (Noisy-le-Grand, France)","2002 Mar","Hamada N, Iwahashi J, Suzuki K, Ogi H, Kashiwagi T, Hara K, Toyoda M, Yamada T, Toyoda T"
7427a8187
> "P49452-1","22540025","CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.","Nucleus (Austin, Tex.)","2012 Jan-Feb","Dambacher S, Deng W, Hahn M, Sadic D, Frohlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G"
7429,7432c8189,8191
< "Q8VEL0-1","21792907","Mospd1, a new player in mesenchymal versus epidermal cell differentiation.","Journal of cellular physiology","2011 Oct","Thaler R, Rumpler M, Spitzer S, Klaushofer K, Varga F"
< "Q8K019-1","29466738","Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b.","Cell reports","2018 Feb 20","Lowe M, Lage J, Paatela E, Munson D, Hostager R, Yuan C, Katoku-Kikyo N, Ruiz-Estevez M, Asakura Y, Staats J, Qahar M, Lohman M, Asakura A, Kikyo N"
< "Q8K019-1","28120329","Constitutive expression of the anti-apoptotic Bcl-2 family member A1 in murine endothelial cells leads to transplant tolerance.","Clinical and experimental immunology","2017 May","Smyth LA, Meader L, Xiao F, Woodward M, Brady HJ, Lechler R, Lombardi G"
< "Q8K019-1","24453340","Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2014 Jan 22","Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O"
---
> "Q8BG87-1","30979904","TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn.","Nature communications","2019 Apr 12","Montalban-Loro R, Lozano-Urena A, Ito M, Krueger C, Reik W, Ferguson-Smith AC, Ferron SR"
> "Q8BG87-1","30575719","A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset.","Nature communications","2018 Dec 21","Selimoglu-Buet D, Riviere J, Ghamlouch H, Bencheikh L, Lacout C, Morabito M, Diop M, Meurice G, Breckler M, Chauveau A, Debord C, Debeurme F, Itzykson R, Chapuis N, Willekens C, Wagner-Ballon O, Bernard OA, Droin N, Solary E"
> "Q8BG87-1","20639862","Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.","Nature","2010 Aug 26","Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y"
7439a8199,8201
> "Q91XW8-1","22902560","A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.","Molecular cell","2012 Sep 28","Xiol J, Cora E, Koglgruber R, Chuma S, Subramanian S, Hosokawa M, Reuter M, Yang Z, Berninger P, Palencia A, Benes V, Penninger J, Sachidanandam R, Pillai RS"
> "Q91XW8-1","18408354","Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency.","The Journal of reproduction and development","2008 Jun","Noguchi J, Ozawa M, Nakai M, Somfai T, Kikuchi K, Kaneko H, Kunieda T"
> "Q91XW8-1","12764197","Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.","Science (New York, N.Y.)","2003 May 23","Crackower MA, Kolas NK, Noguchi J, Sarao R, Kikuchi K, Kaneko H, Kobayashi E, Kawai Y, Kozieradzki I, Landers R, Mo R, Hui CC, Nieves E, Cohen PE, Osborne LR, Wada T, Kunieda T, Moens PB, Penninger JM"
7442a8205,8206
> "Q69ZK9-1","15540461","Neuroligin 2 is exclusively localized to inhibitory synapses.","European journal of cell biology","2004 Sep","Varoqueaux F, Jamain S, Brose N"
> "Q9QXA1-1","29609111","Regulation of anxiety-like behavior and Crhr1 expression in the basolateral amygdala by LMO3.","Psychoneuroendocrinology","2018 Jun","Savarese A, Lasek AW"
7444,7447d8207
< "P70704-1","27287255","Aberrant hippocampal Atp8a1 levels are associated with altered synaptic strength, electrical activity, and autistic-like behavior.","Biochimica et biophysica acta","2016 Sep","Kerr DJ, Marsillo A, Guariglia SR, Budylin T, Sadek R, Menkes S, Chauhan A, Wen GY, McCloskey DP, Wieraszko A, Banerjee P"
< "P70704-1","22007859","Atp8a1 deficiency is associated with phosphatidylserine externalization in hippocampus and delayed hippocampus-dependent learning.","Journal of neurochemistry","2012 Jan","Levano K, Punia V, Raghunath M, Debata PR, Curcio GM, Mogha A, Purkayastha S, McCloskey D, Fata J, Banerjee P"
< "P70704-1","17239457","Isolation, sequencing, and functional analysis of the TATA-less murine ATPase II promoter and structural analysis of the ATPase II gene.","Biochimica et biophysica acta","2007 Jan","Sobocki T, Jayman F, Sobocka MB, Marmur JD, Banerjee P"
< "P70704-1","14975727","A novel aminophospholipid transporter exclusively expressed in spermatozoa is required for membrane lipid asymmetry and normal fertilization.","Developmental biology","2004 Mar 1","Wang L, Beserra C, Garbers DL"
7455a8216
> "Q8BKE9-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
7459a8221,8224
> "Q99JY0-1","25816318","Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid beta-oxidation.","PLoS pathogens","2015 Mar","Kao YT, Chang BL, Liang JJ, Tsai HJ, Lee YL, Lin RJ, Lin YL"
> "Q501J6-1","29431742","Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA.","Nature medicine","2018 Mar","Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P"
> "Q501J6-1","26947125","The loop structure and the RNA helicase p72/DDX17 influence the processing efficiency of the mice miR-132.","Scientific reports","2016 Mar 7","Remenyi J, Bajan S, Fuller-Pace FV, Arthur JS, Hutvagner G"
> "Q501J6-1","22266867","Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.","Oncogene","2012 Oct 18","Germann S, Gratadou L, Zonta E, Dardenne E, Gaudineau B, Fougere M, Samaan S, Dutertre M, Jauliac S, Auboeuf D"
7463d8227
< "Q3URQ7-1","26525917","MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.","Brain : a journal of neurology","2016 Jan","MacNair L, Xiao S, Miletic D, Ghani M, Julien JP, Keith J, Zinman L, Rogaeva E, Robertson J"
7474,7475d8237
< "P42682-1","26466958","A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.","Journal of immunology (Baltimore, Md. : 1950)","2015 Nov 15","Cho HS, Shin HM, Haberstock-Debic H, Xing Y, Owens TD, Funk JO, Hill RJ, Bradshaw JM, Berg LJ"
< "P42682-1","22403441","A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice.","Journal of immunology (Baltimore, Md. : 1950)","2012 Apr 15","Qi Q, Huang W, Bai Y, Balmus G, Weiss RS, August A"
7478,7481c8240,8241
< "Q62219-1","29242607","The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.","Oncogene","2018 Mar","Omoto T, Kim-Kaneyama JR, Lei XF, Orimo A, Ohnishi K, Yoshihara K, Miyauchi A, Li S, Gao L, Umemoto T, Tanaka J, Nakahara K, Takeya M, Ishida F, Kudo SE, Haraguchi S, Miyazaki T, Miyazaki A"
< "Q62219-1","27893716","Hic-5 remodeling of the stromal matrix promotes breast tumor progression.","Oncogene","2017 May 11","Goreczny GJ, Ouderkirk-Pecone JL, Olson EC, Krendel M, Turner CE"
< "Q62219-1","28139974","The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 alpha-enhancer activity.","eLife","2017 Jan 31","Kim Y, Lim S, Ha T, Song YH, Sohn YI, Park DJ, Paik SS, Kim-Kaneyama JR, Song MR, Leung A, Levine EM, Kim IB, Goo YS, Lee SH, Kang KH, Kim JW"
< "Q62219-1","27269065","Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.","The Journal of cell biology","2016 Jun 6","Petropoulos C, Oddou C, Emadali A, Hiriart-Bryant E, Boyault C, Faurobert E, Vande Pol S, Kim-Kaneyama JR, Kraut A, Coute Y, Block M, Albiges-Rizo C, Destaing O"
---
> "Q80ZD8-1","26240432","AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.","Schizophrenia bulletin","2016 Jan","Peltola MA, Kuja-Panula J, Liuhanen J, Voikar V, Piepponen P, Hiekkalinna T, Taira T, Lauri SE, Suvisaari J, Kulesskaya N, Paunio T, Rauvala H"
> "Q80ZD8-1","22056818","AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.","EMBO reports","2011 Dec 1","Peltola MA, Kuja-Panula J, Lauri SE, Taira T, Rauvala H"
7484,7487c8244,8245
< "O70293-1","30576947","Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and beta-arrestin 2 in inflammatory macrophages.","Molecular immunology","2019 Feb","Serafin DS, Allyn B, Sassano MF, Timoshchenko RG, Mattox D, Brozowski JM, Siderovski DP, Truong YK, Esserman D, Tarrant TK, Billard MJ"
< "O70293-1","28939643","Role of G protein-coupled receptor kinase-6 in Escherichia coli lung infection model in mice.","Physiological genomics","2017 Nov 1","Lee T, Packiriswamy N, Lee E, Lucas PC, McCabe LR, Parameswaran N"
< "O70293-1","28457871","Dendritic Cells Interpret Haptotactic Chemokine Gradients in a Manner Governed by Signal-to-Noise Ratio and Dependent on GRK6.","Current biology : CB","2017 May 8","Schwarz J, Bierbaum V, Vaahtomeri K, Hauschild R, Brown M, de Vries I, Leithner A, Reversat A, Merrin J, Tarrant T, Bollenbach T, Sixt M"
< "O70293-1","12032308","Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.","Proceedings of the National Academy of Sciences of the United States of America","2002 May 28","Fong AM, Premont RT, Richardson RM, Yu YR, Lefkowitz RJ, Patel DD"
---
> "Q9QXS6-1","30700723","ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans.","Nature communications","2019 Jan 30","Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ"
> "Q9QXS6-1","12761245","Cell biological and biochemical characterization of drebrin complexes in mesangial cells and podocytes of renal glomeruli.","Journal of the American Society of Nephrology : JASN","2003 Jun","Peitsch WK, Hofmann I, Endlich N, Pratzel S, Kuhn C, Spring H, Grone HJ, Kriz W, Franke WW"
7491a8250,8252
> "Q58FA4-1","29329320","Atypical E2f functions are critical for pancreas polyploidization.","PloS one","2018","Matondo RB, Moreno E, Toussaint MJM, Tooten PCJ, van Essen SC, van Liere EA, Youssef SA, Bongiovanni L, de Bruin A"
> "Q58FA4-1","15722552","Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.","The Journal of biological chemistry","2005 May 6","Maiti B, Li J, de Bruin A, Gordon F, Timmers C, Opavsky R, Patil K, Tuttle J, Cleghorn W, Leone G"
> "P40645-1","17433257","Identification and characterization of the human SOX6 promoter.","Biochemical and biophysical research communications","2007 Jun 1","Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI"
7508,7510d8268
< "Q9ESU6-1","29662175","Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.","Nature cell biology","2018 May","Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB"
< "Q9ESU6-1","12192049","A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase.","Molecular and cellular biology","2002 Sep","Maruyama T, Farina A, Dey A, Cheong J, Bermudez VP, Tamura T, Sciortino S, Shuman J, Hurwitz J, Ozato K"
< "Q9ESU6-1","11997514","Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.","Molecular and cellular biology","2002 Jun","Houzelstein D, Bullock SL, Lynch DE, Grigorieva EF, Wilson VA, Beddington RS"
7514a8273
> "Q9DBY1-1","29916549","The NRF2PGC1beta pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, synoviolin, in a cecal ligation/perforationinduced septic mouse model.","Molecular medicine reports","2018 Aug","Ishida Y, Fujita H, Aratani S, Chijiiwa M, Taniguchi N, Yokota M, Ogihara Y, Uoshima N, Nagashima F, Uchino H, Nakajima T"
7521a8281,8285
> "Q8BKD6-1","20615966","Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.","Proceedings of the National Academy of Sciences of the United States of America","2010 Jul 20","Sayan BS, Yang AL, Conforti F, Tucci P, Piro MC, Browne GJ, Agostini M, Bernardini S, Knight RA, Mak TW, Melino G"
> "Q07475-1","27927130","P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation.","Stem cells and development","2017 Mar 15","Yao Z, Li H, He W, Yang S, Zhang X, Zhan R, Xu R, Tan J, Zhou J, Wu J, Luo G"
> "Q07475-1","27939132","Neuronal Protein 3.1 Deficiency Leads to Reduced Cutaneous Scar Collagen Deposition and Tensile Strength due to Impaired Transforming Growth Factor-beta1 to -beta3 Translation.","The American journal of pathology","2017 Feb","Cheng T, Yue M, Aslam MN, Wang X, Shekhawat G, Varani J, Schuger L"
> "Q07475-1","27906099","P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor beta1 expression.","Stem cell research &amp; therapy","2016 Dec 1","Li H, Yao Z, He W, Gao H, Bai Y, Yang S, Zhang L, Zhan R, Tan J, Zhou J, Takata M, Wu J, Luo G"
> "Q07475-1","12417574","P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype.","The Journal of clinical investigation","2002 Nov","Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L"
7529a8294,8296
> "Q14AX6-1","27073218","Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.","Cerebral cortex (New York, N.Y. : 1991)","2017 Mar 1","Chen HR, Juan HC, Wong YH, Tsai JW, Fann MJ"
> "Q14AX6-1","26658019","Cdk12 is essential for embryonic development and the maintenance of genomic stability.","Cell death and differentiation","2016 Jun","Juan HC, Lin Y, Chen HR, Fann MJ"
> "Q14AX6-1","24999027","Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.","Experimental neurology","2014 Nov","Chen HR, Lin GT, Huang CK, Fann MJ"
7535c8302,8304
< "P70188-1","16298999","Role of the kinesin-2 family protein, KIF3, during mitosis.","The Journal of biological chemistry","2006 Feb 17","Haraguchi K, Hayashi T, Jimbo T, Yamamoto T, Akiyama T"
---
> "Q8CHD8-1","24576489","Endosomal localization of FIP3/Arfophilin-1 and its involvement in dendritic formation of mouse hippocampal neurons.","Brain research","2014 Apr 4","Yazaki Y, Hara Y, Tamaki H, Fukaya M, Sakagami H"
> "Q8CHD8-1","20736163","A novel cytoplasmic adaptor for retinoic acid receptor (RAR) and thyroid receptor functions as a Derepressor of RAR in the absence of retinoic acid.","The Journal of biological chemistry","2010 Oct 29","Park UH, Kim EJ, Um SJ"
> "Q8CHD8-1","15601896","The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.","Molecular biology of the cell","2005 Feb","Wilson GM, Fielding AB, Simon GC, Yu X, Andrews PD, Hames RS, Frey AM, Peden AA, Gould GW, Prekeris R"
7539,7542d8307
< "O09012-1","26086376","Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts.","Autophagy","2015","Nordgren M, Francisco T, Lismont C, Hennebel L, Brees C, Wang B, Van Veldhoven PP, Azevedo JE, Fransen M"
< "O09012-1","22458306","Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system.","Journal of neuroinflammation","2012 Mar 29","Bottelbergs A, Verheijden S, Van Veldhoven PP, Just W, Devos R, Baes M"
< "P47757-1","20969875","The interaction of capping protein with the barbed end of the actin filament.","Journal of molecular biology","2010 Dec 17","Kim T, Cooper JA, Sept D"
< "P47757-1","19806181","Capzb2 interacts with beta-tubulin to regulate growth cone morphology and neurite outgrowth.","PLoS biology","2009 Oct","Davis DA, Wilson MH, Giraud J, Xie Z, Tseng HC, England C, Herscovitz H, Tsai LH, Delalle I"
