{ "bcoid": "GLY_000557", "title": "Glycan structure dictionary", "description": "Glycan dictionary is a list of terms which describe some structural aspect of the glycan composition ...", "filename": "glycan_dictionary.csv", "filetype": "csv", "categories": { "molecule": "glycan", "tags": "glycan dictionary", "file_type": "csv", "status": "Reviewed", "scope": "internal" }, "minitable": { "content": [ [ "G06953DR...", "2,6-Branched..." ], [ "G41145LF...", "2,6-sialyl-S..." ] ], "headers": [ "glytoucan_ac...", "term..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "glytoucan_ac" }, { "type": "string", "label": "term" }, { "type": "string", "label": "term_in_sentence" }, { "type": "string", "label": "publication" }, { "type": "string", "label": "definition" }, { "type": "string", "label": "term_xref" }, { "type": "string", "label": "best_match" }, { "type": "string", "label": "synonymns" }, { "type": "string", "label": "function" }, { "type": "string", "label": "disease_associations" }, { "type": "string", "label": "wikipedia" }, { "type": "string", "label": "essentials_of_glycobiology" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" } ], [ "G06953DR", "2,6-Branched O-mannose", "Collectively, these results strongly suggest that GnT-IX may be a novel beta1,6-N-acetylglucosaminyltransferase that is responsible for the formation of the 2,6-branched structure in the brain O-mannosyl glycan.[PMID:14617637]", "14617637|10469154", "(2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-[[(2R,3S,4S,5S,6S)-5-[(2S,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4S,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,6-trihydroxyoxan-2-yl]methoxy]-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:157265]", "CHEBI:157265|GlycoMotif:GGM.000056", "CHEBI:157265|GlycoMotif:GGM.000056|GTC:G06953DR", "5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2\u21923)-beta-D-galacto-hexopyranosyl-(1\u21924)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranosyl-(1\u21922)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2\u21923)-beta-D-galacto-hexopyranosyl-(1\u21924)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranosyl-(1\u21926)]-alpha-D-manno-hexopyranose|NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)]a-Man", "", "", "", "", "glycan_xref_dictionary", "GD000001" ], [ "G41145LF", "2,6-sialyl-Sulfo-LN", "The alpha2-6-sialylated 6-sulfo-LacNAc determinant defined by the antibody was significantly expressed on a majority of normal human peripheral B-lymphocytes as well as follicular B-lymphocytes in peripheral lymph nodes.[PMID:17728258]", "17728258", "", "GlycoMotif:GGM.000026", "GlycoMotif:GGM.000026|GTC:G41145LF", "6-sialyl-6-sulfo LN", "B-cell interaction with blood vessels and trafficking[PMID: 17728258]", "", "", "", "glycan_xref_dictionary", "GD000002" ], [ "G67383AR", "2-Fucosyl-GD1b", "They were fucosyl-Gv., fucoSyl-GDlb, and two uni que fucogangliosides having GMl or GOlb bas ic structure containing a substituent with the blood group B determinant. [PMID:3654655]", "3654655", "(2S,4S,5R,6R)-5-Acetamido-6-[(1S,2R)-2-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-1,3-dihydroxypropyl]-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxyoxane-2-carboxylic acid.[CHEBI:156680]", "CHEBI:156680|GlycoMotif:GGM.000103", "CHEBI:156680|GlycoMotif:GGM.000103|GTC:G67383AR", "6-deoxy-alpha-L-galacto-hexopyranosyl-(1\u21922)-beta-D-galacto-hexopyranosyl-(1\u21923)-2-acetamido-2-deoxy-beta-D-galacto-hexopyranosyl-(1\u21924)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2\u21928)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2\u21923)]-beta-D-galacto-hexopyranosyl-(1\u21924)-D-gluco-hexopyranose|Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc", "", "", "", "", "glycan_xref_dictionary", "GD000003" ], [ "G56526JU", "2-Fucosyl-GM1", "These glycolipid products were identified as asialo-Gs.., GM h and fucosyl-Gq, by comparison with authentic glycolipid samples.[PMID:3654655]", "3654655", "(2S,4S,5R,6R)-5-Acetamido-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:151476]", "KEGG:G12241|CHEBI:151476|CID:91849786|GlycoMotif:GGM.000101", "KEGG:G12241|CHEBI:151476|CID:91849786|GlycoMotif:GGM.000101|GTC:G56526JU", "Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc|6-deoxy-alpha-L-galacto-hexopyranosyl-(1\u21922)-beta-D-galacto-hexopyranosyl-(1\u21923)-2-acetamido-2-deoxy-beta-D-galacto-hexopyranosyl-(1\u21924)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2\u21923)]-beta-D-galacto-hexopyranosyl-(1\u21924)-D-gluco-hexopyranose", "", "", "", "", "glycan_xref_dictionary", "GD000004" ], [ "G10203DW", "3-Sialyl-LN (type 2)", "Using new crystal structures, we also provide the atomic resolution basis for the differential recognition of 3\u2032 and 6\u2032SiaLacNAc1\u20134 (with the Gal\u03b21\u20134 linkage known as Type 2 backbone16; Scheme 1) by TgMIC1-MARR, and make comparisons with the Type 1 chain isomer of 3\u2032SiaLacNAc1\u20134 (designated 3\u2032SiaLacNAc1\u20133).[PMID:19593815]", "19593815|15659615|2414279|8586620|2111348|23747419", "A linear amino trisaccharide consisting of \u03b1-neuraminyl, \u03b2-D-galactosyl and N-acetyl-D-glucosamine residues linked in a (2\u21923) and (1\u21924) sequence.[CHEBI:52472]", "KEGG:G00253|SugarBind_Ligand:109|GlycoEpitope:EP0314|CHEBI:52472|GlycoMotif:GGM.000034", "GTC:G10203DW|KEGG:G00253|SugarBind_Ligand:109|GlycoEpitope:EP0314|CHEBI:52472|GlycoMotif:GGM.000034", "A linear amino pentasaccharide consisting of a chain of three \u03b1-sialyl residues, a \u03b2-D-galactosyl residue and a \u03b2-D-glucose residue linked sequentially (2\u21928), (2\u21928), (2\u21923) and (1\u21924).[CHEBI:72444]", "", "Chronic gastritis[SugarBind_Ligand:109]|Toxoplasmosis[SugarBind_Ligand:109]|Peptic ulcers[SugarBind_Ligand:109]|Gastric cancer[SugarBind_Ligand:109]", "", "", "glycan_xref_dictionary", "GD000005" ], [ "G78706CK", "3'-Sulfo-Lewis a", "A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes.[PMID:11504739]", "11504739|17499486|17691854|12944557|19394320|7534477|11604107|28025252|9061363|9878545|11918697|24239607|28628803|25339106|21400496|17998215|12626387|11425799|12219077|10955596|9453593", "A branched amino trisaccharide consisting of N-acetylglucosamine having a fucosyl residue attached at the 4-position via an \u03b1-linkage and a 3-sulfated galactosyl residue attached at the 3-position via a \u03b2-linkage.[CHEBI:65149]", "GlycoEpitope:EP0009|CID:5289352|GlycoMotif:GGM.000030", "GTC:G78706CK|GlycoEpitope:EP0009|CID:5289352|GlycoMotif:GGM.000030", "3'-Sulfo-Lea|SuLe(a)|3'-sulpho-Le(a)|3-O-sulfo-Le(A)|3'-Sulfo Le^a|3'-Sulfo Lea|3'-Sulfo Lewis a", "SO3-3-Gal and the SO3-3-Lea blood group antigen bound to H.pylori.[GlycoEpitope:EP0009]", "", "", "", "glycan_xref_dictionary", "GD000006" ], [ "G12295TB", "3'-Sulfo-Lewis x", "A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes.[PMID:11504739]", "11504739|20695481|8688428|10536036|12770775|11352731|9784103|9022803", "A sulphated version of lewis X antigen which is a amino trisaccharide with structure \u03b2-D-Galp3S-(1\u21924)-[\u03b1-L-Fucp-(1\u21923)]-D-GlcpNAc that consists of N-acetyl-beta-D-glucosamine having an alpha-L-fucosyl residue attached at position 3 and a 3-sulfated beta-D-galactosyl residue attached at position 4; beta-D-Galp3S-(1\u21924)-[alpha-L-Fucp-(1\u21923)]-D-GlcpNAc in which the configuration at the anomeric centre of the reducing-end residue is beta. [CHEBI:65171]", "GlycoEpitope:EP0013|CID:5289353|CHEBI:65171|GlycoMotif:GGM.000029", "GTC:G12295TB|GlycoEpitope:EP0013|CID:5289353|CHEBI:65171|GlycoMotif:GGM.000029", "3'-sulfo-Le(x)|3'-Sulfo Lewis x|3'-sulfo Le^x|3'-sulfo Lex", "", "", "", "", "glycan_xref_dictionary", "GD000007" ], [ "G00659GQ", "6,6'-bisSulfo-Lewis x", "Comparison of the reactivity pattern of HEV with the reactivity of the pure 6-sulfo, 6'-sulfo, or 6,6'-bissulfo sialyl Lewis X determinant with hitherto known anti-sialyl Lewis X antibodies strongly suggested 6-sulfo sialyl Lewis X to be the best candidate for the major sulfated sialyl Lewis X determinant on HEV, followed by 6,6'-bissulfo sialyl Lewis X, whereas 6'-sulfo sialyl Lewis X was unlikely. [PMID:9556613]", "19756298|14593101|15175329|14568956|12163379|11919403|11520459|10728707|10200296|10528213|9712885|9556613|9456330|9556613|9257857|9164959|9015359|8958810|7560094|7485559|7538131|8161542|7684905", "(2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-hydroxy-2-(sulfooxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(sulfooxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:146095]", "GlycoEpitope:EP0016|CHEBI:146095|GlycoMotif:GGM.000028", "GlycoEpitope:EP0016|CHEBI:146095|GlycoMotif:GGM.000028|GTC:G00659GQ", "6,6'-DiSulfo Sialyl Lewis x|6,6-bisSulfo-Lewis x (6,60-bissulfo Lewis x )|6,6'- Disulfo Sialyl Lewis x|6,6'-bisSulfo-Lewis x|6,6'-bissulfo Lex|6,6'-Disulfo Sialyl Lewis x|6,6'-bissulfo Le^x", "lymphocyte homing[GlycoEpitope:EP0016]", "", "", "", "glycan_xref_dictionary", "GD000008" ], [ "G08371CD", "6-Sialyl-GalNAc", "mmunohistochemical distributions of carbohydrate antigens based on the type 2 chain in normal as well as fetal and neoplastic tissues of human gastrointestinal tract were investigated with a monoclonal antibody (MAb) H11 (specific for type 2 chain) alone and in combination with the two MAbs MSG15 (for alpha 2----6 sialylated type 2 chain) and IB9 (for the alpha 2----6 sialylated type 2 chain and glycoproteins having NeuAc alpha 2----6Gal-NAc), and 188C1 (for short- and long-chain Lex antigens) and FH2 (for the long-chain Lex antigen). [PMID: 1618643]", "1618643|6194157", "An amino disaccharide composed of N-acetylneuraminic acid and 2-(acetylamino)-2-deoxy-D-galactopyranose residues joined by an (\u03b1-2\u21926) glycosidic bond.