{ "bcoid": "GLY_000597", "title": "Human UniProtKB Xref Rhea", "description": "The Human UniProtKB Xref Rhea contains human [taxid:9606] UniProtKB canonical accessions cross-referenced ...", "filename": "human_protein_xref_rhea.csv", "filetype": "csv", "categories": { "species": "Homo sapiens", "molecule": "Protein", "tags": "Rhea cross-references", "file_type": "csv", "status": "Reviewed", "scope": "internal" }, "minitable": { "content": [ [ "P30613-1...", "protein_xref..." ], [ "Q96J66-1...", "protein_xref..." ] ], "headers": [ "uniprotkb_ca...", "xref_key..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "xref_label" } ], [ "P30613-1", "protein_xref_rhea", "18157", "ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate" ], [ "Q96J66-1", "protein_xref_rhea", "61348", "ATP + estrone 3-sulfate(in) + H2O = ADP + estrone 3-sulfate(out) + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "19121", "an S-substituted glutathione(in) + ATP + H2O = ADP + an S-substituted glutathione(out) + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "50056", "ATP + glycocholate(in) + H2O = ADP + glycocholate(out) + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "38963", "ATP + H2O + leukotriene C4(in) = ADP + H(+) + leukotriene C4(out) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "50052", "ATP + H2O + taurocholate(in) = ADP + H(+) + phosphate + taurocholate(out)" ], [ "Q96J66-1", "protein_xref_rhea", "60128", "17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ATP + H2O = 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ADP + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "61364", "3beta-sulfooxy-androst-5-en-17-one(in) + ATP + H2O = 3beta-sulfooxy-androst-5-en-17-one(out) + ADP + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "66188", "3',5'-cyclic GMP(in) + ATP + H2O = 3',5'-cyclic GMP(out) + ADP + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "66184", "3',5'-cyclic AMP(in) + ATP + H2O = 3',5'-cyclic AMP(out) + ADP + H(+) + phosphate" ], [ "Q96J66-1", "protein_xref_rhea", "61380", "2,4-dinitrophenyl-S-glutathione(in) + ATP + H2O = 2,4-dinitrophenyl-S-glutathione(out) + ADP + H(+) + phosphate" ], [ "Q969W1-1", "protein_xref_rhea", "36683", "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]" ], [ "P41250-1", "protein_xref_rhea", "16013", "ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)" ], [ "P41250-1", "protein_xref_rhea", "34935", "2 ATP + H(+) = diphosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate" ], [ "Q01813-1", "protein_xref_rhea", "16109", "ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)" ], [ "Q9UHL0-1", "protein_xref_rhea", "13065", "ATP + H2O = ADP + H(+) + phosphate" ], [ "Q9Y295-1", "protein_xref_rhea", "19669", "GTP + H2O = GDP + H(+) + phosphate" ], [ "Q9BVK2-1", "protein_xref_rhea", "31307", "alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + dolichyl beta-D-glucosyl phosphate = alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + dolichyl phosphate + H(+)" ], [ "Q8IYD8-1", "protein_xref_rhea", "13065", "ATP + H2O = ADP + H(+) + phosphate" ], [ "P24903-1", "protein_xref_rhea", "17149", "an organic molecule + O2 + reduced [NADPH--hemoprotein reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]" ], [ "Q15831-1", "protein_xref_rhea", "17989", "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]" ], [ "Q15831-1", "protein_xref_rhea", "46608", "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]" ], [ "O95342-1", "protein_xref_rhea", "50052", "ATP + H2O + taurocholate(in) = ADP + H(+) + phosphate + taurocholate(out)" ], [ "O95342-1", "protein_xref_rhea", "50060", "ATP + glycochenodeoxycholate(in) + H2O = ADP + glycochenodeoxycholate(out) + H(+) + phosphate" ], [ "O95342-1", "protein_xref_rhea", "50068", "ATP + glycoursodeoxycholate(in) + H2O = ADP + glycoursodeoxycholate(out) + H(+) + phosphate" ], [ "O95342-1", "protein_xref_rhea", "63908", "ATP + H2O + pravastatin(in) = ADP + H(+) + phosphate + pravastatin(out)" ], [ "O95342-1", "protein_xref_rhea", "50072", "ATP + H2O + tauroursodeoxycholate(in) = ADP + H(+) + phosphate + tauroursodeoxycholate(out)" ], [ "O95342-1", "protein_xref_rhea", "50064", "ATP + H2O + taurochenodeoxycholate(in) = ADP + H(+) + phosphate + taurochenodeoxycholate(out)" ], [ "O95342-1", "protein_xref_rhea", "50056", "ATP + glycocholate(in) + H2O = ADP + glycocholate(out) + H(+) + phosphate" ], [ "O95342-1", "protein_xref_rhea", "50048", "ATP + cholate(in) + H2O = ADP + cholate(out) + H(+) + phosphate" ], [ "O60507-1", "protein_xref_rhea", "16801", "3'-phosphoadenylyl sulfate + L-tyrosyl-[protein] = adenosine 3',5'-bisphosphate + H(+) + O-sulfo-L-tyrosine-[protein]" ], [ "Q9NV23-1", "protein_xref_rhea", "40119", "H2O + tetradecanoyl-CoA = CoA + H(+) + tetradecanoate" ], [ "Q9NV23-1", "protein_xref_rhea", "16645", "H2O + hexadecanoyl-CoA = CoA + H(+) + hexadecanoate" ], [ "Q9NV23-1", "protein_xref_rhea", "40059", "decanoyl-CoA + H2O = CoA + decanoate + H(+)" ], [ "Q9NV23-1", "protein_xref_rhea", "30135", "dodecanoyl-CoA + H2O = CoA + dodecanoate + H(+)" ], [ "Q9NV23-1", "protein_xref_rhea", "15057", "(9Z)-octadecenoyl-[ACP] + H2O = (9Z)-octadecenoate + H(+) + holo-[ACP]" ], [ "P45984-1", "protein_xref_rhea", "46608", "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]" ], [ "P45984-1", "protein_xref_rhea", "17989", "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]" ], [ "Q9UEF7-1", "protein_xref_rhea", "17633", "a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate" ], [ "Q9H237-1", "protein_xref_rhea", "45336", "(9Z)-hexadecenoyl-CoA + [Wnt protein]-L-serine = [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + CoA" ], [ "O60832-1", "protein_xref_rhea", "47036", "uridine in 5S rRNA = pseudouridine in 5S rRNA" ], [ "P48506-1", "protein_xref_rhea", "13285", "ATP + L-cysteine + L-glutamate = ADP + H(+) + L-gamma-glutamyl-L-cysteine + phosphate" ], [ "P17900-1", "protein_xref_rhea", "39747", "cholesterol(in) = cholesterol(out)" ], [ "Q9NPI5-1", "protein_xref_rhea", "25568", "ATP + beta-D-ribosylnicotinate = ADP + H(+) + nicotinate beta-D-ribonucleotide" ], [ "Q9NPI5-1", "protein_xref_rhea", "14017", "ATP + beta-nicotinamide D-riboside = ADP + beta-nicotinamide D-ribonucleotide + H(+)" ], [ "Q9NPI6-1", "protein_xref_rhea", "67484", "a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GDP" ], [ "Q05397-1", "protein_xref_rhea", "10596", "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]" ], [ "Q96LT4-1", "protein_xref_rhea", "42128", "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-hexadecanoylsphinganine = a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-sphinganine-1-phosphoethanolamine" ], [ "Q96LT4-1", "protein_xref_rhea", "42144", "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-hexadecanoyl-(4R)-hydroxysphinganine = a 1,2-diacyl-sn-glycerol + N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine" ], [ "Q9NY93-1", "protein_xref_rhea", "13065", "ATP + H2O = ADP + H(+) + phosphate" ], [ "Q9H4B8-1", "protein_xref_rhea", "48940", "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid" ], [ "Q96AQ7-1", "protein_xref_rhea", "39011", "a triacyl-sn-glycerol(in) = a triacyl-sn-glycerol(out)" ], [ "Q6P1M0-1", "protein_xref_rhea", "38879", "a fatty acid(in) = a fatty acid(out)" ], [ "Q6P1M0-1", "protein_xref_rhea", "19713", "(5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate" ], [ "Q6P1M0-1", "protein_xref_rhea", "45264", "(9Z,12Z)-octadecadienoate(out) = (9Z,12Z)-octadecadienoate(in)" ], [ "Q6P1M0-1", "protein_xref_rhea", "33607", "(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate" ], [ "Q6P1M0-1", "protein_xref_rhea", "36139", "(E)-hexadec-2-enoate + ATP + CoA = (2E)-hexadecenoyl-CoA + AMP + diphosphate" ], [ "Q6P1M0-1", "protein_xref_rhea", "45256", "hexadecanoate(out) = hexadecanoate(in)" ], [ "Q6P1M0-1", "protein_xref_rhea", "33655", "(9Z)-octadecenoate(out) = (9Z)-octadecenoate(in)" ], [ "Q6P1M0-1", "protein_xref_rhea", "33639", "ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoA" ], [ "Q6P1M0-1", "protein_xref_rhea", "30751", "ATP + CoA + hexadecanoate = AMP + diphosphate + hexadecanoyl-CoA" ], [ "Q8TED1-1", "protein_xref_rhea", "16833", "2 glutathione + H2O2 = glutathione disulfide + 2 H2O" ], [ "O43598-1", "protein_xref_rhea", "57852", "a pyrimidine 2'-deoxyribonucleoside 5'-phosphate + H2O = 2-deoxy-D-ribose 5-phosphate + a pyrimidine nucleobase" ], [ "O43598-1", "protein_xref_rhea", "51132", "a purine 2'-deoxyribonucleoside 5'-phosphate + H2O = 2-deoxy-D-ribose 5-phosphate + a purine nucleobase" ], [ "P60891-1", "protein_xref_rhea", "15609", "ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)" ], [ "P21964-1", "protein_xref_rhea", "53096", "4-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 4-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine" ], [ "P21964-1", "protein_xref_rhea", "53104", "4-hydroxyestrone + S-adenosyl-L-methionine = 4-methoxyestrone + H(+) + S-adenosyl-L-homocysteine" ], [ "P21964-1", "protein_xref_rhea", "53092", "2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine" ], [ "P21964-1", "protein_xref_rhea", "53088", "2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 2-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine" ], [ "P21964-1", "protein_xref_rhea", "53100", "2-hydroxyestrone + S-adenosyl-L-methionine = 2-methoxyestrone + H(+) + S-adenosyl-L-homocysteine" ], [ "P21964-1", "protein_xref_rhea", "17877", "a catechol + S-adenosyl-L-methionine = a guaiacol + H(+) + S-adenosyl-L-homocysteine" ], [ "P21964-1", "protein_xref_rhea", "53108", "2-hydroxyestrone + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-estrone + H(+) + S-adenosyl-L-homocysteine" ], [ "Q6P988-1", "protein_xref_rhea", "45340", "[Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + H2O = (9Z)-hexadecenoate + [Wnt protein]-L-serine + H(+)" ], [ "Q99518-1", "protein_xref_rhea", "24468", "H(+) + N,N-dimethylaniline + NADPH + O2 = H2O + N,N-dimethylaniline N-oxide + NADP(+)" ], [ "P14618-1", "protein_xref_rhea", "18157", "ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate" ], [ "Q7L8W6-1", "protein_xref_rhea", "19753", "ATP + diphthine-[translation elongation factor 2] + NH4(+) = AMP + diphosphate + diphthamide-[translation elongation factor 2] + H(+)" ], [ "P30838-1", "protein_xref_rhea", "44100", "H2O + NAD(+) + octanal = 2 H(+) + NADH + octanoate" ], [ "Q9Y6V7-1", "protein_xref_rhea", "13065", "ATP + H2O = ADP + H(+) + phosphate" ], [ "O94953-1", "protein_xref_rhea", "60200", "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate" ], [ "P19404-1", "protein_xref_rhea", "29091", "a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) + NAD(+)" ], [ "Q6PHW0-1", "protein_xref_rhea", "32479", "2 iodide + L-tyrosine + 2 NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + 2 NADPH" ], [ "P33992-1", "protein_xref_rhea", "13065", "ATP + H2O = ADP + H(+) + phosphate" ], [ "P33992-1", "protein_xref_rhea", "13065", "ATP + H2O = ADP + H(+) + phosphate" ], [ "Q9Y315-1", "protein_xref_rhea", "12821", "2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate" ] ] }, "readme": "Name\n - Human UniProtKB Xref Rhea\n\nVersion\n - 1.11.2\n\nCreated on\n - 2021-10-15T06:33:28.159541\n\nModified on\n - 2022-01-18T12:49:15.225274\n\nCreated by\n - [jeetvora@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Amanda Bell [amandab2140@gwu.edu], Jonathon Keeney [keeneyjg@gwu.edu], Millicent Quartey [mquartey@email.gwu.edu]\n\nAuthors\n - Not Applicable []\n\nChecksum\n - \n\nUsability Domain\n - The Human UniProtKB Xref Rhea contains human [taxid:9606] UniProtKB canonical accessions cross-referenced to Rhea database accessions/identifiers. The dataset is derived from 2019-09 UniProtKB release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen. \n - Rhea\n\nDescription Domain\n Keywords\n - reactions\n - Rhea\n - cross-reference\n\n Pipeline Steps\n - Step-1: The script loads the UniProtKB canonical accessions that are cross-referenced to Rhea database accessions/identifiers from the triplestore containing triples from nt file and extracts the data as a csv dataset. \n\nExecution Domain\n Scripts - https://github.com/GW-HIVE/glygen-backend-integration/blob/master/pipeline/integrator/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: uniprot-proteome-homo-sapiens.nt\n URI: https:/data.glygen.org/ln2downloads/ebi/2021_04/uniprot-proteome-homo-sapiens.nt\n Output Subdomain\n Name: human_protein_xref_rhea.csv\n URI: https:/data.glygen.org/ln2releases/data/v-1.12.3/reviewed/human_protein_xref_rhea.csv\n Name: human_protein_xref_rhea.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-1.12.3/reviewed/human_protein_xref_rhea.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"3162\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"1\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"3935\"\n Name: \"xref_label\"\n Description: \"Label/Name associated with x-ref\"\n Unique Values: \"3935\"", "downloadurl": "/ln2data/releases/data/v-1.12.3/reviewed/human_protein_xref_rhea.csv" }