7545a8311,8312
> "P97447-1","30260394","Cardiomyopathy and altered integrin-actin signaling in Fhl1 mutant female mice.","Human molecular genetics","2019 Jan 15","Kubota A, Juanola-Falgarona M, Emmanuele V, Sanchez-Quintero MJ, Kariya S, Sera F, Homma S, Tanji K, Quinzii CM, Hirano M"
> "Q8BMK0-1","26220856","Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction.","Journal of cell science","2015 Sep 1","Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, Yu X"
7556d8322
< "Q8CDP0-1","25103237","The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.","Molecular biology of the cell","2014 Oct 1","Tort O, Tanco S, Rocha C, Bieche I, Seixas C, Bosc C, Andrieux A, Moutin MJ, Aviles FX, Lorenzo J, Janke C"
7563,7566c8329
< "Q920R0-1","27439389","Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.","Human molecular genetics","2016 Aug 1","Hadano S, Mitsui S, Pan L, Otomo A, Kubo M, Sato K, Ono S, Onodera W, Abe K, Chen X, Koike M, Uchiyama Y, Aoki M, Warabi E, Yamamoto M, Ishii T, Yanagawa T, Shang HF, Yoshii F"
< "Q920R0-1","26755825","Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms.","Human molecular genetics","2016 Mar 15","Gautam M, Jara JH, Sekerkova G, Yasvoina MV, Martina M, Ozdinler PH"
< "Q920R0-1","22982304","Are alsin and spartin novel interaction partners?","Biochemical and biophysical research communications","2012 Oct 12","Cobanoglu G, Ozansoy M, Basak AN"
< "Q920R0-1","21937428","Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity.","The Journal of biological chemistry","2011 Nov 18","Li Q, Spencer NY, Pantazis NJ, Engelhardt JF"
---
> "P21836-1","30076217","Microphthalmia-associated transcription factor up-regulates acetylcholinesterase expression during melanogenesis of murine melanoma cells.","The Journal of biological chemistry","2018 Sep 14","Wu Q, Fung AHY, Xu ML, Poon K, Liu EYL, Kong XP, Yao P, Xiong QP, Dong TTX, Tsim KWK"
7567a8331,8336
> "Q3UJD6-1","29901692","Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling.","Endocrinology","2018 Aug 1","Coyne ES, Bedard N, Wykes L, Stretch C, Jammoul S, Li S, Zhang K, Sladek RS, Bathe OF, Jagoe RT, Posner BI, Wing SS"
> "Q3UJD6-1","28886438","Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor beta and increases skeletal muscle mass in young female mice.","The Journal of nutritional biochemistry","2017 Nov","Ogawa M, Kitano T, Kawata N, Sugihira T, Kitakaze T, Harada N, Yamaji R"
> "Q3UJD6-1","26048142","Inactivation of the ubiquitin-specific protease 19 deubiquitinating enzyme protects against muscle wasting.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2015 Sep","Bedard N, Jammoul S, Moore T, Wykes L, Hallauer PL, Hastings KE, Stretch C, Baracos V, Chevalier S, Plourde M, Coyne E, Wing SS"
> "Q3UJD6-1","25568336","USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling.","Molecular biology of the cell","2015 Mar 1","Wiles B, Miao M, Coyne E, Larose L, Cybulsky AV, Wing SS"
> "Q3UJD6-1","21971047","17beta-estradiol represses myogenic differentiation by increasing ubiquitin-specific peptidase 19 through estrogen receptor alpha.","The Journal of biological chemistry","2011 Dec 2","Ogawa M, Yamaji R, Higashimura Y, Harada N, Ashida H, Nakano Y, Inui H"
> "Q3UJD6-1","19015242","USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.","Molecular and cellular biology","2009 Jan","Lu Y, Adegoke OA, Nepveu A, Nakayama KI, Bedard N, Cheng D, Peng J, Wing SS"
7584,7590c8353,8354
< "Q9WVG6-1","30391528","Dorsal Root Ganglia Coactivator-associated Arginine Methyltransferase 1 Contributes to Peripheral Nerve Injury-induced Pain Hypersensitivities.","Neuroscience","2018 Dec 1","Mo K, Xu H, Gong H, Lei H, Wang Y, Guo W, Xu S, Tu W"
< "Q9WVG6-1","30366907","A C9orf72-CARM1 axis regulates lipid metabolism under glucose starvation-induced nutrient stress.","Genes &amp; development","2018 Nov 1","Liu Y, Wang T, Ji YJ, Johnson K, Liu H, Johnson K, Bailey S, Suk Y, Lu YN, Liu M, Wang J"
< "Q61142-1","23894536","A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption.","PloS one","2013","Chew TG, Peaston A, Lim AK, Lorthongpanich C, Knowles BB, Solter D"
< "Q61142-1","21960006","Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes.","EMBO reports","2011 Oct 28","Wang W, Chen Z, Mao Z, Zhang H, Ding X, Chen S, Zhang X, Xu R, Zhu B"
< "Q61142-1","18645677","Characterization of Spindlin1 isoform2 in mouse testis.","Asian journal of andrology","2008 Sep","Zhang KM, Wang YF, Huo R, Bi Y, Lin M, Sha JH, Zhou ZM"
< "Q61142-1","18201843","Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis.","Gene","2008 Feb 29","Yuan H, Zhang P, Qin L, Chen L, Shi S, Lu Y, Yan F, Bai C, Nan X, Liu D, Li Y, Yue W, Pei X"
< "Q61142-1","16098913","Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells.","Biochemical and biophysical research communications","2005 Sep 23","Gao Y, Yue W, Zhang P, Li L, Xie X, Yuan H, Chen L, Liu D, Yan F, Pei X"
---
> "Q8CGA3-1","15659399","Identification of LAT4, a novel amino acid transporter with system L activity.","The Journal of biological chemistry","2005 Mar 25","Bodoy S, Martin L, Zorzano A, Palacin M, Estevez R, Bertran J"
> "P26048-1","30087324","Developmental seizures and mortality result from reducing GABAA receptor alpha2-subunit interaction with collybistin.","Nature communications","2018 Aug 7","Hines RM, Maric HM, Hines DJ, Modgil A, Panzanelli P, Nakamura Y, Nathanson AJ, Cross A, Deeb T, Brandon NJ, Davies P, Fritschy JM, Schindelin H, Moss SJ"
7604a8369
> "Q8K402-1","12374769","Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patients.","Human molecular genetics","2002 Oct 15","Braybrook C, Lisgo S, Doudney K, Henderson D, Marcano AC, Strachan T, Patton MA, Villard L, Moore GE, Stanier P, Lindsay S"
7608a8374
> "O55176-3","28067271","Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38alpha activation.","Nature communications","2017 Jan 9","Consalvi S, Brancaccio A, Dall'Agnese A, Puri PL, Palacios D"
7620,7624d8385
< "Q8CBR1-1","28461473","ILDR1 is important for paracellular water transport and urine concentration mechanism.","Proceedings of the National Academy of Sciences of the United States of America","2017 May 16","Gong Y, Himmerkus N, Sunq A, Milatz S, Merkel C, Bleich M, Hou J"
< "Q8CBR1-1","25822906","Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.","PloS one","2015","Higashi T, Katsuno T, Kitajiri S, Furuse M"
< "Q8CBR1-1","25217574","ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.","Human molecular genetics","2015 Feb 1","Morozko EL, Nishio A, Ingham NJ, Chandra R, Fitzgerald T, Martelletti E, Borck G, Wilson E, Riordan GP, Wangemann P, Forge A, Steel KP, Liddle RA, Friedman TB, Belyantseva IA"
< "Q8CBR1-1","23863714","Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion.","The Journal of clinical investigation","2013 Aug","Chandra R, Wang Y, Shahid RA, Vigna SR, Freedman NJ, Liddle RA"
< "Q8CBR1-1","23239027","Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.","Journal of cell science","2013 Feb 15","Higashi T, Tokuda S, Kitajiri S, Masuda S, Nakamura H, Oda Y, Furuse M"
7634a8396
> "P43404-1","29980684","Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.","Nature communications","2018 Jul 6","Zhao M, Svensson MND, Venken K, Chawla A, Liang S, Engel I, Mydel P, Day J, Elewaut D, Bottini N, Kronenberg M"
7636,7637d8397
< "Q8CC88-1","29660410","The spatial and developmental expression of mouse Vwa8 (von Willebrand domain-containing protein 8).","Gene expression patterns : GEP","2018 Sep","Grewe BS, Richmond JE, Featherstone DE"
< "Q8CC88-1","28414126","Characterization of the novel protein KIAA0564 (Von Willebrand Domain-containing Protein 8).","Biochemical and biophysical research communications","2017 Jun 3","Luo M, Mengos AE, Ma W, Finlayson J, Bustos RZ, Xiao Zhu Y, Shi CX, Stubblefield TM, Willis WT, Mandarino LJ"
7642a8403
> "Q8CFG0-1","12368295","Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.","The Journal of biological chemistry","2002 Dec 20","Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S, Rosen SD"
7644a8406,8410
> "Q922U1-1","25111227","Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.","The American journal of pathology","2014 Oct","Farkas MH, Lew DS, Sousa ME, Bujakowska K, Chatagnon J, Bhattacharya SS, Pierce EA, Nandrot EF"
> "Q922U1-1","21283520","Temporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP.","PloS one","2011 Jan 19","Cao H, Wu J, Lam S, Duan R, Newnham C, Molday RS, Graziotto JJ, Pierce EA, Hu J"
> "Q922U1-1","20811066","Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.","Investigative ophthalmology &amp; visual science","2011 Jan","Graziotto JJ, Farkas MH, Bujakowska K, Deramaudt BM, Zhang Q, Nandrot EF, Inglehearn CF, Bhattacharya SS, Pierce EA"
> "Q922U1-1","18395097","EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.","Gastroenterology","2008 Apr","Niehof M, Borlak J"
> "Q8BKC8-1","23541637","Aldosterone-induced ENaC and basal Na+/K+-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIIIbeta trans Golgi signalling in M1 cortical collecting duct cells.","Molecular and cellular endocrinology","2013 Jun 15","Dooley R, Angibaud E, Yusef YR, Thomas W, Harvey BJ"
7649d8414
< "Q9QZS3-1","14641329","Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas.","Differentiation; research in biological diversity","2003 Oct","Yoshida T, Tokunaga A, Nakao K, Okano H"
7655a8421
> "Q8BFY0-1","29724821","Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels.","The Journal of biological chemistry","2018 Jun 15","Hilton JK, Salehpour T, Sisco NJ, Rath P, Van Horn WD"
7659a8426
> "Q3UEI1-1","21670265","Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.","Proceedings of the National Academy of Sciences of the United States of America","2011 Jun 28","Choi YH, Suzuki A, Hajarnis S, Ma Z, Chapin HC, Caplan MJ, Pontoglio M, Somlo S, Igarashi P"
7662,7664d8428
< "Q3UMR0-1","27066885","A Varp-Binding Protein, RACK1, Regulates Dendrite Outgrowth through Stabilization of Varp Protein in Mouse Melanocytes.","The Journal of investigative dermatology","2016 Aug","Marubashi S, Ohbayashi N, Fukuda M"
< "Q3UMR0-1","19403694","Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes.","Molecular biology of the cell","2009 Jun","Tamura K, Ohbayashi N, Maruta Y, Kanno E, Itoh T, Fukuda M"
< "Q3UMR0-1","16525121","Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics.","Journal of cell science","2006 Mar 15","Zhang X, He X, Fu XY, Chang Z"
7665a8430
> "Q8C7J6-1","21452234","Distribution of the auxiliary GABAB receptor subunits KCTD8, 12, 12b, and 16 in the mouse brain.","The Journal of comparative neurology","2011 Jun 1","Metz M, Gassmann M, Fakler B, Schaeren-Wiemers N, Bettler B"
7671a8437,8438
> "Q80XC2-1","16043508","The bipartite structure of the tRNA m1A58 methyltransferase from S. cerevisiae is conserved in humans.","RNA (New York, N.Y.)","2005 Aug","Ozanick S, Krecic A, Andersland J, Anderson JT"
> "Q91X17-1","18375198","Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage.","Biochemical and biophysical research communications","2008 Jun 6","Santambrogio S, Cattaneo A, Bernascone I, Schwend T, Jovine L, Bachi A, Rampoldi L"
7674a8442,8443
> "Q8BVA5-1","30169630","Loss of LDAH associated with prostate cancer and hearing loss.","Human molecular genetics","2018 Dec 15","Currall BB, Chen M, Sallari RC, Cotter M, Wong KE, Robertson NG, Penney KL, Lunardi A, Reschke M, Hickox AE, Yin Y, Wong GT, Fung J, Brown KK, Williamson RE, Sinnott-Armstrong NA, Kammin T, Ivanov A, Zepeda-Mendoza CJ, Shen J, Quade BJ, Signoretti S, Arnos KS, Banks AS, Patsopoulos N, Liberman MC, Kellis M, Pandolfi PP, Morton CC"
> "Q8BVA5-1","24357060","Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization.","Arteriosclerosis, thrombosis, and vascular biology","2014 Feb","Goo YH, Son SH, Kreienberg PB, Paul A"
7679,7681d8447
< "O35136-1","26611261","Abeta-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.","Nature communications","2015 Nov 27","Leshchyns'ka I, Liew HT, Shepherd C, Halliday GM, Stevens CH, Ke YD, Ittner LM, Sytnyk V"
< "O35136-1","25875008","OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor.","PloS one","2015","Deleyrolle L, Sabourin JC, Rothhut B, Fujita H, Guichet PO, Teigell M, Ripoll C, Chauvet N, Perrin F, Mamaeva D, Noda T, Mori K, Yoshihara Y, Hugnot JP"
< "O35136-1","25632147","Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Jan 28","Sheng L, Leshchyns'ka I, Sytnyk V"
7685a8452,8459
> "Q7JJ13-1","28388437","The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.","Molecular cell","2017 Apr 6","Hsu SC, Gilgenast TG, Bartman CR, Edwards CR, Stonestrom AJ, Huang P, Emerson DJ, Evans P, Werner MT, Keller CA, Giardine B, Hardison RC, Raj A, Phillips-Cremins JE, Blobel GA"
> "Q7JJ13-1","28262505","Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.","Molecular cell","2017 Mar 16","Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM"
> "Q7JJ13-1","27865874","Bromodomain-containing protein 2 induces insulin resistance via the mTOR/Akt signaling pathway and an inflammatory response in adipose tissue.","Cellular signalling","2017 Jan","Sun R, Wu Y, Hou W, Sun Z, Wang Y, Wei H, Mo W, Yu M"
> "Q7JJ13-1","26804911","H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs.","Cell reports","2016 Feb 9","Surface LE, Fields PA, Subramanian V, Behmer R, Udeshi N, Peach SE, Carr SA, Jaffe JD, Boyer LA"
> "Q7JJ13-1","9528865","Stimulation of p85/RING3 kinase in multiple organs after systemic administration of mitogens into mice.","Oncogene","1998 Mar 5","Ostrowski J, Florio SK, Denis GV, Suzuki H, Bomsztyk K"
> "Q1ERP8-1","24376728","Dynamic changes in endothelial cell adhesion molecule nepmucin/CD300LG expression under physiological and pathological conditions.","PloS one","2013","Umemoto E, Takeda A, Jin S, Luo Z, Nakahogi N, Hayasaka H, Lee CM, Tanaka T, Miyasaka M"
> "Q1ERP8-1","18675811","Nepmucin/CLM-9, an Ig domain-containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration in vitro.","FEBS letters","2008 Sep 3","Jin S, Umemoto E, Tanaka T, Shimomura Y, Tohya K, Kunizawa K, Yang BG, Jang MH, Hirata T, Miyasaka M"
