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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q92392-1", "uniprot_ac": "Q92392", "uniprot_id": "YO11A_YEAST", "mass": { "chemical_mass": 49005.0, "monoisotopic_mass": 49005.0 }, "refseq": { "ac": "NP_058182", "name": "gag protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058182" }, "gene_names": [ { "name": "TY1A-OL", "type": "recommended", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ] }, { "name": "HRA440", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ] }, { "name": "YOLWTy1-1 GAG", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ] } ], "protein_names": [ { "name": "Transposon Ty1-OL Gag polyprotein", "type": "recommended", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "Gag-p45", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "Gag-p49", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "TY1A", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "TYA", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "Transposon Ty1 protein A", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "gag protein", "type": "synonym", "evidence": [ { "id": "NP_058182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058182" } ] }, { "name": "p54", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] }, { "name": "p58", "type": "synonym", "evidence": [ { "id": "Q92392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA also has nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "gene": [ { "name": "TY1A-OL", "url": "https://www.uniprot.org/uniprotkb/Q92392", "locus": {} } ], "crossref": [ { "id": "SGD:S000007349", "url": "https://alliancegenome.org/gene/SGD:S000007349", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q92392", "url": "https://alphafold.ebi.ac.uk/entry/Q92392", "database": "AlphaFoldDB", "categories": [] }, { "id": "854048", "url": "https://www.ncbi.nlm.nih.gov/gene/854048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q92392", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q92392*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR015820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YOL103W-A", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YOL103W-A", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q92392", "url": "https://oglcnac.org/atlas/detail/Q92392", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "Q92392", "url": "https://www.orthodb.org/?gene=Q92392", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF01021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_058182", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_058182", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000007349", "url": "https://www.yeastgenome.org/locus/S000007349", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q92392-1", "url": "https://www.uniprot.org/uniprotkb/Q92392-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESQQLSNYPQISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIINRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY", "length": 440, "header": "sp|Q92392-1|YO11A_YEAST Isoform 1 of Transposon Ty1-OL Gag polyprotein OS=Saccharomyces cerevisiae S288C OX=559292 GN=TY1A-OL PE=2 SV=1 CANONICAL=Q92392-1" }, "isoforms": [ { "isoform_ac": "Q92392-1", "url": "https://www.uniprot.org/uniprotkb/Q92392/entry#Q92392-1", "sequence": { "sequence": "MESQQLSNYPQISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIINRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY", "length": 440, "header": "sp|Q92392-1|YO11A_YEAST Isoform 1 of Transposon Ty1-OL Gag polyprotein OS=Saccharomyces cerevisiae S288C OX=559292 GN=TY1A-OL PE=2 SV=1 CANONICAL=Q92392-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "GLY_001160", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001160" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 420, "start_aa": "Ser", "end_pos": 420, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser420", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q92392", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q92392" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 421, "start_aa": "Thr", "end_pos": 421, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr421", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q92392", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q92392" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 422, "start_aa": "Thr", "end_pos": 422, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr422", "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q92392", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q92392" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33229814", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33229814" }, { "id": "Q92392", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q92392" } ], "filter_code": "00000000000000000000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [ { "start_pos": 416, "end_pos": 416, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "site_lbl": "Ser416" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "Differential effects of chromatin and Gcn4 on the 50-fold range of expression among individual yeast Ty1 retrotransposons.", "journal": "Mol. Cell. Biol.", "date": "2002", "authors": "Morillon Antonin, B\u00e9nard Lionel, Springer Mathias, Lesage Pascale", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "reference": [ { "type": "PubMed", "id": "11884596", "url": "https://glygen.org/publication/PubMed/11884596" } ] }, { "title": "Happy together: the life and times of Ty retrotransposons and their hosts.", "journal": "Cytogenet. Genome Res.", "date": "2005", "authors": "Lesage P, Todeschini A L", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "reference": [ { "type": "PubMed", "id": "16093660", "url": "https://glygen.org/publication/PubMed/16093660" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT.", "journal": "The Journal of general and applied microbiology", "date": "2021-04-16", "authors": "Li Feng, Yang Ganglong, Tachikawa Hiroyuki, Shao Kankai, Yang Yan, Gao Xiao-Dong, Nakanishi Hideki", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q92392", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q92392" }, { "database": "O-GlcNAc Atlas", "id": "Q92392", "url": "https://oglcnac.org/atlas/detail/Q92392" } ], "reference": [ { "type": "PubMed", "id": "33229814", "url": "https://glygen.org/publication/PubMed/33229814" } ] }, { "title": "Sequence analysis of a 44 kb DNA fragment of yeast chromosome XV including the Ty1-H3 retrotransposon, the suf1(+) frameshift suppressor gene for tRNA-Gly, the yeast transfer RNA-Thr-1a and a delta element.", "journal": "Yeast", "date": "1995", "authors": "Vandenbol M, Durand P, Portetelle D, Hilger F", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "reference": [ { "type": "PubMed", "id": "7502582", "url": "https://glygen.org/publication/PubMed/7502582" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.", "journal": "Nature", "date": "1997", "authors": "Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn\u00e9 R, Boyer J, Camasses A, Casamayor A, Casas C, Ch\u00e9ret G, Cziepluch C, Daignan-Fornier B, Dang D V, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "reference": [ { "type": "PubMed", "id": "9169874", "url": "https://glygen.org/publication/PubMed/9169874" } ] }, { "title": "Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence.", "journal": "Genome Res.", "date": "1998", "authors": "Kim J M, Vanguri S, Boeke J D, Gabriel A, Voytas D F", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "reference": [ { "type": "PubMed", "id": "9582191", "url": "https://glygen.org/publication/PubMed/9582191" } ] } ], "pathway": [ { "id": "sce:YOL103W-A", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YOL103W-A", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "Q92392", "url": "https://www.uniprot.org/uniprotkb/Q92392" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": 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"monoisotopic_mass": 9572.0 }, "refseq": { "ac": "NP_076878", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076878" }, "gene_names": [], "protein_names": [ { "name": "Putative pelota-like protein YCL001W-B", "type": "recommended", "evidence": [ { "id": "Q96VH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q96VH2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_076878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076878" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q96VH2", "url": "https://www.uniprot.org/uniprotkb/Q96VH2" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q96VH2", "locus": {} } ], "crossref": [ { "id": "SGD:S000007596", "url": "https://alliancegenome.org/gene/SGD:S000007596", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q96VH2", "url": "https://alphafold.ebi.ac.uk/entry/Q96VH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "850356", "url": "https://www.ncbi.nlm.nih.gov/gene/850356", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YCL001W-B", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YCL001W-B", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q96VH2", "url": "https://www.orthodb.org/?gene=Q96VH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10853", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10853", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10853:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10853:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q96VH2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q96VH2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_076878", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076878", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000007596", "url": "https://www.yeastgenome.org/locus/S000007596", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q96VH2", "url": "https://www.uniprot.org/uniprotkb/Q96VH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q96VH2-1", "url": "https://www.uniprot.org/uniprotkb/Q96VH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDFLEHLSKDDNKAWYGAEETERAAKLDAIETLLITDSVLKRNDVKKREKYLDLIENSGNNNGKIFVLSTSKITVSNLTNQQI", "length": 84, "header": "sp|Q96VH2-1|YC01B_YEAST Isoform 1 of Putative pelota-like protein YCL001W-B OS=Saccharomyces cerevisiae S288C OX=559292 GN= PE=3 SV=1 CANONICAL=Q96VH2-1" }, "isoforms": [ { "isoform_ac": "Q96VH2-1", "url": "https://www.uniprot.org/uniprotkb/Q96VH2/entry#Q96VH2-1", "sequence": { "sequence": "MDDFLEHLSKDDNKAWYGAEETERAAKLDAIETLLITDSVLKRNDVKKREKYLDLIENSGNNNGKIFVLSTSKITVSNLTNQQI", "length": 84, "header": "sp|Q96VH2-1|YC01B_YEAST Isoform 1 of Putative pelota-like protein YCL001W-B OS=Saccharomyces cerevisiae S288C OX=559292 GN= PE=3 SV=1 CANONICAL=Q96VH2-1" }, "locus": { "chromosome": "III", "start_pos": 113770, "end_pos": 114024, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YCL001W-B_mRNA", "url": "https://www.ensemblgenomes.org/id/YCL001W-B_mRNA" }, { "database": "Ensembl Peptide", "id": "YCL001W-B", "url": "https://www.ensemblgenomes.org/id/YCL001W-B" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited.", "journal": "FEBS Lett.", "date": "2000", "authors": "Blandin G, Durrens P, Tekaia F, Aigle M, Bolotin-Fukuhara M, Bon E, Casar\u00e9gola S, de Montigny J, Gaillardin C, L\u00e9pingle A, Llorente B, Malpertuy A, Neuv\u00e9glise C, Ozier-Kalogeropoulos O, Perrin A, Potier S, Souciet J, Talla E, Toffano-Nioche C, W\u00e9solowski-Louvel M, Marck C, Dujon B", "evidence": [ { "database": "UniProtKB", "id": "Q96VH2", "url": "https://www.uniprot.org/uniprotkb/Q96VH2" } ], "reference": [ { "type": "PubMed", "id": "11152879", "url": "https://glygen.org/publication/PubMed/11152879" } ] }, { "title": "The complete DNA sequence of yeast chromosome III.", "journal": "Nature", "date": "1992", "authors": "Oliver S G, van der Aart Q J, Agostoni-Carbone M L, Aigle M, Alberghina L, Alexandraki D, Antoine G, Anwar R, Ballesta J P, Benit P", "evidence": [ { "database": "UniProtKB", "id": "Q96VH2", "url": "https://www.uniprot.org/uniprotkb/Q96VH2" } ], "reference": [ { "type": "PubMed", "id": "1574125", "url": "https://glygen.org/publication/PubMed/1574125" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q96VH2", "url": "https://www.uniprot.org/uniprotkb/Q96VH2" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] } ], "pathway": [ { "id": "sce:YCL001W-B", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YCL001W-B", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P33309-1", "protein_name": "Protein DOM34", 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"id": "HGNC:8829", "url": "https://alliancegenome.org/gene/HGNC:8829#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P48612-1", "protein_name": "Protein pelota", "gene_name": "pelo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLGKYVDKGMQGNVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTLTIAVESIDFDTQACVLRLKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACDPTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRKRKGSVQQHEKGLAKFYEQVMQSILRHVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDPAVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSLRKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDDDDEDGAAGGVADSDSD", "length": 395 }, "evidence": [ { "id": "RGD:1359591", "url": "https://alliancegenome.org/gene/RGD:1359591#orthology", "database": "AGR" }, { "id": "MGI:2145154", "url": "https://alliancegenome.org/gene/MGI:2145154#orthology", "database": "AGR" }, { "id": "FB:FBgn0011207", "url": "https://alliancegenome.org/gene/FB:FBgn0011207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1074", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1074#orthology", "database": "AGR" }, { "id": "HGNC:8829", "url": "https://alliancegenome.org/gene/HGNC:8829#orthology", "database": "AGR" }, { "id": "SGD:S000007596", "url": "https://alliancegenome.org/gene/SGD:S000007596#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5XIP1-1", "protein_name": "Protein