[CHEBI:146820]", "GlycoEpitope:EP0352|KEGG:G00455|KEGG:G10625|CHEBI:146820|CID:11409652|GlycoMotif:GGM.000035", "GlycoEpitope:EP0352|KEGG:G00455|KEGG:G10625|CHEBI:146820|CID:11409652|GlycoMotif:GGM.000035|GTC:G08371CD", "Sialyl Tn antigen|6-Sialyl-GalNAc|6-Sialyl LN|6-Sialyl LN (type 1)|6-Sialyl LN (type 2)", "", "", "", "", "glycan_xref_dictionary", "GD000009" ], [ "G13157WZ", "6-Sulfo LacNac", "In the search for an additional marker to better dissect the two subsets we have explored the marker 6-sulfo LacNAc (slan).[PMID:31572354]", "31572354|31191513|29977237|29900053|30984181|28732748|26510404|28769928|31154896|27541644|25262889|26155414|28499587|27086951|27315572|26162403|26391152|31730025|12354382|27318477|23879812|25340085|24682513|21377044|21098395|18942710|23559493|23890755|22643330|23460612|23402811|22890025|19589615|32939325|20210806|17616642|22907335|16782032|22188261|21283706|29875315|32413173|19546436|19384158|1429720|30519676", "An oligosaccharide sulfate that is N-acetyllactosamine in which the hydroxy group at position 6 of the N-acetylglucosamine ring has been converted into its hydrogen sulfate derivative.[CHEBI:148005]", "GlycoEpitope:EP0141|CID:10322152|CHEBI:148005", "GlycoEpitope:EP0141|GTC:G13157WZ|CID:10322152|CHEBI:148005", "6-Sulfo LacNAc", "", "", "", "", "glycan_xref_dictionary", "GD000010" ], [ "G00672PE", "6'-Sulfo Sialyl Lewis x", "Studies using sulfotransferase-deficient mice showed that 6-sulfo sialyl Lewis X (6-sulfo sLe(x)), a major ligand for L-selectin that is expressed on the high endothelial venules (HEVs), plays critical roles in lymphocyte homing to the peripheral lymph nodes.[PMID:2288521]", "2288521|26137907|9400621|32744401|9556613|15972893|9015359|22691873|18652681|9722682|10435581|19458105|19359410|15228275|18250165|10536036|17944600|10460836|27993973|19149511|19150806|17172261|17142960|27956273|7578028|22260995|24519996|21596021|21982762|21775439|17334369|9710564|14593101|16227985|11895802|22750968|15157883|19067429", "A branched amino tetrasaccharide comprised of a trisaccharide chain of N-acetyl-\u03b1-neuraminic acid, 6-O-sulfo-\u03b2-D-glactose and N-acetyl-\u03b2-D-glucosamine residues linked sequentially (2\u21923) and (1\u21924), to the GlcNAC residue of which is also linked (1\u21923) an \u03b1-L-fucose residue.[CHEBI:71558]", "GlycoMotif:GGM.000025|CID:70698387|GlycoEpitope:EP0014|CHEBI:71558|SugarBind_Ligand:128", "GlycoMotif:GGM.000025|GTC:G00672PE|CID:70698387|GlycoEpitope:EP0014|CHEBI:71558|SugarBind_Ligand:128", "6'-sulfated sialyl Lewis x-|6'-sulfo-sLe(x)|Su-SaiLex|Su-Slex|6'-Sulfo-sialyl Lewis x", "lymphocyte homing[GlycoEpitope:EP0014]", "Influenza[SugarBind_Ligand:128]", "", "NBK453042", "glycan_xref_dictionary", "GD000011" ], [ "G74121RX", "9-O-Acetyl GD3", "To determine whether 9-O-acetyl GD3 (acGD3) has a general antiapoptotic potential, the apoptosis-sensitive Jurkat cell line and an apoptosis-sensitive variant of the cell line Molt-4 were preincubated with micromolar concentrations of acGD3 and then treated with inducers of apoptosis.[PMID:16432837]", "16432837|21507905|17512674|21930212|18194438|20739294|3216430|14724245|31373393|7558412|11273644|17385751|30694652|22894715|12973826|7859075|9749956|9874495|12486096|1989525|25330147|23478187|21807667|8486686|11465673|9511990|29270199|9268945|25045067|21618115|16434401|12493756|2302705|2198284|2685488|9328574|4055789|10096568|1644805|2582447", "", "GlycoEpitope:EP0064|CID:91852520|GlycoMotif:GGM.000093", "GTC:G74121RX|GlycoEpitope:EP0064|CID:91852520|GlycoMotif:GGM.000093", "acGD3|9-O-Acetylated GD3|9-O-Acetyl-GD3|9-O-Ac-GD3|CD60b", "", "pancreas cancer[GlycoEpitope:EP0064]", "", "", "glycan_xref_dictionary", "GD000012" ], [ "G47325QT", "9-O-Acetyl sialic acid", "Levels of 9-O-acetyl sialic acid provide a distinct way to define progenitors and thus facilitate the study of hematopoietic differentiation.[PMID:31411667]", "31411667|27936566|2509478|10049046|1826463", "N-acetyl-9-O-acetyl-alpha-neuraminic acid is a member of the class of N-acetylneuraminic acids that is alpha-neuraminic acid which has acetylated on N-5 and O-9. It has functional parent alpha-neuraminic acid.[CHEBI:84941]", "GlycoEpitope:EP0065|CID:13991612|CHEBI:84941", "GTC:G47325QT|GlycoEpitope:EP0065|CID:13991612|CHEBI:84941", "", "", "", "", "NBK453082-Chapter 77", "glycan_xref_dictionary", "GD000013" ], [ "G74353FF", "A Type 2", "Herein we report the synthesis of 3-aminopropyl glycosides of A (type 2) and B (type 2) tetrasaccharides via [3 + 1] block scheme.[PMID:27196314]", "27196314|6583282|8340255|18701592|21901093|2413709|8036794|1615929|3285099", "A branched amino tetrasaccharide comprising N-acetyl-\u03b2-D-glucosamine at the reducing end with a N-acetyl-\u03b1-D-galactosaminyl-(1\u21923)-[\u03b1-L-fucosyl-(1\u21922)]-\u03b2-D-galactosyl moiety attached at the 4-position.[CHEBI:62486]", "CID:53262376|GlycoEpitope:EP0257|CHEBI:62486|GlycoMotif:GGM.000038", "GTC:G74353FF|CID:53262376|GlycoEpitope:EP0257|CHEBI:62486|GlycoMotif:GGM.000038", "Blood group A (type 2)", "", "", "", "NBK453042", "glycan_xref_dictionary", "GD000014" ], [ "G62735WZ", "A2", "Landsteiner ABO system of blood groups is most important for transfusion medicine and has subtypes of A Antigen, A1 and A2, upon which further groups of A and AB have been classified.[PMID:28658771]", "29000000|28658771", "", "GlycoMotif:GGM.000041|CID:91852328", "GlycoMotif:GGM.000041|GTC:G62735WZ|CID:91852328", "", "", "", "", "", "glycan_xref_dictionary", "GD000015" ], [ "G24432YB", "Alpha-gal antigen", "Therefore, alpha-gal antigen might be eliminated after a prolonged culture, when using human cells.[PMID:31267683]", "31267683|29319188|29481481|26140655|30337555|29235434|22909134|28280265|7532618|23390540|22808845|29898796|22262104|31267683|25430953|22993330|23578170|21043478|28294277|27696820|15814276|17991149|25577211|30578545|19895316|28068870|18546155|32907757|26485996|9771839|12042247|27567275|12131678|23114154|19184002|29577591|29806570|15638815|21118731", "A glycosylgalactose that consists of \u03b2-D-galactose having an \u03b1-D-galactosyl residue at the 3-position.[CHEBI:62330]", "GlycoMotif:GGM.000015|CID:52939789|CHEBI:62330", "GTC:G24432YB|GlycoMotif:GGM.000015|CID:52939789|CHEBI:62330", "a-Gal antigen", "Has role as a carbohydrate allergen, epitope or an antigen.[CHEBI:62330]", "", "", "NBK453042", "glycan_xref_dictionary", "GD000016" ], [ "", "Alpha-galactosylceramide", "From 24 weeks of age, NZB/NZW F1 mice were injected with alpha-galactosylceramide (\u03b1-GalCer) or vehicle once a week for four weeks.[PMID:29844470]", "29844470|30421497|31575643|30745361|30953000|30556652|29617191|31689579|28872688|30195979|29940370|27004737|27198610|28743554|31649670|31484693|25752588|21383248|25527277|30821985|28947140|31244823|29311431|30803854|29576533|26101952|31213291|22412194|28067024|31199716|27354638|24465013|25445911|28120096|15630427|27803187|21392534|31075434|22683545|26191196|26811064|23935988|28623127|24913977|25434827|23420533|21839133|25314062|27325450|23874157", "", "", "", "alpha-GalCer|alpha-GalCers|\u03b1-GalCer", "", "", "", "", "glycan_xref_dictionary", "GD000017" ], [ "", "Asialo-biantennary", "Typical crystallizable fragment (Fc) glycans attached to the CH2 domain in therapeutic monoclonal antibodies (mAbs) are core-fucosylated and asialo-biantennary complex-type glycans, e.g., G2F (full galactosylation), G1aF (terminal galactosylation on the Man \u03b11-6 arm), G1bF (terminal galactosylation on the Man \u03b11-3 arm), and G0F (non-galactosylation).[PMID:30990348]", "30990348|17645671|20959391|18615430|16945378|2065054|3084472|2386787|22911097|24692304|17013932|7513972|6626573|10835250|9684342", "A binantennary glycan lacking sialic acid as non-reducing terminal residues on either antennae [https://en.wiktionary.org/wiki/asialobiantennary]", "", "", "asialo diantennary", "Used as an adjuvant for experimental vaccines [https://www.sciencedirect.com/topics/neuroscience/alpha-galactosylceramide]", "", "", "", "glycan_xref_dictionary", "GD000018" ], [ "G21856LC", "Asialo-GM1", "We compared the lateral structure of giant unilamellar vesicles (GUVs) composed of three pseudo binary mixtures of different glycosphingolipid (GSL), i.e. sulfatide, asialo-GM1 or GM1, with POPC.[PMID:29106974]", "29106974|3418980|26975993|8613364|9288228|26710925|24922516|6839313|1828259|2581667|8210226|25062498|9671150|10377092|6171919|3093429|6652964|3124753|8905612|18788941|1467432|8225593|2083955|6171918|7806377|1802483|7927723|9209156|21174147|2584393|12137200|6175621|2936802|8610366|21490162|1548508|3486908|26453755|7910939|3756909|1639356|3259967|2443562|3112077|2572647|25137483|2168971", "", "GlycoMotif:GGM.000099|CID:10169040|GlycoEpitope:EP0047|CHEBI:59216", "GlycoMotif:GGM.000099|GTC:G21856LC|CID:10169040|GlycoEpitope:EP0047|CHEBI:59216", "as-GM1|GA-1|Gangliotetraosylceramide|GgO4|Gg4|Asialo-GM1a", "", "Pleuropneumonia[SugarBind_Ligand:2]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:2]|Actinomycosis[SugarBind_Ligand:2]|Lazy leukocyte syndrome[SugarBind_Ligand:2]|Pertussis[SugarBind_Ligand:2]|Cutaneous lesions[SugarBind_Ligand:2]|Melioidosis[SugarBind_Ligand:2]|Candidiasis[SugarBind_Ligand:2]|Taiwan acute respiratory agent[SugarBind_Ligand:2]|Trachoma[SugarBind_Ligand:2]|Cystitis[SugarBind_Ligand:2]|Chronic gastritis[SugarBind_Ligand:2]|Peptic ulcers[SugarBind_Ligand:2]|Gastric cancer[SugarBind_Ligand:2]|Klebsiella pneumonia infection[SugarBind_Ligand:2]|Pneumonia[SugarBind_Ligand:2]|Legionnaires' disease[SugarBind_Ligand:2]|Gonorrhea[SugarBind_Ligand:2]|Gastroenteritis[SugarBind_Ligand:2]|Toxoplasmosis[SugarBind_Ligand:2]|Plague[SugarBind_Ligand:2]|Diarrhea[SugarBind_Ligand:2]", "", "", "glycan_xref_dictionary", "GD000019" ], [ "G72557NR", "B-GD1B", "The Molecular Modelling and 10 ns MD simulation of Botulinum Neuro Toxin/B-GD1A and BoNT/B-GD1B complex revealed that this toxin can interact with GD1A in the single binding mode and with GD1B in two binding modes.