> "Q1ERP8-1","16754720","Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow.","The Journal of experimental medicine","2006 Jun 12","Umemoto E, Tanaka T, Kanda H, Jin S, Tohya K, Otani K, Matsutani T, Matsumoto M, Ebisuno Y, Jang MH, Fukuda M, Hirata T, Miyasaka M"
7687a8462,8465
> "Q9R0U0-1","26586428","SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.","Cell reports","2015 Nov 24","Wei N, Cheng Y, Wang Z, Liu Y, Luo C, Liu L, Chen L, Xie Z, Lu Y, Feng Y"
> "Q9R0U0-1","25627895","Splicing factor NSSR1 reduces neuronal injury after mouse transient global cerebral ischemia.","Glia","2015 May","Qi Y, Li Y, Cui SC, Zhao JJ, Liu XY, Ji CX, Sun FY, Xu P, Chen XH"
> "Q9R0U0-1","24710272","SRSF10 regulates alternative splicing and is required for adipocyte differentiation.","Molecular and cellular biology","2014 Jun","Li H, Cheng Y, Wu W, Liu Y, Wei N, Feng X, Xie Z, Feng Y"
> "Q9R0U0-1","24668663","Dephosphorylation of NSSR1 regulates alternative splicing of the GluR-B minigene.","Genetics and molecular research : GMR","2014 Mar 17","Zhang W, Li LL, Chen XH, Peng ZY"
7689,7693c8467
< "Q8C6P8-1","28476430","Imprinted control regions include composite DNA elements consisting of the ZFP57 binding site overlapping MLL1 morphemes.","Genomics","2017 Jul","Bina M"
< "Q8C6P8-1","27257070","ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells.","Nucleic acids research","2016 Sep 30","Riso V, Cammisa M, Kukreja H, Anvar Z, Verde G, Sparago A, Acurzio B, Lad S, Lonardo E, Sankar A, Helin K, Feil R, Fico A, Angelini C, Grimaldi G, Riccio A"
< "Q8C6P8-1","26481358","ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells.","Nucleic acids research","2016 Feb 18","Anvar Z, Cammisa M, Riso V, Baglivo I, Kukreja H, Sparago A, Girardot M, Lad S, De Feis I, Cerrato F, Angelini C, Feil R, Pedone PV, Grimaldi G, Riccio A"
< "Q8C6P8-1","26025256","Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.","Genome biology","2015 May 30","Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC"
< "Q8C6P8-1","18854139","A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.","Developmental cell","2008 Oct","Li X, Ito M, Zhou F, Youngson N, Zuo X, Leder P, Ferguson-Smith AC"
---
> "O35484-1","19997757","Developmental alterations in expression and subcellular localization of antizyme and antizyme inhibitor and their functional importance in the murine mammary gland.","Amino acids","2010 Feb","Murakami Y, Suzuki J, Samejima K, Oka T"
7697,7699c8471,8473
< "P55292-1","30115995","Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury.","Mucosal immunology","2018 Nov","Gross A, Pack LAP, Schacht GM, Kant S, Ungewiss H, Meir M, Schlegel N, Preisinger C, Boor P, Guldiken N, Krusche CA, Sellge G, Trautwein C, Waschke J, Heuser A, Leube RE, Strnad P"
< "P55292-1","28339476","Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling.","PloS one","2017","Brodehl A, Belke DD, Garnett L, Martens K, Abdelfatah N, Rodriguez M, Diao C, Chen YX, Gordon PM, Nygren A, Gerull B"
< "P55292-1","27834139","MicroRNA-130a Regulation of Desmocollin 2 in a Novel Model of Arrhythmogenic Cardiomyopathy.","MicroRNA (Shariqah, United Arab Emirates)","2017","Mazurek SR, Calway T, Harmon C, Farrell P, Kim GH"
---
> "Q5SRY7-1","30031111","beta-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.","Biochimica et biophysica acta. General subjects","2018 Oct","Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K"
> "Q5SRY7-1","26240281","S6 Kinase- and beta-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.","Molecular and cellular biology","2015 Oct","Nakagawa T, Araki T, Nakagawa M, Hirao A, Unno M, Nakayama K"
> "Q5SRY7-1","18782782","The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2.","Journal of biochemistry","2008 Nov","Ohsaki K, Oishi K, Kozono Y, Nakayama K, Nakayama KI, Ishida N"
7704c8478,8482
< "A2APC3-1","27257088","Ttll9-/- mice sperm flagella show shortening of doublet 7, reduction of doublet 5 polyglutamylation and a stall in beating.","Journal of cell science","2016 Jul 15","Konno A, Ikegami K, Konishi Y, Yang HJ, Abe M, Yamazaki M, Sakimura K, Yao I, Shiba K, Inaba K, Setou M"
---
> "A2A8U2-1","28893537","Cytoplasmic transfer of heritable elements other than mtDNA from SAMP1 mice into mouse tumor cells suppresses their ability to form tumors in C57BL6 mice.","Biochemical and biophysical research communications","2017 Nov 4","Shimizu A, Tani H, Takibuchi G, Ishikawa K, Sakurazawa R, Inoue T, Hashimoto T, Nakada K, Takenaga K, Hayashi JI"
> "A2A8U2-1","28301579","A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis.","PloS one","2017","Menghini P, Di Martino L, Lopetuso LR, Corridoni D, Webster JC, Xin W, Arseneau KO, Lam M, Pizarro TT, Cominelli F"
> "A2A8U2-1","25051721","[Morphological changes of neurons and neuroglial cells in the brain of senescence-accelerated prone 1 (SAMP1) mice].","Arkhiv patologii","2014 Mar-Apr","Khudoerkov RM, Sal'kov VN, Sal'nikova OV, Sobolev VB"
> "A2A8U2-1","23583482","Impaired motor function in senescence-accelerated mouse prone 1 (SAMP1).","Brain research","2013 Jun 17","Aoyama Y, Kim TY, Yoshimoto T, Niimi K, Takahashi E, Itakura C"
> "A2A8U2-1","22349700","Samp1 is a component of TAN lines and is required for nuclear movement.","Journal of cell science","2012 Mar 1","Borrego-Pinto J, Jegou T, Osorio DS, Aurade F, Gorjanacz M, Koch B, Mattaj IW, Gomes ER"
7707,7709c8485
< "Q3TKT4-1","30372823","Brahma-related gene 1 ameliorates the neuronal apoptosis and oxidative stress induced by oxygen-glucose deprivation/reoxygenation through activation of Nrf2/HO-1 signaling.","Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie","2018 Dec","Li F, Liang J, Tang D"
< "Q3TKT4-1","30049497","Brg1 deficiency in vascular endothelial cells blocks neutrophil recruitment and ameliorates cardiac ischemia-reperfusion injury in mice.","International journal of cardiology","2018 Oct 15","Zhang X, Liu S, Weng X, Zeng S, Yu L, Guo J, Xu Y"
< "Q3TKT4-1","30149919","Brg1 aggravates airway inflammation in asthma via inhibition of the PI3K/Akt/mTOR pathway.","Biochemical and biophysical research communications","2018 Sep 18","Zou W, Ding F, Niu C, Fu Z, Liu S"
---
> "Q91V83-1","24657168","Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.","Molecular cell","2014 Apr 10","Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH"
7710a8487
> "D3Z1D3-1","28717008","The novel cardiac z-disc protein CEFIP regulates cardiomyocyte hypertrophy by modulating calcineurin signaling.","The Journal of biological chemistry","2017 Sep 15","Dierck F, Kuhn C, Rohr C, Hille S, Braune J, Sossalla S, Molt S, van der Ven PFM, Furst DO, Frey N"
7729,7735c8506,8507
< "Q9Z188-1","30317528","DYRK1B regulates Hedgehog-induced microtubule acetylation.","Cellular and molecular life sciences : CMLS","2019 Jan","Singh R, Holz PS, Roth K, Hupfer A, Meissner W, Muller R, Buchholz M, Gress TM, Elsasser HP, Jacob R, Lauth M"
< "Q9Z188-1","29030970","Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.","Journal of cellular physiology","2018 May","Perez-Sanchez G, Jimenez A, Quezada-Ramirez MA, Estudillo E, Ayala-Sarmiento AE, Mendoza-Hernandez G, Hernandez-Soto J, Hernandez-Hernandez FC, Cazares-Raga FE, Segovia J"
< "Q9Z188-1","24312406","Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.","PloS one","2013","Tsioras K, Papastefanaki F, Politis PK, Matsas R, Gaitanou M"
< "Q9Z188-1","22711815","Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.","Proceedings of the National Academy of Sciences of the United States of America","2012 Jul 3","Masuda T, Itoh K, Higashitsuji H, Higashitsuji H, Nakazawa N, Sakurai T, Liu Y, Tokuchi H, Fujita T, Zhao Y, Nishiyama H, Tanaka T, Fukumoto M, Ikawa M, Okabe M, Fujita J"
< "Q9Z188-1","18818203","G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.","The Journal of biological chemistry","2008 Dec 5","Janumyan Y, Cui Q, Yan L, Sansam CG, Valentin M, Yang E"
< "Q9Z188-1","12902328","Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation.","The Journal of biological chemistry","2003 Oct 17","Deng X, Ewton DZ, Pawlikowski B, Maimone M, Friedman E"
< "Q9Z188-1","12384504","The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.","The Journal of biological chemistry","2002 Dec 20","Lim S, Zou Y, Friedman E"
---
> "Q9JLJ0-1","29953492","SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.","PloS one","2018","Moriwaki Y, Ohno Y, Ishii T, Takamura Y, Kita Y, Watabe K, Sango K, Tsuji S, Misawa H"
> "Q9QXP7-1","28625919","C1q/TNF-related protein 1 promotes endothelial barrier dysfunction under disturbed flow.","Biochemical and biophysical research communications","2017 Aug 19","Liu ZH, Li C, Chen JW, Shen Y, Gao J, Shen WF, Zhang RY, Wang XQ, Lu L"
7736a8509,8514
> "Q8R1G1-1","30573454","Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia.","Genes &amp; development","2019 Jan 1","Zhao Z, Wang L, Volk AG, Birch NW, Stoltz KL, Bartom ET, Marshall SA, Rendleman EJ, Nestler CM, Shilati J, Schiltz GE, Crispino JD, Shilatifard A"
> "Q8R1G1-1","25664857","Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.","The Journal of clinical investigation","2015 Mar 2","Takeda S, Sasagawa S, Oyama T, Searleman AC, Westergard TD, Cheng EH, Hsieh JJ"
> "Q8R1G1-1","25267403","Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis.","Cell research","2014 Nov","Dong Y, Van Tine BA, Oyama T, Wang PI, Cheng EH, Hsieh JJ"
> "Q8R1G1-1","24176642","Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.","Developmental cell","2013 Oct 28","Oyama T, Sasagawa S, Takeda S, Hess RA, Lieberman PM, Cheng EH, Hsieh JJ"
> "Q8R1G1-1","18395097","EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.","Gastroenterology","2008 Apr","Niehof M, Borlak J"
> "Q8R1G1-1","16951254","Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.","Genes &amp; development","2006 Sep 1","Takeda S, Chen DY, Westergard TD, Fisher JK, Rubens JA, Sasagawa S, Kan JT, Korsmeyer SJ, Cheng EH, Hsieh JJ"
7747a8526
> "Q8BXQ6-1","17803194","Aminopeptidase O contains a functional nucleolar localization signal and is implicated in vascular biology.","Journal of cellular biochemistry","2008 Mar 1","Axton R, Wallis JA, Taylor H, Hanks M, Forrester LM"
7751,7754d8529
< "Q9Z2X1-1","29773655","FOXP3 interacts with hnRNPF to modulate pre-mRNA alternative splicing.","The Journal of biological chemistry","2018 Jun 29","Du J, Wang Q, Ziegler SF, Zhou B"
< "Q9Z2X1-1","28424160","Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice.","Diabetes","2017 Jul","Lo CS, Shi Y, Chenier I, Ghosh A, Wu CH, Cailhier JF, Ethier J, Lattouf JB, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD"
< "Q9Z2X1-1","28324005","Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice.","Endocrinology","2017 Apr 1","Ghosh A, Abdo S, Zhao S, Wu CH, Shi Y, Lo CS, Chenier I, Alquier T, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD"
< "Q9Z2X1-1","26232095","Overexpression of heterogeneous nuclear ribonucleoprotein F stimulates renal Ace-2 gene expression and prevents TGF-beta1-induced kidney injury in a mouse model of diabetes.","Diabetologia","2015 Oct","Lo CS, Shi Y, Chang SY, Abdo S, Chenier I, Filep JG, Ingelfinger JR, Zhang SL, Chan JS"
7756c8531,8533
< "Q9R0N6-1","11751263","Synaptotagmin VIII is localized to the mouse sperm head and may function in acrosomal exocytosis.","Biology of reproduction","2002 Jan","Hutt DM, Cardullo RA, Baltz JM, Ngsee JK"
---
> "Q9JKK7-1","24746171","Role of tropomodulin's leucine rich repeat domain in the formation of neurite-like processes.","Biochemistry","2014 Apr 29","Guillaud L, Gray KT, Moroz N, Pantazis C, Pate E, Kostyukova AS"
> "Q9JKK7-1","12799133","Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory.","Molecular and cellular neurosciences","2003 May","Cox PR, Fowler V, Xu B, Sweatt JD, Paylor R, Zoghbi HY"
> "Q9D1F4-1","12524439","Identification of a proline-rich Akt substrate as a 14-3-3 binding partner.","The Journal of biological chemistry","2003 Mar 21","Kovacina KS, Park GY, Bae SS, Guzzetta AW, Schaefer E, Birnbaum MJ, Roth RA"
7763a8541,8544
> "Q9CPV0-1","28954202","Ciliopathy Protein Tmem107 Plays Multiple Roles in Craniofacial Development.","Journal of dental research","2018 Jan","Cela P, Hampl M, Shylo NA, Christopher KJ, Kavkova M, Landova M, Zikmund T, Weatherbee SD, Kaiser J, Buchtova M"
> "Q9CPV0-1","26518474","TMEM107 Is a Critical Regulator of Ciliary Protein Composition and Is Mutated in Orofaciodigital Syndrome.","Human mutation","2016 Feb","Shylo NA, Christopher KJ, Iglesias A, Daluiski A, Weatherbee SD"
> "Q9CPV0-1","26595381","TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.","Nature cell biology","2016 Jan","Lambacher NJ, Bruel AL, van Dam TJ, Szymanska K, Slaats GG, Kuhns S, McManus GJ, Kennedy JE, Gaff K, Wu KM, van der Lee R, Burglen L, Doummar D, Riviere JB, Faivre L, Attie-Bitach T, Saunier S, Curd A, Peckham M, Giles RH, Johnson CA, Huynen MA, Thauvin-Robinet C, Blacque OE"
> "Q9CPV0-1","22698544","Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.","Developmental biology","2012 Aug 15","Christopher KJ, Wang B, Kong Y, Weatherbee SD"
7773a8555
> "Q9QYP6-1","23610142","Critical role of AZI2 in GM-CSF-induced dendritic cell differentiation.","Journal of immunology (Baltimore, Md. : 1950)","2013 Jun 1","Fukasaka M, Ori D, Kawagoe T, Uematsu S, Maruyama K, Okazaki T, Kozaki T, Imamura T, Tartey S, Mino T, Satoh T, Akira S, Takeuchi O"
7776,7778d8557
< "Q8BG84-1","28887430","The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis.","Journal of immunology (Baltimore, Md. : 1950)","2017 Oct 15","Kim S, Easterling ER, Price LC, Smith SL, Coligan JE, Park JE, Brand DD, Rosloniec EF, Stuart JM, Kang AH, Myers LK"
< "Q8BG84-1","28336561","Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.","Arteriosclerosis, thrombosis, and vascular biology","2017 May","Smith CW, Thomas SG, Raslan Z, Patel P, Byrne M, Lordkipanidze M, Bem D, Meyaard L, Senis YA, Watson SP, Mazharian A"
