{ "bcoid": "GLY_000607", "title": "Human Proteoform Phosphorylation Citations (UniProtKB)", "description": "", "filename": "human_proteoform_citations_phosphorylation_uniprotkb.csv", "filetype": "csv", "categories": { "species": "Homo sapiens", "molecule": "Protein", "tags": "Phosphorylation Citations UniProtKB", "file_type": "csv", "status": "Reviewed", "scope": "internal" }, "minitable": { "content": [ [ "P24928-1...", "Site-specifi..." ], [ "Q7Z698-1...", "Spred-2 stea..." ] ], "headers": [ "uniprotkb_ca...", "title..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "title" }, { "type": "string", "label": "journal_name" }, { "type": "string", "label": "publication_date" }, { "type": "string", "label": "authors" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "src_xref_key" }, { "type": "string", "label": "src_xref_id" } ], [ "P24928-1", "Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II.", "Transcription", "2015", "Voss K, Forne I, Descostes N, Hintermair C, Schuller R, Maqbool MA, Heidemann M, Flatley A, Imhof A, Gut M, Gut I, Kremmer E, Andrau JC, Eick D", "protein_xref_pubmed", "26566685", "protein_xref_uniprotkb", "P24928" ], [ "Q7Z698-1", "Spred-2 steady-state levels are regulated by phosphorylation and Cbl-mediated ubiquitination.", "Biochemical and biophysical research communications", "2006 Dec 29", "Lock P, I ST, Straffon AF, Schieb H, Hovens CM, Stylli SS", "protein_xref_pubmed", "17094949", "protein_xref_uniprotkb", "Q7Z698" ], [ "Q9P2Y5-1", "mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.", "Molecular cell", "2015 Jan 22", "Kim YM, Jung CH, Seo M, Kim EK, Park JM, Bae SS, Kim DH", "protein_xref_pubmed", "25533187", "protein_xref_uniprotkb", "Q9P2Y5" ], [ "Q9H8S9-1", "Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1.", "Oncogene", "2008 Jul 17", "Hirabayashi S, Nakagawa K, Sumita K, Hidaka S, Kawai T, Ikeda M, Kawata A, Ohno K, Hata Y", "protein_xref_pubmed", "18362890", "protein_xref_uniprotkb", "Q9H8S9" ], [ "P43405-1", "Complex phosphorylation dynamics control the composition of the Syk interactome in B cells.", "European journal of immunology", "2011 Jun", "Bohnenberger H, Oellerich T, Engelke M, Hsiao HH, Urlaub H, Wienands J", "protein_xref_pubmed", "21469132", "protein_xref_uniprotkb", "P43405" ], [ "Q9H8S9-1", "MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation.", "Current biology : CB", "2008 Mar 11", "Praskova M, Xia F, Avruch J", "protein_xref_pubmed", "18328708", "protein_xref_uniprotkb", "Q9H8S9" ], [ "Q5KSL6-1", "Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa.", "The Journal of biological chemistry", "2005 Dec 2", "Imai S, Kai M, Yasuda S, Kanoh H, Sakane F", "protein_xref_pubmed", "16210324", "protein_xref_uniprotkb", "Q5KSL6" ], [ "Q07666-1", "Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of Sam68.", "Structure (London, England : 1993)", "2011 Oct 12", "Morishita EC, Murayama K, Kato-Murayama M, Ishizuka-Katsura Y, Tomabechi Y, Hayashi T, Terada T, Handa N, Shirouzu M, Akiyama T, Yokoyama S", "protein_xref_pubmed", "22000517", "protein_xref_uniprotkb", "Q07666" ], [ "Q8WYL5-1", "A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia.", "The Journal of cell biology", "2004 May 24", "Nagata-Ohashi K, Ohta Y, Goto K, Chiba S, Mori R, Nishita M, Ohashi K, Kousaka K, Iwamatsu A, Niwa R, Uemura T, Mizuno K", "protein_xref_pubmed", "15159416", "protein_xref_uniprotkb", "Q8WYL5" ], [ "P04406-1", "Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase.", "Journal of proteome research", "2008 Feb", "Seo J, Jeong J, Kim YM, Hwang N, Paek E, Lee KJ", "protein_xref_pubmed", "18183946", "protein_xref_uniprotkb", "P04406" ], [ "P56945-1", "AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern.", "Cellular signalling", "2009 Sep", "Makkinje A, Near RI, Infusini G, Vanden Borre P, Bloom A, Cai D, Costello CE, Lerner A", "protein_xref_pubmed", "19454314", "protein_xref_uniprotkb", "P56945" ], [ "P02808-1", "Complete covalent structure of statherin, a tyrosine-rich acidic peptide which inhibits calcium phosphate precipitation from human parotid saliva.", "The Journal of biological chemistry", "1977 Mar 10", "Schlesinger DH, Hay