{
    "uniprot_canonical_ac": "A2RT18-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A2RT18-1|A2RT18_MOUSE Isoform 1 of Testis-expressed gene 16  OS=Mus musculus OX=10090 GN=Tex16 PE=1 SV=1 CANONICAL=A2RT18-1", 
        "length": 1139, 
        "sequence": "MESEKTKMESESLWMISDSESYSVDSHTEKGRASVSKINLIQIDETEKPRTKRYLMESDSEPSNTDSDSEGCELASAAVKYFIATKTFQQSSASSQFPKDSWSASRTINSDSESPVMSSDSMKYMKKAETCKSTCNLERLKAAHKSESLQDWLDAKRKQLDSDNAGYWDSSGKYQFSSIVPQESVGKRQGDLQTFQHSTEKKEVGSSSDKHQAQFGNERDQSDPKSKRYLIKTETGLDNEGFQMDEEREGCLVESDFRDSEREAHLLEAHRLGARKKENRPPGFWRPIILPPKLAQDKKTEEQKSVQQKDNRVSRIQLTRYKSEDKNVRFEEASSSLSDKPLSQEKLKKKHSYSFSPDSPTFTDEKHHRKASLKISGYKRQCKEYRYPHSCESLKYQISPIPLSSETCTSNVSSFVDSPTSKSPKSVTRKKSRRSITYSPEQGSQKCTRCFMEISNSSYHKCLINSDDSDSDSPLHGQISSHSKYSLRSKTIRHFKTSRNRPLSQSLDPQHSVVSRCSLHREDSKHSIDSTSYLHCESCASLQNLKGSSVTHTISKTTKKIMGQHSTHGHISGPVRLSQSESKFNLTAQPQNEDTPDVSDRNIKAEANVEDKLLYKDDTDHEDETNTEDETDGEDETDTEDEDEDDTKDKKDPKDKSDPDGSDPKDGNSENNTDSNNGSQPSGSSGPTGGPDSSNDGDSKNVTDHKSESDPTIDNATNSDVNLKYSTDETCTNNLDNASDLAEYFNHHNNADFKGRTNPASGNKTRTILDYISGSNNEDTGPRNTMIKEKIAYSENIRLLSNSYQNNVIKNGSEPSSNPSPQNSYGLPKDLDSNSNINPSNATNNTVNPNYGAKSTSTAIYKKTAALNYYSDINDVTGFTYEVRSSFVVNSNYFDRKKYAGRLSFALHTINAIDTNNVITCTSAVRSKFASEKTSVLDTKHSPRFSRFRSFNVIISPNYNTKNSQNANKSSISNIYNLPATELEINILSVLKIIYGNTPNFIAGTNYPDFLITSEFYEPLKLCRAYKIFDNQNIDAPFQDSAGYMDSHNSTYATGSMVALDAKESGFLKYFPRIQNTIGIKDPSCPFKVFSNQNILVPSFDVIVEAELPDIMKFTISSGAVNQLFQLRLQTGSRQNVDL"
    }, 
    "uniprot_id": "F6Z198_MOUSE", 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RT18", 
                    "id": "A2RT18", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "reaction_enzymes": [], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/11279525", 
                    "type": "PubMed", 
                    "id": "11279525"
                }
            ], 
            "title": "An abundance of X-linked genes expressed in spermatogonia.", 
            "journal": "Nature genetics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
                    "id": "NP_113559.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Wang PJ, McCarrey JR, Yang F, Page DC", 
            "date": "2001"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/16118233", 
                    "type": "PubMed", 
                    "id": "16118233"
                }
            ], 
            "title": "Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.", 
            "journal": "Human molecular genetics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
                    "id": "NP_113559.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Wang PJ, Page DC, McCarrey JR", 
            "date": "2005"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17660561", 
                    "type": "PubMed", 
                    "id": "17660561"
                }
            ], 
            "title": "Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.", 
            "journal": "Genetics", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
                    "id": "NP_113559.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Gallardo TD, John GB, Shirley L, Contreras CM, Akbay EA, Haynie JM, Ward SE, Shidler MJ, Castrillon DH", 
            "date": "2007"
        }
    ], 
    "uniprot_ac": "A2RT18", 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Tex16"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RT18", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Tex16"
        }
    ], 
    "reactions": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18#A2RT18-1", 
            "isoform_ac": "A2RT18-1", 
            "locus": {
                "end_pos": 112093529, 
                "strand": "-", 
                "start_pos": 112126780, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000038546", 
                        "id": "ENSMUST00000038546", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000048187", 
                        "id": "ENSMUSP00000048187", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2RT18-1|A2RT18_MOUSE Isoform 1 of Testis-expressed gene 16  OS=Mus musculus OX=10090 GN=Tex16 PE=1 SV=1 CANONICAL=A2RT18-1", 
                "length": 1139, 