[PMID:22929125]", "27956354|22929125", "", "GlycoMotif:GGM.000104|CID:91847819|KEGG:G01803|CHEBI:153361", "GlycoMotif:GGM.000104|GTC:G72557NR|CID:91847819|KEGG:G01803|CHEBI:153361", "B-GD1b", "", "", "", "", "glycan_xref_dictionary", "GD000020" ], [ "G11485ID", "B-GM1", "The contribution of GM3 and GD3, which accounted for 95% of the ganglioside sialic acid at birth, decreased during the first 3 weeks of life. GM1, fucosyl-GM1, and B-GM1 were not detected at birth. [PMID: 3680254]", "3680254", "(2S,4S,5R,6R)-5-Acetamido-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-4-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CHEBI:147588]", "GlycoMotif:GGM.000102|CID:91853157|CHEBI:147588|SugarBind_Ligand:181", "GlycoMotif:GGM.000102|GTC:G11485ID|CID:91853157|CHEBI:147588|SugarBind_Ligand:181", "", "", "Cholera[SugarBind_Ligand:181]", "", "NBK453032", "glycan_xref_dictionary", "GD000021" ], [ "", "Biantennary", "We found an efficient isopropylidenation reaction that selectively protects the terminal Gal-3,4-OH of a biantennary complex-type nonasaccharide isolated from a natural source.[PMID:29249147]", "29249147|24991291|29409839|30325416|18083109|26926155|16715395|12634321|24211369|23115267|31907993|23360551|20861009|33142198|11442281|18687680|15680603|31888963|14686925|15819890|22530754|22098756|9346821|19341309|18529007|20580347|11784152|7773775|10913832|8547276|10463590|9404657|30525457|15316280|8068637|3881425|6425277|8576139|29956878|1576211|11129583|30421263|8069634|30973186|16704415|21612260|29806066|29443078", "Type of N-linked glycan in which two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [NBK453019-Glossary]", "", "", "diantennary", "", "", "", "NBK453020-Chapter 9", "glycan_xref_dictionary", "GD000022" ], [ "", "Biantennary complex", "The crystal structure of Pterocarpus angolensis lectin is determined in its ligand-free state, in complex with the fucosylated biantennary complex type decasaccharide NA2F, and in complex with a series of smaller oligosaccharide constituents of NA2F.[PMID:16704415]", "16704415|3731182|26747427|32597008|6626573|29249147|28597152|25045879|30325416|12634321|31888963|26926155|23360551|33142198|9404657|29956878|14686925|18687680|11784152|7773775|22530754|20580347|22098756|21612260|6425277|7691595|26780731|16285669|15819890|3924097|30448401|8547276|17049014|29408873", "A complex N-glycan that has two branches attached to the non-reducing terminal Man residues of the trimannosyl core. . Each branch is initiated with a GlcNAc and can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [CHEBI:156251]", "CHEBI:156251", "CHEBI:156251", "diantennary complex type", "", "", "", "", "glycan_xref_dictionary", "GD000023" ], [ "", "Bisecting GlcNac", "The presence of a bisecting GlcNAc and the occurrence of alpha 2-6-linked Neu5Ac in the most abundant N-glycans, are new features for hCG-beta.[PMID:1374031]", "1374031|29909448|29274553|32719771|22476631|31375533|26467158|27429195|20816221|26109616|30542567|30144245|25727145|29593568|32612952|9006930|19508951|16000695|32597008|19053837|22530754|30405631|19940114|32719549|9560299|29655002|10589784|29959030|20661133|9061364|31065629|20395209|29549127|30305426|29632412|24108122|24282611|27821068|14686925|10816579|25032906|30025558|9661906|8542600|31585439|29699572|27443163|30315103|23808883|18812317|19776078", "The bisecting GlcNAc is a modification of hybrid or complex N-linked glycans in which a single GlcNAc is added to the 3 position of the b-linked Man found in the trimannosyl core structure. The modification is catalyzed by beta 1,4-N-acetylglucosaminyltransferase III (GlcNAcT-III) or MGAT3 (E.C. 2.4.1.144). The addition of a bisecting GlcNAc on a hybrid or trimmed hybrid glycan prevents the subsequent action of N-glycan branching glycosyltransferases GlcNAcT-IV and GlcNAcT-V, but GlcNAcT3 can add a bisecting GlcNAc to the products of these enzymes. [PMID: 22476631]", "SID:163312364|KEGG:G13066", "SID:163312364|KEGG:G13066", "", "The bisecting GlcNAc of N-glycans regulates cellular signaling and tumor progression through modulating N-glycan/galectin interactions.[PMID: 22476631]Inhibits growth factor signaling and retards mammary tumor progression[PMID: 20395209]Integrin-mediated cell adhesion [PMID: 20816221]Important in fertilization and fetal development, neuritogenesis, immune tolerance, immunoglobulin G (IgG)[PMID: 32719771]", "mammary tumor.[PMID: 20395209]", "", "NBK453020", "glycan_xref_dictionary", "GD000024" ], [ "", "Bisialo-biantennary", "Using anion-exchange liquid chromatography mapping of the oligosaccharide units cleaved from the proteins by glycopeptidase F, compared with elution positions of standard oligosaccharide structures, coupled with monosaccharide compositional analysis, we find that the human plasma protein contained only bisialo-biantennary complex-type carbohydrate and asialo-biantennary complex carbohydrate, confirming earlier work published by this laboratory.", "2386787|2065054", "A binantennary glycan with sialic acid residues as non-reducing terminal residues on both antennae.", "", "", "disialo biantennary|disialo diantennary|disialylated biantennary|disialylated diantennary", "", "", "", "", "glycan_xref_dictionary", "GD000025" ], [ "", "Bisialo-biantennary complex-type", "Using anion-exchange liquid chromatography mapping of the oligosaccharide units cleaved from the proteins by glycopeptidase F , compared with elution positions of standard oligosaccharide structures , coupled with monosaccharide compositional analysis, we find that the human plasma protein contained only bisialo-biantennary complex-type carbohydrate and asialo-biantennary complex carbohydrate , confirming earlier work published by this laboratory.[PMID:2386787]", "2386787|26966183", "A binantennary glycan with sialic acid residues as non-reducing terminal residues on both antennae.", "", "", "Fully sialylated biantennary N-glycan", "", "", "", "NBK453089-Chapter 25", "glycan_xref_dictionary", "GD000026" ], [ "G54826OZ", "Blood group A (type 2) - Lewis y", "Monoclonal antibodies defining blood group A variants with difucosyl type 1 chain (ALeb) and difucosyl type 2 chain (ALey).[PMID:2417620]", "2417620", "A branched amino pentasaccharide consisting of the linear trisaccharide N-acetyl-\u03b1-D-galactosaminyl-(1\u21923)-\u03b2-D-galactosyl-(1\u21924)-N-acetyl-\u03b2-D-glucosamine having \u03b1-L-fucosyl residues attached at position 2 of the galactose and position 3 of the glucosamine. Corresponds to a partial structure of blood group A type 2 oligosaccharide.[CHEBI:62990]", "GlycoEpitope:EP0261|CHEBI:62990|CID:5289011|GlycoMotif:GGM.000039", "GlycoEpitope:EP0261|GTC:G54826OZ|CHEBI:62990|CID:5289011|GlycoMotif:GGM.000039", "Blood group A (type 2) (A-Ley)|Blood Group A Type 2 (difucosyl)|Blood group A (type 2) (A-Lewis Y)|A-Ley|A-Le^y", "", "", "", "", "glycan_xref_dictionary", "GD000027" ], [ "G37830TX", "Blood group A (Type 4)", "Moreover, we have found that \u03b1Gal, but not \u03b1GalNAc, is a weak binder itself for DC-SIGN, which could endow an additional binding mode for the blood group B antigen, but not for blood group A.[PMID:31283166]", "7800218|7521740|2458640|31283166", "", "GlycoMotif:GGM.000088|CID:91852258|KEGG:G00474|CHEBI:150159|SugarBind_Ligand:48", "GlycoMotif:GGM.000088|GTC:G37830TX|CID:91852258|KEGG:G00474|CHEBI:150159|SugarBind_Ligand:48", "", "", "Pyelonephritis[SugarBind_Ligand:48]|Acute cystitis[SugarBind_Ligand:48]", "", "", "glycan_xref_dictionary", "GD000028" ], [ "G00066MO", "Blood group A trisaccharide", "A readily detectable carbohydrate in the urine of two siblings with neuronal ceroid lipofuscinosis was found to be the blood group A trisaccharide.[PMID:7249368]", "19582848|7249368|8774717|2749874|28771597|30619340|2122121|11886841|2991755|12588002|3149698|7048329|7015594|10359132|8724140|1418679|1446307", "A branched amino trisaccharide consisting of \u03b2-D-galactose having an \u03b1-L-fucosyl residue at the 2-position and an N-acetyl-\u03b1-D-galactosaminyl residue at the 3-position.[CHEBI:61012]", "GlycoEpitope:EP0255|CID:49852448|KEGG:G10638|CHEBI:61012", "GlycoEpitope:EP0255|GTC:G00066MO|CID:49852448|KEGG:G10638|CHEBI:61012", "blood group A trisaccharide|blood group A type 1 trisaccharide", "", "", "", "", "glycan_xref_dictionary", "GD000029" ], [ "G66163TI", "Blood group A(1)", "he basis of blood group A(1) and A(2) phenotypes has been debated for many decades, and still the chemical basis is unresolved. [PMID:19121199]", "10942408|19121199", "An \u03b1-D-GalpNAc-(1\u21923)-[\u03b1-L-Fucp-(1\u21922)]-\u03b2-D-Galp-(1\u21923)-D-GlcpNAc having \u03b2-configuration at the reducing end anomeric centre.