DI", "protein_xref_pubmed", "838735", "protein_xref_uniprotkb", "P02808" ], [ "P43405-1", "The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.", "The EMBO journal", "2008 May 7", "Kulathu Y, Hobeika E, Turchinovich G, Reth M", "protein_xref_pubmed", "18369315", "protein_xref_uniprotkb", "P43405" ], [ "P23508-1", "The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells.", "Biochimica et biophysica acta", "2012 Jun", "Pangon L, Van Kralingen C, Abas M, Daly RJ, Musgrove EA, Kohonen-Corish MR", "protein_xref_pubmed", "22480440", "protein_xref_uniprotkb", "P23508" ], [ "O14796-1", "EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cgamma, Ca++, and Erk, leading to granule polarization.", "The Journal of experimental medicine", "2014 Apr 7", "Perez-Quintero LA, Roncagalli R, Guo H, Latour S, Davidson D, Veillette A", "protein_xref_pubmed", "24687958", "protein_xref_uniprotkb", "O14796" ], [ "Q05397-1", "Specific tyrosine phosphorylation of focal adhesion kinase mediated by Fer tyrosine kinase in suspended hepatocytes.", "Biochimica et biophysica acta", "2009 May", "Oh MA, Choi S, Lee MJ, Choi MC, Lee SA, Ko W, Cance WG, Oh ES, Buday L, Kim SH, Lee JW", "protein_xref_pubmed", "19339212", "protein_xref_uniprotkb", "Q05397" ], [ "P10451-1", "A Single Kinase Generates the Majority of the Secreted Phosphoproteome.", "Cell", "2015 Jun 18", "Tagliabracci VS, Wiley SE, Guo X, Kinch LN, Durrant E, Wen J, Xiao J, Cui J, Nguyen KB, Engel JL, Coon JJ, Grishin N, Pinna LA, Pagliarini DJ, Dixon JE", "protein_xref_pubmed", "26091039", "protein_xref_uniprotkb", "P10451" ], [ "P00519-1", "JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.", "Nature cell biology", "2005 Mar", "Yoshida K, Yamaguchi T, Natsume T, Kufe D, Miki Y", "protein_xref_pubmed", "15696159", "protein_xref_uniprotkb", "P00519" ], [ "P06401-1", "Stoichiometry and site-specific phosphorylation of human progesterone receptor in native target cells and in the baculovirus expression system.", "The Journal of biological chemistry", "1996 Aug 9", "Beck CA, Zhang Y, Altmann M, Weigel NL, Edwards DP", "protein_xref_pubmed", "8702648", "protein_xref_uniprotkb", "P06401" ], [ "P06401-1", "Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor.", "Molecular endocrinology (Baltimore, Md.)", "1995 Aug", "Zhang Y, Beck CA, Poletti A, Edwards DP, Weigel NL", "protein_xref_pubmed", "7476977", "protein_xref_uniprotkb", "P06401" ], [ "Q8NHL6-1", "Mutational analysis of immunoreceptor tyrosine-based inhibition motifs of the Ig-like transcript 2 (CD85j) leukocyte receptor.", "Journal of immunology (Baltimore, Md. : 1950)", "2002 Apr 1", "Bellon T, Kitzig F, Sayos J, Lopez-Botet M", "protein_xref_pubmed", "11907092", "protein_xref_uniprotkb", "Q8NHL6" ], [ "Q15170-1", "The Ser36-Ser37 pair in HeLa nuclear protein p21/SIIR mediates Ser/Thr phosphorylation and is essential for Rous sarcoma virus long terminal repeat repression.", "The Journal of biological chemistry", "1995 Oct 27", "Yeh CH, Zong WX, Shatkin AJ", "protein_xref_pubmed", "7592688", "protein_xref_uniprotkb", "Q15170" ], [ "P21730-1", "Identification of the major phosphorylation sites in human C5a anaphylatoxin receptor in vivo.", "The Journal of biological chemistry", "1995 Aug 11", "Giannini E, Brouchon L, Boulay F", "protein_xref_pubmed", "7642584", "protein_xref_uniprotkb", "P21730" ], [ "P08727-1", "Characterization of the major physiologic phosphorylation site of human keratin 19 and its role in filament organization.", "The Journal of biological chemistry", "1999 Apr 30", "Zhou X, Liao J, Hu L, Feng L, Omary MB", "protein_xref_pubmed", "10212274", "protein_xref_uniprotkb", "P08727" ], [ "P21730-1", "Human complement 5a (C5a) anaphylatoxin receptor (CD88) phosphorylation sites and their specific role in receptor phosphorylation and attenuation of G protein-mediated responses. Desensitization of C5a receptor controls superoxide production but not receptor sequestration in HL-60 cells.", "The Journal of biological chemistry", "2000 Jan 21", "Christophe T, Rabiet MJ, Tardif M, Milcent MD, Boulay F", "protein_xref_pubmed", "10636859", "protein_xref_uniprotkb", "P21730" ], [ "O00327-2", "Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.", "Cell research", "2013 Feb", "Wang Z, Wu Y, Li L, Su XD", "protein_xref_pubmed", "23229515", "protein_xref_uniprotkb", "O00327" ], [ "P15036-1", "CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.", "Proceedings of the National Academy of Sciences of the United States of America", "2013 Nov 26", "Guen VJ, Gamble C, Flajolet M, Unger S, Thollet A, Ferandin Y, Superti-Furga A, Cohen PA, Meijer L, Colas P", "protein_xref_pubmed", "24218572", "protein_xref_uniprotkb", "P15036" ], [ "Q8TC07-1", "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.", "Science signaling", "2011 Mar 15", "Rigbolt KT, Prokhorova TA, Akimov V, Henningsen J, Johansen PT, Kratchmarova I, Kassem M, Mann M, Olsen JV, Blagoev B", "protein_xref_pubmed", "21406692", "protein_xref_uniprotkb", "Q8TC07" ], [ "Q8TC07-1", "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.", "Science signaling", "2009 Aug 18", "Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK", "protein_xref_pubmed", "19690332", "protein_xref_uniprotkb", "Q8TC07" ], [ "O43526-1", "Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.", "Proceedings of the National Academy of Sciences of the United States of America", "2005 Dec 6", "Surti TS, Huang L, Jan YN, Jan LY, Cooper EC", "protein_xref_pubmed", "16319223", "protein_xref_uniprotkb", "O43526" ], [ "Q9BYG3-1", "Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.", "Nature structural & molecular biology", "2005 Nov", "Byeon IJ, Li H, Song H, Gronenborn AM, Tsai MD", "protein_xref_pubmed", "16244663", "protein_xref_uniprotkb", "Q9BYG3" ], [ "P08727-1", "Characterization of in vivo keratin 19 phosphorylation on tyrosine-391.", "PloS one", "2010 Oct 25", "Zhou Q, Snider NT, Liao J, Li DH, Hong A, Ku NO, Cartwright CA, Omary MB", "protein_xref_pubmed", "21049038", "protein_xref_uniprotkb", "P08727" ], [ "P10636-1", "Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262.", "The Journal of biological chemistry", "1995 Mar 31", "Drewes G, Trinczek B, Illenberger S, Biernat J, Schmitt-Ulms G, Meyer HE, Mandelkow EM, Mandelkow E", "protein_xref_pubmed", "7706316", "protein_xref_uniprotkb", "P10636" ], [ "O75952-1", "Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain.", "Biochemical and biophysical research communications", "2005 Apr 15", "Hsu HC, Lee YL, Cheng TS, Howng SL, Chang LK, Lu PJ, Hong YR", "protein_xref_pubmed", "15752768", "protein_xref_uniprotkb", "O75952" ], [ "Q9NRD5-1", "Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization.", "Neurochemistry international", "2010 Jul", "Shao X, Zhu L, Wang Y, Lu Y, Wang W, Zhu J, Shen Y, Xia J, Luo J", "protein_xref_pubmed", "20403402", "protein_xref_uniprotkb", "Q9NRD5" ], [ "P43403-1", "Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling.", "The Journal of biological chemistry", "1999 Mar 5", "Di Bartolo V, Mege D, Germain V, Pelosi M, Dufour E, Michel F, Magistrelli G, Isacchi A, Acuto O", "protein_xref_pubmed", "10037717", "protein_xref_uniprotkb", "P43403" ], [ "Q16790-1", "The role of carbonic anhydrase IX overexpression in kidney cancer.", "European journal of cancer (Oxford, England : 1990)", "2005 Dec", "Dorai T, Sawczuk IS, Pastorek J, Wiernik PH, Dutcher JP", "protein_xref_pubmed", "16310354", "protein_xref_uniprotkb", "Q16790" ], [ "Q6TGC4-1", "Identification and structural characterization of two 14-3-3 binding sites in the human peptidylarginine deiminase type VI.", "Journal of structural biology", "2012 Oct", "Rose R, Rose M, Ottmann C", "protein_xref_pubmed", "22634725", "protein_xref_uniprotkb", "Q6TGC4" ], [ "P05204-1", "Phosphorylation and subcellular redistribution of high mobility group proteins 14 and 17, analyzed by mass spectrometry.", "Protein science : a publication of the Protein Society", "2000 Jan", "Louie DF, Gloor KK, Galasinski SC, Resing KA, Ahn NG", "protein_xref_pubmed", "10739259", "protein_xref_uniprotkb", "P05204" ], [ "Q15046-1", "LysRS serves as a key signaling molecule in the immune response by regulating gene expression.", "Molecular cell", "2009 Jun 12", "Yannay-Cohen N, Carmi-Levy I, Kay G, Yang CM, Han JM, Kemeny DM, Kim