< "Q8BG84-1","15100296","The mouse homologue of the leukocyte-associated Ig-like receptor-1 is an inhibitory receptor that recruits Src homology region 2-containing protein tyrosine phosphatase (SHP)-2, but not SHP-1.","Journal of immunology (Baltimore, Md. : 1950)","2004 May 1","Lebbink RJ, de Ruiter T, Verbrugge A, Bril WS, Meyaard L"
7779a8559
> "O35405-1","30111894","PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.","Nature immunology","2018 Sep","Gavin AL, Huang D, Huber C, Martensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D"
7786d8565
< "Q61979-1","23527188","Differential pre-mRNA splicing regulates Nnat isoforms in the hypothalamus after gastric bypass surgery in mice.","PloS one","2013","Scott WR, Gelegen C, Chandarana K, Karra E, Yousseif A, Amouyal C, Choudhury AI, Andreelli F, Withers DJ, Batterham RL"
7792a8572
> "Q0P5V9-1","25164149","Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae.","The Biochemical journal","2014 Dec 1","Bartolke R, Heinisch JJ, Wieczorek H, Vitavska O"
7795,7797c8575,8580
< "O88839-1","25650586","A disintegrin and metallproteinase 15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.","Molecular medicine reports","2015 Jun","Gao J, Zheng W, Wang L, Song B"
< "O88839-1","25249606","Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.","Investigative ophthalmology &amp; visual science","2014 Sep 23","Maretzky T, Blobel CP, Guaiquil V"
< "O88839-1","23161886","ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.","American journal of physiology. Lung cellular and molecular physiology","2013 Feb 1","Sun C, Beard RS Jr, McLean DL, Rigor RR, Konia T, Wu MH, Yuan SY"
---
> "A2CG63-1","28207192","Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network.","Stem cells (Dayton, Ohio)","2017 Jun","Wu RC, Zeng Y, Chen YF, Lanz RB, Wu MY"
> "A2CG63-1","26258622","Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.","Molecular endocrinology (Baltimore, Md.)","2015 Sep","Wu RC, Zeng Y, Pan IW, Wu MY"
> "A2CG63-1","23487765","ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.","Proceedings of the National Academy of Sciences of the United States of America","2013 Mar 19","Wu RC, Jiang M, Beaudet AL, Wu MY"
> "A2CG63-1","18728284","Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.","Journal of the National Cancer Institute","2008 Sep 3","Wu MY, Eldin KW, Beaudet AL"
> "P59900-1","22334695","EMILIN-3, peculiar member of elastin microfibril interface-located protein (EMILIN) family, has distinct expression pattern, forms oligomeric assemblies, and serves as transforming growth factor beta (TGF-beta) antagonist.","The Journal of biological chemistry","2012 Mar 30","Schiavinato A, Becker AK, Zanetti M, Corallo D, Milanetto M, Bizzotto D, Bressan G, Guljelmovic M, Paulsson M, Wagener R, Braghetta P, Bonaldo P"
> "P59900-1","17660561","Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.","Genetics","2007 Sep","Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH"
7798a8582
> "Q3UTA8-1","15289607","The mouse kinome: discovery and comparative genomics of all mouse protein kinases.","Proceedings of the National Academy of Sciences of the United States of America","2004 Aug 10","Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G"
7813,7815c8597,8598
< "Q8BUL6-1","27859053","B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.","European journal of immunology","2017 Feb","Jayachandran N, Landego I, Hou S, Alessi DR, Marshall AJ"
< "Q8BUL6-1","26242484","TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway.","Neuroscience bulletin","2015 Oct","Chen Y, Mei R, Teng P, Yang A, Hu X, Zhang Z, Qiu M, Zhao X"
< "Q8BUL6-1","22777911","Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.","European journal of immunology","2012 Oct","Landego I, Jayachandran N, Wullschleger S, Zhang TT, Gibson IW, Miller A, Alessi DR, Marshall AJ"
---
> "Q8VCF0-1","16153868","VISA is an adapter protein required for virus-triggered IFN-beta signaling.","Molecular cell","2005 Sep 16","Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB"
> "Q8VCF0-1","16125763","Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3.","Cell","2005 Sep 9","Seth RB, Sun L, Ea CK, Chen ZJ"
7818a8602
> "Q5DW34-1","16702210","Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP.","The Journal of biological chemistry","2006 Jul 21","Ueda J, Tachibana M, Ikura T, Shinkai Y"
7823,7824c8607,8610
< "P97797-1","30770827","A functional subset of CD8(+) T cells during chronic exhaustion is defined by SIRPalpha expression.","Nature communications","2019 Feb 15","Myers LM, Tal MC, Torrez Dulgeroff LB, Carmody AB, Messer RJ, Gulati G, Yiu YY, Staron MM, Angel CL, Sinha R, Markovic M, Pham EA, Fram B, Ahmed A, Newman AM, Glenn JS, Davis MM, Kaech SM, Weissman IL, Hasenkrug KJ"
< "P97797-1","30602457","Microglia are effector cells of CD47-SIRPalpha antiphagocytic axis disruption against glioblastoma.","Proceedings of the National Academy of Sciences of the United States of America","2019 Jan 15","Hutter G, Theruvath J, Graef CM, Zhang M, Schoen MK, Manz EM, Bennett ML, Olson A, Azad TD, Sinha R, Chan C, Assad Kahn S, Gholamin S, Wilson C, Grant G, He J, Weissman IL, Mitra SS, Cheshier SH"
---
> "Q3UUV5-1","27181093","T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice.","Immunology letters","2016 Aug","Smith X, Taylor A, Rudd CE"
> "Q3UUV5-1","26905930","Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.","Immunology letters","2016 Apr","Lim D, Lu Y, Rudd CE"
> "Q3UUV5-1","25851535","ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy.","EMBO molecular medicine","2015 Jun","Li C, Li W, Xiao J, Jiao S, Teng F, Xue S, Zhang C, Sheng C, Leng Q, Rudd CE, Wei B, Wang H"
> "Q3UUV5-1","17646386","Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion.","Molecular and cellular biology","2007 Oct","Wang H, Liu H, Lu Y, Lovatt M, Wei B, Rudd CE"
7833,7834d8618
< "Q9Z0L2-1","28270618","Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.","Proceedings of the National Academy of Sciences of the United States of America","2017 Mar 21","Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G"
< "Q9Z0L2-1","25635057","Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels.","The Journal of biological chemistry","2015 Apr 17","Li S, Bhave D, Chow JM, Riera TV, Schlee S, Rauch S, Atanasova M, Cate RL, Whitty A"
7837a8622
> "Q9WTX7-1","20488182","Sperm associated antigen 8 (SPAG8), a novel regulator of activator of CREM in testis during spermatogenesis.","FEBS letters","2010 Jul 2","Wu H, Chen Y, Miao S, Zhang C, Zong S, Koide SS, Wang L"
7843a8629
> "Q9DAJ2-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
7848a8635,8641
> "Q18PE0-1","28069867","The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation.","Journal of biochemistry","2017 Mar 1","Ueta R, Tezuka T, Izawa Y, Miyoshi S, Nagatoishi S, Tsumoto K, Yamanashi Y"
> "Q18PE0-1","27091576","Postnatal knockdown of dok-7 gene expression in mice causes structural defects in neuromuscular synapses and myasthenic pathology.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2016 Jun","Eguchi T, Tezuka T, Miyoshi S, Yamanashi Y"
> "Q18PE0-1","26198629","Protein kinase CK2 interacts at the neuromuscular synapse with Rapsyn, Rac1, 14-3-3gamma, and Dok-7 proteins and phosphorylates the latter two.","The Journal of biological chemistry","2015 Sep 11","Herrmann D, Straubinger M, Hashemolhosseini S"
> "Q18PE0-1","18165682","Mutations causing DOK7 congenital myasthenia ablate functional motifs in Dok-7.","The Journal of biological chemistry","2008 Feb 29","Hamuro J, Higuchi O, Okada K, Ueno M, Iemura S, Natsume T, Spearman H, Beeson D, Yamanashi Y"
> "Q18PE0-1","16794080","The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.","Science (New York, N.Y.)","2006 Jun 23","Okada K, Inoue A, Okada M, Murata Y, Kakuta S, Jigami T, Kubo S, Shiraishi H, Eguchi K, Motomura M, Akiyama T, Iwakura Y, Higuchi O, Yamanashi Y"
> "P07356-1","29030970","Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.","Journal of cellular physiology","2018 May","Perez-Sanchez G, Jimenez A, Quezada-Ramirez MA, Estudillo E, Ayala-Sarmiento AE, Mendoza-Hernandez G, Hernandez-Soto J, Hernandez-Hernandez FC, Cazares-Raga FE, Segovia J"
> "P10923-1","30639873","Osteopontin potentiates PM-induced IL-1alpha and IL-1beta production via the ERK/JNK signaling pathway.","Ecotoxicology and environmental safety","2019 Apr 30","Wang J, Huang J, Zhu M, Chen S, Chen C, Miao C, He H, Song Y"
7852c8645
< "Q8R242-1","22465033","Lysosomal di-N-acetylchitobiase-deficient mouse tissues accumulate Man2GlcNAc2 and Man3GlcNAc2.","Biochimica et biophysica acta","2012 Jul","Persichetti E, Klein K, Paciotti S, Lecointe K, Balducci C, Franken S, Duvet S, Matzner U, Roberti R, Hartmann D, Gieselmann V, Beccari T"
---
> "Q69Z26-1","27539848","Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.","The Journal of biological chemistry","2016 Oct 7","Nikolaienko RM, Hammel M, Dubreuil V, Zalmai R, Hall DR, Mehzabeen N, Karuppan SJ, Harroch S, Stella SL, Bouyain S"
7860,7865d8652
< "Q8R0I0-1","29679094","Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response.","Cellular and molecular life sciences : CMLS","2018 Oct","Klempin F, Mosienko V, Matthes S, Villela DC, Todiras M, Penninger JM, Bader M, Santos RAS, Alenina N"
< "Q8R0I0-1","29990483","Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.","Life sciences","2018 Sep 1","Liu J, Chen Q, Liu S, Yang X, Zhang Y, Huang F"
< "Q8R0I0-1","29884907","Sex dimorphism in ANGII-mediated crosstalk between ACE2 and ACE in diabetic nephropathy.","Laboratory investigation; a journal of technical methods and pathology","2018 Sep","Clotet-Freixas S, Soler MJ, Palau V, Anguiano L, Gimeno J, Konvalinka A, Pascual J, Riera M"
< "Q8R0I0-1","15452268","Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.","Journal of virology","2004 Oct","Li W, Greenough TC, Moore MJ, Vasilieva N, Somasundaran M, Sullivan JL, Farzan M, Choe H"
< "Q8R0I0-1","12487024","Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2).","DNA sequence : the journal of DNA sequencing and mapping","2002 Aug","Komatsu T, Suzuki Y, Imai J, Sugano S, Hida M, Tanigami A, Muroi S, Yamada Y, Hanaoka K"
< "Q8R0I0-1","12075344","Angiotensin-converting enzyme 2 is an essential regulator of heart function.","Nature","2002 Jun 20","Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM"
7866a8654,8656
> "A2AJL3-1","29220483","Prenatal Exposure to Bisphenol A Disrupts Naturally Occurring Bimodal DNA Methylation at Proximal Promoter of fggy, an Obesity-Relevant Gene Encoding a Carbohydrate Kinase, in Gonadal White Adipose Tissues of CD-1 Mice.","Endocrinology","2018 Feb 1","Taylor JA, Shioda K, Mitsunaga S, Yawata S, Angle BM, Nagel SC, Vom Saal FS, Shioda T"
> "Q8BYK6-1","30591559","RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation.","Proceedings of the National Academy of Sciences of the United States of America","2019 Jan 15","Zhang Y, Wang X, Zhang X, Wang J, Ma Y, Zhang L, Cao X"
> "Q6P549-1","29749928","Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.","eLife","2018 May 11","Wang Y, Shang Y, Li J, Chen W, Li G, Wan J, Liu W, Zhang M"
7867a8658
> "Q8C5H8-1","23616928","MNADK, a novel liver-enriched mitochondrion-localized NAD kinase.","Biology open","2013 Apr 15","Zhang R"
7869a8661
> "Q8BZN6-1","21514340","Human and mouse DOCK10 splicing isoforms with alternative first coding exon usage are differentially expressed in T and B lymphocytes.","Human immunology","2011 Jul","Alcaraz-Garcia MJ, Ruiz-Lafuente N, Sebastian-Ruiz S, Majado MJ, Gonzalez-Garcia C, Bernardo MV, Alvarez-Lopez MR, Parrado A"
7871,7872d8662
< "P97438-1","28839101","Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins.","American journal of physiology. Lung cellular and molecular physiology","2017 Dec 1","Schwingshackl A, Lopez B, Teng B, Luellen C, Lesage F, Belperio J, Olcese R, Waters CM"
< "P97438-1","29042297","TREK-1 pathway mediates isoflurane-induced memory impairment in middle-aged mice.","Neurobiology of learning and memory","2017 Nov","Cai Y, Peng Z, Guo H, Wang F, Zeng Y"
7880,7884c8670,8671
< "Q69ZN7-1","20571050","Myoferlin regulation by NFAT in muscle injury, regeneration and repair.","Journal of cell science","2010 Jul 15","Demonbreun AR, Lapidos KA, Heretis K, Levin S, Dale R, Pytel P, Svensson EC, McNally EM"
< "Q69ZN7-1","20008164","Myoferlin is required for insulin-like growth factor response and muscle growth.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2010 Apr","Demonbreun AR, Posey AD, Heretis K, Swaggart KA, Earley JU, Pytel P, McNally EM"
< "Q69ZN7-1","17702744","Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.","The Journal of biological chemistry","2007 Oct 19","Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC"
< "Q69ZN7-1","16280346","Normal myoblast fusion requires myoferlin.","Development (Cambridge, England)","2005 Dec","Doherty KR, Cave A, Davis DB, Delmonte AJ, Posey A, Earley JU, Hadhazy M, McNally EM"
< "Q69ZN7-1","11959863","Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.","The Journal of biological chemistry","2002 Jun 21","Davis DB, Doherty KR, Delmonte AJ, McNally EM"
---
> "Q99PV8-1","12717433","Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.","Nature immunology","2003 Jun","Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, Mishima Y, Hitomi J, Yamamoto T, Utsuyama M, Niwa O, Aizawa S, Kominami R"
> "Q99PV8-1","12565905","Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas.","Biochemical and biophysical research communications","2003 Feb 7","Wakabayashi Y, Inoue J, Takahashi Y, Matsuki A, Kosugi-Okano H, Shinbo T, Mishima Y, Niwa O, Kominami R"
7892,7893d8678
< "P27546-1","30327268","Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.","EBioMedicine","2018 Nov","Li L, Zhang Q, Zhang X, Zhang J, Wang X, Ren J, Jia J, Zhang D, Jiang X, Zhang J, Mei H, Chen B, Hu J, Huang Y"
< "P27546-1","25898002","A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation.","eLife","2015 Apr 21","Mogessie B, Roth D, Rahil Z, Straube A"
7907a8693,8703
> "Q64GA5-1","30161143","Augmented Pla2g4c/Ptgs2/Hpgds axis in bronchial smooth muscle tissues of experimental asthma.","PloS one","2018","Chiba Y, Suto W, Sakai H"