pelota homolog", "gene_name": "Pelo", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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isopropyl (N-3-chloro-phenyl)-carbamate (IPCPC) and guanosine 5'-O-(2-thiodiphosphate).", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247#function" }, { "database": "PubMed", "id": "10407277", "url": "https://glygen.org/publication/PubMed/10407277" }, { "database": "PubMed", "id": "21070969", "url": "https://glygen.org/publication/PubMed/21070969" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "gene": [ { "name": "DUF1", "url": "https://www.uniprot.org/uniprotkb/Q99247", "locus": { "chromosome": "XV", "start_pos": 155287, "end_pos": 158637, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "YOL087C", "url": "https://www.ensemblgenomes.org/id/YOL087C" } ] } } ], "crossref": [ { "id": "SGD:S000005447", "url": "https://alliancegenome.org/gene/SGD:S000005447", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q99247", "url": "https://alphafold.ebi.ac.uk/entry/Q99247", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "854066", "url": "https://www.ncbi.nlm.nih.gov/gene/854066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q99247", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q99247*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YOL087C", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YOL087C", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDIVSCE", "url": "https://omabrowser.org/oma/group/WDIVSCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q99247", "url": "https://www.orthodb.org/?gene=Q99247", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19862", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19862", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19862:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19862:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q99247", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q99247", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_014554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99247-1", "url": "https://www.uniprot.org/uniprotkb/Q99247-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQLTVSYGLISPDYCTSQDAHILPITKILYPDIPGKNYFLTSGRDGSIILHKNTQLSNEPETAATTIKNDAIRMQVHSDWASDLIHVNMKNSDPSAGDTFISVSHDFSIVLISVNAQLTTWDKKIIGDHDDYIKCIVPIHYEMSNDYELEEQEGGPDNVHDGINNGIVVDEQNNFLFVTGGLDRKIKLWCLSSGPEKMATLLHTFDNAQSNDTGSIYSMSPIIPKYSFDDNQTSRPFDFVAGDCNGDLIFYSCKYRKEVIRIQNAHRTNIKVVRTLDDSTRLISTSSDGVINVWDLNCRHDQTTGALQLPKKIGSWSWDSSIWCVQGTSLDKLYFGDSQGNVMRANLSSYEDAKLTRIFKPDHHHHHHHHHEHEEQNISTTDAKVKKYGGILDIALLPNEKLLFSFCTDSNLNVLDLTNNHFSVNEGGFALTRSSLLTNRRHVITENTKGQMQRWDIVSCELLNTFDSSEGSFDDIVMKYTSKEILSHWCTVSVKVGMLFVKINPKFLKTEVYGSALKDYQVVNNIEINSDERYNLGKIVINSLFNEFISYEVQKDKLLRKKIFSLKKKDLTNSLTLDTGYNSESKKNNKDKKRKSTFKISSTLSIGNTNSSGTPPNSAPATPVMAETIVLEEQPLLQSASDKAIDDSLELVQPLPASKKPYFRTQSSGSLLSRKFKSFRSTSGRATTGLNTPEEPKGILPDTPHVINDDSAFPQAINTTQQSKDATPESMLWNHPFKLEQKLSAISSQDLPSNNTHNKLRSSENSRANSTSTLEGNEKKKPEFMPDLLEQIQESYKQQYMNTSSLKYLTKRLPVTKIIKASSCPIIRVKSATLVLVHLWKEGSCGGRVLFSTLLPPSHVDNETVSGGKENSKPPDDEEVDLQAVDDDKLGKYDLIDGELGSRLNRRQIFEQLEENLPYWFAKALFRDIKTVEEQPKLNFLIMPWSSVGGSEAAGNENKKKFISASDTTESSGNDSSDSSLGNGNEAVSPSTQQQFHNMLKFGRPKTSEQELNPTDLPRISEANVKLVAPGMIRVKKIKLYVADRFETKTPEMKAKMEPSLWLDLLCRGQVLDNDMTLNTVRTLYWKSQGDIVLEYRRKVHNSPLVHEVNGNEGK", "length": 1116, "header": "sp|Q99247-1|DUF1_YEAST Isoform 1 of DUB-associated factor 1 OS=Saccharomyces cerevisiae S288C OX=559292 GN=DUF1 PE=1 SV=1 CANONICAL=Q99247-1" }, "isoforms": [ { "isoform_ac": "Q99247-1", "url": "https://www.uniprot.org/uniprotkb/Q99247/entry#Q99247-1", "sequence": { "sequence": "MNQLTVSYGLISPDYCTSQDAHILPITKILYPDIPGKNYFLTSGRDGSIILHKNTQLSNEPETAATTIKNDAIRMQVHSDWASDLIHVNMKNSDPSAGDTFISVSHDFSIVLISVNAQLTTWDKKIIGDHDDYIKCIVPIHYEMSNDYELEEQEGGPDNVHDGINNGIVVDEQNNFLFVTGGLDRKIKLWCLSSGPEKMATLLHTFDNAQSNDTGSIYSMSPIIPKYSFDDNQTSRPFDFVAGDCNGDLIFYSCKYRKEVIRIQNAHRTNIKVVRTLDDSTRLISTSSDGVINVWDLNCRHDQTTGALQLPKKIGSWSWDSSIWCVQGTSLDKLYFGDSQGNVMRANLSSYEDAKLTRIFKPDHHHHHHHHHEHEEQNISTTDAKVKKYGGILDIALLPNEKLLFSFCTDSNLNVLDLTNNHFSVNEGGFALTRSSLLTNRRHVITENTKGQMQRWDIVSCELLNTFDSSEGSFDDIVMKYTSKEILSHWCTVSVKVGMLFVKINPKFLKTEVYGSALKDYQVVNNIEINSDERYNLGKIVINSLFNEFISYEVQKDKLLRKKIFSLKKKDLTNSLTLDTGYNSESKKNNKDKKRKSTFKISSTLSIGNTNSSGTPPNSAPATPVMAETIVLEEQPLLQSASDKAIDDSLELVQPLPASKKPYFRTQSSGSLLSRKFKSFRSTSGRATTGLNTPEEPKGILPDTPHVINDDSAFPQAINTTQQSKDATPESMLWNHPFKLEQKLSAISSQDLPSNNTHNKLRSSENSRANSTSTLEGNEKKKPEFMPDLLEQIQESYKQQYMNTSSLKYLTKRLPVTKIIKASSCPIIRVKSATLVLVHLWKEGSCGGRVLFSTLLPPSHVDNETVSGGKENSKPPDDEEVDLQAVDDDKLGKYDLIDGELGSRLNRRQIFEQLEENLPYWFAKALFRDIKTVEEQPKLNFLIMPWSSVGGSEAAGNENKKKFISASDTTESSGNDSSDSSLGNGNEAVSPSTQQQFHNMLKFGRPKTSEQELNPTDLPRISEANVKLVAPGMIRVKKIKLYVADRFETKTPEMKAKMEPSLWLDLLCRGQVLDNDMTLNTVRTLYWKSQGDIVLEYRRKVHNSPLVHEVNGNEGK", "length": 1116, "header": "sp|Q99247-1|DUF1_YEAST Isoform 1 of DUB-associated factor 1 OS=Saccharomyces cerevisiae S288C OX=559292 GN=DUF1 PE=1 SV=1 CANONICAL=Q99247-1" }, "locus": { "chromosome": "XV", "start_pos": 155287, "end_pos": 158637, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YOL087C_mRNA", "url": "https://www.ensemblgenomes.org/id/YOL087C_mRNA" }, { "database": "Ensembl Peptide", "id": "YOL087C", "url": "https://www.ensemblgenomes.org/id/YOL087C" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 1008, "end_pos": 1008, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr1008" }, { "start_pos": 1009, "end_pos": 1009, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser1009" }, { "start_pos": 1104, "end_pos": 1104, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser1104" }, { "start_pos": 584, "end_pos": 584, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser584" }, { "start_pos": 649, "end_pos": 649, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" }, { "database": "PubMed", "id": "34965436", "url": "https://glygen.org/publication/PubMed/34965436" } ], "site_lbl": "Ser649" }, { "start_pos": 666, "end_pos": 666, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr666" }, { "start_pos": 668, "end_pos": 668, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser668" }, { "start_pos": 669, "end_pos": 669, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser669" }, { "start_pos": 671, "end_pos": 671, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser671" }, { "start_pos": 674, "end_pos": 674, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser674" }, { "start_pos": 688, "end_pos": 688, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" } ], "site_lbl": "Thr688" }, { "start_pos": 693, "end_pos": 693, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" }, { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr693" }, { "start_pos": 