S, Nechushtan H, Razin E", "protein_xref_pubmed", "19524539", "protein_xref_uniprotkb", "Q15046" ], [ "P48668-1", "Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.", "The Journal of biological chemistry", "1997 Mar 14", "Ku NO, Omary MB", "protein_xref_pubmed", "9054461", "protein_xref_uniprotkb", "P48668" ], [ "O95235-1", "Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis.", "The Journal of cell biology", "2003 Sep 1", "Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA", "protein_xref_pubmed", "12939256", "protein_xref_uniprotkb", "O95235" ], [ "P53999-1", "Gradual phosphorylation regulates PC4 coactivator function.", "The FEBS journal", "2006 Apr", "Jonker HR, Wechselberger RW, Pinkse M, Kaptein R, Folkers GE", "protein_xref_pubmed", "16689930", "protein_xref_uniprotkb", "P53999" ], [ "Q13542-1", "Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch.", "Nature", "2015 Mar 5", "Bah A, Vernon RM, Siddiqui Z, Krzeminski M, Muhandiram R, Zhao C, Sonenberg N, Kay LE, Forman-Kay JD", "protein_xref_pubmed", "25533957", "protein_xref_uniprotkb", "Q13542" ], [ "Q86YS7-1", "C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.", "Cell metabolism", "2011 Sep 7", "Xie X, Gong Z, Mansuy-Aubert V, Zhou QL, Tatulian SA, Sehrt D, Gnad F, Brill LM, Motamedchaboki K, Chen Y, Czech MP, Mann M, Kruger M, Jiang ZY", "protein_xref_pubmed", "21907143", "protein_xref_uniprotkb", "Q86YS7" ], [ "P08100-1", "Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.", "Cell", "2017 Jul 27", "Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE", "protein_xref_pubmed", "28753425", "protein_xref_uniprotkb", "P08100" ], [ "P07951-1", "Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies.", "Human mutation", "2014 Jul", "Marttila M, Lehtokari VL, Marston S, Nyman TA, Barnerias C, Beggs AH, Bertini E, Ceyhan-Birsoy O, Cintas P, Gerard M, Gilbert-Dussardier B, Hogue JS, Longman C, Eymard B, Frydman M, Kang PB, Klinge L, Kolski H, Lochmuller H, Magy L, Manel V, Mayer M, Mercuri E, North KN, Peudenier-Robert S, Pihko H, Probst FJ, Reisin R, Stewart W, Taratuto AL, de Visser M, Wilichowski E, Winer J, Nowak K, Laing NG, Winder TL, Monnier N, Clarke NF, Pelin K, Gronholm M, Wallgren-Pettersson C", "protein_xref_pubmed", "24692096", "protein_xref_uniprotkb", "P07951" ], [ "A6ND36-1", "Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling.", "Open biology", "2014 Feb 19", "Vogt J, Dingwell KS, Herhaus L, Gourlay R, Macartney T, Campbell D, Smith JC, Sapkota GP", "protein_xref_pubmed", "24554596", "protein_xref_uniprotkb", "A6ND36" ], [ "Q16612-1", "Regulation of glioma cell migration by serine-phosphorylated P311.", "Neoplasia (New York, N.Y.)", "2005 Sep", "McDonough WS, Tran NL, Berens ME", "protein_xref_pubmed", "16229809", "protein_xref_uniprotkb", "Q16612" ], [ "P18669-1", "Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.", "Nature communications", "2013", "Hitosugi T, Zhou L, Fan J, Elf S, Zhang L, Xie J, Wang Y, Gu TL, Aleckovic M, LeRoy G, Kang Y, Kang HB, Seo JH, Shan C, Jin P, Gong W, Lonial S, Arellano ML, Khoury HJ, Chen GZ, Shin DM, Khuri FR, Boggon TJ, Kang S, He C, Chen J", "protein_xref_pubmed", "23653202", "protein_xref_uniprotkb", "P18669" ], [ "Q9NVI1-3", "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.", "Cell", "2007 Apr 20", "Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ", "protein_xref_pubmed", "17412408", "protein_xref_uniprotkb", "Q9NVI1" ], [ "Q6PIZ9-1", "T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane.", "The Journal of experimental medicine", "1998 Aug 3", "Bruyns E, Marie-Cardine A, Kirchgessner H, Sagolla K, Shevchenko A, Mann M, Autschbach F, Bensussan A, Meuer S, Schraven B", "protein_xref_pubmed", "9687533", "protein_xref_uniprotkb", "Q6PIZ9" ], [ "Q99665-1", "Direct interaction of STAT4 with the IL-12 receptor.", "Archives of biochemistry and biophysics", "1999 Aug 1", "Yao BB, Niu P, Surowy CS, Faltynek CR", "protein_xref_pubmed", "10415122", "protein_xref_uniprotkb", "Q99665" ], [ "P00749-1", "Phosphorylation of human pro-urokinase on Ser138/303 impairs its receptor-dependent ability to promote myelomonocytic adherence and motility.", "The