[CHEBI:62485]", "GlycoMotif:GGM.000044|GlycoEpitope:EP0256|CID:53262359|CHEBI:62485", "GlycoMotif:GGM.000044|GTC:G66163TI|GlycoEpitope:EP0256|CID:53262359|CHEBI:62485", "Blood group A (type 1)|blood group A antigen type 1", "", "", "", "", "glycan_xref_dictionary", "GD000030" ], [ "G44060QH", "Blood group A1 (type 3)", "The structure is essentially a repetitive A epitope attached to type 2 chain and is hereby called type 3 chain A. [PMID:2579390]", "2579390|19756298", "A branched amino heptasaccharide made up from two repeating (1\u21923)-linked N-acetyl-\u03b1-D-galactosaminyl-(1\u21923)-[\u03b1-L-fucosyl-(1\u21922)]-\u03b2-D-galactosyl units that are in turn joined to an N-acetyl-\u03b2-D-glucosamine residue via a (1\u21924)-linkage.[CHEBI:85665]", "CHEBI:85665|CID:91825676|GlycoMotif:GGM.000040", "GTC:G44060QH|CHEBI:85665|CID:91825676|GlycoMotif:GGM.000040", "Blood group A1 (type 3)|Blood Group A1", "", "", "", "", "glycan_xref_dictionary", "GD000031" ], [ "G62735WZ", "Blood group A2 (A-associated H type 3)", "The 'H NMR spectrum of the Aassociated H antigen (type 3 chain H) was characterized by\n the unusual presence of three n-anomeric resonances ('CJ'.~ =\n 3-4 Hz) in addition to five resonances from @-anomeric protons ('J1:2 = 7-9 Hz).[PMID: 3944091]", "3944091", "A branched amino hexasaccharide in which an \u03b1-L-fucosyl-(1\u21922)-\u03b2-D-galactosyl-(1\u21923)-N-acetyl-\u03b1-D-galactosaminyl-(1\u21923)-\u03b2-D-galactosyl-(1\u21924)-N-acetyl-\u03b2-D-glucosamine linear pentasaccharide carries at the galactose residue proximal to the reducing end a second \u03b1-L-fucosyl residue via a (1\u21922) linkage.[CHEBI:152543]", "CHEBI:152543|CID:91852328|GlycoMotif:GGM.000041", "CHEBI:152543|CID:91852328|GlycoMotif:GGM.000041|GTC:G62735WZ", "Blood Group A2|Fuca1-2Galb1-3GalNAca1-3(Fuca1-2)Galb1-4GlcNAcb|Fuc(a1-2)Gal(b1-3)GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)b-GlcNAc|Fucalpha1-2Galbeta1-3GalNAcalpha1-3(Fucalpha1-2)Galbeta1-4GlcNAcbeta|6-deoxy-alpha-L-galacto-hexopyranosyl-(1\u21922)-beta-D-galacto-hexopyranosyl-(1\u21923)-2-acetamido-2-deoxy-alpha-D-galacto-hexopyranosyl-(1\u21923)-[6-deoxy-alpha-L-galacto-hexopyranosyl-(1\u21922)]-beta-D-galacto-hexopyranosyl-(1\u21924)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranose|6-deoxy-alpha-L-galactopyranosyl-(1\u21922)-[6-deoxy-alpha-L-galactopyranosyl-(1\u21922)-beta-D-galactopyranosyl-(1\u21923)-2-acetamido-2-deoxy-alpha-D-galactopyranosyl-(1\u21923)]-beta-D-galactopyranosyl-(1\u21924)-2-acetamido-2-deoxy-beta-D-glucopyranose", "", "", "", "", "glycan_xref_dictionary", "GD000032" ], [ "G31734OS", "Blood group B (Type 1)", "It has been unknown whether NoV distinguishes between the type 1 and type 2 chains of A and B antigens. In this study, we synthesized A type 1, A type 2, B type 1, and B type 2 pentasaccharides in vitro and examined the function of the core structures in the binding between NoV virus-like particles (VLPs) and HBGAs. [PMID: 18701592]", "18701592|24749871|19387828|19208633|29562255", "\u03b1-D-Galp-(1\u21923)-[\u03b1-L-Fucp-(1\u21922)]-\u03b2-D-Galp-(1\u21923)-\u03b2-D-GlcpNAc with \u03b2 configuration at the anomeric carbon of the GlcNAc residue at the reducing end.[CHEBI:63242]", "GlycoMotif:GGM.000043|CID:56927779|CHEBI:63242", "GlycoMotif:GGM.000043|GTC:G31734OS|CID:56927779|CHEBI:63242", "blood group B type 1 tetrasaccharide", "", "", "", "", "glycan_xref_dictionary", "GD000033" ], [ "G34881WK", "Blood group B (Type 2)", "The detection of a B type 2 determinant is the first chemical evidence for the presence of an autologous difucosyl blood group B type 2 antigen in human adenocarcinoma cells.[PMID:2432062]", "2432062|27196314|18701592", "", "GlycoMotif:GGM.000037|GTC:G34881WK|GlycoEpitope:EP0262|GlycoMotif:GGM.000037", "GlycoMotif:GGM.000037|GTC:G34881WK|GlycoEpitope:EP0262", "blood group B type 2", "", "", "", "", "glycan_xref_dictionary", "GD000034" ], [ "G25216QA", "Blood group B (Type 4)", "The blood group B type-4 heptaglycosylceramide is a minor blood group B structure in human B kidneys in contrast to the corresponding A type-4 compound in A kidneys.[PMID:1390942]", "1390942|1841684", "", "GlycoMotif:GGM.000087", "GlycoMotif:GGM.000087|GTC:G25216QA", "", "", "", "", "", "glycan_xref_dictionary", "GD000035" ], [ "G00294TN", "Blood group H (Type 1)", "Blood group H type 1 [Fuc alpha (1,2)Gal beta (1,3)GlcNAc beta-->] is known as the precursor structure of the blood group determinant, Lewis b [Fuc alpha (1,2)Gal beta (1,3)(Fuc alpha (1,4))GlcNAc beta-->].[PMID:7718581]", "7718581|6309836|19208633|27431816|2432062|24219248|6352465|8499478|3348768|3718924", "", "GlycoMotif:GGM.000042|SugarBind_Ligand:153", "GTC:G00294TN|GlycoMotif:GGM.000042|SugarBind_Ligand:153", "H type 1", "", "Gastroenteritis[SugarBind_Ligand:153]", "", "", "glycan_xref_dictionary", "GD000036" ], [ "G00052MO", "Blood group H (type 2)", "We have examined the immunohistochemical distribution of H Type 1 and of H Type 2 substances of the ABO blood group system in human submandibular gland using either of the two anti-H monoclonal antibodies MAb 1E3 and MAb 3A5. MAb 3A5 was specific for H Type 2, and MAb 1E3 reacted with each of H Type 1-H Type 4 artificial antigens.[PMID:9405495]", "9405495|8082855|6177241|3944092|21406562|2410664|8731502|6203846|2238560|", "A branched amino tetrasaccharide consisting of N-acetyl-\u03b2-D-glucosamine at the reducing end having an \u03b1-L-fucosyl residue attached at the 3-position and an \u03b1-L-fucosyl-(1\u21922)-\u03b2-D-galactosyl moiety attached at the 4-position. A cancer-associated tetrasaccharide antigen which constitutes the core structure recognised by therapeutic antibody BR96. Conformational restriction around the GlcNAc residue is a key feature of its structure.[CHEBI:59045]", "GlycoEpitope:EP0018|CID:45266908|CHEBI:59045|GlycoMotif:GGM.000036", "GTC:G00052MO|GlycoEpitope:EP0018|CID:45266908|CHEBI:59045|GlycoMotif:GGM.000036", "Lewis y|Blood group H (type 2) (Ley)|Lewis b (Leb)|Lewis a|Blood group H (type 2) (Lewis Y)|Lewis b (Lewis b)|Blood group H (type 2) - Lewis y|H-Ley|H-Le^y|Lewis Y|6-deoxy-alpha-L-galactopyranosyl-(1\u21923)-[6-deoxy-alpha-L-galactopyranosyl-(1\u21922)-beta-D-galactopyranosyl-(1\u21924)]-2-acetamido-2-deoxy-beta-D-glucopyranose|alpha-L-Fuc-(1\u21922)-beta-D-Gal-(1\u21924)-[alpha-L-Fuc-(1\u21923)]-beta-D-GlcNAc|alpha-L-Fucp-(1\u21922)-beta-D-Galp-(1\u21924)-[alpha-L-Fucp-(1\u21923)]-beta-D-GlcpNAc|Fucalpha1-2Galbeta1-4(Fucalpha1-3)GlcNAcbeta|Fucalpha1-3(Fucalpha1-2Galbeta1-4)GclNAc|Lewis y Tetrasaccharide", "The expression of the fucosylated histo-blood group antigen CD174 in CD34+ hematopoietic progenitor cells and down-regulation of FUT1 in mature lymphocytes may be important factors influencing the homing process of hematopoietic stem cells to the bone marrow.[GlycoEpitope:EP0018]", "AIDS/acquired immune deficiency syndrome[GlycoEpitope:EP0018]|cholangiocarcinoma[GlycoEpitope:EP0018]|hepatocellular carcinoma[GlycoEpitope:EP0018]|Inappropriate tissue distribution of Ley blood-group antigens was observed in CCs(cholangiocarcinomas) and, much less frequently, in HCCs(hepatocellular carcinomas).[GlycoEpitope:EP0018]|Ley determinant is highly expressed in human immunodeficiency virus (HIV)-infected T cell lines and in CD3+ peripheral mature T cells of patients with acquired immune deficiency syndrome (AIDS) or with AIDS-related complex (ARC).[GlycoEpitope:EP0018]", "", "", "glycan_xref_dictionary", "GD000037" ], [ "G00052MO", "Blood group H (type 2) - Lewis y", "The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes.[PMID: 11479278]", "11479278", "A branched amino tetrasaccharide consisting of N-acetyl-\u03b2-D-glucosamine at the reducing end having an \u03b1-L-fucosyl residue attached at the 3-position and an \u03b1-L-fucosyl-(1\u21922)-\u03b2-D-galactosyl moiety attached at the 4-position. A cancer-associated tetrasaccharide antigen which constitutes the core structure recognised by therapeutic antibody BR96. Conformational restriction around the GlcNAc residue is a key feature of its structure.[CHEBI:59045]", "GlycoEpitope:EP0018|CID:45266908|CHEBI:59045|GlycoMotif:GGM.000045", "GTC:G00052MO|GlycoEpitope:EP0018|CID:45266908|CHEBI:59045|GlycoMotif:GGM.000045", "Lewis y|Blood group H (type 2) (Ley)|Lewis b (Leb)|Lewis a|Lewis b (Lewis b)|Blood group H (type 2) - Lewis y|H-Ley|H-Le^y|Lewis Y|H-Ley|H-Le^y|Lewis Y", "The expression of the fucosylated histo-blood group antigen CD174 in CD34+ hematopoietic progenitor cells and down-regulation of FUT1 in mature lymphocytes may be important factors influencing the homing process of hematopoietic stem cells to the bone marrow.[GlycoEpitope:EP0018]", "AIDS/acquired immune deficiency syndrome[GlycoEpitope:EP0018]|cholangiocarcinoma[GlycoEpitope:EP0018]|hepatocellular carcinoma[GlycoEpitope:EP0018]|Inappropriate tissue distribution of Ley blood-group antigens was observed in CCs(cholangiocarcinomas) and, much less frequently, in HCCs(hepatocellular carcinomas).[GlycoEpitope:EP0018]|Ley determinant is highly expressed in human immunodeficiency virus (HIV)-infected T cell lines and in CD3+ peripheral mature T cells of patients with acquired immune deficiency syndrome (AIDS) or with AIDS-related complex (ARC).[GlycoEpitope:EP0018]", "", "NBK453042", "glycan_xref_dictionary", "GD000038" ], [ "G98465JN", "Blood group H (Type 4)", "In addition, the blood group H type 4 chain structure was present together with Le(a) and Le(b) compounds.