724, "end_pos": 724, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005447", "url": "https://www.yeastgenome.org/locus/S000005447" }, { "database": "iPTMnet", "id": "Q99247", 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"keywords": [], "publication": [ { "title": "Chemotyping of yeast mutants using robotics.", "journal": "Yeast (Chichester, England)", "date": "1999-07", "authors": "Rieger K J, El-Alama M, Stein G, Bradshaw C, Slonimski P P, Maundrell K", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "reference": [ { "type": "PubMed", "id": "10407277", "url": "https://glygen.org/publication/PubMed/10407277" } ] }, { "title": "Global analysis of protein localization in budding yeast.", "journal": "Nature", "date": "2003", "authors": "Huh Won-Ki, Falvo James V, Gerke Luke C, Carroll Adam S, Howson Russell W, Weissman Jonathan S, O'Shea Erin K", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "reference": [ { "type": "PubMed", "id": "14562095", "url": "https://glygen.org/publication/PubMed/14562095" } ] }, { "title": "Global analysis of protein expression in yeast.", "journal": 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Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Quantitative proteomics identifies unanticipated regulators of nitrogen- and glucose starvation.", "journal": "Molecular bioSystems", "date": "2014-08", "authors": "R\u00f8dk\u00e6r Steven V, Pultz Dennis, Brusch Michelle, Bennetzen Martin V, Falkenby Lasse G, Andersen Jens S, F\u00e6rgeman Nils J", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" } ], "reference": [ { "type": "PubMed", "id": "24909858", "url": "https://glygen.org/publication/PubMed/24909858" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "Q99247", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99247" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": 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"MLTHKTCQARKKMQVSFVIRDAEEKQHRNGVNALQLDANNGKLYSAGRDAIIRVWNTRTDSSEKYIQSMEHHNDWVNDIVLCCNGRNLISASCDTTVKVWNAQKGFCMSTLRTHRDYVQALAYAKDREQVASAGLDKAIFLWDVNTLTALTASNNTVTTSSLTGSKDSIYSLAMNPSGTVIVSGSTENILRIWDPRTCMRRMKLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRCVQTIHVHKEGVWSLLMSENFQYIISGSRDRNIIVTEMRNPSNKTLVCEEQAPVLSLGYNIDKTGVWATTWNSDIRCWKLPMYDRCTLNSSGGMDAQWTQGGTEVACIKGGAAIKECAVLNDKRYIITKDSQDQVVVYDVLRVVKKEQLGAVDFEAEVKKRNKQVYIPNWFTVDLKTGMPTIVLGQEEVDCFSAWVSIEAGLPECVDPTTEIKINYGKLLLEALLEYWTPPHSIPPNEMEPDMHGNGYFQVPKHTPVIFSEVGGRTVCRLLVRDAAGDSESTLLHETAPQWVTDVVIEKNIPKFLKIPFFLQPHPQMTKPERTKKDRLVANEFIQCRKVCEHVLEKVLNAETTPSGGNANNSLQNSQSDANSEGSQLPAEERIELWCNDVVVDPNMDLRTVRHFIWKQSTDLTFQYKTKQNFNYDGK", "length": 668 }, "evidence": [ { "id": "RGD:1309702", "url": "https://alliancegenome.org/gene/RGD:1309702#orthology", "database": "AGR" }, { "id": "MGI:1914811", "url": "https://alliancegenome.org/gene/MGI:1914811#orthology", "database": "AGR" }, { "id": "HGNC:30914", "url": "https://alliancegenome.org/gene/HGNC:30914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6622", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6622#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-55#orthology", "database": "AGR" }, { "id": "FB:FBgn0033607", "url": "https://alliancegenome.org/gene/FB:FBgn0033607#orthology", "database": "AGR" }, { "id": "SGD:S000005447", "url": "https://alliancegenome.org/gene/SGD:S000005447#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6PFM9-1", "protein_name": "WD repeat-containing protein 48", "gene_name": "wdr48", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATLHRQNAAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIILCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHIYSGGRDRKIYCTDLRNPDMRVLICEEKAPVLRMELDRSADPPQSIWVSTTKSFVNKWSLKAMHNFRASGDYDNDCSAPLTPLCTQPEQVIKGGTSIVQCHILNDKRHILTKDTNNSVAFWDVLKACKGEDLGKVDFDEEVKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVAAKDAGFTSPDGSDPKLNLGGLLLQALLEFWPRTHINPMEEEENELNHVNGEQESRIQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHSSSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDTESQATSSSANDKPGEQEKEEDVSVMAEEKIELMCLDQVLDPNMDLRTVKHFIWKSGGDLTIHYRQKST", "length": 677 }, "evidence": [ { "id": "RGD:1309702", "url": "https://alliancegenome.org/gene/RGD:1309702#orthology", "database": "AGR" }, { "id": "MGI:1914811", "url": "https://alliancegenome.org/gene/MGI:1914811#orthology", "database": "AGR" }, { "id": "HGNC:30914", "url": "https://alliancegenome.org/gene/HGNC:30914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6622", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6622#orthology", "database": "AGR" }, { "id": "FB:FBgn0033607", "url": "https://alliancegenome.org/gene/FB:FBgn0033607#orthology", "database": "AGR" }, { "id": "SGD:S000005447", "url": "https://alliancegenome.org/gene/SGD:S000005447#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BH57-1", "protein_name": "WD repeat-containing protein 48", "gene_name": "Wdr48", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVTPMDEEENEVNHVSGGQESRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETEAMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST", "length": 676 }, "evidence": [ { "id": "RGD:1309702", "url": "https://alliancegenome.org/gene/RGD:1309702#orthology", "database": "AGR" }, { "id": "MGI:1914811", "url": "https://alliancegenome.org/gene/MGI:1914811#orthology", "database": "AGR" }, { "id": "HGNC:30914", "url": "https://alliancegenome.org/gene/HGNC:30914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6622", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6622#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-55#orthology", "database": "AGR" }, { "id": "FB:FBgn0033607", "url": "https://alliancegenome.org/gene/FB:FBgn0033607#orthology", "database": "AGR" }, { "id": "SGD:S000005447", "url": "https://alliancegenome.org/gene/SGD:S000005447#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAF3-1", "protein_name": "WD repeat-containing protein 48", "gene_name": "WDR48", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST", "length": 677 }, "evidence": [ { "id": "RGD:1309702", "url": "https://alliancegenome.org/gene/RGD:1309702#orthology", "database": "AGR" }, { "id": "MGI:1914811", "url": "https://alliancegenome.org/gene/MGI:1914811#orthology", "database": "AGR" }, { "id": "HGNC:30914", "url": "https://alliancegenome.org/gene/HGNC:30914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6622", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6622#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-55#orthology", "database": "AGR" }, { "id": "FB:FBgn0033607", "url": "https://alliancegenome.org/gene/FB:FBgn0033607#orthology", "database": "AGR" }, { "id": "SGD:S000005447", "url": "https://alliancegenome.org/gene/SGD:S000005447#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q99247", "url": "https://www.uniprot.org/uniprotkb/Q99247" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q99247-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1116, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q99247-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q99247" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 