Journal of cell biology", "1997 May 5", "Franco P, Iaccarino C, Chiaradonna F, Brandazza A, Iavarone C, Mastronicola MR, Nolli ML, Stoppelli MP", "protein_xref_pubmed", "9151681", "protein_xref_uniprotkb", "P00749" ], [ "Q4G163-1", "A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs.", "Proceedings of the National Academy of Sciences of the United States of America", "2005 Mar 22", "Tung JJ, Hansen DV, Ban KH, Loktev AV, Summers MK, Adler JR 3rd, Jackson PK", "protein_xref_pubmed", "15753281", "protein_xref_uniprotkb", "Q4G163" ], [ "Q6NXT2-1", "Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.", "Cell", "2010 Sep 17", "Vermeulen M, Eberl HC, Matarese F, Marks H, Denissov S, Butter F, Lee KK, Olsen JV, Hyman AA, Stunnenberg HG, Mann M", "protein_xref_pubmed", "20850016", "protein_xref_uniprotkb", "Q6NXT2" ], [ "O43663-1", "Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1.", "Nature cell biology", "2007 Apr", "Neef R, Gruneberg U, Kopajtich R, Li X, Nigg EA, Sillje H, Barr FA", "protein_xref_pubmed", "17351640", "protein_xref_uniprotkb", "O43663" ], [ "P22314-1", "Identification of a region within the ubiquitin-activating enzyme required for nuclear targeting and phosphorylation.", "The Journal of biological chemistry", "1997 Apr 18", "Stephen AG, Trausch-Azar JS, Handley-Gearhart PM, Ciechanover A, Schwartz AL", "protein_xref_pubmed", "9099746", "protein_xref_uniprotkb", "P22314" ], [ "Q9Y4R8-1", "SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.", "Nature cell biology", "2013 Jan", "Fernandez-Saiz V, Targosz BS, Lemeer S, Eichner R, Langer C, Bullinger L, Reiter C, Slotta-Huspenina J, Schroeder S, Knorn AM, Kurutz J, Peschel C, Pagano M, Kuster B, Bassermann F", "protein_xref_pubmed", "23263282", "protein_xref_uniprotkb", "Q9Y4R8" ], [ "Q4G163-1", "CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit.", "Proceedings of the National Academy of Sciences of the United States of America", "2006 Jan 17", "Hansen DV, Tung JJ, Jackson PK", "protein_xref_pubmed", "16407128", "protein_xref_uniprotkb", "Q4G163" ], [ "Q494U1-1", "Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule.", "Biochimica et biophysica acta", "2008 Jun", "Sano E, Shono S, Tashiro K, Konishi H, Yamauchi E, Taniguchi H", "protein_xref_pubmed", "18191643", "protein_xref_uniprotkb", "Q494U1" ], [ "Q9H1A4-1", "Mitotic regulation of the human anaphase-promoting complex by phosphorylation.", "The EMBO journal", "2003 Dec 15", "Kraft C, Herzog F, Gieffers C, Mechtler K, Hagting A, Pines J, Peters JM", "protein_xref_pubmed", "14657031", "protein_xref_uniprotkb", "Q9H1A4" ], [ "P16066-1", "Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.", "Biochemistry", "2010 Nov 30", "Yoder AR, Stone MD, Griffin TJ, Potter LR", "protein_xref_pubmed", "20977274", "protein_xref_uniprotkb", "P16066" ], [ "P17544-6", "p38beta2-mediated phosphorylation and sumoylation of ATF7 are mutually exclusive.", "Journal of molecular biology", "2008 Dec 26", "Camuzeaux B, Diring J, Hamard PJ, Oulad-Abdelghani M, Donzeau M, Vigneron M, Kedinger C, Chatton B", "protein_xref_pubmed", "18950637", "protein_xref_uniprotkb", "P17544" ], [ "Q07912-1", "Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin.", "Molecular biology of the cell", "2011 Feb 15", "Shen H, Ferguson SM, Dephoure N, Park R, Yang Y, Volpicelli-Daley L, Gygi S, Schlessinger J, De Camilli P", "protein_xref_pubmed", "21169560", "protein_xref_uniprotkb", "Q07912" ], [ "P20594-1", "Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.", "Biochemistry", "2010 Nov 30", "Yoder AR, Stone MD, Griffin TJ, Potter LR", "protein_xref_pubmed", "20977274", "protein_xref_uniprotkb", "P20594" ], [ "P62805-1", "Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle.", "Molecular and cellular biology", "2008 Jan", "Pesavento JJ, Yang H, Kelleher NL, Mizzen CA", "protein_xref_pubmed", "17967882", "protein_xref_uniprotkb", "P62805" ], [ "P19484-1", "TFEB links autophagy to lysosomal biogenesis.", "Science (New York, N.Y.)", "2011 Jun 17", "Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A", "protein_xref_pubmed", "21617040", "protein_xref_uniprotkb", "P19484" ], [ "P08195-1", "Ecto-phosphorylation