{ "bcoid": "GLY_000064", "title": "Enzyme Mapping (Human Proteins)", "description": "List of Glycans identified by GlyTouCan Accessions with information on the human[taxid:9606] proteins ...", "filename": "human_glycan_enzyme.csv", "filetype": "csv", "categories": { "status": "Reviewed" }, "minitable": { "content": [ [ "G00221CZ...", "P26572-1..." ], [ "G00221CZ...", "Q3V5L5-1..." ] ], "headers": [ "glytoucan_ac...", "uniprotkb_ca..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "glytoucan_ac" }, { "type": "string", "label": "uniprotkb_canonical_ac_enzyme" }, { "type": "string", "label": "gene_name_enzyme" }, { "type": "string", "label": "gene_id_enzyme" }, { "type": "string", "label": "enzyme_name_ncbi-gene" }, { "type": "string", "label": "taxid_enzyme" }, { "type": "string", "label": "organism_name_enzyme" } ], [ "G00221CZ", "P26572-1", "MGAT1", "4245", "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00221CZ", "Q3V5L5-1", "MGAT5B", "146664", "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00221CZ", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00221CZ", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00221CZ", "Q09328-1", "MGAT5", "4249", "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00221CZ", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00221CZ", "Q10469-1", "MGAT2", "4247", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00221CZ", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00221CZ", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00221CZ", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00272VU", "Q9Y231-1", "FUT9", "10690", "fucosyltransferase 9", "9606", "Homo sapiens" ], [ "G00272VU", "P15291-1", "B4GALT1", "2683", "beta-1,4-galactosyltransferase 1", "9606", "Homo sapiens" ], [ "G00272VU", "P22083-1", "FUT4", "2526", "fucosyltransferase 4", "9606", "Homo sapiens" ], [ "G00272VU", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00272VU", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00272VU", "O60512-1", "B4GALT3", "8703", "beta-1,4-galactosyltransferase 3", "9606", "Homo sapiens" ], [ "G00272VU", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00272VU", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00272VU", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00272VU", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00272VU", "Q9BYC5-1", "FUT8", "2530", "fucosyltransferase 8", "9606", "Homo sapiens" ], [ "G00272VU", "O60909-1", "B4GALT2", "8704", "beta-1,4-galactosyltransferase 2", "9606", "Homo sapiens" ], [ "G00279YF", "P26572-1", "MGAT1", "4245", "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00279YF", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00279YF", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00279YF", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00279YF", "Q10469-1", "MGAT2", "4247", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00279YF", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00279YF", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00279YF", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00320ZP", "P26572-1", "MGAT1", "4245", "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00320ZP", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00320ZP", "Q10469-1", "MGAT2", "4247", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00320ZP", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00320ZP", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00361YF", "Q09327-1", "MGAT3", "4248", "mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00361YF", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00361YF", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00361YF", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00361YF", "Q10469-1", "MGAT2", "4247", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00361YF", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00361YF", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00361YF", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00395TQ", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00395TQ", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00395TQ", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00395TQ", "Q9BYC5-1", "FUT8", "2530", "fucosyltransferase 8", "9606", "Homo sapiens" ], [ "G00413UF", "P15291-1", "B4GALT1", "2683", "beta-1,4-galactosyltransferase 1", "9606", "Homo sapiens" ], [ "G00413UF", "P26572-1", "MGAT1", "4245", "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00413UF", "P15907-1", "ST6GAL1", "6480", "ST6 beta-galactoside alpha-2,6-sialyltransferase 1", "9606", "Homo sapiens" ], [ "G00413UF", "Q96JF0-1", "ST6GAL2", "84620", "ST6 beta-galactoside alpha-2,6-sialyltransferase 2", "9606", "Homo sapiens" ], [ "G00413UF", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00413UF", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00413UF", "O60512-1", "B4GALT3", "8703", "beta-1,4-galactosyltransferase 3", "9606", "Homo sapiens" ], [ "G00413UF", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00413UF", "Q10469-1", "MGAT2", "4247", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00413UF", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00413UF", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00413UF", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00413UF", "O60909-1", "B4GALT2", "8704", "beta-1,4-galactosyltransferase 2", "9606", "Homo sapiens" ], [ "G00432WV", "Q9Y231-1", "FUT9", "10690", "fucosyltransferase 9", "9606", "Homo sapiens" ], [ "G00432WV", "P15291-1", "B4GALT1", "2683", "beta-1,4-galactosyltransferase 1", "9606", "Homo sapiens" ], [ "G00432WV", "P26572-1", "MGAT1", "4245", "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00432WV", "P22083-1", "FUT4", "2526", "fucosyltransferase 4", "9606", "Homo sapiens" ], [ "G00432WV", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00432WV", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00432WV", "O60512-1", "B4GALT3", "8703", "beta-1,4-galactosyltransferase 3", "9606", "Homo sapiens" ], [ "G00432WV", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00432WV", "Q10469-1", "MGAT2", "4247", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00432WV", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00432WV", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00432WV", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00432WV", "O60909-1", "B4GALT2", "8704", "beta-1,4-galactosyltransferase 2", "9606", "Homo sapiens" ], [ "G00469BS", "P26572-1", "MGAT1", "4245", "mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "9606", "Homo sapiens" ], [ "G00469BS", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00469BS", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00469BS", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00469BS", "Q9BYC5-1", "FUT8", "2530", "fucosyltransferase 8", "9606", "Homo sapiens" ], [ "G00492CQ", "Q9UQ53-1", "MGAT4B", "11282", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "9606", "Homo sapiens" ], [ "G00492CQ", "Q9UM21-1", "MGAT4A", "11320", "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "9606", "Homo sapiens" ], [ "G00492CQ", "Q9BT22-1", "ALG1", "56052", "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase", "9606", "Homo sapiens" ], [ "G00492CQ", "Q96F25-1", "ALG14", "199857", "ALG14, UDP-N-acetylglucosaminyltransferase subunit", "9606", "Homo sapiens" ], [ "G00492CQ", "Q9UBM8-1", "MGAT4C", "25834", "MGAT4 family member C", "9606", "Homo sapiens" ], [ "G00492CQ", "Q9H553-1", "ALG2", "85365", "ALG2, alpha-1,3/1,6-mannosyltransferase", "9606", "Homo sapiens" ] ] }, "readme": "Name\n - Enzyme Mapping (Human Proteins)\n\nVersion\n - 1.0.13\n\nCreated on\n - 2019-01-23T17:21:05.928353\n\nModified on\n - 2019-04-25T17:17:08.999021\n\nCreated by\n - Rahi Navelkar [rsn13@gwu.edu], Jeet Vora [jeetvora@gwu.edu]\n\nAuthors\n - William York [will@ccrc.uga.edu], Alison V Nairn [avnairn@ccrc.uga.edu], Nathan Edwards [nje5@georgetown.edu], Brian Fochtman [bfochtman@email.gwu.edu], Rahul Sethi [rahulsethi80@gwu.edu]\n\nChecksum\n - \n\nUsability Domain\n - List of Glycans identified by GlyTouCan Accessions with information on the human[taxid:9606] proteins involved in the synthesis of the glycan (inferred via orthology).\n\nDescription Domain\n Keywords\n - GlyTouCan\n - Glycan\n - Enzyme\n - Synthesis\n - Ortholog\n\n Pipeline Steps\n - Step-1: The input file was downloaded from the source link and the 'Enzyme:UniProtAccession' column was mapped to canonical accessions using a python script [ac2canonical.py]\n - Step-1: The mouse protein accessions (UniProt) were mapped to human protein accessions(UniProt) using ortholog file (protein_ortholog.csv)\n - Step-1: The mouse protein accessions (UniProt) were mapped to the NCBI Gene Id's and HGNC label using input files.\n - Step-1: The gene id's were mapped to 'Full_name_from_nomenclature_authority' (Enzyme:Description) from input file (Homo_sapiens.gene_info).\n\nExecution Domain\n Scripts - https://github.com/glygener/glygen-backend/blob/master/integration/ \n - https://github.com/glygener/glygen-backend/blob/master/integration/ \n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: gtc2enz.txt\n URI: https://data.glygen.org/ln2data/releases/data/v-1.0.13/source/gtc2enz.txt\n Name: mouse_protein_ortholog.csv\n URI: https://data.glygen.org/ln2data/releases/data/v-1.0.13/mouse_protein_ortholog.csv\n Name: https://data.glygen.org/ln2data/releases/data/v-1.0.13/source/Homo_sapiens.gene_info.gz\n URI: Homo_sapiens.gene_info\n Name: human_protein_xref_hgnc.csv\n URI: https://data.glygen.org/ln2data/releases/data/v-1.0.13/reviewed/human_protein_xref_hgnc.csv\n Name: human_protein_xref_geneid.csv\n URI: https://data.glygen.org/ln2data/releases/data/v-1.0.13/reviewed/human_protein_xref_geneid.csv\n Output Subdomain\n Name: human_glycan_enzyme.csv\n URI: https://data.glygen.org/ln2data/releases/data/v-1.0.13/reviewed/human_glycan_enzyme.csv\n Name: human_glycan_enzyme.stat.csv\n URI: https://data.glygen.org/ln2data/releases/data/v-1.0.13/reviewed/human_glycan_enzyme.stat.csv\n\nFields\n Name: \"glytoucan_ac\"\n Description: \"\"\n Unique Values: \"2746\"\n Name: \"gene_id_enzyme\"\n Description: \"NCBI Gene Identifier for the gene of the enzyme\"\n Unique Values: \"38\"\n Name: \"Name of the organism that is the source of the enzyme\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"uniprotkb_canonical_ac_enzyme\"\n Description: \"Canonical Accession assigned to the enzyme in the UniProtKB database\"\n Unique Values: \"38\"\n Name: \"enzyme_name_ncbi-gene\"\n Description: \"\"\n Unique Values: \"38\"\n Name: \"taxid_enzyme\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"gene_name_enzyme\"\n Description: \"\"\n Unique Values: \"38\"", "downloadurl": "/ln2data/releases/data/v-1.0.13/reviewed/human_glycan_enzyme.csv" }