{
    "uniprot_canonical_ac": "A2AIR5-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2AIR5-1|NMD3A_MOUSE Isoform 1 of Glutamate receptor ionotropic, NMDA 3A  OS=Mus musculus OX=10090 GN=Grin3a PE=1 SV=1 CANONICAL=A2AIR5-1", 
        "length": 1135, 
        "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES"
    }, 
    "uniprot_id": "NMD3A_MOUSE", 
    "glycation": [], 
    "keywords": [
        "glycoprotein", 
        "predicted.uniprotkb_gly", 
        "reported.uniprotkb_gly", 
        "reported_with_glycan.glyconnect"
    ], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                    "id": "A2AIR5", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/11735224", 
                    "type": "PubMed", 
                    "id": "11735224"
                }
            ], 
            "title": "Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.", 
            "journal": "Genomics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Andersson O, Stenqvist A, Attersand A, von Euler G", 
            "date": "2001"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/14983056", 
                    "type": "PubMed", 
                    "id": "14983056"
                }
            ], 
            "title": "Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kattenstroth G, Tantalaki E, Sudhof TC, Gottmann K, Missler M", 
            "date": "2004"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/24297929", 
                    "type": "PubMed", 
                    "id": "24297929"
                }
            ], 
            "title": "GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.", 
            "journal": "Proc. Natl. Acad. Sci. U.S.A.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                    "id": "A2AIR5", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Perez-Otano I., Fiuza M., Gonzalez-Gonzalez I.", 
            "date": "2013"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/30635555", 
                    "type": "PubMed", 
                    "id": "30635555"
                }
            ], 
            "title": "Single-cell transcriptomic analysis of mouse neocortical development.", 
            "journal": "Nature communications", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ", 
            "date": "2019"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/30734226", 
                    "type": "PubMed", 
                    "id": "30734226"
                }
            ], 
            "title": "Immuno-Pharmacological Characterization of Presynaptic GluN3A-Containing NMDA Autoreceptors: Relevance to Anti-NMDA Receptor Autoimmune Diseases.", 
            "journal": "Molecular neurobiology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Olivero G, Vergassola M, Cisani F, Usai C, Pittaluga A", 
            "date": "2019"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/30899004", 
                    "type": "PubMed", 
                    "id": "30899004"
                }
            ], 
            "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", 
            "journal": "Nature communications", 
            "evidence": [
                {
                    "url": "https://glyconnect.expasy.org/browser/proteins/2354", 
                    "id": "2354", 
                    "database": "GlyConnect"
                }
            ], 
            "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", 
            "date": "2019"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/31601771", 
                    "type": "PubMed", 
                    "id": "31601771"
                }
            ], 
            "title": "Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula.", 
            "journal": "Science (New York, N.Y.)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Otsu Y, Darcq E, Pietrajtis K, Matyas F, Schwartz E, Bessaih T, Abi Gerges S, Rousseau CV, Grand T, Dieudonne S, Paoletti P, Acsady L, Agulhon C, Kieffer BL, Diana MA", 
            "date": "2019"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/31712124", 
                    "type": "PubMed", 
                    "id": "31712124"
                }
            ], 
            "title": "Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation.", 
            "journal": "Experimental neurology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martin-Ibanez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, Garcia-Torralba A, Pascual M, Pumarola M, Alberch J, Gines S, Martin ED, Segovia J, Soriano E, Canals JM", 
            "date": "2020"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/7306792", 
                    "type": "PubMed", 
                    "id": "7306792"
                }
            ], 
            "title": "Hypomyelinated mutant mice IV: peripheral myelin in jp msd.", 
            "journal": "Brain research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Billings-Gagliardi S, Adcock LH", 
            "date": "1981"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/9620802", 
                    "type": "PubMed", 
                    "id": "9620802"
                }
            ], 
            "title": "Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A.", 
            "journal": "Nature", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Das S, Sasaki YF, Rothe T, Premkumar LS, Takasu M, Crandall JE, Dikkes P, Conner DA, Rayudu PV, Cheung W, Chen HS, Lipton SA, Nakanishi N", 
            "date": "1998"
        }
    ], 
    "uniprot_ac": "A2AIR5", 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AIR5", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Grin3a"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AIR5", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "6430537F04; A830097C19Rik; mKIAA1973; N; NMD; NMDAR-L; NR3A"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AIR5", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Grin3a"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AIR5", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Kiaa1973"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AIR5#A2AIR5-1", 
            "isoform_ac": "A2AIR5-1", 
            "locus": {
                "end_pos": 49665229, 
                "strand": "+", 
                "start_pos": 49845081, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000093859", 
                        "id": "ENSMUST00000093859", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000091381", 
                        "id": "ENSMUSP00000091381", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AIR5-1|NMD3A_MOUSE Isoform 1 of Glutamate receptor ionotropic, NMDA 3A  OS=Mus musculus OX=10090 GN=Grin3a PE=1 SV=1 CANONICAL=A2AIR5-1", 
                "length": 1135, 
                "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AIR5#A2AIR5-2", 
            "isoform_ac": "A2AIR5-2", 
            "locus": {
                "end_pos": 49665229, 
                "strand": "+", 
                "start_pos": 49845081, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000093859", 
                        "id": "ENSMUST00000093859", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000091381", 
                        "id": "ENSMUSP00000091381", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AIR5-2|NMD3A_MOUSE Isoform 2 of Glutamate receptor ionotropic, NMDA 3A  OS=Mus musculus OX=10090 GN=Grin3a PE=1 SV=1 CANONICAL=A2AIR5-1", 
                "length": 1115, 
                "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:242443", 
            "resource": "KEGG Pathway", 
            "id": "mmu:242443", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9609736", 
            "description": "Assembly and cell surface presentation of NMDA receptors", 
            "resource": "Reactome", 
            "id": "R-MMU-9609736", 
            "name": "Assembly and cell surface presentation of NMDA receptors"
        }
    ], 
    "reaction_participants": [], 
    "function": [
        {
            "annotation": "Decrease in NMDA-receptor activity in alpha-neurexin-deficient synapses", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "annotation": "NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. During the development of neural circuits, plays a role in the synaptic refinement period, restricting spine maturation and growth (By similarity). By competing with GIT1 interaction with ARHGEF7/beta-PIX, may reduce GIT1/ARHGEF7-regulated local activation of RAC1, hence affecting signaling and limiting the maturation and growth of inactive synapses (PubMed:24297929). May also play a role in PPP2CB-NMDAR mediated signaling mechanism (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AIR5#function", 