of CD98 regulates cell-cell interactions.", "PloS one", "2008", "Nguyen HT, Dalmasso G, Yan Y, Obertone TS, Sitaraman SV, Merlin D", "protein_xref_pubmed", "19065266", "protein_xref_uniprotkb", "P08195" ], [ "Q15648-1", "Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.", "Proceedings of the National Academy of Sciences of the United States of America", "2018 Jul 24", "Sharma S, Cermakova K, De Rijck J, Demeulemeester J, Fabry M, El Ashkar S, Van Belle S, Lepsik M, Tesina P, Duchoslav V, Novak P, Hubalek M, Srb P, Christ F, Rezacova P, Hodges HC, Debyser Z, Veverka V", "protein_xref_pubmed", "29997176", "protein_xref_uniprotkb", "Q15648" ], [ "Q6DKI7-1", "Identification of CD112R as a novel checkpoint for human T cells.", "The Journal of experimental medicine", "2016 Feb 8", "Zhu Y, Paniccia A, Schulick AC, Chen W, Koenig MR, Byers JT, Yao S, Bevers S, Edil BH", "protein_xref_pubmed", "26755705", "protein_xref_uniprotkb", "Q6DKI7" ], [ "P43268-1", "Extracellular signal-regulated kinase mitogen-activated protein kinase signaling initiates a dynamic interplay between sumoylation and ubiquitination to regulate the activity of the transcriptional activator PEA3.", "Molecular and cellular biology", "2009 Jun", "Guo B, Sharrocks AD", "protein_xref_pubmed", "19307308", "protein_xref_uniprotkb", "P43268" ], [ "P19021-1", "The novel kinase peptidylglycine alpha-amidating monooxygenase cytosolic interactor protein 2 interacts with the cytosolic routing determinants of the peptide processing enzyme peptidylglycine alpha-amidating monooxygenase.", "The Journal of biological chemistry", "1999 Dec 3", "Caldwell BD, Darlington DN, Penzes P, Johnson RC, Eipper BA, Mains RE", "protein_xref_pubmed", "10574929", "protein_xref_uniprotkb", "P19021" ], [ "Q9H0H5-1", "Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.", "PLoS biology", "2009 May 5", "Burkard ME, Maciejowski J, Rodriguez-Bravo V, Repka M, Lowery DM, Clauser KR, Zhang C, Shokat KM, Carr SA, Yaffe MB, Jallepalli PV", "protein_xref_pubmed", "19468302", "protein_xref_uniprotkb", "Q9H0H5" ], [ "Q14524-1", "Mass spectrometry-based identification of native cardiac Nav1.5 channel alpha subunit phosphorylation sites.", "Journal of proteome research", "2012 Dec 7", "Marionneau C, Lichti CF, Lindenbaum P, Charpentier F, Nerbonne JM, Townsend RR, Merot J", "protein_xref_pubmed", "23092124", "protein_xref_uniprotkb", "Q14524" ], [ "P13569-1", "Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications.", "Protein engineering, design & selection : PEDS", "2012 Jan", "McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, Wu X, Dai Q, Hong JS, Sorscher EJ, Kappes JC, Barnes S", "protein_xref_pubmed", "22119790", "protein_xref_uniprotkb", "P13569" ], [ "P46527-1", "Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27Kip1 in the acute promyelocytic leukemia cell line NB4.", "Blood", "2006 Feb 1", "Kardinal C, Dangers M, Kardinal A, Koch A, Brandt DT, Tamura T, Welte K", "protein_xref_pubmed", "16195327", "protein_xref_uniprotkb", "P46527" ], [ "P68431-1", "JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.", "Nature", "2009 Oct 8", "Dawson MA, Bannister AJ, Gottgens B, Foster SD, Bartke T, Green AR, Kouzarides T", "protein_xref_pubmed", "19783980", "protein_xref_uniprotkb", "P68431" ], [ "Q01804-1", "OTUD4 Is a Phospho-Activated K63 Deubiquitinase that Regulates MyD88-Dependent Signaling.", "Molecular cell", "2018 Feb 1", "Zhao Y, Mudge MC, Soll JM, Rodrigues RB, Byrum AK, Schwarzkopf EA, Bradstreet TR, Gygi SP, Edelson BT, Mosammaparast N", "protein_xref_pubmed", "29395066", "protein_xref_uniprotkb", "Q01804" ], [ "P29803-1", "Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.", "iScience", "2019 Sep 27", "Moutaoufik MT, Malty R, Amin S, Zhang Q, Phanse S, Gagarinova A, Zilocchi M, Hoell L, Minic Z, Gagarinova M, Aoki H, Stockwell J, Jessulat M, Goebels F, Broderick K, Scott NE, Vlasblom J, Musso G, Prasad B, Lamantea E, Garavaglia B, Rajput A, Murayama K, Okazaki Y, Foster LJ, Bader GD, Cayabyab FS, Babu M", "protein_xref_pubmed", "31536960", "protein_xref_uniprotkb", "P29803" ], [ "Q9NRM1-1", "A secretory kinase complex regulates