584, 649, 666, 668, 669, 671, 674, 688, 693, 724, 728, 745, 748, 749, 763, 767, 771, 772, 773, 774, 832, 1008, 1009, 1104 ], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 755, "end_pos": 757 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 863, "end_pos": 865 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 24 }, { "field": "total_sites", "count": 24 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q99248-1", "uniprot_ac": "Q99248", "uniprot_id": "YO019_YEAST", "mass": { "chemical_mass": 83366.0, "monoisotopic_mass": 83366.0 }, "refseq": { "ac": "NP_014662", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014662" }, "gene_names": [ { "name": "OR26.09", "type": "synonym", "evidence": [ { "id": "Q99248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99248" } ] } ], "protein_names": [ { "name": "Uncharacterized protein YOR019W", "type": "recommended", "evidence": [ { "id": "Q99248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99248/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_014662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014662" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99248", "url": "https://www.uniprot.org/uniprotkb/Q99248" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q99248", "locus": {} } ], "crossref": [ { "id": "SGD:S000005545", "url": "https://alliancegenome.org/gene/SGD:S000005545", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q99248", "url": "https://alphafold.ebi.ac.uk/entry/Q99248", "database": "AlphaFoldDB", "categories": [] }, { "id": "854184", "url": "https://www.ncbi.nlm.nih.gov/gene/854184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "sce:YOR019W", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YOR019W", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRRTENL", "url": "https://omabrowser.org/oma/group/WRRTENL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q99248", "url": "https://www.orthodb.org/?gene=Q99248", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PR:Q99248", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q99248", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_014662", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014662", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000005545", "url": "https://www.yeastgenome.org/locus/S000005545", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q99248", "url": "https://www.uniprot.org/uniprotkb/Q99248", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99248-1", "url": "https://www.uniprot.org/uniprotkb/Q99248-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISVCPQNDLQKCYRSLTFDVPGQQFEERNEQNLKKRAKKKGSFQPSVAFDTVPSTAGYSSIDDSREGFKGVPVPNYYTMEECYDDETDSFSPNLQYYLRDTFQSSPFLNTRKENKSESSSFPMRSSKLLEKNSDIKKYFLVSKNGKIVRRDYPSTPVIVNETLMINRFEKNWIKLWRQRKLQINERLNDKKKWFTYPELIFSEERIKPLYRGDDSAPCTKEQKRKHKILQQKVGYPNNPKTIVCHINGKKHTWVALDWTVYKFARNLDHIVVITTLPKMISNRKKTAKDDTEWAPGYQKEVIDQKLNDIFDYILQLVKVVKISVKITLEIIVGKIKKSLVDVINVHTPDFLVLATLKHERNENLITYKSKKLTDVFPVSYPIPTFVVPSKRMYSFELNLQREVNEHYVSKNHMKHEHTDVESMSSSMFKKNTISDISSHISVDSYAEDFKRQGYIKKQFNTSNDSIPRKLTGLAQHSRRKITGDIEKLQDDEKDRECTKEKLLLKKIDIIIRESLKSSLAIETLPGKNVSQSSHGDQISSFKNALIGNGSKNTKFRKSLIPYSSSEEQNTTTTIKLSSSPTSQIKFATSVKHKDGRAALGKARNLPDIRHSISFDKENSFDPSDKSSSVDNSIPLRKVKSAGALRKVKTNDSSSSAGSKKSSSSFSTVNTFTGGGVGIFKVFKSGSSSGNKSSSRRNSSSGDVFESDDRNDKKKKKKKKKKSLFLFGKI", "length": 730, "header": "sp|Q99248-1|YO019_YEAST Isoform 1 of Uncharacterized protein YOR019W OS=Saccharomyces cerevisiae S288C OX=559292 GN= PE=2 SV=1 CANONICAL=Q99248-1" }, "isoforms": [ { "isoform_ac": "Q99248-1", "url": "https://www.uniprot.org/uniprotkb/Q99248/entry#Q99248-1", "sequence": { "sequence": "MISVCPQNDLQKCYRSLTFDVPGQQFEERNEQNLKKRAKKKGSFQPSVAFDTVPSTAGYSSIDDSREGFKGVPVPNYYTMEECYDDETDSFSPNLQYYLRDTFQSSPFLNTRKENKSESSSFPMRSSKLLEKNSDIKKYFLVSKNGKIVRRDYPSTPVIVNETLMINRFEKNWIKLWRQRKLQINERLNDKKKWFTYPELIFSEERIKPLYRGDDSAPCTKEQKRKHKILQQKVGYPNNPKTIVCHINGKKHTWVALDWTVYKFARNLDHIVVITTLPKMISNRKKTAKDDTEWAPGYQKEVIDQKLNDIFDYILQLVKVVKISVKITLEIIVGKIKKSLVDVINVHTPDFLVLATLKHERNENLITYKSKKLTDVFPVSYPIPTFVVPSKRMYSFELNLQREVNEHYVSKNHMKHEHTDVESMSSSMFKKNTISDISSHISVDSYAEDFKRQGYIKKQFNTSNDSIPRKLTGLAQHSRRKITGDIEKLQDDEKDRECTKEKLLLKKIDIIIRESLKSSLAIETLPGKNVSQSSHGDQISSFKNALIGNGSKNTKFRKSLIPYSSSEEQNTTTTIKLSSSPTSQIKFATSVKHKDGRAALGKARNLPDIRHSISFDKENSFDPSDKSSSVDNSIPLRKVKSAGALRKVKTNDSSSSAGSKKSSSSFSTVNTFTGGGVGIFKVFKSGSSSGNKSSSRRNSSSGDVFESDDRNDKKKKKKKKKKSLFLFGKI", "length": 730, "header": "sp|Q99248-1|YO019_YEAST Isoform 1 of Uncharacterized protein YOR019W OS=Saccharomyces cerevisiae S288C 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Beltrao Pedro, Starita Lea, Guo Ailan, Rush John, Fields Stanley, Krogan Nevan J, Vill\u00e9n Judit", "evidence": [ { "database": "iPTMnet", "id": "Q99248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99248" } ], "reference": [ { "type": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q99248", "url": "https://www.uniprot.org/uniprotkb/Q99248" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses.", "journal": "Journal of proteome research", "date": "2020-08-07", "authors": "MacGilvray Matthew E, Shishkova Evgenia, Place Michael, Wagner Ellen R, Coon Joshua J, Gasch Audrey P", "evidence": [ { "database": "iPTMnet", "id": "Q99248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99248" } ], "reference": [ { "type": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ] }, { "title": "Cross-compartment signal propagation in the mitotic exit network.", "journal": "eLife", "date": "2021-01-22", "authors": "Zhou Xiaoxue, Li Wenxue, Liu Yansheng, Amon Angelika", "evidence": [ { "database": "iPTMnet", "id": "Q99248", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99248" } ], "reference": [ { "type": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ] }, { 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"MTHITLGQAIWASVRPIIKIYLIIGVGFGLCKMNILTVQATRSISDIVLTILLPCLSFNKIVANIEDNDIKDVGIICLTSVILFATGLGFAFIVRSVLPVPKRWRGGILAGGMFPNISDLPIAYLQSMDQGFIFTEAEGEKGVANVIIFLAMFLICVFNLGGFRLIENDFHYKGDDDEENTLTNDDSAQQPTQPIEGNSSSSSNQDILKEPNESTVPNSSQASYISEKNKKEKTELSVPKPTHTAPPAIDDRSSNSSAVVSIDSITHSLRTNHVDAQSVSELNDPTYRTRSQPIAYTTESRTSHVHNNRRNSITGSLRSIDMRELPAEGMSDLIREYSNVDQYGRRRKSSISSQGAPSVLQADGTISPNLTRTSTLQRVKTSNLTRIITSDATVSKKDIETSGSSLPKWLQKFPLTKFFVFFLKNCLRPCSMAVILALIIAFIPWVKALFVTTSNTPKIKQAPDNAPALTFIMDFTSYVGAASVPFGLILLGATLGRLKIGKLYPGFWKSAVVLVFLRQCIMPIFGVLWCDRLVKAGWLNWENDKMLLFVTAITWNLPTMTTLIYFTASYTPEDETEPVQMECTSFFLMLQYPLMVVSLPFLVSYFIKVQMKL", "length": 613, "header": "sp|Q99252-1|ECM3_YEAST Isoform 1 of Protein ECM3 OS=Saccharomyces cerevisiae S288C OX=559292 GN=ECM3 PE=1 SV=1 