                    "id": "A2AIR5", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "annotation": "Study found GluN1/GluN3A receptors are operational in neurons of the medial habenula (MHb), an epithalamic area controlling aversive physiological states; in the absence of glycinergic neuronal specializations in the MHb, glial cells tuned neuronal activity via GluN1/GluN3A receptors; reducing GluN1/GluN3A receptor levels in the MHb prevented place-aversion conditioning", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "annotation": "Thsese findings confirm the existence of presynaptic GluN3A-containing release-regulating NMDARs in mouse hippocampal glutamatergic nerve endings.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263284.1", 
                    "id": "NP_001263284.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8TCU5-1", 
            "protein_name": "Glutamate receptor ionotropic, NMDA 3A", 
            "sequence": {
                "length": 1115, 
                "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAPDDSRAGAQRDEPEPGTRRSPAPSPGARWLGSTLHGRGPPGSRKPGEGARAEALWPRDALLFAVDNLNRVEGLLPYNLSLEVVMAIEAGLGDLPLLPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSLVLHIPVISIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTQNNSKFHLGSIINITANLPSTQDLLSFLQIQLESIKNSTPTVVMFGCDMESIRRIFEITTQFGVMPPELRWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEHYVQDAMELVARAVATATMIQPELALIPSTMNCMEVETTNLTSGQYLSRFLANTTFRGLSGSIRVKGSTIVSSENNFFIWNLQHDPMGKPMWTRLGSWQGGKIVMDYGIWPEQAQRHKTHFQHPSKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEKIAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAVFLTLYEWKSPFGLTPKGRNRSKVFSFSSALNICYALLFGRTVAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRLHRAINTSFIEEKQQHFKTKRVEKRSNVGPRQLTVWNTSNLSHDNRRKYIFSDEEGQNQLGIRIHQDIPLPPRRRELPALRTTNGKADSLNVSRNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTSRTCES"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/128613", 
                    "id": "128613", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "GRIN3A", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q9R1M7-1", 
            "protein_name": "Glutamate receptor", 
            "sequence": {
                "length": 1135, 
                "sequence": "MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/128613", 
                    "id": "128613", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
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        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
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    ], 
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        "ac": "NP_001263284.1", 
        "name": "glutamate receptor ionotropic, NMDA 3A isoform 1 precursor", 
        "summary": ""
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                        "name": "calcium channel activity", 
                        "id": "GO:0005262"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", 
                        "pmid": "21873635", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
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                        "name": "signaling receptor activity", 
                        "id": "GO:0038023"
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
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                        "id": "GO:0042802"
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051721", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
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                        "id": "GO:0051721"
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                    {
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016594", 
                        "pmid": "", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                        "id": "GO:0016594"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042165", 
                        "pmid": "", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                        ], 
                        "name": "neurotransmitter binding", 
                        "id": "GO:0042165"
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                ], 
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                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", 
                        "pmid": "25144876", 
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                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutamatergic synapse", 
                        "id": "GO:0098978"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", 
                        "pmid": "24183704", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
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                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 
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                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
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                        "id": "GO:0005886"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", 
                        "pmid": "14507892", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
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                        "id": "GO:0043025"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", 
                        "pmid": "9620802", 
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                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
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                        "id": "GO:0045211"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017146", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", 
                        "pmid": "", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                        ], 
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", 
                        "pmid": "", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                        ], 
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                        "id": "GO:0045202"
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", 
                        "pmid": "", 
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                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "neuron projection", 
                        "id": "GO:0043005"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099061", 
                        "pmid": "", 
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                            {
                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
                            }
                        ], 
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            }, 
            {
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
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                            }
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                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060134", 
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                    {
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
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                                "id": "A2AIR5", 
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                    {
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
                                "id": "A2AIR5", 
                                "database": "UniProtKB"
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061000", 
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                                "url": "https://www.uniprot.org/uniprot/A2AIR5", 
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                                "database": "UniProtKB"
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            "resource": "RefSeq", 
            "name": "glutamate receptor ionotropic, NMDA 3A isoform 1 precursor"
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}