[PMID:1841684]", "11261842|1841684|11101633|9405495", "An amino hexasaccharide consisting of \u03b1-L-fucose, \u03b2-D-galactose, N-acetyl-\u03b1-D-galactosamine, \u03b1-D-galactose, \u03b2-D-galactose and \u03b2-D-glucose residues joined in sequence with (1\u21922)-, (1\u21923)-, (1\u21923)-, (1\u21924)- and (1\u21924)-linkages, respectively.[CHEBI:65245]", "GlycoMotif:GGM.000086|GTC:G98465JN|CID:10260428|SugarBind_Ligand:61|CHEBI:65245", "GlycoMotif:GGM.000086|GTC:G98465JN|CID:10260428|SugarBind_Ligand:61|CHEBI:65245", "", "", "Pyelonephritis[SugarBind_Ligand:61]", "", "", "glycan_xref_dictionary", "GD000039" ], [ "G97345NY", "C2-O-sLex", "PSGL-1 lacks 6-sulfo-sLex but contains sulfated tyrosine residues (Tyr-SO3)at positions 46, 48, and 51 and sLex in a core 2-based O-glycan (C2-O-sLex) on Thr at position 57.[PMID:12736247]", "12736247|19267921|21283832|15596301|17072011", "A seven-membered branched galactosamine oligosaccharide that consists of a branched tetrasaccharide unit \u03b1-Neu5Ac-(2\u21923)-\u03b2-D-Gal-(1\u21924)-[\u03b1-L-Fuc-(1\u21923)]-\u03b2-D-GlcNAc, attached by a glycosidic linkage to position 6 of the GalNAc residue of the trisaccharide \u03b1-Neu5Ac-(2\u21923)-\u03b2-D-Gal-(1\u21923)-D-GalNAc.[CHEBI:65192]", "GlycoMotif:GGM.000053|CID:91860725|KEGG:G10899|CHEBI:155160", "GlycoMotif:GGM.000053|GTC:G97345NY|CID:91860725|KEGG:G10899|CHEBI:155160", "", "", "", "", "", "glycan_xref_dictionary", "GD000040" ], [ "G04416BG", "Ceramide dihexosyl sulfate", "Although it has been reported that ceramide dihexosyl sulfate is present in human kidney, it is unlikely that it is present in equine kidney.[PMID:818074]", "818074", "A sulfatide with two hexose moieties (glucose and galactose) has been isolated from human kidney (Martensson E, Acta Chem Scand 1963, 17, 1174). Equimolar amounts of ceramide, glucose, galactose, and sulfate are found in the molecule. The sulfate group is esterified, as in sulfatides, with carbon 3 of the galactose moiety. The linkage between galactose and glucose is identical to lactose (b-1-4). Its fatty acid composition is similar to that of sulfatides.[http://cyberlipid.gerli.com/description/complex-lipids/glycolipids/glycosphingolipids/sulfosphingolipids/]", "GlycoMotif:GGM.000065", "GTC:G04416BG|GlycoMotif:GGM.000065", "", "", "", "", "", "glycan_xref_dictionary", "GD000041" ], [ "", "Chitin", "In this review, we will focus on the prevalence and structural function of chitin in bacteria, fungi, and protists, with a particular focus on the evolution of chitin synthases and the function of chitin oligosaccharides as a signaling molecule in symbiosis and immunity[PMID: 31102241]", "25738328|31102247|26982439|31685194|29197571|29182521|25725011|27787767|21736263|25300540|30840869|25081074|28250359|29763421|29910219|20161969|32019265|30879650|12587986|29773374|31376451|10906950|26096004|25595947|21673932|29452181|24083454|10856926|22732132|18657571|29175166|28842199|27592817|27302593|27339323|12705640|31635752|31063786|31151236|25940531|26093316|28962761|28093332|30875044|27723949|28119189|30600008|25081085|21673932", "An aminoglycan consisting of \u03b2-(1\u21924)-linked N-acetyl-D-glucosamine residues.[CHEBI:17029]", "CHEBI:17029", "CHEBI:17029", "", "", "", "", "", "glycan_xref_dictionary", "GD000042" ], [ "", "Chondroitin sulfate", "The industrial production of chondroitin sulfate (CS) uses animal tissue sources as raw material derived from different terrestrial or marine species of animals.[PMID: 31013685]", "31013685|27526113|27194526|26980567|28847361|24413804|29891297|29600622|25129732|31317901|29181550|31250530|22265655|25756648|29402610|17928217|20236040|28091940|30824935|26572336|31207331|21110089|30599999|20399897|27226567|19388612|23186102|31494830|28982096|30241863|30295666|25366475|20521042|29456007|31304829|18661362|28576008|29494632|30016441|26906924|24861964|23774590|31887904|31339761|12512856|26957048|29625000", "Any of a class of 10\u201a\u00c4\u00ee60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.[CHEBI:37397]", "CHEBI:37397|CID:24766", "CHEBI:37397| CID: 24766", "chondroitin polysulfate|chondroitin sulfate|chondroitin sulfates|chondroitin sulfuric acid|chondroitin sulphate|Chondroitinsulfate", "", "", "", "", "glycan_xref_dictionary", "GD000043" ], [ "G03277YI", "cisGM1", "Macrophage ganglioside patterns dramatically increase in complexity when murine peritoneal macrophages are stimulated in vivo with the appearance of the sialidase-sensitive monosialoganglioside GM1b (cisGM1) as a major component.[PMID: 9455923]", "9455923", "A member of the class of neuraminic acids that is neuraminic acid attached in sequence to \u03b2-D-galactopyranosyl, 2-acetamido-2-deoxy-\u03b2-D-galactopyranosyl, \u03b2-D-galactopyranosyl, and \u03b2-D-gucoopyranose units by (2\u21923), (1\u21923), (1\u21924), and (1\u21924) glycosidic linkages, respectively. It corresponds to the carbohydrate portion of ganglioside GM1b.[CHEBI:145580]", "GlycoMotif:GGM.000100|CID:91850212|CHEBI:145580|GlycoEpitope:EP0048|SugarBind_Ligand:92|KEGG:G00125", "GlycoMotif:GGM.000100|GTC:G03277YI|CID:91850212|CHEBI:145580|GlycoEpitope:EP0048|SugarBind_Ligand:92|KEGG:G00125", "GM1b", "", "Influenza[SugarBind_Ligand:92]", "", "NBK453054-Chapter 23", "glycan_xref_dictionary", "GD000044" ], [ "", "Complex-type N-glycans", "In this study, 32 new complex-type glycans are characterized containing the Le(x), Le(Y), and sialyl-Le(x) determinants, the bloodgroup A and H antigens, as well as the ALe(Y) determinant.[PMID:10988252]", "29902282|29212795|29343819|27705835|26745022|18399796|16825488|21964725|15864431|22890903|12417032|28039392|19426135|30253927|16794314|19806620|22975979|25931033|15201278|19129634|19129628|24032650|22530754|31021709|30973186|28091941|23115339|20829342|27304954|29090617|21802690|29725121|30471292|16581187|26098720|31080188|1930135|31888963|30844485|24014058|11129583", "Type of N-linked glycan in which at least two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.", "", "", "", "Involved in protein stability.[PMID:12417032]", "", "", "NBK453033-Chapter 17", "glycan_xref_dictionary", "GD000045" ], [ "G00033MO", "Core 2", "To investigate the biological roles of core 2 O-glycans, we produced and characterized mice deficient in one or more of the three known glycosyltransferases that generate core 2 O-glycans (C2GnT1, C2GnT2, and C2GnT3).[PMID: 19349303]", "19349303|30315106|23640779|26677400", "The trisaccharide \u03b2-D-Gal-(1\u21923)-[\u03b2-D-GlcNAc-(1\u21926)]-D-GalNAc with \u03b1 configuration at the anomeric centre of the N-acetylglucosamine residue at the reducing end.[CHEBI:62158]", "CID:52921656|CHEBI:62158", "GTC:G00033MO|CID:52921656|CHEBI:62158", "", "", "", "", "", "glycan_xref_dictionary", "GD000046" ], [ "G00035MO", "Core 3", "Mechanically, we revealed that mucin-type core 3 O-glycan was synthesized at the membrane-tethered MUC1 N terminus because of core 3 synthase expression in colon cancer cells.[PMID: 28745318]", "28745318|27259834|27143302|", "An amino disaccharide comprising an N-acetyl-\u03b2-D-glucosamine residue linked (1\u21923) to an N-acetyl-\u03b2-D-galactosamine residue at the reducing end.[CHEBI:71344]", "CID:25061208|CHEBI:71344", "GTC:G00035MO|CID:25061208|CHEBI:71344", "", "", "", "", "NBK453020-Chapter 9", "glycan_xref_dictionary", "GD000047" ], [ "G00037MO", "Core 4", "The results confirm the predicted existence of a beta1,6GlcNAc-transferase that functions in both core 2 and core 4 O-glycan branch formation.[PMID: 9988682]", "9988682|10747980|", "A branched amino trisaccharide comprising an N -acetyl-\u03b1-D-galactosamine residue at the reducing end, to which are (1\u21923)- and (1\u21926)-linked two N -acetyl-\u03b1-D-glucosamine residues.[CHEBI:71341]", "CID:25229562|CHEBI:71341", "GTC:G00037MO| CID:25229562|CHEBI:71341", "", "", "", "", "NBK20721-Chapter 8", "glycan_xref_dictionary", "GD000048" ], [ "G78059CC", "Core-fucosylated", "The approach was validated for selective capture and analysis of core fucosylated N-glycans present in complex glycan mixtures derived from mammalian serum IgG.[PMID:27678371]", "27678371|26514868|15538974|24914453|17049014|32078267|31268672|28674882|29956878|27798819|32044029|30962950|31548313|30907281|29090617|29571940|28800497|27629418|29733746|31623829|28768188|26897254|31451706|26514868|29427759|28982386|26587313|30940702|15538974|31249452|27282921|31229844|30445455|31325506|24732908|29209018|26965517|28609658|24914453|25573275|17049014|19218400|27012207|27139574|32078267|25861849|32561391|21374780|31669139|25732060|29408166|31268672|30472795|30614075|19003000|25664929", "Modification of the N-glycan core structure with fucose moiety attached at the innermost GlcNAc by FUT8 enzyme. Core Fuc is found on paucimannose, hybrid and complex type N-glycans. [https://doi.org/10.1016/bs.acr.2014.11.006].", "CID:70679232|CHEBI:70967|CHEBI:156499", "GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499", "Core Fuc|6-linked Fuc|Fuca6 to chitobiose core|a6-linked Fuc|a1-6 Fuc|Fuca6 to chitobiose core|Fuc a1-6 to chitobiose core|Fuca6 to internal GlcNAc|Fuc a1-6 to internal GlcNAc", "Required for signaling through TCR [PMID: 29434598]|VGF, PDGFr, and EGFr and TGFbeta receptor dysregulation in Fut8 KO mice [PMID:17132494]|IgG-Fcg receptor interactions destabilized by core Fuc [PMID:29062024]", "Emphysema|systemic lupus erythematosuslung cancer|autoimmunity|tumor metastasis", "", "NBK20721-Chapter 8", "glycan_xref_dictionary", "GD000049" ], [ "G78059CC", "Core-fucosylated biantennary", "The IFN-alpha14c N-glycans were shown to exhibit core-fucosylated biantennary glycans , with about 10% carrying an additional alpha1,3-linked fucose unit at the antennae.