CANONICAL=Q99252-1" }, "isoforms": [ { "isoform_ac": "Q99252-1", "url": "https://www.uniprot.org/uniprotkb/Q99252/entry#Q99252-1", "sequence": { "sequence": "MTHITLGQAIWASVRPIIKIYLIIGVGFGLCKMNILTVQATRSISDIVLTILLPCLSFNKIVANIEDNDIKDVGIICLTSVILFATGLGFAFIVRSVLPVPKRWRGGILAGGMFPNISDLPIAYLQSMDQGFIFTEAEGEKGVANVIIFLAMFLICVFNLGGFRLIENDFHYKGDDDEENTLTNDDSAQQPTQPIEGNSSSSSNQDILKEPNESTVPNSSQASYISEKNKKEKTELSVPKPTHTAPPAIDDRSSNSSAVVSIDSITHSLRTNHVDAQSVSELNDPTYRTRSQPIAYTTESRTSHVHNNRRNSITGSLRSIDMRELPAEGMSDLIREYSNVDQYGRRRKSSISSQGAPSVLQADGTISPNLTRTSTLQRVKTSNLTRIITSDATVSKKDIETSGSSLPKWLQKFPLTKFFVFFLKNCLRPCSMAVILALIIAFIPWVKALFVTTSNTPKIKQAPDNAPALTFIMDFTSYVGAASVPFGLILLGATLGRLKIGKLYPGFWKSAVVLVFLRQCIMPIFGVLWCDRLVKAGWLNWENDKMLLFVTAITWNLPTMTTLIYFTASYTPEDETEPVQMECTSFFLMLQYPLMVVSLPFLVSYFIKVQMKL", "length": 613, "header": "sp|Q99252-1|ECM3_YEAST Isoform 1 of Protein ECM3 OS=Saccharomyces cerevisiae S288C OX=559292 GN=ECM3 PE=1 SV=1 CANONICAL=Q99252-1" }, "locus": { "chromosome": "XV", "start_pos": 495127, "end_pos": 496968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YOR092W_mRNA", "url": "https://www.ensemblgenomes.org/id/YOR092W_mRNA" }, { "database": "Ensembl Peptide", "id": "YOR092W", "url": "https://www.ensemblgenomes.org/id/YOR092W" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 271, "end_pos": 271, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr271" }, { "start_pos": 278, "end_pos": 278, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser278" }, { "start_pos": 280, "end_pos": 280, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser280" }, { "start_pos": 291, "end_pos": 291, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99252", "url": "https://www.uniprot.org/uniprotkb/Q99252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "18407956", "url": "https://glygen.org/publication/PubMed/18407956" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser291" }, { "start_pos": 297, "end_pos": 297, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr297" }, { "start_pos": 298, "end_pos": 298, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Thr298" }, { "start_pos": 303, "end_pos": 303, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" } ], "site_lbl": "Ser303" }, { "start_pos": 312, "end_pos": 312, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser312" }, { "start_pos": 314, "end_pos": 314, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "PubMed", "id": "21126336", "url": "https://glygen.org/publication/PubMed/21126336" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "32597660", "url": "https://glygen.org/publication/PubMed/32597660" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Thr314" }, { "start_pos": 316, "end_pos": 316, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { 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"iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "19684113", "url": "https://glygen.org/publication/PubMed/19684113" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "PubMed", "id": "23749301", "url": "https://glygen.org/publication/PubMed/23749301" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser319" }, { "start_pos": 331, "end_pos": 331, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "33481703", "url": "https://glygen.org/publication/PubMed/33481703" } ], "site_lbl": "Ser331" }, { "start_pos": 337, "end_pos": 337, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005618", "url": "https://www.yeastgenome.org/locus/S000005618" }, { "database": "iPTMnet", "id": "Q99252", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99252" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Tyr337" }, { "start_pos": 338, "end_pos": 338, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99252", "url": "https://www.uniprot.org/uniprotkb/Q99252" }, { "database": "PubMed", "id": "19779198", "url": "https://glygen.org/publication/PubMed/19779198" }, { "database": "iPTMnet", "id": "Q99252", "url": 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"malignant ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian 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"description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MIM:167000", "resource": "MIM", "url": "https://www.omim.org/entry/167000", "name": "Ovarian cancer", "description": "Ovarian cancer" } ], "unlinked_id_list": [ "DOID:2151" ], "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, "evidence": [ { "database": "UniProtKB", "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369" } ], "common_name": "Baker's yeast", "glygen_name": "Yeast", "reference_species": "Saccharomyces cerevisiae S288C [559292]" } ], "gene": [ { "name": "FSH3", "url": "https://www.uniprot.org/uniprotkb/Q99369", "locus": { "chromosome": "XV", "start_pos": 844992, "end_pos": 845792, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "YOR280C", "url": "https://www.ensemblgenomes.org/id/YOR280C" } ] } } ], "crossref": [ { "id": "SGD:S000005806", "url": "https://alliancegenome.org/gene/SGD:S000005806", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q99369", "url": "https://alphafold.ebi.ac.uk/entry/Q99369", "database": "AlphaFoldDB", "categories": [] }, { "id": "854454", "url": "https://www.ncbi.nlm.nih.gov/gene/854454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q99369", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q99369*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "sce:YOR280C", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YOR280C", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEPRGWW", "url": "https://omabrowser.org/oma/group/EEPRGWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q99369", "url": "https://www.orthodb.org/?gene=Q99369", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48070:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48070:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q99369", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q99369", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_014923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_014923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "S000005806", "url": "https://www.yeastgenome.org/locus/S000005806", "database": "SGD", "categories": [ "Organism-specific" ] }, { "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99369-1", "url": "https://www.uniprot.org/uniprotkb/Q99369-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKKKVLMLHGFVQSDKIFSAKTGGLRKNLKKLGYDLYYPCAPHSIDKKALFQSESEKGRDAAKEFNTSATSDEVYGWFFRNPESFNSFQIDQKVFNYLRNYVLENGPFDGVIGFSQGAGLGGYLVTDFNRILNLTDEQQPALKFFISFSGFKLEDQSYQKEYHRIIQVPSLHVRGELDEVVAESRIMALYESWPDNKRTLLVHPGAHFVPNSKPFVSQVCNWIQGITSKEGQEHNAQPEVDRKQFDKPQLEDDLLDMIDSLGKL", "length": 266, "header": "sp|Q99369-1|FSH3_YEAST Isoform 1 of Family of serine hydrolases 3 OS=Saccharomyces cerevisiae S288C OX=559292 GN=FSH3 PE=2 SV=1 CANONICAL=Q99369-1" }, "isoforms": [ { "isoform_ac": "Q99369-1", "url": "https://www.uniprot.org/uniprotkb/Q99369/entry#Q99369-1", "sequence": { "sequence": "MSEKKKVLMLHGFVQSDKIFSAKTGGLRKNLKKLGYDLYYPCAPHSIDKKALFQSESEKGRDAAKEFNTSATSDEVYGWFFRNPESFNSFQIDQKVFNYLRNYVLENGPFDGVIGFSQGAGLGGYLVTDFNRILNLTDEQQPALKFFISFSGFKLEDQSYQKEYHRIIQVPSLHVRGELDEVVAESRIMALYESWPDNKRTLLVHPGAHFVPNSKPFVSQVCNWIQGITSKEGQEHNAQPEVDRKQFDKPQLEDDLLDMIDSLGKL", "length": 266, "header": "sp|Q99369-1|FSH3_YEAST Isoform 1 of Family of serine hydrolases 3 OS=Saccharomyces cerevisiae S288C OX=559292 GN=FSH3 PE=2 SV=1 CANONICAL=Q99369-1" }, "locus": { "chromosome": "XV", "start_pos": 844992, "end_pos": 845792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "YOR280C_mRNA", "url": "https://www.ensemblgenomes.org/id/YOR280C_mRNA" }, { "database": "Ensembl Peptide", "id": "YOR280C", "url": "https://www.ensemblgenomes.org/id/YOR280C" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 57, "end_pos": 57, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "SGD", "id": "S000005806", "url": "https://www.yeastgenome.org/locus/S000005806" }, { "database": "iPTMnet", "id": "Q99369", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99369" }, { "database": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ], "site_lbl": "Ser57" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004-03", "authors": "Baxter Susan M, Rosenblum Jonathan S, Knutson Stacy, Nelson Melanie R, Montimurro Jennifer S, Di Gennaro Jeannine A, Speir Jeffrey A, Burbaum Jonathan J, Fetrow Jacquelyn S", "evidence": [ { "database": "UniProtKB", "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369" } ], "reference": [ { "type": "PubMed", "id": "14645503", "url": "https://glygen.org/publication/PubMed/14645503" } ] }, { "title": "Identification of new genes regulated by the Crt1 transcription factor, an effector of the DNA damage checkpoint pathway in Saccharomyces cerevisiae.", "journal": "J. Biol. Chem.", "date": "2005", "authors": "Zaim Jolanta, Speina Elzbieta, Kierzek Andrzej M", "evidence": [ { "database": "UniProtKB", "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369" } ], "reference": [ { "type": "PubMed", "id": "15494396", "url": "https://glygen.org/publication/PubMed/15494396" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.", "journal": "EMBO reports", "date": "2021-02-03", "authors": "Lanz Michael C, Yugandhar Kumar, Gupta Shagun, Sanford Ethan J, Fa\u00e7a Vitor M, Vega Stephanie, Joiner Aaron M N, Fromme J Christopher, Yu Haiyuan, Smolka Marcus B", "evidence": [ { "database": "iPTMnet", "id": "Q99369", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99369" } ], "reference": [ { "type": "PubMed", "id": "33491328", "url": "https://glygen.org/publication/PubMed/33491328" } ] }, { "title": "DNA sequence analysis of the VPH1-SNF2 region on chromosome XV of Saccharomyces cerevisiae.", "journal": "Yeast", "date": "1996", "authors": "Ch\u00e9ret G, Bernardi A, Sor F", "evidence": [ { "database": "UniProtKB", "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369" } ], "reference": [ { "type": "PubMed", "id": "8896271", "url": "https://glygen.org/publication/PubMed/8896271" } ] }, { "title": "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.", "journal": "Nature", "date": "1997", "authors": "Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn\u00e9 R, Boyer J, Camasses A, Casamayor A, Casas C, Ch\u00e9ret G, Cziepluch C, Daignan-Fornier B, Dang D V, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K", "evidence": [ { "database": "UniProtKB", "id": "Q99369", "url": "https://www.uniprot.org/uniprotkb/Q99369" } ], "reference": [ { "type": "PubMed", "id": "9169874", "url": "https://glygen.org/publication/PubMed/9169874" } ] } ], "pathway": [ { "id": "sce:YOR280C", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:YOR280C", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MHB7-1", "protein_name": "Esterase OVCA2", "gene_name": "Ovca2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAARQPLRVLCLAGFRQSERGFREKTGALRKALRGRAELVCLSGPHPVPEAAAPEGAGPDSGPGAPEEQPRGWWFSEQEADVFYALEEPTACRGLEKALETVAQALDTLGPFDGLLGFSQGAALAAFVCALGQAGDLRFPVPRFLILVSGFWPRGLGFKESILQSPLSLPSLHVFGDTDRIIPPQESMQLASQFLGAVTLTHSGGHFIPAAATQRQAYLKFLDQFAE", "length": 227 }, "evidence": [ { "id": "Q99369", "url": "https://omabrowser.org/oma/group/Q99369/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LFP2-1", "protein_name": "Esterase OVCA2", "gene_name": "Ovca2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "FKQGSSLSSQASSIICVQSIPGPSLPTPKASGCVFPKLCLLPLTLLSSPDSVLFSHLFLGPCSPEEQPRGWWFSEEEADVFSALEEPTVCRGLEAALETVAQALDKLGPFDGLLGFSQGAALAAFVCALGQAGDPRFPLPRFIILVSGFCPRGLDHKEPILQSPISLPSLHVFGDTDRVIPSQESMQLASRFLGAVTLTHSGGHFIPAAASHRQAYLKFLDQFAE", "length": 225 }, "evidence": [ { "id": "HGNC:24203", "url": "https://alliancegenome.org/gene/HGNC:24203#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38777-1", "protein_name": "Family of serine hydrolases 1", "gene_name": "FSH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVQIPKLLFLHGFLQNGKVFSEKSSGIRKLLKKANVQCDYIDAPVLLEKKDLPFEMDDEKWQATLDADVNRAWFYHSEISHELDISEGLKSVVDHIKANGPYDGIVGFSQGAALSSIITNKISELVPDHPQFKVSVVISGYSFTEPDPEHPGELRITEKFRDSFAVKPDMKTKMIFIYGASDQAVPSVRSKYLYDIYLKAQNGNKEKVLAYEHPGGHMVPNKKDIIRPIVEQITSSLQEASE", "length": 243 }, "evidence": [ { "id": "FB:FBgn0038806", "url": "https://alliancegenome.org/gene/FB:FBgn0038806#orthology", "database": "AGR" }, { "id": "MGI:2179725", "url": "https://alliancegenome.org/gene/MGI:2179725#orthology", "database": "AGR" }, { "id": "HGNC:24203", "url": "https://alliancegenome.org/gene/HGNC:24203#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-115#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q05015-1", "protein_name": "Family of serine hydrolases 2", "gene_name": "FSH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTKNVLMLHGLAQSGDYFASKTKGFRAEMEKLGYKLYYPTAPNEFPPADVPDFLGEVIADAPGDGENTGVLAWLENDPSTGGYFIPQTTIDYLHNYVLENGPFAGIVGFSQGAGVAGYLATDFNGLLGLTTEEQPPLEFFMAVSGFRFQPQQYQEQYDLHPISVPSLHVQGELDTITEPAKVQGLYNSCTEDSRTLLMHSGGHFVPNSRGFVRKVAQWLQQLT", "length": 223 }, "evidence": [ { "id": "FB:FBgn0038806", "url": "https://alliancegenome.org/gene/FB:FBgn0038806#orthology", "database": "AGR" }, { "id": "MGI:2179725", "url": "https://alliancegenome.org/gene/MGI:2179725#orthology", "database": "AGR" }, { "id": "HGNC:24203", "url": "https://alliancegenome.org/gene/HGNC:24203#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-115#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3SZ07-1", "protein_name": "Esterase OVCA2", "gene_name": "OVCA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAQPLLRILCLAGFRQSERGFREKTGALRKALRGRAELVCLSGPHPVVDAAGSEGARPDSGPCPPEEQPQGWWFSEQEADVFLALEEPTACRGLEEALETVAQALNKLGPFDGILGFSQGAALAALVCALGQGGDPRFPLPRFVILVSGFCPRGLGLMEPIMQGPLSLPSLHVFGDTDGVIPSQESMQLCSRFDGAVTLTHSGGHFIPAAAPQRQAYLKFLDQFAD", "length": 227 }, "evidence": [ { "id": "Q99369", "url": "https://omabrowser.org/oma/group/Q99369/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q503Y4-1", "protein_name": "Esterase OVCA2", "gene_name": "ovca2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAVPLRILCIHGYRQNGNSFREKTGALRKLLKKQVELVFISAPHQVPAIQEENCGTNQQSQTVSVGDEDQRGWWFSDVQARSFNAKQDCESSLGLEESIEAVKAALKDLGPFSGILGFSQGAALVAMLCALQEQKLEPDFNFRFAILVAGFRSACLEHQRFYEGPVITIPSLHVFGQDDRVIPEEMSRDLLPAFDGAQVLLHPGGHFVPAASSHRQTYQDFLKRFQ", "length": 227 }, "evidence": [ { "id": "FB:FBgn0038806", "url": "https://alliancegenome.org/gene/FB:FBgn0038806#orthology", "database": "AGR" }, { "id": "MGI:2179725", "url": "https://alliancegenome.org/gene/MGI:2179725#orthology", "database": "AGR" }, { "id": "HGNC:24203", "url": "https://alliancegenome.org/gene/HGNC:24203#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-115#orthology", "database": "AGR" }, { "id": "SGD:S000005806", "url": "https://alliancegenome.org/gene/SGD:S000005806#orthology", "database": "AGR" }, { "id": "Q99369", "url": "https://omabrowser.org/oma/group/Q99369/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8WZ82-1", "protein_name": "Esterase OVCA2", "gene_name": "OVCA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQRPLRVLCLAGFRQSERGFREKTGALRKALRGRAELVCLSGPHPVPDPPGPEGARSDFGSCPPEEQPRGWWFSEQEADVFSALEEPAVCRGLEESLGMVAQALNRLGPFDGLLGFSQGAALAALVCALGQAGDPRFPLPRFILLVSGFCPRGIGFKESILQRPLSLPSLHVFGDTDKVIPSQESVQLASQFPGAITLTHSGGHFIPAAAPQRQAYLKFLDQFAE", "length": 227 }, "evidence": [ { "id": "FB:FBgn0038806", "url": "https://alliancegenome.org/gene/FB:FBgn0038806#orthology", "database": "AGR" }, { "id": "MGI:2179725", "url": "https://alliancegenome.org/gene/MGI:2179725#orthology", "database": "AGR" }, { "id": "HGNC:24203", "url": "https://alliancegenome.org/gene/HGNC:24203#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-115#orthology", "database": "AGR" }, { "id": "SGD:S000005806", "url": "https://alliancegenome.org/gene/SGD:S000005806#orthology", "database": "AGR" }, { "id": "Q99369", "url": "https://omabrowser.org/oma/group/Q99369/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { 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"https://www.uniprot.org/uniprotkb/Q99373/entry#names_and_taxonomy" } ] }, { "name": "Pet20p", "type": "synonym", "evidence": [ { "id": "NP_015166", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_015166" } ] }, { "name": "Petite colonies protein 20", "type": "synonym", "evidence": [ { "id": "Q99373", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99373/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for respiratory growth, stability of the mitochondrial genome and for proper assembly or maintenance of mitochondrial proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q99373", "url": "https://www.uniprot.org/uniprotkb/Q99373#function" }, { "database": "PubMed", "id": "16491469", "url": "https://glygen.org/publication/PubMed/16491469" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Saccharomyces cerevisiae S288C", "taxid": 559292, 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[ "Protein" ] } ], "sequence": { "sequence": "MLMLLMMILTNNKVFMETLYYYLMFNFQLMSPFGVPVPGPAPETKDIKNLYESIMNNYINILNKYTININKDNINKLKFLDNYTEEEKGYYLSGLFEGDGNIYTRCFSITFSLEDVLLANYLCTYFKIGHITAKYNFNKELTAVKWNIMKKKEQEVFMNYINGKLLTYKRYDQYFKYNFNNRLNIKLLKPKEFDLTLNPWLTGFNDADGYFYTGFQKHKNSQWLKFHLELSQKDSYILDIIKKYFKTGGILKRDYKSGATAYIYKAQSSKAMKPFIEYFNNYQPLSTRRYKQYLLLNIAYLLKLNKLHMLTNSLLMLKELMLLQSVKNMSLEMKNELNNRVKIIINKTHYNNIE", "length": 354, "header": "sp|Q9ZZX0-1|AI5B_YEAST Isoform 1 of Intron-encoded DNA endonuclease aI5 beta OS=Saccharomyces cerevisiae S288C OX=559292 GN=AI5_BETA PE=3 SV=1 CANONICAL=Q9ZZX0-1" }, "isoforms": [ { "isoform_ac": "Q9ZZX0-1", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0/entry#Q9ZZX0-1", "sequence": { "sequence": 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mitochondrial introns in the cob-box and coxI genes require the same MRS1/PET157 nuclear gene product for splicing.", "journal": "Curr. Genet.", "date": "1990", "authors": "Bousquet I, Dujardin G, Poyton R O, Slonimski P P", "evidence": [ { "database": "UniProtKB", "id": "Q9ZZX0", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0" } ], "reference": [ { "type": "PubMed", "id": "1699677", "url": "https://glygen.org/publication/PubMed/1699677" } ] }, { "title": "The nuclear SUV3-1 mutation affects a variety of post-transcriptional processes in yeast mitochondria.", "journal": "Nucleic Acids Res.", "date": "1990", "authors": "Conrad-Webb H, Perlman P S, Zhu H, Butow R A", "evidence": [ { "database": "UniProtKB", "id": "Q9ZZX0", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0" } ], "reference": [ { "type": "PubMed", "id": "2158076", "url": "https://glygen.org/publication/PubMed/2158076" } ] }, { "title": "The reference genome sequence of Saccharomyces cerevisiae: Then and now.", "journal": "G3 (Bethesda)", "date": "2014", "authors": "Engel Stacia R, Dietrich Fred S, Fisk Dianna G, Binkley Gail, Balakrishnan Rama, Costanzo Maria C, Dwight Selina S, Hitz Benjamin C, Karra Kalpana, Nash Robert S, Weng Shuai, Wong Edith D, Lloyd Paul, Skrzypek Marek S, Miyasato Stuart R, Simison Matt, Cherry J Michael", "evidence": [ { "database": "UniProtKB", "id": "Q9ZZX0", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0" } ], "reference": [ { "type": "PubMed", "id": "24374639", "url": "https://glygen.org/publication/PubMed/24374639" } ] }, { "title": "Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I.", "journal": "EMBO J.", "date": "1989", "authors": "Valencik M L, Kloeckener-Gruissem B, Poyton R O, McEwen J E", "evidence": [ { "database": "UniProtKB", "id": "Q9ZZX0", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0" } ], "reference": [ { "type": "PubMed", "id": "2555177", "url": "https://glygen.org/publication/PubMed/2555177" } ] }, { "title": "MSS18, a yeast nuclear gene involved in the splicing of intron aI5 beta of the mitochondrial cox1 transcript.", "journal": "EMBO J.", "date": "1988", "authors": "S\u00e9raphin B, Simon M, Faye G", "evidence": [ { "database": "UniProtKB", "id": "Q9ZZX0", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0" } ], "reference": [ { "type": "PubMed", "id": "2842150", "url": "https://glygen.org/publication/PubMed/2842150" } ] }, { "title": "The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae.", "journal": "FEBS Lett.", "date": "1998", "authors": "Foury F, Roganti T, Lecrenier N, Purnelle B", "evidence": [ { "database": "UniProtKB", "id": "Q9ZZX0", "url": "https://www.uniprot.org/uniprotkb/Q9ZZX0" } ], "reference": [ { "type": "PubMed", "id": "9872396", "url": "https://glygen.org/publication/PubMed/9872396" } ] } ], "pathway": [ { "id": "sce:Q0075", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?sce:Q0075", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, 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