> "Q64GA5-1","22082005","Induction of group IVC phospholipase A2 in allergic asthma: transcriptional regulation by TNFalpha in bronchoepithelial cells.","The Biochemical journal","2012 Feb 15","Bickford JS, Newsom KJ, Herlihy JD, Mueller C, Keeler B, Qiu X, Walters JN, Su N, Wallet SM, Flotte TR, Nick HS"
> "Q64GA5-1","20817734","Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.","The Journal of biological chemistry","2010 Nov 19","Mancuso DJ, Sims HF, Yang K, Kiebish MA, Su X, Jenkins CM, Guan S, Moon SH, Pietka T, Nassir F, Schappe T, Moore K, Han X, Abumrad NA, Gross RW"
> "Q64GA5-1","20452986","cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis.","The Journal of biological chemistry","2010 Jul 9","Vignola MJ, Kashatus DF, Taylor GA, Counter CM, Valdivia RH"
> "Q64GA5-1","17213206","Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.","The Journal of biological chemistry","2007 Mar 23","Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW"
> "Q8K3J5-1","29750959","A BTB-ZF protein, ZNF131, is required for early B cell development.","Biochemical and biophysical research communications","2018 Jun 22","Iguchi T, Miyauchi E, Watanabe S, Masai H, Miyatake S"
> "Q8K3J5-1","28882591","The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.","Biochemical and biophysical research communications","2017 Nov 4","Robinson SC, Donaldson-Kabwe NS, Dvorkin-Gheva A, Longo J, He L, Daniel JM"
> "Q8K3J5-1","26136427","BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.","Journal of immunology (Baltimore, Md. : 1950)","2015 Aug 1","Iguchi T, Aoki K, Ikawa T, Taoka M, Taya C, Yoshitani H, Toma-Hirano M, Koiwai O, Isobe T, Kawamoto H, Masai H, Miyatake S"
> "Q8K3J5-1","20303951","Kaiso regulates Znf131-mediated transcriptional activation.","Experimental cell research","2010 Jun 10","Donaldson NS, Nordgaard CL, Pierre CC, Kelly KF, Robinson SC, Swystun L, Henriquez R, Graham M, Daniel JM"
> "Q8K3J5-1","17306895","Nuclear trafficking of the POZ-ZF protein Znf131.","Biochimica et biophysica acta","2007 Apr","Donaldson NS, Daniel Y, Kelly KF, Graham M, Daniel JM"
> "Q8K3J5-1","12163020","The murine BTB/POZ zinc finger gene Znf131: predominant expression in the developing central nervous system, in adult brain, testis, and thymus.","Biochemical and biophysical research communications","2002 Aug 16","Trappe R, Buddenberg P, Uedelhoven J, Glaser B, Buck A, Engel W, Burfeind P"
7908a8705,8708
> "Q64702-1","28972102","Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes.","The Journal of cell biology","2017 Nov 6","Bury L, Coelho PA, Simeone A, Ferries S, Eyers CE, Eyers PA, Zernicka-Goetz M, Glover DM"
> "Q64702-1","26595384","Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis.","Nature cell biology","2016 Jan","Sercin O, Larsimont JC, Karambelas AE, Marthiens V, Moers V, Boeckx B, Le Mercier M, Lambrechts D, Basto R, Blanpain C"
> "Q64702-1","26439168","Loss of KLF14 triggers centrosome amplification and tumorigenesis.","Nature communications","2015 Oct 6","Fan G, Sun L, Shan P, Zhang X, Huan J, Zhang X, Li D, Wang T, Wei T, Zhang X, Gu X, Yao L, Xuan Y, Hou Z, Cui Y, Cao L, Li X, Zhang S, Wang C"
> "Q64702-1","12352953","The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization.","Nature structural biology","2002 Oct","Leung GC, Hudson JW, Kozarova A, Davidson A, Dennis JW, Sicheri F"
7919,7922d8718
< "Q91WT8-1","30309881","Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver.","RNA (New York, N.Y.)","2019 Jan","Blanc V, Xie Y, Kennedy S, Riordan JD, Rubin DC, Madison BB, Mills JC, Nadeau JH, Davidson NO"
< "Q91WT8-1","26789794","Conditional restoration and inactivation of Rbm47 reveal its tissue-context requirement for viability and growth.","Genesis (New York, N.Y. : 2000)","2016 Mar","Fossat N, Radziewic T, Jones V, Tourle K, Tam PP"
< "Q91WT8-1","24916387","C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.","EMBO reports","2014 Aug","Fossat N, Tourle K, Radziewic T, Barratt K, Liebhold D, Studdert JB, Power M, Jones V, Loebel DA, Tam PP"
< "Q91WT8-1","23649762","RNA-binding protein Rbm47 binds to Nanog in mouse embryonic stem cells.","Molecular biology reports","2013 Jul","Yeganeh M, Seyedjafari E, Kamrani FA, Ghaemi N"
7929,7931c8725
< "Q71M36-1","24265546","Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/ chondroitin sulfate proteoglycan 5.","Molecular vision","2013","Cottet S, Juttner R, Voirol N, Chambon P, Rathjen FG, Schorderet DF, Escher P"
< "Q71M36-1","23889129","Impaired presynaptic function and elimination of synapses at premature stages during postnatal development of the cerebellum in the absence of CALEB (CSPG5/neuroglycan C).","The European journal of neuroscience","2013 Nov","Juttner R, Montag D, Craveiro RB, Babich A, Vetter P, Rathjen FG"
< "Q71M36-1","11929867","Phosphorylation of neuroglycan C, a brain-specific transmembrane chondroitin sulfate proteoglycan, and its localization in the lipid rafts.","The Journal of biological chemistry","2002 Jun 7","Yamauchi S, Tokita Y, Aono S, Matsui F, Shuo T, Ito H, Kato K, Kasahara K, Oohira A"
---
> "A2A9T0-1","17568778","SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK.","The EMBO journal","2007 Jul 11","Ryzhakov G, Randow F"
7936a8731
> "Q3TY86-1","19280713","Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria.","Free radical biology &amp; medicine","2009 Apr 1","Chinta SJ, Rane A, Yadava N, Andersen JK, Nicholls DG, Polster BM"
7942d8736
< "Q6P3A8-1","16875466","Impaired growth and neurological abnormalities in branched-chain alpha-keto acid dehydrogenase kinase-deficient mice.","The Biochemical journal","2006 Nov 15","Joshi MA, Jeoung NH, Obayashi M, Hattab EM, Brocken EG, Liechty EA, Kubek MJ, Vattem KM, Wek RC, Harris RA"
7946,7948d8739
< "Q9WV69-1","27073223","Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia.","Blood","2016 Jul 7","Lu Y, Hanada T, Fujiwara Y, Nwankwo JO, Wieschhaus AJ, Hartwig J, Huang S, Han J, Chishti AH"
< "Q9WV69-1","23060452","Headpiece domain of dematin regulates calcium mobilization and signaling in platelets.","The Journal of biological chemistry","2012 Nov 30","Wieschhaus AJ, Le Breton GC, Chishti AH"
< "Q9WV69-1","21084299","Dematin, a component of the erythrocyte membrane skeleton, is internalized by the malaria parasite and associates with Plasmodium 14-3-3.","The Journal of biological chemistry","2011 Jan 14","Lalle M, Curra C, Ciccarone F, Pace T, Cecchetti S, Fantozzi L, Ay B, Breton CB, Ponzi M"
7949a8741
> "Q811W2-1","11744378","Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis.","Mechanisms of development","2002 Jan","Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dolle P"
7977a8770
> "Q9D0M5-1","22328512","GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity.","Journal of cell science","2012 Apr 15","Moutin E, Raynaud F, Fagni L, Perroy J"
7982a8776,8777
> "P05017-1","30915127","miR-29b-3p regulated osteoblast differentiation via regulating IGF-1 secretion of mechanically stimulated osteocytes.","Cellular &amp; molecular biology letters","2019","Zeng Q, Wang Y, Gao J, Yan Z, Li Z, Zou X, Li Y, Wang J, Guo Y"
> "P05017-1","30808767","Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration.","Proceedings of the National Academy of Sciences of the United States of America","2019 Feb 26","Pristera A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, Cragg S, Guillemot F, Ang SL"
7984,7987d8778
< "P70451-1","27401557","HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer.","Genes &amp; development","2016 Jul 1","Fan G, Zhang S, Gao Y, Greer PA, Tonks NK"
< "P70451-1","27226326","The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm.","Development (Cambridge, England)","2016 Jul 1","Alvau A, Battistone MA, Gervasi MG, Navarrete FA, Xu X, Sanchez-Cardenas C, De la Vega-Beltran JL, Da Ros VG, Greer PA, Darszon A, Krapf D, Salicioni AM, Cuasnicu PS, Visconti PE"
< "P70451-1","25237066","Oncogenic properties of a spermatogenic meiotic variant of fer kinase expressed in somatic cells.","Cancer research","2014 Nov 15","Yaffe E, Hikri E, Elkis Y, Cohen O, Segal A, Makovski A, Varvak A, Shpungin S, Nir U"
< "P70451-1","23589302","The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.","The Journal of biological chemistry","2013 May 31","Lennartsson J, Ma H, Wardega P, Pelka K, Engstrom U, Hellberg C, Heldin CH"
7995d8785
< "Q60936-1","27499294","Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.","Molecular cell","2016 Aug 18","Stefely JA, Licitra F, Laredj L, Reidenbach AG, Kemmerer ZA, Grangeray A, Jaeg-Ehret T, Minogue CE, Ulbrich A, Hutchins PD, Wilkerson EM, Ruan Z, Aydin D, Hebert AS, Guo X, Freiberger EC, Reutenauer L, Jochem A, Chergova M, Johnson IE, Lohman DC, Rush MJP, Kwiecien NW, Singh PK, Schlagowski AI, Floyd BJ, Forsman U, Sindelar PJ, Westphall MS, Pierrel F, Zoll J, Dal Peraro M, Kannan N, Bingman CA, Coon JJ, Isope P, Puccio H, Pagliarini DJ"
8001a8792
> "Q8K214-1","23207902","Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.","Molecular and cellular biology","2013 Feb","Yasunaga S, Ohtsubo M, Ohno Y, Saeki K, Kurogi T, Tanaka-Okamoto M, Ishizaki H, Shirai M, Mihara K, Brock HW, Miyoshi J, Takihara Y"
8002a8794,8795
> "Q99KU0-1","28890335","The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.","Molecular cell","2017 Sep 21","Zhao YG, Chen Y, Miao G, Zhao H, Qu W, Li D, Wang Z, Liu N, Li L, Chen S, Liu P, Feng D, Zhang H"
> "Q99KU0-1","27415425","The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation.","Cell death &amp; disease","2016 Jul 14","Loncle C, Molejon MI, Lac S, Tellechea JI, Lomberk G, Gramatica L, Fernandez Zapico MF, Dusetti N, Urrutia R, Iovanna JL"
8004a8798,8801
> "P97792-1","31083261","CEACAM-1 promotes myocardial injury following coxsackievirus infection by regulating the coxsackievirus-adenovirus receptor.","Medicine","2019 May","Zhang Z, Long C, Li X, Xie Q, Song M, Zhang Y"
> "P97792-1","28381574","Defining a Novel Role for the Coxsackievirus and Adenovirus Receptor in Human Adenovirus Serotype 5 Transduction In Vitro in the Presence of Mouse Serum.","Journal of virology","2017 Jun 15","Lopez-Gordo E, Doszpoly A, Duffy MR, Coughlan L, Bradshaw AC, White KM, Denby L, Nicklin SA, Baker AH"
> "P97792-1","21674029","Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene.","PloS one","2011","Pazirandeh A, Sultana T, Mirza M, Rozell B, Hultenby K, Wallis K, Vennstrom B, Davis B, Arner A, Heuchel R, Lohr M, Philipson L, Sollerbrant K"
> "P97792-1","12823902","Structure and chromosomal localization of the murine coxsackievirus and adenovirus receptor gene.","DNA and cell biology","2003 Apr","Chen JW, Ghosh R, Finberg RW, Bergelson JM"
8008a8806
> "Q6PG16-1","26149421","Divergence patterns of genic copy number variation in natural populations of the house mouse (Mus musculus domesticus) reveal three conserved genes with major population-specific expansions.","Genome research","2015 Aug","Pezer Z, Harr B, Teschke M, Babiker H, Tautz D"
8010a8809
> "Q5DTW7-1","29728365","A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.","Genome research","2018 Jun","Fukuda K, Okuda A, Yusa K, Shinkai Y"
8016a8816,8822
> "Q80V23-1","25032857","Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere maintenance.","Cell death &amp; disease","2014 Jul 17","Gao B, Li K, Wei YY, Zhang J, Li J, Zhang L, Gao JP, Li YY, Huang LG, Lin P, Wei YQ"
> "Q80V23-1","20235149","A novel zinc finger protein Zfp637 behaves as a repressive regulator in myogenic cellular differentiation.","Journal of cellular biochemistry","2010 May 15","Li K, Zhang J, Ren JJ, Wang Q, Yang KY, Xiong ZJ, Mao YQ, Qi YY, Chen XW, Lan F, Wang XJ, Xiao HY, Lin P, Wei YQ"
> "Q811P8-1","30045817","The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice.","EBioMedicine","2018 Aug","Nakamura T, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akiyama T"
> "Q811P8-1","17663722","PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2007 Aug","Hayashi T, Okabe T, Nasu-Nishimura Y, Sakaue F, Ohwada S, Matsuura K, Akiyama T, Nakamura T"
> "Q811P8-1","17272280","p200 RhoGAP promotes cell proliferation by mediating cross-talk between Ras and Rho signaling pathways.","The Journal of biological chemistry","2007 Mar 23","Shang X, Moon SY, Zheng Y"
> "Q811P8-1","16716191","Role of the Rho GTPase-activating protein RICS in neurite outgrowth.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2006 Jun","Nasu-Nishimura Y, Hayashi T, Ohishi T, Okabe T, Ohwada S, Hasegawa Y, Senda T, Toyoshima C, Nakamura T, Akiyama T"
> "Q811P8-1","12531901","RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.","The Journal of biological chemistry","2003 Mar 14","Okabe T, Nakamura T, Nishimura YN, Kohu K, Ohwada S, Morishita Y, Akiyama T"
8020,8025c8826
< "Q8R1R4-1","30573681","Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells.","The Journal of biological chemistry","2019 Feb 15","Ogawa S, Matsuoka Y, Takada M, Matsui K, Yamane F, Kubota E, Yasuhara S, Hieda K, Kanayama N, Hatano N, Tokumitsu H, Magari M"
< "Q8R1R4-1","27865758","Bone Morphogenetic Protein 2 and Transforming Growth Factor beta1 Inhibit the Expression of the Proinflammatory Cytokine IL-34 in Rheumatoid Arthritis Synovial Fibroblasts.","The American journal of pathology","2017 Jan","Chemel M, Brion R, Segaliny AI, Lamora A, Charrier C, Brulin B, Maugars Y, Le Goff B, Heymann D, Verrecchia F"
< "Q8R1R4-1","21494622","The critical role of IL-34 in osteoclastogenesis.","PloS one","2011 Apr 8","Chen Z, Buki K, Vaaraniemi J, Gu G, Vaananen HK"
< "Q8R1R4-1","20504948","Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.","Journal of leukocyte biology","2010 Sep","Wei S, Nandi S, Chitu V, Yeung YG, Yu W, Huang M, Williams LT, Lin H, Stanley ER"
< "P17047-1","30048497","Inhibitors of lysosomal function or serum starvation in control or LAMP2 deficient cells do not modify the cellular levels of Parkinson disease-associated DJ-1/PARK 7 protein.","PloS one","2018","Sanchez-Lanzas R, Castano JG"
< "P17047-1","30068868","The Major Lysosomal Membrane Proteins LAMP-1 and LAMP-2 Participate in Differentiation of C2C12 Myoblasts.","Biological &amp; pharmaceutical bulletin","2018","Sakane H, Akasaki K"
---
> "O35125-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