[PMID:9654101]", "9654101|15819890|28263871|26763099|22256781|23681398|25855029|10529240|26544759|8206921|33149259|8547276", "A biantennary glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc.", "CID:70679232|CHEBI:70967|CHEBI:156499", "GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499", "core-fucosylated diantennary", "", "", "", "NBK20721-Chapter 8", "glycan_xref_dictionary", "GD000050" ], [ "G78059CC", "Core-fucosylated biantennary complex-type", "The oligosaccharide structure at Asn(32 ) is a mixture of the monosialo and asialo forms of a core fucosylated biantennary complex-type oligosaccharide.[PMID:10731668]", "10731668", "A biantennary complex glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc.", "CID:70679232|CHEBI:70967|CHEBI:156499", "GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499", "core fucosylated diantennary complex-type", "", "", "", "", "glycan_xref_dictionary", "GD000051" ], [ "G80722US", "Cyclic sialyl 6-sulfo Lewis x", "Stimulation of the sialyl 6-sulfo Lewis X-positive colon cancer cell line with a calcium ionophore ionomycin markedly reduced sialyl 6-sulfo Lewis X and induced cyclic sialyl 6-sulfo Lewis X expression.[PMID:10728707]", "10728707|31222115|9990070|23088960", "", "GlycoMotif:GGM.000023|GlycoEpitope:EP0015|CID:70698321|CHEBI:71628", "GlycoMotif:GGM.000023|GTC:G80722US|GlycoEpitope:EP0015|CID:70698321|CHEBI:71628", "", "the accumulated intracellular cyclic sialyl 6-sulfo Lex determinant may function as a dormant pool of selectin ligands.[GlycoEpitope:EP0017]", "", "", "", "glycan_xref_dictionary", "GD000052" ], [ "G57710SU", "Cytolipin R", "The reaction can be inhibited completely by pure cytolipin R showing that (a) immune hemolysis can be mediated through lipid determinants in the membrane, and (b) that cytolipin R determinants are present in the intact erythrocyte membrane and exposed on the surface.[PMID:4110375]", "893368|4375678|51702|186204|4110375|5068000|24174198|6072378|389925|7054174", "A ceramide tetrahexoside isolated from rat lymphosarcoma. The structure of cytolipin R to be N-acetylgalactosaminyl(beta1-->3)galactosyl(alpha1-->3) galactosyl(beta1-->4)glucosyl ceramide.[PMID:5068000]", "GlycoMotif:GGM.000083|CID:91855936|KEGG:G00392|CHEBI:152175|SugarBind_Ligand:17", "GlycoMotif:GGM.000083|GTC:G57710SU|CID:91855936|KEGG:G00392|CHEBI:152175|SugarBind_Ligand:17", "", "", "Actinomycosis[SugarBind_Ligand:17]", "", "", "glycan_xref_dictionary", "GD000053" ], [ "", "Dermatan sulfate", "By utilizing sophisticated separation methods followed by compositional analysis, domain mapping, and tandem mass spectrometry coupled with analysis by a modified genetic algorithm approach, the structural motif for the decorin dermatan sulfate chain was determined.[PMID:29111696]", "27526113|29111696|29891297|26164146|30869126|7789716|8597249|12512856|31250530|17928217|12213784|27226567|31455633|28091940|19075609|31071403|15078125|18661328|20581662|17239765|15749837|2777747|20632047|8930750|7762784|31006321|26876822|1522290|131009|26986023|8161353|15315969|12543559|30637950|2525357|18156656|9692613|9200333|19661164|2299256|16075147|1126924|9774430|8537360|15563459|21077227|23275130|17137817|6447930|6209270", "Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated \u03b21\u21924-linked L-iduronyl-(\u03b11\u21923)-N-acetyl-D-galactosamine units.\n[CHEBI:18376]", "CHEBI:18376|CID:32756", "CHEBI:18376| CID: 32756", "beta-Heparin|Chondroitin sulfate B|Dermatan L-iduronate", "Wound healing[NBK453034-Chapter 7]|maintain the structure of the dermis.[NBK453056-Chapter 41]", "", "", "", "glycan_xref_dictionary", "GD000054" ], [ "", "Desialylated", "Furthermore, we found no evidence for 'desialylated' apoB100 glycans in any of the samples analyzed.[PMID:11588155]", "30015642|26168491|29492899|31774586|32321401|23780974|7600681|18045697|1450583|4137057|28911304|27562992|29950245|31978220|2408573|8612720|10910970|27195066|1434544|22175031|24517196|29794068|30101537|18972200|1478792|4440781|21229239|30844664|31351722|31330845|1872910", "A glycan from which sialyl groups have been removed. [https://en.wiktionary.org/wiki/desialylated]", "", "", "", "", "", "", "", "glycan_xref_dictionary", "GD000055" ], [ "", "Desialylated tetrasaccharide", "The structures of a desialylated tetrasaccharide , two monosialylated trisaccharides , and five other minor products were defined.[PMID:8384526]", "8384526", "A tetrasachharide (four branches) glycan from which sialyl groups have been removed.", "", "", "", "", "", "", "NBK453033-Chapter 17", "glycan_xref_dictionary", "GD000056" ], [ "", "Difucosylated tetra-antennary N-glycans", "While fucosylated N-glycans derived from serum haptoglobin of patients with CP slightly increased, di-fucosylated tetra-antennary N-glycans were observed only at this site in PC patients, and were absent in the haptoglobin of normal controls and individuals with CP.[PMID:18214858]", "18214858", "The tetra-antennary N-linked glycans that have four GlcNAc branches linked to the core and two fucose added.", "", "", "", "", "pancreatic cancer[PMID:18214858]", "", "", "glycan_xref_dictionary", "GD000057" ], [ "G79535HZ", "Dimeric Lewis x", "The carbohydrate antigen dimeric Lewis X (DimLex), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics.[PMID:32957489]", "32957489|31276881|12062524|15488731|1979361|8737237|17939723|7683631|11384108|11133015|17388629|15483381|12662048|3233598|18618154|21892456", "A six-membered glucosamine oligosaccharide consisting of two repeating units of \u03b2-D-Gal-(1\u21924)-[\u03b1-L-Fuc-(1\u21923)]-\u03b2-D-GlcNAc joined by a (1\u21923)-linkage.[CHEBI:61325]", "GlycoEpitope:EP0093|CID:50909845|CHEBI:61325|GlycoMotif:GGM.000031", "GTC:G79535HZ|GlycoEpitope:EP0093|CID:50909845|CHEBI:61325|GlycoMotif:GGM.000031", "DimLex^x|dimeric Le(x)|Lex-Lex|diLe(x)|Lewisx-Lewisx", "cancer-associated antigen[GlycoEpitope:EP0093]", "colonic cancer[GlycoEpitope:EP0093]|liver cancer[GlycoEpitope:EP0093]", "", "NBK453042-Chapter 14", "glycan_xref_dictionary", "GD000058" ], [ "G54792LL", "Diphosphorylated Man6", "Here we report that the single-chain variable domain (scFv) M6P-1 is a unique antibody fragment with specificity for Man6P monosaccharide that, through an array-screening approach against a number of phosphorylated N-glycans, is shown to bind mono- and diphosphorylated Man6 and Man7 glycans that contain terminal \u03b1Man6P(1 \u2192 2)\u03b1Man(1 \u2192 3)\u03b1Man.[PMID:26503547]", "26503547", "", "GlycoMotif:GGM.000054", "GTC:G54792LL|GlycoMotif:GGM.000054", "Diphosphorylated Man_6", "", "", "", "", "glycan_xref_dictionary", "GD000059" ], [ "G97932OH", "Disialosyl globopentaosylceramide", "Disialosyl globopentaosylceramide (DSGb5) is often expressed by renal cell carcinomas.[PMID:31339142]", "31339142|24637536|25864532|27344728|12084983|32567311|28205070|20663960|18214042", "Disialosyl globopentaosylceramide (DSGb5) is a ganglioside originally isolated from tissue extracts of renal cell carcinoma (RCC) with metastasis.[PMID:28205070]", "GlycoMotif:GGM.000082|GlycoEpitope:EP0098|CID:91860287|KEGG:G00181|SugarBind_Ligand:57", "GlycoMotif:GGM.000082|GTC:G97932OH|GlycoEpitope:EP0098|CID:91860287|KEGG:G00181|SugarBind_Ligand:57", "DSGb5|Disialosyl Gb5|V3NeuAcIV6NeuAc-Gb5Cer|Disialosylgalactosylgloboside", "promotes metastasis[PMID:28205070]", "prostate cancer[PMID:24637536]|renal cell carcinoma/RCC[GlycoEpitope:EP0098]|Pyelonephritis[SugarBind_Ligand:57]", "", "", "glycan_xref_dictionary", "GD000060" ], [ "G97932OH", "Disialyl Gb5", "The major disialoganglioside antigen isolated from ACHN cells, showing specific reactivity with 5F3, was characterized unequivocally as disialosyl Gb5 (V(3)NeuAcIV(6)NeuAcGb5) by identification of the core structure as globopentaosylceramide (Gb5) after enzymatic and acid hydrolysis, and by 2-dimensional (1)H-NMR spectroscopy.[PMID: 12084983]", "12084983", "", "GlycoEpitope:EP0098|CID:91860287|SugarBind_Ligand:57|KEGG:G00181", "GlycoEpitope:EP0098|GTC:G97932OH|CID:91860287|SugarBind_Ligand:57|KEGG:G00181", "", "", "renal cell carcinoma/RCC[GlycoEpitope:EP0098]|Pyelonephritis[SugarBind_Ligand:57]", "", "", "glycan_xref_dictionary", "GD000061" ], [ "G54937EM", "Disialyl I", "Here we present an example of promotion of binding of soluble-form FN from placenta or from hepatoma cells, having a specific carbohydrate epitope termed 'disialyl-I,' to K562 or VA13 cell surface in the presence of glycosphingolipid Gg3, which interacts specifically with disialyl-I[PMID:10640401]", "10640401", "", "GlycoEpitope:EP0095|CID:91849523", "GlycoEpitope:EP0095|GTC:G54937EM|CID:91849523", "disialyl-I", "", "", "", "", "glycan_xref_dictionary", "GD000062" ], [ "G93400AK", "Disialyl Lewis a", "Biosynthesis of disialyl Lewis a (Lea) was analyzed using previously cloned ST6GalNAc V and ST6GalNAc VI, which were responsible for the synthesis of alpha-series gangliosides.