                "sequence": "MESEKTKMESESLWMISDSESYSVDSHTEKGRASVSKINLIQIDETEKPRTKRYLMESDSEPSNTDSDSEGCELASAAVKYFIATKTFQQSSASSQFPKDSWSASRTINSDSESPVMSSDSMKYMKKAETCKSTCNLERLKAAHKSESLQDWLDAKRKQLDSDNAGYWDSSGKYQFSSIVPQESVGKRQGDLQTFQHSTEKKEVGSSSDKHQAQFGNERDQSDPKSKRYLIKTETGLDNEGFQMDEEREGCLVESDFRDSEREAHLLEAHRLGARKKENRPPGFWRPIILPPKLAQDKKTEEQKSVQQKDNRVSRIQLTRYKSEDKNVRFEEASSSLSDKPLSQEKLKKKHSYSFSPDSPTFTDEKHHRKASLKISGYKRQCKEYRYPHSCESLKYQISPIPLSSETCTSNVSSFVDSPTSKSPKSVTRKKSRRSITYSPEQGSQKCTRCFMEISNSSYHKCLINSDDSDSDSPLHGQISSHSKYSLRSKTIRHFKTSRNRPLSQSLDPQHSVVSRCSLHREDSKHSIDSTSYLHCESCASLQNLKGSSVTHTISKTTKKIMGQHSTHGHISGPVRLSQSESKFNLTAQPQNEDTPDVSDRNIKAEANVEDKLLYKDDTDHEDETNTEDETDGEDETDTEDEDEDDTKDKKDPKDKSDPDGSDPKDGNSENNTDSNNGSQPSGSSGPTGGPDSSNDGDSKNVTDHKSESDPTIDNATNSDVNLKYSTDETCTNNLDNASDLAEYFNHHNNADFKGRTNPASGNKTRTILDYISGSNNEDTGPRNTMIKEKIAYSENIRLLSNSYQNNVIKNGSEPSSNPSPQNSYGLPKDLDSNSNINPSNATNNTVNPNYGAKSTSTAIYKKTAALNYYSDINDVTGFTYEVRSSFVVNSNYFDRKKYAGRLSFALHTINAIDTNNVITCTSAVRSKFASEKTSVLDTKHSPRFSRFRSFNVIISPNYNTKNSQNANKSSISNIYNLPATELEINILSVLKIIYGNTPNFIAGTNYPDFLITSEFYEPLKLCRAYKIFDNQNIDAPFQDSAGYMDSHNSTYATGSMVALDAKESGFLKYFPRIQNTIGIKDPSCPFKVFSNQNILVPSFDVIVEAELPDIMKFTISSGAVNQLFQLRLQTGSRQNVDL"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18#F6WNY1-1", 
            "isoform_ac": "F6WNY1-1", 
            "locus": {
                "end_pos": 112093496, 
                "strand": "-", 
                "start_pos": 112126780, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000130247", 
                        "id": "ENSMUST00000130247", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000118847", 
                        "id": "ENSMUSP00000118847", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|F6WNY1-1|A2RT18_MOUSE Computationally mapped isoform of Testis-expressed gene 16  OS=Mus musculus OX=10090 GN=Tex16 PE=1 SV=1 CANONICAL=A2RT18-1", 
                "length": 1150, 
                "sequence": "FQMASASVQSLMESEKTKMESESLWMISDSESYSVDSHTEKGRASVSKINLIQIDETEKPRTKRYLMESDSEPSNTDSDSEGCELASAAVKYFIATKTFQQSSASSQFPKDSWSASRTINSDSESPVMSSDSMKYMKKAETCKSTCNLERLKAAHKSESLQDWLDAKRKQLDSDNAGYWDSSGKYQFSSIVPQESVGKRQGDLQTFQHSTEKKEVGSSSDKHQAQFGNERDQSDPKSKRYLIKTETGLDNEGFQMDEEREGCLVESDFRDSEREAHLLEAHRLGARKKENRPPGFWRPIILPPKLAQDKKTEEQKSVQQKDNRVSRIQLTRYKSEDKNVRFEEASSSLSDKPLSQEKLKKKHSYSFSPDSPTFTDEKHHRKASLKISGYKRQCKEYRYPHSCESLKYQISPIPLSSETCTSNVSSFVDSPTSKSPKSVTRKKSRRSITYSPEQGSQKCTRCFMEISNSSYHKCLINSDDSDSDSPLHGQISSHSKYSLRSKTIRHFKTSRNRPLSQSLDPQHSVVSRCSLHREDSKHSIDSTSYLHCESCASLQNLKGSSVTHTISKTTKKIMGQHSTHGHISGPVRLSQSESKFNLTAQPQNEDTPDVSDRNIKAEANVEDKLLYKDDTDHEDETNTEDETDGEDETDTEDEDEDDTKDKKDPKDKSDPDGSDPKDGNSENNTDSNNGSQPSGSSGPTGGPDSSNDGDSKNVTDHKSESDPTIDNATNSDVNLKYSTDETCTNNLDNASDLAEYFNHHNNADFKGRTNPASGNKTRTILDYISGSNNEDTGPRNTMIKEKIAYSENIRLLSNSYQNNVIKNGSEPSSNPSPQNSYGLPKDLDSNSNINPSNATNNTVNPNYGAKSTSTAIYKKTAALNYYSDINDVTGFTYEVRSSFVVNSNYFDRKKYAGRLSFALHTINAIDTNNVITCTSAVRSKFASEKTSVLDTKHSPRFSRFRSFNVIISPNYNTKNSQNANKSSISNIYNLPATELEINILSVLKIIYGNTPNFIAGTNYPDFLITSEFYEPLKLCRAYKIFDNQNIDAPFQDSAGYMDSHNSTYATGSMVALDAKESGFLKYFPRIQNTIGIKDPSCPFKVFSNQNILVPSFDVIVEAELPDIMKFTISSGAVNQLFQLRLQTGSRQNVDL"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18#F6Z198-1", 
            "isoform_ac": "F6Z198-1", 
            "locus": {
                "end_pos": 112011007, 
                "strand": "-", 
                "start_pos": 112093089, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000131304", 
                        "id": "ENSMUST00000131304", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000117689", 
                        "id": "ENSMUSP00000117689", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|F6Z198-1|F6Z198_MOUSE Computationally mapped isoform of Testis-expressed gene 16  OS=Mus musculus OX=10090 GN=Tex16 PE=4 SV=8 CANONICAL=A2RT18-1", 
                "length": 149, 
                "sequence": "XESDIIDMCKGVTKMCHYIISLPPDLPKPERQIPRPAHREDRSPRVQVPITTEPERVSSSVKRKADNTPSIQHLSMPMTTSALSYGPPVQYTSVQNQRLSESYSSSPRVEFPSDEGAFTLECDKGYKSETEIQYTDAFETLGGSFYYKT"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:83556", 
            "resource": "KEGG Pathway", 
            "id": "mmu:83556", 
            "name": ""
        }
    ], 
    "reaction_participants": [], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
            "annotation": "Germ-cell-specific sex-linked genes, like Tex16, are subject to meiotic sex-chromosome inactivation (MSCI) during spermatogenesis.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
                    "id": "NP_113559.2", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
            "annotation": "Tex16 is a gene that is expressed in testis that was identified in a genome-wide cDNA subtraction screen.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
                    "id": "NP_113559.2", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
            "annotation": "Transcripts highly enriched in ovary; gene identified as candidate female fertility factor.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
                    "id": "NP_113559.2", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
        "ac": "NP_113559.2", 
        "name": "testis expressed gene 16", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RT18", 
                                "id": "A2RT18", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "pre-mRNA binding", 