8027,8032c8828,8830
< "Q9R007-3","29126450","The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival.","Journal of translational medicine","2017 Nov 10","Xiong W, Wang H, Lu L, Xi R, Wang F, Gu G, Tao R"
< "Q9R007-3","28824166","CLEC5A is a critical receptor in innate immunity against Listeria infection.","Nature communications","2017 Aug 21","Chen ST, Li FJ, Hsu TY, Liang SM, Yeh YC, Liao WY, Chou TY, Chen NJ, Hsiao M, Yang WB, Hsieh SL"
< "Q9R007-3","27795434","CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo.","Journal of virology","2017 Jan 1","Teng O, Chen ST, Hsu TL, Sia SF, Cole S, Valkenburg SA, Hsu TY, Zheng JT, Tu W, Bruzzone R, Peiris JSM, Hsieh SL, Yen HL"
< "Q9R007-3","27033255","CLEC5A is critical for dengue virus-induced osteoclast activation and bone homeostasis.","Journal of molecular medicine (Berlin, Germany)","2016 Sep","Huang YL, Chen ST, Liu RS, Chen YH, Lin CY, Huang CH, Shu PY, Liao CL, Hsieh SL"
< "Q9R007-3","26927798","Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies.","Journal of immunology (Baltimore, Md. : 1950)","2016 Apr 15","Wortham BW, Eppert BL, Flury JL, Garcia SM, Donica WR, Osterburg A, Joyce-Shaikh B, Cua DJ, Borchers MT"
< "Q9R007-3","19074552","Expression and functional role of MDL-1 (CLEC5A) in mouse myeloid lineage cells.","Journal of leukocyte biology","2009 Mar","Aoki N, Kimura Y, Kimura S, Nagato T, Azumi M, Kobayashi H, Sato K, Tateno M"
---
> "Q9WU00-1","30333037","Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.","Molecular neurodegeneration","2018 Oct 17","Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA"
> "Q9WU00-1","30261697","Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues.","International journal of molecular sciences","2018 Sep 27","Yuan J, Wang H, Xiang Y, Hu S, Li S, Wang M, Qiu L, Zhang Y"
> "Q9WU00-1","29625129","A negative feedback loop between microRNA-378 and Nrf1 promotes the development of hepatosteatosis in mice treated with a high fat diet.","Metabolism: clinical and experimental","2018 Aug","Zhang T, Zhao X, Steer CJ, Yan G, Song G"
8046,8048c8844,8845
< "Q62393-1","28798933","Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.","BioMed research international","2017","Ito C, Mukudai Y, Itose M, Kato K, Motohashi H, Shimane T, Kondo S, Shirota T"
< "Q62393-1","26183179","TPD52 expression increases neutral lipid storage within cultured cells.","Journal of cell science","2015 Sep 1","Kamili A, Roslan N, Frost S, Cantrill LC, Wang D, Della-Franca A, Bright RK, Groblewski GE, Straub BK, Hoy AJ, Chen Y, Byrne JA"
< "Q62393-1","17314271","Induction of tumorigenesis and metastasis by the murine orthologue of tumor protein D52.","Molecular cancer research : MCR","2007 Feb","Lewis JD, Payton LA, Whitford JG, Byrne JA, Smith DI, Yang L, Bright RK"
---
> "Q18PI6-1","27452524","CD84 mediates CLL-microenvironment interactions.","Oncogene","2017 Feb 2","Marom A, Barak AF, Kramer MP, Lewinsky H, Binsky-Ehrenreich I, Cohen S, Tsitsou-Kampeli A, Kalchenko V, Kuznetsov Y, Mirkin V, Dezorella N, Shapiro M, Schwartzberg PL, Cohen Y, Shvidel L, Haran M, Becker-Herman S, Herishanu Y, Shachar I"
> "Q18PI6-1","27223891","CRISPR-Mediated Slamf1Delta/Delta Slamf5Delta/Delta Slamf6Delta/Delta Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects.","PloS one","2016","Hu JK, Crampton JC, Locci M, Crotty S"
8049a8847
> "P97808-1","27006401","FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells.","The Journal of biological chemistry","2016 May 20","Lubarski-Gotliv I, Asher C, Dada LA, Garty H"
8054a8853,8854
> "Q9CPV9-1","29916540","Montelukast inhibits RANKLinduced osteoclast formation and bone loss via CysLTR1 and P2Y12.","Molecular medicine reports","2018 Aug","Kang JH, Lim H, Lee DS, Yim M"
> "P59240-1","12205563","A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution.","American journal of human genetics","2002 Nov","Otto E, Hoefele J, Ruf R, Mueller AM, Hiller KS, Wolf MT, Schuermann MJ, Becker A, Birkenhager R, Sudbrak R, Hennies HC, Nurnberg P, Hildebrandt F"
8056,8058d8855
< "Q9Z1B3-1","27776973","PLC-beta1 and cell differentiation: An insight into myogenesis and osteogenesis.","Advances in biological regulation","2017 Jan","Ramazzotti G, Faenza I, Fiume R, Billi AM, Manzoli L, Mongiorgi S, Ratti S, McCubrey JA, Suh PG, Cocco L, Follo MY"
< "Q9Z1B3-1","27563828","IPMK and beta-catenin mediate PLC-beta1-dependent signaling in myogenic differentiation.","Oncotarget","2016 Dec 20","Ramazzotti G, Billi AM, Manzoli L, Mazzetti C, Ruggeri A, Erneux C, Kim S, Suh PG, Cocco L, Faenza I"
< "Q9Z1B3-1","27342861","Phospholipase Cbeta1 induces membrane tubulation and is involved in caveolae formation.","Proceedings of the National Academy of Sciences of the United States of America","2016 Jul 12","Inaba T, Kishimoto T, Murate M, Tajima T, Sakai S, Abe M, Makino A, Tomishige N, Ishitsuka R, Ikeda Y, Takeoka S, Kobayashi T"
8067a8865
> "P63084-1","24692514","Activity-dependent genes in mouse olfactory sensory neurons.","Chemical senses","2014 Jun","Fischl AM, Heron PM, Stromberg AJ, McClintock TS"
8068a8867,8868
> "Q99JA4-1","29916540","Montelukast inhibits RANKLinduced osteoclast formation and bone loss via CysLTR1 and P2Y12.","Molecular medicine reports","2018 Aug","Kang JH, Lim H, Lee DS, Yim M"
> "Q99JA4-1","11932261","Targeted gene disruption reveals the role of cysteinyl leukotriene 1 receptor in the enhanced vascular permeability of mice undergoing acute inflammatory responses.","The Journal of biological chemistry","2002 Jun 7","Maekawa A, Austen KF, Kanaoka Y"
8071,8072d8870
< "Q8R0S4-3","27003325","Loss of the calcium channel beta4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice.","The European journal of neuroscience","2016 Jun","Benedetti B, Benedetti A, Flucher BE"
< "Q8R0S4-3","24875574","The juvenile myoclonic epilepsy mutant of the calcium channel beta(4) subunit displays normal nuclear targeting in nerve and muscle cells.","Channels (Austin, Tex.)","2014","Etemad S, Campiglio M, Obermair GJ, Flucher BE"
8083c8881,8888
< "P62881-1","28687610","Regulator of G-protein signaling Gbeta5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2017 Nov","Wang Q, Pronin AN, Levay K, Almaca J, Fornoni A, Caicedo A, Slepak VZ"
---
> "Q8BUG5-1","28963059","CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus.","Neuroscience letters","2017 Nov 20","Yagishita K, Suzuki R, Mizuno S, Katoh-Semba R, Sadakata T, Sano Y, Furuichi T, Shinoda Y"
> "Q8BUG5-1","25754523","Lack of stress responses to long-term effects of corticosterone in Caps2 knockout mice.","Scientific reports","2015 Mar 10","Mishima Y, Shinoda Y, Sadakata T, Kojima M, Wakana S, Furuichi T"
> "Q8BUG5-1","25437547","Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.","Cell reports","2014 Nov 6","Nguyen Truong CQ, Nestvogel D, Ratai O, Schirra C, Stevens DR, Brose N, Rhee J, Rettig J"
> "Q8BUG5-1","22111578","Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.","The FEBS journal","2012 Feb","Sadakata T, Sekine Y, Oka M, Itakura M, Takahashi M, Furuichi T"
> "Q8BUG5-1","21173225","Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network.","Proceedings of the National Academy of Sciences of the United States of America","2011 Jan 4","Shinoda Y, Sadakata T, Nakao K, Katoh-Semba R, Kinameri E, Furuya A, Yanagawa Y, Hirase H, Furuichi T"
> "Q8BUG5-1","20302894","Ca(2+)-dependent activator protein for secretion 2 and autistic-like phenotypes.","Neuroscience research","2010 Jul","Sadakata T, Furuichi T"
> "Q8BUG5-1","19238500","Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.","Cerebellum (London, England)","2009 Sep","Sadakata T, Furuichi T"
> "Q8BUG5-1","11846421","Cloning, characterization, and expression of calcyphosine 2, a novel human gene encoding an EF-hand Ca(2+)-binding protein.","Biochemical and biophysical research communications","2002 Feb 22","Wang S, Chen JZ, Zhang Z, Huang Q, Gu S, Ying K, Xie Y, Mao Y"
8093a8899,8900
> "O08795-1","22337885","TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis.","The Journal of biological chemistry","2012 Apr 6","Yaguchi H, Okumura F, Takahashi H, Kano T, Kameda H, Uchigashima M, Tanaka S, Watanabe M, Sasaki H, Hatakeyama S"
> "O08795-1","21995826","A cis-acting region in the N-methyl-d-aspartate R1 3'-untranslated region interacts with the novel RNA-binding proteins beta subunit of alpha glucosidase II and annexin A2--effect of chronic ethanol exposure in vivo.","The European journal of neuroscience","2011 Oct","Anji A, Kumari M"
8100a8908
> "Q8C181-1","29735517","Opposing roles of miR-294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cells.","EMBO reports","2018 Jun","Wu DR, Gu KL, Yu JC, Fu X, Wang XW, Guo WT, Liao LQ, Zhu H, Zhang XS, Hui J, Wang Y"
8107a8916
> "Q9D2C7-1","29457838","Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice.","Hepatology (Baltimore, Md.)","2018 Aug","Lebeaupin C, Vallee D, Rousseau D, Patouraux S, Bonnafous S, Adam G, Luciano F, Luci C, Anty R, Iannelli A, Marchetti S, Kroemer G, Lacas-Gervais S, Tran A, Gual P, Bailly-Maitre B"
8122a8932,8937
> "Q5RJI5-1","27251228","Structure and inhibition analysis of the mouse SAD-B C-terminal fragment.","Bioscience, biotechnology, and biochemistry","2016 Oct","Ma H, Wu JX, Wang J, Wang ZX, Wu JW"
> "Q5RJI5-1","27626661","SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression.","Cell reports","2016 Sep 13","Mochida S, Hida Y, Tanifuji S, Hagiwara A, Hamada S, Abe M, Ma H, Yasumura M, Kitajima I, Sakimura K, Ohtsuka T"
> "Q5RJI5-1","26444684","SAD-B kinase regulates pre-synaptic vesicular dynamics at hippocampal Schaffer collateral synapses and affects contextual fear memory.","Journal of neurochemistry","2016 Jan","Watabe AM, Nagase M, Hagiwara A, Hida Y, Tsuji M, Ochiai T, Kato F, Ohtsuka T"
> "Q5RJI5-1","17482548","LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.","Cell","2007 May 4","Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F"
> "Q5RJI5-1","15705853","Mammalian SAD kinases are required for neuronal polarization.","Science (New York, N.Y.)","2005 Feb 11","Kishi M, Pan YA, Crump JG, Sanes JR"
> "F2Z472-1","15582586","Functional preservation of duplicated pair for RSVS III gene in the REST locus of rat 3q42.","Biochemical and biophysical research communications","2005 Jan 14","Lin HJ, Lee CM, Luo CW, Chen YH"
8126,8128c8941,8943
< "Q06180-1","29712668","TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding.","Diabetes","2018 Jul","Dodd GT, Lee-Young RS, Bruning JC, Tiganis T"
< "Q06180-1","29444435","PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer.","Cell reports","2018 Feb 13","Spalinger MR, Manzini R, Hering L, Riggs JB, Gottier C, Lang S, Atrott K, Fettelschoss A, Olomski F, Kundig TM, Fried M, McCole DF, Rogler G, Scharl M"
< "Q06180-1","29587266","Overexpression of PTPN2 in Visceral Adipose Tissue Ameliorated Atherosclerosis via T Cells Polarization Shift in Diabetic Apoe-/- Mice.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2018","Li Y, Zhou H, Wang F, Han L, Liu M, Li Y, Wang Z, Tang M, Zhang W, Zhong M"
---
> "Q9EPU0-1","29959727","Dysregulated Up-Frameshift Protein 1 Promotes Ulcerative Colitis Pathogenesis Through the TNFR1-NF-kappaB/MAPKs Pathway.","Digestive diseases and sciences","2018 Oct","Zhu H, Huang S, Yue M, Chen W, Lu C, Lou X, Li C, Shan G, Chen H, Xu X, Xu G, Chen L"
> "Q9EPU0-1","28128343","RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.","Scientific reports","2017 Jan 27","Mooney CM, Jimenez-Mateos EM, Engel T, Mooney C, Diviney M, Veno MT, Kjems J, Farrell MA, O'Brien DF, Delanty N, Henshall DC"
> "Q9EPU0-1","27149095","Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.","PLoS genetics","2016 May","Fanourgakis G, Lesche M, Akpinar M, Dahl A, Jessberger R"
8130,8133d8944
< "Q4V9Z5-1","29979789","BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.","PloS one","2018","Causevic M, Dominko K, Malnar M, Vidatic L, Cermak S, Pigoni M, Kuhn PH, Colombo A, Havas D, Flunkert S, McDonald J, Gunnersen JM, Hutter-Paier B, Tahirovic S, Windisch M, Krainc D, Lichtenthaler SF, Hecimovic S"
< "Q4V9Z5-1","29032200","Sez6l2 regulates phosphorylation of ADD and neuritogenesis.","Biochemical and biophysical research communications","2017 Dec 9","Yaguchi H, Yabe I, Takahashi H, Watanabe M, Nomura T, Kano T, Matsumoto M, Nakayama KI, Watanabe M, Hatakeyama S"
< "Q4V9Z5-1","19242545","Association and mutation analyses of 16p11.2 autism candidate genes.","PloS one","2009","Kumar RA, Marshall CR, Badner JA, Babatz TD, Mukamel Z, Aldinger KA, Sudi J, Brune CW, Goh G, Karamohamed S, Sutcliffe JS, Cook EH, Geschwind DH, Dobyns WB, Scherer SW, Christian SL"
< "Q8BGR5-1","25183871","Simplet/Fam53b is required for Wnt signal transduction by regulating beta-catenin nuclear localization.","Development (Cambridge, England)","2014 Sep","Kizil C, Kuchler B, Yan JJ, Ozhan G, Moro E, Argenton F, Brand M, Weidinger G, Antos CL"
8143d8953
< "O88587-1","28801594","Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice.","Scientific reports","2017 Aug 11","Kanasaki M, Srivastava SP, Yang F, Xu L, Kudoh S, Kitada M, Ueki N, Kim H, Li J, Takeda S, Kanasaki K, Koya D"
8145c8955
< "Q99J78-1","10460589","Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system.","British journal of haematology","1999 Aug","Hotfilder M, Baxendale S, Cross MA, Sablitzky F"
---
> "P63015-1","16464444","Analysis of Pax6 expression using a BAC transgene reveals the presence of a paired-less isoform of Pax6 in the eye and olfactory bulb.","Developmental biology","2006 Apr 15","Kim J, Lauderdale JD"
8146a8957,8964
> "Q7TS63-1","27591365","Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.","Biochimica et biophysica acta","2016 Nov","Ishikura S, Tsunoda T, Nakabayashi K, Doi K, Koyanagi M, Hayashi K, Kawai T, Tanaka Y, Iwaihara Y, Luo H, Nishi K, Okamura T, Shirasawa S"
> "Q7TS63-1","27226588","The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway.","The Journal of biological chemistry","2016 Jul 15","Ishikura S, Iwaihara Y, Tanaka Y, Luo H, Nishi K, Doi K, Koyanagi M, Okamura T, Tsunoda T, Shirasawa S"