extracellular protein phosphorylation.", "eLife", "2015 Mar 19", "Cui J, Xiao J, Tagliabracci VS, Wen J, Rahdar M, Dixon JE", "protein_xref_pubmed", "25789606", "protein_xref_uniprotkb", "Q9NRM1" ], [ "P04626-1", "Crystal Structure and Substrate Specificity of PTPN12.", "Cell reports", "2016 May 10", "Li H, Yang F, Liu C, Xiao P, Xu Y, Liang Z, Liu C, Wang H, Wang W, Zheng W, Zhang W, Ma X, He D, Song X, Cui F, Xu Z, Yi F, Sun JP, Yu X", "protein_xref_pubmed", "27134172", "protein_xref_uniprotkb", "P04626" ], [ "P08670-1", "Specific in vivo phosphorylation sites determine the assembly dynamics of vimentin intermediate filaments.", "Journal of cell science", "2004 Feb 29", "Eriksson JE, He T, Trejo-Skalli AV, Harmala-Brasken AS, Hellman J, Chou YH, Goldman RD", "protein_xref_pubmed", "14762106", "protein_xref_uniprotkb", "P08670" ], [ "Q14511-1", "Phosphorylation of human enhancer of filamentation (HEF1) on serine 369 induces its proteasomal degradation.", "Biochemical pharmacology", "2009 Oct 15", "Hivert V, Pierre J, Raingeaud J", "protein_xref_pubmed", "19539609", "protein_xref_uniprotkb", "Q14511" ] ] }, "readme": "Name\n - Human Proteoform Phosphorylation Citations (UniProtKB)\n\nVersion\n - 1.11.2\n\nCreated on\n - 2021-10-15T08:00:04.645468\n\nModified on\n - \n\nCreated by\n - [jeetvora@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Amanda Bell [amandab2140@gwu.edu], Jonathon Keeney [keeneyjg@gwu.edu], Millicent Quartey [mquartey@email.gwu.edu]\n\nAuthors\n - \n\nChecksum\n - \n\nDescription Domain\n Keywords\n - publications\n - PMID\n - journal\n - citations\n - authors\n - UniProtKB\n - PubMed\n - Phosphorylation\n\nExecution Domain\n Scripts\n\n Software Prerequisites\n\nI/O Domain\n Output Subdomain\n Name: human_proteoform_citations_phosphorylation_uniprotkb.csv\n URI: http://data.glygen.org/ln2data/releases/data/v-1.11.2/reviewed/human_proteoform_citations_phosphorylation_uniprotkb.csv\n Name: human_proteoform_citations_phosphorylation_uniprotkb.stat.csv\n URI: http://data.glygen.org/ln2data/releases/data/v-1.11.2/reviewed/human_proteoform_citations_phosphorylation_uniprotkb.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"16\"\n Name: \"motif_start\"\n Description: \"\"\n Unique Values: \"23\"\n Name: \"filter_flags\"\n Description: \"Filter tags/flags assigned to the mutation entries that have passed the mutation filter criteria\"\n Unique Values: \"19\"\n Name: \"sift_prediction\"\n Description: \"The SIFT qualitative prediction is derived from this score such that substitutions with a score < 0.05 are called 'deleterious' and all others are called 'tolerated\"\n Unique Values: \"3\"\n Name: \"somatic_status\"\n Description: \"The status of the variant whether it is germline (somatic status =0) or somatic (somatic status =1) variant\"\n Unique Values: \"1\"\n Name: \"chr_pos\"\n Description: \"Chromosome Position of a gene\"\n Unique Values: \"19\"\n Name: \"chr_id\"\n Description: \"\"\n Unique Values: \"10\"\n Name: \"dbsnp_id\"\n Description: \"\"A reference SNP ID number\"\n Unique Values: \"19\"\n Name: \"evidence_ECO:0000313\"\n Description: \"A type of evidence that is imported information used in an automatic assertion\"\n Unique Values: \"1\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"19\"\n Name: \"mim_id\"\n Description: \"Disease ID from the OMIM database\"\n Unique Values: \"1\"\n Name: \"description\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"begin_aa_pos\"\n Description: \"Start position of the amino acid in the sequence of a protein in UniProtKB\"\n Unique Values: \"18\"\n Name: \"cytogenic_band\"\n Description: \"One of the subregions of a chromosome visible microscopically after special staining\"\n Unique Values: \"14\"\n Name: \"aa_pos\"\n Description: \"Position of the amino acid in canonical sequence of protein in the UniProtKB database\"\n Unique Values: \"18\"\n Name: \"ref_aa\"\n Description: \"Reference amino acid residue\"\n Unique Values: \"9\"\n Name: \"sift_score\"\n Description: \"SIFT predicts whether an amino acid substitution is likely to affect protein function based on sequence homology and the physico-chemical