                        "id": "GO:0036002"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RT18", 
                                "id": "A2RT18", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "U6 snRNA binding", 
                        "id": "GO:0017070"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RT18", 
                                "id": "A2RT18", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "U2-type catalytic step 1 spliceosome", 
                        "id": "GO:0071006"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RT18", 
                                "id": "A2RT18", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "U2-type catalytic step 2 spliceosome", 
                        "id": "GO:0071007"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RT18", 
                                "id": "A2RT18", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Prp19 complex", 
                        "id": "GO:0000974"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 1051, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1049
        }, 
        {
            "end_pos": 413, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 411
        }, 
        {
            "end_pos": 458, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 456
        }, 
        {
            "end_pos": 587, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 585
        }, 
        {
            "end_pos": 673, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 671
        }, 
        {
            "end_pos": 679, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 677
        }, 
        {
            "end_pos": 703, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 701
        }, 
        {
            "end_pos": 717, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 715
        }, 
        {
            "end_pos": 739, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 737
        }, 
        {
            "end_pos": 765, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 763
        }, 
        {
            "end_pos": 813, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 811
        }, 
        {
            "end_pos": 843, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 841
        }, 
        {
            "end_pos": 846, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 844
        }, 
        {
            "end_pos": 970, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 968
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000034555", 
            "id": "ENSMUSG00000034555", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/83556", 
            "id": "83556", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039171", 
            "id": "IPR039171", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:83556", 
            "id": "mmu:83556", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1890545", 
            "id": "1890545", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/SGPNING/", 
            "id": "SGPNING", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=278055at2759", 
            "id": "278055at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14089", 
            "id": "PTHR14089", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559", 
            "id": "NP_113559", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113559.2", 
            "id": "NP_113559.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18", 
            "id": "A2RT18", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18-1", 
            "id": "A2RT18-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/F6WNY1", 
            "id": "F6WNY1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/F6WNY1-1", 
            "id": "F6WNY1-1", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/F6Z198", 
            "id": "F6Z198", 
            "database": "UniProtKB"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/F6Z198-1", 
            "id": "F6Z198-1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 127558.0, 
        "chemical_mass": 127558.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18", 
            "name": "Tex16", 
            "locus": {
                "end_pos": 112127326, 
                "strand": "+", 
                "start_pos": 112011007, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000034555", 
                        "id": "ENSMUSG00000034555", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RT18#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Testis-expressed gene 16"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RT18", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "testis expressed gene 16"
        }
    ]
}