[PMID:12668675]", "12668675|17760270|15231659|12668106|30716533|32050430|22467657", "Disialyl Lewis is a sialyl Lewis a with an additional sialic acid attached at the C-6 position of penultimate GlcNAc. [PMID:15231659]", "GlycoEpitope:EP0040|CID:91854138|CHEBI:155549", "GTC:G93400AK |GlycoEpitope:EP0040|CID:91854138|CHEBI:155549", "disialyl Lea", "The 2-3,2-6 disialyl Lea determinant on epithelial cells may play a role in protecting normal epithelial cells.[GlycoEpitope:EP0040]", "Mucin antigen carrying 2-3 sialylated Le a antigen or 2-3, 2-6 disialylated Lc4 antigen in cancer patients had the lowest carbohydrate/protein ratio. Thus, the carbohydrate/protein ratio in the type 1 chain mucin antigens in sera of normal subjects is higher than that in sera of cancer patients.[GlycoEpitope:EP0040]", "", "", "glycan_xref_dictionary", "GD000063" ], [ "G01614ZM", "Disialyl T antigen", "The most potent glycoside was disialyl T antigen (NeuAcalpha2-3Galbeta1-3[NeuAcalpha2-6]GalNAc-R), followed by 3-sialyl T antigen (NeuAcalpha2-3Galbeta1-3GalNAc-R), structures expressed on O-linked glycoproteins as well as on gangliosides.[PMID: 15701648]", "29113555|17974963|33242079|12645620|15701648|26598643", "\u03b1-Neup5Ac-(2\u21926)-[\u03b1-Neup5Ac-(2\u21923)-\u03b2-D-Galp-(1\u21923)]-\u03b1-D-GalpNAc in which the anomeric configuration of the reducing-end N-acetyl-D-glucosamine residue is \u03b1.[CHEBI:71602]", "GlycoMotif:GGM.000014|CID:70698317|CHEBI:71602|GlycoEpitope:EP0023|KEGG:G00027", "GlycoMotif:GGM.000014|GTC:G01614ZM|CID:70698317|CHEBI:71602|GlycoEpitope:EP0023|KEGG:G00027", "di-sialyl T antigen|disialyl-T antigen|disialylated T-antigen", "associated with von Willebrand factor(VWF) plasma levels[GlycoEpitope:EP0023]", "", "", "", "glycan_xref_dictionary", "GD000064" ], [ "", "Disialylated biantennary", "FAB-MS, electrospray-mass spectrometry, and linkage analysis demonstrated that each monomer of rat CRP contained one oligosaccharide chain , predominantly a disialylated biantennary structure , attached to Asn-128.[PMID:8486673]", "22426998|17171781|25022802|24812685|24780636|26582205|9499382|22978794|22594947|8486673|20356825|1634621|9244386|12966096|1472054|24243045|19579232|27943633", "A biantennary glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues.", "", "", "disialylated diantennary", "appears in human transferrin[PMID: 24243045]|Appears in human apolipoprotein (apo) B-100.[PMID:2344297]", "galactosemia.[PMID:9499382]", "", "", "glycan_xref_dictionary", "GD000065" ], [ "", "Disialylated biantennary complex-type", "The glycan was shown to be a disialylated biantennary complex type oligosaccharide N-linked to 318 Asn.[PMID:11738084]", "11738084|9499382|9244386|24243045|12966096|25124522|19371135", "A biantennary complex glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues.", "", "", "", "appears in human transferrin[PMID:24243045]|Appears in human apolipoprotein (apo) B-100.[PMID:2344297]", "galactosemia.[PMID:9499382]", "", "", "glycan_xref_dictionary", "GD000066" ], [ "", "Disialylated fucosylated", "Disialylated fucosylated and monosialylated non-fucosylated oligosaccharides were also identified.[PMID:17591618]", "17591618", "A fucosylated glycan with two sialic acid components.", "", "", "", "", "", "", "NBK453041", "glycan_xref_dictionary", "GD000067" ], [ "G80062GG", "Forssman antigen", "Here we report the crystal structure of the complex between SLL-2 and Forssman antigen tetrasaccharide (GalNAc\u03b11-3GalNAc\u03b21-3 Gal\u03b11-4 Gal\u03b2 at 3.4 \u221a\u00d6 resolution.[PMID:28510705]", "28510705|31933576|28134301|7021748|1802714|7512587|7747818|23325748|268649|31816281|22015168|4147161|2857159|6267170|7293775|13367419|20636540|10460829|23255552|2675268|18955372|7020692|31784953|4114942|31273262|6257673|7696847|1916901|11169215|48262|26022515|6175621|31404475|6983878|8381954|10431785|3257757|6792413|25039359", "A linear amino pentasaccharide comprising N-acetyl-\u03b1-D-galactosamine, N-acetyl-\u03b2-D-galactosamine, \u03b1-D-galactose, \u03b2-D-galactose and \u03b2-D-glucose residues linked sequentially (1\u21923), (1\u21923), (1\u21924) and (1\u21924).CHEBI:85789]", "GlycoEpitope:EP0037|CID91825690|CHEBI:85789", "GTC:G80062GG |GlycoEpitope:EP0037|CID91825690|CHEBI:85789", "", "", "", "", "NBK453041", "glycan_xref_dictionary", "GD000068" ], [ "G80062GG", "Forssman glycolipid", "Analysis of metabolically labeled glycolipids released into the apical and basal culture medium, either as shed membrane vesicles or in budding viruses, also demonstrated the presence of the Forssman glycolipid on both apical and basolateral membranes of polarized cells.[PMID:3040119]", "3040119|268649|23240079|28134301|3495590|1138893|10460829|10506200|8855242|1955453|1933935|3355161|6773959|14573676|29898878|10431785|1747956|11214737|7423202|389939|3871816|6187373|16133832|469271|3753492|2695680|7037611|25703376|23798992|414913|1868069|7960243", "A linear amino pentasaccharide comprising N-acetyl-\u03b1-D-galactosamine, N-acetyl-\u03b2-D-galactosamine, \u03b1-D-galactose, \u03b2-D-galactose and \u03b2-D-glucose residues linked sequentially (1\u21923), (1\u21923), (1\u21924) and (1\u21924).[CHEBI:85789]", "GlycoMotif:GGM.000084|CID:91825690|KEGG:G00095|CHEBI:85789|GlycoEpitope:EP0037|SugarBind_Ligand:86", "GlycoMotif:GGM.000084|GTC:G80062GG|CID:91825690|KEGG:G00095|CHEBI:85789|GlycoEpitope:EP0037|SugarBind_Ligand:86", "Forssman antigen|Globopentosylceramide", "an antigenic marker for a major subpopulation of macrophages from murine spleen and peripheral lymph nodes[PMID:3495590]", "Pyelonephritis[SugarBind_Ligand:86]|Acute cystitis[SugarBind_Ligand:86]", "", "NBK453041", "glycan_xref_dictionary", "GD000069" ], [ "", "Fucose-containing tetraantennary", "The two major N-linked oligosaccharides of Namalwa EPO were fucose-containing tetraantennary and fucose-containing triantennary structures.[PMID:2550193]", "2550193", "A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of fucose.", "", "", "", "", "", "https://en.wikipedia.org/wiki/Forssman_antigen", "NBK453042", "glycan_xref_dictionary", "GD000070" ], [ "G91532KA", "Fucosyl GM1", "Unique localization of fucosyl GM1 implicates its possible role in cell adhesion and recognition in the nervous system.[PMID:8068725]", "6619101|16880505|9089399|29789847|8068725|19556222|1660040|2420639|9076515|15926079|19555091|2541996|16211870|1336587|21174147|14967068|18923900|30021910|16941490|27070150|8305235|10602885|2645049|7993838|10537341|3002616|8336147|15447995|8905401|11714535|9260862|32228455|3315641|8076384|2317201|3680254|6403518", "A branched amino hexasaccharide consisting of the linear sequence \u03b1-L-Fuc-(1\u21922)-\u03b2-D-Gal-(1\u21923)-\u03b2-D-GalNAc-(1\u21924)-\u03b2-D-Gal-(1\u21924)-D-Glc having a Neu5Ac residue attached to the inner galactose via an \u03b1-(2\u21923) linkage.[CHEBI:62686]", "GlycoEpitope:EP0049|CID:53356699|CHEBI:62686", "GTC:G91532KA |GlycoEpitope:EP0049|CID:53356699|CHEBI:62686", "", "", "small-cell lung cancer(SCLC)[GlycoEpitope:EP0049]|hepatoma[GlycoEpitope:EP0049]", "", "", "glycan_xref_dictionary", "GD000071" ], [ "", "Fucosylated asialo-biantennary", "We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054]", "2065054|17013932", "Describing a biantennary oligosaccharide that has no sialic acid component but has fucose.", "", "", "fucosylated asialo-diantennary", "", "", "", "", "glycan_xref_dictionary", "GD000072" ], [ "", "Fucosylated biantennary", "The profiles of the PSA N-glycans from the free and complexed molecules were quite similar to each other and consisted of fucosylated biantennary oligosaccharides as the major class.[PMID:17956937]", "17956937|30525457|1933856", "a biantennary glycan with two GlcNAc branches linked to the core and the addition of fucose.", "", "", "fucosylated bisialo-diantennary", "", "", "", "", "glycan_xref_dictionary", "GD000073" ], [ "", "Fucosylated bisialo-biantennary", "We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054]", "2065054", "Describing a biantennary oligosaccharide that has two sialic acid component and fucose added.", "", "", "Fucosylated biantennary", "", "", "", "", "glycan_xref_dictionary", "GD000074" ], [ "G02240AO", "Fucosylated LDN", "To date, oligomeric LDN and oligomeric fucosylated LDN (LDNF) have been found only on N-glycans from mammalian cells engineered to express Caenorhabditis elegansbeta4-GalNAc transferase and human alpha3-fucosyltransferase IX [Z. S. Kawar et al. (2005) J Biol Chem280, 12810-12819]. [PMID:16403022]", "16403022|28151933|19545571|22448293", "An amino trisaccharide comprising an acetamido-\u03b2-D-galactose and an \u03b1-L-fucose attached to an acetamidoglucose by 1\u21924 and 1\u21923 linkages, respectively.[CHEBI:61864]", "GlycoMotif:GGM.000017|GlycoEpitope:EP0151|CID:52921591|CHEBI:61864|MeSH:C488538|KEGG:G01594", "GlycoMotif:GGM.000017|GTC:G02240AO|GlycoEpitope:EP0151|CID:52921591|CHEBI:61864|MeSH:C488538|KEGG:G01594", "LDNF|Fucosylated lacdiNAc|LDN-F|(GalNAc)1 (GlcNAc)1 (LFuc)1", "", "", "", "", "glycan_xref_dictionary", "GD000075" ], [ "", "Fucosylated N-glycans", "Haptoglobin , an acute phase protein , has four potential N-glycosylation sites , although it remains unknown which site is responsible for the change in fucosylated N-glycans.[PMID:18214858]", "18214858|31141660|26869352|29790113|31931062", "The fucose from GDP-fucose is transferred to N-linked glycans.", "", "", "", "", "pancreatic cancer.[PMID: 26869352]", "", "", "glycan_xref_dictionary", "GD000076" ], [ "", "Fucosylated triantennary", "Asn184 is only partially glycosylated and substituted by fucosylated triantennary and small amounts of diantennary N-acetyllactosaminic glycans.