> "Q7TS63-1","26168481","Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells.","Anticancer research","2015 Aug","Iwaihara Y, Ishikura S, Doi K, Tsunoda T, Fujimoto T, Okamura T, Shirasawa S"
> "Q7TS63-1","21225468","ZFAT is a critical molecule for cell survival in mouse embryonic fibroblasts.","Cellular &amp; molecular biology letters","2011 Mar","Doi K, Fujimoto T, Koyanagi M, Tsunoda T, Tanaka Y, Yoshida Y, Takashima Y, Kuroki M, Sasazuki T, Shirasawa S"
> "Q7TS63-1","20660741","Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands.","Proceedings of the National Academy of Sciences of the United States of America","2010 Aug 10","Tsunoda T, Takashima Y, Tanaka Y, Fujimoto T, Doi K, Hirose Y, Koyanagi M, Yoshida Y, Okamura T, Kuroki M, Sasazuki T, Shirasawa S"
> "Q7TS63-1","18329245","ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes.","Genomics","2008 May","Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S"
> "Q9JIY2-1","19535458","Novel roles of hakai in cell proliferation and oncogenesis.","Molecular biology of the cell","2009 Aug","Figueroa A, Kotani H, Toda Y, Mazan-Mamczarz K, Mueller EC, Otto A, Disch L, Norman M, Ramdasi RM, Keshtgar M, Gorospe M, Fujita Y"
> "Q9JIY2-1","12165405","Alteration of E-cadherin and beta-catenin in mouse vestibular epithelia during induction of apoptosis.","Neuroscience letters","2002 Aug 30","Kim TS, Nakagawa T, Endo T, Iguchi F, Murai N, Naito Y, Ito J"
8172a8991
> "Q6P8X9-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
8187,8189d9005
< "Q5VCS6-1","29317670","TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice.","Nature communications","2018 Jan 9","Ding D, Liu J, Midic U, Wu Y, Dong K, Melnick A, Latham KE, Chen C"
< "Q5VCS6-1","21383078","TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.","The Journal of cell biology","2011 Mar 7","Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M"
< "Q5VCS6-1","15465492","Expression of the tudor-related gene Tdrd5 during development of the male germline in mice.","Gene expression patterns : GEP","2004 Oct","Smith JM, Bowles J, Wilson M, Teasdale RD, Koopman P"
8198,8202c9014,9020
< "Q8R0Z2-1","21625959","hnRNP F directs formation of an exon 4 minus variant of tumor-associated NADH oxidase (ENOX2).","Molecular and cellular biochemistry","2011 Nov","Tang X, Kane VD, Morre DM, Morre DJ"
< "Q8R0Z2-1","18980249","Cell size increased in tissues from transgenic mice overexpressing a cell surface growth-related and cancer-specific hydroquinone oxidase, tNOX, with protein disulfide-thiol interchange activity.","Journal of cellular biochemistry","2008 Dec 15","Yagiz K, Snyder PW, Morre DJ, Morre DM"
< "Q8R0Z2-1","17115410","Mouse embryonic fibroblast cells from transgenic mice overexpressing tNOX exhibit an altered growth and drug response phenotype.","Journal of cellular biochemistry","2007 May 15","Yagiz K, Wu LY, Kuntz CP, James Morre D, Morre DM"
< "Q8BWL5-1","22372950","Rbms3, an RNA-binding protein, mediates the expression of Ptf1a by binding to its 3'UTR during mouse pancreas development.","DNA and cell biology","2012 Jul","Lu CK, Lai YC, Chen HR, Chiang MK"
< "A2ABV5-1","20194623","MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.","Molecular and cellular biology","2010 May","Grontved L, Madsen MS, Boergesen M, Roeder RG, Mandrup S"
---
> "Q9WVQ1-1","28539383","Glomerulosclerosis Induced by Deficiency of Membrane-Associated Guanylate Kinase Inverted 2 in Kidney Podocytes.","Journal of the American Society of Nephrology : JASN","2017 Sep","Shirata N, Ihara KI, Yamamoto-Nonaka K, Seki T, Makino SI, Oliva Trejo JA, Miyake T, Yamada H, Campbell KN, Nakagawa T, Mori K, Yanagita M, Mundel P, Nishimori K, Asanuma K"
> "Q9WVQ1-1","25993318","Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.","Kidney international","2015 Aug","Lefebvre J, Clarkson M, Massa F, Bradford ST, Charlet A, Buske F, Lacas-Gervais S, Schulz H, Gimpel C, Hata Y, Schaefer F, Schedl A"
> "Q9WVQ1-1","25653350","S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model.","The Journal of neuroscience : the official journal of the Society for Neuroscience","2015 Feb 4","Zhang N, Zhong P, Shin SM, Metallo J, Danielson E, Olsen CM, Liu QS, Lee SH"
> "Q9WVQ1-1","25271328","MAGI-2 scaffold protein is critical for kidney barrier function.","Proceedings of the National Academy of Sciences of the United States of America","2014 Oct 14","Balbas MD, Burgess MR, Murali R, Wongvipat J, Skaggs BJ, Mundel P, Weins A, Sawyers CL"
> "Q9WVQ1-1","14750953","Nectin-dependent localization of synaptic scaffolding molecule (S-SCAM) at the puncta adherentia junctions formed between the mossy fibre terminals and the dendrites of pyramidal cells in the CA3 area of the mouse hippocampus.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2003 Dec","Yamada A, Irie K, Deguchi-Tawarada M, Ohtsuka T, Takai Y"
> "Q5NCY0-1","18003914","Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.","Proceedings of the National Academy of Sciences of the United States of America","2007 Nov 20","Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K"
> "Q5NCY0-1","17825402","The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing.","Cell","2007 Sep 21","De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G"
8204,8211d9021
< "Q9D2A5-1","28778797","Tisp40 deficiency attenuates renal ischemia reperfusion injury induced apoptosis of tubular epithelial cells.","Experimental cell research","2017 Oct 1","Qin C, Xiao C, Su Y, Zheng H, Xu T, Lu J, Luo P, Zhang J"
< "Q9D2A5-1","28618421","Identification of Tisp40 as an Essential Regulator of Renal Tubulointerstitial Fibrosis via TGF-beta/Smads Pathway.","Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology","2017","Xiao CC, Zhang J, Luo PC, Qin C, Du Y, Ning JZ, Zheng HZ"
< "Q9D2A5-1","25412305","Identification of Creb3l4 as an essential negative regulator of adipogenesis.","Cell death &amp; disease","2014 Nov 20","Kim TH, Jo SH, Choi H, Park JM, Kim MY, Nojima H, Kim JW, Ahn YH"
< "Q9D2A5-1","16925989","The enigma of ATCE1, an acrosome-associated transcription factor.","Developmental biology","2006 Oct 1","Gil S, Yosef D, Golan N, Don J"
< "Q9D2A5-1","16728718","Stage-specific expression of the Atce1/Tisp40alpha isoform of CREB3L4 in mouse spermatids.","Journal of andrology","2006 Sep-Oct","El-Alfy M, Azzi L, Lessard J, Lavergne E, Pelletier M, Labrie C"
< "Q9D2A5-1","16595651","Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.","The Journal of biological chemistry","2006 Jun 2","Nagamori I, Yomogida K, Adams PD, Sassone-Corsi P, Nojima H"
< "Q9D2A5-1","16107712","Reduction of spermatogenesis but not fertility in Creb3l4-deficient mice.","Molecular and cellular biology","2005 Sep","Adham IM, Eck TJ, Mierau K, Muller N, Sallam MA, Paprotta I, Schubert S, Hoyer-Fender S, Engel W"
< "Q9D2A5-1","15938716","Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway.","Genes to cells : devoted to molecular &amp; cellular mechanisms","2005 Jun","Nagamori I, Yabuta N, Fujii T, Tanaka H, Yomogida K, Nishimune Y, Nojima H"
8214,8215d9023
< "Q9JLB9-1","28872640","Nectin-3 modulates the structural plasticity of dentate granule cells and long-term memory.","Translational psychiatry","2017 Sep 5","Wang XX, Li JT, Xie XM, Gu Y, Si TM, Schmidt MV, Wang XD"
< "Q9JLB9-1","12121624","Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.","Current biology : CB","2002 Jul 9","Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y"
8216a9025
> "Q9JMB1-1","12748127","Male mice lacking the Theg (testicular haploid expressed gene) protein undergo normal spermatogenesis and are fertile.","Biology of reproduction","2003 Sep","Mannan AU, Nayernia K, Mueller C, Burfeind P, Adham IM, Engel W"
8218a9028,9029
> "Q8C0V0-1","28708136","Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.","Cell death and differentiation","2017 Nov","Segura-Bayona S, Knobel PA, Gonzalez-Buron H, Youssef SA, Pena-Blanco A, Coyaud E, Lopez-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH"
> "Q9D1H0-1","28487372","Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.","The Journal of biological chemistry","2017 Jun 23","Tabaja N, Yuan Z, Oswald F, Kovall RA"
8221a9033,9035
> "E9Q616-1","21940993","Self-regulated alternative splicing at the AHNAK locus.","FASEB journal : official publication of the Federation of American Societies for Experimental Biology","2012 Jan","de Morree A, Droog M, Grand Moursel L, Bisschop IJ, Impagliazzo A, Frants RR, Klooster R, van der Maarel SM"
> "Q9JLB9-1","28872640","Nectin-3 modulates the structural plasticity of dentate granule cells and long-term memory.","Translational psychiatry","2017 Sep 5","Wang XX, Li JT, Xie XM, Gu Y, Si TM, Schmidt MV, Wang XD"
> "Q9JLB9-1","12121624","Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.","Current biology : CB","2002 Jul 9","Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y"
8226a9041,9042
> "Q8BP97-1","24859449","Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.","Nature immunology","2014 Jul","Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, Zhang T, Ma F, Wang Q, Wang J, Deng K, Zhuang Y, Wu X, Yu Y, Xu T, Cao X"
> "Q8BP97-1","23610400","Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation.","Proceedings of the National Academy of Sciences of the United States of America","2013 May 7","Liu J, Liu S, Xia M, Xu S, Wang C, Bao Y, Jiang M, Wu Y, Xu T, Cao X"
8232,8235c9048
< "Q8CE08-1","27783536","Prostatic Acid Phosphatase Alters the RANKL/OPG System and Induces Osteoblastic Prostate Cancer Bone Metastases.","Endocrinology","2016 Dec","Kirschenbaum A, Izadmehr S, Yao S, O'Connor-Chapman KL, Huang A, Gregoriades EM, Yakar S, Levine AC"
< "Q8CE08-1","27348306","Expression of Prostatic Acid Phosphatase in Rat Circumvallate Papillae.","PloS one","2016","Nishida K, Kubota T, Matsumoto S, Kato J, Watanabe Y, Yamamoto A, Furui M, Ohishi A, Nagasawa K"
< "Q8CE08-1","27306411","EXPRESS: NGF-trkA signaling modulates the analgesic effects of prostatic acid phosphatase in resiniferatoxin-induced neuropathy.","Molecular pain","2016","Wu CH, Ho WY, Lee YC, Lin CL, Hsieh YL"
< "Q8CE08-1","19158948","Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception.","PloS one","2009","Sowa NA, Vadakkan KI, Zylka MJ"
---
> "P54830-1","29508281","Altered Intracellular Calcium Homeostasis Underlying Enhanced Glutamatergic Transmission in Striatal-Enriched Tyrosine Phosphatase (STEP) Knockout Mice.","Molecular neurobiology","2018 Oct","Bosco F, Valente P, Milanese M, Piccini A, Messa M, Bonanno G, Lombroso P, Baldelli P, Benfenati F, Giovedi S"
8237,8240d9049
< "Q3U8K7-1","27920088","SUV4-20 activity in the preimplantation mouse embryo controls timely replication.","Genes &amp; development","2016 Nov 15","Eid A, Rodriguez-Terrones D, Burton A, Torres-Padilla ME"
< "Q3U8K7-1","26669898","Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation.","Cell stem cell","2016 Feb 4","Boonsanay V, Zhang T, Georgieva A, Kostin S, Qi H, Yuan X, Zhou Y, Braun T"
< "Q3U8K7-1","23720823","FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.","Journal of molecular cell biology","2013 Oct","Neguembor MV, Xynos A, Onorati MC, Caccia R, Bortolanza S, Godio C, Pistoni M, Corona DF, Schotta G, Gabellini D"
< "Q3U8K7-1","17846168","Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.","The Journal of cell biology","2007 Sep 10","Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA"
8249a9059,9063
> "A2AP18-1","23237262","Phospholipase C-eta2 is required for retinoic acid-stimulated neurite growth.","Journal of neurochemistry","2013 Mar","Popovics P, Gray A, Arastoo M, Finelli DK, Tan AJ, Stewart AJ"
> "A2AP18-1","20060933","Phospholipase C-eta2 is highly expressed in the habenula and retina.","Gene expression patterns : GEP","2010 Feb-Mar","Kanemaru K, Nakahara M, Nakamura Y, Hashiguchi Y, Kouchi Z, Yamaguchi H, Oshima N, Kiyonari H, Fukami K"
> "A2AP18-1","16107206","Molecular cloning and characterization of PLC-eta2.","The Biochemical journal","2005 Nov 1","Zhou Y, Wing MR, Sondek J, Harden TK"
> "A2AP18-1","15899900","A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme.","The Journal of biological chemistry","2005 Aug 12","Nakahara M, Shimozawa M, Nakamura Y, Irino Y, Morita M, Kudo Y, Fukami K"
> "A2AP18-1","15583837","Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes.","International journal of molecular medicine","2005 Jan","Stewart AJ, Mukherjee J, Roberts SJ, Lester D, Farquharson C"
8259a9074,9075
> "Q921U8-1","18678771","Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice.","Circulation","2008 Aug 19","Rensen SS, Niessen PM, van Deursen JM, Janssen BJ, Heijman E, Hermeling E, Meens M, Lie N, Gijbels MJ, Strijkers GJ, Doevendans PA, Hofker MH, De Mey JG, van Eys GJ"
> "Q921U8-1","16285958","Smoothelin-a is essential for functional intestinal smooth muscle contractility in mice.","Gastroenterology","2005 Nov","Niessen P, Rensen S, van Deursen J, De Man J, De Laet A, Vanderwinden JM, Wedel T, Baker D, Doevendans P, Hofker M, Gijbels M, van Eys G"
8260a9077,9080
> "Q6P8Y7-1","24914955","SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cells.","PloS one","2014","Vieira N, Deng FM, Liang FX, Liao Y, Chang J, Zhou G, Zheng W, Simon JP, Ding M, Wu XR, Romih R, Kreibich G, Sun TT"
> "P97438-1","28839101","Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins.","American journal of physiology. Lung cellular and molecular physiology","2017 Dec 1","Schwingshackl A, Lopez B, Teng B, Luellen C, Lesage F, Belperio J, Olcese R, Waters CM"
> "P97438-1","29042297","TREK-1 pathway mediates isoflurane-induced memory impairment in middle-aged mice.","Neurobiology of learning and memory","2017 Nov","Cai Y, Peng Z, Guo H, Wang F, Zeng Y"
> "P09925-1","26804654","Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects.","Biochimica et biophysica acta","2016 Apr","Kovarova N, Pecina P, Nuskova H, Vrbacky M, Zeviani M, Mracek T, Viscomi C, Houstek J"
8267d9086
< "Q9QWT9-1","23807208","The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis.","Cellular and molecular life sciences : CMLS","2014 Feb","Kypri E, Christodoulou A, Maimaris G, Lethan M, Markaki M, Lysandrou C, Lederer CW, Tavernarakis N, Geimer S, Pedersen LB, Santama N"