similarity between the alternate amino acids. The data we provide for each amino acid substitution is a score and a qualitative prediction (either 'tolerated' or 'deleterious'). The score is the normalized probability that the amino acid change is tolerated so scores nearer zero are more likely to be deleterious. The qualitative prediction is derived from this score such that substitutions with a score < 0.05 are called 'deleterious' and all others are called 'tolerated\"\n Unique Values: \"10\"\n Name: \"alt_motif\"\n Description: \"Altered motif\"\n Unique Values: \"24\"\n Name: \"disease_xrefs\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"polyphen_score\"\n Description: \"The score assigned to a amino acid substitution by a tool called as PolyPhen (=Polymorphism Phenotyping) which predicts possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations. The PolyPhen score ranges from 0.0 (tolerated) to 1.0 (deleterious). Variants with scores of 0.0 are predicted to be benign. Values closer to 1.0 are more confidently predicted to be deleterious\"\n Unique Values: \"1\"\n Name: \"polyphen_prediction\"\n Description: \"\"The PolyPhen prediction values are - greater than 0.908 - \"\"Probably Damaging\"\"; greater than 0.446 and less than or equal to 0.908 - \"\"Possibly Damaging\"\"; less than or equal to 0.446 - \"\"Benign\"\"\"\n Unique Values: \"1\"\n Name: \"is_known_glycoprotein\"\n Description: \"Yes or no flag to denote if a protein is experimentally proven glycoprotein\"\n Unique Values: \"1\"\n Name: \"alt_nt\"\n Description: \"Alternative nucleotide\"\n Unique Values: \"1\"\n Name: \"protein_name\"\n Description: \"Protein name in the UniProtKB\"\n Unique Values: \"16\"\n Name: \"disease_evidence_ECO:0000313\"\n Description: \"The evidence that could be a PMID or a ClinVar ID that associates disease with the variant\"\n Unique Values: \"1\"\n Name: \"effect\"\n Description: \"The effect on glycosylation or N-sequon due to variation at site of glycosylated amino acid.\"\n Unique Values: \"3\"\n Name: \"end_aa_pos\"\n Description: \"End position of the amino acid in the sequence of a protein in UniProtKB\"\n Unique Values: \"18\"\n Name: \"mutation_type\"\n Description: \"Denotes whether mutation was reported with reference to amino acid or nucleotide\"\n Unique Values: \"1\"\n Name: \"disease_description\"\n Description: \"The disease description and/or definition \"\n Unique Values: \"1\"\n Name: \"do_id\"\n Description: \"Disease Ontology identifier\"\n Unique Values: \"1\"\n Name: \"evidence_ECO:0000269\"\n Description: \"A type of experimental evidence that is used in a manual assertion. Usually the values are PMIDs\"\n Unique Values: \"1\"\n Name: \"ref_nt\"\n Description: \"Reference nucleotide\"\n Unique Values: \"4\"\n Name: \"disease\"\n Description: \"The disease name for the cell line\"\n Unique Values: \"1\"\n Name: \"alt_aa\"\n Description: \"Altered amino acid residue\"\n Unique Values: \"10\"\n Name: \"cosmic_id\"\n Description: \"Legacy mutation identifier (COSM) in Catalogue of Somatic Mutations in Cancer (COSMIC) represents existing COSM mutation identifiers. This identifier remains the same between different assemblies (GRCh37 and GRCh38). All the COSM ids at the same genomic location have been collapsed into one representative COSM id. These ids are maintained to help track existing mutations\"\n Unique Values: \"1\"\n Name: \"ref_motif\"\n Description: \"Reference motif\"\n Unique Values: \"20\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"2\"\n Name: \"minor_allelic_frequency\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"gene_name\"\n Description: \"\"Official gene name/symbol assigned to the gene. Human gene name/symbol are approved by the HUGO Gene Nomenclature Committee (HGNC) and mouse gene name are approved by the Mouse Genome Informatics (MGI)\"\n Unique Values: \"17\"\n Name: \"disease_evidence_ECO:0000269\"\n Description: \"The PMID evidence for the association of the disease with the variant.\"\n Unique Values: \"1\"", "downloadurl": "/ln2data/releases/data/v-1.11.2/reviewed/human_proteoform_citations_phosphorylation_uniprotkb.csv" }