[PMID:2513186]", "2513186|29642865|7679920|31110965|2551687|15051952|12943224", "A triantennary glycan with three GlcNAc branches linked to the core and the addition of fucose.", "", "", "", "appears in human alpha-fetoprotein (AFP).[PMID: 7679920]", "neoplastic diseases of the liver[PMID: 7679920 ]|hepatocellular carcinoma[PMID: 7679920].", "", "NBK453068", "glycan_xref_dictionary", "GD000077" ], [ "G67988RO", "Galabiosylceramide", "LacCer and its structural isomer, galabiosylceramide (Gb2, Gal\u03b2(1,4)Gal\u03b2-ceramide), are classified as ceramide dihexosides (CDH).[PMID:33360824]", "33360824|29099167|25582508|2824515|4027258|32854306|32868283|31319156|29530250|27367163|2564247|27727434|10216186|10460829|24992926|23590301|15702404|1854798|14761135|3600200|8603914|8601603|1965141|17400502|3840690|15959771|7930586|7721812|17095952|2500499|3815386|8842706|10746023|3928791|3782065|6440894", "A disaccharide consisting of \u03b2-D-galactopyranose having a D-galactopyranosyl residue attached at the 4-position via an \u03b1-linkage.[CHEBI:59314]", "GlycoEpitope:EP0113|CID:5288350|KEGG:G00497|KEGG:G10645|CHEBI:59314", "GlycoEpitope:EP0113|GTC:G67988RO|CID:5288350|KEGG:G00497|KEGG:G10645|CHEBI:59314", "", "", "tumor/lung[GlycoEpitope:EP0113]|tumor/gallbladder[GlycoEpitope:EP0113]|tumor/kidney[GlycoEpitope:EP0113]|tumor/pancreas[GlycoEpitope:EP0113]", "", "", "glycan_xref_dictionary", "GD000078" ], [ "G65889KE", "Galactosylceramide", "Galactosylceramide improved behavioral, neuropathological, and biochemical parameters in Cln3 Cln3 \u0394ex7/8 mice, paving the way for effective therapy for CLN3 disease and use of serum ceramide as a potential biomarker to track impact of therapies.[PMID:31393621]", "31393621|19941861|9883654|33006978|26735924|22032265|18035062|25129050|2802541|1761517|28660574|475780|2302222", "", "GlycoEpitope:EP0074|SugarBind_Ligand:1|GlycoMotif:GGM.000061", "GTC:G65889KE|GlycoEpitope:EP0074|SugarBind_Ligand:1|GlycoMotif:GGM.000061", "GalCer|Galactocerebroside|LC", "", "Pleuropneumonia[SugarBind_Ligand:1]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:1]|Lyme disease[SugarBind_Ligand:1]|Plague[SugarBind_Ligand:1]|Acquired immune deficiency syndrome[SugarBind_Ligand:1]", "", "", "glycan_xref_dictionary", "GD000079" ], [ "G33532XU", "Galnac disialyl Lc4 (Hexasaccharide)", "Therefore, a new marker for prostate cancer is urgently required. We examined expression of a novel carbohydrate antigen, beta1,4-GalNAc-disialyl-Lc(4), defined by the monoclonal antibody RM2, in prostate cancer using 75 cases of radical prostatectomy specimens.[PMID: 12084983]", "15704108|11278988|12084983|7509790", "(2R,4S,5R,6R)-5-Acetamido-2-[[(2R,3S,4R,5R,6S)-5-acetamido-4-[(2R,3R,4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-[(3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CID:91857945]", "GlycoEpitope:EP0097|CID:91857945|CHEBI:149360", "GlycoEpitope:EP0097|GTC:G33532XU|CID:91857945|CHEBI:149360", "", "", "prostate cancer[GlycoEpitope:EP0097]|renal cell carcinoma/RCC[GlycoEpitope:EP0097]", "", "", "glycan_xref_dictionary", "GD000080" ], [ "G99053DY", "Gb5", "LnbB, a member of the glycoside hydrolase family 20 isolated from Bifidobacterium bifidum, was shown to release GNB from Gb5 and GA1 oligosaccharides.[PMID:25839135]", "12401210|25839135|31540393|31140679|3028540|3674263|31339142|30026902|10721708|30671362|26176557|25039255|24044869|32567311|27857717|21491978|24910250|29077212|8014006|27107335|32679486|1747956|8679447|28352526|11341836|10837462|7960243|16158941|3297853|2431136|21734356|8625206|30732055|12716912|20128040|2582447|14659673", "A linear amino pentasaccharide comprising D-glucose at the reducing end with a \u03b2-D-galactosyl-(1\u21923)-N-acetyl-\u03b2-D-glucosaminyl-(1\u21923)-\u03b1-D-galactosyl-(1\u21924)-\u03b2-D-galactosyl moiety at the 4-position.[CHEBI:141842]", "GlycoMotif:GGM.000076|CID:53239691|KEGG:G00097|CHEBI:62311|SugarBind_Ligand:12", "GlycoMotif:GGM.000076|GTC:G99053DY|CID:53239691|KEGG:G00097|CHEBI:62311|SugarBind_Ligand:12", "Globopentaosylceramide", "", "Pyelonephritis[SugarBind_Ligand:12]|Actinomycosis[SugarBind_Ligand:12|Influenza[SugarBind_Ligand:12]", "", "NBK453016", "glycan_xref_dictionary", "GD000081" ], [ "G81983KG", "GD1", "Hormonal and metabolic disturbances observed in both adult and paediatric patients with Gaucher disease type 1 (GD1) are discussed in this review. The PubMed database was used to identify articles on endocrine and metabolic disorders in GD1.[PMID:31791361]", "5652802|25345088|31791361|29361370|31234327|30264864|25250137|7528216|31669751|20684311|16306603|10420586|7766692|31614613|26384672|31613991|19210136|8926633|29696051|32300455|7513313|26674302|20336376|24259734|31704237|21067946|30516933|27979707|26345314|30516941|31849452|27789132|30218706|29388611|20177787", "", "GlycoMotif:GGM.000105|CID:91859783|KEGG:G00126", "GlycoMotif:GGM.000105|GTC:G81983KG|CID:91859783|KEGG:G00126", "GD1c", "", "", "", "", "glycan_xref_dictionary", "GD000082" ], [ "G46677TE", "GD1a", "Exclusive exposure of rat oligodendrocytes to GD1a, but not other gangliosides, overcomes aggregated fibronectin-induced inhibition of myelin membrane formation, in vitro, and OPC differentiation in fibronectin aggregate containing cuprizone-induced demyelinated lesions in male mice. [PMID: 28899916]", "28899916|26860251|21930390|32906699|26054879|29951721|11745410|17653976|26119566|21554929|18435913|15342262|26865725|21151139|15716397|21492147|16942752|26973195|24449473|14999485|22735313|20589721|10521808|22929125|7827024|16897174|25062498|17227759", "A branched amino hexasaccharide consisting of the linear sequence \u03b1-Neu5Ac-(2\u21923)-\u03b2-D-Gal-(1\u21923)-\u03b2-D-GalNAc-(1\u21924)-\u03b2-D-Gal-(1\u21924)-\u03b2-D-Glc having a Neu5Ac residue attached to a galactose via an \u03b1-(2\u21923) linkage. The oligosaccharide of ganglioside GD1a.[CHEBI:59209]", "GlycoMotif:GGM.000107|CID:45266861|CHEBI:59209|GlycoEpitope:EP0056|SugarBind_Ligand:22|KEGG:G00111", "GlycoMotif:GGM.000107|GTC:G46677TE|CID:45266861|CHEBI:59209|GlycoEpitope:EP0056|SugarBind_Ligand:22|KEGG:G00111", "GD1alpha", "", "Gastroenteritis[SugarBind_Ligand:22]|Actinomycosis[SugarBind_Ligand:22]|Lazy leukocyte syndrome[SugarBind_Ligand:22]|Toxoplasmosis[SugarBind_Ligand:22]|Lyme disease[SugarBind_Ligand:22]|Botulism[SugarBind_Ligand:22]|Keratoconjunctivitis[SugarBind_Ligand:22]|Influenza[SugarBind_Ligand:22]", "", "", "glycan_xref_dictionary", "GD000083" ], [ "G37184KW", "GD1b", "Gangliosides have been known to play a role in the regulation of apoptosis in cancer cells. This study has employed disialyl-ganglioside GD1b to apoptosis in human breast cancer MCF-7 cells using exogenous treatment of the cells with GD1b and endogenous expression of GD1b in MCF-7 cells.[PMID: 27144558]", "27144558|24859332|18625966|7945223|32518172|26710925|31837178|20594196|30985655|11511306|1742806|11123278|7685064|2709011|33279873|22929125|9179156|17964572|8821498|32726962|26560950|2611779|10072058|20030259|16415013|10797556|11342695|8619520|21519903|16199892|23777091|30246056|10481046", "A branched amino hexasaccharide comprising a \u03b2-D-galactosyl-(1\u21924)-\u03b2-D-glucose disaccharide, the galactosyl residue of which carries \u03b2-D-galactosyl-(1\u21923)-N-acetyl-\u03b2-D-galactosaminyl and N-acetyl-\u03b1-neuraminyl-(2\u21928)-N-acetyl-\u03b1-neuraminyl disaccharide units through (2\u21924) and (2\u21923) linkages respectively. It is the carbohydrate portion of ganglioside GD1b.[CHEBI:59222]", "GlycoMotif:GGM.000108|CID:45266846|CHEBI:59222|GlycoEpitope:EP0059|SugarBind_Ligand:14", "GlycoMotif:0GGM.00108|GTC:G37184KW|CID:45266846|CHEBI:59222|GlycoEpitope:EP0059|SugarBind_Ligand:14", "", "", "", "", "NBK453023", "glycan_xref_dictionary", "GD000084" ] ] }, "readme": "Name\n - Glycan structure dictionary\n\nVersion\n - 1.11.2\n\nCreated on\n - 2021-03-31T13:03:41.839695\n\nModified on\n - 2022-01-26T10:19:07.488997\n\nCreated by\n - [rsn13@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Amanda Bell [amandab2140@gwu.edu], Jonathon Keeney [keeneyjg@gwu.edu], Millicent Quartey [mquartey@email.gwu.edu]\n\nAuthors\n - \n\nChecksum\n - \n\nUsability Domain\n - Glycan dictionary is a list of terms which describe some structural aspect of the glycan composition or structure. The terms are extracted with a combination of manual and automatic literature mining tools from various sources. It is an on-going process and the current list includes 180 terms..The terms can also be viewed on the GlyGen wikipedia:https://wiki.glygen.org/index.php/Glycan_structure_dictionary. To submit more terms please follow instructions provided on the GlyGen wikipedia page. \n\nDescription Domain\n Keywords\n - Glycan dictionary\n - structure\n - glycan\n\n Pipeline Steps\n - Step-0: The glycan dictionary was manually generated using multiple resources. \n\nExecution Domain\n Scripts\n\n Software Prerequisites\n\nI/O Domain\n Input Subdomain\n Name: glycan_dictionary.csv\n URI: https://data.glygen.org//ln2data/releases/data/v-1.11.2/reviewed/glycan_dictionary.csv\n Output Subdomain\n Name: glycan_dictionary.csv\n URI: http://data.glygen.org/ln2data/releases/data/v-1.12.1/reviewed/glycan_dictionary.csv\n Name: glycan_dictionary.stat.csv\n URI: http://data.glygen.org/ln2data/releases/data/v-1.12.1/reviewed/glycan_dictionary.stat.csv", "downloadurl": "/ln2data/releases/data/v-1.12.1/reviewed/glycan_dictionary.csv" }