8268a9088,9089
> "P42682-1","26466958","A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.","Journal of immunology (Baltimore, Md. : 1950)","2015 Nov 15","Cho HS, Shin HM, Haberstock-Debic H, Xing Y, Owens TD, Funk JO, Hill RJ, Bradshaw JM, Berg LJ"
> "P42682-1","22403441","A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice.","Journal of immunology (Baltimore, Md. : 1950)","2012 Apr 15","Qi Q, Huang W, Bai Y, Balmus G, Weiss RS, August A"
8270,8271d9090
< "Q811D0-1","29995933","SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus.","PloS one","2018","Gupta P, Uner OE, Nayak S, Grant GR, Kalb RG"
< "Q811D0-1","28103480","Adrenergic Gate Release for Spike Timing-Dependent Synaptic Potentiation.","Neuron","2017 Jan 18","Liu Y, Cui L, Schwarz MK, Dong Y, Schluter OM"
8272a9092,9095
> "Q0QWG9-1","18509461","Enhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilin.","PloS one","2008 May 28","Takeuchi T, Ohtsuki G, Yoshida T, Fukaya M, Wainai T, Yamashita M, Yamazaki Y, Mori H, Sakimura K, Kawamoto S, Watanabe M, Hirano T, Mishina M"
> "Q0QWG9-1","16168524","Identification and characterization of a novel Delphilin variant with an alternative N-terminus.","Brain research. Molecular brain research","2005 Nov 18","Yamashita T, Miyagi Y, Ono M, Ito H, Watanabe K, Sonoda T, Tsuzuki K, Ozawa S, Aoki I, Okuda K, Mishina M, Kawamoto S"
> "Q0QWG9-1","12628171","Lurcher GRID2-induced death and depolarization can be dissociated in cerebellar Purkinje cells.","Neuron","2003 Mar 6","Selimi F, Lohof AM, Heitz S, Lalouette A, Jarvis CI, Bailly Y, Mariani J"
> "Q0QWG9-1","12372286","A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.","Neuron","2002 Aug 29","Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N"
8274,8276c9097
< "O35453-1","12962630","The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain.","Structure (London, England : 1993)","2003 Sep","Somoza JR, Ho JD, Luong C, Ghate M, Sprengeler PA, Mortara K, Shrader WD, Sperandio D, Chan H, McGrath ME, Katz BA"
< "Q9QWZ1-1","23468651","Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.","PLoS genetics","2013","Lyndaker AM, Lim PX, Mleczko JM, Diggins CE, Holloway JK, Holmes RJ, Kan R, Schlafer DH, Freire R, Cohen PE, Weiss RS"
< "Q9QWZ1-1","21637962","Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses.","Protein &amp; cell","2011 May","Zhang C, Liu Y, Hu Z, An L, He Y, Hang H"
---
> "Q9WVA3-1","27177335","Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes.","Oncotarget","2016 May 24","Dai XX, Xiong H, Zhang M, Sun S, Xiong B"
8288,8290d9108
< "P60670-1","26112410","The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-kappaB Signaling via Partial Degradation of the NF-kappaB Subunit p100.","The Journal of biological chemistry","2015 Aug 7","Zhang Z, Wang Y, Li C, Shi Z, Hao Q, Wang W, Song X, Zhao Y, Jiao S, Zhou Z"
< "P60670-1","17491009","Detailed structural insights into the p97-Npl4-Ufd1 interface.","The Journal of biological chemistry","2007 Jul 20","Isaacson RL, Pye VE, Simpson P, Meyer HH, Zhang X, Freemont PS, Matthews S"
< "P60670-1","16103111","Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors.","The Journal of biological chemistry","2005 Oct 14","Alzayady KJ, Panning MM, Kelley GG, Wojcikiewicz RJ"
8300a9119
> "Q9Z218-1","23912628","DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development.","Nature communications","2013","Lin L, Sun W, Throesch B, Kung F, Decoster JT, Berner CJ, Cheney RE, Rudy B, Hoffman DA"
8309a9129,9131
> "Q9ESU6-1","29662175","Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.","Nature cell biology","2018 May","Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB"
> "Q9ESU6-1","12192049","A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase.","Molecular and cellular biology","2002 Sep","Maruyama T, Farina A, Dey A, Cheong J, Bermudez VP, Tamura T, Sciortino S, Shuman J, Hurwitz J, Ozato K"
> "Q9ESU6-1","11997514","Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.","Molecular and cellular biology","2002 Jun","Houzelstein D, Bullock SL, Lynch DE, Grigorieva EF, Wilson VA, Beddington RS"
8326a9149
> "Q61532-1","12808096","Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation.","Molecular and cellular biology","2003 Jul","Coulombe P, Rodier G, Pelletier S, Pellerin J, Meloche S"
8330,8332d9152
< "Q9D6X5-1","27272163","Disruption of Slc52a3 gene causes neonatal lethality with riboflavin deficiency in mice.","Scientific reports","2016 Jun 8","Yoshimatsu H, Yonezawa A, Yamanishi K, Yao Y, Sugano K, Nakagawa S, Imai S, Omura T, Nakagawa T, Yano I, Masuda S, Inui K, Matsubara K"
< "Q9D6X5-1","26976849","SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.","Human molecular genetics","2016 May 1","Intoh A, Suzuki N, Koszka K, Eggan K"
< "Q9D6X5-1","26660539","Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption.","American journal of physiology. Gastrointestinal and liver physiology","2016 Feb 15","Subramanian VS, Lambrecht N, Lytle C, Said HM"
8334,8337c9154,9160
< "Q9CZ44-1","27540115","Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype.","Proceedings of the National Academy of Sciences of the United States of America","2016 Sep 6","Al Ghouleh I, Meijles DN, Mutchler S, Zhang Q, Sahoo S, Gorelova A, Henrich Amaral J, Rodriguez AI, Mamonova T, Song GJ, Bisello A, Friedman PA, Cifuentes-Pagano ME, Pagano PJ"
< "Q9CZ44-1","23429921","NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.","Diabetologia","2013 May","Koulajian K, Desai T, Liu GC, Ivovic A, Patterson JN, Tang C, El-Benna J, Joseph JW, Scholey JW, Giacca A"
< "Q9CZ44-1","18403597","Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.","The American journal of pathology","2008 May","Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, Caito S, Adenuga D, Rahman I"
< "Q9CZ44-1","14988733","Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.","The EMBO journal","2004 Mar 10","Dreveny I, Kondo H, Uchiyama K, Shaw A, Zhang X, Freemont PS"
---
> "B2RXV4-1","27006955","TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages.","Journal of immunology research","2016","Philip M, Chiu EY, Hajjar AM, Abkowitz JL"
> "B2RXV4-1","26067085","Crucial Role of FLVCR1a in the Maintenance of Intestinal Heme Homeostasis.","Antioxidants &amp; redox signaling","2015 Dec 20","Fiorito V, Forni M, Silengo L, Altruda F, Tolosano E"
> "B2RXV4-1","25582857","Heme exporter FLVCR is required for T cell development and peripheral survival.","Journal of immunology (Baltimore, Md. : 1950)","2015 Feb 15","Philip M, Funkhouser SA, Chiu EY, Phelps SR, Delrow JJ, Cox J, Fink PJ, Abkowitz JL"
> "B2RXV4-1","24486949","Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.","Gastroenterology","2014 May","Vinchi F, Ingoglia G, Chiabrando D, Mercurio S, Turco E, Silengo L, Altruda F, Tolosano E"
> "B2RXV4-1","24021674","FLVCR is necessary for erythroid maturation, may contribute to platelet maturation, but is dispensable for normal hematopoietic stem cell function.","Blood","2013 Oct 17","Byon JC, Chen J, Doty RT, Abkowitz JL"
> "B2RXV4-1","22058337","Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis.","Investigative ophthalmology &amp; visual science","2011 Nov 29","Gnana-Prakasam JP, Reddy SK, Veeranan-Karmegam R, Smith SB, Martin PM, Ganapathy V"
> "B2RXV4-1","18258918","A heme export protein is required for red blood cell differentiation and iron homeostasis.","Science (New York, N.Y.)","2008 Feb 8","Keel SB, Doty RT, Yang Z, Quigley JG, Chen J, Knoblaugh S, Kingsley PD, De Domenico I, Vaughn MB, Kaplan J, Palis J, Abkowitz JL"
8342a9166
> "O35680-1","19439209","NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells.","Biochimica et biophysica acta","2009 May","Zanotto E, Hakkinen A, Teku G, Shen B, Ribeiro AS, Jacobs HT"
8346,8349c9170,9174
< "Q8K4J0-1","25818648","Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.","Molecular cell","2015 Apr 2","Jiang W, Crowe JL, Liu X, Nakajima S, Wang Y, Li C, Lee BJ, Dubois RL, Liu C, Yu X, Lan L, Zha S"
< "Q8K4J0-1","12615897","Defective DNA repair and increased genomic instability in Artemis-deficient murine cells.","The Journal of experimental medicine","2003 Mar 3","Rooney S, Alt FW, Lombard D, Whitlow S, Eckersdorff M, Fleming J, Fugmann S, Ferguson DO, Schatz DG, Sekiguchi J"
< "Q8K4J0-1","12504013","Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice.","Molecular cell","2002 Dec","Rooney S, Sekiguchi J, Zhu C, Cheng HL, Manis J, Whitlow S, DeVido J, Foy D, Chaudhuri J, Lombard D, Alt FW"
< "Q9ET47-1","28516904","Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin.","Nature communications","2017 May 18","Lui NC, Tam WY, Gao C, Huang JD, Wang CC, Jiang L, Yung WH, Kwan KM"
---
> "Q60520-2","29494759","Transcriptional co-repressor SIN3A silencing rescues decline in memory consolidation during scopolamine-induced amnesia.","Journal of neurochemistry","2018 May","Srivas S, Thakur MK"
> "Q8VE91-4","27511895","FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga.","The Journal of infectious diseases","2016 Oct 15","Chiramel AI, Dougherty JD, Nair V, Robertson SJ, Best SM"
> "Q8VE91-4","26040720","Regulation of endoplasmic reticulum turnover by selective autophagy.","Nature","2015 Jun 18","Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, Kurth I, Hubner CA, Dikic I"
> "Q8VE91-4","19838196","Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy.","Nature genetics","2009 Nov","Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nurnberg G, Nurnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hubner CA"
> "O35309-1","29038465","NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.","Nature communications","2017 Oct 16","Xiahou Z, Wang X, Shen J, Zhu X, Xu F, Hu R, Guo D, Li H, Tian Y, Liu Y, Liang H"
8353,8354c9178
< "Q6NWV3-1","30476139","C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization.","Journal of biochemistry","2019 Mar 1","Takahara M, Kunii M, Nakamura K, Harada A, Hirano T, Katoh Y, Nakayama K"
< "Q6NWV3-1","19000668","Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.","Developmental biology","2009 Jan 1","Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A"
---
> "Q8BSN9-1","20869947","Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration.","Biochemical and biophysical research communications","2010 Oct 22","Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro JB, Adelmant GO, Marto JA, Rhee K, Tisdale S, Danial N, Benarafa C, Orduna A, Anderson P"
8357,8359c9181
< "Q9D032-1","27236334","Single-stranded DNA binding protein Ssbp3 induces differentiation of mouse embryonic stem cells into trophoblast-like cells.","Stem cell research &amp; therapy","2016 May 28","Liu J, Luo X, Xu Y, Gu J, Tang F, Jin Y, Li H"
< "Q9D032-1","26495868","SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic beta-Cell Target Genes.","Molecular endocrinology (Baltimore, Md.)","2015 Dec","Galloway JR, Bethea M, Liu Y, Underwood R, Mobley JA, Hunter CS"
< "Q9D032-1","15857913","Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.","Development (Cambridge, England)","2005 Jun","Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H"
---
> "Q7TSV9-1","17971504","Tissue expression patterns identify mouse cilia genes.","Physiological genomics","2008 Jan 17","McClintock TS, Glasser CE, Bose SC, Bergman DA"
8363,8366d9184
< "Q8BW72-1","29054488","The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice.","Experimental cell research","2017 Dec 1","Zhou J, Wang F, Xu C, Zhou Z, Zhang W"
< "Q8BW72-1","28827393","Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.","Development (Cambridge, England)","2017 Sep 15","Sankar A, Kooistra SM, Gonzalez JM, Ohlsson C, Poutanen M, Helin K"
< "Q8BW72-1","28511912","Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction.","Clinical immunology (Orlando, Fla.)","2017 Jul","Ishiguro K, Watanabe O, Nakamura M, Yamamura T, Matsushita M, Goto H, Hirooka Y"
< "Q8BW72-1","27711046","Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression.","Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology","2017 Mar","Pathak SS, Maitra S, Chakravarty S, Kumar A"
8368a9187,9189
> "P97376-1","23720823","FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.","Journal of molecular cell biology","2013 Oct","Neguembor MV, Xynos A, Onorati MC, Caccia R, Bortolanza S, Godio C, Pistoni M, Corona DF, Schotta G, Gabellini D"
> "Q3U285-1","25366156","Splicing variants of NOL4 differentially regulate the transcription activity of Mlr1 and Mlr2 in cultured cells.","Zoological science","2014 Nov","Takayanagi-Kiya S, Misawa-Hojo K, Kiya T, Kunieda T, Kubo T"
> "Q3U285-1","12560079","Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1).","FEBS letters","2003 Jan 30","Kunieda T, Park JM, Takeuchi H, Kubo T"
8376,8378c9197,9199
< "Q9QYS9-1","30628007","Identification of Novel Binding Partners for Transcription Factor Emx2.","The protein journal","2019 Feb","Groves JA, Gillman C, DeLay CN, Kroll TT"
< "Q9QYS9-1","29021242","Autogenous cross-regulation of Quaking mRNA processing and translation balances Quaking functions in splicing and translation.","Genes &amp; development","2017 Sep 15","Fagg WS, Liu N, Fair JH, Shiue L, Katzman S, Donohue JP, Ares M Jr"
< "Q9QYS9-1","29021239","An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling.","Genes &amp; development","2017 Sep 15","Hayakawa-Yano Y, Suyama S, Nogami M, Yugami M, Koya I, Furukawa T, Zhou L, Abe M, Sakimura K, Takebayashi H, Nakanishi A, Okano H, Yano M"
---
> "P11438-1","29860631","A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss.","Human genetics","2018 Jul","Wang L, Feng Y, Yan D, Qin L, Grati M, Mittal R, Li T, Sundhari AK, Liu Y, Chapagain P, Blanton SH, Liao S, Liu X"
> "P11438-1","29749495","LIN28A inhibits lysosomeassociated membrane glycoprotein 1 protein expression in embryonic stem and bladder cancer cells.","Molecular medicine reports","2018 Jul","Pan P, Chen T, Zhang Y, Qi Z, Qin J, Cui G, Guo X"
> "P11438-1","30068868","The Major Lysosomal Membrane Proteins LAMP-1 and LAMP-2 Participate in Differentiation of C2C12 Myoblasts.","Biological &amp; pharmaceutical bulletin","2018","Sakane H, Akasaki K"